Incidental Mutation 'R6861:Nlrc5'
| ID |
535532 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Nlrc5
|
| Ensembl Gene |
ENSMUSG00000074151 |
| Gene Name |
NLR family, CARD domain containing 5 |
| Synonyms |
AI451557 |
| MMRRC Submission |
044962-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R6861 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
8 |
| Chromosomal Location |
95160984-95253900 bp(+) (GRCm39) |
| Type of Mutation |
unclassified |
| DNA Base Change (assembly) |
G to A
at 95247857 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000138409
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000053085]
[ENSMUST00000098489]
[ENSMUST00000211816]
|
| AlphaFold |
C3VPR6 |
| Predicted Effect |
unknown
Transcript: ENSMUST00000053085
AA Change: G1645R
|
| SMART Domains |
Protein: ENSMUSP00000138322
Gene: ENSMUSG00000074151
AA Change: G1645R
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
136 |
151 |
N/A |
INTRINSIC |
|
Pfam:NACHT
|
223 |
386 |
1.8e-32 |
PFAM |
|
LRR
|
716 |
743 |
6.89e1 |
SMART |
|
LRR
|
744 |
771 |
9.86e1 |
SMART |
|
LRR
|
772 |
796 |
1.22e2 |
SMART |
|
LRR
|
844 |
870 |
2.16e2 |
SMART |
|
LRR
|
871 |
898 |
1.76e-1 |
SMART |
|
LRR
|
1006 |
1033 |
1.9e0 |
SMART |
|
LRR
|
1034 |
1061 |
4.51e1 |
SMART |
|
low complexity region
|
1141 |
1169 |
N/A |
INTRINSIC |
|
LRR
|
1240 |
1267 |
2.67e1 |
SMART |
|
LRR
|
1273 |
1295 |
1.22e1 |
SMART |
|
low complexity region
|
1341 |
1351 |
N/A |
INTRINSIC |
|
LRR
|
1519 |
1546 |
5.48e1 |
SMART |
|
LRR
|
1547 |
1574 |
3.36e1 |
SMART |
|
LRR
|
1575 |
1602 |
1.69e1 |
SMART |
|
LRR
|
1603 |
1630 |
8.99e-1 |
SMART |
|
LRR
|
1631 |
1654 |
5.26e0 |
SMART |
|
LRR
|
1659 |
1686 |
2.81e0 |
SMART |
|
LRR
|
1687 |
1714 |
1.6e-4 |
SMART |
|
LRR
|
1715 |
1742 |
1.06e0 |
SMART |
|
LRR
|
1743 |
1768 |
8e0 |
SMART |
|
LRR
|
1793 |
1820 |
2.06e1 |
SMART |
|
LRR
|
1821 |
1848 |
5.42e-2 |
SMART |
|
LRR
|
1849 |
1876 |
3.54e0 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000098489
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000211816
AA Change: G1645R
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.6%
- 20x: 98.6%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a member of the caspase recruitment domain-containing NLR family. This gene plays a role in cytokine response and antiviral immunity through its inhibition of NF-kappa-B activation and negative regulation of type I interferon signaling pathways. [provided by RefSeq, Oct 2011]
PHENOTYPE: Mice homozygous for a knock-out allele exhibit normal cytokine production induced by virus and bacteria infection. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 86 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Adamtsl4 |
G |
A |
3: 95,588,194 (GRCm39) |
R598C |
probably damaging |
Het |
| Adra2a |
T |
C |
19: 54,034,818 (GRCm39) |
L58P |
probably damaging |
Het |
| Ajm1 |
C |
CTCTA |
2: 25,469,733 (GRCm39) |
|
probably null |
Het |
| Alox5ap |
A |
G |
5: 149,201,927 (GRCm39) |
D2G |
probably damaging |
Het |
| Arid1b |
G |
A |
17: 5,377,961 (GRCm39) |
V1238M |
possibly damaging |
Het |
| Bank1 |
A |
G |
3: 135,960,764 (GRCm39) |
V31A |
probably benign |
Het |
| Bptf |
G |
A |
11: 106,953,391 (GRCm39) |
T2117M |
probably damaging |
Het |
| Cadps |
G |
A |
