Mutagenetix > Incidental Mutation

Incidental Mutation 'R0607:Dnhd1'

54273

Institutional Source

Beutler Lab

Gene Symbol

Dnhd1

Ensembl Gene

ENSMUSG00000030882

Gene Name

dynein heavy chain domain 1

Synonyms

8030491N06Rik

MMRRC Submission

038796-MU

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.090) question?

Stock #

R0607 (G1)

Quality Score

225

Status

Not validated

Chromosome

Chromosomal Location

105300034-105371006 bp(+) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

T to A at 105369995 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Asparagine to Lysine at position 4473 (N4473K)

Ref Sequence

ENSEMBL: ENSMUSP00000121261 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000145988]

AlphaFold

no structure available at present

Predicted Effect

probably benign
Transcript: ENSMUST00000145988
AA Change: N4473K

PolyPhen 2 Score 0.039 (Sensitivity: 0.94; Specificity: 0.83)

SMART Domains

Protein: ENSMUSP00000121261
Gene: ENSMUSG00000030882
AA Change: N4473K

Domain	Start	End	E-Value	Type
low complexity region	5	18	N/A	INTRINSIC
low complexity region	102	115	N/A	INTRINSIC
low complexity region	183	191	N/A	INTRINSIC
low complexity region	253	269	N/A	INTRINSIC
low complexity region	943	962	N/A	INTRINSIC
Pfam:DHC_N2	1018	1472	4.6e-50	PFAM
Pfam:AAA_6	1652	1875	2.7e-14	PFAM
low complexity region	1906	1918	N/A	INTRINSIC
Blast:AAA	1993	2196	1e-34	BLAST
Pfam:AAA_7	2362	2610	3.3e-11	PFAM
low complexity region	2697	2714	N/A	INTRINSIC
low complexity region	2722	2733	N/A	INTRINSIC
low complexity region	2800	2810	N/A	INTRINSIC
low complexity region	3116	3134	N/A	INTRINSIC
Pfam:MT	3178	3470	3.9e-16	PFAM
coiled coil region	3590	3642	N/A	INTRINSIC
coiled coil region	3816	3843	N/A	INTRINSIC
Pfam:Dynein_heavy	3976	4746	7.3e-97	PFAM

Coding Region Coverage

1x: 99.7%
3x: 99.1%
10x: 97.6%
20x: 95.1%

Validation Efficiency

Allele List at MGI

All alleles(1) : Gene trapped(1)

