Incidental Mutation 'R6823:Plekha5'
| ID |
537725 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Plekha5
|
| Ensembl Gene |
ENSMUSG00000030231 |
| Gene Name |
pleckstrin homology domain containing, family A member 5 |
| Synonyms |
2810431N21Rik, PEPP2 |
| MMRRC Submission |
044935-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.147)
|
| Stock # |
R6823 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
6 |
| Chromosomal Location |
140369780-140542836 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 140471584 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Serine to Proline
at position 112
(S112P)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000145478
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000087622]
[ENSMUST00000203517]
[ENSMUST00000203774]
[ENSMUST00000204145]
[ENSMUST00000204876]
|
| AlphaFold |
E9Q6H8 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000087622
AA Change: S112P
PolyPhen 2
Score 0.037 (Sensitivity: 0.94; Specificity: 0.82)
|
| SMART Domains |
Protein: ENSMUSP00000084904
Gene: ENSMUSG00000030231
AA Change: S112P
| Domain | Start | End | E-Value | Type |
|---|
|
WW
|
12 |
44 |
1.51e-3 |
SMART |
|
WW
|
58 |
90 |
2.17e-4 |
SMART |
|
PH
|
171 |
271 |
1.85e-17 |
SMART |
|
Blast:PH
|
592 |
715 |
7e-39 |
BLAST |
|
coiled coil region
|
747 |
781 |
N/A |
INTRINSIC |
|
low complexity region
|
896 |
916 |
N/A |
INTRINSIC |
|
low complexity region
|
924 |
938 |
N/A |
INTRINSIC |
|
low complexity region
|
1206 |
1224 |
N/A |
INTRINSIC |
|
low complexity region
|
1243 |
1258 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000203517
AA Change: S112P
PolyPhen 2
Score 0.158 (Sensitivity: 0.92; Specificity: 0.87)
|
| SMART Domains |
Protein: ENSMUSP00000145478
Gene: ENSMUSG00000030231
AA Change: S112P
| Domain | Start | End | E-Value | Type |
|---|
|
WW
|
12 |
44 |
9e-6 |
SMART |
|
WW
|
58 |
90 |
1.3e-6 |
SMART |
|
PH
|
171 |
271 |
8.6e-20 |
SMART |
|
Blast:PH
|
586 |
697 |
3e-15 |
BLAST |
|
coiled coil region
|
702 |
736 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000203774
AA Change: S3P
PolyPhen 2
Score 0.008 (Sensitivity: 0.96; Specificity: 0.76)
|
| SMART Domains |
Protein: ENSMUSP00000144832
Gene: ENSMUSG00000030231
AA Change: S3P
| Domain | Start | End | E-Value | Type |
|---|
|
PH
|
62 |
162 |
8.6e-20 |
SMART |
|
Blast:PH
|
477 |
511 |
4e-8 |
BLAST |
|
low complexity region
|
512 |
521 |
N/A |
INTRINSIC |
|
| Predicted Effect |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000204145
AA Change: S112P
PolyPhen 2
Score 0.005 (Sensitivity: 0.97; Specificity: 0.74)
|
| SMART Domains |
Protein: ENSMUSP00000145457
Gene: ENSMUSG00000030231
AA Change: S112P
| Domain | Start | End | E-Value | Type |
|---|
|
WW
|
12 |
44 |
9e-6 |
SMART |
|
WW
|
58 |
90 |
1.3e-6 |
SMART |
|
Blast:PH
|
114 |
151 |
6e-14 |
BLAST |
|
PDB:2DKP|A
|
163 |
196 |
1e-5 |
PDB |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000204876
AA Change: S3P
PolyPhen 2
Score 0.002 (Sensitivity: 0.99; Specificity: 0.30)
|
| SMART Domains |
Protein: ENSMUSP00000145336
Gene: ENSMUSG00000030231
AA Change: S3P
| Domain | Start | End | E-Value | Type |
|---|
|
PH
|
62 |
162 |
8.6e-20 |
SMART |
|
Blast:PH
|
483 |
517 |
3e-8 |
BLAST |
|
low complexity region
|
518 |
527 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.5%
- 20x: 98.4%
|
| Validation Efficiency |
98% (81/83) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 81 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Adcy8 |
T |
G |
15: 64,626,735 (GRCm39) |
|
probably null |
Het |
| Adgrv1 |
A |
G |
13: 81,705,200 (GRCm39) |
F1537L |
