Mutagenetix > Incidental Mutation

Incidental Mutation 'R6785:Igsf10'

531604

Institutional Source

Beutler Lab

Gene Symbol

Igsf10

Ensembl Gene

ENSMUSG00000036334

Gene Name

immunoglobulin superfamily, member 10

Synonyms

6530405F15Rik, CMF608, Adlican2

MMRRC Submission

044899-MU

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.193) question?

Stock #

R6785 (G1)

Quality Score

225.009

Status

Validated

Chromosome

Chromosomal Location

59224156-59251815 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

G to T at 59226665 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Proline to Glutamine at position 2336 (P2336Q)

Ref Sequence

ENSEMBL: ENSMUSP00000141391 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000039419] [ENSMUST00000040325] [ENSMUST00000164225] [ENSMUST00000193455] [ENSMUST00000194546] [ENSMUST00000199659]

AlphaFold

Q3V1M1

Predicted Effect

probably damaging
Transcript: ENSMUST00000039419
AA Change: P2336Q

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)

SMART Domains

Protein: ENSMUSP00000037246
Gene: ENSMUSG00000036334
AA Change: P2336Q

Domain	Start	End	E-Value	Type
signal peptide	1	25	N/A	INTRINSIC
LRRNT	28	61	3.24e-4	SMART
LRR	57	79	9.24e1	SMART
LRR	80	103	2.02e-1	SMART
LRR	104	127	7.16e0	SMART
LRR_TYP	128	151	1.2e-3	SMART
LRR	152	175	1.25e-1	SMART
LRR	188	207	2.33e2	SMART
LRRCT	219	280	4.19e-4	SMART
IGc2	488	558	2.34e-4	SMART
IGc2	586	652	7.88e-11	SMART
low complexity region	917	930	N/A	INTRINSIC
low complexity region	1175	1185	N/A	INTRINSIC
low complexity region	1245	1263	N/A	INTRINSIC
low complexity region	1311	1321	N/A	INTRINSIC
low complexity region	1449	1465	N/A	INTRINSIC
IGc2	1632	1701	7.69e-14	SMART
IGc2	1729	1798	5.07e-14	SMART
IGc2	1826	1895	2.19e-9	SMART
IGc2	1925	1994	4.59e-12	SMART
IGc2	2022	2097	1.33e-8	SMART
IGc2	2125	2191	2.96e-15	SMART
IGc2	2223	2291	2.03e-4	SMART
IGc2	2321	2389	9.99e-13	SMART
IGc2	2416	2484	3.03e-12	SMART
IGc2	2512	2583	7.76e-10	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000040325

SMART Domains

Protein: ENSMUSP00000042269
Gene: ENSMUSG00000056476

Domain	Start	End	E-Value	Type
Med12	101	161	1.71e-24	SMART
low complexity region	216	224	N/A	INTRINSIC
low complexity region	269	278	N/A	INTRINSIC
Pfam:Med12-LCEWAV	282	730	2.6e-207	PFAM
low complexity region	744	758	N/A	INTRINSIC
low complexity region	853	872	N/A	INTRINSIC
low complexity region	1455	1466	N/A	INTRINSIC
low complexity region	1728	1742	N/A	INTRINSIC
low complexity region	1769	1783	N/A	INTRINSIC
Pfam:Med12-PQL	1803	2029	2.3e-14	PFAM
low complexity region	2055	2076	N/A	INTRINSIC
low complexity region	2083	2101	N/A	INTRINSIC
low complexity region	2116	2136	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000164225

