Mutagenetix > Incidental Mutation

Incidental Mutation 'R7034:Pcnx2'

546536

Institutional Source

Beutler Lab

Gene Symbol

Pcnx2

Ensembl Gene

ENSMUSG00000060212

Gene Name

pecanex homolog 2

Synonyms

Pcnxl2, E330039K12Rik

MMRRC Submission

045135-MU

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

R7034 (G1)

Quality Score

225.009

Status

Not validated

Chromosome

Chromosomal Location

126478247-126625056 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

T to C at 126512041 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Threonine to Alanine at position 1422 (T1422A)

Ref Sequence

ENSEMBL: ENSMUSP00000042294 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000047239]

AlphaFold

Q5DU28

Predicted Effect

probably damaging
Transcript: ENSMUST00000047239
AA Change: T1422A

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)

SMART Domains

Protein: ENSMUSP00000042294
Gene: ENSMUSG00000060212
AA Change: T1422A

Domain	Start	End	E-Value	Type
transmembrane domain	36	53	N/A	INTRINSIC
transmembrane domain	60	82	N/A	INTRINSIC
low complexity region	94	104	N/A	INTRINSIC
low complexity region	391	415	N/A	INTRINSIC
low complexity region	457	476	N/A	INTRINSIC
low complexity region	727	742	N/A	INTRINSIC
low complexity region	806	817	N/A	INTRINSIC
transmembrane domain	823	842	N/A	INTRINSIC
transmembrane domain	849	866	N/A	INTRINSIC
transmembrane domain	881	902	N/A	INTRINSIC
transmembrane domain	934	956	N/A	INTRINSIC
transmembrane domain	976	998	N/A	INTRINSIC
transmembrane domain	1011	1030	N/A	INTRINSIC
transmembrane domain	1080	1102	N/A	INTRINSIC
transmembrane domain	1104	1126	N/A	INTRINSIC
Pfam:Pecanex_C	1603	1828	3.5e-113	PFAM
low complexity region	1864	1889	N/A	INTRINSIC
low complexity region	1968	1981	N/A	INTRINSIC
low complexity region	2004	2019	N/A	INTRINSIC

Coding Region Coverage

1x: 100.0%
3x: 100.0%
10x: 99.7%
20x: 99.1%

Validation Efficiency

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene contains coding mononucleotide repeats that are associated with tumors of high mcrosatellite instability (MSI-H). Defects in this gene are involved in the tumorigenesis of MSI-H colorectal carcinomas. [provided by RefSeq, Jun 2016]

