Incidental Mutation 'R6753:Aatk'
| ID |
530913 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Aatk
|
| Ensembl Gene |
ENSMUSG00000025375 |
| Gene Name |
apoptosis-associated tyrosine kinase |
| Synonyms |
AATYK1 |
| MMRRC Submission |
044870-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.122)
|
| Stock # |
R6753 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
11 |
| Chromosomal Location |
120007313-120047167 bp(-) (GRCm38) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
G to A
at 120010151 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Proline to Serine
at position 1083
(P1083S)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000099309
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000026436]
[ENSMUST00000064307]
[ENSMUST00000103019]
[ENSMUST00000103020]
[ENSMUST00000106233]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000026436
|
| SMART Domains |
Protein: ENSMUSP00000026436
Gene: ENSMUSG00000025372
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:IMD
|
17 |
237 |
6e-101 |
PFAM |
|
PDB:4JS0|B
|
261 |
292 |
2e-13 |
PDB |
|
low complexity region
|
321 |
335 |
N/A |
INTRINSIC |
|
SH3
|
378 |
437 |
9.77e-11 |
SMART |
|
low complexity region
|
459 |
471 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000064307
AA Change: P1140S
PolyPhen 2
Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
|
| SMART Domains |
Protein: ENSMUSP00000067181
Gene: ENSMUSG00000025375
AA Change: P1140S
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
20 |
N/A |
INTRINSIC |
|
low complexity region
|
30 |
49 |
N/A |
INTRINSIC |
|
Pfam:Pkinase_Tyr
|
135 |
405 |
3.9e-63 |
PFAM |
|
Pfam:Pkinase
|
136 |
404 |
2.6e-33 |
PFAM |
|
low complexity region
|
425 |
457 |
N/A |
INTRINSIC |
|
low complexity region
|
502 |
514 |
N/A |
INTRINSIC |
|
low complexity region
|
615 |
624 |
N/A |
INTRINSIC |
|
low complexity region
|
647 |
666 |
N/A |
INTRINSIC |
|
low complexity region
|
684 |
695 |
N/A |
INTRINSIC |
|
low complexity region
|
808 |
819 |
N/A |
INTRINSIC |
|
low complexity region
|
913 |
927 |
N/A |
INTRINSIC |
|
low complexity region
|
934 |
943 |
N/A |
INTRINSIC |
|
low complexity region
|
985 |
1004 |
N/A |
INTRINSIC |
|
low complexity region
|
1063 |
1082 |
N/A |
INTRINSIC |
|
low complexity region
|
1085 |
1096 |
N/A |
INTRINSIC |
|
low complexity region
|
1160 |
1174 |
N/A |
INTRINSIC |
|
low complexity region
|
1179 |
1204 |
N/A |
INTRINSIC |
|
low complexity region
|
1319 |
1333 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000083666
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000103019
AA Change: P1083S
PolyPhen 2
Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
|
| SMART Domains |
Protein: ENSMUSP00000099308
Gene: ENSMUSG00000025375
AA Change: P1083S
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Pkinase
|
78 |
347 |
3e-36 |
PFAM |
|
Pfam:Pkinase_Tyr
|
78 |
348 |
1.9e-62 |
PFAM |
|
low complexity region
|
368 |
400 |
N/A |
INTRINSIC |
|
low complexity region
|
445 |
457 |
N/A |
INTRINSIC |
|
low complexity region
|
558 |
567 |
N/A |
INTRINSIC |
|
low complexity region
|
590 |
609 |
N/A |
INTRINSIC |
|
low complexity region
|
627 |
638 |
N/A |
INTRINSIC |
|
low complexity region
|
751 |
762 |
N/A |
INTRINSIC |
|
low complexity region
|
856 |
870 |
N/A |
INTRINSIC |
|
low complexity region
|
877 |
886 |
N/A |
INTRINSIC |
|
low complexity region
|
928 |
947 |
N/A |
INTRINSIC |
|
low complexity region
|
1006 |
1025 |
N/A |
INTRINSIC |
|
low complexity region
|
1028 |
1039 |
