Mutagenetix > Incidental Mutation

Incidental Mutation 'R7039:Fcgbpl1'

546944

Institutional Source

Beutler Lab

Gene Symbol

Fcgbpl1

Ensembl Gene

ENSMUSG00000078776

Gene Name

Fc fragment of IgG binding protein like 1

Synonyms

9530053A07Rik

MMRRC Submission

045139-MU

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.103) question?

Stock #

R7039 (G1)

Quality Score

225.009

Status

Not validated

Chromosome

Chromosomal Location

27828891-27864236 bp(+) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

G to A at 27839573 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Arginine to Glutamine at position 462 (R462Q)

Ref Sequence

ENSEMBL: ENSMUSP00000114986 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000059886] [ENSMUST00000150948]

AlphaFold

E9PVG8

Predicted Effect

possibly damaging
Transcript: ENSMUST00000059886
AA Change: R462Q

PolyPhen 2 Score 0.803 (Sensitivity: 0.84; Specificity: 0.93)

SMART Domains

Protein: ENSMUSP00000056479
Gene: ENSMUSG00000078776
AA Change: R462Q

Domain	Start	End	E-Value	Type
low complexity region	8	24	N/A	INTRINSIC
FOLN	27	49	1.23e-4	SMART
VWD	46	211	1.5e-40	SMART
C8	251	326	4.31e-33	SMART
Pfam:TIL	329	383	2e-13	PFAM
VWC	385	448	1.02e0	SMART
VWD	439	603	4.32e-32	SMART
C8	640	715	4.54e-9	SMART
Pfam:TIL	718	771	1.6e-12	PFAM
VWC	773	826	1.1e0	SMART
FOLN	805	827	6.87e1	SMART
VWD	825	988	7.92e-40	SMART
C8	1033	1108	5.1e-35	SMART
Pfam:TIL	1111	1164	7.6e-11	PFAM
VWC	1166	1224	1.1e-2	SMART
FOLN	1197	1219	9.55e-1	SMART
FOLN	1223	1245	5.38e1	SMART
VWD	1241	1410	9.04e-35	SMART
C8	1450	1526	9.54e-26	SMART
low complexity region	1540	1550	N/A	INTRINSIC
EGF_like	1557	1580	5.34e1	SMART
VWC	1588	1681	3.21e-3	SMART
VWD	1639	1806	7.3e-30	SMART
C8	1838	1913	2.44e-32	SMART
EGF_like	1941	1964	4.46e1	SMART
VWC	1971	2062	2.85e-1	SMART
VWD	2022	2178	1.32e-27	SMART
low complexity region	2199	2212	N/A	INTRINSIC
C8	2219	2294	1.43e-29	SMART
Pfam:TIL	2297	2350	1.1e-11	PFAM
FOLN	2383	2405	5.68e1	SMART
VWD	2402	2564	4.58e-4	SMART

Predicted Effect

possibly damaging
Transcript: ENSMUST00000150948
AA Change: R462Q

PolyPhen 2 Score 0.803 (Sensitivity: 0.84; Specificity: 0.93)

SMART Domains

Protein: ENSMUSP00000114986
Gene: ENSMUSG00000078776
AA Change: R462Q

Domain	Start	End	E-Value	Type
low complexity region	8	24	N/A	INTRINSIC
FOLN	27	49	1.23e-4	SMART
VWD	46	211	1.5e-40	SMART
C8	251	326	4.31e-33	SMART
Pfam:TIL	329	383	2e-13	PFAM
VWC	385	448	1.02e0	SMART
VWD	439	603	4.32e-32	SMART
C8	640	715	4.54e-9	SMART
Pfam:TIL	718	771	1.6e-12	PFAM
VWC	773	826	1.1e0	SMART
FOLN	805	827	6.87e1	SMART
VWD	825	988	7.92e-40	SMART
C8	1033	1108	5.1e-35	SMART
Pfam:TIL	1111	1164	7.6e-11	PFAM
VWC	1166	1224	1.1e-2	SMART
FOLN	1197	1219	9.55e-1	SMART
FOLN	1223	1245	5.38e1	SMART
VWD	1241	1410	9.04e-35	SMART
C8	1450	1526	9.54e-26	SMART
low complexity region	1540	1550	N/A	INTRINSIC
EGF_like	1557	1580	5.34e1	SMART
VWC	1588	1681	3.21e-3	SMART
VWD	1639	1806	7.3e-30	SMART
C8	1838	1913	2.44e-32	SMART
EGF_like	1941	1964	4.46e1	SMART
VWC	1971	2062	2.85e-1	SMART
VWD	2022	2178	1.32e-27	SMART
low complexity region	2199	2212	N/A	INTRINSIC
C8	2219	2294	1.43e-29	SMART
Pfam:TIL	2297	2350	1.1e-11	PFAM
FOLN	2383	2405	5.68e1	SMART
VWD	2402	2564	4.58e-4	SMART

