Incidental Mutation 'R7017:Tanc2'
| ID |
545394 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Tanc2
|
| Ensembl Gene |
ENSMUSG00000053580 |
| Gene Name |
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 |
| Synonyms |
5730590C14Rik, 3526402J09Rik |
| MMRRC Submission |
045118-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R7017 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
11 |
| Chromosomal Location |
105480812-105820130 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 105813934 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Isoleucine to Valine
at position 1793
(I1793V)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000097904
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000100330]
|
| AlphaFold |
A2A690 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000089485
|
| SMART Domains |
Protein: ENSMUSP00000086912
Gene: ENSMUSG00000053580
| Domain | Start | End | E-Value | Type |
|---|
|
ANK
|
35 |
63 |
1.16e3 |
SMART |
|
ANK
|
78 |
107 |
3.31e-1 |
SMART |
|
ANK
|
111 |
140 |
7.71e-2 |
SMART |
|
ANK
|
144 |
173 |
6.12e-5 |
SMART |
|
ANK
|
177 |
206 |
8.99e-3 |
SMART |
|
ANK
|
210 |
239 |
5.71e-5 |
SMART |
|
ANK
|
243 |
272 |
2.11e2 |
SMART |
|
Blast:TPR
|
289 |
322 |
3e-14 |
BLAST |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000100330
AA Change: I1793V
PolyPhen 2
Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
|
| SMART Domains |
Protein: ENSMUSP00000097904
Gene: ENSMUSG00000053580
AA Change: I1793V
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
32 |
50 |
N/A |
INTRINSIC |
|
low complexity region
|
129 |
152 |
N/A |
INTRINSIC |
|
low complexity region
|
362 |
375 |
N/A |
INTRINSIC |
|
low complexity region
|
436 |
447 |
N/A |
INTRINSIC |
|
low complexity region
|
823 |
834 |
N/A |
INTRINSIC |
|
ANK
|
846 |
878 |
2.08e3 |
SMART |
|
ANK
|
882 |
913 |
2.97e2 |
SMART |
|
ANK
|
917 |
946 |
5.75e-1 |
SMART |
|
ANK
|
950 |
979 |
8.62e1 |
SMART |
|
ANK
|
990 |
1018 |
1.16e3 |
SMART |
|
ANK
|
1033 |
1062 |
3.31e-1 |
SMART |
|
ANK
|
1066 |
1095 |
7.71e-2 |
SMART |
|
ANK
|
1099 |
1128 |
6.12e-5 |
SMART |
|
ANK
|
1132 |
1161 |
8.99e-3 |
SMART |
|
ANK
|
1165 |
1194 |
5.71e-5 |
SMART |
|
ANK
|
1198 |
1227 |
2.11e2 |
SMART |
|
TPR
|
1244 |
1277 |
3.89e1 |
SMART |
|
TPR
|
1291 |
1324 |
3.61e-2 |
SMART |
|
TPR
|
1325 |
1358 |
2.82e-4 |
SMART |
|
low complexity region
|
1369 |
1406 |
N/A |
INTRINSIC |
|
low complexity region
|
1533 |
1539 |
N/A |
INTRINSIC |
|
low complexity region
|
1787 |
1802 |
N/A |
INTRINSIC |
|
| Predicted Effect |
|
| SMART Domains |
Protein: ENSMUSP00000123674
Gene: ENSMUSG00000053580
AA Change: I935V
| Domain | Start | End | E-Value | Type |
|---|
|
ANK
|
15 |
46 |
2.97e2 |
SMART |
|
ANK
|
50 |
79 |
5.75e-1 |
SMART |
|
ANK
|
83 |
112 |
8.62e1 |
SMART |
|
ANK
|
123 |
151 |
1.16e3 |
SMART |
|
ANK
|
166 |
195 |
3.31e-1 |
SMART |
|
ANK
|
199 |
228 |
7.71e-2 |
SMART |
|
ANK
|
232 |
261 |
6.12e-5 |
SMART |
|
ANK
|
265 |
294 |
8.99e-3 |
SMART |
|
ANK
|
298 |