Other mutations in this stock

Total: 147 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
2900092C05Rik	A	G	7: 12,288,625 (GRCm39)	E146G	probably benign	Het
Abca4	G	A	3: 121,950,081 (GRCm39)	G594S	probably damaging	Het
Acacb	T	C	5: 114,338,362 (GRCm39)	Y726H	probably damaging	Het
Adam20	T	A	8: 41,248,517 (GRCm39)	M209K	probably benign	Het
Adam29	A	G	8: 56,326,310 (GRCm39)	V48A	probably damaging	Het
Adss2	A	G	1: 177,595,253 (GRCm39)	V429A	possibly damaging	Het
Aff1	T	C	5: 103,976,320 (GRCm39)	S481P	probably damaging	Het
Akr1c19	G	A	13: 4,288,459 (GRCm39)	A146T	probably benign	Het
Ankhd1	G	T	18: 36,773,333 (GRCm39)	V59F	probably damaging	Het
Ankmy1	T	G	1: 92,816,397 (GRCm39)	Y239S	probably damaging	Het
Ankrd24	G	T	10: 81,474,142 (GRCm39)	C19F	probably damaging	Het
Apaf1	T	C	10: 90,845,065 (GRCm39)	H1002R	probably damaging	Het
Apc2	T	C	10: 80,149,935 (GRCm39)	I1663T	probably benign	Het
Apcdd1	A	G	18: 63,084,967 (GRCm39)	N388S	possibly damaging	Het
Arap2	G	A	5: 62,763,474 (GRCm39)	P1557S	possibly damaging	Het
Armc2	T	A	10: 41,798,691 (GRCm39)	H706L	probably benign	Het
Arrb1	T	C	7: 99,237,403 (GRCm39)		probably null	Het
Atl3	T	C	19: 7,507,031 (GRCm39)		probably null	Het
B9d2	A	G	7: 25,382,757 (GRCm39)	T44A	probably damaging	Het
Btbd3	C	T	2: 138,125,736 (GRCm39)	R307W	possibly damaging	Het
C1galt1	T	C	6: 7,871,193 (GRCm39)	I343T	probably benign	Het
Cacna1a	A	G	8: 85,356,460 (GRCm39)	D1901G	probably damaging	Het
Ccdc42	C	T	11: 68,488,536 (GRCm39)	Q312*	probably null	Het
Cdh18	T	C	15: 23,410,876 (GRCm39)	Y454H	probably benign	Het
Celf5	G	A	10: 81,301,839 (GRCm39)	T317I	probably damaging	Het
Celsr2	A	T	3: 108,311,211 (GRCm39)		probably null	Het
Cenpf	A	T	1: 189,414,660 (GRCm39)		probably null	Het
Cep350	T	C	1: 155,747,794 (GRCm39)	D2042G	probably damaging	Het
Chd3	T	C	11: 69,235,184 (GRCm39)	D2054G	probably damaging	Het
Chgb	A	G	2: 132,635,255 (GRCm39)	H399R	probably benign	Het
Clp1	C	T	2: 84,555,935 (GRCm39)	A182T	possibly damaging	Het
Col15a1	A	G	4: 47,282,654 (GRCm39)	N777S	probably damaging	Het
Coq6	A	G	12: 84,415,412 (GRCm39)	D145G	possibly damaging	Het
Csf2rb2	T	C	15: 78,172,108 (GRCm39)	Y325C	probably benign	Het
Ctnna2	T	C	6: 76,879,413 (GRCm39)	T824A	probably benign	Het
Cyp4x1	T	A	4: 114,970,023 (GRCm39)	D368V	probably damaging	Het
D430041D05Rik	C	T	2: 104,063,790 (GRCm39)	R1354H	probably damaging	Het
D6Ertd527e	A	C	6: 87,088,887 (GRCm39)	D350A	unknown	Het
Ddx24	A	G	12: 103,385,326 (GRCm39)	Y426H	possibly damaging	Het
Dexi	G	T	16: 10,360,426 (GRCm39)	Y43*	probably null	Het
Dgka	A	G	10: 128,556,338 (GRCm39)		probably null	Het
Dhx38	A	T	8: 110,285,575 (GRCm39)	D419E	probably benign	Het
Dlg1	G	A	16: 31,656,992 (GRCm39)	V596I	possibly damaging	Het
Dlg1	C	A	16: 31,484,398 (GRCm39)	Q9K	probably benign	Het
Dnah11	A	C	12: 118,046,246 (GRCm39)	W1731G	probably damaging	Het
Dync2h1	A	C	9: 7,051,480 (GRCm39)	S3152A	probably benign	Het
Egfl7	C	T	2: 26,479,452 (GRCm39)	T68I	probably damaging	Het
Eif2a	G	A	3: 58,463,073 (GRCm39)		probably null	Het
Emb	G	A	13: 117,369,286 (GRCm39)	V56I	possibly damaging	Het
Enpp4	A	T	17: 44,410,386 (GRCm39)	C397S	probably damaging	Het
Entpd3	A	G	9: 120,386,471 (GRCm39)	T151A	possibly damaging	Het
Ero1b	A	G	13: 12,589,747 (GRCm39)	D50G	probably damaging	Het
Fam219a	A	G	4: 41,520,242 (GRCm39)	*169Q	probably null	Het
Fga	G	A	3: 82,935,869 (GRCm39)	G32E	probably damaging	Het
Fkbpl	T	C	17: 34,864,333 (GRCm39)	F34L	probably benign	Het
Fsd2	T	A	7: 81,194,765 (GRCm39)	D466V	probably damaging	Het
Gja1	A	G	10: 56,264,166 (GRCm39)	Y175C	possibly damaging	Het
Gm5478	T	A	15: 101,553,059 (GRCm39)	I338F	probably damaging	Het
Greb1	T	A	12: 16,732,194 (GRCm39)	Y1589F	probably damaging	Het
Grk3	C	T	5: 113,067,919 (GRCm39)	E537K	probably damaging	Het
H2-K2	G	T	17: 34,218,474 (GRCm39)	D127E	probably damaging	Het
Hcrtr2	A	G	9: 76,137,966 (GRCm39)	L383P	probably benign	Het
Hmcn1	C	T	1: 150,514,651 (GRCm39)	V3574M	probably benign	Het
Ikbke	A	T	1: 131,197,921 (GRCm39)		probably null	Het
Il1r2	A	G	1: 40,144,615 (GRCm39)	K101E	probably benign	Het
Itga11	A	T	9: 62,681,653 (GRCm39)	H1054L	probably benign	Het
Kif13a	A	T	13: 46,956,187 (GRCm39)	V539D	probably damaging	Het
Kifc1	G	A	17: 34,105,621 (GRCm39)	T62I	probably damaging	Het
Klhl28	A	G	12: 64,998,529 (GRCm39)	Y322H	probably damaging	Het
Klhl6	C	A	16: 19,775,764 (GRCm39)	D265Y	possibly damaging	Het
Krt86	T	A	15: 101,377,412 (GRCm39)	C479S	unknown	Het
Lama2	C	T	10: 27,065,127 (GRCm39)	R1179H	probably benign	Het
Lce6a	A	T	3: 92,527,635 (GRCm39)	H57Q	probably benign	Het