Coding Region Coverage

1x: 100.0%
3x: 99.9%
10x: 99.6%
20x: 98.6%

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 72 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Actl7b	A	T	4: 56,741,022 (GRCm39)	L112Q	probably damaging	Het
Agap3	A	C	5: 24,688,399 (GRCm39)	I396L	probably benign	Het
AI987944	G	T	7: 41,023,880 (GRCm39)	S366R	probably benign	Het
Aox3	A	G	1: 58,215,714 (GRCm39)	T1049A	probably damaging	Het
Ap1g2	A	T	14: 55,340,111 (GRCm39)	L407*	probably null	Het
Baiap3	G	A	17: 25,462,814 (GRCm39)	R1075C	probably benign	Het
Brd3	T	C	2: 27,346,929 (GRCm39)	K402E	probably damaging	Het
Cc2d2b	A	T	19: 40,790,845 (GRCm39)	D935V	probably damaging	Het
Cenpe	A	G	3: 134,961,217 (GRCm39)	N1904D	probably benign	Het
Cfap74	G	T	4: 155,538,565 (GRCm39)		probably null	Het
Chrdl2	A	G	7: 99,677,879 (GRCm39)	T261A	probably damaging	Het
Cyp4a14	G	A	4: 115,348,278 (GRCm39)	R400C	probably benign	Het
Dhfr	G	A	13: 92,491,791 (GRCm39)	V9I	probably benign	Het
Epha4	A	G	1: 77,483,422 (GRCm39)	S196P	probably damaging	Het
Evc2	T	A	5: 37,579,232 (GRCm39)	L1115Q	probably damaging	Het
Fat3	T	A	9: 16,287,561 (GRCm39)	E654V	probably damaging	Het
Fer1l4	C	T	2: 155,878,650 (GRCm39)	V14I	probably benign	Het
Frmd5	A	T	2: 121,378,128 (GRCm39)		probably benign	Het
Helz	T	C	11: 107,510,144 (GRCm39)		probably null	Het
Igkv6-13	T	C	6: 70,434,498 (GRCm39)	S116G	probably benign	Het
Iscu	T	C	5: 113,914,833 (GRCm39)	V115A	possibly damaging	Het
Jade2	C	A	11: 51,719,186 (GRCm39)	K253N	probably damaging	Het
Katnal2	A	G	18: 77,134,868 (GRCm39)		probably null	Het
Kif13a	C	T	13: 46,905,931 (GRCm39)	V671M	possibly damaging	Het
Magi3	T	C	3: 103,958,699 (GRCm39)	D462G	probably damaging	Het
Map3k14	T	C	11: 103,111,861 (GRCm39)	N940S	probably damaging	Het
Masp2	A	T	4: 148,687,043 (GRCm39)	M1L	probably benign	Het
Mga	G	A	2: 119,763,159 (GRCm39)	V1272I	probably benign	Het
Mib2	T	C	4: 155,744,158 (GRCm39)	D168G	probably damaging	Het
Mmp1a	TG	TGG	9: 7,465,083 (GRCm38)		probably null	Het
Msto1	A	C	3: 88,818,697 (GRCm39)	V287G	probably damaging	Het
Myo5b	T	A	18: 74,834,599 (GRCm39)	D886E	probably benign	Het
Nek10	T	C	14: 14,826,946 (GRCm38)	I48T	possibly damaging	Het
Nek10	A	T	14: 14,986,700 (GRCm38)	R1013W	probably damaging	Het
Nipsnap3a	T	C	4: 53,000,130 (GRCm39)	V194A	probably damaging	Het
