Incidental Mutation 'R7023:Megf6'
| ID |
545751 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Megf6
|
| Ensembl Gene |
ENSMUSG00000057751 |
| Gene Name |
multiple EGF-like-domains 6 |
| Synonyms |
2600001P17Rik, Egfl3 |
| MMRRC Submission |
045124-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R7023 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
4 |
| Chromosomal Location |
154255187-154360170 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 154338602 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Leucine to Proline
at position 467
(L467P)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000030897
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000030897]
[ENSMUST00000152159]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000030897
AA Change: L467P
PolyPhen 2
Score 0.950 (Sensitivity: 0.79; Specificity: 0.95)
|
| SMART Domains |
Protein: ENSMUSP00000030897
Gene: ENSMUSG00000057751
AA Change: L467P
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
28 |
N/A |
INTRINSIC |
|
EGF_CA
|
122 |
162 |
1.54e-6 |
SMART |
|
EGF_CA
|
163 |
203 |
2.08e-12 |
SMART |
|
EGF
|
207 |
245 |
5.4e-2 |
SMART |
|
EGF
|
249 |
286 |
2.39e-3 |
SMART |
|
EGF_CA
|
287 |
327 |
4.96e-10 |
SMART |
|
EGF
|
336 |
373 |
1.64e-1 |
SMART |
|
EGF
|
377 |
413 |
1.99e1 |
SMART |
|
EGF_CA
|
414 |
454 |
7.4e-9 |
SMART |
|
EGF
|
521 |
554 |
4.26e0 |
SMART |
|
EGF_Lam
|
570 |
609 |
1.19e-3 |
SMART |
|
EGF_like
|
613 |
652 |
5.29e-1 |
SMART |
|
EGF
|
642 |
685 |
2.2e1 |
SMART |
|
EGF_Lam
|
656 |
697 |
1.04e-3 |
SMART |
|
EGF
|
687 |
730 |
1.59e1 |
SMART |
|
EGF_like
|
701 |
742 |
2.27e0 |
SMART |
|
EGF_Lam
|
746 |
784 |
1.33e-1 |
SMART |
|
EGF
|
783 |
816 |
2.85e-1 |
SMART |
|
EGF_Lam
|
832 |
871 |
3.88e-3 |
SMART |
|
EGF_Lam
|
875 |
915 |
3.25e-5 |
SMART |
|
EGF
|
914 |
946 |
4.7e-2 |
SMART |
|
EGF_like
|
962 |
1001 |
1.69e-1 |
SMART |
|
EGF
|
1000 |
1032 |
7.02e-1 |
SMART |
|
EGF_Lam
|
1048 |
1087 |
3.1e-2 |
SMART |
|
EGF
|
1077 |
1118 |
7.53e-1 |
SMART |
|
EGF_like
|
1091 |
1130 |
5.59e-1 |
SMART |
|
EGF
|
1129 |
1161 |
5.04e-2 |
SMART |
|
EGF_Lam
|
1177 |
1216 |
2.94e-3 |
SMART |
|
EGF
|
1206 |
1248 |
1.87e1 |
SMART |
|
EGF_Lam
|
1220 |
1260 |
3.1e-2 |
SMART |
|
EGF
|
1259 |
1291 |
1.73e0 |
SMART |
|
EGF
|
1302 |
1334 |
6.55e-1 |
SMART |
|
EGF
|
1345 |
1377 |
4.39e-2 |
SMART |
|
EGF_Lam
|
1393 |
1432 |
7.64e-2 |
SMART |
|
EGF_Lam
|
1436 |
1475 |
2.64e-5 |
SMART |
|
EGF_like
|
1465 |
1506 |
4.2e1 |
SMART |
|
EGF_Lam
|
1479 |
1518 |
1.19e-3 |
SMART |
|
EGF
|
1517 |
1549 |
1.84e1 |
SMART |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000152159
AA Change: L359P
PolyPhen 2
Score 0.907 (Sensitivity: 0.81; Specificity: 0.94)
|
| SMART Domains |
Protein: ENSMUSP00000121641
Gene: ENSMUSG00000057751
AA Change: L359P
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
25 |
N/A |
INTRINSIC |
|
EGF_CA
|
55 |
95 |
2.08e-12 |
SMART |
|
EGF
|
99 |
137 |
5.4e-2 |
SMART |
|
EGF
|
141 |
178 |
2.39e-3 |
SMART |
|
EGF_CA
|
179 |
219 |
4.96e-10 |
SMART |
|
EGF
|
228 |
265 |
1.64e-1 |
SMART |