SMART Domains

Protein: ENSMUSP00000127038
Gene: ENSMUSG00000056476

Domain	Start	End	E-Value	Type
Med12	101	161	1.71e-24	SMART
low complexity region	216	224	N/A	INTRINSIC
low complexity region	269	278	N/A	INTRINSIC
Pfam:Med12-LCEWAV	283	765	5e-187	PFAM
low complexity region	779	793	N/A	INTRINSIC
low complexity region	888	907	N/A	INTRINSIC
low complexity region	1490	1501	N/A	INTRINSIC
low complexity region	1763	1777	N/A	INTRINSIC
low complexity region	1804	1818	N/A	INTRINSIC
Pfam:Med12-PQL	1840	2063	9.7e-66	PFAM
low complexity region	2090	2111	N/A	INTRINSIC
low complexity region	2118	2136	N/A	INTRINSIC
low complexity region	2151	2171	N/A	INTRINSIC

Predicted Effect

probably damaging
Transcript: ENSMUST00000193455
AA Change: P2336Q

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)

SMART Domains

Protein: ENSMUSP00000141971
Gene: ENSMUSG00000036334
AA Change: P2336Q

Domain	Start	End	E-Value	Type
signal peptide	1	25	N/A	INTRINSIC
LRRNT	28	61	3.24e-4	SMART
LRR	57	79	9.24e1	SMART
LRR	80	103	2.02e-1	SMART
LRR	104	127	7.16e0	SMART
LRR_TYP	128	151	1.2e-3	SMART
LRR	152	175	1.25e-1	SMART
LRR	188	207	2.33e2	SMART
LRRCT	219	280	4.19e-4	SMART
IGc2	488	558	2.34e-4	SMART
IGc2	586	652	7.88e-11	SMART
low complexity region	917	930	N/A	INTRINSIC
low complexity region	1175	1185	N/A	INTRINSIC
low complexity region	1245	1263	N/A	INTRINSIC
low complexity region	1311	1321	N/A	INTRINSIC
low complexity region	1449	1465	N/A	INTRINSIC
IGc2	1632	1701	7.69e-14	SMART
IGc2	1729	1798	5.07e-14	SMART
IGc2	1826	1895	2.19e-9	SMART
IGc2	1925	1994	4.59e-12	SMART
IGc2	2022	2097	1.33e-8	SMART
IGc2	2125	2191	2.96e-15	SMART
IGc2	2223	2291	2.03e-4	SMART
IGc2	2321	2389	9.99e-13	SMART
IGc2	2416	2484	3.03e-12	SMART
IGc2	2512	2583	7.76e-10	SMART

Predicted Effect

probably damaging
Transcript: ENSMUST00000194546
AA Change: P2336Q

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)

SMART Domains

Protein: ENSMUSP00000141391
Gene: ENSMUSG00000036334
AA Change: P2336Q

Domain	Start	End	E-Value	Type
signal peptide	1	25	N/A	INTRINSIC
LRRNT	28	61	3.24e-4	SMART
LRR	57	79	9.24e1	SMART
LRR	80	103	2.02e-1	SMART
LRR	104	127	7.16e0	SMART
LRR_TYP	128	151	1.2e-3	SMART
LRR	152	175	1.25e-1	SMART
LRR	188	207	2.33e2	SMART
LRRCT	219	280	4.19e-4	SMART
IGc2	488	558	2.34e-4	SMART
IGc2	586	652	7.88e-11	SMART
low complexity region	917	930	N/A	INTRINSIC
low complexity region	1175	1185	N/A	INTRINSIC
low complexity region	1245	1263	N/A	INTRINSIC
low complexity region	1311	1321	N/A	INTRINSIC
low complexity region	1449	1465	N/A	INTRINSIC
IGc2	1632	1701	7.69e-14	SMART
IGc2	1729	1798	5.07e-14	SMART
IGc2	1826	1895	2.19e-9	SMART
IGc2	1925	1994	4.59e-12	SMART
IGc2	2022	2097	1.33e-8	SMART
IGc2	2125	2191	2.96e-15	SMART
IGc2	2223	2291	2.03e-4	SMART
IGc2	2321	2389	9.99e-13	SMART
IGc2	2416	2484	3.03e-12	SMART
IGc2	2512	2583	7.76e-10	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000197374