14: 12,522,401 (GRCm38) |
R588* |
probably null |
Het |
| Cavin4 |
A |
G |
4: 48,672,214 (GRCm39) |
I220V |
probably benign |
Het |
| Cep192 |
G |
A |
18: 67,974,699 (GRCm39) |
M1267I |
probably benign |
Het |
| Cers5 |
G |
A |
15: 99,670,244 (GRCm39) |
|
probably benign |
Het |
| Cfap65 |
A |
T |
1: 74,964,274 (GRCm39) |
I558N |
probably damaging |
Het |
| Cfh |
A |
T |
1: 140,028,621 (GRCm39) |
S1025T |
probably benign |
Het |
| Cftr |
A |
G |
6: 18,268,107 (GRCm39) |
I689V |
probably benign |
Het |
| Cgrrf1 |
T |
C |
14: 47,069,785 (GRCm39) |
I18T |
probably damaging |
Het |
| CK137956 |
A |
G |
4: 127,864,519 (GRCm39) |
S37P |
probably damaging |
Het |
| Clca4a |
T |
C |
3: 144,676,416 (GRCm39) |
D88G |
probably benign |
Het |
| Col11a1 |
G |
A |
3: 113,961,141 (GRCm39) |
G1166D |
probably damaging |
Het |
| Col24a1 |
G |
A |
3: 145,166,589 (GRCm39) |
G1075S |
probably damaging |
Het |
| Crispld2 |
C |
T |
8: 120,752,852 (GRCm39) |
T299M |
probably damaging |
Het |
| Cyb561a3 |
T |
A |
19: 10,562,701 (GRCm39) |
Y114N |
probably damaging |
Het |
| Cyp3a57 |
T |
A |
5: 145,307,773 (GRCm39) |
W147R |
possibly damaging |
Het |
| Dnah2 |
C |
A |
11: 69,346,789 (GRCm39) |
R2599L |
possibly damaging |
Het |
| Dock1 |
T |
A |
7: 134,373,207 (GRCm39) |
S525T |
probably benign |
Het |
| Drc7 |
T |
G |
8: 95,789,025 (GRCm39) |
|
probably null |
Het |
| Efhd2 |
G |
T |
4: 141,587,192 (GRCm39) |
|
probably null |
Het |
| Epb41l1 |
A |
T |
2: 156,367,142 (GRCm39) |
E658D |
probably benign |
Het |
| Evi5 |
C |
T |
5: 107,896,184 (GRCm39) |
S753N |
probably benign |
Het |
| Exoc3 |
A |
T |
13: 74,337,319 (GRCm39) |
D427E |
probably benign |
Het |
| Fbxw9 |
A |
G |
8: 85,792,740 (GRCm39) |
D363G |
probably damaging |
Het |
| Fcer2a |
T |
C |
8: 3,732,910 (GRCm39) |
Y277C |
probably damaging |
Het |
| Fstl5 |
A |
T |
3: 76,229,523 (GRCm39) |
Y108F |
probably damaging |
Het |
| Gcn1 |
A |
G |
5: 115,749,108 (GRCm39) |
D1880G |
probably benign |
Het |
| Gm4924 |
T |
A |
10: 82,214,948 (GRCm39) |
Y915* |
probably null |
Het |
| Gpr139 |
T |
A |
7: 118,743,875 (GRCm39) |
I237F |
probably benign |
Het |
| Hao2 |
A |
G |
3: 98,784,498 (GRCm39) |
L289S |
probably damaging |
Het |
| Hexim1 |
A |
G |
11: 103,007,793 (GRCm39) |
S16G |
probably benign |
Het |
| Hmgcs1 |
T |
A |
13: 120,161,535 (GRCm39) |
M109K |
probably damaging |
Het |
| Hs3st4 |
T |
A |
7: 123,996,052 (GRCm39) |
N239K |
possibly damaging |
Het |
| Hsd3b5 |
T |
A |
3: 98,529,328 (GRCm39) |
N101Y |
probably damaging |
Het |
| Idh2 |
G |
A |
7: 79,747,966 (GRCm39) |
P245S |
probably damaging |
Het |
| Irx3 |
A |
G |
8: 92,525,530 (GRCm39) |
|
probably benign |
Het |
| Lilra5 |
A |
T |
7: 4,244,931 (GRCm39) |
D234V |
probably benign |
Het |
| Lrfn5 |
G |
A |
12: 61,886,476 (GRCm39) |
S88N |
probably damaging |
Het |
| Lrp2 |
A |
T |
2: 69,343,721 (GRCm39) |
S879R |
possibly damaging |
Het |
| Lsm11 |
A |
G |
11: 45,824,781 (GRCm39) |
S249P |
probably benign |
Het |
| Ltbp1 |
C |
T |
17: 75,534,187 (GRCm39) |
A543V |
possibly damaging |
Het |
| Mbd1 |
GTCTGCATCTGCGTCTTCGTCTGCATCTGCATCTGCGTCTTCGTCTGCATCTGCATCTGC |
GTCTGCATCTGCGTCTTCGTCTGCATCTGCATCTGC |
18: 74,406,645 (GRCm39) |
|
|
Het |
| Mier2 |
C |
T |
10: 79,376,990 (GRCm39) |
|
probably benign |
Het |
| Mup6 |
G |
C |
