Incidental Mutation 'R6861:Gcn1'
| ID |
535512 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Gcn1
|
| Ensembl Gene |
ENSMUSG00000041638 |
| Gene Name |
GCN1 activator of EIF2AK4 |
| Synonyms |
Gcn1l1, G431004K08Rik, GCN1L |
| MMRRC Submission |
044962-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably essential
(E-score: 0.939)
|
| Stock # |
R6861 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
5 |
| Chromosomal Location |
115703313-115760713 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 115749108 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Aspartic acid to Glycine
at position 1880
(D1880G)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000069432
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000064454]
|
| AlphaFold |
E9PVA8 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000064454
AA Change: D1880G
PolyPhen 2
Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
|
| SMART Domains |
Protein: ENSMUSP00000069432
Gene: ENSMUSG00000041638
AA Change: D1880G
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
64 |
84 |
N/A |
INTRINSIC |
|
low complexity region
|
108 |
117 |
N/A |
INTRINSIC |
|
low complexity region
|
142 |
154 |
N/A |
INTRINSIC |
|
Pfam:DUF3554
|
357 |
705 |
2e-61 |
PFAM |
|
coiled coil region
|
806 |
866 |
N/A |
INTRINSIC |
|
Blast:ARM
|
1028 |
1068 |
6e-11 |
BLAST |
|
coiled coil region
|
1180 |
1203 |
N/A |
INTRINSIC |
|
low complexity region
|
1457 |
1466 |
N/A |
INTRINSIC |
|
low complexity region
|
1501 |
1510 |
N/A |
INTRINSIC |
|
ARM
|
1527 |
1567 |
3.69e1 |
SMART |
|
Blast:ARM
|
1602 |
1644 |
1e-5 |
BLAST |
|
Blast:EZ_HEAT
|
1671 |
1704 |
1e-7 |
BLAST |
|
low complexity region
|
1926 |
1934 |
N/A |
INTRINSIC |
|
low complexity region
|
1956 |
1972 |
N/A |
INTRINSIC |
|
ARM
|
2034 |
2070 |
9.27e1 |
SMART |
|
low complexity region
|
2326 |
2334 |
N/A |
INTRINSIC |
|
ARM
|
2416 |
2455 |
2.16e1 |
SMART |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.6%
- 20x: 98.6%
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 86 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Adamtsl4 |
G |
A |
3: 95,588,194 (GRCm39) |
R598C |
probably damaging |
Het |
| Adra2a |
T |
C |
19: 54,034,818 (GRCm39) |
L58P |
probably damaging |
Het |
| Ajm1 |
C |
CTCTA |
2: 25,469,733 (GRCm39) |
|
probably null |
Het |
| Alox5ap |
A |
G |
5: 149,201,927 (GRCm39) |
D2G |
probably damaging |
Het |
| Arid1b |
G |
A |
17: 5,377,961 (GRCm39) |
V1238M |
possibly damaging |
Het |
| Bank1 |
A |
G |
3: 135,960,764 (GRCm39) |
V31A |
probably benign |
Het |
| Bptf |
G |
A |
11: 106,953,391 (GRCm39) |
T2117M |
probably damaging |
Het |
| Cadps |
G |
A |
14: 12,522,401 (GRCm38) |
R588* |
probably null |
Het |
| Cavin4 |
A |
G |
4: 48,672,214 (GRCm39) |
I220V |
probably benign |
Het |
| Cep192 |
G |
A |
18: 67,974,699 (GRCm39) |
M1267I |
probably benign |
Het |
| Cers5 |
G |
A |
15: 99,670,244 (GRCm39) |
|
probably benign |
Het |
| Cfap65 |
A |
T |
1: 74,964,274 (GRCm39) |
I558N |
probably damaging |
Het |
| Cfh |
A |
T |
1: 140,028,621 (GRCm39) |
