Incidental Mutation 'IGL01121:Gm15097'
ID53341
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Gm15097
Ensembl Gene ENSMUSG00000094378
Gene Namepredicted gene 15097
Synonyms
Accession Numbers
Is this an essential gene? Not available question?
Stock #IGL01121
Quality Score
Status
ChromosomeX
Chromosomal Location149784473-149826694 bp(+) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) A to T at 149804328 bp
ZygosityHeterozygous
Amino Acid Change Arginine to Serine at position 129 (R129S)
Ref Sequence ENSEMBL: ENSMUSP00000108361 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000101180] [ENSMUST00000112741]
Predicted Effect possibly damaging
Transcript: ENSMUST00000101180
AA Change: R129S

PolyPhen 2 Score 0.663 (Sensitivity: 0.86; Specificity: 0.91)
SMART Domains Protein: ENSMUSP00000098740
Gene: ENSMUSG00000094378
AA Change: R129S

DomainStartEndE-ValueType
low complexity region 15 27 N/A INTRINSIC
low complexity region 42 59 N/A INTRINSIC
low complexity region 90 106 N/A INTRINSIC
low complexity region 117 136 N/A INTRINSIC
internal_repeat_1 140 230 3.08e-5 PROSPERO
low complexity region 247 261 N/A INTRINSIC
internal_repeat_1 266 349 3.08e-5 PROSPERO
Predicted Effect possibly damaging
Transcript: ENSMUST00000112741
AA Change: R129S

PolyPhen 2 Score 0.663 (Sensitivity: 0.86; Specificity: 0.91)
SMART Domains Protein: ENSMUSP00000108361
Gene: ENSMUSG00000094378
AA Change: R129S

DomainStartEndE-ValueType
low complexity region 15 27 N/A INTRINSIC
low complexity region 42 59 N/A INTRINSIC
low complexity region 90 106 N/A INTRINSIC
low complexity region 117 136 N/A INTRINSIC
internal_repeat_1 140 230 3.08e-5 PROSPERO
low complexity region 247 261 N/A INTRINSIC
internal_repeat_1 266 349 3.08e-5 PROSPERO
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 42 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
2700046A07Rik G A 18: 62,755,148 noncoding transcript Het
4930432E11Rik A T 7: 29,574,001 noncoding transcript Het
Alg3 T C 16: 20,610,647 E31G probably damaging Het
Arhgap29 A G 3: 122,009,863 E764G probably damaging Het
Atp5j2 C A 5: 145,184,568 V68L probably benign Het
Birc6 T A 17: 74,631,038 I2645K probably benign Het
Capn11 A G 17: 45,639,132 S369P probably benign Het
Car4 A T 11: 84,964,346 probably null Het
Ccdc185 C T 1: 182,748,657 V156I probably benign Het
Cpsf2 G T 12: 101,988,706 E245D probably damaging Het
Dnah11 T C 12: 118,050,695 D2019G probably benign Het
Dscc1 A G 15: 55,082,325 probably benign Het
Dzip3 T C 16: 48,944,881 D490G probably benign Het
E2f8 G A 7: 48,867,821 Q745* probably null Het
Fat3 T A 9: 15,998,401 T2102S probably benign Het
Fgf7 C T 2: 126,088,232 probably benign Het
Fstl4 T C 11: 52,814,637 F47L probably benign Het
Gm4297 C T X: 24,552,615 D200N probably benign Het
Itgb5 G T 16: 33,919,989 D490Y probably benign Het
Kansl1 A G 11: 104,335,596 S912P probably benign Het
Kcnq3 A T 15: 66,005,977 probably benign Het
Kctd6 A G 14: 8,222,656 H166R possibly damaging Het
Kel T C 6: 41,702,409 D140G probably benign Het
Lrif1 C A 3: 106,735,664 S177* probably null Het
Lrp1 A T 10: 127,583,853 C962* probably null Het
Lypd5 A T 7: 24,351,551 Y29F probably benign Het
Mmrn1 A G 6: 60,975,944 D403G possibly damaging Het
Nhsl1 T G 10: 18,511,710 V244G probably damaging Het
Olfr781 T C 10: 129,332,935 I18T probably benign Het
Ptprd A T 4: 75,954,201 probably benign Het
Rcan2 A T 17: 44,017,884 I69L probably damaging Het
Rprd2 A G 3: 95,776,550 L373P probably damaging Het
Slc10a4 T C 5: 73,007,586 C174R probably damaging Het
Tas2r134 C T 2: 51,627,989 T160I probably damaging Het
Tbc1d19 T A 5: 53,897,062 L464* probably null Het
Tmem45a2 C T 16: 57,040,790 D225N possibly damaging Het
Unc79 G A 12: 103,165,631 C2139Y probably damaging Het
Vmn2r101 G T 17: 19,589,674 G241C probably damaging Het
Vmn2r91 T C 17: 18,136,504 V811A possibly damaging Het
Wdr11 T C 7: 129,628,022 Y844H probably benign Het
Wdr70 T C 15: 7,873,174 K656E possibly damaging Het
Zfp579 C A 7: 4,993,247 C555F possibly damaging Het
Posted On2013-06-21