4: 60,004,093 (GRCm39) |
G70A |
probably benign |
Het |
| Neb |
A |
G |
2: 52,085,732 (GRCm39) |
L5258P |
probably damaging |
Het |
| Nr6a1 |
A |
T |
2: 38,630,597 (GRCm39) |
F207I |
possibly damaging |
Het |
| Or2y1 |
A |
T |
11: 49,385,632 (GRCm39) |
T91S |
probably benign |
Het |
| Or5k17 |
A |
T |
16: 58,746,867 (GRCm39) |
D22E |
probably benign |
Het |
| Or8b43 |
T |
C |
9: 38,360,731 (GRCm39) |
C188R |
probably damaging |
Het |
| Osbp2 |
A |
G |
11: 3,665,191 (GRCm39) |
V51A |
possibly damaging |
Het |
| Papln |
G |
T |
12: 83,821,723 (GRCm39) |
C317F |
probably damaging |
Het |
| Pdcd7 |
T |
C |
9: 65,265,904 (GRCm39) |
S454P |
probably damaging |
Het |
| Pde4a |
C |
T |
9: 21,116,597 (GRCm39) |
T473I |
probably damaging |
Het |
| Peg10 |
CC |
CCCCATCAGGC |
6: 4,756,350 (GRCm39) |
|
probably benign |
Het |
| Peg10 |
C |
CCCATCAGGA |
6: 4,756,351 (GRCm39) |
|
probably benign |
Het |
| Peg3 |
G |
T |
7: 6,714,385 (GRCm39) |
S279* |
probably null |
Het |
| Rbl1 |
A |
G |
2: 156,994,887 (GRCm39) |
Y929H |
probably damaging |
Het |
| Rsf1 |
G |
GACGGCGGCA |
7: 97,229,116 (GRCm39) |
|
probably benign |
Het |
| Sall3 |
C |
A |
18: 81,017,590 (GRCm39) |
E113* |
probably null |
Het |
| Scn5a |
A |
C |
9: 119,359,089 (GRCm39) |
F653V |
probably damaging |
Het |
| Selenok |
T |
A |
14: 29,692,005 (GRCm39) |
N14K |
possibly damaging |
Het |
| Slc22a20 |
T |
C |
19: 6,021,838 (GRCm39) |
T426A |
probably benign |
Het |
| Slc4a2 |
T |
A |
5: 24,640,007 (GRCm39) |
S563T |
probably damaging |
Het |
| Sspo |
T |
A |
6: 48,464,889 (GRCm39) |
S3798T |
probably benign |
Het |
| Stag3 |
G |
T |
5: 138,302,969 (GRCm39) |
R63L |
possibly damaging |
Het |
| Stard9 |
A |
T |
2: 120,535,667 (GRCm39) |
M3975L |
probably benign |
Het |
| Syne2 |
C |
A |
12: 75,956,040 (GRCm39) |
T582K |
probably damaging |
Het |
| Synj1 |
G |
A |
16: 90,760,768 (GRCm39) |
Q748* |
probably null |
Het |
| Tas2r109 |
T |
C |
6: 132,957,048 (GRCm39) |
D294G |
probably benign |
Het |
| Tbl1xr1 |
C |
T |
3: 22,245,603 (GRCm39) |
T203M |
possibly damaging |
Het |
| Tbl1xr1 |
T |
A |
3: 22,245,703 (GRCm39) |
|
probably null |
Het |
| Tcf7l2 |
A |
G |
19: 55,730,955 (GRCm39) |
D19G |
probably damaging |
Het |
| Tecta |
A |
G |
9: 42,248,633 (GRCm39) |
V1923A |
possibly damaging |
Het |
| Tg |
T |
A |
15: 66,560,740 (GRCm39) |
M1034K |
probably benign |
Het |
| Ttf2 |
T |
C |
3: 100,876,941 (GRCm39) |
E8G |
possibly damaging |
Het |
| Vps13b |
T |
A |
15: 35,576,541 (GRCm39) |
V983E |
probably damaging |
Het |
| Vps35l |
A |
G |
7: 118,342,898 (GRCm39) |
H32R |
probably damaging |
Het |
| Vwa2 |
T |
C |
19: 56,890,025 (GRCm39) |
V210A |
probably benign |
Het |
| Xkr6 |
T |
A |
14: 64,057,093 (GRCm39) |
Y335N |
probably benign |
Het |
| Zfp97 |
A |
G |
17: 17,365,437 (GRCm39) |
H312R |
probably damaging |
Het |
|
| Other mutations in Nlrc5 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00158:Nlrc5
|
APN |
8 |
95,228,839 (GRCm39) |
splice site |
probably benign |
|
|
IGL00232:Nlrc5
|
APN |
8 |
95,211,251 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL00324:Nlrc5
|
APN |
8 |
95,248,107 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02715:Nlrc5
|
APN |
8 |
95,201,296 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02992:Nlrc5
|
APN |
8 |
