Incidental Mutation 'R7058:Zdbf2'
| ID |
548023 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Zdbf2
|
| Ensembl Gene |
ENSMUSG00000027520 |
| Gene Name |
zinc finger, DBF-type containing 2 |
| Synonyms |
4930431J08Rik, 9330107J05Rik |
| MMRRC Submission |
045155-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.119)
|
| Stock # |
R7058 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
1 |
| Chromosomal Location |
63312424-63353735 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to A
at 63346563 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Histidine to Glutamine
at position 1647
(H1647Q)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000109767
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000029025]
[ENSMUST00000114132]
|
| AlphaFold |
Q5SS00 |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000029025
AA Change: H1647Q
PolyPhen 2
Score 0.663 (Sensitivity: 0.86; Specificity: 0.91)
|
| SMART Domains |
Protein: ENSMUSP00000029025
Gene: ENSMUSG00000027520
AA Change: H1647Q
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
79 |
99 |
N/A |
INTRINSIC |
|
low complexity region
|
150 |
164 |
N/A |
INTRINSIC |
|
low complexity region
|
378 |
405 |
N/A |
INTRINSIC |
|
internal_repeat_6
|
407 |
565 |
7.68e-5 |
PROSPERO |
|
internal_repeat_5
|
418 |
768 |
5.53e-5 |
PROSPERO |
|
internal_repeat_1
|
618 |
873 |
3.17e-15 |
PROSPERO |
|
internal_repeat_4
|
621 |
885 |
2.09e-6 |
PROSPERO |
|
internal_repeat_3
|
642 |
886 |
1.52e-7 |
PROSPERO |
|
internal_repeat_2
|
650 |
912 |
5.87e-11 |
PROSPERO |
|
internal_repeat_6
|
722 |
891 |
7.68e-5 |
PROSPERO |
|
low complexity region
|
965 |
982 |
N/A |
INTRINSIC |
|
internal_repeat_4
|
1061 |
1328 |
2.09e-6 |
PROSPERO |
|
internal_repeat_2
|
1215 |
1484 |
5.87e-11 |
PROSPERO |
|
internal_repeat_3
|
1287 |
1507 |
1.52e-7 |
PROSPERO |
|
internal_repeat_1
|
1307 |
1536 |
3.17e-15 |
PROSPERO |
|
internal_repeat_5
|
1388 |
1758 |
5.53e-5 |
PROSPERO |
|
low complexity region
|
1767 |
1778 |
N/A |
INTRINSIC |
|
low complexity region
|
2211 |
2235 |
N/A |
INTRINSIC |
|
low complexity region
|
2240 |
2399 |
N/A |
INTRINSIC |
|
low complexity region
|
2402 |
2420 |
N/A |
INTRINSIC |
|
low complexity region
|
2446 |
2458 |
N/A |
INTRINSIC |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000114132
AA Change: H1647Q
PolyPhen 2
Score 0.663 (Sensitivity: 0.86; Specificity: 0.91)
|
| SMART Domains |
Protein: ENSMUSP00000109767
Gene: ENSMUSG00000027520
AA Change: H1647Q
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
79 |
99 |
N/A |
INTRINSIC |
|
low complexity region
|
150 |
164 |
N/A |
INTRINSIC |
|
low complexity region
|
378 |
405 |
N/A |
INTRINSIC |
|
internal_repeat_6
|
407 |
565 |
7.68e-5 |
PROSPERO |
|
internal_repeat_5
|
418 |
768 |
5.53e-5 |
PROSPERO |
|
internal_repeat_1
|
618 |
873 |
3.17e-15 |
PROSPERO |
|
internal_repeat_4
|
621 |
885 |
2.09e-6 |
PROSPERO |
|
internal_repeat_3
|
642 |
886 |
1.52e-7 |
PROSPERO |
|
internal_repeat_2
|
650 |
912 |
5.87e-11 |
PROSPERO |
|
internal_repeat_6
|
722 |
891 |
7.68e-5 |
PROSPERO |
|
low complexity region
|
965 |
982 |
N/A |
INTRINSIC |
|
internal_repeat_4
|
1061 |
1328 |
2.09e-6 |
PROSPERO |
|
internal_repeat_2
|
1215 |
1484 |
5.87e-11 |
PROSPERO |
|
internal_repeat_3
|
1287 |
1507 |
1.52e-7 |
PROSPERO |
|
internal_repeat_1
|
1307 |
1536 |
3.17e-15 |
PROSPERO |
|
internal_repeat_5
|
1388 |
1758 |
5.53e-5 |
PROSPERO |
|