S1025T |
probably benign |
Het |
| Cftr |
A |
G |
6: 18,268,107 (GRCm39) |
I689V |
probably benign |
Het |
| Cgrrf1 |
T |
C |
14: 47,069,785 (GRCm39) |
I18T |
probably damaging |
Het |
| CK137956 |
A |
G |
4: 127,864,519 (GRCm39) |
S37P |
probably damaging |
Het |
| Clca4a |
T |
C |
3: 144,676,416 (GRCm39) |
D88G |
probably benign |
Het |
| Col11a1 |
G |
A |
3: 113,961,141 (GRCm39) |
G1166D |
probably damaging |
Het |
| Col24a1 |
G |
A |
3: 145,166,589 (GRCm39) |
G1075S |
probably damaging |
Het |
| Crispld2 |
C |
T |
8: 120,752,852 (GRCm39) |
T299M |
probably damaging |
Het |
| Cyb561a3 |
T |
A |
19: 10,562,701 (GRCm39) |
Y114N |
probably damaging |
Het |
| Cyp3a57 |
T |
A |
5: 145,307,773 (GRCm39) |
W147R |
possibly damaging |
Het |
| Dnah2 |
C |
A |
11: 69,346,789 (GRCm39) |
R2599L |
possibly damaging |
Het |
| Dock1 |
T |
A |
7: 134,373,207 (GRCm39) |
S525T |
probably benign |
Het |
| Drc7 |
T |
G |
8: 95,789,025 (GRCm39) |
|
probably null |
Het |
| Efhd2 |
G |
T |
4: 141,587,192 (GRCm39) |
|
probably null |
Het |
| Epb41l1 |
A |
T |
2: 156,367,142 (GRCm39) |
E658D |
probably benign |
Het |
| Evi5 |
C |
T |
5: 107,896,184 (GRCm39) |
S753N |
probably benign |
Het |
| Exoc3 |
A |
T |
13: 74,337,319 (GRCm39) |
D427E |
probably benign |
Het |
| Fbxw9 |
A |
G |
8: 85,792,740 (GRCm39) |
D363G |
probably damaging |
Het |
| Fcer2a |
T |
C |
8: 3,732,910 (GRCm39) |
Y277C |
probably damaging |
Het |
| Fstl5 |
A |
T |
3: 76,229,523 (GRCm39) |
Y108F |
probably damaging |
Het |
| Gm4924 |
T |
A |
10: 82,214,948 (GRCm39) |
Y915* |
probably null |
Het |
| Gpr139 |
T |
A |
7: 118,743,875 (GRCm39) |
I237F |
probably benign |
Het |
| Hao2 |
A |
G |
3: 98,784,498 (GRCm39) |
L289S |
probably damaging |
Het |
| Hexim1 |
A |
G |
11: 103,007,793 (GRCm39) |
S16G |
probably benign |
Het |
| Hmgcs1 |
T |
A |
13: 120,161,535 (GRCm39) |
M109K |
probably damaging |
Het |
| Hs3st4 |
T |
A |
7: 123,996,052 (GRCm39) |
N239K |
possibly damaging |
Het |
| Hsd3b5 |
T |
A |
3: 98,529,328 (GRCm39) |
N101Y |
probably damaging |
Het |
| Idh2 |
G |
A |
7: 79,747,966 (GRCm39) |
P245S |
probably damaging |
Het |
| Irx3 |
A |
G |
8: 92,525,530 (GRCm39) |
|
probably benign |
Het |
| Lilra5 |
A |
T |
7: 4,244,931 (GRCm39) |
D234V |
probably benign |
Het |
| Lrfn5 |
G |
A |
12: 61,886,476 (GRCm39) |
S88N |
probably damaging |
Het |
| Lrp2 |
A |
T |
2: 69,343,721 (GRCm39) |
S879R |
possibly damaging |
Het |
| Lsm11 |
A |
G |
11: 45,824,781 (GRCm39) |
S249P |
probably benign |
Het |
| Ltbp1 |
C |
T |
17: 75,534,187 (GRCm39) |
A543V |
possibly damaging |
Het |
| Mbd1 |
GTCTGCATCTGCGTCTTCGTCTGCATCTGCATCTGCGTCTTCGTCTGCATCTGCATCTGC |
GTCTGCATCTGCGTCTTCGTCTGCATCTGCATCTGC |
18: 74,406,645 (GRCm39) |
|
|
Het |
| Mier2 |
C |
T |
10: 79,376,990 (GRCm39) |
|
probably benign |
Het |
| Mup6 |
G |
C |
4: 60,004,093 (GRCm39) |
G70A |
probably benign |
Het |
| Neb |
A |
G |
2: 52,085,732 (GRCm39) |
L5258P |
probably damaging |
Het |
| Nlrc5 |
G |
A |
8: 95,247,857 (GRCm39) |
|
probably benign |
Het |
| Nr6a1 |
A |
T |
2: 38,630,597 (GRCm39) |
