Incidental Mutation 'IGL01021:Gm3278'
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Gm3278
Ensembl Gene ENSMUSG00000091185
Gene Namepredicted gene 3278
Accession Numbers
Is this an essential gene? Not available question?
Stock #IGL01021
Quality Score
Chromosomal Location4892416-4902431 bp(+) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) G to T at 4895222 bp
Amino Acid Change Valine to Leucine at position 159 (V159L)
Ref Sequence ENSEMBL: ENSMUSP00000131885 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000164459]
Predicted Effect possibly damaging
Transcript: ENSMUST00000164459
AA Change: V159L

PolyPhen 2 Score 0.598 (Sensitivity: 0.87; Specificity: 0.91)
SMART Domains Protein: ENSMUSP00000131885
Gene: ENSMUSG00000091185
AA Change: V159L

Pfam:Takusan 48 128 7.2e-21 PFAM
Predicted Effect noncoding transcript
Transcript: ENSMUST00000181157
Predicted Effect noncoding transcript
Transcript: ENSMUST00000181364
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 33 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
4930533L02Rik T C 7: 125,318,676 V80A unknown Het
Adam28 A G 14: 68,642,114 S162P probably benign Het
Adamts14 G T 10: 61,225,373 S426Y probably damaging Het
Ankrd24 A G 10: 81,635,161 probably null Het
B3galt5 C A 16: 96,315,723 H185Q probably benign Het
Bod1l A G 5: 41,838,173 probably benign Het
Ddx46 T A 13: 55,666,332 Y700* probably null Het
Dph7 T G 2: 24,971,923 probably null Het
Fcho1 A T 8: 71,713,523 Y354* probably null Het
Fnbp4 A G 2: 90,777,669 M912V probably benign Het
Fpgt T A 3: 155,091,492 E42V possibly damaging Het
Frmd3 A G 4: 74,074,120 I75V possibly damaging Het
Gm10264 G A 12: 88,329,272 G7R unknown Het
Gmds T C 13: 32,127,030 I205V possibly damaging Het
Gprin1 T A 13: 54,740,369 S31C probably damaging Het
Igkv4-68 T C 6: 69,304,881 E102G probably damaging Het
Itga1 T A 13: 114,997,000 Y458F probably benign Het
Kif20b T C 19: 34,938,260 V479A possibly damaging Het
Megf8 T A 7: 25,338,374 W772R probably benign Het
Muc6 T A 7: 141,637,162 I2533F possibly damaging Het
Npas3 T C 12: 54,003,560 S258P probably damaging Het
Padi3 T C 4: 140,796,334 probably benign Het
Pmfbp1 G T 8: 109,537,993 R897L possibly damaging Het
Rims1 A T 1: 22,486,620 W407R probably damaging Het
Scnn1b G T 7: 121,918,036 D632Y probably damaging Het
Tas2r123 G A 6: 132,847,406 A89T probably benign Het
Tbk1 T C 10: 121,551,272 E706G probably benign Het
Thra A G 11: 98,762,928 D195G possibly damaging Het
Tpp2 T A 1: 43,934,187 Y33* probably null Het
Usp6nl T A 2: 6,424,387 M220K probably damaging Het
Vmn2r112 C T 17: 22,618,904 T782I probably damaging Het
Zbtb43 T C 2: 33,453,759 T485A probably benign Het
Zfat T C 15: 68,170,166 I840V possibly damaging Het
Other mutations in Gm3278
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01788:Gm3278 APN 14 4893332 missense probably benign 0.45
R7506:Gm3278 UTSW 14 4893441 missense probably damaging 1.00
R7660:Gm3278 UTSW 14 4893349 missense probably damaging 0.97
R7806:Gm3278 UTSW 14 4895172 critical splice acceptor site probably null
Posted On2013-06-28