Mutagenetix > Incidental Mutation

Incidental Mutation 'R6975:Igfn1'

542397

Institutional Source

Beutler Lab

Gene Symbol

Igfn1

Ensembl Gene

ENSMUSG00000051985

Gene Name

immunoglobulin-like and fibronectin type III domain containing 1

Synonyms

9830123M21Rik

MMRRC Submission

045085-MU

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.099) question?

Stock #

R6975 (G1)

Quality Score

225.009

Status

Validated

Chromosome

Chromosomal Location

135881316-135934080 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

T to A at 135896183 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Asparagine to Isoleucine at position 1461 (N1461I)

Ref Sequence

ENSEMBL: ENSMUSP00000129680 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000166193]

AlphaFold

no structure available at present

Predicted Effect

probably benign
Transcript: ENSMUST00000124134

SMART Domains

Protein: ENSMUSP00000119230
Gene: ENSMUSG00000051985

Domain	Start	End	E-Value	Type
IG	73	159	1.29e-6	SMART
IG_like	258	344	5.45e1	SMART
IG	354	435	1.79e0	SMART
IG	445	524	3.54e-4	SMART
IG	538	624	4.86e-2	SMART
FN3	627	711	3.99e-10	SMART
FN3	727	810	9.1e-14	SMART
FN3	828	911	1.5e-14	SMART
IG	938	1021	6.41e-2	SMART
FN3	1024	1106	3.2e-9	SMART
IGc2	1152	1219	4.89e-7	SMART

Predicted Effect

probably damaging
Transcript: ENSMUST00000166193
AA Change: N1461I

PolyPhen 2 Score 0.964 (Sensitivity: 0.78; Specificity: 0.95)

SMART Domains

Protein: ENSMUSP00000129680
Gene: ENSMUSG00000051985
AA Change: N1461I

Domain	Start	End	E-Value	Type
low complexity region	90	101	N/A	INTRINSIC
IG	193	279	1.29e-6	SMART
PDB:2LHU\|A	302	365	8e-7	PDB
IG_like	378	464	5.45e1	SMART
IG	474	555	1.79e0	SMART
low complexity region	724	739	N/A	INTRINSIC
internal_repeat_2	838	1006	9.98e-5	PROSPERO
low complexity region	1067	1084	N/A	INTRINSIC
internal_repeat_2	1812	1967	9.98e-5	PROSPERO
Pfam:I-set	2054	2139	6.2e-8	PFAM
IG	2153	2239	4.86e-2	SMART
FN3	2242	2326	3.99e-10	SMART
FN3	2342	2425	9.1e-14	SMART
FN3	2443	2526	1.5e-14	SMART
IG	2553	2636	6.41e-2	SMART
FN3	2639	2721	3.2e-9	SMART
IGc2	2767	2834	4.89e-7	SMART

Coding Region Coverage

1x: 100.0%
3x: 99.9%
10x: 99.2%
20x: 96.9%

Validation Efficiency

100% (46/46)