Lcn11	T	C	2: 25,669,305 (GRCm39)	V154A	probably benign	Het
Lnpep	A	T	17: 17,758,816 (GRCm39)	F843I	probably damaging	Het
Lrrc49	C	T	9: 60,573,640 (GRCm39)	V281I	probably benign	Het
Lrrtm1	C	A	6: 77,221,611 (GRCm39)	A356E	probably damaging	Het
Map3k1	A	C	13: 111,900,044 (GRCm39)	H493Q	probably benign	Het
Mcm4	A	T	16: 15,449,979 (GRCm39)		probably null	Het
Mdn1	C	T	4: 32,712,014 (GRCm39)	P1844L	probably damaging	Het
Mdn1	T	A	4: 32,732,829 (GRCm39)	D3076E	probably benign	Het
Med6	A	T	12: 81,635,798 (GRCm39)	L27H	probably damaging	Het
Mrtfb	A	G	16: 13,199,465 (GRCm39)	E106G	probably damaging	Het
Myo7a	T	A	7: 97,721,153 (GRCm39)	T1271S	probably damaging	Het
Myo9a	T	A	9: 59,829,076 (GRCm39)	M2376K	probably benign	Het
Nell2	G	A	15: 95,127,095 (GRCm39)	T760I	probably benign	Het
Neurod6	C	T	6: 55,656,572 (GRCm39)	A22T	probably benign	Het
Nlrp10	T	C	7: 108,523,492 (GRCm39)	K663E	probably benign	Het
Nopchap1	T	C	10: 83,197,961 (GRCm39)	S56P	probably benign	Het
Npr3	T	A	15: 11,845,368 (GRCm39)	K501N	probably benign	Het
Nr2f2	C	A	7: 70,004,460 (GRCm39)	R264L	probably damaging	Het
Nup35	T	A	2: 80,472,984 (GRCm39)	M19K	probably benign	Het
Oacyl	A	T	18: 65,880,962 (GRCm39)	Q592L	possibly damaging	Het
Or10a4	T	A	7: 106,696,933 (GRCm39)	I87K	probably benign	Het
Or1ad6	C	A	11: 50,860,670 (GRCm39)	A275D	possibly damaging	Het
Or2v1	C	G	11: 49,025,549 (GRCm39)	H177D	probably damaging	Het
Or4a71	A	G	2: 89,358,451 (GRCm39)	V101A	possibly damaging	Het
Or5af1	T	A	11: 58,722,798 (GRCm39)	S273T	probably damaging	Het
Or5b105	G	A	19: 13,080,642 (GRCm39)	R3C	possibly damaging	Het
Or5b122	T	A	19: 13,563,534 (GRCm39)	Y289N	probably damaging	Het
Or5p51	A	G	7: 107,444,776 (GRCm39)	S55P	probably damaging	Het
Or6c76b	T	G	10: 129,693,070 (GRCm39)	S228A	possibly damaging	Het
Or8k25	T	A	2: 86,243,514 (GRCm39)	N294I	probably damaging	Het
Or9k7	T	C	10: 130,046,939 (GRCm39)	E20G	probably benign	Het
Patl2	T	C	2: 121,957,150 (GRCm39)	Y128C	probably benign	Het
Pcdhac2	A	G	18: 37,278,942 (GRCm39)	I641V	probably benign	Het
Polr2b	T	C	5: 77,461,006 (GRCm39)		probably benign	Het
Pot1b	A	T	17: 55,972,765 (GRCm39)	I469N	probably damaging	Het
Prdm11	G	T	2: 92,844,130 (GRCm39)	D33E	possibly damaging	Het
Prkdc	A	G	16: 15,589,921 (GRCm39)	S2595G	probably damaging	Het
Prrc1	G	A	18: 57,507,622 (GRCm39)	V259I	possibly damaging	Het
Prrc2b	G	T	2: 32,103,882 (GRCm39)	R1120L	probably damaging	Het
Prss38	T	C	11: 59,266,369 (GRCm39)	S30G	possibly damaging	Het
Raph1	A	T	1: 60,565,028 (GRCm39)	L153Q	probably damaging	Het
Reck	A	G	4: 43,940,719 (GRCm39)	T843A	probably benign	Het
Rgs7bp	T	C	13: 105,103,610 (GRCm39)	N164D	probably benign	Het
Rpusd4	C	A	9: 35,179,289 (GRCm39)	A35D	possibly damaging	Het
Setd1b	T	C	5: 123,298,014 (GRCm39)		probably benign	Het
Siglec15	G	T	18: 78,089,352 (GRCm39)	D297E	probably benign	Het
Skint7	T	A	4: 111,834,656 (GRCm39)	C13*	probably null	Het
Slc5a12	A	G	2: 110,463,088 (GRCm39)	M395V	probably benign	Het
Sohlh2	C	A	3: 55,115,104 (GRCm39)	S363Y	probably damaging	Het
Srgap3	A	T	6: 112,700,080 (GRCm39)	V966E	probably damaging	Het
Stk4	C	T	2: 163,940,462 (GRCm39)	P266L	probably damaging	Het
Stxbp5l	G	A	16: 36,962,794 (GRCm39)	H754Y	probably benign	Het
Synpo2l	A	T	14: 20,710,748 (GRCm39)	M624K	probably damaging	Het
Tas2r136	T	C	6: 132,754,375 (GRCm39)	I251V	probably benign	Het
Tecpr1	C	T	5: 144,149,408 (GRCm39)	V340M	probably damaging	Het
Tecta	C	T	9: 42,299,501 (GRCm39)	G196S	probably damaging	Het
Tex55	A	C	16: 38,648,726 (GRCm39)	S128A	probably benign	Het
Thsd7a	T	A	6: 12,331,541 (GRCm39)		probably null	Het
Timeless	T	C	10: 128,082,203 (GRCm39)	V577A	probably benign	Het
Tln1	A	T	4: 43,553,071 (GRCm39)	V340E	probably damaging	Het
Tmem132c	T	A	5: 127,640,617 (GRCm39)	Y929*	probably null	Het
Tmprss7	C	T	16: 45,489,914 (GRCm39)	R436Q	probably damaging	Het
Tnik	A	C	3: 28,704,308 (GRCm39)	K989T	probably damaging	Het
Tnxb	T	A	17: 34,890,892 (GRCm39)	Y412N	probably damaging	Het
Trmt44	A	G	5: 35,726,103 (GRCm39)		probably null	Het
Trpm6	C	A	19: 18,849,585 (GRCm39)	T1704N	probably benign	Het
Tsc2	A	T	17: 24,840,686 (GRCm39)	V391E	probably damaging	Het
Ttc22	T	C	4: 106,496,510 (GRCm39)	V520A	possibly damaging	Het
Ttc3	T	A	16: 94,257,644 (GRCm39)	Y1650*	probably null	Het
Vmn2r24	A	G	6: 123,763,893 (GRCm39)	T257A	probably benign	Het
Xab2	A	C	8: 3,663,605 (GRCm39)	N408K	probably benign	Het
Zbtb42	A	T	12: 112,647,061 (GRCm39)	Y412F	probably benign	Het
Zfp282	A	G	6: 47,857,303 (GRCm39)	N179D	probably damaging	Het
Zfp62	C	A	11: 49,106,227 (GRCm39)	T106K	probably benign	Het