327 |
5.71e-5 |
SMART |
|
ANK
|
331 |
360 |
3.44e1 |
SMART |
|
TPR
|
387 |
420 |
3.89e1 |
SMART |
|
TPR
|
434 |
467 |
3.61e-2 |
SMART |
|
TPR
|
468 |
501 |
2.82e-4 |
SMART |
|
low complexity region
|
512 |
549 |
N/A |
INTRINSIC |
|
low complexity region
|
676 |
682 |
N/A |
INTRINSIC |
|
low complexity region
|
930 |
945 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 100.0%
- 10x: 99.8%
- 20x: 99.5%
|
| Validation Efficiency |
100% (75/75) |
| MGI Phenotype |
PHENOTYPE: Mice homozygous for a gene trap vector die prior to E12. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 76 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 2410137M14Rik |
A |
G |
17: 37,288,926 (GRCm39) |
|
probably benign |
Het |
| Acot3 |
A |
T |
12: 84,100,077 (GRCm39) |
|
probably benign |
Het |
| Add3 |
T |
A |
19: 53,222,284 (GRCm39) |
V297E |
possibly damaging |
Het |
| Arfgap1 |
C |
G |
2: 180,618,097 (GRCm39) |
|
probably null |
Het |
| Cacna1i |
T |
C |
15: 80,264,671 (GRCm39) |
F1500L |
probably damaging |
Het |
| Cacna1s |
T |
C |
1: 136,023,596 (GRCm39) |
I945T |
probably damaging |
Het |
| Ccdc180 |
T |
A |
4: 45,940,934 (GRCm39) |
N1334K |
possibly damaging |
Het |
| Cd5l |
C |
A |
3: 87,273,368 (GRCm39) |
Y112* |
probably null |
Het |
| Cracd |
GAGGCAGCGCGAGGCCGAGAGGCAGGAGGAGGAAGCAAGACAACGCGAGGCCGAGAGGCAGG |
GAGACAACGCGAGGCCGAGAGGCAGG |
5: 77,004,795 (GRCm39) |
|
probably benign |
Het |
| Cyp2d40 |
A |
T |
15: 82,644,234 (GRCm39) |
F297Y |
unknown |
Het |
| Ddx4 |
C |
T |
13: 112,738,022 (GRCm39) |
V546I |
probably damaging |
Het |
| Dgkg |
T |
C |
16: 22,391,463 (GRCm39) |
M332V |
probably benign |
Het |
| Dnah12 |
T |
C |
14: 26,456,835 (GRCm39) |
I867T |
probably benign |
Het |
| Dnah2 |
T |
A |
11: 69,382,373 (GRCm39) |
K1246* |
probably null |
Het |
| Drd2 |
G |
A |
9: 49,312,129 (GRCm39) |
V161I |
probably benign |
Het |
| Dsp |
A |
G |
13: 38,370,683 (GRCm39) |
D862G |
probably benign |
Het |
| Ephx4 |
T |
C |
5: 107,553,980 (GRCm39) |
F10S |
probably damaging |
Het |
| Fabp9 |
C |
A |
3: 10,259,756 (GRCm39) |
A76S |
possibly damaging |
Het |
| Fat4 |
G |
A |
3: 38,945,692 (GRCm39) |
M1528I |
probably benign |
Het |
| Fbxl12 |
A |
G |
9: 20,529,616 (GRCm39) |
S84P |
unknown |
Het |
| Fbxo40 |
T |
C |
16: 36,790,732 (GRCm39) |
D126G |
probably damaging |
Het |
| Fpr1 |
C |
T |
17: 18,097,654 (GRCm39) |
V112I |
probably benign |
Het |
| Frem2 |
T |
C |
3: 53,427,023 (GRCm39) |
N2975S |
probably benign |
Het |
| Gask1a |
T |
C |
9: 121,795,052 (GRCm39) |
|
probably null |
Het |
| Gm7945 |
T |
C |
14: 41,105,610 (GRCm39) |
Y156C |
|
Het |
| Gnpat |
T |
C |
8: 125,590,014 (GRCm39) |
V13A |
probably benign |
Het |
| Gpx5 |
G |
A |
13: 21,475,561 (GRCm39) |
P55L |
probably damaging |
Het |
| Hbp1 |
A |
G |
12: 31,993,852 (GRCm39) |
S59P |
probably damaging |
Het |
| Ighv1-36 |
T |
A |
12: 114,843,533 (GRCm39) |
D109V |
probably damaging |
Het |
| Iqcf5 |
T |
A |
9: 106,392,863 (GRCm39) |
I40N |
possibly damaging |
Het |
| Kcnma1 |
