Incidental Mutation 'R7009:Ints1'
| ID |
544896 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Ints1
|
| Ensembl Gene |
ENSMUSG00000029547 |
| Gene Name |
integrator complex subunit 1 |
| Synonyms |
1110015K06Rik |
| MMRRC Submission |
045111-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R7009 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
5 |
| Chromosomal Location |
139751282-139775674 bp(-) (GRCm38) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 139768462 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Threonine to Alanine
at position 652
(T652A)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000143789
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000072607]
[ENSMUST00000196864]
[ENSMUST00000200393]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
|
| SMART Domains |
Protein: ENSMUSP00000072406
Gene: ENSMUSG00000029547
AA Change: T650A
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
16 |
27 |
N/A |
INTRINSIC |
|
low complexity region
|
88 |
102 |
N/A |
INTRINSIC |
|
Pfam:DUF3677
|
379 |
459 |
6.4e-37 |
PFAM |
|
low complexity region
|
854 |
865 |
N/A |
INTRINSIC |
|
low complexity region
|
870 |
876 |
N/A |
INTRINSIC |
|
low complexity region
|
946 |
962 |
N/A |
INTRINSIC |
|
low complexity region
|
965 |
988 |
N/A |
INTRINSIC |
|
low complexity region
|
1034 |
1045 |
N/A |
INTRINSIC |
|
low complexity region
|
1058 |
1069 |
N/A |
INTRINSIC |
|
low complexity region
|
1347 |
1361 |
N/A |
INTRINSIC |
|
low complexity region
|
1405 |
1418 |
N/A |
INTRINSIC |
|
low complexity region
|
1615 |
1624 |
N/A |
INTRINSIC |
|
low complexity region
|
1763 |
1776 |
N/A |
INTRINSIC |
|
low complexity region
|
1840 |
1855 |
N/A |
INTRINSIC |
|
low complexity region
|
2062 |
2076 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000196864
|
| SMART Domains |
Protein: ENSMUSP00000142362
Gene: ENSMUSG00000029547
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
61 |
75 |
N/A |
INTRINSIC |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000200393
AA Change: T652A
PolyPhen 2
Score 0.835 (Sensitivity: 0.84; Specificity: 0.93)
|
| SMART Domains |
Protein: ENSMUSP00000143789
Gene: ENSMUSG00000029547
AA Change: T652A
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
16 |
27 |
N/A |
INTRINSIC |
|
low complexity region
|
88 |
102 |
N/A |
INTRINSIC |
|
Pfam:DUF3677
|
379 |
459 |
6.4e-37 |
PFAM |
|
low complexity region
|
854 |
865 |
N/A |
INTRINSIC |
|
low complexity region
|
870 |
876 |
N/A |
INTRINSIC |
|
low complexity region
|
946 |
962 |
N/A |
INTRINSIC |
|
low complexity region
|
965 |
988 |
N/A |
INTRINSIC |
|
low complexity region
|
1034 |
1045 |
N/A |
INTRINSIC |
|
low complexity region
|
1058 |
1069 |
N/A |
INTRINSIC |
|
low complexity region
|
1347 |
1361 |
N/A |
INTRINSIC |
|
low complexity region
|
1405 |
1418 |
N/A |
INTRINSIC |
|
low complexity region
|
1615 |
1624 |
N/A |
INTRINSIC |
|
