Incidental Mutation 'IGL00487:Vmn1r180'
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ID5310
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Vmn1r180
Ensembl Gene ENSMUSG00000092473
Gene Namevomeronasal 1 receptor 180
SynonymsLOC232962, V1rd16
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.060) question?
Stock #IGL00487
Quality Score
Status
Chromosome7
Chromosomal Location23950632-23955691 bp(+) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) A to T at 23952523 bp
ZygosityHeterozygous
Amino Acid Change Histidine to Leucine at position 37 (H37L)
Ref Sequence ENSEMBL: ENSMUSP00000134362 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000173816]
Predicted Effect probably benign
Transcript: ENSMUST00000173816
AA Change: H37L

PolyPhen 2 Score 0.363 (Sensitivity: 0.90; Specificity: 0.89)
SMART Domains Protein: ENSMUSP00000134362
Gene: ENSMUSG00000092473
AA Change: H37L

DomainStartEndE-ValueType
Pfam:TAS2R 8 298 2.9e-15 PFAM
Pfam:7tm_1 31 286 6.7e-9 PFAM
Pfam:V1R 41 297 1.4e-17 PFAM
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 15 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Abca5 T A 11: 110,309,450 probably null Het
Dusp23 T C 1: 172,631,632 probably benign Het
Invs C T 4: 48,407,689 Q555* probably null Het
Mak16 T C 8: 31,166,750 N9D probably benign Het
Mrps7 T C 11: 115,604,858 I74T possibly damaging Het
Nlrp4a T G 7: 26,449,985 V339G possibly damaging Het
Nucb1 A G 7: 45,501,651 L102P probably damaging Het
Pdp2 T C 8: 104,594,197 M226T probably benign Het
Pik3r2 T C 8: 70,770,429 D449G probably damaging Het
Rnf157 G A 11: 116,362,355 P76S probably benign Het
Senp6 C A 9: 80,113,838 Q267K probably damaging Het
Slc9a2 A G 1: 40,742,658 E349G probably damaging Het
Snx14 G T 9: 88,402,190 S475Y probably damaging Het
Wdr66 T G 5: 123,274,177 I84S probably damaging Het
Xrn1 A T 9: 96,038,949 H1371L probably benign Het
Other mutations in Vmn1r180
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01309:Vmn1r180 APN 7 23952999 missense probably damaging 1.00
IGL01793:Vmn1r180 APN 7 23953243 missense probably benign 0.00
IGL02653:Vmn1r180 APN 7 23953075 missense probably damaging 1.00
IGL03277:Vmn1r180 APN 7 23953285 missense probably damaging 0.99
IGL03352:Vmn1r180 APN 7 23952652 nonsense probably null
R1298:Vmn1r180 UTSW 7 23953147 missense possibly damaging 0.84
R1701:Vmn1r180 UTSW 7 23952970 missense possibly damaging 0.84
R1702:Vmn1r180 UTSW 7 23952969 missense possibly damaging 0.52
R2122:Vmn1r180 UTSW 7 23953141 missense probably damaging 1.00
R4241:Vmn1r180 UTSW 7 23952873 missense probably damaging 1.00
R5683:Vmn1r180 UTSW 7 23953210 missense possibly damaging 0.58
R7241:Vmn1r180 UTSW 7 23952466 missense probably damaging 0.96
R7522:Vmn1r180 UTSW 7 23953260 missense probably damaging 1.00
R8749:Vmn1r180 UTSW 7 23952990 missense probably damaging 1.00
Posted On2012-04-20