F207I |
possibly damaging |
Het |
| Or2y1 |
A |
T |
11: 49,385,632 (GRCm39) |
T91S |
probably benign |
Het |
| Or5k17 |
A |
T |
16: 58,746,867 (GRCm39) |
D22E |
probably benign |
Het |
| Or8b43 |
T |
C |
9: 38,360,731 (GRCm39) |
C188R |
probably damaging |
Het |
| Osbp2 |
A |
G |
11: 3,665,191 (GRCm39) |
V51A |
possibly damaging |
Het |
| Papln |
G |
T |
12: 83,821,723 (GRCm39) |
C317F |
probably damaging |
Het |
| Pdcd7 |
T |
C |
9: 65,265,904 (GRCm39) |
S454P |
probably damaging |
Het |
| Pde4a |
C |
T |
9: 21,116,597 (GRCm39) |
T473I |
probably damaging |
Het |
| Peg10 |
CC |
CCCCATCAGGC |
6: 4,756,350 (GRCm39) |
|
probably benign |
Het |
| Peg10 |
C |
CCCATCAGGA |
6: 4,756,351 (GRCm39) |
|
probably benign |
Het |
| Peg3 |
G |
T |
7: 6,714,385 (GRCm39) |
S279* |
probably null |
Het |
| Rbl1 |
A |
G |
2: 156,994,887 (GRCm39) |
Y929H |
probably damaging |
Het |
| Rsf1 |
G |
GACGGCGGCA |
7: 97,229,116 (GRCm39) |
|
probably benign |
Het |
| Sall3 |
C |
A |
18: 81,017,590 (GRCm39) |
E113* |
probably null |
Het |
| Scn5a |
A |
C |
9: 119,359,089 (GRCm39) |
F653V |
probably damaging |
Het |
| Selenok |
T |
A |
14: 29,692,005 (GRCm39) |
N14K |
possibly damaging |
Het |
| Slc22a20 |
T |
C |
19: 6,021,838 (GRCm39) |
T426A |
probably benign |
Het |
| Slc4a2 |
T |
A |
5: 24,640,007 (GRCm39) |
S563T |
probably damaging |
Het |
| Sspo |
T |
A |
6: 48,464,889 (GRCm39) |
S3798T |
probably benign |
Het |
| Stag3 |
G |
T |
5: 138,302,969 (GRCm39) |
R63L |
possibly damaging |
Het |
| Stard9 |
A |
T |
2: 120,535,667 (GRCm39) |
M3975L |
probably benign |
Het |
| Syne2 |
C |
A |
12: 75,956,040 (GRCm39) |
T582K |
probably damaging |
Het |
| Synj1 |
G |
A |
16: 90,760,768 (GRCm39) |
Q748* |
probably null |
Het |
| Tas2r109 |
T |
C |
6: 132,957,048 (GRCm39) |
D294G |
probably benign |
Het |
| Tbl1xr1 |
C |
T |
3: 22,245,603 (GRCm39) |
T203M |
possibly damaging |
Het |
| Tbl1xr1 |
T |
A |
3: 22,245,703 (GRCm39) |
|
probably null |
Het |
| Tcf7l2 |
A |
G |
19: 55,730,955 (GRCm39) |
D19G |
probably damaging |
Het |
| Tecta |
A |
G |
9: 42,248,633 (GRCm39) |
V1923A |
possibly damaging |
Het |
| Tg |
T |
A |
15: 66,560,740 (GRCm39) |
M1034K |
probably benign |
Het |
| Ttf2 |
T |
C |
3: 100,876,941 (GRCm39) |
E8G |
possibly damaging |
Het |
| Vps13b |
T |
A |
15: 35,576,541 (GRCm39) |
V983E |
probably damaging |
Het |
| Vps35l |
A |
G |
7: 118,342,898 (GRCm39) |
H32R |
probably damaging |
Het |
| Vwa2 |
T |
C |
19: 56,890,025 (GRCm39) |
V210A |
probably benign |
Het |
| Xkr6 |
T |
A |
14: 64,057,093 (GRCm39) |
Y335N |
probably benign |
Het |
| Zfp97 |
A |
G |
17: 17,365,437 (GRCm39) |
H312R |
probably damaging |
Het |
|
| Other mutations in Gcn1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00869:Gcn1
|
APN |
5 |
115,726,202 (GRCm39) |
splice site |
probably benign |
|
|
IGL00974:Gcn1
|
APN |
5 |
115,751,852 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
IGL01566:Gcn1
|
APN |
5 |
115,749,117 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01843:Gcn1
|
APN |
5 |