low complexity region
|
1767 |
1778 |
N/A |
INTRINSIC |
|
low complexity region
|
2211 |
2235 |
N/A |
INTRINSIC |
|
low complexity region
|
2240 |
2399 |
N/A |
INTRINSIC |
|
low complexity region
|
2402 |
2420 |
N/A |
INTRINSIC |
|
low complexity region
|
2446 |
2458 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 100.0%
- 10x: 99.7%
- 20x: 99.0%
|
| Validation Efficiency |
100% (87/87) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a protein containing DBF4-type zinc finger domains. This gene is imprinted and paternally expressed in lymphocytes but is more stochastically expressed in the placenta. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2015]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 87 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 2610021A01Rik |
T |
C |
7: 41,275,554 (GRCm39) |
I419T |
possibly damaging |
Het |
| Afap1 |
T |
C |
5: 36,119,604 (GRCm39) |
V294A |
probably benign |
Het |
| Amotl1 |
T |
A |
9: 14,486,532 (GRCm39) |
Q454L |
possibly damaging |
Het |
| Ap2a1 |
T |
C |
7: 44,550,215 (GRCm39) |
S961G |
probably damaging |
Het |
| Asxl3 |
A |
G |
18: 22,650,731 (GRCm39) |
K907E |
probably damaging |
Het |
| BC028528 |
A |
T |
3: 95,792,323 (GRCm39) |
L137I |
possibly damaging |
Het |
| Cand1 |
A |
T |
10: 119,047,659 (GRCm39) |
N610K |
probably benign |
Het |
| Cat |
A |
G |
2: 103,304,698 (GRCm39) |
I109T |
probably benign |
Het |
| Ccdc18 |
T |
C |
5: 108,341,664 (GRCm39) |
V853A |
probably benign |
Het |
| Chd4 |
C |
A |
6: 125,085,405 (GRCm39) |
D805E |
possibly damaging |
Het |
| Cnih1 |
A |
C |
14: 47,017,652 (GRCm39) |
F77V |
probably damaging |
Het |
| Cntd1 |
A |
T |
11: 101,178,252 (GRCm39) |
I284F |
probably damaging |
Het |
| Col6a3 |
C |
A |
1: 90,755,759 (GRCm39) |
E177* |
probably null |
Het |
| Cpxm2 |
T |
A |
7: 131,745,408 (GRCm39) |
D139V |
probably benign |
Het |
| Cyp1a2 |
G |
T |
9: 57,584,525 (GRCm39) |
R510S |
probably damaging |
Het |
| D2hgdh |
T |
C |
1: 93,763,096 (GRCm39) |
S294P |
probably damaging |
Het |
| Dchs1 |
A |
G |
7: 105,406,228 (GRCm39) |
C2335R |
probably benign |
Het |
| Disc1 |
G |
T |
8: 125,977,724 (GRCm39) |
C719F |
probably damaging |
Het |
| Dnah14 |
A |
C |
1: 181,525,614 (GRCm39) |
D2180A |
probably benign |
Het |
| Dop1b |
G |
A |
16: 93,573,878 (GRCm39) |
R1582Q |
probably benign |
Het |
| Dsg2 |
A |
T |
18: 20,725,332 (GRCm39) |
H481L |
probably benign |
Het |
| Epha6 |
A |
G |
16: 59,503,013 (GRCm39) |
S965P |
probably damaging |
Het |
| Esrrg |
G |
T |
1: 187,882,503 (GRCm39) |
L253F |
probably damaging |
Het |
| Exoc6b |
T |
C |
6: 84,831,704 (GRCm39) |
K438R |
probably damaging |
Het |
| Fam98a |
C |
A |
17: 75,845,384 (GRCm39) |
R454L |
unknown |
Het |
| Fam98c |
A |
T |
7: 28,855,308 (GRCm39) |
|
probably null |
Het |
| Fhad1 |
CGG |
CG |
4: 141,645,602 (GRCm39) |
|
probably null |
Het |
| Galnt13 |
A |
G |
2: 54,988,587 (GRCm39) |
T470A |
probably damaging |
Het |
| Ggt7 |
A |
T |
2: 155,345,015 (GRCm39) |
|
probably null |
Het |
| Golim4 |
T |
C |
3: 75,785,957 (GRCm39) |
E606G |
probably damaging |
Het |
| Gpd2 |
G |
A |
2: 57,197,112 (GRCm39) |
|
probably null |
Het |
| Grin2b |
T |
C |
6: 135,757,304 (GRCm39) |
M386V |
probably damaging |
Het |
| Hfm1 |
A |
T |
5: 107,059,306 (GRCm39) |
S239T |
probably benign |
Het |
| Hmcn1 |
G |
A |
1: 150,649,641 (GRCm39) |
T615I |
probably benign |
Het |
| Hook2 |
G |
A |
8: 85,724,040 (GRCm39) |