Allele List at MGI

Other mutations in this stock

Total: 46 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
2010315B03Rik	T	A	9: 124,056,687 (GRCm39)	H100L	probably benign	Het
Apaf1	A	T	10: 90,856,596 (GRCm39)	H870Q	probably damaging	Het
Aplf	T	C	6: 87,623,068 (GRCm39)	D358G	probably damaging	Het
Atp10a	A	T	7: 58,423,733 (GRCm39)	S233C	probably damaging	Het
Ccdc158	A	T	5: 92,814,579 (GRCm39)	Y82*	probably null	Het
Clba1	C	T	12: 112,773,217 (GRCm39)	P70L	possibly damaging	Het
Cubn	T	C	2: 13,491,600 (GRCm39)	D149G	probably damaging	Het
Cyp4f14	T	C	17: 33,133,608 (GRCm39)	T83A	probably benign	Het
Endog	A	G	2: 30,061,648 (GRCm39)		probably benign	Het
Extl3	T	C	14: 65,304,246 (GRCm39)	E721G	probably benign	Het
Gatad1	T	C	5: 3,693,540 (GRCm39)	R210G	probably benign	Het
Gcn1	A	G	5: 115,751,518 (GRCm39)	H2033R	probably damaging	Het
Gm12830	T	C	4: 114,702,246 (GRCm39)	M136T		Het
Gm6871	T	C	7: 41,196,202 (GRCm39)		silent	Het
Hoxc4	T	C	15: 102,944,098 (GRCm39)	S159P	probably damaging	Het
Ift70a2	T	C	2: 75,806,752 (GRCm39)	R587G	probably damaging	Het
Ift70a2	A	T	2: 75,808,004 (GRCm39)	Y169*	probably null	Het
Igf2bp2	T	A	16: 21,880,611 (GRCm39)	Q494L	probably null	Het
Il23r	C	A	6: 67,400,352 (GRCm39)	K659N	probably damaging	Het
Map3k11	A	G	19: 5,740,755 (GRCm39)	S161G	possibly damaging	Het
Naip6	T	A	13: 100,452,773 (GRCm39)	Q96L	probably damaging	Het
Nup133	T	C	8: 124,642,057 (GRCm39)	E802G	probably damaging	Het
Nutm1	G	A	2: 112,086,563 (GRCm39)	S56F	probably damaging	Het
Or10x4	T	A	1: 174,219,243 (GRCm39)	S203T	probably benign	Het
Or51a24	T	C	7: 103,734,002 (GRCm39)	N95S	probably benign	Het
Otop2	A	T	11: 115,220,152 (GRCm39)	S331C	possibly damaging	Het
Pira1	C	G	7: 3,740,319 (GRCm39)	A301P	probably damaging	Het
Pkd1l3	A	G	8: 110,387,539 (GRCm39)	R1818G	possibly damaging	Het
Pms1	A	T	1: 53,228,590 (GRCm39)	I886N	probably damaging	Het
Pnpla6	A	G	8: 3,588,068 (GRCm39)	Y1107C	probably damaging	Het
Ppp3ca	A	G	3: 136,611,062 (GRCm39)	T362A	probably damaging	Het
Rarb	A	G	14: 16,574,942 (GRCm38)	S25P	possibly damaging	Het
Rnf121	A	T	7: 101,673,218 (GRCm39)		probably null	Het
Sae1	T	C	7: 16,070,712 (GRCm39)	Y266C	probably damaging	Het
Scpep1	A	T	11: 88,838,031 (GRCm39)	F85L	probably damaging	Het
Shank1	T	A	7: 43,962,530 (GRCm39)		probably null	Het
Slc40a1	T	C	1: 45,948,652 (GRCm39)	K543E	probably benign	Het
Slc9a9	A	G	9: 94,842,499 (GRCm39)	Y350C	probably damaging	Het
Sun2	G	T	15: 79,618,420 (GRCm39)	Y246*	probably null	Het
Tas1r2	T	A	4: 139,397,031 (GRCm39)	I790N	probably damaging	Het
Tmtc2	T	C	10: 105,158,863 (GRCm39)	T577A	probably benign	Het
Trim24	T	G	6: 37,896,427 (GRCm39)		probably null	Het
Ttc12	A	G	9: 49,349,718 (GRCm39)	V693A	probably benign	Het
Zbtb22	A	C	17: 34,136,938 (GRCm39)	D361A	probably damaging	Het
Zfp276	T	A	8: 123,983,570 (GRCm39)	C324*	probably null	Het
Zfp536	A	G	7: 37,267,952 (GRCm39)	L488P	probably damaging	Het

