Incidental Mutation 'R0610:Cep295'
| ID |
54627 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Cep295
|
| Ensembl Gene |
ENSMUSG00000046111 |
| Gene Name |
centrosomal protein 295 |
| Synonyms |
5830418K08Rik, LOC382128 |
| MMRRC Submission |
038799-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably essential
(E-score: 0.952)
|
| Stock # |
R0610 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
9 |
| Chromosomal Location |
15228211-15269084 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to C
at 15234050 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Serine to Alanine
at position 2249
(S2249A)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000123788
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000098979]
[ENSMUST00000161132]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000058041
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000059410
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000098979
AA Change: S2169A
PolyPhen 2
Score 0.435 (Sensitivity: 0.89; Specificity: 0.90)
|
| SMART Domains |
Protein: ENSMUSP00000096578
Gene: ENSMUSG00000046111
AA Change: S2169A
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
159 |
175 |
N/A |
INTRINSIC |
|
coiled coil region
|
258 |
288 |
N/A |
INTRINSIC |
|
coiled coil region
|
536 |
583 |
N/A |
INTRINSIC |
|
coiled coil region
|
861 |
889 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
890 |
1104 |
6.8e-5 |
PROSPERO |
|
internal_repeat_1
|
1277 |
1489 |
6.8e-5 |
PROSPERO |
|
low complexity region
|
1537 |
1548 |
N/A |
INTRINSIC |
|
low complexity region
|
1611 |
1625 |
N/A |
INTRINSIC |
|
coiled coil region
|
1707 |
1736 |
N/A |
INTRINSIC |
|
low complexity region
|
2003 |
2018 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000104206
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000104318
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000159156
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000160238
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000161132
AA Change: S2249A
PolyPhen 2
Score 0.805 (Sensitivity: 0.84; Specificity: 0.93)
|
| SMART Domains |
Protein: ENSMUSP00000123788
Gene: ENSMUSG00000046111
AA Change: S2249A
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
111 |
127 |
N/A |
INTRINSIC |
|
coiled coil region
|
210 |
240 |
N/A |
INTRINSIC |
|
coiled coil region
|
488 |
535 |
N/A |
INTRINSIC |
|
coiled coil region
|
813 |
841 |
N/A |
INTRINSIC |
|
coiled coil region
|
1300 |
1327 |
N/A |
INTRINSIC |
|
low complexity region
|
1489 |
1500 |
N/A |
INTRINSIC |
|
low complexity region
|
1563 |
1577 |
N/A |
INTRINSIC |
|
coiled coil region
|
1659 |
1688 |
N/A |
INTRINSIC |
|
low complexity region
|
2035 |
2050 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000161795
AA Change: S2121A
PolyPhen 2
Score 0.178 (Sensitivity: 0.92; Specificity: 0.87)
|
| SMART Domains |
Protein: ENSMUSP00000125035
Gene: ENSMUSG00000046111
AA Change: S2121A
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
111 |
127 |
N/A |
INTRINSIC |
|
coiled coil region
|
210 |
240 |
N/A |
INTRINSIC |
|
coiled coil region
|
488 |
535 |
N/A |
INTRINSIC |
|
coiled coil region
|
813 |
841 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
842 |
1056 |
7.14e-5 |
PROSPERO |
|
internal_repeat_1
|
1229 |
1441 |
7.14e-5 |
PROSPERO |
|
low complexity region
|
1489 |
1500 |
N/A |
INTRINSIC |
|
low complexity region
|
1563 |
1577 |
N/A |
INTRINSIC |
|
coiled coil region
|
1659 |
1688 |
N/A |
INTRINSIC |
|
low complexity region
|
1955 |
1970 |
N/A |
INTRINSIC |
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000160946