|
EGF
|
269 |
305 |
1.99e1 |
SMART |
|
EGF_CA
|
306 |
346 |
7.4e-9 |
SMART |
|
EGF
|
413 |
446 |
4.26e0 |
SMART |
|
EGF_Lam
|
462 |
501 |
1.19e-3 |
SMART |
|
EGF_like
|
505 |
544 |
5.29e-1 |
SMART |
|
EGF
|
534 |
577 |
2.2e1 |
SMART |
|
EGF_Lam
|
548 |
589 |
1.04e-3 |
SMART |
|
EGF
|
579 |
622 |
1.59e1 |
SMART |
|
EGF_like
|
593 |
634 |
2.27e0 |
SMART |
|
EGF_Lam
|
638 |
676 |
1.33e-1 |
SMART |
|
EGF
|
675 |
708 |
2.85e-1 |
SMART |
|
EGF_Lam
|
724 |
763 |
3.88e-3 |
SMART |
|
EGF_Lam
|
767 |
807 |
3.25e-5 |
SMART |
|
EGF
|
806 |
838 |
4.7e-2 |
SMART |
|
EGF_Lam
|
854 |
893 |
2.56e-3 |
SMART |
|
EGF
|
892 |
924 |
2.02e-1 |
SMART |
|
EGF
|
935 |
967 |
7.13e-2 |
SMART |
|
EGF
|
978 |
1010 |
1.73e0 |
SMART |
|
EGF
|
1021 |
1053 |
6.55e-1 |
SMART |
|
EGF
|
1064 |
1096 |
4.39e-2 |
SMART |
|
EGF
|
1107 |
1139 |
4.97e-1 |
SMART |
|
EGF
|
1159 |
1191 |
1.84e1 |
SMART |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 100.0%
- 10x: 99.7%
- 20x: 98.9%
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 85 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4833420G17Rik |
A |
G |
13: 119,610,443 (GRCm39) |
H372R |
probably benign |
Het |
| 4933405O20Rik |
T |
C |
7: 50,250,001 (GRCm39) |
I345T |
probably damaging |
Het |
| 4933427D14Rik |
A |
G |
11: 72,069,229 (GRCm39) |
|
probably null |
Het |
| 6430548M08Rik |
T |
C |
8: 120,872,096 (GRCm39) |
V8A |
probably damaging |
Het |
| Adam2 |
A |
T |
14: 66,280,505 (GRCm39) |
D501E |
probably benign |
Het |
| Agbl3 |
T |
C |
6: 34,791,704 (GRCm39) |
V602A |
probably benign |
Het |
| Akap12 |
T |
C |
10: 4,306,895 (GRCm39) |
M1235T |
probably benign |
Het |
| Arid5a |
G |
A |
1: 36,356,631 (GRCm39) |
|
probably benign |
Het |
| Asxl1 |
T |
A |
2: 153,242,469 (GRCm39) |
D1006E |
probably benign |
Het |
| AY074887 |
T |
C |
9: 54,858,149 (GRCm39) |
|
probably benign |
Het |
| Btbd9 |
T |
A |
17: 30,746,546 (GRCm39) |
R93S |
probably benign |
Het |
| Cabp2 |
A |
T |
19: 4,132,658 (GRCm39) |
|
probably null |
Het |
| Cacna1e |
T |
C |
1: 154,601,439 (GRCm39) |
D76G |
probably null |
Het |
| Cd177 |
A |
G |
7: 24,459,187 (GRCm39) |
I74T |
probably benign |
Het |
| Chchd1 |
G |
A |
14: 20,753,310 (GRCm39) |
|
probably benign |
Het |
| Col28a1 |
T |
C |
6: 8,083,763 (GRCm39) |
R565G |
possibly damaging |
Het |
| Cpvl |
T |
A |
6: 53,944,797 (GRCm39) |
I80F |
probably benign |
Het |
| Csgalnact1 |
T |
C |
8: 68,811,081 (GRCm39) |
T530A |
probably benign |
Het |
| Cybrd1 |
A |
G |
2: 70,968,922 (GRCm39) |
D265G |
probably benign |
Het |
| Cyp2c69 |
A |
T |
19: 39,865,986 (GRCm39) |
N202K |
probably benign |
Het |
| D1Pas1 |
A |
G |
1: 186,700,205 (GRCm39) |
N45D |
probably damaging |
Het |
| Dclre1a |
A |
G |
19: 56,528,638 (GRCm39) |
V839A |
probably damaging |
Het |
| Degs1 |
A |
T |
1: 182,106,630 (GRCm39) |
Y210N |
probably damaging |
Het |
| Doc2g |
A |
G |
19: 4,054,778 (GRCm39) |
S220G |
probably benign |
Het |
| Epb41l2 |
T |
A |
10: 25,388,875 (GRCm39) |
L885Q |
probably damaging |
Het |
| Fabp1 |
A |
T |
6: 71,180,069 (GRCm39) |
|
probably null |