Other mutations in Igfn1

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00753:Igfn1	APN	1	135,894,464 (GRCm39)	missense	probably damaging	1.00
IGL02299:Igfn1	APN	1	135,881,755 (GRCm39)	utr 3 prime	probably benign
Bounty	UTSW	1	135,904,655 (GRCm39)	critical splice donor site	probably null
R2276_Igfn1_773	UTSW	1	135,892,479 (GRCm39)	missense	probably damaging	0.98
R4058_Igfn1_315	UTSW	1	135,897,494 (GRCm39)	missense	probably benign	0.07
R0144:Igfn1	UTSW	1	135,889,751 (GRCm39)	missense	probably damaging	0.99
R0190:Igfn1	UTSW	1	135,889,790 (GRCm39)	missense	probably damaging	1.00
R0350:Igfn1	UTSW	1	135,884,505 (GRCm39)	nonsense	probably null
R0413:Igfn1	UTSW	1	135,895,334 (GRCm39)	missense	probably benign	0.23
R0504:Igfn1	UTSW	1	135,896,267 (GRCm39)	missense	probably benign	0.00
R0606:Igfn1	UTSW	1	135,887,639 (GRCm39)	missense	probably damaging	1.00
R0681:Igfn1	UTSW	1	135,891,591 (GRCm39)	missense	possibly damaging	0.88
R0825:Igfn1	UTSW	1	135,890,864 (GRCm39)	missense	probably damaging	1.00
R0839:Igfn1	UTSW	1	135,882,418 (GRCm39)	missense	probably damaging	1.00
R1066:Igfn1	UTSW	1	135,898,463 (GRCm39)	missense	probably benign
R1078:Igfn1	UTSW	1	135,902,585 (GRCm39)	missense	probably damaging	1.00
R1224:Igfn1	UTSW	1	135,897,494 (GRCm39)	missense	probably benign	0.07
R1569:Igfn1	UTSW	1	135,896,771 (GRCm39)	missense	probably benign
R1626:Igfn1	UTSW	1	135,896,705 (GRCm39)	missense	probably benign	0.29
R1663:Igfn1	UTSW	1	135,896,046 (GRCm39)	missense	probably benign	0.15
R1677:Igfn1	UTSW	1	135,898,839 (GRCm39)	missense	probably damaging	0.99
R1709:Igfn1	UTSW	1	135,883,311 (GRCm39)	missense	probably benign	0.24
R1728:Igfn1	UTSW	1	135,926,421 (GRCm39)	missense	unknown
R1728:Igfn1	UTSW	1	135,926,363 (GRCm39)	missense	probably benign
R1728:Igfn1	UTSW	1	135,910,213 (GRCm39)	missense	probably benign
R1728:Igfn1	UTSW	1	135,907,653 (GRCm39)	missense	probably benign	0.00
R1728:Igfn1	UTSW	1	135,899,865 (GRCm39)	missense	probably benign
R1728:Igfn1	UTSW	1	135,898,149 (GRCm39)	missense	probably benign
R1728:Igfn1	UTSW	1	135,895,937 (GRCm39)	missense	probably benign
R1728:Igfn1	UTSW	1	135,887,666 (GRCm39)	missense	probably damaging	1.00
R1729:Igfn1	UTSW	1	135,910,213 (GRCm39)	missense	probably benign
R1729:Igfn1	UTSW	1	135,907,653 (GRCm39)	missense	probably benign	0.00
R1729:Igfn1	UTSW	1	135,899,865 (GRCm39)	missense	probably benign
R1729:Igfn1	UTSW	1	135,898,149 (GRCm39)	missense	probably benign
R1729:Igfn1	UTSW	1	135,895,937 (GRCm39)	missense	probably benign
R1729:Igfn1	UTSW	1	135,887,666 (GRCm39)	missense	probably damaging	1.00
R1729:Igfn1	UTSW	1	135,926,421 (GRCm39)	missense	unknown
R1729:Igfn1	UTSW	1	135,926,363 (GRCm39)	missense	probably benign
R1730:Igfn1	UTSW	1	135,887,666 (GRCm39)	missense	probably damaging	1.00