Allele List at MGI

Other mutations in this stock

Total: 84 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
1700017N19Rik	T	A	10: 100,445,118 (GRCm39)		probably null	Het
Adamts1	T	A	16: 85,599,634 (GRCm39)		probably benign	Het
Aff4	A	G	11: 53,299,236 (GRCm39)	K979E	probably damaging	Het
Aftph	A	T	11: 20,642,498 (GRCm39)	M845K	probably damaging	Het
Akt2	T	C	7: 27,336,437 (GRCm39)		probably null	Het
Aldh1a7	A	T	19: 20,685,542 (GRCm39)	L336Q	possibly damaging	Het
Ank3	C	T	10: 69,835,209 (GRCm39)	T680M	probably damaging	Het
Apeh	T	C	9: 107,971,470 (GRCm39)	E59G	possibly damaging	Het
Armc8	C	T	9: 99,366,018 (GRCm39)		probably null	Het
Armh3	A	G	19: 45,953,688 (GRCm39)	I195T	probably damaging	Het
Atp2b1	C	T	10: 98,823,172 (GRCm39)	T244I	probably damaging	Het
Btaf1	C	A	19: 36,981,869 (GRCm39)	T1633K	probably benign	Het
Cacng8	A	G	7: 3,463,819 (GRCm39)	S324G	probably benign	Het
Calcr	T	A	6: 3,692,543 (GRCm39)	Q400L	probably damaging	Het
Caprin2	G	A	6: 148,749,703 (GRCm39)	P536S	possibly damaging	Het
Ccdc54	A	T	16: 50,410,951 (GRCm39)	M105K	probably benign	Het
Ccna1	T	C	3: 54,953,460 (GRCm39)	E381G	possibly damaging	Het
Cd2ap	A	T	17: 43,109,490 (GRCm39)	L623Q	probably damaging	Het
Cdkl3	A	G	11: 51,918,042 (GRCm39)	E415G	probably benign	Het
Chd5	C	A	4: 152,445,398 (GRCm39)	L430I	possibly damaging	Het
Clspn	G	A	4: 126,474,775 (GRCm39)	E975K	possibly damaging	Het
Cobl	C	A	11: 12,204,177 (GRCm39)	V835F	probably damaging	Het
D430041D05Rik	C	A	2: 104,022,883 (GRCm39)	R1037L	probably damaging	Het
Derl1	A	G	15: 57,742,443 (GRCm39)		probably null	Het
Dhrs9	T	G	2: 69,223,520 (GRCm39)	N89K	probably benign	Het
Erich1	A	G	8: 14,114,330 (GRCm39)	I60T	probably benign	Het
Fam184a	A	T	10: 53,570,910 (GRCm39)	S408T	possibly damaging	Het
Fcgr4	T	A	1: 170,847,657 (GRCm39)	M85K	probably benign	Het
Foxj3	A	G	4: 119,476,497 (GRCm39)	E259G	probably damaging	Het
Galnt11	T	C	5: 25,463,811 (GRCm39)	I361T	probably damaging	Het
Gck	A	G	11: 5,851,747 (GRCm39)	S441P	probably damaging	Het
Gdap1l1	G	T	2: 163,288,065 (GRCm39)	V98F	probably damaging	Het
Gramd1a	A	G	7: 30,832,181 (GRCm39)		probably null	Het
H2ac21	C	T	3: 96,127,304 (GRCm39)	Q25*	probably null	Het
Herc3	A	T	6: 58,853,840 (GRCm39)	M629L	probably benign	Het
Hoxc12	G	A	15: 102,846,795 (GRCm39)	G229D	probably damaging	Het
Hycc2	T	A	1: 58,574,696 (GRCm39)	M282L	probably benign	Het
Itga9	T	C	9: 118,527,433 (GRCm39)	L528P	probably benign	Het
Krt39	A	C	11: 99,412,062 (GRCm39)	V8G	probably benign	Het
Krt71	A	G	15: 101,646,772 (GRCm39)	I312T	probably benign	Het
Lrrc37	T	A	11: 103,506,638 (GRCm39)		probably benign	Het