N/A |
INTRINSIC |
|
low complexity region
|
1103 |
1117 |
N/A |
INTRINSIC |
|
low complexity region
|
1122 |
1147 |
N/A |
INTRINSIC |
|
low complexity region
|
1262 |
1276 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000103020
AA Change: P1083S
PolyPhen 2
Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
|
| SMART Domains |
Protein: ENSMUSP00000099309
Gene: ENSMUSG00000025375
AA Change: P1083S
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Pkinase
|
78 |
347 |
3e-36 |
PFAM |
|
Pfam:Pkinase_Tyr
|
78 |
348 |
1.9e-62 |
PFAM |
|
low complexity region
|
368 |
400 |
N/A |
INTRINSIC |
|
low complexity region
|
445 |
457 |
N/A |
INTRINSIC |
|
low complexity region
|
558 |
567 |
N/A |
INTRINSIC |
|
low complexity region
|
590 |
609 |
N/A |
INTRINSIC |
|
low complexity region
|
627 |
638 |
N/A |
INTRINSIC |
|
low complexity region
|
751 |
762 |
N/A |
INTRINSIC |
|
low complexity region
|
856 |
870 |
N/A |
INTRINSIC |
|
low complexity region
|
877 |
886 |
N/A |
INTRINSIC |
|
low complexity region
|
928 |
947 |
N/A |
INTRINSIC |
|
low complexity region
|
1006 |
1025 |
N/A |
INTRINSIC |
|
low complexity region
|
1028 |
1039 |
N/A |
INTRINSIC |
|
low complexity region
|
1103 |
1117 |
N/A |
INTRINSIC |
|
low complexity region
|
1122 |
1147 |
N/A |
INTRINSIC |
|
low complexity region
|
1262 |
1276 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000106233
|
| SMART Domains |
Protein: ENSMUSP00000101840
Gene: ENSMUSG00000025372
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:IMD
|
17 |
237 |
1.6e-98 |
PFAM |
|
PDB:4JS0|B
|
261 |
292 |
8e-14 |
PDB |
|
low complexity region
|
321 |
335 |
N/A |
INTRINSIC |
|
SH3
|
378 |
437 |
9.77e-11 |
SMART |
|
low complexity region
|
459 |
471 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000132575
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000136386
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000142959
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000150730
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000198674
|
| Meta Mutation Damage Score |
0.0794 |
| Coding Region Coverage |
- 1x: 99.9%
- 3x: 99.6%
- 10x: 98.3%
- 20x: 95.1%
|
| Validation Efficiency |
99% (68/69) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene contains a tyrosine kinase domain at the N-terminus and a proline-rich domain at the C-terminus. This gene is induced during apoptosis, and expression of this gene may be a necessary pre-requisite for the induction of growth arrest and/or apoptosis of myeloid precursor cells. This gene has been shown to produce neuronal differentiation in a neuroblastoma cell line. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2011]
PHENOTYPE: Mice homozygous for a knock-out allele exhibit decreased brain size, longer axons and fewer neurites. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 64 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abcb5 |
T |
A |
12: 118,944,906 (GRCm38) |
N101I |
possibly damaging |
Het |
| Adrb2 |
A |
G |
18: 62,179,553 (GRCm38) |
V67A |
possibly damaging |
Het |
| Agk |
T |
A |
6: 40,368,570 (GRCm38) |
|
probably null |
Het |
| Akap10 |
A |
T |
11: 61,886,777 (GRCm38) |
M586K |
probably damaging |
Het |
| Akt3 |
A |
T |
1: 177,050,190 (GRCm38) |
Y337* |
probably null |
Het |
| Armc1 |
A |
G |
3: 19,144,398 (GRCm38) |
F133L |
possibly damaging |
Het |
| Bank1 |
T |
C |
3: 136,093,308 (GRCm38) |
E424G |
probably damaging |
Het |
| Cacna1a |
A |
G |
8: 84,580,205 (GRCm38) |
E1363G |
probably damaging |