probably damaging |
Het |
| Aggf1 |
T |
C |
13: 95,501,231 (GRCm39) |
S384G |
probably benign |
Het |
| Anxa8 |
A |
T |
14: 33,816,722 (GRCm39) |
D204V |
possibly damaging |
Het |
| Asap3 |
A |
T |
4: 135,954,883 (GRCm39) |
E71V |
possibly damaging |
Het |
| BC024139 |
T |
C |
15: 76,003,946 (GRCm39) |
*773W |
probably null |
Het |
| Bckdhb |
T |
C |
9: 83,835,814 (GRCm39) |
V106A |
possibly damaging |
Het |
| Cep250 |
A |
G |
2: 155,823,379 (GRCm39) |
D1010G |
probably benign |
Het |
| Chrd |
T |
A |
16: 20,553,486 (GRCm39) |
L243Q |
probably damaging |
Het |
| Cib2 |
G |
T |
9: 54,457,175 (GRCm39) |
L30I |
possibly damaging |
Het |
| Cpsf7 |
T |
A |
19: 10,510,248 (GRCm39) |
L113* |
probably null |
Het |
| Cubn |
T |
A |
2: 13,449,840 (GRCm39) |
I895L |
probably benign |
Het |
| Cyp24a1 |
C |
A |
2: 170,329,899 (GRCm39) |
R351I |
probably benign |
Het |
| Cyp2a12 |
A |
T |
7: 26,733,581 (GRCm39) |
D320V |
possibly damaging |
Het |
| Dact1 |
C |
G |
12: 71,364,713 (GRCm39) |
P498R |
probably benign |
Het |
| Diaph1 |
T |
A |
18: 38,009,436 (GRCm39) |
|
probably null |
Het |
| Dnah7a |
A |
T |
1: 53,495,863 (GRCm39) |
I3198N |
probably benign |
Het |
| Dop1b |
A |
T |
16: 93,552,373 (GRCm39) |
I271F |
possibly damaging |
Het |
| Elp1 |
A |
G |
4: 56,787,939 (GRCm39) |
Y331H |
probably damaging |
Het |
| Erich3 |
C |
A |
3: 154,433,074 (GRCm39) |
F349L |
probably damaging |
Het |
| Fam187b |
G |
C |
7: 30,688,715 (GRCm39) |
V358L |
probably benign |
Het |
| Fat4 |
T |
A |
3: 39,038,088 (GRCm39) |
H3913Q |
probably benign |
Het |
| Fbxw7 |
G |
C |
3: 84,865,934 (GRCm39) |
E118D |
probably benign |
Het |
| Fgf1 |
A |
G |
18: 38,980,161 (GRCm39) |
I71T |
probably damaging |
Het |
| Fryl |
A |
T |
5: 73,222,560 (GRCm39) |
I2007K |
probably damaging |
Het |
| Galnt2 |
C |
G |
8: 125,050,750 (GRCm39) |
P130A |
probably benign |
Het |
| H1f10 |
G |
A |
6: 87,958,284 (GRCm39) |
R19C |
probably damaging |
Het |
| Hmga2 |
A |
C |
10: 120,311,929 (GRCm39) |
S14A |
possibly damaging |
Het |
| Hoxb4 |
C |
T |
11: 96,209,480 (GRCm39) |
|
probably benign |
Het |
| Hr |
A |
T |
14: 70,802,814 (GRCm39) |
I756F |
probably damaging |
Het |
| Hspa1b |
A |
T |
17: 35,177,161 (GRCm39) |
S275T |
probably benign |
Het |
| Kcnh1 |
T |
C |
1: 192,187,597 (GRCm39) |
*99R |
probably null |
Het |
| Kit |
C |
A |
5: 75,813,309 (GRCm39) |
L864I |
probably benign |
Het |
| Klk14 |
A |
T |
7: 43,343,880 (GRCm39) |
K196* |
probably null |
Het |
| Lmod1 |
A |
G |
1: 135,252,905 (GRCm39) |
N53S |
probably damaging |
Het |
| Myh13 |
T |
C |
11: 67,246,984 (GRCm39) |
M1235T |
probably benign |
Het |
| Neurl3 |
T |
A |
1: 36,307,785 (GRCm39) |
K175* |
probably null |
Het |
| Nlgn2 |
T |
A |
11: 69,716,750 (GRCm39) |
K597M |
probably damaging |
Het |
| Npdc1 |
T |
C |
2: 25,299,121 (GRCm39) |
M306T |
probably damaging |
Het |
| Obscn |
C |
T |
11: 58,958,769 (GRCm39) |
|
probably null |
Het |
| Or1p1b |
T |
C |
11: 74,130,522 (GRCm39) |
L44P |
probably damaging |
Het |
| Or52m2 |
G |
A |
7: 102,263,693 (GRCm39) |
L168F |
probably damaging |
Het |
| Or8b49 |
T |
C |
9: 38,506,201 (GRCm39) |
I228T |
possibly damaging |
Het |
| Pbrm1 |
A |
T |
14: 30,806,747 (GRCm39) |
Y1042F |
probably damaging |
Het |
| Pclo |
T |
A |
5: 14,727,921 (GRCm39) |
|
probably benign |
Het |
| Peg10 |
CATCAGGATCCCCATCAGGATGCACATCAGGATCCACATCAGGATGCACATCAGGATC |
CATC |
6: 4,756,431 (GRCm39) |
|
probably benign |
Het |
| Phf12 |
C |
T |
11: 77,913,337 (GRCm39) |
Q430* |
probably null |
Het |
| Plaat5 |
A |
T |
19: 7,616,861 (GRCm39) |
|
probably benign |
Het |
| Pld3 |
C |
T |
7: 27,235,322 (GRCm39) |
R302H |