E446K |
possibly damaging |
Het |
| Hsd3b1 |
C |
T |
3: 98,765,131 (GRCm39) |
|
probably null |
Het |
| Igsf9b |
A |
G |
9: 27,234,150 (GRCm39) |
Y421C |
probably damaging |
Het |
| Il21 |
A |
G |
3: 37,286,629 (GRCm39) |
L29P |
probably damaging |
Het |
| Ildr1 |
A |
G |
16: 36,542,730 (GRCm39) |
S421G |
probably benign |
Het |
| Kat2b |
C |
A |
17: 53,972,894 (GRCm39) |
T736K |
probably benign |
Het |
| Kcng1 |
A |
G |
2: 168,104,529 (GRCm39) |
V439A |
probably damaging |
Het |
| Kif21a |
A |
T |
15: 90,833,106 (GRCm39) |
|
probably null |
Het |
| Lat |
A |
G |
7: 125,968,318 (GRCm39) |
|
probably null |
Het |
| Mastl |
T |
A |
2: 23,023,425 (GRCm39) |
K433* |
probably null |
Het |
| Mettl2 |
A |
G |
11: 105,019,719 (GRCm39) |
R119G |
probably benign |
Het |
| Mia2 |
C |
T |
12: 59,231,021 (GRCm39) |
P1223L |
possibly damaging |
Het |
| Mkrn2os |
G |
T |
6: 115,563,635 (GRCm39) |
D133E |
probably benign |
Het |
| Mslnl |
A |
G |
17: 25,962,186 (GRCm39) |
T195A |
probably benign |
Het |
| Muc16 |
T |
G |
9: 18,551,051 (GRCm39) |
T5081P |
probably benign |
Het |
| Mylpf |
G |
C |
7: 126,813,139 (GRCm39) |
R110P |
probably damaging |
Het |
| Myo19 |
G |
T |
11: 84,798,194 (GRCm39) |
C738F |
possibly damaging |
Het |
| Nat8f4 |
T |
A |
6: 85,878,271 (GRCm39) |
N84I |
possibly damaging |
Het |
| Nol8 |
C |
T |
13: 49,829,862 (GRCm39) |
R1104C |
probably damaging |
Het |
| Notch1 |
A |
T |
2: 26,353,830 (GRCm39) |
D1932E |
probably benign |
Het |
| Nsun3 |
A |
T |
16: 62,596,663 (GRCm39) |
C152S |
possibly damaging |
Het |
| Opcml |
G |
A |
9: 28,586,507 (GRCm39) |
W75* |
probably null |
Het |
| Or14j10 |
A |
G |
17: 37,934,597 (GRCm39) |
F310L |
probably benign |
Het |
| Pcdh7 |
G |
A |
5: 57,879,582 (GRCm39) |
E1046K |
probably damaging |
Het |
| Pcdhb9 |
T |
A |
18: 37,536,334 (GRCm39) |
V776D |
probably benign |
Het |
| Pla2g4a |
A |
G |
1: 149,727,103 (GRCm39) |
L551S |
probably damaging |
Het |
| Plaa |
G |
A |
4: 94,458,060 (GRCm39) |
Q637* |
probably null |
Het |
| Plekhh1 |
A |
T |
12: 79,122,204 (GRCm39) |
E1099V |
probably damaging |
Het |
| Ppp4r1 |
A |
T |
17: 66,136,495 (GRCm39) |
N551Y |
probably benign |
Het |
| R3hdm2 |
T |
C |
10: 127,320,382 (GRCm39) |
V554A |
probably damaging |
Het |
| Rab44 |
A |
G |
17: 29,357,150 (GRCm39) |
|
probably null |
Het |
| Rab5c |
G |
A |
11: 100,610,789 (GRCm39) |
R40C |
probably damaging |
Het |
| Rasgrf2 |
T |
C |
13: 92,034,521 (GRCm39) |
T1119A |
probably damaging |
Het |
| Rims2 |
A |
G |
15: 39,449,044 (GRCm39) |
D1194G |
probably damaging |
Het |
| Scarb1 |
A |
T |
5: 125,374,294 (GRCm39) |
C280S |
probably damaging |
Het |
| Sde2 |
T |
C |
1: 180,693,827 (GRCm39) |
F439S |
probably damaging |
Het |
| Setd5 |
T |
C |
6: 113,092,532 (GRCm39) |
I304T |
probably benign |
Het |
| Sipa1l1 |
A |
G |
12: 82,449,896 (GRCm39) |
E1106G |
probably benign |
Het |
| Sis |
T |
G |
3: 72,810,940 (GRCm39) |
S1694R |
probably damaging |
Het |
| Smad9 |
T |
A |
3: 54,693,614 (GRCm39) |
F181Y |
probably benign |
Het |
| Smg1 |
A |
G |
7: 117,797,502 (GRCm39) |
|
probably benign |
Het |
| Sspo |
T |
C |
6: 48,425,516 (GRCm39) |
Y46H |
probably damaging |
Het |
| Tdrd12 |
A |
G |
7: 35,177,534 (GRCm39) |
M940T |
unknown |
Het |
| Tmem44 |
G |
T |
16: 30,366,213 (GRCm39) |
T71K |
possibly damaging |
Het |
| Tmf1 |
T |
A |
6: 97,133,911 (GRCm39) |
E1009V |
probably damaging |
Het |
| Ttc39a |
C |
T |