AA Change: S993A
|
| SMART Domains |
Protein: ENSMUSP00000125494
Gene: ENSMUSG00000046111
AA Change: S993A
| Domain | Start | End | E-Value | Type |
|---|
|
coiled coil region
|
92 |
119 |
N/A |
INTRINSIC |
|
low complexity region
|
282 |
293 |
N/A |
INTRINSIC |
|
low complexity region
|
356 |
370 |
N/A |
INTRINSIC |
|
coiled coil region
|
451 |
480 |
N/A |
INTRINSIC |
|
low complexity region
|
828 |
843 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000161533
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000217140
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000214427
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000214696
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000162264
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000217407
|
| Meta Mutation Damage Score |
0.0634 |
| Coding Region Coverage |
- 1x: 99.4%
- 3x: 98.9%
- 10x: 97.4%
- 20x: 94.7%
|
| Validation Efficiency |
99% (97/98) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 94 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4930433I11Rik |
A |
T |
7: 40,642,480 (GRCm39) |
T141S |
probably benign |
Het |
| 4930578I06Rik |
G |
A |
14: 64,223,714 (GRCm39) |
R21* |
probably null |
Het |
| Abca15 |
A |
G |
7: 119,965,009 (GRCm39) |
E757G |
possibly damaging |
Het |
| Abca5 |
T |
C |
11: 110,192,353 (GRCm39) |
T720A |
probably benign |
Het |
| Actr5 |
T |
A |
2: 158,474,376 (GRCm39) |
|
probably null |
Het |
| Adgrl3 |
T |
C |
5: 81,841,563 (GRCm39) |
|
probably benign |
Het |
| Adra1a |
A |
G |
14: 66,875,241 (GRCm39) |
D72G |
probably damaging |
Het |
| Ahcyl |
T |
C |
16: 45,974,264 (GRCm39) |
E371G |
probably damaging |
Het |
| Ahnak |
G |
T |
19: 8,985,242 (GRCm39) |
L2175F |
probably benign |
Het |
| AK157302 |
A |
G |
13: 21,679,833 (GRCm39) |
T120A |
possibly damaging |
Het |
| Apol7a |
G |
A |
15: 77,273,454 (GRCm39) |
A336V |
probably benign |
Het |
| Asic1 |
C |
A |
15: 99,596,780 (GRCm39) |
H525Q |
probably benign |
Het |
| Atxn7l2 |
T |
C |
3: 108,112,090 (GRCm39) |
D335G |
possibly damaging |
Het |
| Bpgm |
G |
T |
6: 34,481,284 (GRCm39) |
R227L |
possibly damaging |
Het |
| Calm4 |
T |
A |
13: 3,888,320 (GRCm39) |
V142E |
possibly damaging |
Het |
| Catsperg1 |
A |
T |
7: 28,890,044 (GRCm39) |
L721Q |
probably damaging |
Het |
| Cdh26 |
A |
G |
2: 178,091,691 (GRCm39) |
I83M |
probably damaging |
Het |
| Cfhr4 |
G |
A |
1: 139,629,584 (GRCm39) |
T799I |
probably benign |
Het |
| Cln3 |
A |
G |
7: 126,179,361 (GRCm39) |
F139L |
probably damaging |
Het |
| Cmpk2 |
T |
A |
12: 26,528,055 (GRCm39) |
L424Q |
possibly damaging |
Het |
| Col12a1 |
A |
T |
9: 79,615,130 (GRCm39) |
V53E |
probably benign |
Het |
| Csmd1 |
G |
A |
8: 15,968,208 (GRCm39) |
R3140C |
possibly damaging |
Het |
| Dagla |
A |
G |
19: 10,248,922 (GRCm39) |
W11R |
probably damaging |
Het |
| Dbx2 |
C |
T |
15: 95,522,778 (GRCm39) |
V310M |
probably benign |
Het |
| Disp2 |
T |
A |
2: 118,622,717 (GRCm39) |
C1150S |
probably benign |
Het |
| Dock3 |
T |
C |
9: 106,900,987 (GRCm39) |
D326G |
probably damaging |
Het |
| Dph1 |
G |
T |
11: 75,076,783 (GRCm39) |
|
probably benign |
Het |
| Dyrk1b |
C |
A |
7: 27,886,059 (GRCm39) |
T594K |
probably damaging |
Het |
| Evx2 |
C |
A |
2: 74,486,331 (GRCm39) |
A353S |
probably benign |
Het |
| Garin1b |
T |
A |
6: 29,326,576 (GRCm39) |
V231E |
probably benign |
Het |
| Greb1 |
A |
C |
12: 16,746,443 (GRCm39) |
S1276A |
probably benign |
Het |
| Hhipl1 |
T |
A |
12: 108,285,661 (GRCm39) |
C490* |
probably null |
Het |
| Hmmr |
G |
T |