Mllt11	A	G	3: 95,127,744 (GRCm39)	Y9H	probably damaging	Het
Mrgpra3	G	T	7: 47,239,838 (GRCm39)	N29K	possibly damaging	Het
Mug1	A	G	6: 121,850,603 (GRCm39)	T700A	probably benign	Het
Myl1	T	C	1: 66,969,395 (GRCm39)	N79S	probably damaging	Het
Myo18b	G	A	5: 112,871,770 (GRCm39)	Q2104*	probably null	Het
Nalf1	G	A	8: 9,820,589 (GRCm39)	P144S	possibly damaging	Het
Ndufs2	T	C	1: 171,065,877 (GRCm39)	D256G	probably benign	Het
Nek5	T	C	8: 22,597,739 (GRCm39)	N280S	probably benign	Het
Nwd2	A	T	5: 63,962,258 (GRCm39)	N614I	probably damaging	Het
Or6c88	G	A	10: 129,406,941 (GRCm39)	C139Y	possibly damaging	Het
Parp1	G	T	1: 180,425,817 (GRCm39)	K849N	possibly damaging	Het
Plce1	A	G	19: 38,727,801 (GRCm39)	N1520S	probably damaging	Het
Ppcdc	T	C	9: 57,322,453 (GRCm39)	T149A	probably damaging	Het
Ppl	A	G	16: 4,905,366 (GRCm39)	V1643A	probably benign	Het
Pramel23	A	T	4: 143,423,898 (GRCm39)	I297N	probably damaging	Het
Prrx1	T	A	1: 163,075,907 (GRCm39)	M220L	probably benign	Het
Pspc1	A	C	14: 56,996,085 (GRCm39)		probably null	Het
Ptpn20	A	G	14: 33,336,392 (GRCm39)	*44W	probably null	Het
Qars1	T	A	9: 108,391,976 (GRCm39)	V83E	probably damaging	Het
Rbm33	T	C	5: 28,599,496 (GRCm39)	M956T	unknown	Het
Sash1	C	A	10: 8,605,847 (GRCm39)	E848*	probably null	Het
Scai	T	A	2: 39,011,147 (GRCm39)	Y163F	probably damaging	Het
Serpinf2	A	T	11: 75,329,244 (GRCm39)		probably benign	Het
Sgo2b	T	A	8: 64,379,868 (GRCm39)	H988L	probably benign	Het
Sh2b2	G	A	5: 136,247,739 (GRCm39)	T604I	probably benign	Het
Skint4	A	T	4: 112,015,281 (GRCm39)	I449F	possibly damaging	Het
Slc30a2	A	G	4: 134,074,653 (GRCm39)	I88V	possibly damaging	Het
Smug1	A	G	15: 103,064,369 (GRCm39)	L184P	probably damaging	Het
Spatc1	A	G	15: 76,168,080 (GRCm39)	T180A	probably benign	Het
Ssr1	A	T	13: 38,178,001 (GRCm39)	L20Q	probably null	Het
Supt4a	A	G	11: 87,634,084 (GRCm39)	E100G	probably damaging	Het
Teddm2	T	C	1: 153,726,320 (GRCm39)	I132V	probably benign	Het
Tmem131	C	T	1: 36,832,054 (GRCm39)	G1861E	possibly damaging	Het
Tpr	A	T	1: 150,299,358 (GRCm39)	H1186L	probably benign	Het
Trim34b	A	T	7: 103,978,743 (GRCm39)		probably benign	Het
Trpm2	T	C	10: 77,748,426 (GRCm39)	M1415V	probably benign	Het
Ttll12	A	G	15: 83,471,086 (GRCm39)	F264S	probably benign	Het
Vmn2r59	T	C	7: 41,695,644 (GRCm39)	E256G	probably benign	Het
Vmn2r93	A	T	17: 18,546,672 (GRCm39)	H848L	probably benign	Het
Vps35l	T	C	7: 118,372,315 (GRCm39)	S290P	probably damaging	Het
Wdfy3	G	A	5: 102,055,384 (GRCm39)	T1562I	probably damaging	Het
Ybey	T	C	10: 76,304,197 (GRCm39)	S2G	possibly damaging	Het
Zfp346	A	T	13: 55,280,200 (GRCm39)	Q308L	probably benign	Het