115,757,759 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01885:Gcn1
|
APN |
5 |
115,714,174 (GRCm39) |
splice site |
probably null |
|
|
IGL02081:Gcn1
|
APN |
5 |
115,723,930 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02118:Gcn1
|
APN |
5 |
115,748,938 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02150:Gcn1
|
APN |
5 |
115,747,927 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02190:Gcn1
|
APN |
5 |
115,752,183 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02219:Gcn1
|
APN |
5 |
115,751,826 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
IGL02507:Gcn1
|
APN |
5 |
115,723,940 (GRCm39) |
missense |
probably benign |
0.11 |
|
IGL02644:Gcn1
|
APN |
5 |
115,713,250 (GRCm39) |
missense |
probably benign |
|
|
IGL02678:Gcn1
|
APN |
5 |
115,751,814 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02748:Gcn1
|
APN |
5 |
115,748,859 (GRCm39) |
splice site |
probably null |
|
|
IGL02755:Gcn1
|
APN |
5 |
115,742,065 (GRCm39) |
splice site |
probably null |
|
|
IGL02896:Gcn1
|
APN |
5 |
115,757,707 (GRCm39) |
splice site |
probably benign |
|
|
cusp
|
UTSW |
5 |
115,749,119 (GRCm39) |
missense |
probably damaging |
1.00 |
|
farthing
|
UTSW |
5 |
115,714,167 (GRCm39) |
splice site |
probably benign |
|
|
IGL03147:Gcn1
|
UTSW |
5 |
115,748,917 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R0362:Gcn1
|
UTSW |
5 |
115,714,167 (GRCm39) |
splice site |
probably benign |
|
|
R0540:Gcn1
|
UTSW |
5 |
115,727,015 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0569:Gcn1
|
UTSW |
5 |
115,733,118 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0570:Gcn1
|
UTSW |
5 |
115,730,480 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0584:Gcn1
|
UTSW |
5 |
115,733,074 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0630:Gcn1
|
UTSW |
5 |
115,719,148 (GRCm39) |
missense |
probably benign |
0.06 |
|
R0656:Gcn1
|
UTSW |
5 |
115,727,362 (GRCm39) |
missense |
probably benign |
0.27 |
|
R0801:Gcn1
|
UTSW |
5 |
115,729,065 (GRCm39) |
missense |
probably benign |
0.12 |
|
R0890:Gcn1
|
UTSW |
5 |
115,717,852 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R1400:Gcn1
|
UTSW |
5 |
115,752,220 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1485:Gcn1
|
UTSW |
5 |
115,712,676 (GRCm39) |
missense |
probably benign |
|
|
R1574:Gcn1
|
UTSW |
5 |
115,753,611 (GRCm39) |
missense |
probably benign |
|
|
R1574:Gcn1
|
UTSW |
5 |
115,753,611 (GRCm39) |
missense |
probably benign |
|
|
R1673:Gcn1
|
UTSW |
5 |
115,720,356 (GRCm39) |
missense |
probably benign |
|
|
R1894:Gcn1
|
UTSW |
5 |
115,727,174 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2114:Gcn1
|
UTSW |
5 |
115,736,884 (GRCm39) |
missense |
probably benign |
0.35 |
|
R2116:Gcn1
|
UTSW |
5 |
115,736,884 (GRCm39) |
missense |
probably benign |
0.35 |
|
R2117:Gcn1
|
UTSW |
5 |
115,736,884 (GRCm39) |
missense |
probably benign |
0.35 |
|
R2152:Gcn1
|
UTSW |
5 |
115,747,888 (GRCm39) |
missense |
probably benign |
0.07 |
|
R2162:Gcn1
|
UTSW |
5 |
115,730,191 (GRCm39) |
missense |
probably benign |
0.18 |
|
R2216:Gcn1
