Incidental Mutation 'R6913:Adamts16'
| ID |
539197 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Adamts16
|
| Ensembl Gene |
ENSMUSG00000049538 |
| Gene Name |
ADAM metallopeptidase with thrombospondin type 1 motif 16 |
| Synonyms |
|
| MMRRC Submission |
045034-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R6913 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
13 |
| Chromosomal Location |
70875921-70989930 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 70877017 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Phenylalanine to Serine
at position 1208
(F1208S)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000079041
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000080145]
[ENSMUST00000123552]
|
| AlphaFold |
Q69Z28 |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000080145
AA Change: F1208S
PolyPhen 2
Score 0.939 (Sensitivity: 0.80; Specificity: 0.94)
|
| SMART Domains |
Protein: ENSMUSP00000079041
Gene: ENSMUSG00000049538
AA Change: F1208S
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
20 |
N/A |
INTRINSIC |
|
low complexity region
|
26 |
36 |
N/A |
INTRINSIC |
|
Pfam:Pep_M12B_propep
|
57 |
203 |
7.8e-34 |
PFAM |
|
Pfam:Reprolysin_5
|
287 |
470 |
2.9e-13 |
PFAM |
|
Pfam:Reprolysin_4
|
289 |
489 |
1.2e-8 |
PFAM |
|
Pfam:Reprolysin
|
289 |
493 |
5.4e-32 |
PFAM |
|
Pfam:Reprolysin_2
|
306 |
483 |
3.7e-10 |
PFAM |
|
Pfam:Reprolysin_3
|
310 |
442 |
6.4e-11 |
PFAM |
|
TSP1
|
587 |
639 |
1.43e-14 |
SMART |
|
Pfam:ADAM_spacer1
|
744 |
856 |
1.3e-37 |
PFAM |
|
TSP1
|
872 |
926 |
3.48e0 |
SMART |
|
TSP1
|
928 |
985 |
4.84e-3 |
SMART |
|
TSP1
|
987 |
1046 |
1.49e-3 |
SMART |
|
TSP1
|
1052 |
1113 |
3.19e-2 |
SMART |
|
TSP1
|
1127 |
1179 |
7.68e-6 |
SMART |
|
Pfam:PLAC
|
1188 |
1218 |
2.9e-13 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000123552
|
| SMART Domains |
Protein: ENSMUSP00000122031
Gene: ENSMUSG00000049538
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
20 |
N/A |
INTRINSIC |
|
low complexity region
|
26 |
36 |
N/A |
INTRINSIC |
|
Pfam:Pep_M12B_propep
|
56 |
203 |
5.9e-33 |
PFAM |
|
Pfam:Reprolysin_5
|
287 |
470 |
5.1e-14 |
PFAM |
|
Pfam:Reprolysin_4
|
289 |
489 |
2.2e-9 |
PFAM |
|
Pfam:Reprolysin
|
289 |
493 |
1.2e-33 |
PFAM |
|
Pfam:Reprolysin_2
|
306 |
483 |
1.2e-10 |
PFAM |
|
Pfam:Reprolysin_3
|
310 |
442 |
9.7e-11 |
PFAM |
|
TSP1
|
587 |
639 |
1.43e-14 |
SMART |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.1%
- 20x: 96.9%
|
| Validation Efficiency |
97% (74/76) |
| MGI Phenotype |
FUNCTION: This gene encodes a member of "a disintegrin and metalloproteinase with thrombospondin motifs" (ADAMTS) family of multi-domain matrix-associated metalloendopeptidases that have diverse roles in tissue morphogenesis and pathophysiological remodeling, in inflammation and in vascular biology. This gene is co-expressed with the Wilms tumor protein, Wt1, in the developing glomeruli of embryonic kidneys. The encoded preproprotein undergoes proteolytic processing to generate an active enzyme. [provided by RefSeq, Jul 2016]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 76 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abcc5 |
A |
T |
16: 20,197,494 (GRCm39) |
I619N |
possibly damaging |
Het |
| Accsl |
T |
C |
2: 93,696,488 (GRCm39) |
K41E |
possibly damaging |
Het |
| Actr6 |
T |
C |
10: 89,562,558 (GRCm39) |
E107G |
probably damaging |
Het |
| Adam7 |
T |
A |
14: 68,771,100 (GRCm39) |
M9L |
probably benign |
Het |
| Adamts12 |
T |
A |
15: 11,215,778 (GRCm39) |
H266Q |
probably damaging |
Het |
| Ankrd11 |
T |
C |
8: 123,621,650 (GRCm39) |
D734G |
probably benign |