Other mutations in Pcnx2

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00898:Pcnx2	APN	8	126,614,324 (GRCm39)	missense	probably damaging	1.00
IGL00900:Pcnx2	APN	8	126,589,975 (GRCm39)	splice site	probably benign
IGL01134:Pcnx2	APN	8	126,589,889 (GRCm39)	missense	probably benign
IGL01370:Pcnx2	APN	8	126,528,222 (GRCm39)	missense	probably damaging	0.96
IGL01452:Pcnx2	APN	8	126,564,771 (GRCm39)	missense	probably damaging	1.00
IGL01477:Pcnx2	APN	8	126,512,044 (GRCm39)	missense	probably damaging	1.00
IGL01610:Pcnx2	APN	8	126,566,372 (GRCm39)	missense	possibly damaging	0.67
IGL01640:Pcnx2	APN	8	126,528,297 (GRCm39)	missense	probably benign	0.14
IGL01645:Pcnx2	APN	8	126,614,656 (GRCm39)	missense	probably damaging	1.00
IGL01876:Pcnx2	APN	8	126,592,770 (GRCm39)	missense	probably benign	0.31
IGL01933:Pcnx2	APN	8	126,488,393 (GRCm39)	missense	probably damaging	1.00
IGL02208:Pcnx2	APN	8	126,478,894 (GRCm39)	missense	probably benign	0.30
IGL02573:Pcnx2	APN	8	126,582,012 (GRCm39)	missense	probably benign	0.34
IGL02810:Pcnx2	APN	8	126,613,942 (GRCm39)	missense	probably benign	0.03
IGL02859:Pcnx2	APN	8	126,589,912 (GRCm39)	missense	probably damaging	1.00
IGL02879:Pcnx2	APN	8	126,498,796 (GRCm39)	missense	probably damaging	1.00
IGL03202:Pcnx2	APN	8	126,498,783 (GRCm39)	missense	probably damaging	0.98
IGL03259:Pcnx2	APN	8	126,480,388 (GRCm39)	missense	probably benign	0.19
IGL03395:Pcnx2	APN	8	126,614,262 (GRCm39)	missense	probably benign	0.00
IGL03410:Pcnx2	APN	8	126,613,779 (GRCm39)	missense	probably damaging	1.00
gallen	UTSW	8	126,617,859 (GRCm39)	missense	probably damaging	1.00
hotzone	UTSW	8	126,617,880 (GRCm39)	missense	probably benign	0.00
R0107:Pcnx2	UTSW	8	126,480,325 (GRCm39)	missense	probably benign	0.29
R0477:Pcnx2	UTSW	8	126,488,306 (GRCm39)	missense	probably damaging	0.99
R0610:Pcnx2	UTSW	8	126,566,426 (GRCm39)	missense	probably damaging	1.00
R0645:Pcnx2	UTSW	8	126,487,459 (GRCm39)	missense	possibly damaging	0.64
R0894:Pcnx2	UTSW	8	126,613,665 (GRCm39)	splice site	probably benign
R1083:Pcnx2	UTSW	8	126,498,843 (GRCm39)	missense	probably damaging	1.00
R1199:Pcnx2	UTSW	8	126,614,053 (GRCm39)	missense	possibly damaging	0.60
R1296:Pcnx2	UTSW	8	126,500,572 (GRCm39)	missense	probably damaging	1.00
R1445:Pcnx2	UTSW	8	126,479,023 (GRCm39)	missense	probably damaging	0.99
R1467:Pcnx2	UTSW	8	126,480,289 (GRCm39)	missense	possibly damaging	0.77
R1467:Pcnx2	UTSW	8	126,480,289 (GRCm39)	missense	possibly damaging	0.77
R1524:Pcnx2	UTSW	8	126,617,880 (GRCm39)	missense	probably benign	0.00
R1537:Pcnx2	UTSW	8	126,604,188 (GRCm39)	missense	possibly damaging	0.94
R1574:Pcnx2	UTSW	8	126,500,669 (GRCm39)	missense	probably damaging	1.00