probably damaging |
Het |
| Pmfbp1 |
T |
A |
8: 110,256,939 (GRCm39) |
S548T |
possibly damaging |
Het |
| Ppa1 |
A |
T |
10: 61,503,382 (GRCm39) |
I220F |
probably damaging |
Het |
| Ppp2r3d |
A |
G |
9: 124,439,078 (GRCm38) |
|
probably benign |
Het |
| Psmg2 |
A |
T |
18: 67,781,927 (GRCm39) |
E164D |
possibly damaging |
Het |
| Rarb |
T |
C |
14: 16,443,824 (GRCm38) |
R155G |
probably damaging |
Het |
| Rnf215 |
T |
C |
11: 4,086,609 (GRCm39) |
L162S |
probably damaging |
Het |
| Rsf1 |
GGCG |
GGCGACGGCCGCG |
7: 97,229,113 (GRCm39) |
|
probably benign |
Het |
| Rtkn2 |
G |
A |
10: 67,862,462 (GRCm39) |
V330M |
probably damaging |
Het |
| Slc16a4 |
A |
T |
3: 107,218,814 (GRCm39) |
I472F |
probably benign |
Het |
| Snx14 |
T |
C |
9: 88,276,435 (GRCm39) |
N617D |
possibly damaging |
Het |
| Spire2 |
T |
C |
8: 124,083,466 (GRCm39) |
V150A |
probably damaging |
Het |
| Sptbn1 |
C |
A |
11: 30,064,787 (GRCm39) |
R1904M |
probably damaging |
Het |
| Swap70 |
A |
G |
7: 109,880,510 (GRCm39) |
E575G |
possibly damaging |
Het |
| Tbxas1 |
A |
T |
6: 38,896,087 (GRCm39) |
M1L |
possibly damaging |
Het |
| Tenm3 |
A |
T |
8: 48,709,872 (GRCm39) |
V1688D |
probably damaging |
Het |
| Tgfbr3 |
A |
T |
5: 107,297,780 (GRCm39) |
S207T |
probably damaging |
Het |
| Timm44 |
A |
G |
8: 4,317,282 (GRCm39) |
F248L |
probably damaging |
Het |
| Tmem161a |
T |
C |
8: 70,633,849 (GRCm39) |
L170P |
probably damaging |
Het |
| Tmem63a |
A |
T |
1: 180,788,035 (GRCm39) |
Y263F |
possibly damaging |
Het |
| Tnfsf9 |
C |
A |
17: 57,412,513 (GRCm39) |
L28I |
probably benign |
Het |
| Tph2 |
T |
A |
10: 115,010,011 (GRCm39) |
N183I |
probably benign |
Het |
| Ttyh1 |
T |
C |
7: 4,125,528 (GRCm39) |
I60T |
probably damaging |
Het |
| Ubn1 |
T |
G |
16: 4,882,411 (GRCm39) |
S48A |
probably damaging |
Het |
| Ubr5 |
T |
C |
15: 37,989,842 (GRCm39) |
N2019S |
probably benign |
Het |
| Wbp2 |
T |
C |
11: 115,977,736 (GRCm39) |
N6D |
probably benign |
Het |
| Wdr59 |
T |
A |
8: 112,185,672 (GRCm39) |
E810V |
possibly damaging |
Het |
| Wiz |
T |
C |
17: 32,579,395 (GRCm39) |
D220G |
probably damaging |
Het |
| Yipf7 |
A |
G |
5: 69,674,413 (GRCm39) |
L244P |
probably damaging |
Het |
| Zdhhc17 |
T |
C |
10: 110,790,972 (GRCm39) |
T366A |
possibly damaging |
Het |
| Zfp169 |
A |
T |
13: 48,644,472 (GRCm39) |
|
probably benign |
Het |
| Zfp707 |
C |
T |
15: 75,841,572 (GRCm39) |
|
probably benign |
Het |
| Zfp788 |
A |
G |
7: 41,298,984 (GRCm39) |
H540R |
probably damaging |
Het |
|
| Other mutations in Plekha5 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00577:Plekha5
|
APN |
6 |
140,515,822 (GRCm39) |
splice site |
probably benign |
|
|
IGL00908:Plekha5
|
APN |
6 |
140,496,656 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01346:Plekha5
|
APN |
6 |
140,480,292 (GRCm39) |
splice site |
probably benign |
|
|
IGL01380:Plekha5
|
APN |
6 |
140,516,042 (GRCm39) |
splice site |
probably benign |
|
|
IGL01406:Plekha5
|
APN |
6 |
140,518,676 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01408:Plekha5
|
APN |
6 |
140,516,042 (GRCm39) |
splice site |
probably benign |
|
|
IGL01688:Plekha5
|
APN |
6 |
140,515,115 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL01719:Plekha5
|
APN |
6 |
140,515,855 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01926:Plekha5
|
APN |
6 |
140,471,642 (GRCm39) |
missense |
probably benign |
0.12 |
|
IGL01936:Plekha5
|
APN |
6 |
140,470,621 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02326:Plekha5
|
APN |
6 |
140,529,576 (GRCm39) |
nonsense |
probably null |
|
|
IGL02544:Plekha5
|
APN |
6 |
