Mutagenetix > Incidental Mutation

Incidental Mutation 'R6889:Igsf10'

537087

Institutional Source

Beutler Lab

Gene Symbol

Igsf10

Ensembl Gene

ENSMUSG00000036334

Gene Name

immunoglobulin superfamily, member 10

Synonyms

Adlican2, CMF608, 6530405F15Rik

MMRRC Submission

044983-MU

Accession Numbers

Genbank: NM_001162884; MGI: 1923481

Essential gene?

Possibly non essential (E-score: 0.279) question?

Stock #

R6889 (G1)

Quality Score

225.009

Status

Not validated

Chromosome

Chromosomal Location

59316735-59344394 bp(-) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

A to C at 59331933 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Serine to Alanine at position 276 (S276A)

Ref Sequence

ENSEMBL: ENSMUSP00000141391 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000039419] [ENSMUST00000193455] [ENSMUST00000194546]

AlphaFold

Q3V1M1

Predicted Effect

probably benign
Transcript: ENSMUST00000039419
AA Change: S276A

PolyPhen 2 Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)

SMART Domains

Protein: ENSMUSP00000037246
Gene: ENSMUSG00000036334
AA Change: S276A

Domain	Start	End	E-Value	Type
signal peptide	1	25	N/A	INTRINSIC
LRRNT	28	61	3.24e-4	SMART
LRR	57	79	9.24e1	SMART
LRR	80	103	2.02e-1	SMART
LRR	104	127	7.16e0	SMART
LRR_TYP	128	151	1.2e-3	SMART
LRR	152	175	1.25e-1	SMART
LRR	188	207	2.33e2	SMART
LRRCT	219	280	4.19e-4	SMART
IGc2	488	558	2.34e-4	SMART
IGc2	586	652	7.88e-11	SMART
low complexity region	917	930	N/A	INTRINSIC
low complexity region	1175	1185	N/A	INTRINSIC
low complexity region	1245	1263	N/A	INTRINSIC
low complexity region	1311	1321	N/A	INTRINSIC
low complexity region	1449	1465	N/A	INTRINSIC
IGc2	1632	1701	7.69e-14	SMART
IGc2	1729	1798	5.07e-14	SMART
IGc2	1826	1895	2.19e-9	SMART
IGc2	1925	1994	4.59e-12	SMART
IGc2	2022	2097	1.33e-8	SMART
IGc2	2125	2191	2.96e-15	SMART
IGc2	2223	2291	2.03e-4	SMART
IGc2	2321	2389	9.99e-13	SMART
IGc2	2416	2484	3.03e-12	SMART
IGc2	2512	2583	7.76e-10	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000193455
AA Change: S276A

PolyPhen 2 Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)

SMART Domains

Protein: ENSMUSP00000141971
Gene: ENSMUSG00000036334
AA Change: S276A

Domain	Start	End	E-Value	Type
signal peptide	1	25	N/A	INTRINSIC
LRRNT	28	61	3.24e-4	SMART
LRR	57	79	9.24e1	SMART
LRR	80	103	2.02e-1	SMART
LRR	104	127	7.16e0	SMART
LRR_TYP	128	151	1.2e-3	SMART
LRR	152	175	1.25e-1	SMART
LRR	188	207	2.33e2	SMART
LRRCT	219	280	4.19e-4	SMART
IGc2	488	558	2.34e-4	SMART
IGc2	586	652	7.88e-11	SMART
low complexity region	917	930	N/A	INTRINSIC
low complexity region	1175	1185	N/A	INTRINSIC
low complexity region	1245	1263	N/A	INTRINSIC
low complexity region	1311	1321	N/A	INTRINSIC
low complexity region	1449	1465	N/A	INTRINSIC
IGc2	1632	1701	7.69e-14	SMART
IGc2	1729	1798	5.07e-14	SMART
IGc2	1826	1895	2.19e-9	SMART
IGc2	1925	1994	4.59e-12	SMART
IGc2	2022	2097	1.33e-8	SMART
IGc2	2125	2191	2.96e-15	SMART
IGc2	2223	2291	2.03e-4	SMART
IGc2	2321	2389	9.99e-13	SMART
IGc2	2416	2484	3.03e-12	SMART
IGc2	2512	2583	7.76e-10	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000194546
AA Change: S276A

