Incidental Mutation 'R6925:Ep300'
| ID |
541123 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Ep300
|
| Ensembl Gene |
ENSMUSG00000055024 |
| Gene Name |
E1A binding protein p300 |
| Synonyms |
p300, KAT3B |
| MMRRC Submission |
045043-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R6925 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
15 |
| Chromosomal Location |
81470329-81536278 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
C to A
at 81534182 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Glutamine to Lysine
at position 2080
(Q2080K)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000066789
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000068387]
|
| AlphaFold |
B2RWS6 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000068387
AA Change: Q2080K
PolyPhen 2
Score 0.317 (Sensitivity: 0.90; Specificity: 0.89)
|
| SMART Domains |
Protein: ENSMUSP00000066789
Gene: ENSMUSG00000055024
AA Change: Q2080K
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
18 |
28 |
N/A |
INTRINSIC |
|
low complexity region
|
162 |
178 |
N/A |
INTRINSIC |
|
low complexity region
|
223 |
242 |
N/A |
INTRINSIC |
|
low complexity region
|
296 |
309 |
N/A |
INTRINSIC |
|
ZnF_TAZ
|
333 |
418 |
2.85e-32 |
SMART |
|
low complexity region
|
475 |
488 |
N/A |
INTRINSIC |
|
low complexity region
|
492 |
503 |
N/A |
INTRINSIC |
|
Pfam:KIX
|
567 |
647 |
7.2e-44 |
PFAM |
|
low complexity region
|
722 |
735 |
N/A |
INTRINSIC |
|
low complexity region
|
831 |
848 |
N/A |
INTRINSIC |
|
low complexity region
|
852 |
882 |
N/A |
INTRINSIC |
|
low complexity region
|
884 |
920 |
N/A |
INTRINSIC |
|
low complexity region
|
924 |
943 |
N/A |
INTRINSIC |
|
low complexity region
|
1024 |
1039 |
N/A |
INTRINSIC |
|
BROMO
|
1047 |
1157 |
6.36e-42 |
SMART |
|
Blast:KAT11
|
1227 |
1300 |
9e-22 |
BLAST |
|
KAT11
|
1305 |
1610 |
1.19e-140 |
SMART |
|
ZnF_ZZ
|
1663 |
1704 |
2.67e-15 |
SMART |
|
ZnF_TAZ
|
1728 |
1806 |
5.53e-30 |
SMART |
|
low complexity region
|
1810 |
1836 |
N/A |
INTRINSIC |
|
low complexity region
|
1847 |
1881 |
N/A |
INTRINSIC |
|
low complexity region
|
1902 |
1927 |
N/A |
INTRINSIC |
|
low complexity region
|
1962 |
1979 |
N/A |
INTRINSIC |
|
Pfam:Creb_binding
|
1993 |
2099 |
3.5e-37 |
PFAM |
|
low complexity region
|
2146 |
2158 |
N/A |
INTRINSIC |
|
low complexity region
|
2187 |
2203 |
N/A |
INTRINSIC |
|
low complexity region
|
2205 |
2244 |
N/A |
INTRINSIC |
|
low complexity region
|
2254 |
2265 |
N/A |
INTRINSIC |
|
low complexity region
|
2303 |
2346 |
N/A |
INTRINSIC |
|
low complexity region
|
2390 |
2405 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.4%
- 20x: 98.0%
|
| Validation Efficiency |