Predicted Effect

probably benign
Transcript: ENSMUST00000199659

SMART Domains

Protein: ENSMUSP00000142903
Gene: ENSMUSG00000056476

Domain	Start	End	E-Value	Type
Med12	101	161	1.71e-24	SMART
low complexity region	216	224	N/A	INTRINSIC
low complexity region	269	278	N/A	INTRINSIC
Pfam:Med12-LCEWAV	282	765	5.5e-209	PFAM
low complexity region	779	793	N/A	INTRINSIC
low complexity region	888	907	N/A	INTRINSIC
low complexity region	1490	1501	N/A	INTRINSIC
low complexity region	1761	1775	N/A	INTRINSIC
low complexity region	1802	1816	N/A	INTRINSIC
Pfam:Med12-PQL	1836	2062	1.7e-15	PFAM
low complexity region	2088	2130	N/A	INTRINSIC
low complexity region	2144	2164	N/A	INTRINSIC

Coding Region Coverage

1x: 99.9%
3x: 99.7%
10x: 98.6%
20x: 96.3%

Validation Efficiency

98% (59/60)

Allele List at MGI

All alleles(2) : Targeted, other(2)

Other mutations in this stock

Total: 61 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Abi1	A	G	2: 22,843,479 (GRCm39)	V316A	probably benign	Het
Acad12	T	C	5: 121,747,908 (GRCm39)	Y170C	probably damaging	Het
Acss2	T	C	2: 155,402,605 (GRCm39)	V587A	probably damaging	Het
Adamtsl3	A	G	7: 82,171,212 (GRCm39)	I422V	probably damaging	Het
Aldh18a1	A	G	19: 40,556,788 (GRCm39)	L375P	probably damaging	Het
B020011L13Rik	A	G	1: 117,728,799 (GRCm39)	D102G	possibly damaging	Het
Cfap74	T	A	4: 155,538,481 (GRCm39)		probably benign	Het
Coa4	G	A	7: 100,188,460 (GRCm39)	V58M	probably damaging	Het
Crybg1	T	C	10: 43,875,167 (GRCm39)	N647S	probably benign	Het
Dync1h1	G	A	12: 110,596,113 (GRCm39)	G1547S	probably damaging	Het
Espnl	A	G	1: 91,249,943 (GRCm39)	D30G	probably benign	Het
Fasl	T	A	1: 161,609,404 (GRCm39)	Y194F	probably benign	Het
Fbxw8	T	C	5: 118,230,754 (GRCm39)	E349G	probably damaging	Het
Gen1	A	G	12: 11,312,531 (GRCm39)	V13A	possibly damaging	Het
Gm4559	A	G	7: 141,827,845 (GRCm39)	C86R	unknown	Het
H2-M9	T	C	17: 36,953,125 (GRCm39)	N61D	probably damaging	Het
H6pd	C	T	4: 150,067,247 (GRCm39)	E380K	possibly damaging	Het
Herc1	TCCC	TCC	9: 66,408,470 (GRCm39)		probably null	Het
Hnrnpd	C	A	5: 100,126,283 (GRCm39)	K67N	probably benign	Het
Hspg2	T	C	4: 137,235,709 (GRCm39)	S170P	probably damaging	Het
Itih3	C	T	14: 30,634,572 (GRCm39)		probably null	Het
Katnb1	T	C	8: 95,822,270 (GRCm39)	Y298H	probably benign	Het
Kif21a	A	T	15: 90,819,933 (GRCm39)	N1610K	probably damaging	Het