PolyPhen 2 Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)

SMART Domains

Protein: ENSMUSP00000141391
Gene: ENSMUSG00000036334
AA Change: S276A

Domain	Start	End	E-Value	Type
signal peptide	1	25	N/A	INTRINSIC
LRRNT	28	61	3.24e-4	SMART
LRR	57	79	9.24e1	SMART
LRR	80	103	2.02e-1	SMART
LRR	104	127	7.16e0	SMART
LRR_TYP	128	151	1.2e-3	SMART
LRR	152	175	1.25e-1	SMART
LRR	188	207	2.33e2	SMART
LRRCT	219	280	4.19e-4	SMART
IGc2	488	558	2.34e-4	SMART
IGc2	586	652	7.88e-11	SMART
low complexity region	917	930	N/A	INTRINSIC
low complexity region	1175	1185	N/A	INTRINSIC
low complexity region	1245	1263	N/A	INTRINSIC
low complexity region	1311	1321	N/A	INTRINSIC
low complexity region	1449	1465	N/A	INTRINSIC
IGc2	1632	1701	7.69e-14	SMART
IGc2	1729	1798	5.07e-14	SMART
IGc2	1826	1895	2.19e-9	SMART
IGc2	1925	1994	4.59e-12	SMART
IGc2	2022	2097	1.33e-8	SMART
IGc2	2125	2191	2.96e-15	SMART
IGc2	2223	2291	2.03e-4	SMART
IGc2	2321	2389	9.99e-13	SMART
IGc2	2416	2484	3.03e-12	SMART
IGc2	2512	2583	7.76e-10	SMART

Coding Region Coverage

1x: 100.0%
3x: 99.9%
10x: 99.4%
20x: 98.1%

Validation Efficiency

Allele List at MGI

All alleles(2) : Targeted, other(2)

