Incidental Mutation 'R7069:Pcdh7'
| ID |
548739 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Pcdh7
|
| Ensembl Gene |
ENSMUSG00000029108 |
| Gene Name |
protocadherin 7 |
| Synonyms |
BH-protocadherin |
| MMRRC Submission |
045165-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.141)
|
| Stock # |
R7069 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
5 |
| Chromosomal Location |
57875309-58290572 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 57877126 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Aspartic acid to Glycine
at position 227
(D227G)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000066306
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000068110]
[ENSMUST00000094783]
[ENSMUST00000191837]
[ENSMUST00000199310]
|
| AlphaFold |
A0A0A6YY83 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000068110
AA Change: D227G
PolyPhen 2
Score 0.001 (Sensitivity: 0.99; Specificity: 0.15)
|
| SMART Domains |
Protein: ENSMUSP00000066306
Gene: ENSMUSG00000029108
AA Change: D227G
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
30 |
N/A |
INTRINSIC |
|
CA
|
48 |
141 |
7.29e-4 |
SMART |
|
CA
|
165 |
306 |
1.13e-18 |
SMART |
|
CA
|
330 |
413 |
2.12e-23 |
SMART |
|
CA
|
445 |
533 |
1.53e-20 |
SMART |
|
CA
|
557 |
637 |
1.36e-26 |
SMART |
|
CA
|
661 |
740 |
2.38e-26 |
SMART |
|
CA
|
766 |
847 |
2.01e-15 |
SMART |
|
transmembrane domain
|
878 |
900 |
N/A |
INTRINSIC |
|
low complexity region
|
929 |
944 |
N/A |
INTRINSIC |
|
| Predicted Effect |
|
| SMART Domains |
Protein: ENSMUSP00000092376
Gene: ENSMUSG00000029108
AA Change: D227G
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
30 |
N/A |
INTRINSIC |
|
CA
|
48 |
141 |
7.29e-4 |
SMART |
|
CA
|
165 |
306 |
1.13e-18 |
SMART |
|
CA
|
330 |
413 |
2.12e-23 |
SMART |
|
CA
|
445 |
533 |
1.53e-20 |
SMART |
|
CA
|
557 |
637 |
1.36e-26 |
SMART |
|
CA
|
661 |
740 |
2.38e-26 |
SMART |
|
CA
|
766 |
847 |
2.01e-15 |
SMART |
|
transmembrane domain
|
878 |
900 |
N/A |
INTRINSIC |
|
low complexity region
|
929 |
944 |
N/A |
INTRINSIC |
|
low complexity region
|
1088 |
1099 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000191837
AA Change: D227G
PolyPhen 2
Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
|
| SMART Domains |
Protein: ENSMUSP00000142319
Gene: ENSMUSG00000029108
AA Change: D227G
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
30 |
N/A |
INTRINSIC |
|
CA
|
48 |
141 |
7.29e-4 |
SMART |
|
CA
|
165 |
306 |
1.13e-18 |
SMART |
|
CA
|
330 |
413 |
2.12e-23 |
SMART |
|
CA
|
445 |
533 |
1.53e-20 |
SMART |
|
CA
|
557 |
637 |
1.36e-26 |
SMART |
|
CA
|
661 |
740 |
2.38e-26 |
SMART |
|
CA
|
766 |
847 |
2.01e-15 |
SMART |
|
transmembrane domain
|
878 |
900 |
N/A |
INTRINSIC |
|
low complexity region
|
929 |
944 |
N/A |
INTRINSIC |
|
low complexity region
|
1088 |
1099 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000192048
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000192287
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000195156
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000199310
|
| SMART Domains |
Protein: ENSMUSP00000143387
Gene: ENSMUSG00000029108
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Protocadherin
|
1 |
79 |
5.1e-40 |
PFAM |
|
low complexity region
|
112 |
123 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.6%
- 20x: 98.8%
|
| Validation Efficiency |
98% (86/88) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. The gene encodes a protein with an extracellular domain containing 7 cadherin repeats. The gene product is an integral membrane protein that is thought to function in cell-cell recognition and adhesion. Alternative splicing yields isoforms with unique cytoplasmic tails. [provided by RefSeq, Jul 2008]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 89 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Aasdh |