140,535,454 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
IGL02573:Plekha5
|
APN |
6 |
140,527,742 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02704:Plekha5
|
APN |
6 |
140,489,592 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02959:Plekha5
|
APN |
6 |
140,489,904 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Doubletime
|
UTSW |
6 |
140,471,655 (GRCm39) |
nonsense |
probably null |
|
|
R0067:Plekha5
|
UTSW |
6 |
140,470,629 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0067:Plekha5
|
UTSW |
6 |
140,470,629 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0095:Plekha5
|
UTSW |
6 |
140,474,323 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0095:Plekha5
|
UTSW |
6 |
140,474,323 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0105:Plekha5
|
UTSW |
6 |
140,537,473 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R0107:Plekha5
|
UTSW |
6 |
140,537,473 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R0359:Plekha5
|
UTSW |
6 |
140,537,473 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R0360:Plekha5
|
UTSW |
6 |
140,537,473 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R0362:Plekha5
|
UTSW |
6 |
140,537,473 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R0363:Plekha5
|
UTSW |
6 |
140,537,473 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R0364:Plekha5
|
UTSW |
6 |
140,537,473 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R0365:Plekha5
|
UTSW |
6 |
140,537,473 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R0833:Plekha5
|
UTSW |
6 |
140,535,360 (GRCm39) |
splice site |
probably benign |
|
|
R0835:Plekha5
|
UTSW |
6 |
140,514,576 (GRCm39) |
nonsense |
probably null |
|
|
R0836:Plekha5
|
UTSW |
6 |
140,535,360 (GRCm39) |
splice site |
probably benign |
|
|
R0944:Plekha5
|
UTSW |
6 |
140,515,922 (GRCm39) |
splice site |
probably benign |
|
|
R2015:Plekha5
|
UTSW |
6 |
140,480,290 (GRCm39) |
critical splice donor site |
probably null |
|
|
R2043:Plekha5
|
UTSW |
6 |
140,498,530 (GRCm39) |
splice site |
probably benign |
|
|
R2086:Plekha5
|
UTSW |
6 |
140,516,044 (GRCm39) |
splice site |
probably null |
|
|
R2102:Plekha5
|
UTSW |
6 |
140,518,603 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2109:Plekha5
|
UTSW |
6 |
140,369,942 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R2135:Plekha5
|
UTSW |
6 |
140,526,225 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R2150:Plekha5
|
UTSW |
6 |
140,516,129 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2211:Plekha5
|
UTSW |
6 |
140,471,587 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R2414:Plekha5
|
UTSW |
6 |
140,496,582 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2915:Plekha5
|
UTSW |
6 |
140,534,925 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R3120:Plekha5
|
UTSW |
6 |
140,537,367 (GRCm39) |
missense |
probably benign |
0.00 |
|
R3924:Plekha5
|
UTSW |
6 |
140,516,105 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R4049:Plekha5
|
UTSW |
6 |
140,529,597 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4056:Plekha5
|
UTSW |
6 |
140,534,958 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R4077:Plekha5
|
UTSW |
6 |
140,501,647 (GRCm39) |
splice site |
probably null |
|
|
R4320:Plekha5
|
UTSW |
6 |
140,489,543 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R4343:Plekha5
|
UTSW |
6 |
140,501,780 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4359:Plekha5
|
UTSW |
6 |
140,537,414 (GRCm39) |
missense |
probably benign |
0.07 |
|
R4377:Plekha5
|
UTSW |
6 |
140,525,191 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4480:Plekha5
|
UTSW |
6 |
