Incidental Mutation 'IGL01023:Gm14406'
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Gm14406
Ensembl Gene ENSMUSG00000078865
Gene Namepredicted gene 14406
Accession Numbers
Is this an essential gene? Not available question?
Stock #IGL01023
Quality Score
Chromosomal Location177569204-177578210 bp(-) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) A to T at 177569239 bp
Amino Acid Change Cysteine to Serine at position 416 (C416S)
Ref Sequence ENSEMBL: ENSMUSP00000104573 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000108943] [ENSMUST00000108945]
Predicted Effect probably benign
Transcript: ENSMUST00000108943
SMART Domains Protein: ENSMUSP00000104571
Gene: ENSMUSG00000078865

KRAB 4 64 1.1e-11 SMART
Predicted Effect probably damaging
Transcript: ENSMUST00000108945
AA Change: C416S

PolyPhen 2 Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)
SMART Domains Protein: ENSMUSP00000104573
Gene: ENSMUSG00000078865
AA Change: C416S

KRAB 4 66 1.47e-12 SMART
ZnF_C2H2 78 97 2.2e2 SMART
ZnF_C2H2 103 125 7.78e-3 SMART
ZnF_C2H2 131 153 2.12e-4 SMART
ZnF_C2H2 159 181 2.43e-4 SMART
ZnF_C2H2 187 209 2.53e-2 SMART
ZnF_C2H2 215 237 4.87e-4 SMART
ZnF_C2H2 243 265 1.12e-3 SMART
ZnF_C2H2 271 293 4.54e-4 SMART
ZnF_C2H2 299 321 3.04e-5 SMART
ZnF_C2H2 327 349 4.87e-4 SMART
ZnF_C2H2 355 377 1.03e-2 SMART
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 32 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Anapc1 A G 2: 128,629,729 L1472P probably damaging Het
BC005561 T A 5: 104,520,500 W963R probably damaging Het
Col18a1 C T 10: 77,070,975 V1151M probably damaging Het
Crmp1 A T 5: 37,276,313 D286V probably damaging Het
Ddx60 A T 8: 61,942,514 I162F probably damaging Het
Fam24b A T 7: 131,326,174 C95* probably null Het
Fsd1 A G 17: 55,988,245 Y78C probably damaging Het
Galc C T 12: 98,231,422 V343I probably benign Het
Glis2 C T 16: 4,611,650 R214C probably damaging Het
Gm5724 A G 6: 141,754,429 S126P probably benign Het
Gnat3 T C 5: 18,003,828 S177P probably damaging Het
Higd1a C T 9: 121,849,683 G80D possibly damaging Het
Hp1bp3 T C 4: 138,240,629 V421A possibly damaging Het
Ipo11 A T 13: 106,897,259 F238L probably benign Het
Med26 A T 8: 72,495,874 F460L possibly damaging Het
Olfr1111 T A 2: 87,149,825 T279S possibly damaging Het
Osbp2 T C 11: 3,863,387 I161V probably benign Het
Prr5 T C 15: 84,699,655 V152A possibly damaging Het
Prx T A 7: 27,519,419 I1115K probably benign Het
Ptpn22 A G 3: 103,903,374 I708M probably benign Het
Robo3 T C 9: 37,429,551 T120A probably damaging Het
Setd2 C A 9: 110,547,513 S132* probably null Het
Slc9a1 A G 4: 133,422,143 E760G probably benign Het
Stx16 A T 2: 174,092,409 H135L probably damaging Het
Tas2r131 A T 6: 132,957,801 L15Q probably damaging Het
Tmcc1 A G 6: 116,043,027 L128P probably damaging Het
Tmem269 C A 4: 119,209,314 M182I probably benign Het
Tnfaip8l2 A G 3: 95,140,415 S46P probably damaging Het
Trim30c A G 7: 104,382,972 probably benign Het
Unc13a C T 8: 71,661,825 E184K probably benign Het
Wfs1 A T 5: 36,967,917 C467* probably null Het
Zfp78 G A 7: 6,375,588 G77D possibly damaging Het
Other mutations in Gm14406
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL02382:Gm14406 APN 2 177569195 unclassified probably benign
Posted On2013-06-28