T |
A |
5: 77,024,203 (GRCm39) |
I991L |
probably benign |
Het |
| Abtb3 |
C |
A |
10: 85,223,520 (GRCm39) |
R110S |
unknown |
Het |
| Actg2 |
C |
A |
6: 83,497,745 (GRCm39) |
G96V |
probably damaging |
Het |
| Adh5 |
T |
A |
3: 138,156,812 (GRCm39) |
L166* |
probably null |
Het |
| Akap13 |
A |
G |
7: 75,260,010 (GRCm39) |
D75G |
probably benign |
Het |
| Ank2 |
T |
C |
3: 126,739,947 (GRCm39) |
|
probably benign |
Het |
| Arfgap1 |
T |
A |
2: 180,615,913 (GRCm39) |
D197E |
probably benign |
Het |
| Aste1 |
T |
C |
9: 105,273,906 (GRCm39) |
|
probably null |
Het |
| Atp8b2 |
T |
A |
3: 89,861,878 (GRCm39) |
N78I |
probably damaging |
Het |
| Cacna2d3 |
T |
A |
14: 28,691,260 (GRCm39) |
|
probably benign |
Het |
| Chrd |
T |
A |
16: 20,558,183 (GRCm39) |
W809R |
probably damaging |
Het |
| Col2a1 |
C |
T |
15: 97,896,469 (GRCm39) |
G60D |
unknown |
Het |
| Coro7 |
T |
A |
16: 4,497,475 (GRCm39) |
M1L |
probably damaging |
Het |
| Cracdl |
A |
T |
1: 37,670,982 (GRCm39) |
F97Y |
probably damaging |
Het |
| Dhx40 |
T |
C |
11: 86,688,569 (GRCm39) |
I285V |
probably benign |
Het |
| Dop1a |
T |
C |
9: 86,432,222 (GRCm39) |
|
probably null |
Het |
| Enox1 |
A |
T |
14: 77,848,764 (GRCm39) |
R358S |
probably damaging |
Het |
| Ep400 |
A |
G |
5: 110,815,990 (GRCm39) |
V2724A |
probably damaging |
Het |
| Fam221a |
A |
C |
6: 49,355,432 (GRCm39) |
Q178P |
probably damaging |
Het |
| Fcho1 |
A |
C |
8: 72,163,141 (GRCm39) |
|
probably null |
Het |
| Fndc1 |
A |
T |
17: 7,988,567 (GRCm39) |
V1165D |
unknown |
Het |
| Gal3st2b |
A |
T |
1: 93,868,341 (GRCm39) |
N189Y |
possibly damaging |
Het |
| Ghr |
T |
A |
15: 3,349,966 (GRCm39) |
D404V |
probably damaging |
Het |
| Glis3 |
A |
T |
19: 28,508,919 (GRCm39) |
V355D |
probably damaging |
Het |
| Gpr12 |
A |
C |
5: 146,520,349 (GRCm39) |
V32G |
possibly damaging |
Het |
| Gspt1 |
T |
A |
16: 11,040,525 (GRCm39) |
L593F |
probably damaging |
Het |
| H2-Q7 |
A |
T |
17: 35,659,007 (GRCm39) |
T153S |
probably damaging |
Het |
| Hars2 |
A |
G |
18: 36,921,009 (GRCm39) |
I194V |
probably damaging |
Het |
| Hdac9 |
T |
A |
12: 34,479,548 (GRCm39) |
T202S |
possibly damaging |
Het |
| Hoxd13 |
T |
C |
2: 74,499,368 (GRCm39) |
Y239H |
probably damaging |
Het |
| Insm2 |
C |
T |
12: 55,646,621 (GRCm39) |
Q122* |
probably null |
Het |
| Insyn2b |
T |
A |
11: 34,352,677 (GRCm39) |
C240S |
possibly damaging |
Het |
| Ip6k1 |
T |
A |
9: 107,922,651 (GRCm39) |
|
probably null |
Het |
| Ippk |
T |
C |
13: 49,615,219 (GRCm39) |
V534A |
probably damaging |
Het |
| Itch |
T |
G |
2: 155,051,914 (GRCm39) |
F611C |
probably damaging |
Het |
| Itga1 |
A |
T |
13: 115,104,776 (GRCm39) |
N1083K |
probably damaging |
Het |
| Itgae |
A |
C |
11: 73,006,969 (GRCm39) |
D405A |
probably damaging |
Het |
| Kif18a |
T |
C |
2: 109,125,347 (GRCm39) |
S255P |
probably damaging |
Het |
| Klhl24 |
C |
G |
16: 19,926,231 (GRCm39) |
T253R |
probably benign |
Het |
| Krt81 |
T |
A |
15: 101,358,609 (GRCm39) |
T307S |
possibly damaging |
Het |
| Lbr |
A |
T |
1: 181,656,354 (GRCm39) |
W265R |
probably damaging |
Het |
| Lgals3bp |
T |
C |
11: 118,283,999 (GRCm39) |
T527A |
probably benign |
Het |
| Lzts1 |
A |
C |
8: 69,593,397 (GRCm39) |
V70G |
probably damaging |
Het |
| Map3k6 |
C |
T |
4: 132,979,023 (GRCm39) |
P1154S |
probably benign |
Het |
| Masp1 |
T |
C |
16: 23,271,205 (GRCm39) |
D681G |
probably benign |
Het |
| Mdga2 |
T |
C |