Het |
| Fat2 |
G |
A |
11: 55,201,328 (GRCm39) |
S582L |
probably benign |
Het |
| Fcgbpl1 |
T |
A |
7: 27,839,463 (GRCm39) |
C425* |
probably null |
Het |
| Fras1 |
A |
G |
5: 96,857,943 (GRCm39) |
N2079S |
probably benign |
Het |
| Gdf6 |
T |
C |
4: 9,860,210 (GRCm39) |
Y431H |
probably damaging |
Het |
| Gfra1 |
A |
T |
19: 58,442,764 (GRCm39) |
L6Q |
probably damaging |
Het |
| Gm45861 |
T |
G |
8: 28,071,034 (GRCm39) |
S1305A |
unknown |
Het |
| Gse1 |
T |
C |
8: 120,957,387 (GRCm39) |
|
probably benign |
Het |
| Kmt2e |
A |
G |
5: 23,705,485 (GRCm39) |
H1303R |
possibly damaging |
Het |
| Lck |
T |
C |
4: 129,442,658 (GRCm39) |
D499G |
possibly damaging |
Het |
| Lepr |
A |
T |
4: 101,646,484 (GRCm39) |
Y805F |
probably damaging |
Het |
| Lin7a |
A |
T |
10: 107,218,489 (GRCm39) |
Y11F |
possibly damaging |
Het |
| Lrrc43 |
A |
G |
5: 123,641,826 (GRCm39) |
K559E |
probably damaging |
Het |
| Mprip |
G |
A |
11: 59,628,215 (GRCm39) |
G221R |
probably damaging |
Het |
| Myo5c |
T |
C |
9: 75,208,738 (GRCm39) |
V1683A |
probably damaging |
Het |
| Nbeal2 |
G |
A |
9: 110,467,686 (GRCm39) |
R501W |
probably damaging |
Het |
| Ncf1 |
G |
T |
5: 134,254,116 (GRCm39) |
A219E |
possibly damaging |
Het |
| Nckap1l |
T |
C |
15: 103,384,493 (GRCm39) |
I616T |
probably benign |
Het |
| Nlrp2 |
A |
T |
7: 5,331,228 (GRCm39) |
C389* |
probably null |
Het |
| Nrg3 |
T |
C |
14: 38,098,333 (GRCm39) |
E507G |
probably damaging |
Het |
| Or4p19 |
A |
G |
2: 88,242,759 (GRCm39) |
L81P |
probably damaging |
Het |
| P4ha2 |
A |
T |
11: 54,022,072 (GRCm39) |
T532S |
probably benign |
Het |
| Pappa |
A |
T |
4: 65,269,955 (GRCm39) |
H1623L |
probably benign |
Het |
| Paqr6 |
A |
G |
3: 88,273,353 (GRCm39) |
Y115C |
probably damaging |
Het |
| Pcolce2 |
A |
T |
9: 95,560,521 (GRCm39) |
Q190L |
probably benign |
Het |
| Poll |
A |
G |
19: 45,547,277 (GRCm39) |
I65T |
probably benign |
Het |
| Prmt9 |
T |
C |
8: 78,276,086 (GRCm39) |
|
probably benign |
Het |
| Prpf39 |
T |
C |
12: 65,100,074 (GRCm39) |
V130A |
possibly damaging |
Het |
| Prpf6 |
A |
G |
2: 181,262,433 (GRCm39) |
D144G |
probably damaging |
Het |
| Rgs6 |
T |
A |
12: 83,138,878 (GRCm39) |
|
probably benign |
Het |
| Rimbp2 |
A |
G |
5: 128,879,847 (GRCm39) |
|
probably null |
Het |
| Ripor2 |
A |
G |
13: 24,855,829 (GRCm39) |
T90A |
probably benign |
Het |
| Rnf150 |
T |
C |
8: 83,590,706 (GRCm39) |
F23S |
probably damaging |
Het |
| Rpp40 |
G |
A |
13: 36,082,889 (GRCm39) |
R200W |
possibly damaging |
Het |
| Rtp3 |
G |
A |
9: 110,815,714 (GRCm39) |
S217L |
probably benign |
Het |
| Sacs |
A |
C |
14: 61,446,264 (GRCm39) |
K2770T |
probably benign |
Het |
| Scn10a |
A |
T |
9: 119,442,610 (GRCm39) |
I1545N |
probably damaging |
Het |
| Scn2b |
G |
T |
9: 45,037,438 (GRCm39) |
V162L |
probably damaging |
Het |
| Sema6d |
A |
G |
2: 124,506,831 (GRCm39) |
T880A |
probably damaging |
Het |
| Slc36a4 |
A |
G |
9: 15,630,929 (GRCm39) |
D16G |
probably benign |
Het |
| Slc4a8 |
T |
A |
15: 100,689,524 (GRCm39) |
I378K |
probably benign |
