Incidental Mutation 'IGL00487:Vmn1r180'
| ID |
5310 |
| Institutional Source |
Australian Phenomics Network
(link to record)
|
| Gene Symbol |
Vmn1r180
|
| Ensembl Gene |
ENSMUSG00000092473 |
| Gene Name |
vomeronasal 1 receptor 180 |
| Synonyms |
V1rd16, LOC232962 |
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.054)
|
| Stock # |
IGL00487
|
| Quality Score |
|
|
Status
|
|
| Chromosome |
7 |
| Chromosomal Location |
23651812-23652781 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 23651948 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Histidine to Leucine
at position 37
(H37L)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000134362
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000173816]
|
| AlphaFold |
B9EK86 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000173816
AA Change: H37L
PolyPhen 2
Score 0.363 (Sensitivity: 0.90; Specificity: 0.89)
|
| SMART Domains |
Protein: ENSMUSP00000134362
Gene: ENSMUSG00000092473
AA Change: H37L
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:TAS2R
|
8 |
298 |
2.9e-15 |
PFAM |
|
Pfam:7tm_1
|
31 |
286 |
6.7e-9 |
PFAM |
|
Pfam:V1R
|
41 |
297 |
1.4e-17 |
PFAM |
|
| Coding Region Coverage |
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 15 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abca5 |
T |
A |
11: 110,200,276 (GRCm39) |
|
probably null |
Het |
| Cfap251 |
T |
G |
5: 123,412,240 (GRCm39) |
I84S |
probably damaging |
Het |
| Dusp23 |
T |
C |
1: 172,459,199 (GRCm39) |
|
probably benign |
Het |
| Invs |
C |
T |
4: 48,407,689 (GRCm39) |
Q555* |
probably null |
Het |
| Mak16 |
T |
C |
8: 31,656,778 (GRCm39) |
N9D |
probably benign |
Het |
| Mrps7 |
T |
C |
11: 115,495,684 (GRCm39) |
I74T |
possibly damaging |
Het |
| Nlrp4a |
T |
G |
7: 26,149,410 (GRCm39) |
V339G |
possibly damaging |
Het |
| Nucb1 |
A |
G |
7: 45,151,075 (GRCm39) |
L102P |
probably damaging |
Het |
| Pdp2 |
T |
C |
8: 105,320,829 (GRCm39) |
M226T |
probably benign |
Het |
| Pik3r2 |
T |
C |
8: 71,223,073 (GRCm39) |
D449G |
probably damaging |
Het |
| Rnf157 |
G |
A |
11: 116,253,181 (GRCm39) |
P76S |
probably benign |
Het |
| Senp6 |
C |
A |
9: 80,021,120 (GRCm39) |
Q267K |
probably damaging |
Het |
| Slc9a2 |
A |
G |
1: 40,781,818 (GRCm39) |
E349G |
probably damaging |
Het |
| Snx14 |
G |
T |
9: 88,284,243 (GRCm39) |
S475Y |
probably damaging |
Het |
| Xrn1 |
A |
T |
9: 95,921,002 (GRCm39) |
H1371L |
probably benign |
Het |
|
| Other mutations in Vmn1r180 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01309:Vmn1r180
|
APN |
7 |
23,652,424 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01793:Vmn1r180
|
APN |
7 |
23,652,668 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02653:Vmn1r180
|
APN |
7 |
23,652,500 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03277:Vmn1r180
|
APN |
7 |
23,652,710 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL03352:Vmn1r180
|
APN |
7 |
23,652,077 (GRCm39) |
nonsense |
probably null |
|
|
R1298:Vmn1r180
|
UTSW |
7 |
23,652,572 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R1701:Vmn1r180
|
UTSW |
7 |
23,652,395 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R1702:Vmn1r180
|
UTSW |
7 |
23,652,394 (GRCm39) |
missense |
possibly damaging |
0.52 |
|
R2122:Vmn1r180
|
UTSW |
7 |
23,652,566 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4241:Vmn1r180
|
UTSW |
7 |
23,652,298 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5683:Vmn1r180
|
UTSW |
7 |
23,652,635 (GRCm39) |
missense |
possibly damaging |
0.58 |
|
R7241:Vmn1r180
|
UTSW |
7 |
23,651,891 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7522:Vmn1r180
|
UTSW |
7 |
23,652,685 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8749:Vmn1r180
|
UTSW |
7 |
23,652,415 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8991:Vmn1r180
|
UTSW |
7 |
23,652,076 (GRCm39) |
missense |
probably benign |
0.06 |
|
R9442:Vmn1r180
|
UTSW |
7 |
23,651,620 (GRCm39) |
start gained |
probably benign |
|
|
| Posted On |
2012-04-20 |
Incidental Mutation