Lce1l	A	T	3: 92,757,500 (GRCm39)	C119*	probably null	Het
Lcn2	C	T	2: 32,277,039 (GRCm39)		probably null	Het
Lmf2	A	T	15: 89,236,236 (GRCm39)	S588T	probably benign	Het
Mboat7	A	G	7: 3,688,835 (GRCm39)	L231P	probably benign	Het
Mier2	T	C	10: 79,380,547 (GRCm39)	R288G	probably damaging	Het
Mybbp1a	T	C	11: 72,338,392 (GRCm39)	V694A	probably benign	Het
Ndnf	C	A	6: 65,680,047 (GRCm39)	L109I	probably benign	Het
Nfkb1	C	A	3: 135,321,064 (GRCm39)	E230D	probably benign	Het
Nostrin	A	G	2: 69,014,271 (GRCm39)	K409R	probably benign	Het
Or1j10	A	G	2: 36,266,854 (GRCm39)	Q22R	probably benign	Het
Or1j10	C	A	2: 36,266,963 (GRCm39)	Y58*	probably null	Het
Or8k35	T	A	2: 86,424,765 (GRCm39)	M136L	probably damaging	Het
Pdpr	C	A	8: 111,851,243 (GRCm39)	T534N	probably benign	Het
Plekhf1	G	A	7: 37,921,488 (GRCm39)	Q27*	probably null	Het
Ppp6c	A	T	2: 39,087,593 (GRCm39)	H204Q	probably benign	Het
Prrc2c	T	C	1: 162,536,670 (GRCm39)		probably benign	Het
Prrg2	A	G	7: 44,709,649 (GRCm39)	F83L	probably damaging	Het
Rab11fip3	T	G	17: 26,210,692 (GRCm39)	D938A	probably damaging	Het
Rai1	A	G	11: 60,079,620 (GRCm39)	N1228S	probably benign	Het
Ryr1	G	T	7: 28,764,299 (GRCm39)	T3060K	probably benign	Het
Scube2	A	G	7: 109,409,824 (GRCm39)	I557T	probably benign	Het
Setdb1	C	A	3: 95,233,712 (GRCm39)	R1066L	probably benign	Het
Shoc1	T	C	4: 59,049,066 (GRCm39)	M1100V	probably benign	Het
Slc35f3	T	C	8: 127,121,198 (GRCm39)	V353A	probably benign	Het
Slfn3	A	T	11: 83,105,427 (GRCm39)	T475S	possibly damaging	Het
Snrnp200	T	A	2: 127,071,085 (GRCm39)	M1122K	possibly damaging	Het
Tead4	T	A	6: 128,219,444 (GRCm39)	K223*	probably null	Het
Tex2	A	C	11: 106,424,776 (GRCm39)	I334R	probably damaging	Het
Tfdp1	C	T	8: 13,420,485 (GRCm39)	R105W	probably damaging	Het
Tfdp1	G	T	8: 13,427,233 (GRCm39)	V393F	possibly damaging	Het
Thsd7b	T	C	1: 129,358,644 (GRCm39)	L26P	probably damaging	Het
Trim80	T	C	11: 115,332,027 (GRCm39)	I73T	probably damaging	Het
Tssk4	T	A	14: 55,887,932 (GRCm39)	Y43N	probably damaging	Het
Ttn	T	C	2: 76,541,839 (GRCm39)	T25389A	probably damaging	Het
Ttn	A	T	2: 76,578,288 (GRCm39)	F24202I	probably damaging	Het
Vmn1r177	A	G	7: 23,565,562 (GRCm39)	S105P	probably damaging	Het
Vmn2r40	T	A	7: 8,911,203 (GRCm39)	T697S	probably benign	Het
Zfp267	T	A	3: 36,219,601 (GRCm39)	C541*	probably null	Het