T |
G |
14: 23,544,711 (GRCm39) |
I484L |
possibly damaging |
Het |
| Kera |
A |
T |
10: 97,444,939 (GRCm39) |
R99S |
possibly damaging |
Het |
| Kif3b |
T |
A |
2: 153,171,644 (GRCm39) |
S707R |
possibly damaging |
Het |
| Lilra6 |
G |
T |
7: 3,911,707 (GRCm39) |
T317N |
possibly damaging |
Het |
| Lrrc15 |
C |
T |
16: 30,091,780 (GRCm39) |
E520K |
probably benign |
Het |
| Lrrc34 |
C |
T |
3: 30,699,465 (GRCm39) |
|
probably null |
Het |
| Lvrn |
A |
G |
18: 46,983,745 (GRCm39) |
T163A |
probably benign |
Het |
| Met |
T |
A |
6: 17,491,286 (GRCm39) |
L16* |
probably null |
Het |
| Mpzl2 |
G |
T |
9: 44,958,587 (GRCm39) |
D108Y |
probably benign |
Het |
| Mrgprb2 |
T |
A |
7: 48,202,585 (GRCm39) |
I47F |
probably benign |
Het |
| Muc5ac |
G |
C |
7: 141,363,424 (GRCm39) |
|
probably benign |
Het |
| Mybphl |
T |
A |
3: 108,282,154 (GRCm39) |
V128E |
probably damaging |
Het |
| Nckap5 |
A |
T |
1: 126,030,398 (GRCm39) |
D231E |
probably damaging |
Het |
| Or5g23 |
T |
A |
2: 85,438,673 (GRCm39) |
M194L |
probably benign |
Het |
| Orm1 |
T |
A |
4: 63,263,448 (GRCm39) |
I87K |
probably benign |
Het |
| Pdgfrb |
C |
T |
18: 61,214,076 (GRCm39) |
P954S |
probably benign |
Het |
| Pdzd8 |
G |
T |
19: 59,333,784 (GRCm39) |
S79* |
probably null |
Het |
| Pdzd9 |
T |
A |
7: 120,262,225 (GRCm39) |
H79L |
probably benign |
Het |
| Plcg1 |
A |
T |
2: 160,600,017 (GRCm39) |
I926F |
probably damaging |
Het |
| Plec |
A |
T |
15: 76,057,741 (GRCm39) |
F4078L |
probably damaging |
Het |
| Plek |
G |
A |
11: 17,002,220 (GRCm39) |
|
probably benign |
Het |
| Pogz |
T |
C |
3: 94,761,335 (GRCm39) |
I25T |
probably damaging |
Het |
| Ppfia3 |
A |
T |
7: 45,008,224 (GRCm39) |
D215E |
probably benign |
Het |
| Psg22 |
C |
A |
7: 18,458,366 (GRCm39) |
S352R |
probably benign |
Het |
| Ptchd4 |
A |
G |
17: 42,813,626 (GRCm39) |
Y509C |
probably damaging |
Het |
| Ralgapb |
C |
A |
2: 158,290,257 (GRCm39) |
N389K |
probably benign |
Het |
| Rdh1 |
A |
G |
10: 127,598,906 (GRCm39) |
D129G |
probably benign |
Het |
| Rimbp3 |
A |
G |
16: 17,027,610 (GRCm39) |
T345A |
probably benign |
Het |
| S100a14 |
T |
C |
3: 90,434,602 (GRCm39) |
|
probably null |
Het |
| Scamp1 |
T |
A |
13: 94,361,423 (GRCm39) |
R152S |
probably damaging |
Het |
| Slc30a2 |
G |
A |
4: 134,074,726 (GRCm39) |
R161Q |
probably damaging |
Het |
| Srf |
T |
C |
17: 46,861,830 (GRCm39) |
T383A |
probably benign |
Het |
| St6galnac5 |
T |
C |
3: 152,552,040 (GRCm39) |
M176V |
probably damaging |
Het |
| St8sia1 |
C |
A |
6: 142,813,632 (GRCm39) |
V177F |
probably damaging |
Het |
| Syt12 |
C |
T |
19: 4,510,895 (GRCm39) |
|
probably null |
Het |
| Tas2r123 |
A |
G |
6: 132,824,513 (GRCm39) |
I137V |
probably benign |
Het |
| Tenm2 |
T |
A |
11: 36,062,236 (GRCm39) |
Y543F |
probably damaging |
Het |
| Tent5b |
T |
C |
4: 133,213,545 (GRCm39) |
S139P |
possibly damaging |
Het |
| Tgfbr1 |
T |
C |
4: 47,410,728 (GRCm39) |
I488T |
probably damaging |
Het |
| Tgm1 |
T |
A |
