Incidental Mutation 'R7009:Copa'
| ID |
544872 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Copa
|
| Ensembl Gene |
ENSMUSG00000026553 |
| Gene Name |
coatomer protein complex subunit alpha |
| Synonyms |
xenin |
| MMRRC Submission |
045111-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably essential
(E-score: 0.971)
|
| Stock # |
R7009 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
1 |
| Chromosomal Location |
172082529-172122330 bp(+) (GRCm38) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
G to T
at 172091000 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Arginine to Leucine
at position 97
(R97L)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000118179
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000027833]
[ENSMUST00000124289]
[ENSMUST00000135192]
|
| AlphaFold |
Q8CIE6 |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000027833
AA Change: R97L
PolyPhen 2
Score 0.910 (Sensitivity: 0.81; Specificity: 0.94)
|
| SMART Domains |
Protein: ENSMUSP00000027833
Gene: ENSMUSG00000026553
AA Change: R97L
| Domain | Start | End | E-Value | Type |
|---|
|
WD40
|
2 |
37 |
2.86e0 |
SMART |
|
WD40
|
40 |
79 |
1.11e-6 |
SMART |
|
WD40
|
82 |
121 |
4.76e-6 |
SMART |
|
WD40
|
124 |
163 |
2.24e-11 |
SMART |
|
WD40
|
194 |
233 |
2.98e-7 |
SMART |
|
WD40
|
238 |
277 |
8.42e-7 |
SMART |
|
WD40
|
280 |
318 |
1.38e1 |
SMART |
|
Pfam:Coatomer_WDAD
|
338 |
776 |
5.4e-144 |
PFAM |
|
Pfam:COPI_C
|
824 |
1233 |
1.4e-190 |
PFAM |
|
| Predicted Effect |
silent
Transcript: ENSMUST00000124289
|
| SMART Domains |
Protein: ENSMUSP00000118899
Gene: ENSMUSG00000026553
| Domain | Start | End | E-Value | Type |
|---|
|
Blast:WD40
|
1 |
37 |
2e-19 |
BLAST |
|
PDB:4J8G|B
|
1 |
52 |
2e-23 |
PDB |
|
SCOP:d1erja_
|
1 |
52 |
1e-6 |
SMART |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000135192
AA Change: R97L
PolyPhen 2
Score 0.961 (Sensitivity: 0.78; Specificity: 0.95)
|
| SMART Domains |
Protein: ENSMUSP00000118179
Gene: ENSMUSG00000026553
AA Change: R97L
| Domain | Start | End | E-Value | Type |
|---|
|
WD40
|
2 |
37 |
2.86e0 |
SMART |
|
WD40
|
40 |
79 |
1.11e-6 |
SMART |
|
WD40
|
82 |
121 |
4.76e-6 |
SMART |
|
WD40
|
124 |
163 |
2.24e-11 |
SMART |
|
WD40
|
194 |
233 |
2.98e-7 |
SMART |
|
WD40
|
238 |
277 |
8.42e-7 |
SMART |
|
WD40
|
280 |
318 |
1.38e1 |
SMART |
|
Pfam:Coatomer_WDAD
|
338 |
767 |
1.1e-148 |
PFAM |
|
Pfam:COPI_C
|
815 |
1224 |
3.6e-216 |
PFAM |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 100.0%
- 10x: 99.8%
- 20x: 99.2%
|
| Validation Efficiency |