11: 40,606,729 (GRCm39) |
T231K |
probably damaging |
Het |
| Hspa4l |
A |
C |
3: 40,733,832 (GRCm39) |
E526D |
probably benign |
Het |
| Ibsp |
A |
G |
5: 104,458,000 (GRCm39) |
E179G |
probably benign |
Het |
| Ift140 |
C |
T |
17: 25,254,777 (GRCm39) |
A150V |
probably benign |
Het |
| Igf2bp2 |
A |
G |
16: 21,889,059 (GRCm39) |
S416P |
probably benign |
Het |
| Ighe |
T |
C |
12: 113,235,363 (GRCm39) |
K294E |
unknown |
Het |
| Ino80 |
G |
A |
2: 119,213,441 (GRCm39) |
R1249C |
probably damaging |
Het |
| Iqca1 |
C |
A |
1: 90,070,453 (GRCm39) |
G133V |
probably null |
Het |
| Kng2 |
T |
A |
16: 22,819,344 (GRCm39) |
N231Y |
possibly damaging |
Het |
| Lca5 |
A |
T |
9: 83,281,792 (GRCm39) |
C331S |
probably benign |
Het |
| Lrrc1 |
A |
G |
9: 77,379,488 (GRCm39) |
I101T |
possibly damaging |
Het |
| Lrrk2 |
A |
T |
15: 91,699,619 (GRCm39) |
I2489L |
probably benign |
Het |
| Lyz3 |
A |
G |
10: 117,073,635 (GRCm39) |
F66S |
probably benign |
Het |
| Mapk9 |
A |
C |
11: 49,754,400 (GRCm39) |
N51T |
probably benign |
Het |
| Marf1 |
C |
T |
16: 13,960,398 (GRCm39) |
A549T |
probably damaging |
Het |
| Nek2 |
T |
A |
1: 191,554,627 (GRCm39) |
V113D |
probably damaging |
Het |
| Nr4a3 |
C |
A |
4: 48,051,903 (GRCm39) |
A248E |
probably benign |
Het |
| Nrp1 |
T |
C |
8: 129,229,099 (GRCm39) |
I859T |
probably damaging |
Het |
| Olfm5 |
A |
T |
7: 103,803,652 (GRCm39) |
Y195* |
probably null |
Het |
| Or13j1 |
T |
A |
4: 43,706,400 (GRCm39) |
H56L |
possibly damaging |
Het |
| Or1n2 |
T |
A |
2: 36,797,671 (GRCm39) |
W238R |
probably damaging |
Het |
| Or8g35 |
A |
G |
9: 39,381,119 (GRCm39) |
L301P |
probably damaging |
Het |
| Oxtr |
C |
T |
6: 112,454,138 (GRCm39) |
R42Q |
probably benign |
Het |
| Pcnx2 |
A |
G |
8: 126,566,426 (GRCm39) |
W1006R |
probably damaging |
Het |
| Pdpk1 |
T |
C |
17: 24,317,145 (GRCm39) |
|
probably null |
Het |
| Ryr2 |
T |
A |
13: 11,637,838 (GRCm39) |
H3731L |
probably damaging |
Het |
| Sdr16c5 |
T |
G |
4: 4,016,116 (GRCm39) |
E103D |
possibly damaging |
Het |
| Setdb2 |
A |
C |
14: 59,654,919 (GRCm39) |
S324A |
possibly damaging |
Het |
| Slc17a3 |
C |
T |
13: 24,039,841 (GRCm39) |
S293F |
probably damaging |
Het |
| Slc17a8 |
A |
T |
10: 89,412,488 (GRCm39) |
I499K |
probably damaging |
Het |
| Slc2a9 |
T |
A |
5: 38,537,285 (GRCm39) |
I389F |
probably damaging |
Het |
| Slc30a1 |
T |
C |
1: 191,641,536 (GRCm39) |
V394A |
probably damaging |
Het |
| Slc41a2 |
A |
G |
10: 83,119,592 (GRCm39) |
I390T |
possibly damaging |
Het |
| Slco1a1 |
A |
G |
6: 141,864,187 (GRCm39) |
|
probably null |
Het |
| Slit2 |
A |
G |
5: 48,433,016 (GRCm39) |
K1053E |
possibly damaging |
Het |
| Smarca2 |
T |
A |
19: 26,668,791 (GRCm39) |
L930Q |
probably damaging |
Het |
| Snx6 |
T |
C |
12: 54,798,574 (GRCm39) |
H387R |
probably damaging |
Het |
| Sox5 |
A |
T |
6: 143,779,165 (GRCm39) |
M622K |
possibly damaging |
Het |
| Ston1 |
C |
A |
17: 88,942,709 (GRCm39) |
N38K |
possibly damaging |
Het |
| Strbp |
C |
T |
2: 37,474,089 (GRCm39) |
V658I |
probably damaging |
Het |
| Strn3 |
T |
C |
12: 51,657,231 (GRCm39) |
|
probably null |
Het |
| Suco |
T |
G |
1: 161,687,072 (GRCm39) |
D96A |
probably benign |
Het |
| Suco |
A |
G |
1: 161,691,601 (GRCm39) |
|
probably benign |
Het |
| Sytl2 |
A |
T |
7: 90,030,061 (GRCm39) |
|
probably benign |
Het |
| Tmem41b |
T |
A |
7: 109,580,290 (GRCm39) |
M25L |
probably benign |
Het |
| Tmem41b |
T |
A |
7: 109,580,292 (GRCm39) |
D91V |
probably damaging |
Het |
| Tmem50b |
C |
T |
16: 91,380,174 (GRCm39) |
A68T |
probably damaging |
Het |
| Tmprss11e |