Other mutations in Igsf10

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00773:Igsf10	APN	3	59,238,960 (GRCm39)	missense	probably benign	0.03
IGL00790:Igsf10	APN	3	59,226,938 (GRCm39)	missense	probably damaging	1.00
IGL00916:Igsf10	APN	3	59,238,548 (GRCm39)	missense	probably damaging	0.97
IGL00928:Igsf10	APN	3	59,238,018 (GRCm39)	missense	probably benign	0.00
IGL01066:Igsf10	APN	3	59,235,203 (GRCm39)	critical splice donor site	probably null
IGL01107:Igsf10	APN	3	59,238,945 (GRCm39)	missense	probably damaging	1.00
IGL01420:Igsf10	APN	3	59,227,071 (GRCm39)	missense	probably benign	0.02
IGL01533:Igsf10	APN	3	59,226,651 (GRCm39)	missense	probably damaging	0.98
IGL01537:Igsf10	APN	3	59,237,452 (GRCm39)	missense	probably benign	0.00
IGL01676:Igsf10	APN	3	59,236,756 (GRCm39)	missense	probably benign	0.17
IGL01676:Igsf10	APN	3	59,233,432 (GRCm39)	missense	probably benign	0.06
IGL01960:Igsf10	APN	3	59,226,158 (GRCm39)	missense	probably benign	0.00
IGL02123:Igsf10	APN	3	59,226,081 (GRCm39)	missense	probably damaging	0.97
IGL02198:Igsf10	APN	3	59,233,399 (GRCm39)	missense	possibly damaging	0.95
IGL02268:Igsf10	APN	3	59,238,573 (GRCm39)	nonsense	probably null
IGL02313:Igsf10	APN	3	59,238,111 (GRCm39)	missense	probably benign	0.01
IGL02368:Igsf10	APN	3	59,235,652 (GRCm39)	missense	probably benign
IGL02494:Igsf10	APN	3	59,235,427 (GRCm39)	missense	probably damaging	0.98
IGL02549:Igsf10	APN	3	59,236,662 (GRCm39)	missense	probably benign	0.03
IGL02616:Igsf10	APN	3	59,226,027 (GRCm39)	missense	probably benign	0.06
IGL02957:Igsf10	APN	3	59,238,285 (GRCm39)	missense	probably damaging	1.00
IGL03067:Igsf10	APN	3	59,226,339 (GRCm39)	missense	probably benign	0.25
IGL03104:Igsf10	APN	3	59,226,905 (GRCm39)	missense	probably damaging	1.00
IGL03124:Igsf10	APN	3	59,227,086 (GRCm39)	missense	probably benign	0.01
IGL03212:Igsf10	APN	3	59,235,586 (GRCm39)	missense	probably benign	0.09
IGL03347:Igsf10	APN	3	59,239,321 (GRCm39)	missense	possibly damaging	0.94
IGL03357:Igsf10	APN	3	59,243,632 (GRCm39)	missense	probably benign	0.35
F6893:Igsf10	UTSW	3	59,238,481 (GRCm39)	missense	probably damaging	1.00
FR4449:Igsf10	UTSW	3	59,226,531 (GRCm39)	missense	probably damaging	1.00
PIT1430001:Igsf10	UTSW	3	59,235,579 (GRCm39)	missense	probably benign	0.06
PIT4402001:Igsf10	UTSW	3	59,233,000 (GRCm39)	missense	probably benign	0.00
PIT4810001:Igsf10	UTSW	3	59,225,903 (GRCm39)	missense	probably damaging	1.00
R0068:Igsf10	UTSW	3	59,238,045 (GRCm39)	missense	probably damaging	0.98
R0095:Igsf10	UTSW	3	59,238,617 (GRCm39)	nonsense	probably null
R0095:Igsf10	UTSW	3	59,238,617 (GRCm39)	nonsense	probably null
R0112:Igsf10	UTSW	3	59,233,429 (GRCm39)	missense	probably benign	0.00