Nlrp9a	A	T	7: 26,267,367 (GRCm39)	T766S	probably benign	Het
Nol10	T	A	12: 17,479,185 (GRCm39)	S672T	possibly damaging	Het
Or4a80	A	T	2: 89,583,095 (GRCm39)	F26I	probably benign	Het
Or4c121	A	T	2: 89,023,790 (GRCm39)	I196N	probably damaging	Het
Or8d1b	T	A	9: 38,887,283 (GRCm39)	F104I	probably damaging	Het
Or8j3c	A	T	2: 86,253,177 (GRCm39)	I281K	possibly damaging	Het
Patj	T	A	4: 98,457,315 (GRCm39)	N1272K	probably damaging	Het
Peak1	T	C	9: 56,165,093 (GRCm39)	E945G	probably benign	Het
Peg3	C	T	7: 6,720,858 (GRCm39)	D16N	probably damaging	Het
Pik3r4	T	G	9: 105,554,089 (GRCm39)	I1082M	possibly damaging	Het
Plekhg5	T	A	4: 152,192,242 (GRCm39)	M472K	possibly damaging	Het
Plekhm1	T	C	11: 103,286,054 (GRCm39)	D127G	probably damaging	Het
Ppfia4	G	A	1: 134,239,853 (GRCm39)	S908L	probably damaging	Het
Psmc3	A	G	2: 90,885,391 (GRCm39)	N60S	probably benign	Het
Rapgef1	T	A	2: 29,616,226 (GRCm39)	D697E	probably damaging	Het
Rapgef3	T	A	15: 97,659,449 (GRCm39)	H54L	probably benign	Het
Rhobtb3	G	A	13: 76,020,572 (GRCm39)	R577*	probably null	Het
Safb2	T	C	17: 56,871,594 (GRCm39)	E218G	possibly damaging	Het
Scaf1	C	T	7: 44,657,850 (GRCm39)	R343H	probably damaging	Het
Snx24	G	A	18: 53,473,307 (GRCm39)		probably null	Het
Tbc1d1	T	C	5: 64,442,100 (GRCm39)	F707L	probably benign	Het
Tcaf2	T	C	6: 42,603,074 (GRCm39)	T829A	probably damaging	Het
Tcea2	C	T	2: 181,328,711 (GRCm39)	Q248*	probably null	Het
Tcirg1	A	T	19: 3,946,666 (GRCm39)	L729Q	probably damaging	Het
Thap3	A	G	4: 152,070,149 (GRCm39)	F82L	probably damaging	Het
Ttk	T	A	9: 83,750,145 (GRCm39)	M700K	probably damaging	Het
Ubap2l	G	T	3: 89,909,662 (GRCm39)	P56H	probably damaging	Het
Ubr2	A	G	17: 47,321,139 (GRCm39)	S3P	probably benign	Het
Uchl3	C	T	14: 101,923,128 (GRCm39)		probably benign	Het
Vmn2r111	T	A	17: 22,767,165 (GRCm39)	E777D	probably damaging	Het
Vmn2r20	A	T	6: 123,363,082 (GRCm39)	D567E	probably damaging	Het
Vps13c	T	G	9: 67,845,045 (GRCm39)	L2043R	probably damaging	Het
Zan	T	G	5: 137,398,396 (GRCm39)	D4212A	unknown	Het
Zap70	C	T	1: 36,817,832 (GRCm39)	P278S	probably benign	Het
Zbtb8b	A	T	4: 129,321,478 (GRCm39)	M461K	possibly damaging	Het
Zfat	T	G	15: 68,052,211 (GRCm39)	I528L	probably benign	Het
Zfp532	T	G	18: 65,771,834 (GRCm39)	V784G	probably benign	Het