Other mutations in this stock

Total: 60 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
2310002L09Rik	A	T	4: 73,943,053 (GRCm38)	D103E	probably benign	Het
Abcc3	A	T	11: 94,375,555 (GRCm38)	S70T	possibly damaging	Het
Atp6v0a1	A	G	11: 101,029,183 (GRCm38)	Y214C	possibly damaging	Het
Azi2	A	G	9: 118,049,895 (GRCm38)		probably null	Het
BC067074	C	A	13: 113,318,378 (GRCm38)	S319R	probably damaging	Het
Cacnb2	T	A	2: 14,986,015 (GRCm38)	V636E	possibly damaging	Het
Cd8a	A	C	6: 71,374,562 (GRCm38)	T169P	probably damaging	Het
Cfap44	G	A	16: 44,404,132 (GRCm38)	V68I	probably benign	Het
Eea1	G	T	10: 96,037,478 (GRCm38)	C1134F	probably benign	Het
Ehmt2	T	G	17: 34,912,772 (GRCm38)	F1192V	probably damaging	Het
Emc1	T	C	4: 139,365,350 (GRCm38)	F531L	probably damaging	Het
Eme1	G	A	11: 94,650,477 (GRCm38)	T173I	probably benign	Het
Gli2	A	T	1: 118,844,416 (GRCm38)	C520S	probably damaging	Het
Gm43302	T	C	5: 105,280,138 (GRCm38)	K186E	probably benign	Het
Gpr108	A	T	17: 57,236,990 (GRCm38)	N405K	probably damaging	Het
Hmgcl	C	A	4: 135,955,642 (GRCm38)	T135N	probably benign	Het
Hydin	G	A	8: 110,532,856 (GRCm38)	D2487N	possibly damaging	Het
Igfl3	G	T	7: 18,179,800 (GRCm38)	R25L	probably benign	Het
Kctd1	A	G	18: 14,973,988 (GRCm38)	S211P	probably damaging	Het
Kctd7	A	T	5: 130,152,501 (GRCm38)	Q255L	probably benign	Het
Lrig1	A	G	6: 94,625,063 (GRCm38)	Y270H	probably benign	Het
Muc5ac	C	T	7: 141,809,744 (GRCm38)		probably benign	Het
Myh15	A	G	16: 49,153,111 (GRCm38)	N1248S	possibly damaging	Het
Nod1	A	G	6: 54,944,109 (GRCm38)	F408S	probably benign	Het
Nrp1	T	C	8: 128,493,057 (GRCm38)	F652S	probably damaging	Het
Olfr1338	G	A	4: 118,754,307 (GRCm38)	T79I	probably damaging	Het
Olfr487	A	T	7: 108,211,918 (GRCm38)	F204I	probably benign	Het
Olfr574	A	T	7: 102,948,768 (GRCm38)	H91L	possibly damaging	Het
Olfr821	T	C	10: 130,034,532 (GRCm38)	M302T	probably benign	Het
Opa1	G	T	16: 29,620,868 (GRCm38)	R792L	probably benign	Het
Pcdha6	G	T	18: 36,968,343 (GRCm38)	L196F	probably damaging	Het
Pdia2	A	T	17: 26,196,970 (GRCm38)	Y347*	probably null	Het
Pdpr	G	T	8: 111,124,613 (GRCm38)		probably null	Het
Pigt	T	A	2: 164,507,331 (GRCm38)	L518Q	probably damaging	Het
Ppfibp2	A	C	7: 107,737,981 (GRCm38)	D591A	possibly damaging	Het
Prrg2	G	A	7: 45,059,989 (GRCm38)	T97M	possibly damaging	Het
Qars	A	G	9: 108,513,183 (GRCm38)	T428A	probably damaging	Het
Rai1	T	C	11: 60,185,715 (GRCm38)	F202L	probably damaging	Het
Rars	A	T	11: 35,808,486 (GRCm38)	M660K	probably damaging	Het
Rsf1	GCGGCGGCG	GCGGCGGCGTCGGCGGCG	7: 97,579,925 (GRCm38)		probably benign	Het
Slc16a6	A	C	11: 109,455,040 (GRCm38)	F382V	probably damaging	Het
Slc30a7	T	C	3: 115,954,153 (GRCm38)	T330A	probably damaging	Het
Smc1b	A	T	15: 85,067,759 (GRCm38)	L1157Q	probably damaging	Het
Snx4	G	T	16: 33,251,470 (GRCm38)	A4S	possibly damaging	Het
Sv2b	A	C	7: 75,125,767 (GRCm38)		probably null	Het
Syt9	A	T	7: 107,425,286 (GRCm38)	I129L	probably damaging	Het
Ttbk2	T	C	2: 120,773,353 (GRCm38)	E198G	probably damaging	Het
Ubr3	A	T	2: 69,944,300 (GRCm38)	D488V	possibly damaging	Het
Ush2a	T	A	1: 188,797,871 (GRCm38)	C3286S	probably damaging	Het
Vill	A	G	9: 119,065,882 (GRCm38)	D56G	possibly damaging	Het
Vmn1r41	A	T	6: 89,747,370 (GRCm38)	I298F	probably damaging	Het
Vmn2r2	A	T	3: 64,117,267 (GRCm38)	V631D	probably damaging	Het
Vmn2r32	A	G	7: 7,472,574 (GRCm38)	S437P	possibly damaging	Het
Vmn2r53	A	G	7: 12,601,142 (GRCm38)	V197A	probably benign	Het
Wasf1	A	T	10: 40,920,369 (GRCm38)	I32F	probably damaging	Het
Wasf2	G	T	4: 133,194,730 (GRCm38)	A387S	unknown	Het
Wdr92	G	A	11: 17,222,309 (GRCm38)	V133M	probably damaging	Het
Zbtb14	G	A	17: 69,387,679 (GRCm38)	C124Y	probably damaging	Het
Zfp462	G	T	4: 55,007,671 (GRCm38)	A37S	probably damaging	Het
Zfp532	A	G	18: 65,686,990 (GRCm38)	E882G	possibly damaging	Het