12: 66,533,526 (GRCm39) |
N948D |
probably benign |
Het |
| Mettl4 |
A |
T |
17: 95,041,061 (GRCm39) |
F364L |
probably damaging |
Het |
| Mosmo |
T |
C |
7: 120,277,055 (GRCm39) |
I23T |
probably benign |
Het |
| Mtg1 |
G |
A |
7: 139,723,657 (GRCm39) |
V96I |
probably benign |
Het |
| Myh11 |
T |
A |
16: 14,036,803 (GRCm39) |
R966S |
possibly damaging |
Het |
| Ncapg2 |
A |
G |
12: 116,388,337 (GRCm39) |
|
probably null |
Het |
| Nid1 |
G |
A |
13: 13,683,353 (GRCm39) |
V1144I |
probably benign |
Het |
| Or4a77 |
T |
C |
2: 89,486,910 (GRCm39) |
I292V |
probably benign |
Het |
| Or52a33 |
A |
T |
7: 103,289,167 (GRCm39) |
M60K |
probably damaging |
Het |
| Or55b4 |
C |
A |
7: 102,133,979 (GRCm39) |
C116F |
possibly damaging |
Het |
| Oscar |
T |
G |
7: 3,614,238 (GRCm39) |
Y167S |
probably damaging |
Het |
| Pa2g4 |
T |
C |
10: 128,396,559 (GRCm39) |
T200A |
probably benign |
Het |
| Pira1 |
C |
G |
7: 3,740,319 (GRCm39) |
A301P |
probably damaging |
Het |
| Plce1 |
G |
A |
19: 38,747,384 (GRCm39) |
G1702R |
probably damaging |
Het |
| Plxna2 |
C |
A |
1: 194,476,212 (GRCm39) |
T1144K |
possibly damaging |
Het |
| Prl8a8 |
G |
A |
13: 27,695,450 (GRCm39) |
T99I |
probably benign |
Het |
| Prr29 |
C |
A |
11: 106,267,085 (GRCm39) |
H83Q |
probably damaging |
Het |
| Raly |
T |
A |
2: 154,701,664 (GRCm39) |
I108N |
possibly damaging |
Het |
| Ranbp9 |
A |
T |
13: 43,573,098 (GRCm39) |
S475R |
probably benign |
Het |
| Rogdi |
C |
A |
16: 4,831,362 (GRCm39) |
|
probably benign |
Het |
| Rorc |
C |
T |
3: 94,280,214 (GRCm39) |
Q6* |
probably null |
Het |
| Sacs |
T |
C |
14: 61,449,945 (GRCm39) |
L3997S |
probably damaging |
Het |
| Scn2a |
A |
T |
2: 65,594,950 (GRCm39) |
Y1933F |
probably benign |
Het |
| Sik3 |
T |
C |
9: 46,122,041 (GRCm39) |
L898P |
probably damaging |
Het |
| Sipa1l1 |
A |
G |
12: 82,388,180 (GRCm39) |
I135M |
probably damaging |
Het |
| Slc26a3 |
C |
A |
12: 31,500,934 (GRCm39) |
Q224K |
probably damaging |
Het |
| Sobp |
G |
T |
10: 42,897,436 (GRCm39) |
N716K |
probably benign |
Het |
| Spata16 |
A |
G |
3: 26,981,483 (GRCm39) |
D513G |
probably damaging |
Het |
| Spata31h1 |
G |
A |
10: 82,125,777 (GRCm39) |
T2411I |
probably damaging |
Het |
| Speer4a3 |
A |
T |
5: 26,154,842 (GRCm39) |
S253T |
possibly damaging |
Het |
| Stac |
T |
C |
9: 111,401,394 (GRCm39) |
R351G |
possibly damaging |
Het |
| Tecta |
T |
A |
9: 42,306,237 (GRCm39) |
T64S |
probably benign |
Het |
| Tert |
G |
A |
13: 73,776,529 (GRCm39) |
V427M |
probably damaging |
Het |
| Tex15 |
G |
A |
8: 34,060,748 (GRCm39) |
M333I |
probably benign |
Het |
| Tmbim4 |
A |
T |
10: 120,056,664 (GRCm39) |
Q72L |
probably benign |
Het |
| Trav9n-4 |
T |
C |
14: 53,532,256 (GRCm39) |
S37P |
probably benign |
Het |
| Trpv5 |
A |
T |
6: 41,652,894 (GRCm39) |
M93K |
possibly damaging |
Het |
| Ulk4 |
T |
C |
9: 121,087,876 (GRCm39) |
E272G |
probably benign |
Het |
| Ulk4 |
T |
C |
9: 121,095,583 (GRCm39) |
T79A |
probably benign |
Het |
| Upb1 |
A |
G |
10: 75,248,602 (GRCm39) |
N41D |
probably benign |
Het |
| Wls |
A |
T |
3: 159,639,965 (GRCm39) |
Y532F |
probably damaging |
Het |
| Zdhhc5 |
G |
A |
2: 84,545,355 (GRCm39) |
|
probably benign |
Het |
| Zfp109 |
T |
C |
7: 23,928,785 (GRCm39) |
D216G |
probably benign |
Het |
| Zfp473 |
G |
A |
7: 44,381,798 (GRCm39) |
A845V |
probably damaging |
Het |
|
| Other mutations in Pcdh7 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00790:Pcdh7
|
APN |
5 |
57,878,806 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00920:Pcdh7
|
APN |
5 |
57,877,473 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL00990:Pcdh7
|
APN |
5 |