low complexity region
|
1763 |
1776 |
N/A |
INTRINSIC |
|
low complexity region
|
1840 |
1855 |
N/A |
INTRINSIC |
|
low complexity region
|
2062 |
2076 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 100.0%
- 10x: 99.8%
- 20x: 99.2%
|
| Validation Efficiency |
99% (82/83) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] INTS1 is a subunit of the Integrator complex, which associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A; MIM 180660) and mediates 3-prime end processing of small nuclear RNAs U1 (RNU1; MIM 180680) and U2 (RNU2; MIM 180690) (Baillat et al., 2005 [PubMed 16239144]).[supplied by OMIM, Mar 2008]
PHENOTYPE: Homozygous mutation of this gene results in embryonic lethality at the blastocyst stage. [provided by MGI curators]
|
| Allele List at MGI |
All alleles(10) : Targeted, knock-out(1) Gene trapped(9) |
| Other mutations in this stock |
Total: 83 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1700007G11Rik |
A |
T |
5: 98,784,520 (GRCm38) |
D193V |
probably damaging |
Het |
| 4921517D22Rik |
G |
T |
13: 59,690,810 (GRCm38) |
D69E |
possibly damaging |
Het |
| Abat |
A |
C |
16: 8,602,367 (GRCm38) |
M177L |
probably benign |
Het |
| Acadvl |
A |
G |
11: 70,014,791 (GRCm38) |
|
probably null |
Het |
| Adam5 |
T |
C |
8: 24,806,438 (GRCm38) |
N331S |
probably benign |
Het |
| Ager |
A |
G |
17: 34,600,736 (GRCm38) |
E372G |
probably damaging |
Het |
| Angpt1 |
T |
A |
15: 42,523,595 (GRCm38) |
Q121L |
possibly damaging |
Het |
| Apoa4 |
A |
T |
9: 46,242,880 (GRCm38) |
I260F |
possibly damaging |
Het |
| Arhgap32 |
A |
T |
9: 32,245,976 (GRCm38) |
I90F |
probably damaging |
Het |
| Arhgap5 |
A |
T |
12: 52,519,639 (GRCm38) |
Q1131L |
probably benign |
Het |
| Bach1 |
G |
A |
16: 87,719,291 (GRCm38) |
R240Q |
probably benign |
Het |
| Cacna2d3 |
A |
T |
14: 28,969,365 (GRCm38) |
M1K |
probably null |
Het |
| Ccdc18 |
G |
A |
5: 108,173,862 (GRCm38) |
|
probably null |
Het |
| Ccdc42 |
T |
C |
11: 68,594,616 (GRCm38) |
F267S |
probably damaging |
Het |
| Cdh23 |
T |
A |
10: 60,337,306 (GRCm38) |
Y1700F |
probably damaging |
Het |
| Cenpe |
A |
T |
3: 135,235,201 (GRCm38) |
S704C |
probably damaging |
Het |
| Cenpe |
G |
A |
3: 135,235,202 (GRCm38) |
S704N |
probably benign |
Het |
| Cfap54 |
A |
T |
10: 92,875,019 (GRCm38) |
S2727T |
unknown |
Het |
| Clu |
T |
A |
14: 65,971,832 (GRCm38) |
V113D |
probably damaging |
Het |
| Cnbd2 |
A |
G |
2: 156,320,034 (GRCm38) |
I98V |
probably benign |
Het |
| Copa |
G |
T |
1: 172,091,000 (GRCm38) |
R97L |
probably damaging |
Het |
| Epb41l1 |
C |
A |
2: 156,534,683 (GRCm38) |
|
probably null |
Het |
| Etnk1 |
T |
A |
6: 143,203,154 (GRCm38) |
|
probably null |
Het |
| Fnip1 |
A |
T |
11: 54,502,935 (GRCm38) |
K732N |
probably damaging |
Het |
| G6pd2 |
A |
G |
5: 61,808,891 (GRCm38) |
E3G |
probably benign |
Het |
| Gal3st2 |
A |
G |
1: 93,873,759 (GRCm38) |
T95A |