R0141:Igsf10	UTSW	3	59,238,253 (GRCm39)	missense	probably damaging	1.00
R0538:Igsf10	UTSW	3	59,227,527 (GRCm39)	missense	probably damaging	0.99
R0551:Igsf10	UTSW	3	59,236,089 (GRCm39)	missense	probably benign	0.01
R0556:Igsf10	UTSW	3	59,236,296 (GRCm39)	missense	probably benign	0.02
R0582:Igsf10	UTSW	3	59,227,188 (GRCm39)	missense	probably benign	0.00
R0630:Igsf10	UTSW	3	59,233,483 (GRCm39)	missense	probably damaging	1.00
R0675:Igsf10	UTSW	3	59,236,015 (GRCm39)	missense	probably benign	0.14
R0948:Igsf10	UTSW	3	59,238,525 (GRCm39)	missense	probably damaging	1.00
R1252:Igsf10	UTSW	3	59,239,269 (GRCm39)	missense	probably benign	0.03
R1412:Igsf10	UTSW	3	59,235,196 (GRCm39)	splice site	probably benign
R1473:Igsf10	UTSW	3	59,226,188 (GRCm39)	missense	probably damaging	1.00
R1585:Igsf10	UTSW	3	59,237,838 (GRCm39)	missense	probably damaging	1.00
R1650:Igsf10	UTSW	3	59,233,583 (GRCm39)	missense	probably damaging	1.00
R1660:Igsf10	UTSW	3	59,238,706 (GRCm39)	missense	probably damaging	1.00
R1671:Igsf10	UTSW	3	59,235,921 (GRCm39)	nonsense	probably null
R1748:Igsf10	UTSW	3	59,226,514 (GRCm39)	missense	probably damaging	1.00
R1758:Igsf10	UTSW	3	59,236,617 (GRCm39)	missense	probably benign	0.09
R1856:Igsf10	UTSW	3	59,238,693 (GRCm39)	missense	possibly damaging	0.63
R1912:Igsf10	UTSW	3	59,236,993 (GRCm39)	missense	probably benign	0.40
R2148:Igsf10	UTSW	3	59,243,998 (GRCm39)	missense	possibly damaging	0.77
R2155:Igsf10	UTSW	3	59,239,101 (GRCm39)	missense	probably damaging	1.00
R2509:Igsf10	UTSW	3	59,239,287 (GRCm39)	missense	probably damaging	1.00
R2511:Igsf10	UTSW	3	59,239,287 (GRCm39)	missense	probably damaging	1.00
R2680:Igsf10	UTSW	3	59,232,875 (GRCm39)	missense	probably benign	0.14
R2913:Igsf10	UTSW	3	59,239,157 (GRCm39)	missense	possibly damaging	0.70
R2927:Igsf10	UTSW	3	59,236,848 (GRCm39)	missense	probably benign
R3547:Igsf10	UTSW	3	59,243,935 (GRCm39)	missense	probably damaging	1.00
R3547:Igsf10	UTSW	3	59,237,962 (GRCm39)	missense	probably benign	0.02
R3548:Igsf10	UTSW	3	59,243,935 (GRCm39)	missense	probably damaging	1.00
R3620:Igsf10	UTSW	3	59,243,752 (GRCm39)	missense	probably damaging	1.00
R3732:Igsf10	UTSW	3	59,233,135 (GRCm39)	missense	probably benign	0.29
R3743:Igsf10	UTSW	3	59,233,546 (GRCm39)	missense	possibly damaging	0.69
R3973:Igsf10	UTSW	3	59,239,345 (GRCm39)	missense	probably damaging	1.00
R4005:Igsf10	UTSW	3	59,235,981 (GRCm39)	missense	probably benign	0.00
R4184:Igsf10	UTSW	3	59,227,152 (GRCm39)	missense	probably damaging	1.00
R4302:Igsf10	UTSW	3	59,226,171 (GRCm39)	missense	probably damaging	1.00
R4404:Igsf10	UTSW	3	59,236,972 (GRCm39)	missense	probably benign	0.04
R4575:Igsf10	UTSW	3	59,237,521 (GRCm39)	missense	probably benign
R4676:Igsf10	UTSW	3	59,233,370 (GRCm39)	missense	probably benign	0.23