57,877,806 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
IGL01367:Pcdh7
|
APN |
5 |
58,286,566 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
IGL01388:Pcdh7
|
APN |
5 |
57,877,546 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01543:Pcdh7
|
APN |
5 |
57,878,107 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01750:Pcdh7
|
APN |
5 |
57,877,764 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02010:Pcdh7
|
APN |
5 |
58,286,597 (GRCm39) |
missense |
probably benign |
|
|
IGL02014:Pcdh7
|
APN |
5 |
57,877,045 (GRCm39) |
missense |
probably benign |
0.03 |
|
IGL02269:Pcdh7
|
APN |
5 |
58,070,664 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03051:Pcdh7
|
APN |
5 |
58,286,415 (GRCm39) |
missense |
probably damaging |
0.99 |
|
floated
|
UTSW |
5 |
57,878,704 (GRCm39) |
missense |
probably damaging |
1.00 |
|
proposed
|
UTSW |
5 |
57,879,582 (GRCm39) |
missense |
probably damaging |
0.99 |
|
P0037:Pcdh7
|
UTSW |
5 |
58,070,590 (GRCm39) |
missense |
probably benign |
0.17 |
|
R0003:Pcdh7
|
UTSW |
5 |
58,070,590 (GRCm39) |
missense |
probably benign |
0.17 |
|
R0421:Pcdh7
|
UTSW |
5 |
57,877,402 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0551:Pcdh7
|
UTSW |
5 |
57,879,336 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0562:Pcdh7
|
UTSW |
5 |
57,877,405 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0732:Pcdh7
|
UTSW |
5 |
57,878,657 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0755:Pcdh7
|
UTSW |
5 |
57,877,664 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R1080:Pcdh7
|
UTSW |
5 |
57,876,768 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1381:Pcdh7
|
UTSW |
5 |
57,878,882 (GRCm39) |
nonsense |
probably null |
|
|
R1591:Pcdh7
|
UTSW |
5 |
57,877,764 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1891:Pcdh7
|
UTSW |
5 |
57,878,217 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R2011:Pcdh7
|
UTSW |
5 |
57,876,971 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2140:Pcdh7
|
UTSW |
5 |
58,286,338 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2147:Pcdh7
|
UTSW |
5 |
58,286,458 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R2848:Pcdh7
|
UTSW |
5 |
57,877,618 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2867:Pcdh7
|
UTSW |
5 |
57,879,236 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2867:Pcdh7
|
UTSW |
5 |
57,879,236 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3719:Pcdh7
|
UTSW |
5 |
58,286,374 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4075:Pcdh7
|
UTSW |
5 |
57,879,150 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4231:Pcdh7
|
UTSW |
5 |
57,876,631 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R4236:Pcdh7
|
UTSW |
5 |
57,876,631 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R4352:Pcdh7
|
UTSW |
5 |
57,879,361 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R4420:Pcdh7
|
UTSW |
5 |
58,286,512 (GRCm39) |
missense |
probably benign |
0.03 |
|
R4449:Pcdh7
|
UTSW |
5 |
57,877,827 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4584:Pcdh7
|
UTSW |
5 |
57,878,625 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4686:Pcdh7
|
UTSW |
5 |
58,286,511 (GRCm39) |
missense |
probably benign |
|
|
R4837:Pcdh7
|
UTSW |
5 |
57,877,753 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R4838:Pcdh7
|
UTSW |
5 |
57,878,146 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4947:Pcdh7
|
UTSW |
5 |
57,879,258 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5053:Pcdh7
|
UTSW |
5 |
57,878,943 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5068:Pcdh7
|
UTSW |
5 |
57,879,508 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5117:Pcdh7