99% (82/83) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] In eukaryotic cells, protein transport between the endoplasmic reticulum and Golgi compartments is mediated in part by non-clathrin-coated vesicular coat proteins (COPs). Seven coat proteins have been identified, and they represent subunits of a complex known as coatomer. The subunits are designated alpha-COP, beta-COP, beta-prime-COP, gamma-COP, delta-COP, epsilon-COP, and zeta-COP. The alpha-COP, encoded by COPA, shares high sequence similarity with RET1P, the alpha subunit of the coatomer complex in yeast. Also, the N-terminal 25 amino acids of alpha-COP encode the bioactive peptide, xenin, which stimulates exocrine pancreatic secretion and may act as a gastrointestinal hormone. Alternative splicing results in multiple splice forms encoding distinct isoforms. [provided by RefSeq, Jul 2008]
|
| Allele List at MGI |
All alleles(6) : Gene trapped(6)
|
| Other mutations in this stock |
Total: 83 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4921517D22Rik |
G |
T |
13: 59,690,810 (GRCm38) |
D69E |
possibly damaging |
Het |
| Abat |
A |
C |
16: 8,602,367 (GRCm38) |
M177L |
probably benign |
Het |
| Acadvl |
A |
G |
11: 70,014,791 (GRCm38) |
|
probably null |
Het |
| Adam5 |
T |
C |
8: 24,806,438 (GRCm38) |
N331S |
probably benign |
Het |
| Ager |
A |
G |
17: 34,600,736 (GRCm38) |
E372G |
probably damaging |
Het |
| Angpt1 |
T |
A |
15: 42,523,595 (GRCm38) |
Q121L |
possibly damaging |
Het |
| Apoa4 |
A |
T |
9: 46,242,880 (GRCm38) |
I260F |
possibly damaging |
Het |
| Arhgap32 |
A |
T |
9: 32,245,976 (GRCm38) |
I90F |
probably damaging |
Het |
| Arhgap5 |
A |
T |
12: 52,519,639 (GRCm38) |
Q1131L |
probably benign |
Het |
| Bach1 |
G |
A |
16: 87,719,291 (GRCm38) |
R240Q |
probably benign |
Het |
| Cacna2d3 |
A |
T |
14: 28,969,365 (GRCm38) |
M1K |
probably null |
Het |
| Ccdc18 |
G |
A |
5: 108,173,862 (GRCm38) |
|
probably null |
Het |
| Ccdc42 |
T |
C |
11: 68,594,616 (GRCm38) |
F267S |
probably damaging |
Het |
| Cdh23 |
T |
A |
10: 60,337,306 (GRCm38) |
Y1700F |
probably damaging |
Het |
| Cenpe |
A |
T |
3: 135,235,201 (GRCm38) |
S704C |
probably damaging |
Het |
| Cenpe |
G |
A |
3: 135,235,202 (GRCm38) |
S704N |
probably benign |
Het |
| Cfap299 |
A |
T |
5: 98,784,520 (GRCm38) |
D193V |
probably damaging |
Het |
| Cfap54 |
A |
T |
10: 92,875,019 (GRCm38) |
S2727T |
unknown |
Het |
| Clu |
T |
A |
14: 65,971,832 (GRCm38) |
V113D |
probably damaging |
Het |
| Cnbd2 |
A |
G |
2: 156,320,034 (GRCm38) |
I98V |
probably benign |
Het |
| Epb41l1 |
C |
A |
2: 156,534,683 (GRCm38) |
|
probably null |
Het |
| Etnk1 |
T |
A |
6: 143,203,154 (GRCm38) |
|
probably null |
Het |
| Fnip1 |
A |
T |
11: 54,502,935 (GRCm38) |
K732N |
probably damaging |
Het |
| G6pd2 |
A |
G |
5: 61,808,891 (GRCm38) |
E3G |
probably benign |
Het |
| Gal3st2 |
A |
G |
1: 93,873,759 (GRCm38) |
T95A |
probably benign |
Het |
| Gapvd1 |
A |
G |
2: 34,700,817 (GRCm38) |
S948P |
probably damaging |
Het |
| Ggps1 |
A |
T |
13: 14,054,165 (GRCm38) |
Y8* |
probably null |
Het |
| Gria2 |
T |
C |
3: 80,706,972 (GRCm38) |
E587G |