4: 109,288,763 (GRCm39) |
R288W |
probably damaging |
Het |
| Ttc9c |
G |
A |
19: 8,796,191 (GRCm39) |
|
probably benign |
Het |
| Usp28 |
T |
A |
9: 48,950,456 (GRCm39) |
Y634N |
probably damaging |
Het |
| Vmn1r211 |
C |
T |
13: 23,036,063 (GRCm39) |
M201I |
probably benign |
Het |
| Vmn2r54 |
T |
A |
7: 12,349,722 (GRCm39) |
Q620L |
possibly damaging |
Het |
| Vps13c |
T |
C |
9: 67,831,110 (GRCm39) |
L1580P |
probably benign |
Het |
| Vrk3 |
C |
A |
7: 44,417,890 (GRCm39) |
F308L |
probably damaging |
Het |
| Zfp984 |
A |
T |
4: 147,840,002 (GRCm39) |
M283K |
probably benign |
Het |
|
| Other mutations in Zdbf2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00790:Zdbf2
|
APN |
1 |
63,345,673 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
IGL00796:Zdbf2
|
APN |
1 |
63,346,364 (GRCm39) |
missense |
probably benign |
0.04 |
|
IGL00801:Zdbf2
|
APN |
1 |
63,342,197 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
IGL02803:Zdbf2
|
APN |
1 |
63,342,236 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R0143:Zdbf2
|
UTSW |
1 |
63,347,233 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0147:Zdbf2
|
UTSW |
1 |
63,343,165 (GRCm39) |
nonsense |
probably null |
|
|
R0148:Zdbf2
|
UTSW |
1 |
63,343,165 (GRCm39) |
nonsense |
probably null |
|
|
R0433:Zdbf2
|
UTSW |
1 |
63,345,302 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R0502:Zdbf2
|
UTSW |
1 |
63,344,449 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R0645:Zdbf2
|
UTSW |
1 |
63,344,109 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R0765:Zdbf2
|
UTSW |
1 |
63,344,882 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R1068:Zdbf2
|
UTSW |
1 |
63,342,589 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R1216:Zdbf2
|
UTSW |
1 |
63,342,161 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R1235:Zdbf2
|
UTSW |
1 |
63,348,232 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R1352:Zdbf2
|
UTSW |
1 |
63,342,212 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R1402:Zdbf2
|
UTSW |
1 |
63,342,786 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R1402:Zdbf2
|
UTSW |
1 |
63,342,786 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R1435:Zdbf2
|
UTSW |
1 |
63,342,199 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R1562:Zdbf2
|
UTSW |
1 |
63,342,747 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R1624:Zdbf2
|
UTSW |
1 |
63,343,018 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R1635:Zdbf2
|
UTSW |
1 |
63,343,493 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R1644:Zdbf2
|
UTSW |
1 |
63,348,131 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R1662:Zdbf2
|
UTSW |
1 |
63,343,408 (GRCm39) |
nonsense |
probably null |
|
|
R1700:Zdbf2
|
UTSW |
1 |
63,341,900 (GRCm39) |
missense |
unknown |
|
|
R1720:Zdbf2
|
UTSW |
1 |
63,342,436 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R1853:Zdbf2
|
UTSW |
1 |
63,344,701 (GRCm39) |
frame shift |
probably null |
|
|
R1854:Zdbf2
|
UTSW |
1 |
63,344,701 (GRCm39) |
frame shift |
probably null |
|
|
R1973:Zdbf2
|
UTSW |
1 |
63,348,860 (GRCm39) |
missense |
unknown |
|
|
R2336:Zdbf2
|
UTSW |
1 |
63,342,623 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2428:Zdbf2
|
UTSW |
1 |
63,344,774 (GRCm39) |
missense |
probably benign |
0.04 |
|
R3010:Zdbf2
|
UTSW |
1 |
63,342,224 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R3034:Zdbf2
|
UTSW |
1 |
63,343,364 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R3079:Zdbf2