|
UTSW |
5 |
57,879,090 (GRCm39) |
missense |
probably benign |
0.09 |
|
R5132:Pcdh7
|
UTSW |
5 |
57,885,463 (GRCm39) |
missense |
probably benign |
|
|
R5248:Pcdh7
|
UTSW |
5 |
58,286,515 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R5294:Pcdh7
|
UTSW |
5 |
57,885,453 (GRCm39) |
splice site |
probably null |
|
|
R5420:Pcdh7
|
UTSW |
5 |
57,877,529 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5777:Pcdh7
|
UTSW |
5 |
57,876,856 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5800:Pcdh7
|
UTSW |
5 |
57,879,567 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5834:Pcdh7
|
UTSW |
5 |
57,878,970 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R5870:Pcdh7
|
UTSW |
5 |
57,877,753 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R5917:Pcdh7
|
UTSW |
5 |
57,879,097 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R6014:Pcdh7
|
UTSW |
5 |
57,878,497 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6193:Pcdh7
|
UTSW |
5 |
57,877,666 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6240:Pcdh7
|
UTSW |
5 |
57,878,704 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6335:Pcdh7
|
UTSW |
5 |
58,099,607 (GRCm39) |
splice site |
probably null |
|
|
R6418:Pcdh7
|
UTSW |
5 |
57,879,046 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6907:Pcdh7
|
UTSW |
5 |
57,876,471 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R7058:Pcdh7
|
UTSW |
5 |
57,879,582 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7073:Pcdh7
|
UTSW |
5 |
57,878,299 (GRCm39) |
missense |
probably benign |
0.19 |
|
R7463:Pcdh7
|
UTSW |
5 |
57,878,340 (GRCm39) |
missense |
probably benign |
0.06 |
|
R7509:Pcdh7
|
UTSW |
5 |
57,877,529 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7588:Pcdh7
|
UTSW |
5 |
57,877,246 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7707:Pcdh7
|
UTSW |
5 |
57,877,672 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7734:Pcdh7
|
UTSW |
5 |
57,876,976 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7899:Pcdh7
|
UTSW |
5 |
57,877,152 (GRCm39) |
missense |
probably benign |
|
|
R8194:Pcdh7
|
UTSW |
5 |
57,877,678 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8480:Pcdh7
|
UTSW |
5 |
58,286,407 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8890:Pcdh7
|
UTSW |
5 |
57,876,717 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8906:Pcdh7
|
UTSW |
5 |
57,879,154 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8990:Pcdh7
|
UTSW |
5 |
57,879,364 (GRCm39) |
missense |
probably benign |
0.06 |
|
R9264:Pcdh7
|
UTSW |
5 |
58,286,663 (GRCm39) |
missense |
probably benign |
0.09 |
|
R9272:Pcdh7
|
UTSW |
5 |
57,878,779 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R9294:Pcdh7
|
UTSW |
5 |
57,878,677 (GRCm39) |
missense |
probably benign |
0.39 |
|
R9518:Pcdh7
|
UTSW |
5 |
58,070,513 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R9597:Pcdh7
|
UTSW |
5 |
57,877,197 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R9642:Pcdh7
|
UTSW |
5 |
57,876,717 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9745:Pcdh7
|
UTSW |
5 |
57,879,622 (GRCm39) |
critical splice donor site |
probably null |
|
|
X0021:Pcdh7
|
UTSW |
5 |
57,878,826 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
X0026:Pcdh7
|
UTSW |
5 |
57,876,721 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Pcdh7
|
UTSW |
5 |
57,877,006 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
| Predicted Primers |
PCR Primer
(F):5'- CTTTGGTCGCAATGGCATCG -3'
(R):5'- GCTGTTGTCATTCACGTCG -3'
Sequencing Primer
(F):5'- ATGGCATCGAACGCTACG -3'
(R):5'- TGATGAGCACCCGCAAG -3'
|
| Posted On |
2019-05-13 |
Incidental Mutation