Het |
| Ap1b1 |
T |
C |
11: 4,962,972 (GRCm39) |
V43A |
possibly damaging |
Het |
| Asnsd1 |
A |
G |
1: 53,387,390 (GRCm39) |
V79A |
probably damaging |
Het |
| Aste1 |
T |
A |
9: 105,274,607 (GRCm39) |
S221R |
probably benign |
Het |
| Ccndbp1 |
G |
A |
2: 120,840,347 (GRCm39) |
E94K |
probably benign |
Het |
| Cdc34 |
G |
A |
10: 79,520,937 (GRCm39) |
|
probably null |
Het |
| Cdh16 |
T |
C |
8: 105,348,896 (GRCm39) |
D67G |
probably benign |
Het |
| Chd8 |
T |
C |
14: 52,451,951 (GRCm39) |
E1348G |
probably damaging |
Het |
| Chl1 |
C |
T |
6: 103,642,909 (GRCm39) |
Q216* |
probably null |
Het |
| Cse1l |
G |
A |
2: 166,771,797 (GRCm39) |
V353I |
possibly damaging |
Het |
| Ctbp2 |
G |
A |
7: 132,616,455 (GRCm39) |
S160F |
possibly damaging |
Het |
| Cyp1a1 |
C |
A |
9: 57,607,576 (GRCm39) |
T68K |
probably damaging |
Het |
| Dennd11 |
T |
C |
6: 40,383,851 (GRCm39) |
N397S |
possibly damaging |
Het |
| Dlgap2 |
T |
A |
8: 14,828,374 (GRCm39) |
M594K |
probably benign |
Het |
| Dnah6 |
C |
T |
6: 73,189,505 (GRCm39) |
E48K |
probably benign |
Het |
| Dock2 |
A |
G |
11: 34,647,049 (GRCm39) |
V35A |
probably damaging |
Het |
| Edem2 |
A |
T |
2: 155,568,594 (GRCm39) |
S73R |
probably damaging |
Het |
| Eps15 |
T |
C |
4: 109,218,427 (GRCm39) |
V430A |
probably benign |
Het |
| Frem2 |
T |
C |
3: 53,424,242 (GRCm39) |
N3065S |
probably damaging |
Het |
| Gal3st4 |
A |
T |
5: 138,269,090 (GRCm39) |
S123R |
possibly damaging |
Het |
| Garnl3 |
T |
A |
2: 32,876,841 (GRCm39) |
I937F |
possibly damaging |
Het |
| Gfod2 |
C |
T |
8: 106,443,995 (GRCm39) |
V183M |
possibly damaging |
Het |
| Glipr1l1 |
T |
C |
10: 111,898,339 (GRCm39) |
|
probably null |
Het |
| Gm7145 |
T |
G |
1: 117,913,711 (GRCm39) |
C198G |
probably damaging |
Het |
| Gvin2 |
G |
A |
7: 105,551,187 (GRCm39) |
Q622* |
probably null |
Het |
| H2-Eb2 |
G |
A |
17: 34,552,523 (GRCm39) |
A123T |
possibly damaging |
Het |
| Ighv1-55 |
T |
C |
12: 115,172,129 (GRCm39) |
I7V |
probably benign |
Het |
| Itpripl2 |
G |
T |
7: 118,090,332 (GRCm39) |
P76T |
possibly damaging |
Het |
| Kat6a |
C |
A |
8: 23,393,215 (GRCm39) |
A231E |
possibly damaging |
Het |
| Lipo3 |
C |
T |
19: 33,757,705 (GRCm39) |
V255I |
probably benign |
Het |
| Mamstr |
A |
T |
7: 45,292,662 (GRCm39) |
M141L |
probably benign |
Het |
| Med13 |
A |
G |
11: 86,210,702 (GRCm39) |
V480A |
probably benign |
Het |
| Mei1 |
A |
G |
15: 81,973,810 (GRCm39) |
N523S |
probably benign |
Het |
| Mill2 |
A |
G |
7: 18,590,351 (GRCm39) |
T144A |
probably null |
Het |
| Muc16 |
C |
A |
9: 18,553,959 (GRCm39) |
L4111F |
unknown |
Het |
| Mylk2 |
G |
A |
2: 152,755,610 (GRCm39) |
G258E |
possibly damaging |
Het |
| Myom2 |
T |
G |
8: 15,115,710 (GRCm39) |
S42A |
probably benign |
Het |
| Nab1 |
C |
A |
1: 52,503,995 (GRCm39) |
G401C |
possibly damaging |
Het |
| Nifk |
T |
C |
1: 118,260,592 (GRCm39) |
V244A |
possibly damaging |
Het |
| Nipsnap2 |
C |
A |
5: 129,830,357 (GRCm39) |
Q224K |
probably benign |
Het |
| Nop16 |
T |
G |
13: 54,737,553 (GRCm39) |
K47Q |
probably damaging |
Het |
| Nup153 |
A |
T |
13: 46,853,192 (GRCm39) |
S548R |
probably damaging |
Het |
| Or2at1 |
A |
C |
7: 99,416,924 (GRCm39) |
D185A |
probably damaging |
Het |
| Or4g17 |
A |
G |
2: 111,209,347 (GRCm39) |
M1V |
probably null |
Het |
| Or5b111 |
A |
G |
19: 13,290,998 (GRCm39) |
I217T |
probably benign |
Het |
| Pard6g |
G |
A |
18: 80,160,534 (GRCm39) |
V216I |
possibly damaging |
Het |
| Pcdh20 |
C |
T |
14: 88,706,038 (GRCm39) |
V421I |
probably benign |
Het |
| Pcif1 |
G |
A |
2: 164,726,224 (GRCm39) |
|
probably null |
Het |
| Pde11a |
C |