Other mutations in Dnhd1

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00321:Dnhd1	APN	7	105,327,202 (GRCm39)	missense	probably damaging	1.00
IGL00516:Dnhd1	APN	7	105,306,418 (GRCm39)	missense	possibly damaging	0.52
IGL00576:Dnhd1	APN	7	105,341,882 (GRCm39)	missense	probably damaging	1.00
IGL00990:Dnhd1	APN	7	105,370,895 (GRCm39)	missense	possibly damaging	0.85
IGL01346:Dnhd1	APN	7	105,363,116 (GRCm39)	missense	probably benign
IGL01714:Dnhd1	APN	7	105,370,149 (GRCm39)	missense	probably damaging	1.00
IGL01735:Dnhd1	APN	7	105,362,961 (GRCm39)	missense	probably benign	0.37
IGL01814:Dnhd1	APN	7	105,301,237 (GRCm39)	missense	probably benign
IGL01999:Dnhd1	APN	7	105,370,422 (GRCm39)	missense	possibly damaging	0.50
IGL02022:Dnhd1	APN	7	105,327,516 (GRCm39)	missense	probably damaging	1.00
IGL02131:Dnhd1	APN	7	105,370,009 (GRCm39)	missense	probably damaging	1.00
IGL02156:Dnhd1	APN	7	105,370,951 (GRCm39)	missense	probably damaging	1.00
IGL02674:Dnhd1	APN	7	105,370,688 (GRCm39)	missense	probably benign	0.00
IGL02966:Dnhd1	APN	7	105,369,948 (GRCm39)	missense	probably benign	0.00
IGL03066:Dnhd1	APN	7	105,369,089 (GRCm39)	missense	probably damaging	0.99
IGL03298:Dnhd1	APN	7	105,363,682 (GRCm39)	missense	probably damaging	0.98
IGL03378:Dnhd1	APN	7	105,362,940 (GRCm39)	missense	possibly damaging	0.87
IGL02802:Dnhd1	UTSW	7	105,304,930 (GRCm39)	missense	possibly damaging	0.83
R0060:Dnhd1	UTSW	7	105,317,721 (GRCm39)	missense	probably damaging	0.99
R0129:Dnhd1	UTSW	7	105,370,131 (GRCm39)	missense	probably benign	0.19
R0238:Dnhd1	UTSW	7	105,370,738 (GRCm39)	missense	probably benign	0.06
R0238:Dnhd1	UTSW	7	105,370,738 (GRCm39)	missense	probably benign	0.06
R0239:Dnhd1	UTSW	7	105,370,738 (GRCm39)	missense	probably benign	0.06
R0239:Dnhd1	UTSW	7	105,370,738 (GRCm39)	missense	probably benign	0.06
R0384:Dnhd1	UTSW	7	105,369,321 (GRCm39)	missense	possibly damaging	0.56
R0453:Dnhd1	UTSW	7	105,323,651 (GRCm39)	missense	probably benign	0.00
R0540:Dnhd1	UTSW	7	105,369,995 (GRCm39)	missense	probably benign	0.04
R0554:Dnhd1	UTSW	7	105,343,602 (GRCm39)	missense	probably benign	0.10
R0576:Dnhd1	UTSW	7	105,363,252 (GRCm39)	missense	probably damaging	1.00
R0631:Dnhd1	UTSW	7	105,300,831 (GRCm39)	missense	probably benign	0.17
R0639:Dnhd1	UTSW	7	105,345,671 (GRCm39)	missense	possibly damaging	0.95
R0668:Dnhd1	UTSW	7	105,344,958 (GRCm39)	missense	probably benign
R0669:Dnhd1	UTSW	7	105,342,911 (GRCm39)	missense	probably benign	0.01
R0670:Dnhd1	UTSW	7	105,345,671 (GRCm39)	missense	possibly damaging	0.95
R0699:Dnhd1	UTSW	7	105,301,113 (GRCm39)	missense	probably damaging	0.98
R1019:Dnhd1	UTSW	7	105,358,378 (GRCm39)	missense	probably damaging	1.00
R1144:Dnhd1	UTSW	7	105,362,238 (GRCm39)	missense	probably damaging	1.00
R1226:Dnhd1	UTSW	7	105,346,106 (GRCm39)	missense	probably damaging	1.00
R1257:Dnhd1	UTSW	7	105,343,360 (GRCm39)	missense	probably damaging	1.00
R1391:Dnhd1	UTSW	7	105,369,331 (GRCm39)	missense	probably damaging	1.00
R1453:Dnhd1	UTSW	7	105,370,480 (GRCm39)	critical splice donor site	probably null
R1501:Dnhd1	UTSW	7	105,317,670 (GRCm39)	missense	probably benign	0.00
R1503:Dnhd1	UTSW	7	105,342,867 (GRCm39)	missense	possibly damaging	0.67
R1515:Dnhd1	UTSW	7	105,353,355 (GRCm39)	missense	probably benign	0.11
R1615:Dnhd1	UTSW	7	105,362,913 (GRCm39)	missense	possibly damaging	0.74
