Incidental Mutation 'IGL01010:Gm3573'
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Gm3573
Ensembl Gene ENSMUSG00000091792
Gene Namepredicted gene 3573
Accession Numbers
Is this an essential gene? Not available question?
Stock #IGL01010
Quality Score
Chromosomal Location42185391-42190791 bp(-) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) T to A at 42187566 bp
Amino Acid Change Isoleucine to Leucine at position 141 (I141L)
Ref Sequence ENSEMBL: ENSMUSP00000127488 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000168673]
Predicted Effect probably benign
Transcript: ENSMUST00000168673
AA Change: I141L

PolyPhen 2 Score 0.083 (Sensitivity: 0.93; Specificity: 0.85)
SMART Domains Protein: ENSMUSP00000127488
Gene: ENSMUSG00000091792
AA Change: I141L

Pfam:Takusan 10 88 1.4e-20 PFAM
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 26 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
1700030K09Rik C A 8: 72,445,215 S155R probably damaging Het
Acss3 G T 10: 107,023,849 probably benign Het
Ano4 G A 10: 88,960,600 T680I probably benign Het
Drosha C T 15: 12,827,289 probably benign Het
Ehd3 A G 17: 73,827,489 D281G probably damaging Het
Exoc5 A G 14: 49,037,755 L196P probably damaging Het
Gal3st1 T C 11: 3,996,914 probably benign Het
Gart G A 16: 91,643,092 R4* probably null Het
Gm21738 T A 14: 19,417,361 T56S probably benign Het
Gpr6 A G 10: 41,071,151 M145T probably benign Het
Kcns3 T C 12: 11,092,426 M91V probably benign Het
Marc2 T G 1: 184,819,316 I308L probably benign Het
Mto1 A G 9: 78,461,643 K529R probably benign Het
Naip2 A T 13: 100,154,938 V1164D probably damaging Het
Olfr1053 A T 2: 86,314,944 I114N probably damaging Het
Olfr695 T C 7: 106,874,253 probably benign Het
Plekha1 T C 7: 130,902,254 probably benign Het
Psg26 T C 7: 18,478,330 S367G possibly damaging Het
Rps6kb1 T C 11: 86,502,766 M513V probably benign Het
Slitrk3 C T 3: 73,049,273 G722D probably benign Het
Sssca1 A G 19: 5,731,265 S78P probably damaging Het
Stag1 A G 9: 100,945,933 E1005G probably benign Het
Tgfbr2 A T 9: 116,129,980 L122Q possibly damaging Het
Traf2 G A 2: 25,520,438 R400* probably null Het
Trim33 C T 3: 103,346,715 Q153* probably null Het
Zmynd15 T C 11: 70,465,916 Y551H probably damaging Het
Other mutations in Gm3573
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL02548:Gm3573 APN 14 42187495 critical splice donor site probably null
R6774:Gm3573 UTSW 14 42187515 missense possibly damaging 0.86
R6827:Gm3573 UTSW 14 42188472 missense probably benign 0.00
R7607:Gm3573 UTSW 14 42189750 missense probably benign 0.18
Posted On2013-06-28