Other mutations in Igsf10

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00773:Igsf10	APN	3	59,331,539 (GRCm38)	missense	probably benign	0.03
IGL00790:Igsf10	APN	3	59,319,517 (GRCm38)	missense	probably damaging	1.00
IGL00916:Igsf10	APN	3	59,331,127 (GRCm38)	missense	probably damaging	0.97
IGL00928:Igsf10	APN	3	59,330,597 (GRCm38)	missense	probably benign	0.00
IGL01066:Igsf10	APN	3	59,327,782 (GRCm38)	critical splice donor site	probably null
IGL01107:Igsf10	APN	3	59,331,524 (GRCm38)	missense	probably damaging	1.00
IGL01420:Igsf10	APN	3	59,319,650 (GRCm38)	missense	probably benign	0.02
IGL01533:Igsf10	APN	3	59,319,230 (GRCm38)	missense	probably damaging	0.98
IGL01537:Igsf10	APN	3	59,330,031 (GRCm38)	missense	probably benign	0.00
IGL01676:Igsf10	APN	3	59,329,335 (GRCm38)	missense	probably benign	0.17
IGL01676:Igsf10	APN	3	59,326,011 (GRCm38)	missense	probably benign	0.06
IGL01960:Igsf10	APN	3	59,318,737 (GRCm38)	missense	probably benign	0.00
IGL02123:Igsf10	APN	3	59,318,660 (GRCm38)	missense	probably damaging	0.97
IGL02198:Igsf10	APN	3	59,325,978 (GRCm38)	missense	possibly damaging	0.95
IGL02268:Igsf10	APN	3	59,331,152 (GRCm38)	nonsense	probably null
IGL02313:Igsf10	APN	3	59,330,690 (GRCm38)	missense	probably benign	0.01
IGL02368:Igsf10	APN	3	59,328,231 (GRCm38)	missense	probably benign
IGL02494:Igsf10	APN	3	59,328,006 (GRCm38)	missense	probably damaging	0.98
IGL02549:Igsf10	APN	3	59,329,241 (GRCm38)	missense	probably benign	0.03
IGL02616:Igsf10	APN	3	59,318,606 (GRCm38)	missense	probably benign	0.06
IGL02957:Igsf10	APN	3	59,330,864 (GRCm38)	missense	probably damaging	1.00
IGL03067:Igsf10	APN	3	59,318,918 (GRCm38)	missense	probably benign	0.25
IGL03104:Igsf10	APN	3	59,319,484 (GRCm38)	missense	probably damaging	1.00
IGL03124:Igsf10	APN	3	59,319,665 (GRCm38)	missense	probably benign	0.01
IGL03212:Igsf10	APN	3	59,328,165 (GRCm38)	missense	probably benign	0.09
IGL03347:Igsf10	APN	3	59,331,900 (GRCm38)	missense	possibly damaging	0.94
IGL03357:Igsf10	APN	3	59,336,211 (GRCm38)	missense	probably benign	0.35
F6893:Igsf10	UTSW	3	59,331,060 (GRCm38)	missense	probably damaging	1.00
FR4449:Igsf10	UTSW	3	59,319,110 (GRCm38)	missense	probably damaging	1.00
PIT1430001:Igsf10	UTSW	3	59,328,158 (GRCm38)	missense	probably benign	0.06
PIT4402001:Igsf10	UTSW	3	59,325,579 (GRCm38)	missense	probably benign	0.00
PIT4810001:Igsf10	UTSW	3	59,318,482 (GRCm38)	missense	probably damaging	1.00
R0068:Igsf10	UTSW	3	59,330,624 (GRCm38)	missense	probably damaging	0.98
R0095:Igsf10	UTSW	3	59,331,196 (GRCm38)	nonsense	probably null
R0095:Igsf10	UTSW	3	59,331,196 (GRCm38)	nonsense	probably null
R0112:Igsf10	UTSW	3	59,326,008 (GRCm38)	missense	probably benign	0.00