R1615:Dnhd1	UTSW	7	105,352,413 (GRCm39)	missense	probably benign	0.00
R1656:Dnhd1	UTSW	7	105,363,488 (GRCm39)	missense	probably damaging	1.00
R1720:Dnhd1	UTSW	7	105,343,035 (GRCm39)	missense	probably benign
R1723:Dnhd1	UTSW	7	105,364,127 (GRCm39)	missense	possibly damaging	0.60
R1766:Dnhd1	UTSW	7	105,343,179 (GRCm39)	missense	possibly damaging	0.50
R1799:Dnhd1	UTSW	7	105,304,974 (GRCm39)	missense	probably benign	0.31
R1860:Dnhd1	UTSW	7	105,353,412 (GRCm39)	missense	probably benign
R1920:Dnhd1	UTSW	7	105,362,614 (GRCm39)	missense	probably benign	0.00
R1925:Dnhd1	UTSW	7	105,323,061 (GRCm39)	missense	probably damaging	0.96
R1925:Dnhd1	UTSW	7	105,301,459 (GRCm39)	missense	probably damaging	1.00
R1934:Dnhd1	UTSW	7	105,357,789 (GRCm39)	missense	probably benign	0.05
R1935:Dnhd1	UTSW	7	105,323,183 (GRCm39)	missense	probably benign	0.09
R1936:Dnhd1	UTSW	7	105,323,183 (GRCm39)	missense	probably benign	0.09
R2035:Dnhd1	UTSW	7	105,354,128 (GRCm39)	missense	probably damaging	0.99
R2125:Dnhd1	UTSW	7	105,327,178 (GRCm39)	missense	probably benign	0.35
R2127:Dnhd1	UTSW	7	105,342,928 (GRCm39)	missense	possibly damaging	0.56
R2254:Dnhd1	UTSW	7	105,352,979 (GRCm39)	missense	probably damaging	1.00
R2301:Dnhd1	UTSW	7	105,354,606 (GRCm39)	missense	probably damaging	1.00
R2316:Dnhd1	UTSW	7	105,323,628 (GRCm39)	missense	probably damaging	1.00
R2324:Dnhd1	UTSW	7	105,359,297 (GRCm39)	missense	probably damaging	1.00
R2337:Dnhd1	UTSW	7	105,352,674 (GRCm39)	missense	probably benign	0.07
R2381:Dnhd1	UTSW	7	105,342,871 (GRCm39)	missense	probably benign	0.42
R2394:Dnhd1	UTSW	7	105,369,438 (GRCm39)	missense	probably benign	0.19
R2862:Dnhd1	UTSW	7	105,361,766 (GRCm39)	missense	probably benign	0.01
R3038:Dnhd1	UTSW	7	105,369,436 (GRCm39)	missense	probably damaging	0.99
R3114:Dnhd1	UTSW	7	105,345,772 (GRCm39)	critical splice donor site	probably null
R3404:Dnhd1	UTSW	7	105,343,968 (GRCm39)	nonsense	probably null
R3405:Dnhd1	UTSW	7	105,343,968 (GRCm39)	nonsense	probably null
R3439:Dnhd1	UTSW	7	105,343,992 (GRCm39)	missense	probably damaging	1.00
R3959:Dnhd1	UTSW	7	105,362,329 (GRCm39)	missense	probably benign	0.21
R4014:Dnhd1	UTSW	7	105,364,045 (GRCm39)	missense	probably damaging	0.99
R4084:Dnhd1	UTSW	7	105,358,795 (GRCm39)	missense	probably damaging	1.00
R4181:Dnhd1	UTSW	7	105,343,161 (GRCm39)	missense	probably damaging	1.00
R4255:Dnhd1	UTSW	7	105,362,205 (GRCm39)	missense	probably damaging	1.00
R4302:Dnhd1	UTSW	7	105,343,161 (GRCm39)	missense	probably damaging	1.00
R4440:Dnhd1	UTSW	7	105,345,935 (GRCm39)	nonsense	probably null
R4565:Dnhd1	UTSW	7	105,301,163 (GRCm39)	missense	possibly damaging	0.92
R4569:Dnhd1	UTSW	7	105,306,373 (GRCm39)	splice site	probably null
R4584:Dnhd1	UTSW	7	105,327,256 (GRCm39)	missense	probably damaging	1.00
R4586:Dnhd1	UTSW	7	105,327,256 (GRCm39)	missense	probably damaging	1.00
R4590:Dnhd1	UTSW	7	105,363,237 (GRCm39)	missense	probably damaging	1.00
R4593:Dnhd1	UTSW	7	105,364,653 (GRCm39)	missense	probably benign	0.02
R4600:Dnhd1	UTSW	7	105,352,851 (GRCm39)	missense	probably damaging	1.00
R4705:Dnhd1	UTSW	7	105,304,948 (GRCm39)	missense	probably damaging	1.00
R4731:Dnhd1	UTSW	7	105,323,056 (GRCm39)	missense	probably benign	0.00
R4732:Dnhd1	UTSW	7	105,323,056 (GRCm39)	missense	probably benign	0.00
R4733:Dnhd1	UTSW	7	105,323,056 (GRCm39)	missense	probably benign	0.00