Other mutations in Fcgbpl1

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00435:Fcgbpl1	APN	7	27,863,953 (GRCm39)	missense	probably damaging	1.00
IGL00757:Fcgbpl1	APN	7	27,853,870 (GRCm39)	missense	probably damaging	1.00
IGL01015:Fcgbpl1	APN	7	27,854,743 (GRCm39)	missense	probably damaging	1.00
IGL01079:Fcgbpl1	APN	7	27,839,203 (GRCm39)	missense	probably damaging	0.99
IGL01343:Fcgbpl1	APN	7	27,850,127 (GRCm39)	missense	probably benign	0.19
IGL01420:Fcgbpl1	APN	7	27,839,558 (GRCm39)	missense	probably benign	0.28
IGL01604:Fcgbpl1	APN	7	27,854,749 (GRCm39)	missense	probably benign	0.11
IGL01666:Fcgbpl1	APN	7	27,852,717 (GRCm39)	missense	probably damaging	1.00
IGL02002:Fcgbpl1	APN	7	27,852,221 (GRCm39)	missense	probably damaging	1.00
IGL02036:Fcgbpl1	APN	7	27,836,950 (GRCm39)	missense	possibly damaging	0.82
IGL02126:Fcgbpl1	APN	7	27,839,281 (GRCm39)	missense	probably damaging	1.00
IGL02150:Fcgbpl1	APN	7	27,846,204 (GRCm39)	nonsense	probably null
IGL02219:Fcgbpl1	APN	7	27,854,060 (GRCm39)	missense	probably damaging	1.00
IGL02563:Fcgbpl1	APN	7	27,857,317 (GRCm39)	missense	probably benign
IGL02804:Fcgbpl1	APN	7	27,852,795 (GRCm39)	missense	probably benign	0.00
IGL02830:Fcgbpl1	APN	7	27,862,348 (GRCm39)	missense	probably damaging	1.00
IGL02943:Fcgbpl1	APN	7	27,846,613 (GRCm39)	missense	probably damaging	1.00
IGL02977:Fcgbpl1	APN	7	27,863,797 (GRCm39)	missense	possibly damaging	0.83
IGL03231:Fcgbpl1	APN	7	27,853,147 (GRCm39)	missense	possibly damaging	0.95
IGL03304:Fcgbpl1	APN	7	27,841,667 (GRCm39)	missense	probably damaging	0.99
herz	UTSW	7	27,853,264 (GRCm39)	missense	possibly damaging	0.72
pulse	UTSW	7	27,853,174 (GRCm39)	missense	probably damaging	1.00
Sinusoidal	UTSW	7	27,839,555 (GRCm39)	missense	probably damaging	1.00
PIT4378001:Fcgbpl1	UTSW	7	27,853,889 (GRCm39)	missense	possibly damaging	0.61
R0023:Fcgbpl1	UTSW	7	27,852,837 (GRCm39)	missense	probably benign	0.00
R0131:Fcgbpl1	UTSW	7	27,837,040 (GRCm39)	missense	probably damaging	1.00
R0131:Fcgbpl1	UTSW	7	27,837,040 (GRCm39)	missense	probably damaging	1.00
R0132:Fcgbpl1	UTSW	7	27,837,040 (GRCm39)	missense	probably damaging	1.00
R0158:Fcgbpl1	UTSW	7	27,854,917 (GRCm39)	missense	probably damaging	1.00
R0230:Fcgbpl1	UTSW	7	27,856,250 (GRCm39)	missense	probably damaging	1.00
R0310:Fcgbpl1	UTSW	7	27,841,699 (GRCm39)	missense	probably benign	0.04
R0448:Fcgbpl1	UTSW	7	27,839,660 (GRCm39)	missense	probably benign	0.03
R0462:Fcgbpl1	UTSW	7	27,836,765 (GRCm39)	missense	probably damaging	1.00
R0481:Fcgbpl1	UTSW	7	27,853,174 (GRCm39)	missense	probably damaging	1.00
R0497:Fcgbpl1	UTSW	7	27,846,890 (GRCm39)	missense	probably damaging	1.00
R0556:Fcgbpl1	UTSW	7	27,858,803 (GRCm39)	missense	probably benign
R0562:Fcgbpl1	UTSW	7	27,862,115 (GRCm39)	missense	probably benign	0.30
R0586:Fcgbpl1	UTSW	7	27,836,516 (GRCm39)	missense	probably damaging	0.99