A |
2: 76,168,084 (GRCm39) |
V290F |
probably damaging |
Het |
| Pisd |
T |
C |
5: 32,894,773 (GRCm39) |
Y511C |
probably damaging |
Het |
| Polg |
A |
T |
7: 79,110,405 (GRCm39) |
D276E |
probably damaging |
Het |
| Polr3b |
T |
C |
10: 84,549,496 (GRCm39) |
V906A |
probably damaging |
Het |
| Prkcg |
C |
T |
7: 3,362,335 (GRCm39) |
P270S |
probably benign |
Het |
| Rapgef2 |
T |
A |
3: 78,993,281 (GRCm39) |
I884F |
probably damaging |
Het |
| Rpl13 |
C |
A |
8: 123,830,014 (GRCm39) |
N113K |
possibly damaging |
Het |
| Rxra |
T |
A |
2: 27,631,186 (GRCm39) |
I139N |
probably damaging |
Het |
| Sf3b5 |
T |
A |
10: 12,884,487 (GRCm39) |
C41S |
probably benign |
Het |
| Spata31e3 |
G |
T |
13: 50,399,293 (GRCm39) |
P1011H |
probably damaging |
Het |
| Stk24 |
C |
T |
14: 121,540,221 (GRCm39) |
R126Q |
probably damaging |
Het |
| Taar8b |
T |
C |
10: 23,967,963 (GRCm39) |
D77G |
possibly damaging |
Het |
| Tbc1d1 |
T |
A |
5: 64,468,452 (GRCm39) |
C566S |
probably benign |
Het |
| Tenm3 |
A |
T |
8: 48,751,972 (GRCm39) |
M948K |
probably damaging |
Het |
| Thbs4 |
T |
A |
13: 92,894,444 (GRCm39) |
Q693L |
possibly damaging |
Het |
| Tnfrsf26 |
A |
T |
7: 143,172,126 (GRCm39) |
C61* |
probably null |
Het |
| Trp63 |
A |
G |
16: 25,707,918 (GRCm39) |
E636G |
probably damaging |
Het |
| Try5 |
T |
C |
6: 41,288,266 (GRCm39) |
Y121C |
probably damaging |
Het |
| Ttn |
G |
T |
2: 76,660,755 (GRCm39) |
|
probably benign |
Het |
| Vamp1 |
T |
A |
6: 125,195,908 (GRCm39) |
V55D |
probably damaging |
Het |
| Vmn2r117 |
T |
C |
17: 23,698,537 (GRCm39) |
N12S |
probably damaging |
Het |
| Vmn2r90 |
G |
A |
17: 17,924,323 (GRCm39) |
G41S |
probably damaging |
Het |
| Zfp462 |
T |
A |
4: 55,007,775 (GRCm39) |
D71E |
probably benign |
Het |
|
| Other mutations in Adamts16 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01024:Adamts16
|
APN |
13 |
70,943,603 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL01338:Adamts16
|
APN |
13 |
70,984,234 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01663:Adamts16
|
APN |
13 |
70,941,260 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL01804:Adamts16
|
APN |
13 |
70,949,080 (GRCm39) |
nonsense |
probably null |
|
|
IGL01874:Adamts16
|
APN |
13 |
70,916,823 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
IGL01984:Adamts16
|
APN |
13 |
70,935,266 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02305:Adamts16
|
APN |
13 |
70,921,048 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02350:Adamts16
|
APN |
13 |
70,886,704 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02357:Adamts16
|
APN |
13 |
70,886,704 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02429:Adamts16
|
APN |
13 |
70,935,289 (GRCm39) |
splice site |
probably benign |
|
|
IGL02450:Adamts16
|
APN |
13 |
70,984,419 (GRCm39) |
missense |
probably damaging |
0.97 |
|
IGL02807:Adamts16
|
APN |
13 |
70,886,897 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL03356:Adamts16
|
APN |
13 |
70,901,410 (GRCm39) |
missense |
probably benign |
0.00 |
|
swap
|
UTSW |
13 |
70,927,637 (GRCm39) |
critical splice donor site |
probably benign |
|
|
switcheroo
|
UTSW |
13 |
70,949,073 (GRCm39) |
missense |
probably benign |
|
|
R0046:Adamts16
|
UTSW |
13 |
70,911,579 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0046:Adamts16
|
UTSW |
13 |
70,911,579 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0201:Adamts16
|
UTSW |
13 |
70,927,763 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R0326:Adamts16
|
UTSW |
13 |
70,927,730 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R0336:Adamts16
|
UTSW |
13 |