Het |
| Smco2 |
T |
A |
6: 146,760,354 (GRCm39) |
L70* |
probably null |
Het |
| Sptb |
C |
T |
12: 76,671,862 (GRCm39) |
V364I |
probably damaging |
Het |
| Susd4 |
A |
G |
1: 182,592,613 (GRCm39) |
H3R |
probably damaging |
Het |
| Tbc1d16 |
T |
C |
11: 119,049,617 (GRCm39) |
Q293R |
probably damaging |
Het |
| Tnfsf9 |
T |
A |
17: 57,414,317 (GRCm39) |
M248K |
possibly damaging |
Het |
| Toporsl |
A |
G |
4: 52,611,211 (GRCm39) |
N368S |
possibly damaging |
Het |
| Trip11 |
T |
C |
12: 101,852,126 (GRCm39) |
E361G |
probably benign |
Het |
| Trrap |
T |
A |
5: 144,728,964 (GRCm39) |
M626K |
possibly damaging |
Het |
| Ttn |
A |
T |
2: 76,773,218 (GRCm39) |
S2395T |
probably damaging |
Het |
| Ubqln3 |
T |
C |
7: 103,790,630 (GRCm39) |
R487G |
probably damaging |
Het |
| Vdac1 |
A |
G |
11: 52,265,193 (GRCm39) |
Y22C |
probably damaging |
Het |
| Vmn1r59 |
C |
T |
7: 5,457,477 (GRCm39) |
M94I |
probably benign |
Het |
| Vmn2r10 |
G |
T |
5: 109,149,894 (GRCm39) |
D383E |
probably damaging |
Het |
| Vmn2r115 |
T |
C |
17: 23,578,785 (GRCm39) |
Y753H |
probably damaging |
Het |
| Vmn2r97 |
G |
T |
17: 19,134,663 (GRCm39) |
C27F |
probably damaging |
Het |
| Wasf1 |
T |
A |
10: 40,812,471 (GRCm39) |
V420E |
unknown |
Het |
| Zfp94 |
A |
T |
7: 24,002,821 (GRCm39) |
L201Q |
probably damaging |
Het |
| Zgpat |
TGGAGGAGGAGGAGGAGGA |
TGGAGGAGGAGGAGGA |
2: 181,007,811 (GRCm39) |
|
probably benign |
Het |
| Zmym4 |
C |
A |
4: 126,762,593 (GRCm39) |
R1410L |
probably damaging |
Het |
|
| Other mutations in Megf6 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01122:Megf6
|
APN |
4 |
154,338,264 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01410:Megf6
|
APN |
4 |
154,337,020 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL01512:Megf6
|
APN |
4 |
154,347,040 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
IGL01824:Megf6
|
APN |
4 |
154,336,691 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02172:Megf6
|
APN |
4 |
154,355,149 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02727:Megf6
|
APN |
4 |
154,337,606 (GRCm39) |
splice site |
probably null |
|
|
IGL02966:Megf6
|
APN |
4 |
154,338,234 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Didactic
|
UTSW |
4 |
154,339,044 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0118:Megf6
|
UTSW |
4 |
154,339,098 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0220:Megf6
|
UTSW |
4 |
154,342,672 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0347:Megf6
|
UTSW |
4 |
154,339,092 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R0383:Megf6
|
UTSW |
4 |
154,349,783 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0417:Megf6
|
UTSW |
4 |
154,352,424 (GRCm39) |
missense |
probably benign |
0.06 |
|
R0526:Megf6
|
UTSW |
4 |
154,343,398 (GRCm39) |
missense |
probably benign |
|
|
R0528:Megf6
|
UTSW |
4 |
154,343,630 (GRCm39) |
missense |
probably benign |
0.04 |
|
R0928:Megf6
|
UTSW |
4 |
154,261,504 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1311:Megf6
|
UTSW |
4 |
154,348,239 (GRCm39) |