|
UTSW |
1 |
63,346,636 (GRCm39) |
missense |
probably benign |
0.05 |
|
R3196:Zdbf2
|
UTSW |
1 |
63,347,579 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R3711:Zdbf2
|
UTSW |
1 |
63,347,830 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R3845:Zdbf2
|
UTSW |
1 |
63,347,483 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R4093:Zdbf2
|
UTSW |
1 |
63,348,940 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R4250:Zdbf2
|
UTSW |
1 |
63,342,020 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R4592:Zdbf2
|
UTSW |
1 |
63,345,750 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R4721:Zdbf2
|
UTSW |
1 |
63,347,951 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R4779:Zdbf2
|
UTSW |
1 |
63,342,397 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R4928:Zdbf2
|
UTSW |
1 |
63,347,973 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R4943:Zdbf2
|
UTSW |
1 |
63,342,073 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R5025:Zdbf2
|
UTSW |
1 |
63,342,809 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R5095:Zdbf2
|
UTSW |
1 |
63,348,232 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R5149:Zdbf2
|
UTSW |
1 |
63,344,062 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R5326:Zdbf2
|
UTSW |
1 |
63,343,570 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R5341:Zdbf2
|
UTSW |
1 |
63,347,092 (GRCm39) |
missense |
probably benign |
0.27 |
|
R5511:Zdbf2
|
UTSW |
1 |
63,344,836 (GRCm39) |
missense |
probably benign |
0.03 |
|
R5809:Zdbf2
|
UTSW |
1 |
63,345,035 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R5902:Zdbf2
|
UTSW |
1 |
63,345,685 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R6162:Zdbf2
|
UTSW |
1 |
63,319,977 (GRCm39) |
start gained |
probably benign |
|
|
R6245:Zdbf2
|
UTSW |
1 |
63,343,592 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R6332:Zdbf2
|
UTSW |
1 |
63,346,981 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R6361:Zdbf2
|
UTSW |
1 |
63,342,480 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R6489:Zdbf2
|
UTSW |
1 |
63,346,637 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R6517:Zdbf2
|
UTSW |
1 |
63,344,679 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R6624:Zdbf2
|
UTSW |
1 |
63,343,073 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R6643:Zdbf2
|
UTSW |
1 |
63,343,667 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R6786:Zdbf2
|
UTSW |
1 |
63,343,679 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R6808:Zdbf2
|
UTSW |
1 |
63,347,687 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R6896:Zdbf2
|
UTSW |
1 |
63,348,031 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6997:Zdbf2
|
UTSW |
1 |
63,329,925 (GRCm39) |
missense |
probably benign |
0.09 |
|
R7011:Zdbf2
|
UTSW |
1 |
63,345,925 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R7066:Zdbf2
|
UTSW |
1 |
63,346,718 (GRCm39) |
missense |
probably benign |
|
|
R7177:Zdbf2
|
UTSW |
1 |
63,334,120 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R7184:Zdbf2
|
UTSW |
1 |
63,345,664 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R7273:Zdbf2
|
UTSW |
1 |
63,342,563 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R7387:Zdbf2
|
UTSW |
1 |
63,343,198 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R7468:Zdbf2
|
UTSW |
1 |
63,346,669 (GRCm39) |
missense |
probably benign |
|
|
R7695:Zdbf2
|
UTSW |
1 |