|
UTSW |
5 |
115,731,720 (GRCm39) |
missense |
probably benign |
|
|
R2218:Gcn1
|
UTSW |
5 |
115,757,720 (GRCm39) |
missense |
probably benign |
0.04 |
|
R2278:Gcn1
|
UTSW |
5 |
115,749,234 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2280:Gcn1
|
UTSW |
5 |
115,750,789 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3719:Gcn1
|
UTSW |
5 |
115,717,876 (GRCm39) |
missense |
probably benign |
0.03 |
|
R3729:Gcn1
|
UTSW |
5 |
115,721,453 (GRCm39) |
splice site |
probably benign |
|
|
R3833:Gcn1
|
UTSW |
5 |
115,730,191 (GRCm39) |
missense |
probably benign |
0.18 |
|
R3932:Gcn1
|
UTSW |
5 |
115,725,893 (GRCm39) |
missense |
probably benign |
0.11 |
|
R4067:Gcn1
|
UTSW |
5 |
115,737,147 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4152:Gcn1
|
UTSW |
5 |
115,751,413 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R4179:Gcn1
|
UTSW |
5 |
115,726,109 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4292:Gcn1
|
UTSW |
5 |
115,714,207 (GRCm39) |
missense |
possibly damaging |
0.49 |
|
R4350:Gcn1
|
UTSW |
5 |
115,741,389 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4493:Gcn1
|
UTSW |
5 |
115,732,203 (GRCm39) |
missense |
probably benign |
|
|
R4672:Gcn1
|
UTSW |
5 |
115,744,579 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4749:Gcn1
|
UTSW |
5 |
115,752,461 (GRCm39) |
missense |
probably benign |
|
|
R4753:Gcn1
|
UTSW |
5 |
115,754,537 (GRCm39) |
missense |
probably benign |
|
|
R4826:Gcn1
|
UTSW |
5 |
115,731,752 (GRCm39) |
missense |
probably benign |
|
|
R4873:Gcn1
|
UTSW |
5 |
115,714,229 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R4875:Gcn1
|
UTSW |
5 |
115,714,229 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R4932:Gcn1
|
UTSW |
5 |
115,730,203 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4992:Gcn1
|
UTSW |
5 |
115,737,225 (GRCm39) |
missense |
probably benign |
0.29 |
|
R5049:Gcn1
|
UTSW |
5 |
115,744,730 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5211:Gcn1
|
UTSW |
5 |
115,757,371 (GRCm39) |
missense |
probably benign |
0.04 |
|
R5226:Gcn1
|
UTSW |
5 |
115,726,126 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5338:Gcn1
|
UTSW |
5 |
115,721,462 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5914:Gcn1
|
UTSW |
5 |
115,748,194 (GRCm39) |
synonymous |
silent |
|
|
R5932:Gcn1
|
UTSW |
5 |
115,730,435 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R6422:Gcn1
|
UTSW |
5 |
115,747,603 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6435:Gcn1
|
UTSW |
5 |
115,749,081 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R6607:Gcn1
|
UTSW |
5 |
115,747,537 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6724:Gcn1
|
UTSW |
5 |
115,747,217 (GRCm39) |
splice site |
probably null |
|
|
R6875:Gcn1
|
UTSW |
5 |
115,726,169 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6910:Gcn1
|
UTSW |
5 |
115,744,597 (GRCm39) |
missense |
probably benign |
0.42 |
|
R6975:Gcn1
|
UTSW |
5 |
115,751,518 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7027:Gcn1
|
UTSW |
5 |