14: 55,942,398 (GRCm39) |
Y651F |
possibly damaging |
Het |
| Thbs3 |
A |
T |
3: 89,131,722 (GRCm39) |
D698V |
probably damaging |
Het |
| Tpra1 |
T |
A |
6: 88,885,294 (GRCm39) |
I82N |
probably damaging |
Het |
| Ubr4 |
T |
A |
4: 139,120,401 (GRCm39) |
D275E |
probably damaging |
Het |
| Vmn2r111 |
T |
C |
17: 22,778,032 (GRCm39) |
N549S |
possibly damaging |
Het |
| Wwp1 |
T |
C |
4: 19,623,124 (GRCm39) |
Y787C |
probably damaging |
Het |
| Znfx1 |
T |
C |
2: 166,890,454 (GRCm39) |
S677G |
probably damaging |
Het |
|
| Other mutations in Tanc2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00501:Tanc2
|
APN |
11 |
105,814,046 (GRCm39) |
missense |
probably benign |
0.28 |
|
IGL00688:Tanc2
|
APN |
11 |
105,689,516 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00709:Tanc2
|
APN |
11 |
105,689,621 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01013:Tanc2
|
APN |
11 |
105,515,891 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL01141:Tanc2
|
APN |
11 |
105,777,300 (GRCm39) |
splice site |
probably benign |
|
|
IGL01386:Tanc2
|
APN |
11 |
105,777,207 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01433:Tanc2
|
APN |
11 |
105,701,348 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
IGL01562:Tanc2
|
APN |
11 |
105,670,895 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01979:Tanc2
|
APN |
11 |
105,667,746 (GRCm39) |
missense |
probably benign |
|
|
IGL02104:Tanc2
|
APN |
11 |
105,670,959 (GRCm39) |
unclassified |
probably benign |
|
|
IGL02434:Tanc2
|
APN |
11 |
105,670,868 (GRCm39) |
missense |
probably benign |
0.14 |
|
IGL02534:Tanc2
|
APN |
11 |
105,725,994 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02568:Tanc2
|
APN |
11 |
105,667,777 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL03279:Tanc2
|
APN |
11 |
105,803,918 (GRCm39) |
splice site |
probably null |
|
|
R0595:Tanc2
|
UTSW |
11 |
105,605,003 (GRCm39) |
splice site |
probably null |
|
|
R1131:Tanc2
|
UTSW |
11 |
105,725,828 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1320:Tanc2
|
UTSW |
11 |
105,777,270 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1487:Tanc2
|
UTSW |
11 |
105,814,460 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1497:Tanc2
|
UTSW |
11 |
105,812,963 (GRCm39) |
missense |
probably benign |
0.21 |
|
R1692:Tanc2
|
UTSW |
11 |
105,748,326 (GRCm39) |
missense |
probably benign |
|
|
R1712:Tanc2
|
UTSW |
11 |
105,790,606 (GRCm39) |
missense |
probably benign |
|
|
R1793:Tanc2
|
UTSW |
11 |
105,515,859 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R1812:Tanc2
|
UTSW |
11 |
105,777,212 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1905:Tanc2
|
UTSW |
11 |
105,813,689 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
R1959:Tanc2
|
UTSW |
11 |
105,801,121 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1962:Tanc2
|
UTSW |
11 |
105,689,558 (GRCm39) |
missense |
probably benign |
0.14 |
|
R2122:Tanc2
|
UTSW |
11 |
105,786,775 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2174:Tanc2