R1730:Igfn1	UTSW	1	135,895,937 (GRCm39)	missense	probably benign
R1730:Igfn1	UTSW	1	135,898,149 (GRCm39)	missense	probably benign
R1730:Igfn1	UTSW	1	135,899,865 (GRCm39)	missense	probably benign
R1730:Igfn1	UTSW	1	135,907,653 (GRCm39)	missense	probably benign	0.00
R1730:Igfn1	UTSW	1	135,910,213 (GRCm39)	missense	probably benign
R1730:Igfn1	UTSW	1	135,926,363 (GRCm39)	missense	probably benign
R1730:Igfn1	UTSW	1	135,926,421 (GRCm39)	missense	unknown
R1739:Igfn1	UTSW	1	135,899,865 (GRCm39)	missense	probably benign
R1739:Igfn1	UTSW	1	135,907,653 (GRCm39)	missense	probably benign	0.00
R1739:Igfn1	UTSW	1	135,910,213 (GRCm39)	missense	probably benign
R1739:Igfn1	UTSW	1	135,926,363 (GRCm39)	missense	probably benign
R1739:Igfn1	UTSW	1	135,898,149 (GRCm39)	missense	probably benign
R1739:Igfn1	UTSW	1	135,895,937 (GRCm39)	missense	probably benign
R1739:Igfn1	UTSW	1	135,887,666 (GRCm39)	missense	probably damaging	1.00
R1739:Igfn1	UTSW	1	135,926,421 (GRCm39)	missense	unknown
R1746:Igfn1	UTSW	1	135,897,561 (GRCm39)	missense	possibly damaging	0.88
R1762:Igfn1	UTSW	1	135,926,363 (GRCm39)	missense	probably benign
R1762:Igfn1	UTSW	1	135,910,213 (GRCm39)	missense	probably benign
R1762:Igfn1	UTSW	1	135,907,653 (GRCm39)	missense	probably benign	0.00
R1762:Igfn1	UTSW	1	135,899,865 (GRCm39)	missense	probably benign
R1762:Igfn1	UTSW	1	135,898,149 (GRCm39)	missense	probably benign
R1762:Igfn1	UTSW	1	135,895,937 (GRCm39)	missense	probably benign
R1762:Igfn1	UTSW	1	135,887,666 (GRCm39)	missense	probably damaging	1.00
R1762:Igfn1	UTSW	1	135,926,421 (GRCm39)	missense	unknown
R1783:Igfn1	UTSW	1	135,910,213 (GRCm39)	missense	probably benign
R1783:Igfn1	UTSW	1	135,907,653 (GRCm39)	missense	probably benign	0.00
R1783:Igfn1	UTSW	1	135,899,865 (GRCm39)	missense	probably benign
R1783:Igfn1	UTSW	1	135,898,149 (GRCm39)	missense	probably benign
R1783:Igfn1	UTSW	1	135,895,937 (GRCm39)	missense	probably benign
R1783:Igfn1	UTSW	1	135,887,666 (GRCm39)	missense	probably damaging	1.00
R1783:Igfn1	UTSW	1	135,926,421 (GRCm39)	missense	unknown
R1783:Igfn1	UTSW	1	135,926,363 (GRCm39)	missense	probably benign
R1784:Igfn1	UTSW	1	135,926,421 (GRCm39)	missense	unknown
R1784:Igfn1	UTSW	1	135,926,363 (GRCm39)	missense	probably benign
R1784:Igfn1	UTSW	1	135,910,213 (GRCm39)	missense	probably benign
R1784:Igfn1	UTSW	1	135,907,653 (GRCm39)	missense	probably benign	0.00
R1784:Igfn1	UTSW	1	135,899,865 (GRCm39)	missense	probably benign
R1784:Igfn1	UTSW	1	135,898,149 (GRCm39)	missense	probably benign
R1784:Igfn1	UTSW	1	135,895,937 (GRCm39)	missense	probably benign
R1784:Igfn1	UTSW	1	135,887,666 (GRCm39)	missense	probably damaging	1.00
R1785:Igfn1	UTSW	1	135,926,421 (GRCm39)	missense	unknown
R1785:Igfn1	UTSW	1	135,926,363 (GRCm39)	missense	probably benign
R1785:Igfn1	UTSW	1	135,910,213 (GRCm39)	missense	probably benign