70,939,913 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R0369:Adamts16
|
UTSW |
13 |
70,927,671 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R0422:Adamts16
|
UTSW |
13 |
70,887,074 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0507:Adamts16
|
UTSW |
13 |
70,916,766 (GRCm39) |
missense |
probably benign |
|
|
R0524:Adamts16
|
UTSW |
13 |
70,949,013 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0590:Adamts16
|
UTSW |
13 |
70,949,073 (GRCm39) |
missense |
probably benign |
|
|
R0734:Adamts16
|
UTSW |
13 |
70,886,600 (GRCm39) |
splice site |
probably benign |
|
|
R0787:Adamts16
|
UTSW |
13 |
70,886,948 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0826:Adamts16
|
UTSW |
13 |
70,916,811 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
R0920:Adamts16
|
UTSW |
13 |
70,911,680 (GRCm39) |
splice site |
probably benign |
|
|
R1027:Adamts16
|
UTSW |
13 |
70,915,921 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1462:Adamts16
|
UTSW |
13 |
70,984,253 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1462:Adamts16
|
UTSW |
13 |
70,984,253 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1535:Adamts16
|
UTSW |
13 |
70,939,913 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1617:Adamts16
|
UTSW |
13 |
70,946,154 (GRCm39) |
missense |
probably benign |
0.09 |
|
R1700:Adamts16
|
UTSW |
13 |
70,927,637 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R1734:Adamts16
|
UTSW |
13 |
70,927,637 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R1736:Adamts16
|
UTSW |
13 |
70,927,637 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R1737:Adamts16
|
UTSW |
13 |
70,927,637 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R1738:Adamts16
|
UTSW |
13 |
70,927,637 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R1746:Adamts16
|
UTSW |
13 |
70,927,717 (GRCm39) |
splice site |
probably null |
|
|
R1869:Adamts16
|
UTSW |
13 |
70,883,866 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1944:Adamts16
|
UTSW |
13 |
70,940,005 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R1997:Adamts16
|
UTSW |
13 |
70,901,386 (GRCm39) |
missense |
probably benign |
0.39 |
|
R2018:Adamts16
|
UTSW |
13 |
70,927,637 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R2135:Adamts16
|
UTSW |
13 |
70,949,126 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2219:Adamts16
|
UTSW |
13 |
70,927,637 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R2228:Adamts16
|
UTSW |
13 |
70,927,637 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R3410:Adamts16
|
UTSW |
13 |
70,901,345 (GRCm39) |
missense |
probably benign |
0.00 |
|
R3411:Adamts16
|
UTSW |
13 |
70,901,345 (GRCm39) |
missense |
probably benign |
0.00 |
|
R3842:Adamts16
|
UTSW |
13 |
70,887,010 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R4117:Adamts16
|
UTSW |
13 |
70,916,111 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4435:Adamts16
|
UTSW |
13 |
70,927,637 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R4436:Adamts16
|
UTSW |
13 |
70,927,637 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R4526:Adamts16
|
UTSW |
13 |
70,927,637 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R4552:Adamts16
|
UTSW |
13 |
70,927,637 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R4555:Adamts16
|
UTSW |
13 |
70,927,637 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R4556:Adamts16
|
UTSW |
13 |
70,927,637 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R4557:Adamts16
|
UTSW |
13 |
70,927,637 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R4579:Adamts16
|
UTSW |
13 |
70,927,743 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4639:Adamts16