Het |
| Cacna1d |
C |
A |
14: 30,042,786 (GRCm38) |
A2076S |
probably damaging |
Het |
| Ccdc73 |
T |
A |
2: 104,991,524 (GRCm38) |
L606* |
probably null |
Het |
| Ccdc8 |
C |
T |
7: 16,996,637 (GRCm38) |
Q684* |
probably null |
Het |
| Ces1b |
T |
A |
8: 93,067,020 (GRCm38) |
K314* |
probably null |
Het |
| Ces1e |
T |
A |
8: 93,215,128 (GRCm38) |
N238I |
probably damaging |
Het |
| Chd4 |
A |
G |
6: 125,114,300 (GRCm38) |
N1238S |
probably benign |
Het |
| Cmtr2 |
T |
A |
8: 110,222,979 (GRCm38) |
D640E |
probably damaging |
Het |
| Col7a1 |
C |
T |
9: 108,958,128 (GRCm38) |
T559I |
unknown |
Het |
| Comt |
T |
C |
16: 18,408,021 (GRCm38) |
K205R |
probably benign |
Het |
| Dbp |
A |
T |
7: 45,708,404 (GRCm38) |
E232V |
probably damaging |
Het |
| Dcbld2 |
A |
G |
16: 58,456,130 (GRCm38) |
T470A |
possibly damaging |
Het |
| Eml6 |
T |
A |
11: 29,754,987 (GRCm38) |
D1519V |
probably damaging |
Het |
| Evpl |
T |
A |
11: 116,237,906 (GRCm38) |
H31L |
possibly damaging |
Het |
| Exoc1 |
T |
A |
5: 76,563,339 (GRCm38) |
I86N |
probably damaging |
Het |
| Fat3 |
C |
T |
9: 15,915,061 (GRCm38) |
E4532K |
possibly damaging |
Het |
| Fgfr3 |
T |
C |
5: 33,732,159 (GRCm38) |
S301P |
probably benign |
Het |
| Gas2l1 |
C |
T |
11: 5,064,254 (GRCm38) |
V69I |
probably damaging |
Het |
| Gm2042 |
T |
A |
12: 87,958,084 (GRCm38) |
I107K |
probably damaging |
Het |
| Gucy1b1 |
T |
C |
3: 82,039,747 (GRCm38) |
D385G |
probably null |
Het |
| Ints1 |
T |
A |
5: 139,765,175 (GRCm38) |
E824D |
probably damaging |
Het |
| Itfg1 |
T |
C |
8: 85,835,078 (GRCm38) |
D142G |
probably benign |
Het |
| Jaml |
A |
G |
9: 45,107,379 (GRCm38) |
N359D |
probably benign |
Het |
| Kcnh7 |
T |
A |
2: 62,850,377 (GRCm38) |
I289L |
probably benign |
Het |
| Klf12 |
G |
A |
14: 100,109,776 (GRCm38) |
Q40* |
probably null |
Het |
| Mcm4 |
A |
C |
16: 15,629,362 (GRCm38) |
N579K |
possibly damaging |
Het |
| Mfsd2b |
A |
T |
12: 4,867,358 (GRCm38) |
F179I |
possibly damaging |
Het |
| Mmp11 |
C |
T |
10: 75,928,374 (GRCm38) |
V86M |
probably damaging |
Het |
| Mogs |
T |
C |
6: 83,115,882 (GRCm38) |
V101A |
probably damaging |
Het |
| Narf |
T |
A |
11: 121,242,626 (GRCm38) |
H84Q |
probably benign |
Het |
| Or5ak4 |
C |
A |
2: 85,331,798 (GRCm38) |
M33I |
probably benign |
Het |
| Otog |
A |
C |
7: 46,249,071 (GRCm38) |
E204D |
probably benign |
Het |
| Parp8 |
G |
A |
13: 116,895,115 (GRCm38) |
H354Y |
possibly damaging |
Het |
| Pcnx1 |
C |
A |
12: 81,964,480 (GRCm38) |
D1238E |
probably damaging |
Het |
| Pi4ka |
A |
G |
16: 17,376,982 (GRCm38) |
L184P |
possibly damaging |
Het |
| Pkd1l3 |
C |
T |
8: 109,624,449 (GRCm38) |
T642I |
probably damaging |
Het |
| Pkhd1l1 |
G |
A |
15: 44,589,663 (GRCm38) |
E3995K |
probably benign |
Het |
| Prdm9 |
A |
T |
17: 15,544,956 (GRCm38) |
Y521N |
probably benign |
Het |
| Prex2 |
A |
G |
1: 11,184,456 (GRCm38) |
S1105G |
probably damaging |
Het |
| Prss35 |
T |
A |
9: 86,756,100 (GRCm38) |
F308I |
probably damaging |
Het |
| Rab22a |
C |
T |
2: 173,701,055 (GRCm38) |
A167V |
probably benign |
Het |
| Rims2 |
A |
G |
15: 39,566,973 (GRCm38) |
Q871R |
possibly damaging |
Het |
| Rorb |
A |
T |
19: 18,957,247 (GRCm38) |
M253K |
probably benign |
Het |
| Ryr3 |
T |
C |
2: 112,652,610 (GRCm38) |
D4269G |
probably damaging |
Het |
| Snx11 |
T |
C |
11: 96,769,906 (GRCm38) |
|
probably benign |
Het |
| Son |
A |
G |
16: 91,657,188 (GRCm38) |
Q941R |
probably damaging |
Het |
| Sptbn2 |
G |
T |
19: 4,747,785 (GRCm38) |
R1880L |