R1785:Igfn1	UTSW	1	135,907,653 (GRCm39)	missense	probably benign	0.00
R1785:Igfn1	UTSW	1	135,899,865 (GRCm39)	missense	probably benign
R1785:Igfn1	UTSW	1	135,898,149 (GRCm39)	missense	probably benign
R1785:Igfn1	UTSW	1	135,895,937 (GRCm39)	missense	probably benign
R1785:Igfn1	UTSW	1	135,887,666 (GRCm39)	missense	probably damaging	1.00
R1847:Igfn1	UTSW	1	135,897,126 (GRCm39)	missense	probably benign
R1866:Igfn1	UTSW	1	135,902,606 (GRCm39)	splice site	probably null
R1921:Igfn1	UTSW	1	135,893,801 (GRCm39)	critical splice donor site	probably null
R1984:Igfn1	UTSW	1	135,889,782 (GRCm39)	missense	probably benign	0.39
R2049:Igfn1	UTSW	1	135,902,590 (GRCm39)	splice site	probably benign
R2049:Igfn1	UTSW	1	135,898,376 (GRCm39)	missense	probably benign
R2098:Igfn1	UTSW	1	135,906,043 (GRCm39)	missense	probably damaging	1.00
R2130:Igfn1	UTSW	1	135,902,590 (GRCm39)	splice site	probably benign
R2141:Igfn1	UTSW	1	135,902,590 (GRCm39)	splice site	probably benign
R2276:Igfn1	UTSW	1	135,892,479 (GRCm39)	missense	probably damaging	0.98
R2425:Igfn1	UTSW	1	135,890,840 (GRCm39)	missense	probably damaging	1.00
R2483:Igfn1	UTSW	1	135,897,275 (GRCm39)	missense	probably benign
R2504:Igfn1	UTSW	1	135,897,054 (GRCm39)	missense	probably benign	0.07
R3109:Igfn1	UTSW	1	135,925,586 (GRCm39)	missense	probably benign	0.12
R3421:Igfn1	UTSW	1	135,904,655 (GRCm39)	critical splice donor site	probably null
R3423:Igfn1	UTSW	1	135,926,379 (GRCm39)	missense	probably benign	0.01
R3705:Igfn1	UTSW	1	135,896,147 (GRCm39)	missense	probably benign
R3871:Igfn1	UTSW	1	135,896,574 (GRCm39)	missense	probably benign	0.03
R3875:Igfn1	UTSW	1	135,882,352 (GRCm39)	missense	probably damaging	1.00
R3953:Igfn1	UTSW	1	135,894,918 (GRCm39)	missense	possibly damaging	0.61
R3955:Igfn1	UTSW	1	135,894,918 (GRCm39)	missense	possibly damaging	0.61
R3957:Igfn1	UTSW	1	135,894,918 (GRCm39)	missense	possibly damaging	0.61
R3965:Igfn1	UTSW	1	135,895,557 (GRCm39)	missense	probably benign
R4006:Igfn1	UTSW	1	135,910,100 (GRCm39)	splice site	probably null
R4058:Igfn1	UTSW	1	135,897,494 (GRCm39)	missense	probably benign	0.07
R4059:Igfn1	UTSW	1	135,897,494 (GRCm39)	missense	probably benign	0.07
R4370:Igfn1	UTSW	1	135,895,844 (GRCm39)	missense	probably benign	0.00
R4380:Igfn1	UTSW	1	135,895,509 (GRCm39)	missense	probably benign	0.00
R4495:Igfn1	UTSW	1	135,897,416 (GRCm39)	missense	possibly damaging	0.79
R4628:Igfn1	UTSW	1	135,887,468 (GRCm39)	missense	possibly damaging	0.47
R4672:Igfn1	UTSW	1	135,893,107 (GRCm39)	missense	possibly damaging	0.72
R4682:Igfn1	UTSW	1	135,926,363 (GRCm39)	missense	probably benign
R4702:Igfn1	UTSW	1	135,894,947 (GRCm39)	missense	possibly damaging	0.71
R4744:Igfn1	UTSW	1	135,910,196 (GRCm39)	missense	probably benign	0.07