|
UTSW |
11 |
105,801,135 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2341:Tanc2
|
UTSW |
11 |
105,725,877 (GRCm39) |
missense |
probably benign |
0.09 |
|
R2497:Tanc2
|
UTSW |
11 |
105,564,319 (GRCm39) |
critical splice donor site |
probably null |
|
|
R3438:Tanc2
|
UTSW |
11 |
105,748,401 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R3711:Tanc2
|
UTSW |
11 |
105,689,516 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3765:Tanc2
|
UTSW |
11 |
105,805,796 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3890:Tanc2
|
UTSW |
11 |
105,689,504 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4193:Tanc2
|
UTSW |
11 |
105,804,888 (GRCm39) |
intron |
probably benign |
|
|
R4609:Tanc2
|
UTSW |
11 |
105,801,066 (GRCm39) |
missense |
probably benign |
0.24 |
|
R4674:Tanc2
|
UTSW |
11 |
105,758,306 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4928:Tanc2
|
UTSW |
11 |
105,758,588 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5008:Tanc2
|
UTSW |
11 |
105,515,886 (GRCm39) |
start codon destroyed |
probably null |
0.46 |
|
R5010:Tanc2
|
UTSW |
11 |
105,670,918 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5135:Tanc2
|
UTSW |
11 |
105,748,379 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R5385:Tanc2
|
UTSW |
11 |
105,667,672 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5409:Tanc2
|
UTSW |
11 |
105,758,311 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R5419:Tanc2
|
UTSW |
11 |
105,813,709 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5501:Tanc2
|
UTSW |
11 |
105,805,811 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5590:Tanc2
|
UTSW |
11 |
105,814,132 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5651:Tanc2
|
UTSW |
11 |
105,689,526 (GRCm39) |
missense |
probably benign |
0.44 |
|
R5798:Tanc2
|
UTSW |
11 |
105,812,681 (GRCm39) |
small deletion |
probably benign |
|
|
R5876:Tanc2
|
UTSW |
11 |
105,813,439 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R5889:Tanc2
|
UTSW |
11 |
105,812,633 (GRCm39) |
missense |
probably benign |
0.23 |
|
R5958:Tanc2
|
UTSW |
11 |
105,731,451 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5999:Tanc2
|
UTSW |
11 |
105,758,543 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6024:Tanc2
|
UTSW |
11 |
105,814,498 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6024:Tanc2
|
UTSW |
11 |
105,758,543 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6025:Tanc2
|
UTSW |
11 |
105,787,373 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R6025:Tanc2
|
UTSW |
11 |
105,758,543 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6048:Tanc2
|
UTSW |
11 |
105,758,543 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6049:Tanc2
|
UTSW |
11 |
105,758,543 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6185:Tanc2
|
UTSW |
11 |
105,803,865 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6335:Tanc2
|
UTSW |
11 |
105,748,382 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6821:Tanc2