G |
A |
5: 86,855,206 (GRCm39) |
Q400* |
probably null |
Het |
| Tnfsf13b |
G |
A |
8: 10,081,661 (GRCm39) |
|
probably null |
Het |
| Trappc8 |
A |
G |
18: 20,970,245 (GRCm39) |
V916A |
probably damaging |
Het |
| Trdn |
G |
T |
10: 33,350,449 (GRCm39) |
V673F |
probably damaging |
Het |
| Trim28 |
G |
T |
7: 12,759,711 (GRCm39) |
|
probably benign |
Het |
| Txnrd2 |
T |
C |
16: 18,291,632 (GRCm39) |
V427A |
probably damaging |
Het |
| Uggt1 |
T |
C |
1: 36,204,587 (GRCm39) |
|
probably benign |
Het |
| Vmn1r36 |
A |
G |
6: 66,693,404 (GRCm39) |
L51P |
probably damaging |
Het |
| Vmn1r63 |
T |
A |
7: 5,806,063 (GRCm39) |
M190L |
possibly damaging |
Het |
| Vmn2r116 |
T |
A |
17: 23,606,286 (GRCm39) |
N399K |
probably damaging |
Het |
| Vmn2r117 |
T |
C |
17: 23,694,488 (GRCm39) |
N453S |
probably benign |
Het |
| Wbp1l |
T |
A |
19: 46,643,109 (GRCm39) |
I370N |
probably damaging |
Het |
| Zfp445 |
T |
C |
9: 122,682,046 (GRCm39) |
K632E |
probably benign |
Het |
| Zfp850 |
C |
T |
7: 27,688,819 (GRCm39) |
R463H |
probably damaging |
Het |
| Zyg11a |
A |
G |
4: 108,062,054 (GRCm39) |
L249P |
probably damaging |
Het |
|
| Other mutations in Cep295 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00337:Cep295
|
APN |
9 |
15,237,368 (GRCm39) |
splice site |
probably null |
|
|
IGL00769:Cep295
|
APN |
9 |
15,237,440 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00771:Cep295
|
APN |
9 |
15,233,861 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00850:Cep295
|
APN |
9 |
15,234,148 (GRCm39) |
missense |
probably benign |
0.36 |
|
IGL01505:Cep295
|
APN |
9 |
15,229,345 (GRCm39) |
missense |
probably benign |
0.08 |
|
IGL01510:Cep295
|
APN |
9 |
15,265,922 (GRCm39) |
nonsense |
probably null |
|
|
IGL01759:Cep295
|
APN |
9 |
15,234,855 (GRCm39) |
splice site |
probably null |
|
|
IGL02415:Cep295
|
APN |
9 |
15,264,316 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02447:Cep295
|
APN |
9 |
15,243,807 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL02502:Cep295
|
APN |
9 |
15,262,209 (GRCm39) |
splice site |
probably benign |
|
|
IGL02665:Cep295
|
APN |
9 |
15,237,928 (GRCm39) |
splice site |
probably benign |
|
|
IGL02718:Cep295
|
APN |
9 |
15,237,049 (GRCm39) |
splice site |
probably null |
|
|
IGL02995:Cep295
|
APN |
9 |
15,244,608 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03024:Cep295
|
APN |
9 |
15,236,868 (GRCm39) |
missense |
probably benign |
|
|
R0196:Cep295
|
UTSW |
9 |
15,249,509 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R0398:Cep295
|
UTSW |
9 |
15,266,032 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R0595:Cep295
|
UTSW |
9 |
15,243,487 (GRCm39) |
nonsense |
probably null |
|
|
R0616:Cep295
|
UTSW |
9 |
15,243,618 (GRCm39) |
nonsense |
probably null |
|
|
R0840:Cep295
|
UTSW |
9 |
15,245,611 (GRCm39) |
missense |
probably benign |
0.02 |
|
R1215:Cep295
|
UTSW |
9 |
15,239,178 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1376:Cep295
|
UTSW |
9 |
15,252,164 (GRCm39) |
splice site |
probably benign |
|
|
R1381:Cep295
|
UTSW |
9 |
15,233,861 (GRCm39) |
missense |
probably benign |
0.02 |
|
R1484:Cep295
|
UTSW |
9 |
15,246,080 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1557:Cep295
|
UTSW |
9 |
15,243,306 (GRCm39) |
nonsense |
probably null |
|
|
R1655:Cep295
|
UTSW |
9 |
15,252,179 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1682:Cep295
|
UTSW |
9 |
15,245,217 (GRCm39) |
missense |
probably benign |
0.02 |
|
R1700:Cep295
|
UTSW |
9 |
15,252,179 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1734:Cep295
|
UTSW |
9 |