R4700:Igsf10	UTSW	3	59,227,751 (GRCm39)	missense	probably damaging	0.99
R4765:Igsf10	UTSW	3	59,237,126 (GRCm39)	missense	probably benign	0.01
R4986:Igsf10	UTSW	3	59,236,027 (GRCm39)	missense	probably benign	0.24
R5012:Igsf10	UTSW	3	59,226,143 (GRCm39)	missense	probably damaging	1.00
R5070:Igsf10	UTSW	3	59,235,714 (GRCm39)	missense	probably benign	0.02
R5083:Igsf10	UTSW	3	59,233,694 (GRCm39)	missense	probably damaging	1.00
R5336:Igsf10	UTSW	3	59,227,553 (GRCm39)	missense	probably damaging	1.00
R5462:Igsf10	UTSW	3	59,233,175 (GRCm39)	missense	probably damaging	1.00
R5648:Igsf10	UTSW	3	59,235,574 (GRCm39)	missense	probably benign	0.01
R5810:Igsf10	UTSW	3	59,226,492 (GRCm39)	missense	probably damaging	1.00
R5871:Igsf10	UTSW	3	59,237,832 (GRCm39)	missense	possibly damaging	0.83
R5880:Igsf10	UTSW	3	59,238,252 (GRCm39)	missense	probably damaging	1.00
R5935:Igsf10	UTSW	3	59,235,578 (GRCm39)	missense	probably benign	0.12
R5979:Igsf10	UTSW	3	59,243,894 (GRCm39)	missense	probably damaging	1.00
R6145:Igsf10	UTSW	3	59,239,077 (GRCm39)	missense	possibly damaging	0.83
R6222:Igsf10	UTSW	3	59,226,336 (GRCm39)	missense	possibly damaging	0.90
R6224:Igsf10	UTSW	3	59,232,931 (GRCm39)	missense	probably damaging	1.00
R6264:Igsf10	UTSW	3	59,235,928 (GRCm39)	missense	possibly damaging	0.88
R6283:Igsf10	UTSW	3	59,226,870 (GRCm39)	missense	probably damaging	1.00
R6336:Igsf10	UTSW	3	59,237,760 (GRCm39)	missense	probably benign	0.00
R6490:Igsf10	UTSW	3	59,236,992 (GRCm39)	missense	probably benign	0.06
R6873:Igsf10	UTSW	3	59,235,865 (GRCm39)	missense	probably benign
R6889:Igsf10	UTSW	3	59,239,354 (GRCm39)	missense	probably benign
R7024:Igsf10	UTSW	3	59,239,122 (GRCm39)	missense	probably benign	0.00
R7056:Igsf10	UTSW	3	59,238,501 (GRCm39)	missense	probably damaging	1.00
R7128:Igsf10	UTSW	3	59,236,326 (GRCm39)	missense	probably benign
R7251:Igsf10	UTSW	3	59,226,875 (GRCm39)	missense	probably damaging	1.00
R7313:Igsf10	UTSW	3	59,236,837 (GRCm39)	missense	probably benign	0.05
R7340:Igsf10	UTSW	3	59,233,189 (GRCm39)	missense	probably damaging	1.00
R7447:Igsf10	UTSW	3	59,239,222 (GRCm39)	missense	probably benign	0.39
R7506:Igsf10	UTSW	3	59,226,775 (GRCm39)	missense	probably damaging	1.00
R7678:Igsf10	UTSW	3	59,226,761 (GRCm39)	missense	possibly damaging	0.81
R7695:Igsf10	UTSW	3	59,233,612 (GRCm39)	missense	probably damaging	1.00
R7709:Igsf10	UTSW	3	59,238,964 (GRCm39)	missense	probably damaging	0.96
R7749:Igsf10	UTSW	3	59,236,549 (GRCm39)	missense	possibly damaging	0.88
R7808:Igsf10	UTSW	3	59,235,489 (GRCm39)	missense	probably benign	0.00
R7850:Igsf10	UTSW	3	59,227,053 (GRCm39)	missense	probably benign	0.33
R7879:Igsf10	UTSW	3	59,238,145 (GRCm39)	missense	probably damaging	1.00