R0141:Igsf10	UTSW	3	59,330,832 (GRCm38)	missense	probably damaging	1.00
R0538:Igsf10	UTSW	3	59,320,106 (GRCm38)	missense	probably damaging	0.99
R0551:Igsf10	UTSW	3	59,328,668 (GRCm38)	missense	probably benign	0.01
R0556:Igsf10	UTSW	3	59,328,875 (GRCm38)	missense	probably benign	0.02
R0582:Igsf10	UTSW	3	59,319,767 (GRCm38)	missense	probably benign	0.00
R0630:Igsf10	UTSW	3	59,326,062 (GRCm38)	missense	probably damaging	1.00
R0675:Igsf10	UTSW	3	59,328,594 (GRCm38)	missense	probably benign	0.14
R0948:Igsf10	UTSW	3	59,331,104 (GRCm38)	missense	probably damaging	1.00
R1252:Igsf10	UTSW	3	59,331,848 (GRCm38)	missense	probably benign	0.03
R1412:Igsf10	UTSW	3	59,327,775 (GRCm38)	splice site	probably benign
R1473:Igsf10	UTSW	3	59,318,767 (GRCm38)	missense	probably damaging	1.00
R1585:Igsf10	UTSW	3	59,330,417 (GRCm38)	missense	probably damaging	1.00
R1650:Igsf10	UTSW	3	59,326,162 (GRCm38)	missense	probably damaging	1.00
R1660:Igsf10	UTSW	3	59,331,285 (GRCm38)	missense	probably damaging	1.00
R1671:Igsf10	UTSW	3	59,328,500 (GRCm38)	nonsense	probably null
R1748:Igsf10	UTSW	3	59,319,093 (GRCm38)	missense	probably damaging	1.00
R1758:Igsf10	UTSW	3	59,329,196 (GRCm38)	missense	probably benign	0.09
R1856:Igsf10	UTSW	3	59,331,272 (GRCm38)	missense	possibly damaging	0.63
R1912:Igsf10	UTSW	3	59,329,572 (GRCm38)	missense	probably benign	0.40
R2148:Igsf10	UTSW	3	59,336,577 (GRCm38)	missense	possibly damaging	0.77
R2155:Igsf10	UTSW	3	59,331,680 (GRCm38)	missense	probably damaging	1.00
R2509:Igsf10	UTSW	3	59,331,866 (GRCm38)	missense	probably damaging	1.00
R2511:Igsf10	UTSW	3	59,331,866 (GRCm38)	missense	probably damaging	1.00
R2680:Igsf10	UTSW	3	59,325,454 (GRCm38)	missense	probably benign	0.14
R2913:Igsf10	UTSW	3	59,331,736 (GRCm38)	missense	possibly damaging	0.70
R2927:Igsf10	UTSW	3	59,329,427 (GRCm38)	missense	probably benign
R3547:Igsf10	UTSW	3	59,336,514 (GRCm38)	missense	probably damaging	1.00
R3547:Igsf10	UTSW	3	59,330,541 (GRCm38)	missense	probably benign	0.02
R3548:Igsf10	UTSW	3	59,336,514 (GRCm38)	missense	probably damaging	1.00
R3620:Igsf10	UTSW	3	59,336,331 (GRCm38)	missense	probably damaging	1.00
R3732:Igsf10	UTSW	3	59,325,714 (GRCm38)	missense	probably benign	0.29
R3743:Igsf10	UTSW	3	59,326,125 (GRCm38)	missense	possibly damaging	0.69
R3973:Igsf10	UTSW	3	59,331,924 (GRCm38)	missense	probably damaging	1.00
R4005:Igsf10	UTSW	3	59,328,560 (GRCm38)	missense	probably benign	0.00
R4184:Igsf10	UTSW	3	59,319,731 (GRCm38)	missense	probably damaging	1.00
R4302:Igsf10	UTSW	3	59,318,750 (GRCm38)	missense	probably damaging	1.00
R4404:Igsf10	UTSW	3	59,329,551 (GRCm38)	missense	probably benign	0.04
R4575:Igsf10	UTSW	3	59,330,100 (GRCm38)	missense	probably benign
R4676:Igsf10	UTSW	3	59,325,949 (GRCm38)	missense	probably benign	0.23