100% (91/91) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. It functions as histone acetyltransferase that regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation. It mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein. This gene has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF. Defects in this gene are a cause of Rubinstein-Taybi syndrome and may also play a role in epithelial cancer. [provided by RefSeq, Jul 2008]
PHENOTYPE: Homozygotes for a targeted null mutation exhibit defects of the heart, lung, and small intestine and die at midgestation; heterozygotes also show some embryonic loss. Heterozygotes for an acetyltransferase-negative mutation die by the neonatal period. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 90 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Acat1 |
A |
T |
9: 53,503,329 (GRCm39) |
V170E |
probably benign |
Het |
| Atp2b2 |
T |
A |
6: 113,737,681 (GRCm39) |
I902F |
probably damaging |
Het |
| Cacna1d |
A |
G |
14: 29,773,594 (GRCm39) |
V1697A |
probably benign |
Het |
| Ccdc14 |
T |
A |
16: 34,511,119 (GRCm39) |
F31Y |
probably benign |
Het |
| Ccdc17 |
T |
A |
4: 116,455,407 (GRCm39) |
V250E |
probably damaging |
Het |
| Cct7 |
A |
G |
6: 85,436,164 (GRCm39) |
N25S |
probably damaging |
Het |
| Cdcp3 |
A |
G |
7: 130,824,436 (GRCm39) |
Q177R |
possibly damaging |
Het |
| Cep19 |
G |
C |
16: 31,922,760 (GRCm39) |
G9R |
probably damaging |
Het |
| Ces5a |
A |
T |
8: 94,249,685 (GRCm39) |
|
probably null |
Het |
| Chd1l |
T |
G |
3: 97,490,142 (GRCm39) |
E471A |
probably damaging |
Het |
| Chd6 |
A |
G |
2: 160,855,047 (GRCm39) |
I787T |
probably damaging |
Het |
| Cntnap5c |
A |
C |
17: 58,702,261 (GRCm39) |
T1194P |
probably benign |
Het |
| Col6a3 |
T |
A |
1: 90,743,724 (GRCm39) |
M208L |
probably benign |
Het |
| Coro7 |
A |
T |
16: 4,446,538 (GRCm39) |
|
probably null |
Het |
| Csrnp2 |
T |
C |
15: 100,379,839 (GRCm39) |
K484R |
probably benign |
Het |
| Cyp2c39 |
T |
A |
19: 39,501,639 (GRCm39) |
V64E |
probably damaging |
Het |
| Ddr2 |
T |
C |
1: 169,825,701 (GRCm39) |
K300E |
probably benign |
Het |
| Ddx56 |
T |
C |
11: 6,213,980 (GRCm39) |
E393G |
probably damaging |
Het |
| Diaph1 |
A |
C |
18: 37,986,732 (GRCm39) |
Y1084* |
probably null |
Het |
| Disp1 |
A |
T |
1: 182,868,042 (GRCm39) |
F1459L |
probably benign |
Het |
| Dnajc8 |
G |
A |
4: 132,271,424 (GRCm39) |
A80T |
probably damaging |
Het |
| Elfn1 |
T |
A |
5: 139,957,440 (GRCm39) |
M148K |
probably benign |
Het |
| Emcn |
T |
A |
3: 137,124,763 (GRCm39) |
I154N |
probably damaging |
Het |
| Enah |
T |
A |
1: 181,733,464 (GRCm39) |
|
probably null |
Het |
| Enah |
C |
G |
1: 181,733,463 (GRCm39) |
|
probably null |
Het |
| Epha2 |
T |
A |
4: 141,036,068 (GRCm39) |
M168K |
probably benign |
Het |
| Ercc6 |
T |
A |
14: 32,284,565 (GRCm39) |
I776N |
probably damaging |
Het |
| Fan1 |
T |
A |
7: 64,022,234 (GRCm39) |
N340Y |
probably damaging |
Het |
| Fat4 |
G |
T |
3: 39,050,353 (GRCm39) |
|
probably null |
Het |
| G3bp1 |
A |
G |
11: 55,388,786 (GRCm39) |
R333G |
possibly damaging |
Het |
| Gm3604 |
A |
G |
