Incidental Mutation 'R6965:Gm10031'
ID541923
Institutional Source Beutler Lab
Gene Symbol Gm10031
Ensembl Gene ENSMUSG00000101523
Gene Namepredicted pseudogene 10031
Synonyms
MMRRC Submission
Accession Numbers
Is this an essential gene? Not available question?
Stock #R6965 (G1)
Quality Score225.009
Status Not validated
Chromosome1
Chromosomal Location156524012-156526664 bp(+) (GRCm38)
Type of Mutationnonsense
DNA Base Change (assembly) C to T at 156524549 bp
ZygosityHeterozygous
Amino Acid Change Arginine to Stop codon at position 107 (R107*)
Ref Sequence ENSEMBL: ENSMUSP00000140515 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000190422]
Predicted Effect probably null
Transcript: ENSMUST00000190422
AA Change: R107*
SMART Domains Protein: ENSMUSP00000140515
Gene: ENSMUSG00000101523
AA Change: R107*

DomainStartEndE-ValueType
S_TKc 39 324 1.88e-78 SMART
Coding Region Coverage
  • 1x: 100.0%
  • 3x: 99.9%
  • 10x: 99.3%
  • 20x: 97.3%
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 59 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Abca14 C T 7: 120,283,229 Q1205* probably null Het
Als2 A G 1: 59,170,557 F1422S possibly damaging Het
Anapc4 T C 5: 52,835,751 V68A possibly damaging Het
Atmin T C 8: 116,957,038 F479S probably damaging Het
Atp7b T C 8: 22,028,085 T234A probably benign Het
Bpifa1 G A 2: 154,145,661 G144S probably damaging Het
Brf2 A T 8: 27,124,558 M200K probably benign Het
C1ql2 G A 1: 120,341,215 C33Y probably damaging Het
Cdk18 A G 1: 132,117,581 V269A probably damaging Het
Clcc1 T C 3: 108,673,309 V313A probably damaging Het
Cntrl A T 2: 35,162,833 T1117S probably benign Het
Col15a1 G A 4: 47,247,533 E236K probably damaging Het
Comp T C 8: 70,376,514 L278P probably damaging Het
Dlg5 C A 14: 24,149,430 D1469Y probably damaging Het
Efna1 A T 3: 89,279,475 V23D probably damaging Het
Enpp5 G A 17: 44,085,264 G356S probably damaging Het
Epb41l4b T C 4: 57,040,915 Y516C probably damaging Het
Esr2 T C 12: 76,121,857 D526G probably damaging Het
Fam184b T C 5: 45,555,135 T514A probably benign Het
Fcmr A C 1: 130,875,987 E176A possibly damaging Het
Fry T A 5: 150,416,220 N1485K possibly damaging Het
Fut2 A G 7: 45,650,881 C156R probably damaging Het
Gm5431 T C 11: 48,895,200 Y116C probably benign Het
Gm5493 T A 17: 22,748,074 V61E possibly damaging Het
Golga4 A T 9: 118,548,779 Q456L probably damaging Het
Gpam T C 19: 55,074,609 Y757C probably damaging Het
Iqcg C T 16: 33,030,804 A266T probably benign Het
Lta4h G T 10: 93,471,897 G331* probably null Het
Macf1 C A 4: 123,408,745 V655F probably benign Het
Map3k13 T A 16: 21,922,150 D742E probably benign Het
Mrgprb2 G A 7: 48,552,849 L43F probably damaging Het
N4bp1 T C 8: 86,844,833 R846G probably damaging Het
Nbn T C 4: 15,970,863 I282T probably benign Het
Ncor1 C T 11: 62,353,233 probably null Het
Olfr1250 G T 2: 89,656,665 P259T probably damaging Het
Olfr1426 A G 19: 12,088,756 F12S possibly damaging Het
Olfr874 T A 9: 37,746,137 M1K probably null Het
Pclo A G 5: 14,681,962 probably benign Het
Pde9a G T 17: 31,443,887 V97L probably benign Het
Ptch1 T C 13: 63,525,067 Y771C possibly damaging Het
R3hcc1l G A 19: 42,562,845 D94N probably damaging Het
Rnpep T A 1: 135,263,120 K602* probably null Het
Rph3al T C 11: 75,854,450 Y156C probably damaging Het
Rundc1 A T 11: 101,433,911 Y481F possibly damaging Het
Serpinb9f A G 13: 33,325,876 K17R possibly damaging Het
Smpd3 T C 8: 106,259,881 H459R probably damaging Het
Spata31 A C 13: 64,922,834 Q932P possibly damaging Het
Srgap3 C T 6: 112,723,129 A963T probably damaging Het
Syne1 A T 10: 5,229,120 F4451L possibly damaging Het
Tbc1d19 T A 5: 53,856,924 probably null Het
Thap12 T A 7: 98,715,462 V279D probably damaging Het
Tmprss6 T C 15: 78,444,128 D544G probably damaging Het
Tox2 A G 2: 163,323,010 *523W probably null Het
Txnrd1 T C 10: 82,881,818 I212T probably benign Het
Unc80 T C 1: 66,646,566 I2283T probably benign Het
Vmn1r176 A G 7: 23,835,674 I18T possibly damaging Het
Vmn2r101 C T 17: 19,591,022 T456I probably benign Het
Vmn2r79 T A 7: 87,001,892 H166Q probably benign Het
Zer1 A G 2: 30,101,047 V723A possibly damaging Het
Other mutations in Gm10031
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL03394:Gm10031 APN 1 156525222 missense probably benign 0.34
R5578:Gm10031 UTSW 1 156525230 missense probably benign
R6058:Gm10031 UTSW 1 156524855 missense probably damaging 1.00
R6249:Gm10031 UTSW 1 156525230 missense probably benign
R7514:Gm10031 UTSW 1 156524754 missense probably benign 0.05
R7761:Gm10031 UTSW 1 156525137 nonsense probably null
R7765:Gm10031 UTSW 1 156524784 missense possibly damaging 0.47
R7782:Gm10031 UTSW 1 156524982 missense probably damaging 1.00
R7889:Gm10031 UTSW 1 156525395 missense probably benign
R7972:Gm10031 UTSW 1 156525395 missense probably benign
Predicted Primers PCR Primer
(F):5'- ACCAGCTTGTTCGAAAATTAGG -3'
(R):5'- CGAAGCTTTCTGTGCTCATG -3'

Sequencing Primer
(F):5'- CCAGCTTGTTCGAAAATTAGGTAGGG -3'
(R):5'- GAAGCTTTCTGTGCTCATGATCAATC -3'
Posted On2018-11-28