15,252,179 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1736:Cep295
|
UTSW |
9 |
15,252,179 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1743:Cep295
|
UTSW |
9 |
15,252,179 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1765:Cep295
|
UTSW |
9 |
15,239,200 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1889:Cep295
|
UTSW |
9 |
15,243,399 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R1895:Cep295
|
UTSW |
9 |
15,243,399 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R1994:Cep295
|
UTSW |
9 |
15,252,179 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1995:Cep295
|
UTSW |
9 |
15,252,179 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2071:Cep295
|
UTSW |
9 |
15,252,860 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2161:Cep295
|
UTSW |
9 |
15,264,354 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2195:Cep295
|
UTSW |
9 |
15,243,617 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2354:Cep295
|
UTSW |
9 |
15,246,080 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R2427:Cep295
|
UTSW |
9 |
15,245,534 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2992:Cep295
|
UTSW |
9 |
15,244,043 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3873:Cep295
|
UTSW |
9 |
15,244,661 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3981:Cep295
|
UTSW |
9 |
15,228,363 (GRCm39) |
utr 3 prime |
probably benign |
|
|
R4201:Cep295
|
UTSW |
9 |
15,243,834 (GRCm39) |
missense |
probably benign |
0.19 |
|
R4297:Cep295
|
UTSW |
9 |
15,233,950 (GRCm39) |
missense |
probably benign |
0.19 |
|
R4543:Cep295
|
UTSW |
9 |
15,246,549 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R4584:Cep295
|
UTSW |
9 |
15,246,095 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R4724:Cep295
|
UTSW |
9 |
15,242,128 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4878:Cep295
|
UTSW |
9 |
15,246,252 (GRCm39) |
missense |
probably benign |
0.11 |
|
R4884:Cep295
|
UTSW |
9 |
15,263,056 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4934:Cep295
|
UTSW |
9 |
15,244,456 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R4990:Cep295
|
UTSW |
9 |
15,243,434 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5057:Cep295
|
UTSW |
9 |
15,233,979 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5153:Cep295
|
UTSW |
9 |
15,268,925 (GRCm39) |
missense |
probably benign |
0.32 |
|
R5180:Cep295
|
UTSW |
9 |
15,243,416 (GRCm39) |
missense |
probably benign |
|
|
R5285:Cep295
|
UTSW |
9 |
15,233,887 (GRCm39) |
missense |
probably benign |
0.14 |
|
R5360:Cep295
|
UTSW |
9 |
15,238,029 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5419:Cep295
|
UTSW |
9 |
15,235,533 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5432:Cep295
|
UTSW |
9 |
15,262,991 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R5625:Cep295
|
UTSW |
9 |
15,252,187 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5637:Cep295
|
UTSW |
9 |
15,245,108 (GRCm39) |
splice site |
probably null |
|
|
R5645:Cep295
|
UTSW |
9 |
15,246,404 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R5645:Cep295
|
UTSW |
9 |
15,244,090 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5678:Cep295
|
UTSW |
9 |
15,234,154 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5688:Cep295
|
UTSW |
9 |
15,243,282 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5807:Cep295
|
UTSW |
9 |
15,243,828 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5824:Cep295
|
UTSW |
9 |
15,236,952 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R5837:Cep295
|
UTSW |
9 |