probably benign |
Het |
| Sun1 |
G |
A |
5: 139,215,259 (GRCm38) |
|
probably null |
Het |
| Tprn |
A |
G |
2: 25,264,038 (GRCm38) |
R451G |
probably benign |
Het |
| Trbv30 |
T |
A |
6: 41,281,377 (GRCm38) |
M1K |
probably null |
Het |
| Ttn |
C |
A |
2: 76,738,221 (GRCm38) |
G25697W |
probably damaging |
Het |
| Ubb |
T |
G |
11: 62,551,527 (GRCm38) |
|
probably null |
Het |
| Unc13b |
C |
T |
4: 43,239,331 (GRCm38) |
R1038C |
probably damaging |
Het |
| Usp7 |
T |
C |
16: 8,696,911 (GRCm38) |
M687V |
probably benign |
Het |
| Zfp160 |
G |
A |
17: 21,020,734 (GRCm38) |
M21I |
probably benign |
Het |
| Zfp868 |
T |
C |
8: 69,612,096 (GRCm38) |
N196S |
probably benign |
Het |
| Zup1 |
A |
T |
10: 33,928,029 (GRCm38) |
I483N |
probably damaging |
Het |
|
| Other mutations in Aatk |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00497:Aatk
|
APN |
11 |
120,010,186 (GRCm38) |
missense |
probably benign |
0.02 |
|
IGL00953:Aatk
|
APN |
11 |
120,011,221 (GRCm38) |
missense |
probably benign |
0.00 |
|
IGL01019:Aatk
|
APN |
11 |
120,012,275 (GRCm38) |
missense |
probably benign |
|
|
IGL01758:Aatk
|
APN |
11 |
120,010,819 (GRCm38) |
missense |
possibly damaging |
0.86 |
|
IGL02377:Aatk
|
APN |
11 |
120,046,863 (GRCm38) |
utr 5 prime |
probably benign |
|
|
IGL02902:Aatk
|
APN |
11 |
120,011,777 (GRCm38) |
missense |
probably benign |
0.00 |
|
IGL03067:Aatk
|
APN |
11 |
120,010,083 (GRCm38) |
missense |
probably benign |
0.00 |
|
IGL03116:Aatk
|
APN |
11 |
120,016,751 (GRCm38) |
missense |
probably benign |
0.14 |
|
IGL03279:Aatk
|
APN |
11 |
120,013,678 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL03405:Aatk
|
APN |
11 |
120,016,403 (GRCm38) |
missense |
probably benign |
0.02 |
|
PIT4366001:Aatk
|
UTSW |
11 |
120,010,960 (GRCm38) |
missense |
possibly damaging |
0.55 |
|
PIT4802001:Aatk
|
UTSW |
11 |
120,011,346 (GRCm38) |
missense |
probably benign |
|
|
R0101:Aatk
|
UTSW |
11 |
120,010,913 (GRCm38) |
missense |
probably benign |
0.19 |
|
R0497:Aatk
|
UTSW |
11 |
120,018,780 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R0535:Aatk
|
UTSW |
11 |
120,010,193 (GRCm38) |
missense |
probably benign |
0.00 |
|
R0638:Aatk
|
UTSW |
11 |
120,009,922 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0939:Aatk
|
UTSW |
11 |
120,012,143 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R1475:Aatk
|
UTSW |
11 |
120,010,888 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R1840:Aatk
|
UTSW |
11 |
120,013,732 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1865:Aatk
|
UTSW |
11 |
120,010,222 (GRCm38) |
missense |
probably benign |
0.00 |
|
R1982:Aatk
|
UTSW |
11 |
120,013,514 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2027:Aatk
|
UTSW |
11 |
120,009,317 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2115:Aatk
|
UTSW |
11 |
120,009,736 (GRCm38) |
missense |
probably benign |
|
|
R2220:Aatk
|
UTSW |
11 |
120,012,177 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2264:Aatk
|
UTSW |
11 |
120,010,274 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2504:Aatk
|
UTSW |
11 |
120,018,855 (GRCm38) |
missense |
probably benign |
0.00 |
|
R3872:Aatk
|
UTSW |
11 |
120,010,219 (GRCm38) |
missense |
possibly damaging |
0.71 |
|
R4551:Aatk
|
UTSW |
11 |
120,011,569 (GRCm38) |
missense |
probably benign |
0.03 |
|
R4657:Aatk
|
UTSW |
11 |
120,013,478 (GRCm38) |
missense |
possibly damaging |
0.69 |
|
R4744:Aatk
|
UTSW |
11 |
120,016,122 (GRCm38) |
missense |
possibly damaging |
0.64 |
|
R4924:Aatk
|
UTSW |
11 |