probably benign |
Het |
| Gapvd1 |
A |
G |
2: 34,700,817 (GRCm38) |
S948P |
probably damaging |
Het |
| Ggps1 |
A |
T |
13: 14,054,165 (GRCm38) |
Y8* |
probably null |
Het |
| Gria2 |
T |
C |
3: 80,706,972 (GRCm38) |
E587G |
probably damaging |
Het |
| Hpse |
T |
C |
5: 100,692,279 (GRCm38) |
E324G |
probably benign |
Het |
| Il16 |
G |
A |
7: 83,646,388 (GRCm38) |
T493I |
probably benign |
Het |
| Ism1 |
A |
G |
2: 139,757,279 (GRCm38) |
I391V |
probably damaging |
Het |
| Katnb1 |
A |
G |
8: 95,098,384 (GRCm38) |
D598G |
probably damaging |
Het |
| Kif5c |
A |
G |
2: 49,757,429 (GRCm38) |
S880G |
probably benign |
Het |
| Klra8 |
T |
C |
6: 130,125,184 (GRCm38) |
N96S |
probably benign |
Het |
| Krt79 |
T |
A |
15: 101,931,441 (GRCm38) |
D373V |
probably damaging |
Het |
| Lamtor4 |
G |
A |
5: 138,259,112 (GRCm38) |
R92Q |
probably benign |
Het |
| Lce1d |
C |
A |
3: 92,686,046 (GRCm38) |
C20F |
unknown |
Het |
| Limk1 |
T |
C |
5: 134,672,699 (GRCm38) |
T117A |
probably benign |
Het |
| Medag |
A |
T |
5: 149,427,243 (GRCm38) |
K61M |
probably benign |
Het |
| Mkrn3 |
T |
C |
7: 62,419,618 (GRCm38) |
M142V |
probably benign |
Het |
| Mob3c |
G |
A |
4: 115,831,582 (GRCm38) |
R104H |
probably benign |
Het |
| Morc1 |
G |
T |
16: 48,627,070 (GRCm38) |
R903L |
possibly damaging |
Het |
| Myh6 |
T |
C |
14: 54,952,292 (GRCm38) |
E1099G |
probably damaging |
Het |
| Nphp3 |
T |
G |
9: 104,016,116 (GRCm38) |
C434G |
probably null |
Het |
| Npr3 |
C |
T |
15: 11,905,248 (GRCm38) |
C131Y |
probably damaging |
Het |
| Oacyl |
C |
A |
18: 65,722,538 (GRCm38) |
Y112* |
probably null |
Het |
| Oprl1 |
A |
G |
2: 181,718,381 (GRCm38) |
T77A |
probably damaging |
Het |
| Osgep |
A |
G |
14: 50,924,708 (GRCm38) |
V24A |
probably damaging |
Het |
| Otx2 |
T |
A |
14: 48,658,797 (GRCm38) |
K260M |
probably damaging |
Het |
| Pdcd11 |
T |
C |
19: 47,113,142 (GRCm38) |
L922P |
probably benign |
Het |
| Phldb1 |
A |
G |
9: 44,694,408 (GRCm38) |
V375A |
probably damaging |
Het |
| Pip5k1b |
C |
T |
19: 24,359,935 (GRCm38) |
|
probably null |
Het |
| Psmd3 |
G |
A |
11: 98,682,766 (GRCm38) |
D13N |
probably benign |
Het |
| Ptprc |
G |
A |
1: 138,064,553 (GRCm38) |
H1140Y |
probably damaging |
Het |
| Ranbp3l |
A |
T |
15: 9,062,984 (GRCm38) |
H291L |
probably damaging |
Het |
| Rasa4 |
T |
A |
5: 136,101,363 (GRCm38) |
D324E |
probably damaging |
Het |
| Rilpl1 |
T |
A |
5: 124,503,692 (GRCm38) |
|
silent |
Het |
| Rin2 |
A |
C |
2: 145,883,475 (GRCm38) |
D794A |
probably damaging |
Het |
| Ripk1 |
A |
G |
13: 34,030,062 (GRCm38) |
I522M |
probably damaging |
Het |
| Rnf31 |
T |
C |
14: 55,592,551 (GRCm38) |
Y143H |
probably benign |
Het |
| Rp1 |
T |
G |
1: 4,042,068 (GRCm38) |
I1187L |
unknown |
Het |
| Rps6ka5 |
G |
A |
12: 100,619,537 (GRCm38) |
H166Y |
probably damaging |
Het |
| Rrm1 |
T |
C |
7: 102,460,334 (GRCm38) |
V455A |
probably damaging |
Het |
| Runx2 |