R0924:Fcgbpl1	UTSW	7	27,839,555 (GRCm39)	missense	probably damaging	1.00
R0930:Fcgbpl1	UTSW	7	27,839,555 (GRCm39)	missense	probably damaging	1.00
R1103:Fcgbpl1	UTSW	7	27,853,945 (GRCm39)	missense	probably damaging	1.00
R1213:Fcgbpl1	UTSW	7	27,857,098 (GRCm39)	missense	probably damaging	1.00
R1292:Fcgbpl1	UTSW	7	27,842,219 (GRCm39)	splice site	probably benign
R1368:Fcgbpl1	UTSW	7	27,858,903 (GRCm39)	missense	possibly damaging	0.89
R1451:Fcgbpl1	UTSW	7	27,836,582 (GRCm39)	missense	probably damaging	1.00
R1477:Fcgbpl1	UTSW	7	27,856,518 (GRCm39)	missense	probably benign	0.01
R1538:Fcgbpl1	UTSW	7	27,854,917 (GRCm39)	missense	probably damaging	1.00
R1655:Fcgbpl1	UTSW	7	27,846,535 (GRCm39)	missense	probably damaging	0.98
R1697:Fcgbpl1	UTSW	7	27,853,772 (GRCm39)	missense	probably damaging	1.00
R1741:Fcgbpl1	UTSW	7	27,857,279 (GRCm39)	missense	probably damaging	0.98
R1796:Fcgbpl1	UTSW	7	27,854,797 (GRCm39)	missense	probably damaging	1.00
R1853:Fcgbpl1	UTSW	7	27,854,971 (GRCm39)	nonsense	probably null
R1861:Fcgbpl1	UTSW	7	27,854,157 (GRCm39)	missense	probably damaging	1.00
R1909:Fcgbpl1	UTSW	7	27,843,773 (GRCm39)	missense	possibly damaging	0.52
R1971:Fcgbpl1	UTSW	7	27,830,937 (GRCm39)	missense	possibly damaging	0.90
R1990:Fcgbpl1	UTSW	7	27,853,785 (GRCm39)	missense	probably damaging	0.98
R2020:Fcgbpl1	UTSW	7	27,855,019 (GRCm39)	missense	probably benign
R2084:Fcgbpl1	UTSW	7	27,856,960 (GRCm39)	missense	probably damaging	1.00
R2125:Fcgbpl1	UTSW	7	27,857,447 (GRCm39)	missense	probably benign	0.00
R2132:Fcgbpl1	UTSW	7	27,854,899 (GRCm39)	missense	probably damaging	1.00
R2513:Fcgbpl1	UTSW	7	27,831,060 (GRCm39)	missense	probably damaging	0.99
R2913:Fcgbpl1	UTSW	7	27,863,732 (GRCm39)	missense	probably damaging	1.00
R3150:Fcgbpl1	UTSW	7	27,853,620 (GRCm39)	missense	probably benign	0.21
R3499:Fcgbpl1	UTSW	7	27,853,980 (GRCm39)	missense	probably benign	0.42
R3702:Fcgbpl1	UTSW	7	27,857,203 (GRCm39)	missense	probably damaging	1.00
R3881:Fcgbpl1	UTSW	7	27,839,463 (GRCm39)	nonsense	probably null
R3938:Fcgbpl1	UTSW	7	27,853,719 (GRCm39)	missense	probably damaging	1.00
R4050:Fcgbpl1	UTSW	7	27,852,410 (GRCm39)	missense	possibly damaging	0.55
R4152:Fcgbpl1	UTSW	7	27,856,322 (GRCm39)	missense	possibly damaging	0.47
R4168:Fcgbpl1	UTSW	7	27,836,534 (GRCm39)	missense	probably benign	0.05
R4235:Fcgbpl1	UTSW	7	27,856,073 (GRCm39)	missense	probably damaging	0.99
R4241:Fcgbpl1	UTSW	7	27,853,760 (GRCm39)	missense	probably damaging	1.00
R4363:Fcgbpl1	UTSW	7	27,846,331 (GRCm39)	missense	probably damaging	1.00
R4460:Fcgbpl1	UTSW	7	27,852,281 (GRCm39)	missense	probably benign	0.17
R4463:Fcgbpl1	UTSW	7	27,850,144 (GRCm39)	missense	probably benign
R4841:Fcgbpl1	UTSW	7	27,850,147 (GRCm39)	missense	probably damaging	1.00
R4842:Fcgbpl1	UTSW	7	27,850,147 (GRCm39)	missense	probably damaging	1.00