R1574:Pcnx2	UTSW	8	126,500,669 (GRCm39)	missense	probably damaging	1.00
R1593:Pcnx2	UTSW	8	126,486,012 (GRCm39)	missense	probably benign	0.11
R1598:Pcnx2	UTSW	8	126,498,825 (GRCm39)	missense	probably benign	0.03
R1603:Pcnx2	UTSW	8	126,566,365 (GRCm39)	missense	probably damaging	1.00
R1697:Pcnx2	UTSW	8	126,577,087 (GRCm39)	missense	probably damaging	1.00
R1759:Pcnx2	UTSW	8	126,500,717 (GRCm39)	missense	probably damaging	1.00
R1855:Pcnx2	UTSW	8	126,534,735 (GRCm39)	splice site	probably benign
R1863:Pcnx2	UTSW	8	126,545,525 (GRCm39)	missense	probably damaging	0.98
R1930:Pcnx2	UTSW	8	126,614,453 (GRCm39)	missense	probably benign	0.10
R1967:Pcnx2	UTSW	8	126,542,422 (GRCm39)	missense	possibly damaging	0.51
R1974:Pcnx2	UTSW	8	126,614,110 (GRCm39)	missense	probably benign	0.00
R1998:Pcnx2	UTSW	8	126,613,882 (GRCm39)	missense	probably damaging	1.00
R2034:Pcnx2	UTSW	8	126,545,406 (GRCm39)	critical splice donor site	probably null
R2072:Pcnx2	UTSW	8	126,488,481 (GRCm39)	missense	possibly damaging	0.90
R2096:Pcnx2	UTSW	8	126,485,987 (GRCm39)	missense	probably benign	0.27
R2216:Pcnx2	UTSW	8	126,614,816 (GRCm39)	missense	probably benign	0.00
R2290:Pcnx2	UTSW	8	126,604,334 (GRCm39)	splice site	probably benign
R2373:Pcnx2	UTSW	8	126,480,190 (GRCm39)	missense	probably damaging	1.00
R2484:Pcnx2	UTSW	8	126,617,859 (GRCm39)	missense	probably damaging	1.00
R2849:Pcnx2	UTSW	8	126,487,666 (GRCm39)	missense	probably damaging	1.00
R2891:Pcnx2	UTSW	8	126,617,797 (GRCm39)	missense	probably damaging	1.00
R2892:Pcnx2	UTSW	8	126,617,797 (GRCm39)	missense	probably damaging	1.00
R2970:Pcnx2	UTSW	8	126,528,275 (GRCm39)	missense	probably damaging	1.00
R3013:Pcnx2	UTSW	8	126,614,509 (GRCm39)	missense	probably benign	0.05
R3608:Pcnx2	UTSW	8	126,614,840 (GRCm39)	missense	probably benign
R3876:Pcnx2	UTSW	8	126,614,897 (GRCm39)	missense	probably benign
R4349:Pcnx2	UTSW	8	126,489,590 (GRCm39)	missense	probably damaging	0.98
R4352:Pcnx2	UTSW	8	126,489,590 (GRCm39)	missense	probably damaging	0.98
R4353:Pcnx2	UTSW	8	126,489,590 (GRCm39)	missense	probably damaging	0.98
R4361:Pcnx2	UTSW	8	126,495,037 (GRCm39)	nonsense	probably null
R4735:Pcnx2	UTSW	8	126,554,780 (GRCm39)	critical splice donor site	probably null
R4749:Pcnx2	UTSW	8	126,614,327 (GRCm39)	missense	probably damaging	1.00
R4812:Pcnx2	UTSW	8	126,592,678 (GRCm39)	missense	probably benign	0.00
R4819:Pcnx2	UTSW	8	126,581,969 (GRCm39)	missense	probably benign	0.04
R4829:Pcnx2	UTSW	8	126,587,797 (GRCm39)	splice site	probably null
R4832:Pcnx2	UTSW	8	126,478,927 (GRCm39)	missense	probably damaging	0.99
R4876:Pcnx2	UTSW	8	126,498,847 (GRCm39)	missense	probably damaging	1.00