G |
A |
17: 44,814,192 (GRCm38) |
P80L |
probably damaging |
Het |
| Scn5a |
T |
G |
9: 119,485,930 (GRCm38) |
E1904A |
probably damaging |
Het |
| Sec16a |
G |
T |
2: 26,436,002 (GRCm38) |
S240* |
probably null |
Het |
| Slc22a8 |
C |
T |
19: 8,605,417 (GRCm38) |
T154I |
probably benign |
Het |
| Slc25a16 |
T |
A |
10: 62,937,454 (GRCm38) |
V156E |
possibly damaging |
Het |
| Slc28a3 |
A |
T |
13: 58,610,804 (GRCm38) |
S2T |
probably benign |
Het |
| Srd5a3 |
G |
A |
5: 76,149,866 (GRCm38) |
V48I |
probably benign |
Het |
| Srebf1 |
A |
C |
11: 60,200,526 (GRCm38) |
H1025Q |
probably damaging |
Het |
| Stard9 |
A |
G |
2: 120,697,191 (GRCm38) |
K1310E |
probably benign |
Het |
| Swt1 |
A |
G |
1: 151,370,630 (GRCm38) |
V848A |
possibly damaging |
Het |
| Tanc2 |
A |
T |
11: 105,840,699 (GRCm38) |
T434S |
possibly damaging |
Het |
| Tcf20 |
G |
A |
15: 82,854,682 (GRCm38) |
T856I |
probably benign |
Het |
| Tcf7l2 |
T |
C |
19: 55,894,733 (GRCm38) |
|
probably null |
Het |
| Tmem246 |
A |
T |
4: 49,586,325 (GRCm38) |
M281K |
probably benign |
Het |
| Trim45 |
A |
G |
3: 100,931,879 (GRCm38) |
|
probably benign |
Het |
| Tsen2 |
T |
A |
6: 115,547,972 (GRCm38) |
M44K |
possibly damaging |
Het |
| Ttc21a |
T |
A |
9: 119,958,073 (GRCm38) |
C715* |
probably null |
Het |
| Vmn2r102 |
G |
A |
17: 19,694,194 (GRCm38) |
V674I |
probably damaging |
Het |
| Zfp87 |
A |
G |
13: 67,517,054 (GRCm38) |
S430P |
probably damaging |
Het |
|
| Other mutations in Ints1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01116:Ints1
|
APN |
5 |
139,771,682 (GRCm38) |
missense |
probably damaging |
0.99 |
|
IGL01329:Ints1
|
APN |
5 |
139,767,503 (GRCm38) |
splice site |
probably benign |
|
|
IGL01414:Ints1
|
APN |
5 |
139,758,498 (GRCm38) |
missense |
probably benign |
|
|
IGL01612:Ints1
|
APN |
5 |
139,756,292 (GRCm38) |
missense |
probably benign |
0.17 |
|
IGL01726:Ints1
|
APN |
5 |
139,768,411 (GRCm38) |
splice site |
probably benign |
|
|
IGL01958:Ints1
|
APN |
5 |
139,760,088 (GRCm38) |
missense |
possibly damaging |
0.94 |
|
IGL02122:Ints1
|
APN |
5 |
139,765,150 (GRCm38) |
nonsense |
probably null |
|
|
IGL02149:Ints1
|
APN |
5 |
139,751,960 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02349:Ints1
|
APN |
5 |
139,768,468 (GRCm38) |
missense |
probably damaging |
0.96 |
|
IGL02557:Ints1
|
APN |
5 |
139,771,637 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02814:Ints1
|
APN |
5 |
139,772,391 (GRCm38) |
missense |
possibly damaging |
0.80 |
|
IGL02815:Ints1
|
APN |
5 |
139,755,282 (GRCm38) |
missense |
probably damaging |
0.96 |
|
IGL02825:Ints1
|
APN |
5 |
139,764,739 (GRCm38) |
missense |
probably benign |
0.32 |
|
IGL03000:Ints1
|
APN |
5 |
139,766,506 (GRCm38) |
missense |
probably benign |
0.01 |
|
IGL03164:Ints1
|
APN |
5 |
139,752,735 (GRCm38) |
missense |
probably damaging |
0.99 |
|
forgiving
|
UTSW |
5 |
139,767,828 (GRCm38) |
missense |