13: 62,517,204 (GRCm39) |
F385L |
probably benign |
Het |
| Gm5800 |
T |
C |
14: 51,951,157 (GRCm39) |
I147M |
possibly damaging |
Het |
| Hipk1 |
A |
G |
3: 103,685,561 (GRCm39) |
F18S |
unknown |
Het |
| Ighv3-8 |
A |
T |
12: 114,285,950 (GRCm39) |
C131S |
probably benign |
Het |
| Il23r |
T |
G |
6: 67,400,477 (GRCm39) |
T618P |
probably damaging |
Het |
| Il31ra |
G |
A |
13: 112,664,063 (GRCm39) |
T538I |
possibly damaging |
Het |
| Kcns2 |
A |
G |
15: 34,840,059 (GRCm39) |
D474G |
unknown |
Het |
| Klc4 |
T |
C |
17: 46,947,155 (GRCm39) |
T407A |
possibly damaging |
Het |
| Klra5 |
C |
T |
6: 129,888,420 (GRCm39) |
S2N |
probably benign |
Het |
| Krt10 |
T |
C |
11: 99,279,677 (GRCm39) |
Y161C |
probably damaging |
Het |
| Kxd1 |
A |
T |
8: 70,975,928 (GRCm39) |
M1K |
probably null |
Het |
| Lgals1 |
A |
C |
15: 78,812,240 (GRCm39) |
D27A |
possibly damaging |
Het |
| Lgr5 |
T |
C |
10: 115,302,251 (GRCm39) |
S308G |
probably benign |
Het |
| Lrp1 |
G |
A |
10: 127,392,857 (GRCm39) |
S2736L |
probably benign |
Het |
| Lrpap1 |
G |
T |
5: 35,259,880 (GRCm39) |
H73N |
probably benign |
Het |
| Mcpt1 |
C |
A |
14: 56,256,522 (GRCm39) |
T86K |
probably damaging |
Het |
| Megf6 |
A |
T |
4: 154,339,044 (GRCm39) |
D527V |
probably damaging |
Het |
| Mical3 |
A |
T |
6: 120,936,351 (GRCm39) |
S1392T |
probably benign |
Het |
| Mmp2 |
A |
T |
8: 93,566,010 (GRCm39) |
D437V |
probably damaging |
Het |
| Mob4 |
T |
A |
1: 55,191,881 (GRCm39) |
Y166* |
probably null |
Het |
| Mrap2 |
G |
A |
9: 87,064,527 (GRCm39) |
M89I |
possibly damaging |
Het |
| Mug1 |
G |
A |
6: 121,858,746 (GRCm39) |
A1155T |
probably damaging |
Het |
| Myh2 |
G |
T |
11: 67,084,044 (GRCm39) |
A1556S |
probably benign |
Het |
| Nfatc3 |
A |
G |
8: 106,845,954 (GRCm39) |
D1028G |
probably benign |
Het |
| Ngef |
T |
G |
1: 87,430,985 (GRCm39) |
|
probably null |
Het |
| Nlrp1a |
A |
T |
11: 70,983,339 (GRCm39) |
L1209Q |
probably null |
Het |
| Npr2 |
C |
T |
4: 43,647,553 (GRCm39) |
R819C |
probably damaging |
Het |
| Nsd2 |
A |
T |
5: 34,036,454 (GRCm39) |
D646V |
probably damaging |
Het |
| Nsun7 |
A |
G |
5: 66,434,415 (GRCm39) |
H252R |
probably damaging |
Het |
| Or2a25 |
T |
A |
6: 42,888,791 (GRCm39) |
C111* |
probably null |
Het |
| Or2k2 |
A |
T |
4: 58,785,647 (GRCm39) |
I25N |
possibly damaging |
Het |
| Or51a10 |
C |
T |
7: 103,698,947 (GRCm39) |
V205I |
probably benign |
Het |
| Or8g32 |
A |
T |
9: 39,305,156 (GRCm39) |
Q20L |
probably benign |
Het |
| Or8g32 |
G |
T |
9: 39,305,157 (GRCm39) |
Q20H |
probably benign |
Het |
| Pcdhga2 |
A |
T |
18: 37,803,638 (GRCm39) |
D494V |
probably damaging |
Het |
| Pcsk2 |
A |
G |
2: 143,655,667 (GRCm39) |
E617G |
probably damaging |
Het |
| Pdc |
T |
C |
1: 150,208,931 (GRCm39) |
I138T |
probably damaging |
Het |
| Phc2 |
T |
A |
4: 128,641,927 (GRCm39) |
S750T |
probably damaging |
Het |
| Pkd2l1 |
T |
A |
