Mutagenetix > Incidental Mutation

Incidental Mutation 'R7069:Tecta'

548757

Institutional Source

Beutler Lab

Gene Symbol

Tecta

Ensembl Gene

ENSMUSG00000037705

Gene Name

tectorin alpha

Synonyms

[a]-tectorin, Tctna

MMRRC Submission

045165-MU

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.152) question?

Stock #

R7069 (G1)

Quality Score

225.009

Status

Validated

Chromosome

Chromosomal Location

42240915-42311225 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

T to A at 42306237 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Threonine to Serine at position 64 (T64S)

Ref Sequence

ENSEMBL: ENSMUSP00000125370 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000042190] [ENSMUST00000160940]

AlphaFold

O08523

Predicted Effect

probably benign
Transcript: ENSMUST00000042190
AA Change: T64S

PolyPhen 2 Score 0.016 (Sensitivity: 0.95; Specificity: 0.79)

SMART Domains

Protein: ENSMUSP00000040262
Gene: ENSMUSG00000037705
AA Change: T64S

Domain	Start	End	E-Value	Type
signal peptide	1	22	N/A	INTRINSIC
NIDO	98	254	7.88e-77	SMART
VWC	260	314	1.04e0	SMART
VWD	312	477	1.5e-58	SMART
C8	517	592	7.06e-29	SMART
EGF_like	622	645	3.87e1	SMART
VWC	652	713	1.87e-1	SMART
VWD	703	865	4.44e-43	SMART
C8	905	981	9.19e-19	SMART
Pfam:TIL	984	1036	9.8e-13	PFAM
VWD	1090	1257	1.44e-51	SMART
C8	1294	1369	4.64e-15	SMART
EGF_like	1388	1420	5.34e1	SMART
VWC	1427	1487	2.88e-19	SMART
VWD	1477	1638	2.72e-38	SMART
C8	1684	1758	6.51e-10	SMART
ZP	1805	2059	2.95e-85	SMART
EGF	2087	2122	2.07e1	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000160940
AA Change: T64S

PolyPhen 2 Score 0.027 (Sensitivity: 0.95; Specificity: 0.81)

SMART Domains

Protein: ENSMUSP00000125370
Gene: ENSMUSG00000037705
AA Change: T64S

Domain	Start	End	E-Value	Type
signal peptide	1	22	N/A	INTRINSIC
NIDO	98	254	7.88e-77	SMART
VWC	260	314	1.04e0	SMART
VWD	312	477	1.5e-58	SMART
C8	517	592	7.06e-29	SMART
EGF_like	622	645	3.87e1	SMART
VWC	652	713	1.87e-1	SMART
VWD	703	865	4.44e-43	SMART
C8	905	981	9.19e-19	SMART
Pfam:TIL	984	1036	6.1e-13	PFAM
VWD	1090	1257	1.44e-51	SMART
C8	1294	1369	4.64e-15	SMART
EGF_like	1388	1420	5.34e1	SMART
VWC	1427	1487	2.88e-19	SMART
VWD	1477	1638	2.72e-38	SMART
C8	1679	1753	6.51e-10	SMART
ZP	1800	2054	2.95e-85	SMART
EGF	2082	2117	2.07e1	SMART

Coding Region Coverage

1x: 100.0%
3x: 99.9%
10x: 99.6%
20x: 98.8%

Validation Efficiency

98% (86/88)