|
UTSW |
13 |
70,927,637 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R4640:Adamts16
|
UTSW |
13 |
70,927,637 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R4641:Adamts16
|
UTSW |
13 |
70,927,637 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R4642:Adamts16
|
UTSW |
13 |
70,927,637 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R4672:Adamts16
|
UTSW |
13 |
70,927,637 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R5350:Adamts16
|
UTSW |
13 |
70,901,315 (GRCm39) |
nonsense |
probably null |
|
|
R5464:Adamts16
|
UTSW |
13 |
70,909,868 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5613:Adamts16
|
UTSW |
13 |
70,878,253 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5667:Adamts16
|
UTSW |
13 |
70,984,494 (GRCm39) |
nonsense |
probably null |
|
|
R5735:Adamts16
|
UTSW |
13 |
70,984,337 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R5762:Adamts16
|
UTSW |
13 |
70,886,617 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5907:Adamts16
|
UTSW |
13 |
70,877,029 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6169:Adamts16
|
UTSW |
13 |
70,918,393 (GRCm39) |
nonsense |
probably null |
|
|
R6351:Adamts16
|
UTSW |
13 |
70,984,322 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6665:Adamts16
|
UTSW |
13 |
70,927,689 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6982:Adamts16
|
UTSW |
13 |
70,916,639 (GRCm39) |
splice site |
probably null |
|
|
R6996:Adamts16
|
UTSW |
13 |
70,946,157 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R7313:Adamts16
|
UTSW |
13 |
70,921,074 (GRCm39) |
nonsense |
probably null |
|
|
R7356:Adamts16
|
UTSW |
13 |
70,984,399 (GRCm39) |
missense |
probably benign |
0.03 |
|
R7509:Adamts16
|
UTSW |
13 |
70,935,283 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7595:Adamts16
|
UTSW |
13 |
70,878,234 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7782:Adamts16
|
UTSW |
13 |
70,984,265 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R7968:Adamts16
|
UTSW |
13 |
70,886,701 (GRCm39) |
missense |
probably benign |
|
|
R8231:Adamts16
|
UTSW |
13 |
70,925,599 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8232:Adamts16
|
UTSW |
13 |
70,941,217 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8470:Adamts16
|
UTSW |
13 |
70,984,496 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8485:Adamts16
|
UTSW |
13 |
70,886,794 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R8772:Adamts16
|
UTSW |
13 |
70,984,453 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8916:Adamts16
|
UTSW |
13 |
70,941,307 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8921:Adamts16
|
UTSW |
13 |
70,939,910 (GRCm39) |
splice site |
probably benign |
|
|
R8973:Adamts16
|
UTSW |
13 |
70,886,959 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9132:Adamts16
|
UTSW |
13 |
70,901,408 (GRCm39) |
missense |
probably benign |
0.39 |
|
R9149:Adamts16
|
UTSW |
13 |
70,883,948 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9159:Adamts16
|
UTSW |
13 |
70,901,408 (GRCm39) |
missense |
probably benign |
0.39 |
|
R9312:Adamts16
|
UTSW |
13 |
70,949,045 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9584:Adamts16
|
UTSW |
13 |
70,949,136 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1176:Adamts16
|
UTSW |
13 |
70,909,892 (GRCm39) |
missense |
probably benign |
|
|
| Predicted Primers |
PCR Primer
(F):5'- GGATCCACTCTAGGTCAAAAGAC -3'
(R):5'- TGCAAGGCCCCTTTAACAGC -3'
Sequencing Primer
(F):5'- TCTAGGTCAAAAGACCCACAGTC -3'
(R):5'- AGCCTCAAGACCCACATTTTCTAGTG -3'
|
| Posted On |
2018-11-06 |
Incidental Mutation