R4777:Igfn1	UTSW	1	135,882,600 (GRCm39)	missense	probably benign
R4806:Igfn1	UTSW	1	135,895,095 (GRCm39)	missense	probably benign	0.01
R4840:Igfn1	UTSW	1	135,895,778 (GRCm39)	missense	probably benign	0.00
R4894:Igfn1	UTSW	1	135,882,520 (GRCm39)	missense	probably damaging	1.00
R4998:Igfn1	UTSW	1	135,882,404 (GRCm39)	missense	probably damaging	1.00
R5092:Igfn1	UTSW	1	135,892,564 (GRCm39)	missense	probably benign
R5108:Igfn1	UTSW	1	135,910,179 (GRCm39)	missense	probably benign
R5120:Igfn1	UTSW	1	135,901,240 (GRCm39)	missense	possibly damaging	0.93
R5127:Igfn1	UTSW	1	135,887,634 (GRCm39)	missense	probably damaging	1.00
R5231:Igfn1	UTSW	1	135,894,474 (GRCm39)	missense	probably benign	0.26
R5286:Igfn1	UTSW	1	135,895,599 (GRCm39)	missense	probably benign	0.10
R5307:Igfn1	UTSW	1	135,892,676 (GRCm39)	missense	probably damaging	1.00
R5380:Igfn1	UTSW	1	135,893,825 (GRCm39)	missense	probably damaging	1.00
R5553:Igfn1	UTSW	1	135,895,622 (GRCm39)	missense	probably damaging	1.00
R5660:Igfn1	UTSW	1	135,898,152 (GRCm39)	missense	probably benign	0.01
R5779:Igfn1	UTSW	1	135,894,578 (GRCm39)	missense	probably benign	0.16
R5818:Igfn1	UTSW	1	135,893,864 (GRCm39)	missense	possibly damaging	0.72
R5832:Igfn1	UTSW	1	135,902,533 (GRCm39)	missense	probably damaging	0.96
R5933:Igfn1	UTSW	1	135,898,341 (GRCm39)	nonsense	probably null
R5966:Igfn1	UTSW	1	135,893,152 (GRCm39)	missense	probably damaging	1.00
R6116:Igfn1	UTSW	1	135,898,205 (GRCm39)	missense	probably benign	0.00
R6297:Igfn1	UTSW	1	135,892,399 (GRCm39)	critical splice donor site	probably null
R6652:Igfn1	UTSW	1	135,891,609 (GRCm39)	missense	probably damaging	1.00
R6737:Igfn1	UTSW	1	135,897,605 (GRCm39)	missense	probably benign
R6816:Igfn1	UTSW	1	135,887,466 (GRCm39)	missense	probably benign	0.02
R6886:Igfn1	UTSW	1	135,901,198 (GRCm39)	missense	probably damaging	1.00
R6888:Igfn1	UTSW	1	135,910,218 (GRCm39)	missense	probably benign	0.33
R7105:Igfn1	UTSW	1	135,911,956 (GRCm39)	missense	probably benign	0.11
R7114:Igfn1	UTSW	1	135,894,519 (GRCm39)	missense	probably benign	0.01
R7233:Igfn1	UTSW	1	135,897,873 (GRCm39)	missense	probably benign	0.41
R7276:Igfn1	UTSW	1	135,926,376 (GRCm39)	missense	possibly damaging	0.85
R7354:Igfn1	UTSW	1	135,903,770 (GRCm39)	missense	possibly damaging	0.72
R7358:Igfn1	UTSW	1	135,891,738 (GRCm39)	missense	probably damaging	1.00
R7380:Igfn1	UTSW	1	135,889,746 (GRCm39)	missense	probably damaging	1.00
R7389:Igfn1	UTSW	1	135,894,785 (GRCm39)	missense	probably benign	0.00
R7513:Igfn1	UTSW	1	135,887,705 (GRCm39)	missense	probably damaging	1.00
R7718:Igfn1	UTSW	1	135,896,774 (GRCm39)	missense	probably benign
R7769:Igfn1	UTSW	1	135,910,143 (GRCm39)	missense	possibly damaging	0.85
R7810:Igfn1	UTSW	1	135,902,527 (GRCm39)	missense	probably damaging	0.98
R7917:Igfn1	UTSW	1	135,899,706 (GRCm39)	missense	probably damaging	0.99