probably damaging |
0.99 |
|
restrained
|
UTSW |
5 |
139,767,726 (GRCm38) |
missense |
possibly damaging |
0.68 |
|
A9681:Ints1
|
UTSW |
5 |
139,770,139 (GRCm38) |
missense |
possibly damaging |
0.56 |
|
R0113:Ints1
|
UTSW |
5 |
139,765,213 (GRCm38) |
missense |
|
|
|
R0193:Ints1
|
UTSW |
5 |
139,751,730 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0372:Ints1
|
UTSW |
5 |
139,772,438 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1129:Ints1
|
UTSW |
5 |
139,758,471 (GRCm38) |
missense |
probably benign |
0.00 |
|
R1290:Ints1
|
UTSW |
5 |
139,771,410 (GRCm38) |
nonsense |
probably null |
|
|
R1313:Ints1
|
UTSW |
5 |
139,762,906 (GRCm38) |
missense |
probably benign |
|
|
R1313:Ints1
|
UTSW |
5 |
139,762,906 (GRCm38) |
missense |
probably benign |
|
|
R1691:Ints1
|
UTSW |
5 |
139,768,932 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1708:Ints1
|
UTSW |
5 |
139,762,839 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1791:Ints1
|
UTSW |
5 |
139,774,522 (GRCm38) |
missense |
probably benign |
0.04 |
|
R2066:Ints1
|
UTSW |
5 |
139,767,496 (GRCm38) |
missense |
probably benign |
0.14 |
|
R2102:Ints1
|
UTSW |
5 |
139,755,999 (GRCm38) |
missense |
possibly damaging |
0.50 |
|
R2108:Ints1
|
UTSW |
5 |
139,767,750 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2238:Ints1
|
UTSW |
5 |
139,765,200 (GRCm38) |
missense |
possibly damaging |
0.95 |
|
R2426:Ints1
|
UTSW |
5 |
139,771,814 (GRCm38) |
critical splice donor site |
probably null |
|
|
R2913:Ints1
|
UTSW |
5 |
139,757,913 (GRCm38) |
missense |
possibly damaging |
0.91 |
|
R3896:Ints1
|
UTSW |
5 |
139,757,644 (GRCm38) |
nonsense |
probably null |
|
|
R4608:Ints1
|
UTSW |
5 |
139,759,844 (GRCm38) |
missense |
probably benign |
0.13 |
|
R4658:Ints1
|
UTSW |
5 |
139,774,299 (GRCm38) |
missense |
possibly damaging |
0.88 |
|
R4797:Ints1
|
UTSW |
5 |
139,771,876 (GRCm38) |
missense |
possibly damaging |
0.85 |
|
R4887:Ints1
|
UTSW |
5 |
139,771,156 (GRCm38) |
missense |
possibly damaging |
0.66 |
|
R4944:Ints1
|
UTSW |
5 |
139,758,092 (GRCm38) |
splice site |
probably null |
|
|
R4956:Ints1
|
UTSW |
5 |
139,757,130 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4976:Ints1
|
UTSW |
5 |
139,752,811 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5283:Ints1
|
UTSW |
5 |
139,764,382 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5354:Ints1
|
UTSW |
5 |
139,766,428 (GRCm38) |
critical splice donor site |
probably null |
|
|
R5496:Ints1
|
UTSW |
5 |
139,755,198 (GRCm38) |
missense |
probably benign |
0.07 |
|
R5517:Ints1
|
UTSW |
5 |
139,752,787 (GRCm38) |
missense |
possibly damaging |
0.86 |
|
R5696:Ints1
|
UTSW |
5 |
139,754,989 (GRCm38) |
missense |
probably benign |
0.00 |
|
R5766:Ints1
|
UTSW |
5 |
139,772,145 (GRCm38) |
missense |
probably benign |
0.33 |
|
R6359:Ints1
|
UTSW |
5 |
139,756,217 (GRCm38) |
missense |
probably benign |
0.09 |
|
R6753:Ints1