probably damaging |
Het |
| Hpse |
T |
C |
5: 100,692,279 (GRCm38) |
E324G |
probably benign |
Het |
| Il16 |
G |
A |
7: 83,646,388 (GRCm38) |
T493I |
probably benign |
Het |
| Ints1 |
T |
C |
5: 139,768,462 (GRCm38) |
T652A |
possibly damaging |
Het |
| Ism1 |
A |
G |
2: 139,757,279 (GRCm38) |
I391V |
probably damaging |
Het |
| Katnb1 |
A |
G |
8: 95,098,384 (GRCm38) |
D598G |
probably damaging |
Het |
| Kif5c |
A |
G |
2: 49,757,429 (GRCm38) |
S880G |
probably benign |
Het |
| Klra8 |
T |
C |
6: 130,125,184 (GRCm38) |
N96S |
probably benign |
Het |
| Krt79 |
T |
A |
15: 101,931,441 (GRCm38) |
D373V |
probably damaging |
Het |
| Lamtor4 |
G |
A |
5: 138,259,112 (GRCm38) |
R92Q |
probably benign |
Het |
| Lce1d |
C |
A |
3: 92,686,046 (GRCm38) |
C20F |
unknown |
Het |
| Limk1 |
T |
C |
5: 134,672,699 (GRCm38) |
T117A |
probably benign |
Het |
| Medag |
A |
T |
5: 149,427,243 (GRCm38) |
K61M |
probably benign |
Het |
| Mkrn3 |
T |
C |
7: 62,419,618 (GRCm38) |
M142V |
probably benign |
Het |
| Mob3c |
G |
A |
4: 115,831,582 (GRCm38) |
R104H |
probably benign |
Het |
| Morc1 |
G |
T |
16: 48,627,070 (GRCm38) |
R903L |
possibly damaging |
Het |
| Myh6 |
T |
C |
14: 54,952,292 (GRCm38) |
E1099G |
probably damaging |
Het |
| Nphp3 |
T |
G |
9: 104,016,116 (GRCm38) |
C434G |
probably null |
Het |
| Npr3 |
C |
T |
15: 11,905,248 (GRCm38) |
C131Y |
probably damaging |
Het |
| Oacyl |
C |
A |
18: 65,722,538 (GRCm38) |
Y112* |
probably null |
Het |
| Oprl1 |
A |
G |
2: 181,718,381 (GRCm38) |
T77A |
probably damaging |
Het |
| Osgep |
A |
G |
14: 50,924,708 (GRCm38) |
V24A |
probably damaging |
Het |
| Otx2 |
T |
A |
14: 48,658,797 (GRCm38) |
K260M |
probably damaging |
Het |
| Pdcd11 |
T |
C |
19: 47,113,142 (GRCm38) |
L922P |
probably benign |
Het |
| Pgap4 |
A |
T |
4: 49,586,325 (GRCm38) |
M281K |
probably benign |
Het |
| Phldb1 |
A |
G |
9: 44,694,408 (GRCm38) |
V375A |
probably damaging |
Het |
| Pip5k1b |
C |
T |
19: 24,359,935 (GRCm38) |
|
probably null |
Het |
| Psmd3 |
G |
A |
11: 98,682,766 (GRCm38) |
D13N |
probably benign |
Het |
| Ptprc |
G |
A |
1: 138,064,553 (GRCm38) |
H1140Y |
probably damaging |
Het |
| Ranbp3l |
A |
T |
15: 9,062,984 (GRCm38) |
H291L |
probably damaging |
Het |
| Rasa4 |
T |
A |
5: 136,101,363 (GRCm38) |
D324E |
probably damaging |
Het |
| Rilpl1 |
T |
A |
5: 124,503,692 (GRCm38) |
|
silent |
Het |
| Rin2 |
A |
C |
2: 145,883,475 (GRCm38) |
D794A |
probably damaging |
Het |
| Ripk1 |
A |
G |
13: 34,030,062 (GRCm38) |
I522M |
probably damaging |
Het |
| Rnf31 |
T |
C |
14: 55,592,551 (GRCm38) |
Y143H |
probably benign |
Het |
| Rp1 |
T |
G |
1: 4,042,068 (GRCm38) |
I1187L |
unknown |
Het |
| Rps6ka5 |
G |
A |
12: 100,619,537 (GRCm38) |
H166Y |
probably damaging |
Het |
| Rrm1 |
T |
C |
7: 102,460,334 (GRCm38) |
V455A |
probably damaging |
Het |