R7886:Igsf10	UTSW	3	59,235,748 (GRCm39)	missense	probably benign	0.01
R7891:Igsf10	UTSW	3	59,235,832 (GRCm39)	nonsense	probably null
R7946:Igsf10	UTSW	3	59,227,125 (GRCm39)	missense	possibly damaging	0.69
R7948:Igsf10	UTSW	3	59,239,279 (GRCm39)	missense	probably benign	0.02
R8004:Igsf10	UTSW	3	59,237,130 (GRCm39)	missense	probably benign	0.01
R8096:Igsf10	UTSW	3	59,236,380 (GRCm39)	missense	probably damaging	0.98
R8141:Igsf10	UTSW	3	59,237,949 (GRCm39)	missense	probably damaging	0.96
R8183:Igsf10	UTSW	3	59,238,036 (GRCm39)	missense	probably benign	0.04
R8203:Igsf10	UTSW	3	59,236,254 (GRCm39)	missense	probably benign	0.11
R8325:Igsf10	UTSW	3	59,225,954 (GRCm39)	missense	probably damaging	0.96
R8350:Igsf10	UTSW	3	59,238,949 (GRCm39)	missense	probably damaging	1.00
R8387:Igsf10	UTSW	3	59,236,564 (GRCm39)	missense	probably damaging	1.00
R8488:Igsf10	UTSW	3	59,227,431 (GRCm39)	missense	probably damaging	1.00
R8697:Igsf10	UTSW	3	59,226,308 (GRCm39)	missense	probably benign	0.02
R8786:Igsf10	UTSW	3	59,238,063 (GRCm39)	missense	probably benign	0.25
R8804:Igsf10	UTSW	3	59,243,876 (GRCm39)	missense	probably damaging	1.00
R8886:Igsf10	UTSW	3	59,237,410 (GRCm39)	missense	probably benign	0.00
R8902:Igsf10	UTSW	3	59,243,633 (GRCm39)	missense	probably benign	0.00
R8906:Igsf10	UTSW	3	59,233,739 (GRCm39)	missense	probably benign	0.01
R8917:Igsf10	UTSW	3	59,226,888 (GRCm39)	missense	possibly damaging	0.69
R9051:Igsf10	UTSW	3	59,236,668 (GRCm39)	missense	probably benign	0.00
R9178:Igsf10	UTSW	3	59,233,480 (GRCm39)	missense	possibly damaging	0.69
R9228:Igsf10	UTSW	3	59,243,843 (GRCm39)	missense	probably damaging	1.00
R9230:Igsf10	UTSW	3	59,243,843 (GRCm39)	missense	probably damaging	1.00
R9231:Igsf10	UTSW	3	59,243,843 (GRCm39)	missense	probably damaging	1.00
R9232:Igsf10	UTSW	3	59,243,843 (GRCm39)	missense	probably damaging	1.00
R9417:Igsf10	UTSW	3	59,236,526 (GRCm39)	missense	possibly damaging	0.94
R9609:Igsf10	UTSW	3	59,226,869 (GRCm39)	missense	probably damaging	1.00
R9631:Igsf10	UTSW	3	59,237,904 (GRCm39)	missense	probably damaging	1.00
R9689:Igsf10	UTSW	3	59,233,624 (GRCm39)	missense	probably damaging	1.00
R9762:Igsf10	UTSW	3	59,237,106 (GRCm39)	missense	probably damaging	1.00
R9770:Igsf10	UTSW	3	59,227,199 (GRCm39)	missense	probably benign	0.07
R9798:Igsf10	UTSW	3	59,239,126 (GRCm39)	missense	probably damaging	1.00
Z1088:Igsf10	UTSW	3	59,237,359 (GRCm39)	missense	possibly damaging	0.59
Z1177:Igsf10	UTSW	3	59,237,026 (GRCm39)	nonsense	probably null

Predicted Primers

PCR Primer
(F):5'- CCCGGTTCGTATGTCAGAATG -3'
(R):5'- ATTCTGCGGATTTCACCTGTG -3'

Sequencing Primer
(F):5'- AACAGGATGAGTTTCTCGATGTAGCC -3'
(R):5'- CTGTGTGGTTCGGAGCGAAG -3'

Posted On

2018-08-29