R4786:Dnhd1	UTSW	7	105,323,651 (GRCm39)	missense	probably benign	0.00
R4791:Dnhd1	UTSW	7	105,370,324 (GRCm39)	missense	probably damaging	1.00
R4811:Dnhd1	UTSW	7	105,363,488 (GRCm39)	missense	probably damaging	0.99
R4822:Dnhd1	UTSW	7	105,353,171 (GRCm39)	missense	probably benign	0.00
R4886:Dnhd1	UTSW	7	105,364,015 (GRCm39)	missense	probably benign	0.00
R4890:Dnhd1	UTSW	7	105,306,164 (GRCm39)	missense	possibly damaging	0.47
R4973:Dnhd1	UTSW	7	105,362,840 (GRCm39)	missense	probably benign	0.24
R5007:Dnhd1	UTSW	7	105,362,283 (GRCm39)	missense	probably damaging	1.00
R5048:Dnhd1	UTSW	7	105,342,904 (GRCm39)	missense	probably benign	0.01
R5151:Dnhd1	UTSW	7	105,362,647 (GRCm39)	missense	probably benign	0.22
R5179:Dnhd1	UTSW	7	105,363,759 (GRCm39)	missense	probably damaging	1.00
R5182:Dnhd1	UTSW	7	105,352,416 (GRCm39)	missense	probably damaging	1.00
R5183:Dnhd1	UTSW	7	105,352,416 (GRCm39)	missense	probably damaging	1.00
R5185:Dnhd1	UTSW	7	105,352,416 (GRCm39)	missense	probably damaging	1.00
R5209:Dnhd1	UTSW	7	105,345,667 (GRCm39)	missense	probably benign	0.00
R5225:Dnhd1	UTSW	7	105,353,130 (GRCm39)	missense	possibly damaging	0.73
R5250:Dnhd1	UTSW	7	105,334,968 (GRCm39)	missense	probably damaging	1.00
R5257:Dnhd1	UTSW	7	105,323,244 (GRCm39)	missense	probably benign
R5258:Dnhd1	UTSW	7	105,323,244 (GRCm39)	missense	probably benign
R5273:Dnhd1	UTSW	7	105,363,689 (GRCm39)	missense	probably damaging	0.99
R5288:Dnhd1	UTSW	7	105,363,644 (GRCm39)	missense	possibly damaging	0.94
R5396:Dnhd1	UTSW	7	105,362,891 (GRCm39)	missense	probably benign	0.00
R5453:Dnhd1	UTSW	7	105,359,330 (GRCm39)	missense	probably damaging	1.00
R5511:Dnhd1	UTSW	7	105,363,363 (GRCm39)	missense	probably damaging	1.00
R5518:Dnhd1	UTSW	7	105,352,416 (GRCm39)	missense	probably damaging	1.00
R5523:Dnhd1	UTSW	7	105,352,416 (GRCm39)	missense	probably damaging	1.00
R5528:Dnhd1	UTSW	7	105,352,416 (GRCm39)	missense	probably damaging	1.00
R5529:Dnhd1	UTSW	7	105,352,416 (GRCm39)	missense	probably damaging	1.00
R5561:Dnhd1	UTSW	7	105,364,028 (GRCm39)	missense	probably damaging	0.99
R5681:Dnhd1	UTSW	7	105,352,416 (GRCm39)	missense	probably damaging	1.00
R5682:Dnhd1	UTSW	7	105,352,416 (GRCm39)	missense	probably damaging	1.00
R5683:Dnhd1	UTSW	7	105,352,416 (GRCm39)	missense	probably damaging	1.00
R5684:Dnhd1	UTSW	7	105,352,416 (GRCm39)	missense	probably damaging	1.00
R5686:Dnhd1	UTSW	7	105,352,416 (GRCm39)	missense	probably damaging	1.00
R5697:Dnhd1	UTSW	7	105,323,395 (GRCm39)	missense	probably damaging	1.00
R5789:Dnhd1	UTSW	7	105,354,217 (GRCm39)	missense	possibly damaging	0.50
R5790:Dnhd1	UTSW	7	105,304,981 (GRCm39)	missense	probably damaging	1.00
R5814:Dnhd1	UTSW	7	105,369,102 (GRCm39)	missense	possibly damaging	0.69
R5828:Dnhd1	UTSW	7	105,369,388 (GRCm39)	missense	probably benign	0.00
R5852:Dnhd1	UTSW	7	105,344,955 (GRCm39)	missense	probably damaging	1.00
R5883:Dnhd1	UTSW	7	105,369,711 (GRCm39)	missense	probably damaging	0.98
R6115:Dnhd1	UTSW	7	105,363,194 (GRCm39)	missense	probably benign	0.00
R6119:Dnhd1	UTSW	7	105,358,647 (GRCm39)	missense	probably benign	0.18
R6212:Dnhd1	UTSW	7	105,353,255 (GRCm39)	missense	probably damaging	1.00
R6243:Dnhd1	UTSW	7	105,301,216 (GRCm39)	missense	probably damaging	1.00
R6265:Dnhd1	UTSW	7	105,342,577 (GRCm39)	missense	probably benign	0.07
R6332:Dnhd1	UTSW	7	105,343,273 (GRCm39)	missense	probably benign	0.02