splice site |
probably null |
|
|
R1458:Megf6
|
UTSW |
4 |
154,261,578 (GRCm39) |
missense |
probably benign |
0.39 |
|
R1470:Megf6
|
UTSW |
4 |
154,336,876 (GRCm39) |
splice site |
probably benign |
|
|
R1476:Megf6
|
UTSW |
4 |
154,261,578 (GRCm39) |
missense |
probably benign |
0.39 |
|
R1479:Megf6
|
UTSW |
4 |
154,261,578 (GRCm39) |
missense |
probably benign |
0.39 |
|
R1624:Megf6
|
UTSW |
4 |
154,261,578 (GRCm39) |
missense |
probably benign |
0.39 |
|
R1626:Megf6
|
UTSW |
4 |
154,261,578 (GRCm39) |
missense |
probably benign |
0.39 |
|
R1638:Megf6
|
UTSW |
4 |
154,346,967 (GRCm39) |
splice site |
probably benign |
|
|
R1777:Megf6
|
UTSW |
4 |
154,355,147 (GRCm39) |
nonsense |
probably null |
|
|
R1831:Megf6
|
UTSW |
4 |
154,355,134 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1944:Megf6
|
UTSW |
4 |
154,340,523 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R1984:Megf6
|
UTSW |
4 |
154,352,124 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2109:Megf6
|
UTSW |
4 |
154,261,578 (GRCm39) |
missense |
probably benign |
0.39 |
|
R2448:Megf6
|
UTSW |
4 |
154,351,102 (GRCm39) |
splice site |
probably null |
|
|
R2880:Megf6
|
UTSW |
4 |
154,337,006 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4032:Megf6
|
UTSW |
4 |
154,261,550 (GRCm39) |
nonsense |
probably null |
|
|
R4058:Megf6
|
UTSW |
4 |
154,326,989 (GRCm39) |
splice site |
probably benign |
|
|
R4672:Megf6
|
UTSW |
4 |
154,333,909 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4688:Megf6
|
UTSW |
4 |
154,338,271 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4752:Megf6
|
UTSW |
4 |
154,336,895 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4863:Megf6
|
UTSW |
4 |
154,338,738 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4909:Megf6
|
UTSW |
4 |
154,349,848 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4942:Megf6
|
UTSW |
4 |
154,338,277 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4981:Megf6
|
UTSW |
4 |
154,351,907 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R4990:Megf6
|
UTSW |
4 |
154,351,683 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R5001:Megf6
|
UTSW |
4 |
154,352,517 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5189:Megf6
|
UTSW |
4 |
154,336,980 (GRCm39) |
missense |
probably benign |
0.31 |
|
R5210:Megf6
|
UTSW |
4 |
154,354,273 (GRCm39) |
intron |
probably benign |
|
|
R5220:Megf6
|
UTSW |
4 |
154,338,295 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5250:Megf6
|
UTSW |
4 |
154,340,467 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R5697:Megf6
|
UTSW |
4 |
154,342,686 (GRCm39) |
missense |
probably null |
0.15 |
|
R5808:Megf6
|
UTSW |
4 |
154,352,119 (GRCm39) |
missense |
probably benign |
|
|
R5916:Megf6
|
UTSW |
4 |
154,333,882 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R6054:Megf6
|
UTSW |
4 |
154,347,636 (GRCm39) |
missense |
probably benign |
0.06 |
|
R6075:Megf6
|
UTSW |
4 |
154,347,056 (GRCm39) |
nonsense |
probably null |
|
|
R6515:Megf6
|
UTSW |
4 |
154,343,376 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R6599:Megf6