|
UTSW |
5 |
139,765,175 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6892:Ints1
|
UTSW |
5 |
139,767,828 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R7047:Ints1
|
UTSW |
5 |
139,758,471 (GRCm38) |
nonsense |
probably null |
|
|
R7216:Ints1
|
UTSW |
5 |
139,768,984 (GRCm38) |
missense |
possibly damaging |
0.91 |
|
R7220:Ints1
|
UTSW |
5 |
139,762,073 (GRCm38) |
missense |
possibly damaging |
0.91 |
|
R7263:Ints1
|
UTSW |
5 |
139,764,079 (GRCm38) |
missense |
possibly damaging |
0.50 |
|
R7291:Ints1
|
UTSW |
5 |
139,765,074 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7319:Ints1
|
UTSW |
5 |
139,760,765 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7411:Ints1
|
UTSW |
5 |
139,764,260 (GRCm38) |
missense |
possibly damaging |
0.54 |
|
R7497:Ints1
|
UTSW |
5 |
139,768,976 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R7529:Ints1
|
UTSW |
5 |
139,767,726 (GRCm38) |
missense |
possibly damaging |
0.68 |
|
R7710:Ints1
|
UTSW |
5 |
139,771,085 (GRCm38) |
missense |
probably benign |
0.17 |
|
R7816:Ints1
|
UTSW |
5 |
139,771,379 (GRCm38) |
missense |
possibly damaging |
0.90 |
|
R7819:Ints1
|
UTSW |
5 |
139,760,767 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7992:Ints1
|
UTSW |
5 |
139,756,527 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8260:Ints1
|
UTSW |
5 |
139,765,213 (GRCm38) |
missense |
|
|
|
R8265:Ints1
|
UTSW |
5 |
139,772,164 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8782:Ints1
|
UTSW |
5 |
139,759,197 (GRCm38) |
missense |
probably benign |
0.28 |
|
R9016:Ints1
|
UTSW |
5 |
139,758,571 (GRCm38) |
missense |
probably benign |
|
|
R9053:Ints1
|
UTSW |
5 |
139,762,067 (GRCm38) |
missense |
possibly damaging |
0.55 |
|
R9056:Ints1
|
UTSW |
5 |
139,774,286 (GRCm38) |
critical splice donor site |
probably null |
|
|
R9080:Ints1
|
UTSW |
5 |
139,753,545 (GRCm38) |
missense |
probably benign |
0.00 |
|
R9086:Ints1
|
UTSW |
5 |
139,758,192 (GRCm38) |
missense |
probably benign |
|
|
R9122:Ints1
|
UTSW |
5 |
139,760,175 (GRCm38) |
missense |
possibly damaging |
0.83 |
|
R9134:Ints1
|
UTSW |
5 |
139,757,596 (GRCm38) |
missense |
probably benign |
|
|
R9135:Ints1
|
UTSW |
5 |
139,751,946 (GRCm38) |
missense |
possibly damaging |
0.49 |
|
R9169:Ints1
|
UTSW |
5 |
139,762,831 (GRCm38) |
missense |
probably benign |
|
|
R9280:Ints1
|
UTSW |
5 |
139,764,714 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9458:Ints1
|
UTSW |
5 |
139,757,652 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9666:Ints1
|
UTSW |
5 |
139,762,462 (GRCm38) |
missense |
probably benign |
0.00 |
|
Z1177:Ints1
|
UTSW |
5 |
139,771,638 (GRCm38) |
missense |
possibly damaging |
0.64 |
|
| Predicted Primers |
PCR Primer
(F):5'- CAGCAGTGTCTAGCAGCTAG -3'
(R):5'- CTCTCTTGGTCACTAGTGGC -3'
Sequencing Primer
(F):5'- TGGAGAGGCCATGTCTCAG -3'
(R):5'- CTTTTGCCCAAATGGTCC -3'
|
| Posted On |
2019-05-13 |
Incidental Mutation