115,754,605 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7038:Gcn1
|
UTSW |
5 |
115,749,203 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7171:Gcn1
|
UTSW |
5 |
115,728,352 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7276:Gcn1
|
UTSW |
5 |
115,749,119 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7456:Gcn1
|
UTSW |
5 |
115,743,005 (GRCm39) |
nonsense |
probably null |
|
|
R7473:Gcn1
|
UTSW |
5 |
115,719,863 (GRCm39) |
missense |
probably benign |
0.09 |
|
R7517:Gcn1
|
UTSW |
5 |
115,757,755 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7714:Gcn1
|
UTSW |
5 |
115,733,359 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R7752:Gcn1
|
UTSW |
5 |
115,753,627 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7812:Gcn1
|
UTSW |
5 |
115,731,751 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R7922:Gcn1
|
UTSW |
5 |
115,752,527 (GRCm39) |
missense |
probably benign |
|
|
R8070:Gcn1
|
UTSW |
5 |
115,727,057 (GRCm39) |
missense |
probably benign |
0.09 |
|
R8218:Gcn1
|
UTSW |
5 |
115,719,588 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8329:Gcn1
|
UTSW |
5 |
115,747,921 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8413:Gcn1
|
UTSW |
5 |
115,717,698 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8795:Gcn1
|
UTSW |
5 |
115,752,454 (GRCm39) |
missense |
probably benign |
0.02 |
|
R8802:Gcn1
|
UTSW |
5 |
115,747,942 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8899:Gcn1
|
UTSW |
5 |
115,717,220 (GRCm39) |
missense |
probably benign |
0.04 |
|
R8946:Gcn1
|
UTSW |
5 |
115,733,404 (GRCm39) |
missense |
probably benign |
0.02 |
|
R8963:Gcn1
|
UTSW |
5 |
115,727,153 (GRCm39) |
missense |
probably benign |
0.25 |
|
R9006:Gcn1
|
UTSW |
5 |
115,719,566 (GRCm39) |
missense |
probably benign |
0.22 |
|
R9163:Gcn1
|
UTSW |
5 |
115,742,944 (GRCm39) |
missense |
probably benign |
|
|
R9177:Gcn1
|
UTSW |
5 |
115,719,867 (GRCm39) |
missense |
probably benign |
0.35 |
|
R9187:Gcn1
|
UTSW |
5 |
115,752,177 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9411:Gcn1
|
UTSW |
5 |
115,733,098 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R9541:Gcn1
|
UTSW |
5 |
115,754,416 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9574:Gcn1
|
UTSW |
5 |
115,713,341 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R9630:Gcn1
|
UTSW |
5 |
115,741,349 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9651:Gcn1
|
UTSW |
5 |
115,747,665 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9761:Gcn1
|
UTSW |
5 |
115,729,064 (GRCm39) |
missense |
probably benign |
0.05 |
|
R9765:Gcn1
|
UTSW |
5 |
115,735,131 (GRCm39) |
nonsense |
probably null |
|
|
Z1177:Gcn1
|
UTSW |
5 |
115,752,208 (GRCm39) |
missense |
probably damaging |
0.99 |
|
Z1191:Gcn1
|
UTSW |
5 |
115,713,352 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
| Predicted Primers |
PCR Primer
(F):5'- GCTCTGTTCAACTTCTTGGGGAC -3'
(R):5'- TAGCCAGGAAACCCAGTAGG -3'
Sequencing Primer
(F):5'- GTTCCACATCTCTGGGGTCACAG -3'
(R):5'- CAGGAAACCCAGTAGGAGGCC -3'
|
| Posted On |
2018-09-12 |
Incidental Mutation