R4974:Pcnx2	UTSW	8	126,577,869 (GRCm39)	missense	probably benign	0.00
R5057:Pcnx2	UTSW	8	126,581,930 (GRCm39)	missense	possibly damaging	0.95
R5078:Pcnx2	UTSW	8	126,478,895 (GRCm39)	missense	probably benign
R5114:Pcnx2	UTSW	8	126,564,749 (GRCm39)	missense	possibly damaging	0.89
R5195:Pcnx2	UTSW	8	126,528,288 (GRCm39)	missense	possibly damaging	0.69
R5239:Pcnx2	UTSW	8	126,587,821 (GRCm39)	splice site	probably null
R5348:Pcnx2	UTSW	8	126,545,495 (GRCm39)	missense	probably damaging	1.00
R5398:Pcnx2	UTSW	8	126,614,687 (GRCm39)	missense	possibly damaging	0.63
R5448:Pcnx2	UTSW	8	126,614,888 (GRCm39)	missense	probably benign	0.14
R5534:Pcnx2	UTSW	8	126,564,754 (GRCm39)	missense	possibly damaging	0.65
R5624:Pcnx2	UTSW	8	126,488,262 (GRCm39)	critical splice donor site	probably null
R5629:Pcnx2	UTSW	8	126,624,780 (GRCm39)	missense	probably damaging	1.00
R5630:Pcnx2	UTSW	8	126,587,697 (GRCm39)	missense	probably damaging	0.99
R5782:Pcnx2	UTSW	8	126,480,223 (GRCm39)	missense	probably damaging	1.00
R5877:Pcnx2	UTSW	8	126,480,467 (GRCm39)	missense	probably damaging	0.99
R5879:Pcnx2	UTSW	8	126,500,685 (GRCm39)	missense	probably damaging	1.00
R6114:Pcnx2	UTSW	8	126,500,686 (GRCm39)	missense	probably damaging	1.00
R6152:Pcnx2	UTSW	8	126,480,491 (GRCm39)	missense	probably damaging	0.99
R6154:Pcnx2	UTSW	8	126,489,552 (GRCm39)	missense	probably damaging	1.00
R6283:Pcnx2	UTSW	8	126,604,325 (GRCm39)	missense	probably damaging	0.99
R6500:Pcnx2	UTSW	8	126,480,224 (GRCm39)	missense	probably damaging	1.00
R6629:Pcnx2	UTSW	8	126,617,851 (GRCm39)	missense	probably benign	0.00
R6708:Pcnx2	UTSW	8	126,587,692 (GRCm39)	critical splice donor site	probably null
R6736:Pcnx2	UTSW	8	126,479,056 (GRCm39)	splice site	probably null
R6748:Pcnx2	UTSW	8	126,577,074 (GRCm39)	missense	probably damaging	1.00
R6788:Pcnx2	UTSW	8	126,498,839 (GRCm39)	missense	probably damaging	1.00
R6849:Pcnx2	UTSW	8	126,587,949 (GRCm39)	missense	probably damaging	1.00
R6947:Pcnx2	UTSW	8	126,577,021 (GRCm39)	critical splice donor site	probably null
R7100:Pcnx2	UTSW	8	126,485,853 (GRCm39)	missense	probably benign	0.16
R7124:Pcnx2	UTSW	8	126,480,356 (GRCm39)	missense	probably damaging	0.99
R7130:Pcnx2	UTSW	8	126,480,323 (GRCm39)	nonsense	probably null
R7133:Pcnx2	UTSW	8	126,528,243 (GRCm39)	missense	probably benign	0.01
R7271:Pcnx2	UTSW	8	126,613,690 (GRCm39)	missense	probably benign
R7326:Pcnx2	UTSW	8	126,613,822 (GRCm39)	missense	probably damaging	1.00
R7373:Pcnx2	UTSW	8	126,534,766 (GRCm39)	missense	probably damaging	1.00
R7397:Pcnx2	UTSW	8	126,617,624 (GRCm39)	splice site	probably null
R7662:Pcnx2	UTSW	8	126,545,510 (GRCm39)	nonsense	probably null