R6344:Dnhd1	UTSW	7	105,343,817 (GRCm39)	missense	probably benign	0.38
R6477:Dnhd1	UTSW	7	105,327,093 (GRCm39)	missense	probably benign	0.05
R6642:Dnhd1	UTSW	7	105,353,006 (GRCm39)	missense	probably benign
R6663:Dnhd1	UTSW	7	105,334,899 (GRCm39)	splice site	probably null
R6730:Dnhd1	UTSW	7	105,353,082 (GRCm39)	missense	probably benign	0.00
R6748:Dnhd1	UTSW	7	105,369,844 (GRCm39)	missense	probably benign	0.03
R6833:Dnhd1	UTSW	7	105,352,580 (GRCm39)	missense	probably benign	0.01
R6850:Dnhd1	UTSW	7	105,369,137 (GRCm39)	missense	possibly damaging	0.68
R6853:Dnhd1	UTSW	7	105,352,935 (GRCm39)	missense	probably benign
R6860:Dnhd1	UTSW	7	105,327,473 (GRCm39)	missense	probably benign
R6898:Dnhd1	UTSW	7	105,336,584 (GRCm39)	missense	probably damaging	0.99
R6927:Dnhd1	UTSW	7	105,364,770 (GRCm39)	missense	probably damaging	1.00
R6952:Dnhd1	UTSW	7	105,362,895 (GRCm39)	missense	probably damaging	1.00
R6987:Dnhd1	UTSW	7	105,353,792 (GRCm39)	missense	probably damaging	0.98
R6988:Dnhd1	UTSW	7	105,363,417 (GRCm39)	missense	probably damaging	1.00
R7022:Dnhd1	UTSW	7	105,370,005 (GRCm39)	missense	probably benign	0.36
R7053:Dnhd1	UTSW	7	105,344,161 (GRCm39)	missense	probably damaging	1.00
R7085:Dnhd1	UTSW	7	105,364,468 (GRCm39)	missense	probably benign	0.26
R7086:Dnhd1	UTSW	7	105,357,739 (GRCm39)	missense	probably benign	0.03
R7112:Dnhd1	UTSW	7	105,363,192 (GRCm39)	missense	probably damaging	1.00
R7140:Dnhd1	UTSW	7	105,342,973 (GRCm39)	missense	probably benign	0.00
R7151:Dnhd1	UTSW	7	105,359,234 (GRCm39)	missense	probably benign	0.03
R7178:Dnhd1	UTSW	7	105,344,200 (GRCm39)	missense	probably damaging	0.98
R7326:Dnhd1	UTSW	7	105,370,137 (GRCm39)	missense	probably damaging	0.96
R7345:Dnhd1	UTSW	7	105,353,174 (GRCm39)	missense	probably benign	0.17
R7349:Dnhd1	UTSW	7	105,359,330 (GRCm39)	missense	probably damaging	1.00
R7397:Dnhd1	UTSW	7	105,354,504 (GRCm39)	missense	possibly damaging	0.87
R7520:Dnhd1	UTSW	7	105,345,255 (GRCm39)	missense	probably benign	0.07
R7536:Dnhd1	UTSW	7	105,358,768 (GRCm39)	missense	probably damaging	1.00
R7539:Dnhd1	UTSW	7	105,370,119 (GRCm39)	missense	probably damaging	1.00
R7541:Dnhd1	UTSW	7	105,327,516 (GRCm39)	missense	probably damaging	1.00
R7619:Dnhd1	UTSW	7	105,323,475 (GRCm39)	missense	probably benign	0.01
R7676:Dnhd1	UTSW	7	105,333,294 (GRCm39)	missense	probably benign	0.09
R7689:Dnhd1	UTSW	7	105,363,170 (GRCm39)	missense	probably benign	0.07
R7712:Dnhd1	UTSW	7	105,300,831 (GRCm39)	missense	probably benign	0.17
R7729:Dnhd1	UTSW	7	105,354,472 (GRCm39)	missense	probably damaging	1.00
R7767:Dnhd1	UTSW	7	105,343,817 (GRCm39)	missense	probably benign	0.38
R7768:Dnhd1	UTSW	7	105,370,302 (GRCm39)	missense	possibly damaging	0.87
R7779:Dnhd1	UTSW	7	105,327,122 (GRCm39)	missense	probably benign	0.01
R7879:Dnhd1	UTSW	7	105,352,646 (GRCm39)	missense	probably benign	0.09
R7922:Dnhd1	UTSW	7	105,317,721 (GRCm39)	missense	probably damaging	1.00
R7951:Dnhd1	UTSW	7	105,327,211 (GRCm39)	missense	probably damaging	1.00
R8259:Dnhd1	UTSW	7	105,343,995 (GRCm39)	missense	probably benign	0.38
R8350:Dnhd1	UTSW	7	105,327,231 (GRCm39)	missense	probably damaging	0.99
R8380:Dnhd1	UTSW	7	105,327,073 (GRCm39)	missense	probably benign	0.31
R8392:Dnhd1	UTSW	7	105,352,550 (GRCm39)	missense	possibly damaging	0.84
R8478:Dnhd1	UTSW	7	105,332,001 (GRCm39)	missense	probably benign	0.00