140,472,205 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4533:Plekha5
|
UTSW |
6 |
140,516,057 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4623:Plekha5
|
UTSW |
6 |
140,496,912 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R4672:Plekha5
|
UTSW |
6 |
140,470,655 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R4871:Plekha5
|
UTSW |
6 |
140,471,636 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4903:Plekha5
|
UTSW |
6 |
140,532,093 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5121:Plekha5
|
UTSW |
6 |
140,525,200 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5156:Plekha5
|
UTSW |
6 |
140,372,254 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5376:Plekha5
|
UTSW |
6 |
140,496,870 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5445:Plekha5
|
UTSW |
6 |
140,498,459 (GRCm39) |
nonsense |
probably null |
|
|
R5753:Plekha5
|
UTSW |
6 |
140,482,730 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R5836:Plekha5
|
UTSW |
6 |
140,372,250 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5972:Plekha5
|
UTSW |
6 |
140,518,639 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R6196:Plekha5
|
UTSW |
6 |
140,525,179 (GRCm39) |
missense |
probably benign |
0.28 |
|
R6254:Plekha5
|
UTSW |
6 |
140,532,162 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6501:Plekha5
|
UTSW |
6 |
140,471,655 (GRCm39) |
nonsense |
probably null |
|
|
R6620:Plekha5
|
UTSW |
6 |
140,518,601 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6663:Plekha5
|
UTSW |
6 |
140,523,016 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6992:Plekha5
|
UTSW |
6 |
140,489,634 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7196:Plekha5
|
UTSW |
6 |
140,489,648 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R7487:Plekha5
|
UTSW |
6 |
140,516,059 (GRCm39) |
missense |
probably benign |
0.25 |
|
R7493:Plekha5
|
UTSW |
6 |
140,526,161 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7557:Plekha5
|
UTSW |
6 |
140,372,271 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7743:Plekha5
|
UTSW |
6 |
140,501,712 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7792:Plekha5
|
UTSW |
6 |
140,534,950 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R7808:Plekha5
|
UTSW |
6 |
140,529,640 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7910:Plekha5
|
UTSW |
6 |
140,472,184 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R7944:Plekha5
|
UTSW |
6 |
140,526,201 (GRCm39) |
missense |
possibly damaging |
0.48 |
|
R7945:Plekha5
|
UTSW |
6 |
140,526,201 (GRCm39) |
missense |
possibly damaging |
0.48 |
|
R7992:Plekha5
|
UTSW |
6 |
140,472,267 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8979:Plekha5
|
UTSW |
6 |
140,496,818 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9024:Plekha5
|
UTSW |
6 |
140,370,176 (GRCm39) |
missense |
probably benign |
0.10 |
|
R9135:Plekha5
|
UTSW |
6 |
140,480,239 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9215:Plekha5
|
UTSW |
6 |
140,501,733 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R9241:Plekha5
|
UTSW |
6 |
140,525,204 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9447:Plekha5
|
UTSW |
6 |
140,525,192 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9625:Plekha5
|
UTSW |
6 |
140,372,253 (GRCm39) |
missense |
probably benign |
0.24 |
|
X0027:Plekha5
|
UTSW |
6 |
140,370,149 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- GCTCACTCATGTTAGGCTAGAATTAG -3'
(R):5'- GCTGATTCAACAGAATACCCATTC -3'
Sequencing Primer
(F):5'- GGTCACCTTTATGCCTGA -3'
(R):5'- TCAACAGAATACCCATTCCCTCATAC -3'
|
| Posted On |
2018-10-18 |
Incidental Mutation