19: 44,179,947 (GRCm39) |
N88Y |
possibly damaging |
Het |
| Plcl1 |
C |
T |
1: 55,445,757 (GRCm39) |
R71* |
probably null |
Het |
| Prag1 |
C |
A |
8: 36,571,048 (GRCm39) |
L544M |
probably damaging |
Het |
| Prkg2 |
A |
G |
5: 99,114,369 (GRCm39) |
|
probably null |
Het |
| Psd2 |
G |
A |
18: 36,112,764 (GRCm39) |
S153N |
probably damaging |
Het |
| Rab11fip1 |
A |
T |
8: 27,643,000 (GRCm39) |
S600T |
probably damaging |
Het |
| Rbms1 |
T |
G |
2: 60,592,648 (GRCm39) |
T222P |
probably benign |
Het |
| Slfn8 |
A |
T |
11: 82,904,243 (GRCm39) |
Y382* |
probably null |
Het |
| Socs4 |
T |
A |
14: 47,527,195 (GRCm39) |
C43* |
probably null |
Het |
| Sorl1 |
T |
A |
9: 41,944,922 (GRCm39) |
T868S |
probably damaging |
Het |
| St6gal1 |
A |
G |
16: 23,174,963 (GRCm39) |
Y267C |
probably damaging |
Het |
| Syne1 |
A |
G |
10: 5,076,682 (GRCm39) |
V6879A |
probably benign |
Het |
| Syne2 |
C |
A |
12: 75,900,906 (GRCm39) |
H22N |
possibly damaging |
Het |
| Tmeff2 |
T |
A |
1: 50,967,180 (GRCm39) |
L25Q |
probably damaging |
Het |
| Tmprss11g |
G |
T |
5: 86,635,285 (GRCm39) |
D396E |
probably benign |
Het |
| Tmprss11g |
T |
A |
5: 86,635,295 (GRCm39) |
H393L |
probably benign |
Het |
| Vmn2r23 |
A |
G |
6: 123,681,512 (GRCm39) |
E140G |
probably damaging |
Het |
| Wapl |
T |
C |
14: 34,399,320 (GRCm39) |
S130P |
probably benign |
Het |
| Zeb2 |
T |
A |
2: 44,884,541 (GRCm39) |
K982M |
probably damaging |
Het |
| Zfhx3 |
C |
G |
8: 109,683,453 (GRCm39) |
H3631D |
unknown |
Het |
| Zfp719 |
T |
C |
7: 43,240,130 (GRCm39) |
S573P |
probably damaging |
Het |
| Zfp979 |
A |
T |
4: 147,697,999 (GRCm39) |
C237S |
possibly damaging |
Het |
|
| Other mutations in Ep300 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00236:Ep300
|
APN |
15 |
81,525,619 (GRCm39) |
missense |
unknown |
|
|
IGL01128:Ep300
|
APN |
15 |
81,514,207 (GRCm39) |
unclassified |
probably benign |
|
|
IGL01151:Ep300
|
APN |
15 |
81,507,673 (GRCm39) |
intron |
probably benign |
|
|
IGL01414:Ep300
|
APN |
15 |
81,511,467 (GRCm39) |
unclassified |
probably benign |
|
|
IGL01564:Ep300
|
APN |
15 |
81,516,665 (GRCm39) |
unclassified |
probably benign |
|
|
IGL01875:Ep300
|
APN |
15 |
81,524,224 (GRCm39) |
missense |
unknown |
|
|
IGL01945:Ep300
|
APN |
15 |
81,500,310 (GRCm39) |
unclassified |
probably benign |
|
|
IGL02022:Ep300
|
APN |
15 |
81,495,638 (GRCm39) |
unclassified |
probably benign |
|
|
IGL02115:Ep300
|
APN |
15 |
81,533,019 (GRCm39) |
missense |
unknown |
|
|
IGL02129:Ep300
|
APN |
15 |
81,470,837 (GRCm39) |
missense |
unknown |
|
|
IGL02145:Ep300
|
APN |
15 |
81,485,367 (GRCm39) |
missense |
unknown |
|
|
IGL02149:Ep300
|
APN |
15 |
81,512,621 (GRCm39) |
unclassified |
probably benign |
|
|
IGL02165:Ep300
|
APN |
15 |
81,525,592 (GRCm39) |
missense |
probably benign |
0.39 |
|
IGL02226:Ep300
|
APN |
15 |
81,497,613 (GRCm39) |
missense |
unknown |
|
|
IGL02610:Ep300
|
APN |