R7952:Igfn1	UTSW	1	135,891,693 (GRCm39)	missense	probably damaging	0.99
R8041:Igfn1	UTSW	1	135,895,797 (GRCm39)	nonsense	probably null
R8233:Igfn1	UTSW	1	135,895,782 (GRCm39)	missense	probably benign	0.00
R8354:Igfn1	UTSW	1	135,887,619 (GRCm39)	missense	possibly damaging	0.61
R8363:Igfn1	UTSW	1	135,891,625 (GRCm39)	missense	probably benign	0.01
R8428:Igfn1	UTSW	1	135,895,520 (GRCm39)	missense	probably damaging	1.00
R8731:Igfn1	UTSW	1	135,925,574 (GRCm39)	missense	probably benign	0.02
R8756:Igfn1	UTSW	1	135,895,698 (GRCm39)	missense	probably benign	0.10
R8797:Igfn1	UTSW	1	135,902,573 (GRCm39)	missense	possibly damaging	0.93
R8913:Igfn1	UTSW	1	135,891,579 (GRCm39)	missense	possibly damaging	0.90
R8927:Igfn1	UTSW	1	135,905,984 (GRCm39)	missense	probably damaging	1.00
R8928:Igfn1	UTSW	1	135,905,984 (GRCm39)	missense	probably damaging	1.00
R9087:Igfn1	UTSW	1	135,902,606 (GRCm39)	splice site	probably null
R9109:Igfn1	UTSW	1	135,926,327 (GRCm39)	missense	probably benign	0.26
R9113:Igfn1	UTSW	1	135,883,328 (GRCm39)	missense	probably damaging	1.00
R9117:Igfn1	UTSW	1	135,902,528 (GRCm39)	missense	probably benign	0.03
R9205:Igfn1	UTSW	1	135,903,695 (GRCm39)	missense	probably damaging	0.96
R9251:Igfn1	UTSW	1	135,894,409 (GRCm39)	splice site	probably benign
R9260:Igfn1	UTSW	1	135,907,694 (GRCm39)	missense	probably benign	0.45
R9275:Igfn1	UTSW	1	135,901,185 (GRCm39)	missense	probably damaging	0.96
R9277:Igfn1	UTSW	1	135,887,520 (GRCm39)	missense	probably damaging	0.98
R9278:Igfn1	UTSW	1	135,901,185 (GRCm39)	missense	probably damaging	0.96
R9287:Igfn1	UTSW	1	135,925,544 (GRCm39)	missense	probably benign	0.33
R9298:Igfn1	UTSW	1	135,926,327 (GRCm39)	missense	probably benign	0.26
R9356:Igfn1	UTSW	1	135,899,825 (GRCm39)	nonsense	probably null
R9371:Igfn1	UTSW	1	135,906,001 (GRCm39)	missense	probably damaging	1.00
R9532:Igfn1	UTSW	1	135,897,229 (GRCm39)	missense	possibly damaging	0.61
R9653:Igfn1	UTSW	1	135,883,323 (GRCm39)	nonsense	probably null
R9666:Igfn1	UTSW	1	135,897,692 (GRCm39)	missense	possibly damaging	0.65
R9741:Igfn1	UTSW	1	135,895,383 (GRCm39)	missense	probably benign	0.00
R9748:Igfn1	UTSW	1	135,926,336 (GRCm39)	missense	possibly damaging	0.89
R9796:Igfn1	UTSW	1	135,897,611 (GRCm39)	missense	probably benign	0.26
Z1176:Igfn1	UTSW	1	135,899,738 (GRCm39)	missense	probably damaging	0.99
Z1177:Igfn1	UTSW	1	135,910,164 (GRCm39)	missense	possibly damaging	0.73
Z1177:Igfn1	UTSW	1	135,897,305 (GRCm39)	missense	probably benign	0.26
Z1177:Igfn1	UTSW	1	135,883,547 (GRCm39)	missense	probably damaging	1.00

Predicted Primers

PCR Primer
(F):5'- GCAAGGTGCATTTTCCTCTC -3'
(R):5'- CTTCGAGCCTCAGAGGAATG -3'

Sequencing Primer
(F):5'- TGACCCCATTTCCCCAGGAC -3'
(R):5'- CCTCAGAGGAATGGGACCAGC -3'

Posted On

2018-11-28