|
UTSW |
11 |
105,777,316 (GRCm39) |
splice site |
probably null |
|
|
R6846:Tanc2
|
UTSW |
11 |
105,689,479 (GRCm39) |
missense |
probably benign |
0.34 |
|
R6857:Tanc2
|
UTSW |
11 |
105,801,114 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R6904:Tanc2
|
UTSW |
11 |
105,726,056 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R7009:Tanc2
|
UTSW |
11 |
105,731,525 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
R7371:Tanc2
|
UTSW |
11 |
105,689,422 (GRCm39) |
missense |
probably benign |
|
|
R7556:Tanc2
|
UTSW |
11 |
105,799,857 (GRCm39) |
missense |
|
|
|
R7630:Tanc2
|
UTSW |
11 |
105,667,734 (GRCm39) |
missense |
probably benign |
0.04 |
|
R7693:Tanc2
|
UTSW |
11 |
105,814,293 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7757:Tanc2
|
UTSW |
11 |
105,667,684 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R7807:Tanc2
|
UTSW |
11 |
105,758,480 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7878:Tanc2
|
UTSW |
11 |
105,804,241 (GRCm39) |
missense |
|
|
|
R7895:Tanc2
|
UTSW |
11 |
105,812,651 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7952:Tanc2
|
UTSW |
11 |
105,787,423 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8099:Tanc2
|
UTSW |
11 |
105,754,833 (GRCm39) |
missense |
probably benign |
0.17 |
|
R8117:Tanc2
|
UTSW |
11 |
105,725,988 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8133:Tanc2
|
UTSW |
11 |
105,814,048 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R8422:Tanc2
|
UTSW |
11 |
105,726,014 (GRCm39) |
missense |
probably benign |
0.10 |
|
R8527:Tanc2
|
UTSW |
11 |
105,807,834 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R8542:Tanc2
|
UTSW |
11 |
105,807,834 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R8834:Tanc2
|
UTSW |
11 |
105,807,845 (GRCm39) |
missense |
|
|
|
R8912:Tanc2
|
UTSW |
11 |
105,758,153 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8927:Tanc2
|
UTSW |
11 |
105,701,331 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8928:Tanc2
|
UTSW |
11 |
105,701,331 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8968:Tanc2
|
UTSW |
11 |
105,758,400 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R9065:Tanc2
|
UTSW |
11 |
105,689,518 (GRCm39) |
nonsense |
probably null |
|
|
R9095:Tanc2
|
UTSW |
11 |
105,758,104 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9108:Tanc2
|
UTSW |
11 |
105,810,580 (GRCm39) |
intron |
probably benign |
|
|
R9131:Tanc2
|
UTSW |
11 |
105,689,603 (GRCm39) |
missense |
probably benign |
|
|
R9294:Tanc2
|
UTSW |
11 |
105,777,284 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9445:Tanc2
|
UTSW |
11 |
105,758,290 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
X0027:Tanc2
|
UTSW |
11 |
105,726,009 (GRCm39) |
missense |
probably benign |
0.26 |
|
| Predicted Primers |
PCR Primer
(F):5'- AAAACTAGATCTGGAGCGTTCCTC -3'
(R):5'- TCCGATTCTGCTGGTGAAGG -3'
Sequencing Primer
(F):5'- AGCGTTCCTCCAGCCAG -3'
(R):5'- TCTATGATCCCCATGAATGGTG -3'
|
| Posted On |
2019-05-13 |
Incidental Mutation