R4700:Igsf10	UTSW	3	59,320,330 (GRCm38)	missense	probably damaging	0.99
R4765:Igsf10	UTSW	3	59,329,705 (GRCm38)	missense	probably benign	0.01
R4986:Igsf10	UTSW	3	59,328,606 (GRCm38)	missense	probably benign	0.24
R5012:Igsf10	UTSW	3	59,318,722 (GRCm38)	missense	probably damaging	1.00
R5070:Igsf10	UTSW	3	59,328,293 (GRCm38)	missense	probably benign	0.02
R5083:Igsf10	UTSW	3	59,326,273 (GRCm38)	missense	probably damaging	1.00
R5336:Igsf10	UTSW	3	59,320,132 (GRCm38)	missense	probably damaging	1.00
R5462:Igsf10	UTSW	3	59,325,754 (GRCm38)	missense	probably damaging	1.00
R5648:Igsf10	UTSW	3	59,328,153 (GRCm38)	missense	probably benign	0.01
R5810:Igsf10	UTSW	3	59,319,071 (GRCm38)	missense	probably damaging	1.00
R5871:Igsf10	UTSW	3	59,330,411 (GRCm38)	missense	possibly damaging	0.83
R5880:Igsf10	UTSW	3	59,330,831 (GRCm38)	missense	probably damaging	1.00
R5935:Igsf10	UTSW	3	59,328,157 (GRCm38)	missense	probably benign	0.12
R5979:Igsf10	UTSW	3	59,336,473 (GRCm38)	missense	probably damaging	1.00
R6145:Igsf10	UTSW	3	59,331,656 (GRCm38)	missense	possibly damaging	0.83
R6222:Igsf10	UTSW	3	59,318,915 (GRCm38)	missense	possibly damaging	0.90
R6224:Igsf10	UTSW	3	59,325,510 (GRCm38)	missense	probably damaging	1.00
R6264:Igsf10	UTSW	3	59,328,507 (GRCm38)	missense	possibly damaging	0.88
R6283:Igsf10	UTSW	3	59,319,449 (GRCm38)	missense	probably damaging	1.00
R6336:Igsf10	UTSW	3	59,330,339 (GRCm38)	missense	probably benign	0.00
R6490:Igsf10	UTSW	3	59,329,571 (GRCm38)	missense	probably benign	0.06
R6785:Igsf10	UTSW	3	59,319,244 (GRCm38)	missense	probably damaging	1.00
R6873:Igsf10	UTSW	3	59,328,444 (GRCm38)	missense	probably benign
R7024:Igsf10	UTSW	3	59,331,701 (GRCm38)	missense	probably benign	0.00
R7056:Igsf10	UTSW	3	59,331,080 (GRCm38)	missense	probably damaging	1.00
R7128:Igsf10	UTSW	3	59,328,905 (GRCm38)	missense	probably benign
R7251:Igsf10	UTSW	3	59,319,454 (GRCm38)	missense	probably damaging	1.00
R7313:Igsf10	UTSW	3	59,329,416 (GRCm38)	missense	probably benign	0.05
R7340:Igsf10	UTSW	3	59,325,768 (GRCm38)	missense	probably damaging	1.00
R7447:Igsf10	UTSW	3	59,331,801 (GRCm38)	missense	probably benign	0.39
R7506:Igsf10	UTSW	3	59,319,354 (GRCm38)	missense	probably damaging	1.00
R7678:Igsf10	UTSW	3	59,319,340 (GRCm38)	missense	possibly damaging	0.81
R7695:Igsf10	UTSW	3	59,326,191 (GRCm38)	missense	probably damaging	1.00
R7709:Igsf10	UTSW	3	59,331,543 (GRCm38)	missense	probably damaging	0.96
R7749:Igsf10	UTSW	3	59,329,128 (GRCm38)	missense	possibly damaging	0.88
R7808:Igsf10	UTSW	3	59,328,068 (GRCm38)	missense	probably benign	0.00
R7850:Igsf10	UTSW	3	59,319,632 (GRCm38)	missense	probably benign	0.33
R7879:Igsf10	UTSW	3	59,330,724 (GRCm38)	missense	probably damaging	1.00