R8708:Dnhd1	UTSW	7	105,343,487 (GRCm39)	nonsense	probably null
R8767:Dnhd1	UTSW	7	105,301,330 (GRCm39)	missense	probably damaging	1.00
R8825:Dnhd1	UTSW	7	105,343,174 (GRCm39)	missense	possibly damaging	0.95
R8849:Dnhd1	UTSW	7	105,370,723 (GRCm39)	missense	probably benign	0.00
R8903:Dnhd1	UTSW	7	105,362,855 (GRCm39)	nonsense	probably null
R8910:Dnhd1	UTSW	7	105,332,904 (GRCm39)	missense	possibly damaging	0.92
R8940:Dnhd1	UTSW	7	105,363,854 (GRCm39)	intron	probably benign
R8954:Dnhd1	UTSW	7	105,343,986 (GRCm39)	missense	probably benign	0.35
R8956:Dnhd1	UTSW	7	105,341,852 (GRCm39)	missense	probably damaging	0.99
R8971:Dnhd1	UTSW	7	105,358,528 (GRCm39)	nonsense	probably null
R8996:Dnhd1	UTSW	7	105,323,242 (GRCm39)	missense	probably damaging	1.00
R9051:Dnhd1	UTSW	7	105,341,933 (GRCm39)	missense	possibly damaging	0.54
R9058:Dnhd1	UTSW	7	105,333,270 (GRCm39)	missense	probably benign	0.01
R9109:Dnhd1	UTSW	7	105,333,173 (GRCm39)	missense	probably damaging	0.98
R9284:Dnhd1	UTSW	7	105,301,091 (GRCm39)	missense	probably damaging	1.00
R9295:Dnhd1	UTSW	7	105,363,348 (GRCm39)	missense	probably benign
R9298:Dnhd1	UTSW	7	105,333,173 (GRCm39)	missense	probably damaging	0.98
R9299:Dnhd1	UTSW	7	105,369,806 (GRCm39)	missense	probably benign	0.00
R9308:Dnhd1	UTSW	7	105,353,484 (GRCm39)	missense	probably damaging	1.00
R9337:Dnhd1	UTSW	7	105,369,806 (GRCm39)	missense	probably benign	0.00
R9385:Dnhd1	UTSW	7	105,361,972 (GRCm39)	missense	probably damaging	1.00
R9463:Dnhd1	UTSW	7	105,344,223 (GRCm39)	missense	probably benign
R9463:Dnhd1	UTSW	7	105,306,454 (GRCm39)	missense	probably benign	0.00
R9476:Dnhd1	UTSW	7	105,352,889 (GRCm39)	missense	possibly damaging	0.74
R9489:Dnhd1	UTSW	7	105,300,804 (GRCm39)	missense	probably benign
R9500:Dnhd1	UTSW	7	105,353,709 (GRCm39)	missense	probably benign
R9510:Dnhd1	UTSW	7	105,352,889 (GRCm39)	missense	possibly damaging	0.74
R9513:Dnhd1	UTSW	7	105,354,179 (GRCm39)	missense	probably damaging	1.00
R9537:Dnhd1	UTSW	7	105,344,740 (GRCm39)	missense	probably damaging	0.99
R9567:Dnhd1	UTSW	7	105,353,473 (GRCm39)	missense	probably benign	0.03
R9622:Dnhd1	UTSW	7	105,353,342 (GRCm39)	missense	probably benign
R9623:Dnhd1	UTSW	7	105,344,134 (GRCm39)	missense	probably damaging	1.00
R9623:Dnhd1	UTSW	7	105,335,773 (GRCm39)	missense	probably damaging	1.00
R9674:Dnhd1	UTSW	7	105,363,429 (GRCm39)	missense	probably damaging	1.00
R9756:Dnhd1	UTSW	7	105,353,135 (GRCm39)	missense	probably benign	0.19
R9777:Dnhd1	UTSW	7	105,369,456 (GRCm39)	missense	probably benign	0.14
R9778:Dnhd1	UTSW	7	105,353,240 (GRCm39)	missense	probably benign
R9781:Dnhd1	UTSW	7	105,352,917 (GRCm39)	missense	probably benign	0.31
R9796:Dnhd1	UTSW	7	105,342,537 (GRCm39)	missense	probably damaging	1.00
Z1088:Dnhd1	UTSW	7	105,361,934 (GRCm39)	missense	probably benign	0.00
Z1176:Dnhd1	UTSW	7	105,352,243 (GRCm39)	critical splice acceptor site	probably null
Z1176:Dnhd1	UTSW	7	105,327,506 (GRCm39)	missense	probably benign
Z1176:Dnhd1	UTSW	7	105,317,754 (GRCm39)	missense	probably damaging	0.98
Z1176:Dnhd1	UTSW	7	105,352,787 (GRCm39)	frame shift	probably null
Z1177:Dnhd1	UTSW	7	105,332,048 (GRCm39)	missense	possibly damaging	0.90

Predicted Primers

PCR Primer
(F):5'- AGTTTGTGGAGGAATTGCCCAGC -3'
(R):5'- GTCCAGGTAGCGAATCAACAGGTG -3'

Sequencing Primer
(F):5'- GAATTGCCCAGCGCAAAG -3'
(R):5'- TCTCCAAGGCTGAGGTAGG -3'

Posted On

2013-07-11