Incidental Mutation 'IGL01010:Psg26'
ID53649
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Psg26
Ensembl Gene ENSMUSG00000070799
Gene Namepregnancy-specific glycoprotein 26
SynonymsEG574429, cea14
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.051) question?
Stock #IGL01010
Quality Score
Status
Chromosome7
Chromosomal Location18474582-18484177 bp(-) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) T to C at 18478330 bp
ZygosityHeterozygous
Amino Acid Change Serine to Glycine at position 367 (S367G)
Ref Sequence ENSEMBL: ENSMUSP00000092392 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000094798]
Predicted Effect possibly damaging
Transcript: ENSMUST00000094798
AA Change: S367G

PolyPhen 2 Score 0.829 (Sensitivity: 0.84; Specificity: 0.93)
SMART Domains Protein: ENSMUSP00000092392
Gene: ENSMUSG00000070799
AA Change: S367G

DomainStartEndE-ValueType
IG 40 141 4.93e-3 SMART
IG 160 261 2.39e-1 SMART
IG 280 379 6.07e-3 SMART
IGc2 397 461 5.48e-10 SMART
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 26 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
1700030K09Rik C A 8: 72,445,215 S155R probably damaging Het
Acss3 G T 10: 107,023,849 probably benign Het
Ano4 G A 10: 88,960,600 T680I probably benign Het
Drosha C T 15: 12,827,289 probably benign Het
Ehd3 A G 17: 73,827,489 D281G probably damaging Het
Exoc5 A G 14: 49,037,755 L196P probably damaging Het
Gal3st1 T C 11: 3,996,914 probably benign Het
Gart G A 16: 91,643,092 R4* probably null Het
Gm21738 T A 14: 19,417,361 T56S probably benign Het
Gm3573 T A 14: 42,187,566 I141L probably benign Het
Gpr6 A G 10: 41,071,151 M145T probably benign Het
Kcns3 T C 12: 11,092,426 M91V probably benign Het
Marc2 T G 1: 184,819,316 I308L probably benign Het
Mto1 A G 9: 78,461,643 K529R probably benign Het
Naip2 A T 13: 100,154,938 V1164D probably damaging Het
Olfr1053 A T 2: 86,314,944 I114N probably damaging Het
Olfr695 T C 7: 106,874,253 probably benign Het
Plekha1 T C 7: 130,902,254 probably benign Het
Rps6kb1 T C 11: 86,502,766 M513V probably benign Het
Slitrk3 C T 3: 73,049,273 G722D probably benign Het
Sssca1 A G 19: 5,731,265 S78P probably damaging Het
Stag1 A G 9: 100,945,933 E1005G probably benign Het
Tgfbr2 A T 9: 116,129,980 L122Q possibly damaging Het
Traf2 G A 2: 25,520,438 R400* probably null Het
Trim33 C T 3: 103,346,715 Q153* probably null Het
Zmynd15 T C 11: 70,465,916 Y551H probably damaging Het
Other mutations in Psg26
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01383:Psg26 APN 7 18480254 missense possibly damaging 0.90
IGL01453:Psg26 APN 7 18480074 missense possibly damaging 0.91
IGL01603:Psg26 APN 7 18475103 missense probably damaging 0.98
IGL02201:Psg26 APN 7 18480146 missense probably benign 0.04
IGL02468:Psg26 APN 7 18478462 missense probably damaging 0.96
IGL02648:Psg26 APN 7 18482766 missense probably benign 0.05
IGL02812:Psg26 APN 7 18475155 missense probably benign 0.00
R0226:Psg26 UTSW 7 18483958 missense possibly damaging 0.81
R0352:Psg26 UTSW 7 18475256 missense probably benign 0.00
R0369:Psg26 UTSW 7 18482556 nonsense probably null
R0718:Psg26 UTSW 7 18475235 missense probably benign 0.23
R0718:Psg26 UTSW 7 18478287 missense probably benign 0.18
R1710:Psg26 UTSW 7 18480041 missense probably damaging 0.99
R1899:Psg26 UTSW 7 18478425 missense probably benign 0.01
R1958:Psg26 UTSW 7 18478339 missense probably benign 0.04
R2102:Psg26 UTSW 7 18475142 missense probably damaging 1.00
R3766:Psg26 UTSW 7 18475071 missense probably benign
R4544:Psg26 UTSW 7 18478539 missense probably damaging 1.00
R4977:Psg26 UTSW 7 18475310 missense probably benign 0.11
R5000:Psg26 UTSW 7 18480132 missense possibly damaging 0.95
R5376:Psg26 UTSW 7 18480105 missense probably benign
R5416:Psg26 UTSW 7 18482600 missense probably benign
R5435:Psg26 UTSW 7 18478473 missense possibly damaging 0.60
R6000:Psg26 UTSW 7 18482692 nonsense probably null
R6285:Psg26 UTSW 7 18482828 missense probably benign
R7062:Psg26 UTSW 7 18482596 missense probably damaging 1.00
R7083:Psg26 UTSW 7 18480009 nonsense probably null
R7513:Psg26 UTSW 7 18475300 missense probably benign 0.03
R7817:Psg26 UTSW 7 18482647 missense not run
R7857:Psg26 UTSW 7 18478290 missense possibly damaging 0.71
R7905:Psg26 UTSW 7 18475317 missense probably benign 0.00
R8047:Psg26 UTSW 7 18478549 missense possibly damaging 0.50
R8789:Psg26 UTSW 7 18482569 missense probably damaging 1.00
R8877:Psg26 UTSW 7 18483940 missense probably benign 0.01
Z1177:Psg26 UTSW 7 18480291 missense probably benign 0.02
Posted On2013-06-28