Incidental Mutation 'IGL01024:Tmem171'
ID53950
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Tmem171
Ensembl Gene ENSMUSG00000052485
Gene Nametransmembrane protein 171
SynonymsLOC380863
Accession Numbers
Is this an essential gene? Non essential (E-score: 0.000) question?
Stock #IGL01024
Quality Score
Status
Chromosome13
Chromosomal Location98686235-98694834 bp(-) (GRCm38)
Type of Mutationcritical splice acceptor site
DNA Base Change (assembly) T to A at 98686518 bp
ZygosityHeterozygous
Amino Acid Change
Ref Sequence ENSEMBL: ENSMUSP00000070369 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000064347] [ENSMUST00000064347]
Predicted Effect probably null
Transcript: ENSMUST00000064347
SMART Domains Protein: ENSMUSP00000070369
Gene: ENSMUSG00000052485

DomainStartEndE-ValueType
Pfam:TMEM171 2 317 3e-168 PFAM
Predicted Effect probably null
Transcript: ENSMUST00000064347
SMART Domains Protein: ENSMUSP00000070369
Gene: ENSMUSG00000052485

DomainStartEndE-ValueType
Pfam:TMEM171 2 317 3e-168 PFAM
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 51 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
1810055G02Rik T C 19: 3,717,040 V209A probably benign Het
Abca6 T A 11: 110,197,142 Y1053F probably benign Het
Acot12 C T 13: 91,781,211 Q386* probably null Het
Adamts16 A G 13: 70,795,484 V336A probably benign Het
Ankrd49 A G 9: 14,782,803 F23L probably damaging Het
Aspm A T 1: 139,478,124 H1583L possibly damaging Het
Atp6v0a1 A G 11: 101,048,439 I677V probably benign Het
BC005561 T G 5: 104,521,746 V1378G probably benign Het
Brinp1 A T 4: 68,762,494 W600R probably damaging Het
C87977 A T 4: 144,208,475 I232K possibly damaging Het
Ccdc185 T C 1: 182,747,423 E567G possibly damaging Het
Clip2 T C 5: 134,510,212 D445G probably damaging Het
Elp5 T C 11: 69,968,422 probably benign Het
Gm9376 A G 14: 118,267,158 M1V probably null Het
Gtf2a1l A G 17: 88,671,291 K40R probably damaging Het
Hdc A G 2: 126,603,846 V246A probably benign Het
Hectd2 T A 19: 36,606,393 F479L probably damaging Het
Hipk1 G T 3: 103,760,636 N538K probably benign Het
Kif27 T A 13: 58,288,201 E1259D possibly damaging Het
Klhdc2 T A 12: 69,305,836 N256K probably benign Het
Krt71 C T 15: 101,736,674 A401T probably damaging Het
Mapk3 A T 7: 126,764,774 K312* probably null Het
Med12l G T 3: 59,073,341 S365I probably damaging Het
Mgam A G 6: 40,643,010 K11R probably benign Het
Nox3 A T 17: 3,683,015 I187N probably damaging Het
Nudcd1 T A 15: 44,420,826 M55L probably benign Het
Olfr1312 A T 2: 112,042,371 F220L probably benign Het
Olfr43 A T 11: 74,206,655 L187Q probably damaging Het
Olfr983 A G 9: 40,092,733 S78P probably damaging Het
Pard6g T C 18: 80,079,822 probably benign Het
Pbrm1 G A 14: 31,052,260 R461H probably damaging Het
Ppm1f C A 16: 16,923,769 T369K probably benign Het
Ppp1r16b C T 2: 158,740,816 probably benign Het
Prom2 T C 2: 127,541,139 N61S probably benign Het
Psmc2 T C 5: 21,801,198 probably benign Het
Psme2 A G 14: 55,588,436 probably benign Het
Ptprc T C 1: 138,080,912 H655R probably damaging Het
Pxdn A C 12: 29,987,099 N292T probably damaging Het
Rapgef2 T C 3: 79,070,138 I1301V probably benign Het
Rnase11 T C 14: 51,049,864 I78V probably benign Het
Rpl41 A G 10: 128,548,377 probably benign Het
Sgf29 G A 7: 126,664,931 R56Q possibly damaging Het
Sis A G 3: 72,911,876 L1449S probably damaging Het
Slc34a2 T A 5: 53,067,630 V371D possibly damaging Het
Son C A 16: 91,655,910 T515K probably damaging Het
Tbx15 A T 3: 99,316,246 D250V probably damaging Het
Ugt2b36 C T 5: 87,080,869 probably null Het
Vill G A 9: 119,070,350 probably null Het
Vmn2r22 A G 6: 123,638,053 F193L probably damaging Het
Vmn2r95 C T 17: 18,452,328 probably benign Het
Vstm2a T A 11: 16,281,874 V223D possibly damaging Het
Other mutations in Tmem171
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL00756:Tmem171 APN 13 98686426 missense probably benign
IGL01584:Tmem171 APN 13 98692175 unclassified probably null
R0366:Tmem171 UTSW 13 98692228 missense possibly damaging 0.92
R0380:Tmem171 UTSW 13 98692027 missense possibly damaging 0.75
R1903:Tmem171 UTSW 13 98686416 nonsense probably null
R2023:Tmem171 UTSW 13 98692225 missense probably damaging 0.97
R2102:Tmem171 UTSW 13 98692343 missense probably damaging 1.00
R4090:Tmem171 UTSW 13 98692588 missense probably damaging 0.99
R4941:Tmem171 UTSW 13 98692295 missense possibly damaging 0.92
R5341:Tmem171 UTSW 13 98688448 missense probably damaging 1.00
R5654:Tmem171 UTSW 13 98692066 missense probably benign 0.12
R5741:Tmem171 UTSW 13 98692051 missense probably benign
R5761:Tmem171 UTSW 13 98692511 missense probably damaging 1.00
R6725:Tmem171 UTSW 13 98692170 nonsense probably null
R6947:Tmem171 UTSW 13 98688442 missense possibly damaging 0.92
R6981:Tmem171 UTSW 13 98692468 missense possibly damaging 0.92
R7171:Tmem171 UTSW 13 98692236 nonsense probably null
R7229:Tmem171 UTSW 13 98692625 missense probably benign 0.23
R7447:Tmem171 UTSW 13 98688354 missense probably benign 0.01
Posted On2013-06-28