| Runx2 |
G |
A |
17: 44,814,192 (GRCm38) |
P80L |
probably damaging |
Het |
| Scn5a |
T |
G |
9: 119,485,930 (GRCm38) |
E1904A |
probably damaging |
Het |
| Sec16a |
G |
T |
2: 26,436,002 (GRCm38) |
S240* |
probably null |
Het |
| Slc22a8 |
C |
T |
19: 8,605,417 (GRCm38) |
T154I |
probably benign |
Het |
| Slc25a16 |
T |
A |
10: 62,937,454 (GRCm38) |
V156E |
possibly damaging |
Het |
| Slc28a3 |
A |
T |
13: 58,610,804 (GRCm38) |
S2T |
probably benign |
Het |
| Srd5a3 |
G |
A |
5: 76,149,866 (GRCm38) |
V48I |
probably benign |
Het |
| Srebf1 |
A |
C |
11: 60,200,526 (GRCm38) |
H1025Q |
probably damaging |
Het |
| Stard9 |
A |
G |
2: 120,697,191 (GRCm38) |
K1310E |
probably benign |
Het |
| Swt1 |
A |
G |
1: 151,370,630 (GRCm38) |
V848A |
possibly damaging |
Het |
| Tanc2 |
A |
T |
11: 105,840,699 (GRCm38) |
T434S |
possibly damaging |
Het |
| Tcf20 |
G |
A |
15: 82,854,682 (GRCm38) |
T856I |
probably benign |
Het |
| Tcf7l2 |
T |
C |
19: 55,894,733 (GRCm38) |
|
probably null |
Het |
| Trim45 |
A |
G |
3: 100,931,879 (GRCm38) |
|
probably benign |
Het |
| Tsen2 |
T |
A |
6: 115,547,972 (GRCm38) |
M44K |
possibly damaging |
Het |
| Ttc21a |
T |
A |
9: 119,958,073 (GRCm38) |
C715* |
probably null |
Het |
| Vmn2r102 |
G |
A |
17: 19,694,194 (GRCm38) |
V674I |
probably damaging |
Het |
| Zfp87 |
A |
G |
13: 67,517,054 (GRCm38) |
S430P |
probably damaging |
Het |
|
| Other mutations in Copa |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00848:Copa
|
APN |
1 |
172,110,688 (GRCm38) |
missense |
possibly damaging |
0.87 |
|
IGL01360:Copa
|
APN |
1 |
172,087,588 (GRCm38) |
splice site |
probably null |
|
|
IGL01434:Copa
|
APN |
1 |
172,119,561 (GRCm38) |
missense |
probably benign |
0.00 |
|
IGL01744:Copa
|
APN |
1 |
172,113,189 (GRCm38) |
missense |
probably benign |
0.01 |
|
IGL01837:Copa
|
APN |
1 |
172,118,852 (GRCm38) |
missense |
probably benign |
0.01 |
|
IGL01988:Copa
|
APN |
1 |
172,118,264 (GRCm38) |
missense |
probably benign |
0.09 |
|
IGL02059:Copa
|
APN |
1 |
172,099,753 (GRCm38) |
missense |
probably damaging |
0.96 |
|
IGL02123:Copa
|
APN |
1 |
172,112,128 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02731:Copa
|
APN |
1 |
172,102,218 (GRCm38) |
missense |
possibly damaging |
0.77 |
|
IGL03114:Copa
|
APN |
1 |
172,119,268 (GRCm38) |
nonsense |
probably null |
|
|
P0027:Copa
|
UTSW |
1 |
172,111,948 (GRCm38) |
missense |
possibly damaging |
0.87 |
|
PIT4434001:Copa
|
UTSW |
1 |
172,106,175 (GRCm38) |
missense |
probably benign |
0.00 |
|
R0233:Copa
|
UTSW |
1 |
172,087,667 (GRCm38) |
critical splice donor site |
probably null |
|
|
R0465:Copa
|
UTSW |
1 |
172,118,305 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0547:Copa
|
UTSW |
1 |
172,121,687 (GRCm38) |
splice site |
probably benign |
|
|
R0568:Copa
|
UTSW |
1 |
172,112,137 (GRCm38) |
missense |
