Incidental Mutation 'IGL00474:Vmn1r120'
ID5316
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Vmn1r120
Ensembl Gene ENSMUSG00000093986
Gene Namevomeronasal 1 receptor 120
SynonymsGm5730
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.057) question?
Stock #IGL00474
Quality Score
Status
Chromosome7
Chromosomal Location21052867-21053784 bp(-) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) T to A at 21053010 bp
ZygosityHeterozygous
Amino Acid Change Isoleucine to Phenylalanine at position 259 (I259F)
Ref Sequence ENSEMBL: ENSMUSP00000100837 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000105202]
Predicted Effect probably benign
Transcript: ENSMUST00000105202
AA Change: I259F

PolyPhen 2 Score 0.002 (Sensitivity: 0.99; Specificity: 0.30)
SMART Domains Protein: ENSMUSP00000100837
Gene: ENSMUSG00000093986
AA Change: I259F

DomainStartEndE-ValueType
Pfam:TAS2R 8 297 2.3e-15 PFAM
Pfam:7tm_1 31 286 3.6e-6 PFAM
Pfam:V1R 41 296 6.4e-13 PFAM
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 10 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Adam12 T C 7: 133,909,881 K730R possibly damaging Het
Adgrf4 T C 17: 42,675,759 I36M probably damaging Het
Atp2a1 A T 7: 126,450,294 C525* probably null Het
Col11a1 A C 3: 114,066,533 M203L unknown Het
Duox2 T A 2: 122,283,575 M1159L probably benign Het
Harbi1 T G 2: 91,712,626 V144G probably damaging Het
Kcp A G 6: 29,482,657 V1471A probably benign Het
Lrig1 G T 6: 94,611,404 T588K probably damaging Het
Lyst A G 13: 13,643,536 I1264V possibly damaging Het
Slc4a11 A T 2: 130,688,138 M240K probably benign Het
Other mutations in Vmn1r120
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL02533:Vmn1r120 APN 7 21053138 missense probably damaging 1.00
IGL03261:Vmn1r120 APN 7 21053525 missense probably damaging 1.00
R0539:Vmn1r120 UTSW 7 21053472 missense probably damaging 0.99
R0973:Vmn1r120 UTSW 7 21053016 missense probably damaging 1.00
R1831:Vmn1r120 UTSW 7 21053631 missense probably benign
R2034:Vmn1r120 UTSW 7 21052958 missense possibly damaging 0.56
R2149:Vmn1r120 UTSW 7 21052964 missense probably damaging 0.98
R3437:Vmn1r120 UTSW 7 21053657 missense probably damaging 1.00
R5449:Vmn1r120 UTSW 7 21053149 missense possibly damaging 0.53
R5548:Vmn1r120 UTSW 7 21053557 missense probably benign 0.01
R5730:Vmn1r120 UTSW 7 21053009 missense possibly damaging 0.80
R6305:Vmn1r120 UTSW 7 21053606 missense possibly damaging 0.95
R7348:Vmn1r120 UTSW 7 21053452 missense probably damaging 1.00
R8435:Vmn1r120 UTSW 7 21053632 missense probably benign 0.44
R8486:Vmn1r120 UTSW 7 21053102 missense probably benign
Posted On2012-04-20