R7693:Pcnx2	UTSW	8	126,613,864 (GRCm39)	missense	probably benign	0.09
R7726:Pcnx2	UTSW	8	126,577,069 (GRCm39)	missense	probably benign	0.00
R7745:Pcnx2	UTSW	8	126,577,846 (GRCm39)	missense	probably benign	0.04
R7792:Pcnx2	UTSW	8	126,618,757 (GRCm39)	missense	possibly damaging	0.63
R7797:Pcnx2	UTSW	8	126,512,087 (GRCm39)	missense	possibly damaging	0.70
R7921:Pcnx2	UTSW	8	126,564,602 (GRCm39)	missense	probably benign
R7984:Pcnx2	UTSW	8	126,485,865 (GRCm39)	missense	probably benign
R8098:Pcnx2	UTSW	8	126,495,040 (GRCm39)	missense	probably damaging	1.00
R8277:Pcnx2	UTSW	8	126,592,755 (GRCm39)	missense	probably damaging	1.00
R8312:Pcnx2	UTSW	8	126,489,589 (GRCm39)	missense	possibly damaging	0.69
R8354:Pcnx2	UTSW	8	126,488,357 (GRCm39)	missense	probably damaging	0.99
R8378:Pcnx2	UTSW	8	126,487,649 (GRCm39)	missense	probably damaging	1.00
R8713:Pcnx2	UTSW	8	126,545,525 (GRCm39)	missense	probably damaging	1.00
R8714:Pcnx2	UTSW	8	126,500,546 (GRCm39)	missense	probably benign
R8753:Pcnx2	UTSW	8	126,613,999 (GRCm39)	missense	probably benign	0.15
R8790:Pcnx2	UTSW	8	126,604,306 (GRCm39)	missense	probably benign
R8925:Pcnx2	UTSW	8	126,614,659 (GRCm39)	missense	probably benign	0.01
R8927:Pcnx2	UTSW	8	126,614,659 (GRCm39)	missense	probably benign	0.01
R8965:Pcnx2	UTSW	8	126,485,853 (GRCm39)	missense	probably benign	0.16
R9006:Pcnx2	UTSW	8	126,613,996 (GRCm39)	missense	probably benign	0.00
R9082:Pcnx2	UTSW	8	126,613,753 (GRCm39)	missense	probably damaging	1.00
R9202:Pcnx2	UTSW	8	126,616,416 (GRCm39)	critical splice acceptor site	probably null
R9315:Pcnx2	UTSW	8	126,614,119 (GRCm39)	missense	probably benign	0.00
R9434:Pcnx2	UTSW	8	126,542,512 (GRCm39)	missense	probably benign	0.00
R9660:Pcnx2	UTSW	8	126,487,592 (GRCm39)	missense	probably damaging	1.00
R9686:Pcnx2	UTSW	8	126,592,766 (GRCm39)	missense	probably benign
R9766:Pcnx2	UTSW	8	126,488,313 (GRCm39)	missense	probably damaging	1.00
R9778:Pcnx2	UTSW	8	126,512,176 (GRCm39)	missense	probably benign	0.00
R9792:Pcnx2	UTSW	8	126,534,820 (GRCm39)	missense	probably damaging	0.99
RF018:Pcnx2	UTSW	8	126,604,258 (GRCm39)	missense	probably damaging	1.00
Z1088:Pcnx2	UTSW	8	126,592,757 (GRCm39)	missense	probably damaging	1.00
Z1088:Pcnx2	UTSW	8	126,553,667 (GRCm39)	missense	probably damaging	1.00
Z1176:Pcnx2	UTSW	8	126,564,753 (GRCm39)	missense	probably benign	0.30
Z1176:Pcnx2	UTSW	8	126,488,393 (GRCm39)	missense	probably damaging	1.00
Z1177:Pcnx2	UTSW	8	126,614,699 (GRCm39)	nonsense	probably null

Predicted Primers

PCR Primer
(F):5'- AACAGTCCCCGAGTCTTTTG -3'
(R):5'- GGGAGTGATGACAACAACCTC -3'

Sequencing Primer
(F):5'- GTCCTCTGCAAGAGTAGTACATGC -3'
(R):5'- GGAGTGATGACAACAACCTCAACTC -3'

Posted On

2019-05-13