95,233,201 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
IGL03095:Nlrc5
|
APN |
8 |
95,248,536 (GRCm39) |
splice site |
probably benign |
|
|
IGL03389:Nlrc5
|
APN |
8 |
95,248,102 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03406:Nlrc5
|
APN |
8 |
95,203,483 (GRCm39) |
missense |
probably benign |
0.01 |
|
cassis
|
UTSW |
8 |
95,203,021 (GRCm39) |
nonsense |
probably null |
|
|
cowberry
|
UTSW |
8 |
95,218,153 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
lingon
|
UTSW |
8 |
95,208,488 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0037:Nlrc5
|
UTSW |
8 |
95,216,163 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0048:Nlrc5
|
UTSW |
8 |
95,201,284 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R0092:Nlrc5
|
UTSW |
8 |
95,216,222 (GRCm39) |
splice site |
probably benign |
|
|
R0506:Nlrc5
|
UTSW |
8 |
95,219,753 (GRCm39) |
splice site |
probably benign |
|
|
R0548:Nlrc5
|
UTSW |
8 |
95,248,411 (GRCm39) |
missense |
probably null |
0.09 |
|
R2014:Nlrc5
|
UTSW |
8 |
95,252,138 (GRCm39) |
splice site |
probably benign |
|
|
R3051:Nlrc5
|
UTSW |
8 |
95,203,343 (GRCm39) |
missense |
probably benign |
0.01 |
|
R3776:Nlrc5
|
UTSW |
8 |
95,199,467 (GRCm39) |
missense |
possibly damaging |
0.48 |
|
R3837:Nlrc5
|
UTSW |
8 |
95,237,929 (GRCm39) |
splice site |
probably benign |
|
|
R4012:Nlrc5
|
UTSW |
8 |
95,202,620 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R4367:Nlrc5
|
UTSW |
8 |
95,203,192 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4400:Nlrc5
|
UTSW |
8 |
95,220,981 (GRCm39) |
missense |
probably benign |
0.08 |
|
R4469:Nlrc5
|
UTSW |
8 |
95,247,467 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4561:Nlrc5
|
UTSW |
8 |
95,203,774 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4584:Nlrc5
|
UTSW |
8 |
95,203,903 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R4758:Nlrc5
|
UTSW |
8 |
95,238,956 (GRCm39) |
missense |
possibly damaging |
0.70 |
|
R4834:Nlrc5
|
UTSW |
8 |
95,232,113 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4896:Nlrc5
|
UTSW |
8 |
95,247,844 (GRCm39) |
unclassified |
probably benign |
|
|
R5004:Nlrc5
|
UTSW |
8 |
95,247,844 (GRCm39) |
unclassified |
probably benign |
|
|
R5018:Nlrc5
|
UTSW |
8 |
95,252,080 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5115:Nlrc5
|
UTSW |
8 |
95,203,447 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
R5116:Nlrc5
|
UTSW |
8 |
95,208,488 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5126:Nlrc5
|
UTSW |
8 |
95,201,299 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R5148:Nlrc5
|
UTSW |
8 |
95,203,321 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5224:Nlrc5
|
UTSW |
8 |
95,220,944 (GRCm39) |
missense |
probably benign |
0.26 |
|
R5527:Nlrc5
|
UTSW |
8 |
95,217,044 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5640:Nlrc5
|
UTSW |
8 |
95,202,421 (GRCm39) |
missense |
probably benign |
0.02 |
|
R5705:Nlrc5
|
UTSW |
8 |
95,202,385 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5778:Nlrc5
|
UTSW |
8 |
95,206,154 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R5830:Nlrc5
|
UTSW |
8 |
95,199,542 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5850:Nlrc5
|
UTSW |
8 |
95,247,675 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5978:Nlrc5
