Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL00593:Zfp786'

5452

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Zfp786

Ensembl Gene

ENSMUSG00000051499

Gene Name

zinc finger protein 786

Synonyms

A730012O14Rik

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.068) question?

Stock #

IGL00593

Quality Score

Status

Chromosome

Chromosomal Location

47796200-47807801 bp(-) (GRCm39)

Type of Mutation

makesense

DNA Base Change (assembly)

A to T at 47796605 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Stop codon to Arginine at position 778 (*778R)

Ref Sequence

ENSEMBL: ENSMUSP00000057495 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000058844]

AlphaFold

Q8BV42

Predicted Effect

probably null
Transcript: ENSMUST00000058844
AA Change: *778R

SMART Domains

Protein: ENSMUSP00000057495
Gene: ENSMUSG00000051499
AA Change: *778R

Domain	Start	End	E-Value	Type
KRAB	9	69	2.6e-22	SMART
low complexity region	156	164	N/A	INTRINSIC
ZnF_C2H2	240	262	5.34e-1	SMART
ZnF_C2H2	268	295	1.41e2	SMART
ZnF_C2H2	420	440	1.21e2	SMART
ZnF_C2H2	448	470	3.52e-1	SMART
ZnF_C2H2	476	498	1.89e-1	SMART
ZnF_C2H2	504	526	1.69e-3	SMART
ZnF_C2H2	532	554	5.59e-4	SMART
ZnF_C2H2	560	582	4.79e-3	SMART
ZnF_C2H2	588	610	3.69e-4	SMART
ZnF_C2H2	616	638	3.63e-3	SMART
ZnF_C2H2	644	665	5.92e0	SMART
ZnF_C2H2	671	693	2.57e-3	SMART
ZnF_C2H2	699	721	1.38e-3	SMART
ZnF_C2H2	727	749	1.45e-2	SMART

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000080603

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000143979

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 15 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Agtr2	A	T	X: 21,352,719 (GRCm39)	K118*	probably null	Het
Akap14	A	T	X: 36,414,484 (GRCm39)	H525Q	possibly damaging	Het
Crb1	T	C	1: 139,250,983 (GRCm39)	I323V	probably benign	Het
H60b	T	C	10: 22,162,962 (GRCm39)	I179T	possibly damaging	Het
Krt34	A	G	11: 99,929,520 (GRCm39)		probably benign	Het
Mroh9	T	C	1: 162,873,350 (GRCm39)	N541D	possibly damaging	Het
Plxnb1	A	T	9: 108,942,936 (GRCm39)	I1841F	probably benign	Het
Ppp4r3b	A	G	11: 29,147,205 (GRCm39)	D3G	possibly damaging	Het
Rp1	T	C	1: 4,415,626 (GRCm39)	T1829A	possibly damaging	Het
Ssx2ip	T	C	3: 146,142,307 (GRCm39)	F468L	probably damaging	Het
Togaram1	A	G	12: 65,053,173 (GRCm39)	E1301G	probably damaging	Het
Tpd52l2	A	T	2: 181,141,689 (GRCm39)	D24V	probably damaging	Het
Trmo	A	G	4: 46,382,490 (GRCm39)	V209A	probably benign	Het
Zfp141	A	T	7: 42,124,731 (GRCm39)	C580*	probably null	Het
Zfp422	C	A	6: 116,603,919 (GRCm39)	A27S	probably benign	Het

Other mutations in Zfp786

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL02442:Zfp786	APN	6	47,798,301 (GRCm39)	missense	probably benign	0.00
IGL02674:Zfp786	APN	6	47,797,427 (GRCm39)	missense	probably benign	0.22
IGL02814:Zfp786	APN	6	47,796,775 (GRCm39)	missense	probably damaging	1.00
IGL03072:Zfp786	APN	6	47,798,177 (GRCm39)	missense	probably benign	0.01
IGL03294:Zfp786	APN	6	47,798,258 (GRCm39)	nonsense	probably null
IGL03393:Zfp786	APN	6	47,798,458 (GRCm39)	missense	possibly damaging	0.88
3-1:Zfp786	UTSW	6	47,797,379 (GRCm39)	missense	probably damaging	1.00
PIT4581001:Zfp786	UTSW	6	47,796,756 (GRCm39)	missense	probably damaging	1.00
R1071:Zfp786	UTSW	6	47,798,239 (GRCm39)	missense	possibly damaging	0.91
R1426:Zfp786	UTSW	6	47,802,013 (GRCm39)	missense	probably benign	0.17
R1976:Zfp786	UTSW	6	47,796,691 (GRCm39)	missense	probably damaging	1.00
R2114:Zfp786	UTSW	6	47,803,931 (GRCm39)	missense	probably damaging	1.00
R2115:Zfp786	UTSW	6	47,803,931 (GRCm39)	missense	probably damaging	1.00
R2117:Zfp786	UTSW	6	47,803,931 (GRCm39)	missense	probably damaging	1.00
R2176:Zfp786	UTSW	6	47,797,905 (GRCm39)	missense	possibly damaging	0.65
R2304:Zfp786	UTSW	6	47,797,633 (GRCm39)	missense	probably damaging	1.00
R3110:Zfp786	UTSW	6	47,797,160 (GRCm39)	missense	probably damaging	1.00
R3112:Zfp786	UTSW	6	47,797,160 (GRCm39)	missense	probably damaging	1.00
R3623:Zfp786	UTSW	6	47,798,357 (GRCm39)	missense	probably benign	0.00
R4654:Zfp786	UTSW	6	47,797,868 (GRCm39)	missense	probably benign	0.01
R4741:Zfp786	UTSW	6	47,797,625 (GRCm39)	missense	probably damaging	1.00
R4927:Zfp786	UTSW	6	47,797,087 (GRCm39)	missense	probably benign	0.43
R4936:Zfp786	UTSW	6	47,798,202 (GRCm39)	nonsense	probably null
R5084:Zfp786	UTSW	6	47,796,953 (GRCm39)	missense	probably benign	0.00
R5445:Zfp786	UTSW	6	47,796,619 (GRCm39)	missense	probably damaging	1.00
R6662:Zfp786	UTSW	6	47,803,920 (GRCm39)	missense	probably damaging	1.00
R7290:Zfp786	UTSW	6	47,796,929 (GRCm39)	missense	probably damaging	1.00
R7561:Zfp786	UTSW	6	47,796,667 (GRCm39)	missense	probably benign	0.02
R8038:Zfp786	UTSW	6	47,798,188 (GRCm39)	missense	probably benign	0.01
R8090:Zfp786	UTSW	6	47,796,943 (GRCm39)	missense	probably damaging	1.00
R8250:Zfp786	UTSW	6	47,797,729 (GRCm39)	missense	possibly damaging	0.85
R8438:Zfp786	UTSW	6	47,796,934 (GRCm39)	missense	probably damaging	1.00
R8516:Zfp786	UTSW	6	47,797,477 (GRCm39)	missense	probably damaging	1.00
R8868:Zfp786	UTSW	6	47,802,015 (GRCm39)	missense	probably damaging	0.99
R9596:Zfp786	UTSW	6	47,797,406 (GRCm39)	nonsense	probably null
R9788:Zfp786	UTSW	6	47,797,816 (GRCm39)	missense	probably benign	0.00

Posted On

2012-04-20