15 |
81,485,723 (GRCm39) |
missense |
unknown |
|
|
IGL02731:Ep300
|
APN |
15 |
81,532,615 (GRCm39) |
missense |
unknown |
|
|
IGL03239:Ep300
|
APN |
15 |
81,525,589 (GRCm39) |
missense |
unknown |
|
|
BB001:Ep300
|
UTSW |
15 |
81,533,703 (GRCm39) |
missense |
unknown |
|
|
BB011:Ep300
|
UTSW |
15 |
81,533,703 (GRCm39) |
missense |
unknown |
|
|
R0077:Ep300
|
UTSW |
15 |
81,525,514 (GRCm39) |
missense |
unknown |
|
|
R0145:Ep300
|
UTSW |
15 |
81,500,328 (GRCm39) |
critical splice donor site |
probably null |
|
|
R0244:Ep300
|
UTSW |
15 |
81,524,329 (GRCm39) |
missense |
unknown |
|
|
R0390:Ep300
|
UTSW |
15 |
81,524,317 (GRCm39) |
missense |
unknown |
|
|
R0534:Ep300
|
UTSW |
15 |
81,485,097 (GRCm39) |
splice site |
probably benign |
|
|
R0671:Ep300
|
UTSW |
15 |
81,500,335 (GRCm39) |
unclassified |
probably benign |
|
|
R0840:Ep300
|
UTSW |
15 |
81,529,134 (GRCm39) |
missense |
unknown |
|
|
R1166:Ep300
|
UTSW |
15 |
81,514,265 (GRCm39) |
unclassified |
probably benign |
|
|
R1737:Ep300
|
UTSW |
15 |
81,510,548 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1893:Ep300
|
UTSW |
15 |
81,515,847 (GRCm39) |
unclassified |
probably benign |
|
|
R2136:Ep300
|
UTSW |
15 |
81,524,648 (GRCm39) |
missense |
unknown |
|
|
R3427:Ep300
|
UTSW |
15 |
81,485,480 (GRCm39) |
missense |
unknown |
|
|
R3757:Ep300
|
UTSW |
15 |
81,532,790 (GRCm39) |
missense |
unknown |
|
|
R3892:Ep300
|
UTSW |
15 |
81,504,198 (GRCm39) |
unclassified |
probably benign |
|
|
R4554:Ep300
|
UTSW |
15 |
81,485,631 (GRCm39) |
missense |
unknown |
|
|
R4575:Ep300
|
UTSW |
15 |
81,495,611 (GRCm39) |
unclassified |
probably benign |
|
|
R4575:Ep300
|
UTSW |
15 |
81,533,210 (GRCm39) |
missense |
unknown |
|
|
R4577:Ep300
|
UTSW |
15 |
81,495,611 (GRCm39) |
unclassified |
probably benign |
|
|
R4577:Ep300
|
UTSW |
15 |
81,533,210 (GRCm39) |
missense |
unknown |
|
|
R4578:Ep300
|
UTSW |
15 |
81,495,611 (GRCm39) |
unclassified |
probably benign |
|
|
R4578:Ep300
|
UTSW |
15 |
81,533,210 (GRCm39) |
missense |
unknown |
|
|
R5021:Ep300
|
UTSW |
15 |
81,524,224 (GRCm39) |
missense |
unknown |
|
|
R5366:Ep300
|
UTSW |
15 |
81,500,301 (GRCm39) |
missense |
probably benign |
0.24 |
|
R5372:Ep300
|
UTSW |
15 |
81,521,031 (GRCm39) |
missense |
unknown |
|
|
R5393:Ep300
|
UTSW |
15 |
81,515,819 (GRCm39) |
unclassified |
probably benign |
|
|
R5410:Ep300
|
UTSW |
15 |
81,533,055 (GRCm39) |
missense |
unknown |
|
|
R5571:Ep300
|
UTSW |
15 |
81,527,418 (GRCm39) |
intron |
probably benign |
|
|
R5701:Ep300
|
UTSW |
15 |
81,485,696 (GRCm39) |
missense |
unknown |
|
|
R5772:Ep300
|
UTSW |
15 |
81,524,115 (GRCm39) |
intron |
probably benign |
|
|
R5825:Ep300
|
UTSW |
15 |
81,495,673 (GRCm39) |
missense |
probably benign |
0.39 |
|
R5917:Ep300
|
UTSW |
15 |
81,512,808 (GRCm39) |
unclassified |
probably benign |
|
|
R5991:Ep300
|
UTSW |
15 |
81,532,667 (GRCm39) |
missense |
unknown |
|
|
R6019:Ep300