15,258,280 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5915:Cep295
|
UTSW |
9 |
15,252,775 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5988:Cep295
|
UTSW |
9 |
15,252,770 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6239:Cep295
|
UTSW |
9 |
15,233,927 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R6332:Cep295
|
UTSW |
9 |
15,246,210 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R6383:Cep295
|
UTSW |
9 |
15,244,050 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6737:Cep295
|
UTSW |
9 |
15,243,647 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R6929:Cep295
|
UTSW |
9 |
15,244,358 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7428:Cep295
|
UTSW |
9 |
15,244,794 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
R7697:Cep295
|
UTSW |
9 |
15,266,006 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7963:Cep295
|
UTSW |
9 |
15,244,737 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R8055:Cep295
|
UTSW |
9 |
15,244,905 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8069:Cep295
|
UTSW |
9 |
15,233,882 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R8092:Cep295
|
UTSW |
9 |
15,244,278 (GRCm39) |
missense |
probably benign |
0.17 |
|
R8117:Cep295
|
UTSW |
9 |
15,245,660 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8140:Cep295
|
UTSW |
9 |
15,252,829 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8178:Cep295
|
UTSW |
9 |
15,244,836 (GRCm39) |
missense |
|
|
|
R8323:Cep295
|
UTSW |
9 |
15,264,357 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R8323:Cep295
|
UTSW |
9 |
15,249,529 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R8339:Cep295
|
UTSW |
9 |
15,236,846 (GRCm39) |
missense |
|
|
|
R8351:Cep295
|
UTSW |
9 |
15,234,202 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8367:Cep295
|
UTSW |
9 |
15,245,826 (GRCm39) |
missense |
probably benign |
0.09 |
|
R8725:Cep295
|
UTSW |
9 |
15,243,715 (GRCm39) |
nonsense |
probably null |
|
|
R8919:Cep295
|
UTSW |
9 |
15,238,007 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9015:Cep295
|
UTSW |
9 |
15,244,264 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9054:Cep295
|
UTSW |
9 |
15,235,551 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R9088:Cep295
|
UTSW |
9 |
15,233,815 (GRCm39) |
missense |
probably benign |
0.09 |
|
R9159:Cep295
|
UTSW |
9 |
15,252,904 (GRCm39) |
missense |
probably benign |
0.05 |
|
R9243:Cep295
|
UTSW |
9 |
15,243,605 (GRCm39) |
missense |
probably benign |
0.36 |
|
R9408:Cep295
|
UTSW |
9 |
15,244,619 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9424:Cep295
|
UTSW |
9 |
15,244,499 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9455:Cep295
|
UTSW |
9 |
15,245,046 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R9607:Cep295
|
UTSW |
9 |
15,234,009 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9648:Cep295
|
UTSW |
9 |
15,234,903 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9659:Cep295
|
UTSW |
9 |
15,233,846 (GRCm39) |
missense |
probably benign |
0.19 |
|
R9731:Cep295
|
UTSW |
9 |
15,245,262 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
X0065:Cep295
|
UTSW |
9 |
15,234,187 (GRCm39) |
missense |
probably benign |
0.36 |
|
Z1176:Cep295
|
UTSW |
9 |
15,268,993 (GRCm39) |
missense |
probably damaging |
0.99 |
|
Z1177:Cep295
|
UTSW |
9 |
15,242,113 (GRCm39) |
missense |
|
|
|
| Predicted Primers |
PCR Primer
(F):5'- ACGCTGGCATTCTTCCAGTCAC -3'
(R):5'- CAGCCCTCAACAGAGGATTTGACTC -3'
Sequencing Primer
(F):5'- GGCATTCTTCCAGTCACAATAG -3'
(R):5'- ACAGAGGATTTGACTCCAGCTTG -3'
|
| Posted On |
2013-07-11 |
Incidental Mutation