R4876:Fcgbpl1	UTSW	7	27,842,225 (GRCm39)	intron	probably benign
R4905:Fcgbpl1	UTSW	7	27,856,408 (GRCm39)	missense	possibly damaging	0.93
R4997:Fcgbpl1	UTSW	7	27,843,349 (GRCm39)	missense	possibly damaging	0.77
R5091:Fcgbpl1	UTSW	7	27,856,383 (GRCm39)	missense	probably benign	0.44
R5159:Fcgbpl1	UTSW	7	27,852,733 (GRCm39)	missense	probably benign	0.09
R5326:Fcgbpl1	UTSW	7	27,854,914 (GRCm39)	missense	probably damaging	0.98
R5396:Fcgbpl1	UTSW	7	27,839,608 (GRCm39)	missense	probably benign
R5441:Fcgbpl1	UTSW	7	27,856,339 (GRCm39)	missense	probably damaging	1.00
R5480:Fcgbpl1	UTSW	7	27,857,424 (GRCm39)	nonsense	probably null
R5542:Fcgbpl1	UTSW	7	27,854,914 (GRCm39)	missense	probably damaging	0.98
R5571:Fcgbpl1	UTSW	7	27,855,994 (GRCm39)	missense	probably damaging	0.99
R5613:Fcgbpl1	UTSW	7	27,842,303 (GRCm39)	intron	probably benign
R5637:Fcgbpl1	UTSW	7	27,852,277 (GRCm39)	missense	probably benign	0.00
R5766:Fcgbpl1	UTSW	7	27,836,754 (GRCm39)	nonsense	probably null
R6174:Fcgbpl1	UTSW	7	27,839,384 (GRCm39)	missense	probably damaging	0.96
R6233:Fcgbpl1	UTSW	7	27,830,885 (GRCm39)	missense	probably damaging	0.99
R6250:Fcgbpl1	UTSW	7	27,850,139 (GRCm39)	missense	probably damaging	1.00
R6379:Fcgbpl1	UTSW	7	27,857,017 (GRCm39)	missense	probably damaging	1.00
R6442:Fcgbpl1	UTSW	7	27,843,611 (GRCm39)	missense	possibly damaging	0.88
R6478:Fcgbpl1	UTSW	7	27,854,798 (GRCm39)	missense	probably damaging	1.00
R6699:Fcgbpl1	UTSW	7	27,843,793 (GRCm39)	missense	probably damaging	1.00
R6852:Fcgbpl1	UTSW	7	27,846,560 (GRCm39)	missense	probably damaging	1.00
R6883:Fcgbpl1	UTSW	7	27,852,260 (GRCm39)	missense	possibly damaging	0.89
R6902:Fcgbpl1	UTSW	7	27,836,638 (GRCm39)	missense	probably damaging	1.00
R6903:Fcgbpl1	UTSW	7	27,836,638 (GRCm39)	missense	probably damaging	1.00
R6904:Fcgbpl1	UTSW	7	27,836,638 (GRCm39)	missense	probably damaging	1.00
R6992:Fcgbpl1	UTSW	7	27,839,608 (GRCm39)	missense	probably benign	0.04
R7023:Fcgbpl1	UTSW	7	27,839,463 (GRCm39)	nonsense	probably null
R7171:Fcgbpl1	UTSW	7	27,853,944 (GRCm39)	nonsense	probably null
R7282:Fcgbpl1	UTSW	7	27,843,833 (GRCm39)	missense	probably benign	0.02
R7291:Fcgbpl1	UTSW	7	27,839,645 (GRCm39)	missense	probably benign
R7344:Fcgbpl1	UTSW	7	27,852,185 (GRCm39)	missense	possibly damaging	0.46
R7344:Fcgbpl1	UTSW	7	27,839,704 (GRCm39)	missense	possibly damaging	0.79
R7392:Fcgbpl1	UTSW	7	27,863,797 (GRCm39)	missense	possibly damaging	0.83
R7531:Fcgbpl1	UTSW	7	27,839,656 (GRCm39)	missense	probably benign
R7541:Fcgbpl1	UTSW	7	27,843,681 (GRCm39)	nonsense	probably null
R7577:Fcgbpl1	UTSW	7	27,853,848 (GRCm39)	missense	possibly damaging	0.65
R7594:Fcgbpl1	UTSW	7	27,830,885 (GRCm39)	missense	probably damaging	0.99
R7647:Fcgbpl1	UTSW	7	27,839,470 (GRCm39)	missense	probably benign	0.00
R7718:Fcgbpl1	UTSW	7	27,846,626 (GRCm39)	missense	probably damaging	1.00