120,011,525 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5063:Aatk
|
UTSW |
11 |
120,010,489 (GRCm38) |
missense |
probably benign |
0.07 |
|
R5223:Aatk
|
UTSW |
11 |
120,013,452 (GRCm38) |
missense |
possibly damaging |
0.95 |
|
R5243:Aatk
|
UTSW |
11 |
120,016,768 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5376:Aatk
|
UTSW |
11 |
120,012,034 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R5442:Aatk
|
UTSW |
11 |
120,018,768 (GRCm38) |
missense |
probably benign |
0.02 |
|
R5550:Aatk
|
UTSW |
11 |
120,009,303 (GRCm38) |
missense |
probably benign |
0.42 |
|
R5678:Aatk
|
UTSW |
11 |
120,010,154 (GRCm38) |
missense |
probably benign |
0.00 |
|
R5932:Aatk
|
UTSW |
11 |
120,021,533 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6026:Aatk
|
UTSW |
11 |
120,012,364 (GRCm38) |
missense |
possibly damaging |
0.65 |
|
R6129:Aatk
|
UTSW |
11 |
120,021,533 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6409:Aatk
|
UTSW |
11 |
120,011,732 (GRCm38) |
missense |
probably benign |
0.01 |
|
R6477:Aatk
|
UTSW |
11 |
120,018,870 (GRCm38) |
missense |
probably benign |
0.00 |
|
R6478:Aatk
|
UTSW |
11 |
120,010,991 (GRCm38) |
missense |
probably benign |
0.00 |
|
R6749:Aatk
|
UTSW |
11 |
120,010,774 (GRCm38) |
missense |
possibly damaging |
0.58 |
|
R6787:Aatk
|
UTSW |
11 |
120,010,682 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6852:Aatk
|
UTSW |
11 |
120,010,468 (GRCm38) |
missense |
probably benign |
0.10 |
|
R7114:Aatk
|
UTSW |
11 |
120,009,619 (GRCm38) |
missense |
probably benign |
|
|
R7557:Aatk
|
UTSW |
11 |
120,009,430 (GRCm38) |
missense |
possibly damaging |
0.73 |
|
R7818:Aatk
|
UTSW |
11 |
120,021,455 (GRCm38) |
missense |
probably benign |
|
|
R7954:Aatk
|
UTSW |
11 |
120,012,343 (GRCm38) |
missense |
possibly damaging |
0.51 |
|
R8176:Aatk
|
UTSW |
11 |
120,016,415 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R8420:Aatk
|
UTSW |
11 |
120,046,920 (GRCm38) |
missense |
unknown |
|
|
R8963:Aatk
|
UTSW |
11 |
120,012,137 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9090:Aatk
|
UTSW |
11 |
120,011,114 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R9167:Aatk
|
UTSW |
11 |
120,011,126 (GRCm38) |
missense |
possibly damaging |
0.90 |
|
R9271:Aatk
|
UTSW |
11 |
120,011,114 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R9357:Aatk
|
UTSW |
11 |
120,010,870 (GRCm38) |
missense |
probably benign |
0.01 |
|
R9373:Aatk
|
UTSW |
11 |
120,015,517 (GRCm38) |
missense |
possibly damaging |
0.95 |
|
R9420:Aatk
|
UTSW |
11 |
120,021,451 (GRCm38) |
missense |
probably benign |
0.01 |
|
R9423:Aatk
|
UTSW |
11 |
120,010,694 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9476:Aatk
|
UTSW |
11 |
120,010,268 (GRCm38) |
missense |
probably benign |
0.01 |
|
R9510:Aatk
|
UTSW |
11 |
120,010,268 (GRCm38) |
missense |
probably benign |
0.01 |
|
R9519:Aatk
|
UTSW |
11 |
120,021,483 (GRCm38) |
start gained |
probably benign |
|
|
R9605:Aatk
|
UTSW |
11 |
120,011,383 (GRCm38) |
missense |
possibly damaging |
0.88 |
|
R9649:Aatk
|
UTSW |
11 |
120,010,907 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9766:Aatk
|
UTSW |
11 |
120,011,739 (GRCm38) |
missense |
probably benign |
0.00 |
|
X0064:Aatk
|
UTSW |
11 |
120,011,176 (GRCm38) |
splice site |
probably null |
|
|
| Predicted Primers |
PCR Primer
(F):5'- CGTAGATTTCGGGCACTCTG -3'
(R):5'- TTTCCCAGGTCTGCAGTGTC -3'
Sequencing Primer
(F):5'- GCACTCTGGCTCTCAGC -3'
(R):5'- CTCCACAGCAGTCAGAGGAG -3'
|
| Posted On |
2018-08-01 |
Incidental Mutation