63,346,529 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R7712:Zdbf2
|
UTSW |
1 |
63,344,530 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R7735:Zdbf2
|
UTSW |
1 |
63,343,264 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R7736:Zdbf2
|
UTSW |
1 |
63,347,166 (GRCm39) |
nonsense |
probably null |
|
|
R7759:Zdbf2
|
UTSW |
1 |
63,347,535 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R7796:Zdbf2
|
UTSW |
1 |
63,342,583 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R7908:Zdbf2
|
UTSW |
1 |
63,345,986 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R7970:Zdbf2
|
UTSW |
1 |
63,343,330 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R8076:Zdbf2
|
UTSW |
1 |
63,345,260 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R8152:Zdbf2
|
UTSW |
1 |
63,345,572 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R8195:Zdbf2
|
UTSW |
1 |
63,343,225 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R8272:Zdbf2
|
UTSW |
1 |
63,345,142 (GRCm39) |
missense |
probably benign |
|
|
R8306:Zdbf2
|
UTSW |
1 |
63,343,234 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R8309:Zdbf2
|
UTSW |
1 |
63,345,750 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R8323:Zdbf2
|
UTSW |
1 |
63,342,073 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R8400:Zdbf2
|
UTSW |
1 |
63,344,135 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R8443:Zdbf2
|
UTSW |
1 |
63,345,166 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R8460:Zdbf2
|
UTSW |
1 |
63,348,729 (GRCm39) |
small deletion |
probably benign |
|
|
R8528:Zdbf2
|
UTSW |
1 |
63,342,545 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R8812:Zdbf2
|
UTSW |
1 |
63,347,272 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8962:Zdbf2
|
UTSW |
1 |
63,347,162 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9061:Zdbf2
|
UTSW |
1 |
63,346,296 (GRCm39) |
missense |
|
|
|
R9072:Zdbf2
|
UTSW |
1 |
63,344,923 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R9232:Zdbf2
|
UTSW |
1 |
63,347,168 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R9257:Zdbf2
|
UTSW |
1 |
63,345,400 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9411:Zdbf2
|
UTSW |
1 |
63,343,288 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R9470:Zdbf2
|
UTSW |
1 |
63,344,784 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R9606:Zdbf2
|
UTSW |
1 |
63,342,536 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R9621:Zdbf2
|
UTSW |
1 |
63,342,635 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
RF021:Zdbf2
|
UTSW |
1 |
63,341,811 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
X0018:Zdbf2
|
UTSW |
1 |
63,344,510 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
X0027:Zdbf2
|
UTSW |
1 |
63,347,166 (GRCm39) |
nonsense |
probably null |
|
|
X0057:Zdbf2
|
UTSW |
1 |
63,344,549 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
X0063:Zdbf2
|
UTSW |
1 |
63,344,696 (GRCm39) |
missense |
probably benign |
0.04 |
|
Z1176:Zdbf2
|
UTSW |
1 |
63,343,404 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
Z1177:Zdbf2
|
UTSW |
1 |
63,348,362 (GRCm39) |
missense |
unknown |
|
|
Z1177:Zdbf2
|
UTSW |
1 |
63,343,245 (GRCm39) |
frame shift |
probably null |
|
|
| Predicted Primers |
PCR Primer
(F):5'- CCACCTCAGATGACTGTCAAAG -3'
(R):5'- TTCCGAAGACTGGTGGCTTC -3'
Sequencing Primer
(F):5'- TCAGATGACTGTCAAAGAAACCAGTG -3'
(R):5'- TGGCTTCTCCAGTTTTCTGTAG -3'
|
| Posted On |
2019-05-13 |
Incidental Mutation