R7733:Fcgbpl1	UTSW	7	27,839,390 (GRCm39)	missense	probably damaging	1.00
R7737:Fcgbpl1	UTSW	7	27,856,498 (GRCm39)	missense	probably damaging	1.00
R7908:Fcgbpl1	UTSW	7	27,846,921 (GRCm39)	missense	probably benign	0.12
R8013:Fcgbpl1	UTSW	7	27,836,966 (GRCm39)	missense	probably benign	0.14
R8014:Fcgbpl1	UTSW	7	27,836,966 (GRCm39)	missense	probably benign	0.14
R8151:Fcgbpl1	UTSW	7	27,852,766 (GRCm39)	missense	possibly damaging	0.95
R8175:Fcgbpl1	UTSW	7	27,863,873 (GRCm39)	nonsense	probably null
R8254:Fcgbpl1	UTSW	7	27,846,774 (GRCm39)	missense	possibly damaging	0.63
R8345:Fcgbpl1	UTSW	7	27,854,785 (GRCm39)	missense	probably damaging	1.00
R8414:Fcgbpl1	UTSW	7	27,842,158 (GRCm39)	missense	probably damaging	1.00
R8419:Fcgbpl1	UTSW	7	27,843,346 (GRCm39)	missense	probably damaging	1.00
R8496:Fcgbpl1	UTSW	7	27,843,377 (GRCm39)	missense	possibly damaging	0.81
R8691:Fcgbpl1	UTSW	7	27,853,264 (GRCm39)	missense	possibly damaging	0.72
R8785:Fcgbpl1	UTSW	7	27,854,132 (GRCm39)	missense	probably damaging	1.00
R8863:Fcgbpl1	UTSW	7	27,831,006 (GRCm39)	missense	probably damaging	1.00
R8926:Fcgbpl1	UTSW	7	27,853,869 (GRCm39)	missense	probably damaging	1.00
R8950:Fcgbpl1	UTSW	7	27,863,751 (GRCm39)	missense	probably benign	0.32
R9014:Fcgbpl1	UTSW	7	27,854,876 (GRCm39)	missense	probably damaging	1.00
R9045:Fcgbpl1	UTSW	7	27,853,856 (GRCm39)	missense	probably damaging	1.00
R9115:Fcgbpl1	UTSW	7	27,853,754 (GRCm39)	missense	possibly damaging	0.74
R9233:Fcgbpl1	UTSW	7	27,839,519 (GRCm39)	missense	possibly damaging	0.83
R9330:Fcgbpl1	UTSW	7	27,856,410 (GRCm39)	missense	probably benign	0.02
R9426:Fcgbpl1	UTSW	7	27,843,281 (GRCm39)	missense	possibly damaging	0.92
R9477:Fcgbpl1	UTSW	7	27,852,265 (GRCm39)	missense	probably damaging	1.00
R9502:Fcgbpl1	UTSW	7	27,836,891 (GRCm39)	missense	probably benign	0.09
R9505:Fcgbpl1	UTSW	7	27,841,909 (GRCm39)	nonsense	probably null
R9601:Fcgbpl1	UTSW	7	27,853,805 (GRCm39)	missense	possibly damaging	0.78
R9630:Fcgbpl1	UTSW	7	27,836,624 (GRCm39)	missense	probably damaging	1.00
R9632:Fcgbpl1	UTSW	7	27,841,726 (GRCm39)	missense	probably benign
R9673:Fcgbpl1	UTSW	7	27,856,044 (GRCm39)	missense	probably benign	0.25
R9735:Fcgbpl1	UTSW	7	27,856,435 (GRCm39)	missense	probably damaging	1.00
Z1176:Fcgbpl1	UTSW	7	27,854,187 (GRCm39)	missense	probably benign	0.03
Z1176:Fcgbpl1	UTSW	7	27,841,811 (GRCm39)	missense	probably benign	0.06
Z1177:Fcgbpl1	UTSW	7	27,839,323 (GRCm39)	missense	probably benign	0.25
Z1186:Fcgbpl1	UTSW	7	27,856,411 (GRCm39)	missense	probably benign	0.01
Z1186:Fcgbpl1	UTSW	7	27,846,130 (GRCm39)	missense	probably benign	0.00
Z1186:Fcgbpl1	UTSW	7	27,830,997 (GRCm39)	missense	probably benign

Predicted Primers

PCR Primer
(F):5'- CCCCAGGTCAAGAAGTGTAC -3'
(R):5'- TCACCAGCACTTTGCCTTGG -3'

Sequencing Primer
(F):5'- TGTACGCGGACGAAAAATGCC -3'
(R):5'- TTGGTATTCCCGGCGCAC -3'

Posted On

2019-05-13