|
UTSW |
8 |
95,215,221 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6335:Nlrc5
|
UTSW |
8 |
95,228,902 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6372:Nlrc5
|
UTSW |
8 |
95,206,378 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6486:Nlrc5
|
UTSW |
8 |
95,247,927 (GRCm39) |
splice site |
probably null |
|
|
R6765:Nlrc5
|
UTSW |
8 |
95,216,996 (GRCm39) |
missense |
probably benign |
0.20 |
|
R6869:Nlrc5
|
UTSW |
8 |
95,248,583 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7134:Nlrc5
|
UTSW |
8 |
95,206,350 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7204:Nlrc5
|
UTSW |
8 |
95,218,153 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R7231:Nlrc5
|
UTSW |
8 |
95,248,433 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7309:Nlrc5
|
UTSW |
8 |
95,200,670 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7368:Nlrc5
|
UTSW |
8 |
95,203,021 (GRCm39) |
nonsense |
probably null |
|
|
R7497:Nlrc5
|
UTSW |
8 |
95,248,598 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7606:Nlrc5
|
UTSW |
8 |
95,203,745 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
R7611:Nlrc5
|
UTSW |
8 |
95,239,276 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7685:Nlrc5
|
UTSW |
8 |
95,248,028 (GRCm39) |
splice site |
probably null |
|
|
R7810:Nlrc5
|
UTSW |
8 |
95,231,772 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R7829:Nlrc5
|
UTSW |
8 |
95,248,397 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7910:Nlrc5
|
UTSW |
8 |
95,219,720 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7921:Nlrc5
|
UTSW |
8 |
95,214,292 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8131:Nlrc5
|
UTSW |
8 |
95,208,420 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8237:Nlrc5
|
UTSW |
8 |
95,252,753 (GRCm39) |
missense |
unknown |
|
|
R8493:Nlrc5
|
UTSW |
8 |
95,249,848 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8888:Nlrc5
|
UTSW |
8 |
95,252,118 (GRCm39) |
missense |
probably benign |
0.04 |
|
R8964:Nlrc5
|
UTSW |
8 |
95,232,116 (GRCm39) |
missense |
possibly damaging |
0.54 |
|
R9053:Nlrc5
|
UTSW |
8 |
95,217,013 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9058:Nlrc5
|
UTSW |
8 |
95,238,938 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R9161:Nlrc5
|
UTSW |
8 |
95,213,274 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R9278:Nlrc5
|
UTSW |
8 |
95,237,908 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9285:Nlrc5
|
UTSW |
8 |
95,199,604 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9405:Nlrc5
|
UTSW |
8 |
95,199,652 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9591:Nlrc5
|
UTSW |
8 |
95,249,309 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9620:Nlrc5
|
UTSW |
8 |
95,203,034 (GRCm39) |
missense |
probably benign |
0.44 |
|
RF021:Nlrc5
|
UTSW |
8 |
95,203,516 (GRCm39) |
missense |
probably benign |
0.16 |
|
Z1088:Nlrc5
|
UTSW |
8 |
95,231,092 (GRCm39) |
missense |
possibly damaging |
0.48 |
|
Z1177:Nlrc5
|
UTSW |
8 |
95,233,208 (GRCm39) |
critical splice donor site |
probably null |
|
|
| Predicted Primers |
PCR Primer
(F):5'- AGCTTGAGTCACAACCAGATC -3'
(R):5'- ATCTCCGATCTGGTTGCGAC -3'
Sequencing Primer
(F):5'- GTACCCAGTGCTTAGCTGC -3'
(R):5'- TCCGATCTGGTTGCGACTCAAG -3'
|
| Posted On |
2018-09-12 |
Incidental Mutation