|
UTSW |
15 |
81,525,583 (GRCm39) |
missense |
unknown |
|
|
R6144:Ep300
|
UTSW |
15 |
81,485,435 (GRCm39) |
missense |
unknown |
|
|
R6291:Ep300
|
UTSW |
15 |
81,532,708 (GRCm39) |
missense |
unknown |
|
|
R6292:Ep300
|
UTSW |
15 |
81,500,935 (GRCm39) |
unclassified |
probably benign |
|
|
R6599:Ep300
|
UTSW |
15 |
81,470,914 (GRCm39) |
missense |
unknown |
|
|
R6804:Ep300
|
UTSW |
15 |
81,525,512 (GRCm39) |
nonsense |
probably null |
|
|
R7327:Ep300
|
UTSW |
15 |
81,511,515 (GRCm39) |
missense |
unknown |
|
|
R7378:Ep300
|
UTSW |
15 |
81,534,746 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R7388:Ep300
|
UTSW |
15 |
81,532,567 (GRCm39) |
missense |
unknown |
|
|
R7419:Ep300
|
UTSW |
15 |
81,532,715 (GRCm39) |
missense |
unknown |
|
|
R7498:Ep300
|
UTSW |
15 |
81,524,044 (GRCm39) |
missense |
unknown |
|
|
R7584:Ep300
|
UTSW |
15 |
81,512,627 (GRCm39) |
missense |
unknown |
|
|
R7605:Ep300
|
UTSW |
15 |
81,505,353 (GRCm39) |
missense |
unknown |
|
|
R7619:Ep300
|
UTSW |
15 |
81,492,399 (GRCm39) |
missense |
unknown |
|
|
R7699:Ep300
|
UTSW |
15 |
81,470,594 (GRCm39) |
start gained |
probably benign |
|
|
R7763:Ep300
|
UTSW |
15 |
81,470,784 (GRCm39) |
start gained |
probably benign |
|
|
R7775:Ep300
|
UTSW |
15 |
81,470,887 (GRCm39) |
missense |
unknown |
|
|
R7778:Ep300
|
UTSW |
15 |
81,470,887 (GRCm39) |
missense |
unknown |
|
|
R7862:Ep300
|
UTSW |
15 |
81,534,954 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7924:Ep300
|
UTSW |
15 |
81,533,703 (GRCm39) |
missense |
unknown |
|
|
R8155:Ep300
|
UTSW |
15 |
81,505,269 (GRCm39) |
missense |
unknown |
|
|
R8259:Ep300
|
UTSW |
15 |
81,523,218 (GRCm39) |
missense |
unknown |
|
|
R8276:Ep300
|
UTSW |
15 |
81,534,229 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R8331:Ep300
|
UTSW |
15 |
81,485,411 (GRCm39) |
missense |
unknown |
|
|
R8554:Ep300
|
UTSW |
15 |
81,523,228 (GRCm39) |
missense |
unknown |
|
|
R9019:Ep300
|
UTSW |
15 |
81,532,730 (GRCm39) |
missense |
unknown |
|
|
R9128:Ep300
|
UTSW |
15 |
81,533,946 (GRCm39) |
missense |
unknown |
|
|
R9379:Ep300
|
UTSW |
15 |
81,532,760 (GRCm39) |
missense |
unknown |
|
|
R9380:Ep300
|
UTSW |
15 |
81,500,245 (GRCm39) |
missense |
unknown |
|
|
R9484:Ep300
|
UTSW |
15 |
81,521,026 (GRCm39) |
missense |
unknown |
|
|
R9659:Ep300
|
UTSW |
15 |
81,505,273 (GRCm39) |
missense |
unknown |
|
|
R9690:Ep300
|
UTSW |
15 |
81,520,396 (GRCm39) |
missense |
unknown |
|
|
R9721:Ep300
|
UTSW |
15 |
81,492,516 (GRCm39) |
missense |
unknown |
|
|
RF020:Ep300
|
UTSW |
15 |
81,470,772 (GRCm39) |
start gained |
probably benign |
|
|
Z1177:Ep300
|
UTSW |
15 |
81,514,298 (GRCm39) |
frame shift |
probably null |
|
|
| Predicted Primers |
PCR Primer
(F):5'- GGTCAGCCTTTAAACATGGC -3'
(R):5'- ACTCATTGCTCCCATGGGTG -3'
Sequencing Primer
(F):5'- TGGCTCCACAACCAGGATTG -3'
(R):5'- ACCTGCCTGCAGAGGATTCATG -3'
|
| Posted On |
2018-11-28 |
Incidental Mutation