possibly damaging |
0.91 |
|
R0628:Copa
|
UTSW |
1 |
172,091,025 (GRCm38) |
splice site |
probably benign |
|
|
R1328:Copa
|
UTSW |
1 |
172,121,691 (GRCm38) |
splice site |
probably benign |
|
|
R1494:Copa
|
UTSW |
1 |
172,104,127 (GRCm38) |
missense |
probably benign |
0.27 |
|
R1728:Copa
|
UTSW |
1 |
172,111,987 (GRCm38) |
missense |
probably benign |
|
|
R1758:Copa
|
UTSW |
1 |
172,104,144 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1784:Copa
|
UTSW |
1 |
172,111,987 (GRCm38) |
missense |
probably benign |
|
|
R1942:Copa
|
UTSW |
1 |
172,111,888 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2054:Copa
|
UTSW |
1 |
172,118,957 (GRCm38) |
nonsense |
probably null |
|
|
R2299:Copa
|
UTSW |
1 |
172,121,725 (GRCm38) |
missense |
probably benign |
0.10 |
|
R2518:Copa
|
UTSW |
1 |
172,119,901 (GRCm38) |
missense |
probably benign |
|
|
R2680:Copa
|
UTSW |
1 |
172,121,404 (GRCm38) |
nonsense |
probably null |
|
|
R3080:Copa
|
UTSW |
1 |
172,113,149 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3160:Copa
|
UTSW |
1 |
172,091,233 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3161:Copa
|
UTSW |
1 |
172,091,233 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3162:Copa
|
UTSW |
1 |
172,091,233 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3162:Copa
|
UTSW |
1 |
172,091,233 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3973:Copa
|
UTSW |
1 |
172,121,245 (GRCm38) |
missense |
probably benign |
0.00 |
|
R3975:Copa
|
UTSW |
1 |
172,121,245 (GRCm38) |
missense |
probably benign |
0.00 |
|
R4031:Copa
|
UTSW |
1 |
172,108,375 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4155:Copa
|
UTSW |
1 |
172,101,425 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4227:Copa
|
UTSW |
1 |
172,118,115 (GRCm38) |
intron |
probably benign |
|
|
R4244:Copa
|
UTSW |
1 |
172,110,718 (GRCm38) |
missense |
probably benign |
0.00 |
|
R4254:Copa
|
UTSW |
1 |
172,102,244 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4291:Copa
|
UTSW |
1 |
172,092,397 (GRCm38) |
intron |
probably benign |
|
|
R4323:Copa
|
UTSW |
1 |
172,119,264 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4402:Copa
|
UTSW |
1 |
172,102,224 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4711:Copa
|
UTSW |
1 |
172,119,988 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4721:Copa
|
UTSW |
1 |
172,104,274 (GRCm38) |
splice site |
probably benign |
|
|
R4773:Copa
|
UTSW |
1 |
172,105,220 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4794:Copa
|
UTSW |
1 |
172,119,321 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4887:Copa
|
UTSW |
1 |
172,092,276 (GRCm38) |
missense |
probably benign |
0.39 |
|
R4953:Copa
|
UTSW |
1 |
172,082,886 (GRCm38) |
unclassified |
probably benign |
|
|
R5139:Copa
|
UTSW |
1 |
172,121,329 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R5152:Copa