R7886:Igsf10	UTSW	3	59,328,327 (GRCm38)	missense	probably benign	0.01
R7891:Igsf10	UTSW	3	59,328,411 (GRCm38)	nonsense	probably null
R7946:Igsf10	UTSW	3	59,319,704 (GRCm38)	missense	possibly damaging	0.69
R7948:Igsf10	UTSW	3	59,331,858 (GRCm38)	missense	probably benign	0.02
R8004:Igsf10	UTSW	3	59,329,709 (GRCm38)	missense	probably benign	0.01
R8096:Igsf10	UTSW	3	59,328,959 (GRCm38)	missense	probably damaging	0.98
R8141:Igsf10	UTSW	3	59,330,528 (GRCm38)	missense	probably damaging	0.96
R8183:Igsf10	UTSW	3	59,330,615 (GRCm38)	missense	probably benign	0.04
R8203:Igsf10	UTSW	3	59,328,833 (GRCm38)	missense	probably benign	0.11
R8325:Igsf10	UTSW	3	59,318,533 (GRCm38)	missense	probably damaging	0.96
R8350:Igsf10	UTSW	3	59,331,528 (GRCm38)	missense	probably damaging	1.00
R8387:Igsf10	UTSW	3	59,329,143 (GRCm38)	missense	probably damaging	1.00
R8488:Igsf10	UTSW	3	59,320,010 (GRCm38)	missense	probably damaging	1.00
R8697:Igsf10	UTSW	3	59,318,887 (GRCm38)	missense	probably benign	0.02
R8786:Igsf10	UTSW	3	59,330,642 (GRCm38)	missense	probably benign	0.25
R8804:Igsf10	UTSW	3	59,336,455 (GRCm38)	missense	probably damaging	1.00
R8886:Igsf10	UTSW	3	59,329,989 (GRCm38)	missense	probably benign	0.00
R8902:Igsf10	UTSW	3	59,336,212 (GRCm38)	missense	probably benign	0.00
R8906:Igsf10	UTSW	3	59,326,318 (GRCm38)	missense	probably benign	0.01
R8917:Igsf10	UTSW	3	59,319,467 (GRCm38)	missense	possibly damaging	0.69
R9051:Igsf10	UTSW	3	59,329,247 (GRCm38)	missense	probably benign	0.00
R9178:Igsf10	UTSW	3	59,326,059 (GRCm38)	missense	possibly damaging	0.69
R9228:Igsf10	UTSW	3	59,336,422 (GRCm38)	missense	probably damaging	1.00
R9230:Igsf10	UTSW	3	59,336,422 (GRCm38)	missense	probably damaging	1.00
R9231:Igsf10	UTSW	3	59,336,422 (GRCm38)	missense	probably damaging	1.00
R9232:Igsf10	UTSW	3	59,336,422 (GRCm38)	missense	probably damaging	1.00
R9417:Igsf10	UTSW	3	59,329,105 (GRCm38)	missense	possibly damaging	0.94
R9609:Igsf10	UTSW	3	59,319,448 (GRCm38)	missense	probably damaging	1.00
R9631:Igsf10	UTSW	3	59,330,483 (GRCm38)	missense	probably damaging	1.00
R9689:Igsf10	UTSW	3	59,326,203 (GRCm38)	missense	probably damaging	1.00
R9762:Igsf10	UTSW	3	59,329,685 (GRCm38)	missense	probably damaging	1.00
R9770:Igsf10	UTSW	3	59,319,778 (GRCm38)	missense	probably benign	0.07
R9798:Igsf10	UTSW	3	59,331,705 (GRCm38)	missense	probably damaging	1.00
Z1088:Igsf10	UTSW	3	59,329,938 (GRCm38)	missense	possibly damaging	0.59
Z1177:Igsf10	UTSW	3	59,329,605 (GRCm38)	nonsense	probably null

Predicted Primers

PCR Primer
(F):5'- GAAGGCTTTTGGATACTACAGATCAC -3'
(R):5'- GCTGTTTTGAGTCCTAGTGAAAAC -3'

Sequencing Primer
(F):5'- TGGATACTACAGATCACATTGGCC -3'
(R):5'- GTTTTGAGTCCTAGTGAAAACACTTC -3'

Posted On

2018-10-18