|
UTSW |
4 |
154,342,544 (GRCm39) |
splice site |
probably null |
|
|
R6811:Megf6
|
UTSW |
4 |
154,336,618 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6925:Megf6
|
UTSW |
4 |
154,339,044 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7117:Megf6
|
UTSW |
4 |
154,343,379 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R7163:Megf6
|
UTSW |
4 |
154,351,898 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7345:Megf6
|
UTSW |
4 |
154,351,772 (GRCm39) |
missense |
probably benign |
|
|
R7580:Megf6
|
UTSW |
4 |
154,355,201 (GRCm39) |
nonsense |
probably null |
|
|
R7649:Megf6
|
UTSW |
4 |
154,349,542 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7702:Megf6
|
UTSW |
4 |
154,354,927 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8010:Megf6
|
UTSW |
4 |
154,354,964 (GRCm39) |
missense |
probably benign |
0.13 |
|
R8175:Megf6
|
UTSW |
4 |
154,353,076 (GRCm39) |
nonsense |
probably null |
|
|
R8231:Megf6
|
UTSW |
4 |
154,336,975 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8436:Megf6
|
UTSW |
4 |
154,349,649 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8460:Megf6
|
UTSW |
4 |
154,350,634 (GRCm39) |
nonsense |
probably null |
|
|
R8738:Megf6
|
UTSW |
4 |
154,352,436 (GRCm39) |
missense |
probably benign |
|
|
R8854:Megf6
|
UTSW |
4 |
154,352,469 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8896:Megf6
|
UTSW |
4 |
154,326,860 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9098:Megf6
|
UTSW |
4 |
154,354,160 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9147:Megf6
|
UTSW |
4 |
154,339,130 (GRCm39) |
missense |
probably benign |
0.18 |
|
R9148:Megf6
|
UTSW |
4 |
154,339,130 (GRCm39) |
missense |
probably benign |
0.18 |
|
R9161:Megf6
|
UTSW |
4 |
154,352,172 (GRCm39) |
missense |
probably benign |
0.44 |
|
R9355:Megf6
|
UTSW |
4 |
154,338,282 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9386:Megf6
|
UTSW |
4 |
154,340,534 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9404:Megf6
|
UTSW |
4 |
154,348,225 (GRCm39) |
missense |
|
|
|
R9469:Megf6
|
UTSW |
4 |
154,335,369 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9472:Megf6
|
UTSW |
4 |
154,333,910 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9777:Megf6
|
UTSW |
4 |
154,343,617 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Megf6
|
UTSW |
4 |
154,322,283 (GRCm39) |
missense |
probably benign |
0.12 |
|
Z1177:Megf6
|
UTSW |
4 |
154,354,198 (GRCm39) |
nonsense |
probably null |
|
|
Z1177:Megf6
|
UTSW |
4 |
154,352,204 (GRCm39) |
nonsense |
probably null |
|
|
Z1177:Megf6
|
UTSW |
4 |
154,352,139 (GRCm39) |
missense |
probably damaging |
0.99 |
|
Z1177:Megf6
|
UTSW |
4 |
154,352,138 (GRCm39) |
missense |
possibly damaging |
0.48 |
|
Z1177:Megf6
|
UTSW |
4 |
154,335,306 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- TGATAGGCTAGGACACAGTGTTAC -3'
(R):5'- AACATCATAGGGCAGCCTAGC -3'
Sequencing Primer
(F):5'- CTAGGACACAGTGTTACGGGGG -3'
(R):5'- GGAACTGCCATCCCCAAGG -3'
|
| Posted On |
2019-05-13 |
Incidental Mutation