|
UTSW |
1 |
172,118,061 (GRCm38) |
missense |
probably benign |
0.34 |
|
R5297:Copa
|
UTSW |
1 |
172,113,108 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5586:Copa
|
UTSW |
1 |
172,105,222 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5698:Copa
|
UTSW |
1 |
172,118,944 (GRCm38) |
nonsense |
probably null |
|
|
R6283:Copa
|
UTSW |
1 |
172,118,848 (GRCm38) |
missense |
possibly damaging |
0.79 |
|
R6921:Copa
|
UTSW |
1 |
172,111,924 (GRCm38) |
missense |
possibly damaging |
0.63 |
|
R6934:Copa
|
UTSW |
1 |
172,110,686 (GRCm38) |
missense |
possibly damaging |
0.64 |
|
R7194:Copa
|
UTSW |
1 |
172,119,944 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R7348:Copa
|
UTSW |
1 |
172,102,223 (GRCm38) |
missense |
possibly damaging |
0.96 |
|
R7710:Copa
|
UTSW |
1 |
172,109,844 (GRCm38) |
missense |
possibly damaging |
0.50 |
|
R7745:Copa
|
UTSW |
1 |
172,111,942 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7893:Copa
|
UTSW |
1 |
172,119,565 (GRCm38) |
nonsense |
probably null |
|
|
R8168:Copa
|
UTSW |
1 |
172,099,672 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8273:Copa
|
UTSW |
1 |
172,118,979 (GRCm38) |
critical splice donor site |
probably null |
|
|
R8704:Copa
|
UTSW |
1 |
172,104,126 (GRCm38) |
missense |
probably benign |
0.01 |
|
R8754:Copa
|
UTSW |
1 |
172,108,359 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8757:Copa
|
UTSW |
1 |
172,119,514 (GRCm38) |
missense |
probably benign |
0.04 |
|
R8759:Copa
|
UTSW |
1 |
172,119,514 (GRCm38) |
missense |
probably benign |
0.04 |
|
R8885:Copa
|
UTSW |
1 |
172,097,745 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8891:Copa
|
UTSW |
1 |
172,119,251 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8927:Copa
|
UTSW |
1 |
172,104,170 (GRCm38) |
missense |
probably null |
0.03 |
|
R8928:Copa
|
UTSW |
1 |
172,104,170 (GRCm38) |
missense |
probably null |
0.03 |
|
R8956:Copa
|
UTSW |
1 |
172,109,913 (GRCm38) |
missense |
possibly damaging |
0.65 |
|
R9063:Copa
|
UTSW |
1 |
172,116,962 (GRCm38) |
missense |
probably benign |
0.00 |
|
R9295:Copa
|
UTSW |
1 |
172,112,256 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R9364:Copa
|
UTSW |
1 |
172,117,264 (GRCm38) |
missense |
probably benign |
0.00 |
|
R9437:Copa
|
UTSW |
1 |
172,104,145 (GRCm38) |
missense |
possibly damaging |
0.93 |
|
R9673:Copa
|
UTSW |
1 |
172,118,081 (GRCm38) |
missense |
probably benign |
0.11 |
|
T0722:Copa
|
UTSW |
1 |
172,111,948 (GRCm38) |
missense |
possibly damaging |
0.87 |
|
Z1177:Copa
|
UTSW |
1 |
172,106,123 (GRCm38) |
frame shift |
probably null |
|
|
| Predicted Primers |
PCR Primer
(F):5'- GGAGGCAGTTCTGTGAAGACTC -3'
(R):5'- TGAGGCGCTCAGAATCCAAG -3'
Sequencing Primer
(F):5'- AATTCTTAGCGCTCAGGACG -3'
(R):5'- GGCGCTCAGAATCCAAGGATATTC -3'
|
| Posted On |
2019-05-13 |
Incidental Mutation