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The tectorial membrane is an extracellular matrix of the inner ear that contacts the stereocilia bundles of specialized sensory hair cells. Sound induces movement of these hair cells relative to the tectorial membrane, deflects the stereocilia, and leads to fluctuations in hair-cell membrane potential, transducing sound into electrical signals. Alpha-tectorin is one of the major noncollagenous components of the tectorial membrane. Mutations in the TECTA gene have been shown to be responsible for autosomal dominant nonsyndromic hearing impairment and a recessive form of sensorineural pre-lingual non-syndromic deafness. [provided by RefSeq, Jul 2008]
PHENOTYPE: Homozygous null mice exhibit a tectorial membrane that is detached from the cochlear epithelium. Though the basilar membranes of mutant mice are tuned, sensitivity is attenuated. Mice with an Y1870C mutation have a disrupted tectorial membrane, elevated neural thresholds and broadened neural tuning. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 89 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Aasdh	T	A	5: 77,024,203 (GRCm39)	I991L	probably benign	Het
Abtb3	C	A	10: 85,223,520 (GRCm39)	R110S	unknown	Het
Actg2	C	A	6: 83,497,745 (GRCm39)	G96V	probably damaging	Het
Adh5	T	A	3: 138,156,812 (GRCm39)	L166*	probably null	Het
Akap13	A	G	7: 75,260,010 (GRCm39)	D75G	probably benign	Het
Ank2	T	C	3: 126,739,947 (GRCm39)		probably benign	Het
Arfgap1	T	A	2: 180,615,913 (GRCm39)	D197E	probably benign	Het
Aste1	T	C	9: 105,273,906 (GRCm39)		probably null	Het
Atp8b2	T	A	3: 89,861,878 (GRCm39)	N78I	probably damaging	Het
Cacna2d3	T	A	14: 28,691,260 (GRCm39)		probably benign	Het
Chrd	T	A	16: 20,558,183 (GRCm39)	W809R	probably damaging	Het
Col2a1	C	T	15: 97,896,469 (GRCm39)	G60D	unknown	Het
Coro7	T	A	16: 4,497,475 (GRCm39)	M1L	probably damaging	Het
Cracdl	A	T	1: 37,670,982 (GRCm39)	F97Y	probably damaging	Het
Dhx40	T	C	11: 86,688,569 (GRCm39)	I285V	probably benign	Het
Dop1a	T	C	9: 86,432,222 (GRCm39)		probably null	Het
Enox1	A	T	14: 77,848,764 (GRCm39)	R358S	probably damaging	Het
Ep400	A	G	5: 110,815,990 (GRCm39)	V2724A	probably damaging	Het
Fam221a	A	C	6: 49,355,432 (GRCm39)	Q178P	probably damaging	Het
Fcho1	A	C	8: 72,163,141 (GRCm39)		probably null	Het
Fndc1	A	T	17: 7,988,567 (GRCm39)	V1165D	unknown	Het
Gal3st2b	A	T	1: 93,868,341 (GRCm39)	N189Y	possibly damaging	Het
Ghr	T	A	15: 3,349,966 (GRCm39)	D404V	probably damaging	Het
Glis3	A	T	19: 28,508,919 (GRCm39)	V355D	probably damaging	Het
Gpr12	A	C	5: 146,520,349 (GRCm39)	V32G	possibly damaging	Het
Gspt1	T	A	16: 11,040,525 (GRCm39)	L593F	probably damaging	Het
H2-Q7	A	T	17: 35,659,007 (GRCm39)	T153S	probably damaging	Het
Hars2	A	G	18: 36,921,009 (GRCm39)	I194V	probably damaging	Het
Hdac9	T	A	12: 34,479,548 (GRCm39)	T202S	possibly damaging	Het
Hoxd13	T	C	2: 74,499,368 (GRCm39)	Y239H	probably damaging	Het
Insm2	C	T	12: 55,646,621 (GRCm39)	Q122*	probably null	Het
Insyn2b	T	A	11: 34,352,677 (GRCm39)	C240S	possibly damaging	Het
Ip6k1	T	A	9: 107,922,651 (GRCm39)		probably null	Het
Ippk	T	C	13: 49,615,219 (GRCm39)	V534A	probably damaging	Het
Itch	T	G	2: 155,051,914 (GRCm39)	F611C	probably damaging	Het
Itga1	A	T	13: 115,104,776 (GRCm39)	N1083K	probably damaging	Het
Itgae	A	C	11: 73,006,969 (GRCm39)	D405A	probably damaging	Het
Kif18a	T	C	2: 109,125,347 (GRCm39)	S255P	probably damaging	Het
Klhl24	C	G	16: 19,926,231 (GRCm39)	T253R	probably benign	Het
Krt81	T	A	15: 101,358,609 (GRCm39)	T307S	possibly damaging	Het
Lbr	A	T	1: 181,656,354 (GRCm39)	W265R	probably damaging	Het
Lgals3bp	T	C	11: 118,283,999 (GRCm39)	T527A	probably benign	Het
Lzts1	A	C	8: 69,593,397 (GRCm39)	V70G	probably damaging	Het
Map3k6	C	T	4: 132,979,023 (GRCm39)	P1154S	probably benign	Het
Masp1	T	C	16: 23,271,205 (GRCm39)	D681G	probably benign	Het
Mdga2	T	C	12: 66,533,526 (GRCm39)	N948D	probably benign	Het
Mettl4	A	T	17: 95,041,061 (GRCm39)	F364L	probably damaging	Het
Mosmo	T	C	7: 120,277,055 (GRCm39)	I23T	probably benign	Het
Mtg1	G	A	7: 139,723,657 (GRCm39)	V96I	probably benign	Het
Myh11	T	A	16: 14,036,803 (GRCm39)	R966S	possibly damaging	Het
Ncapg2	A	G	12: 116,388,337 (GRCm39)		probably null	Het
Nid1	G	A	13: 13,683,353 (GRCm39)	V1144I	probably benign	Het
Or4a77	T	C	2: 89,486,910 (GRCm39)	I292V	probably benign	Het
Or52a33	A	T	7: 103,289,167 (GRCm39)	M60K	probably damaging	Het
Or55b4	C	A	7: 102,133,979 (GRCm39)	C116F	possibly damaging	Het
Oscar	T	G	7: 3,614,238 (GRCm39)	Y167S	probably damaging	Het
Pa2g4	T	C	10: 128,396,559 (GRCm39)	T200A	probably benign	Het
Pcdh7	A	G	5: 57,877,126 (GRCm39)	D227G	probably benign	Het
Pira1	C	G	7: 3,740,319 (GRCm39)	A301P	probably damaging	Het
Plce1	G	A	19: 38,747,384 (GRCm39)	G1702R	probably damaging	Het
Plxna2	C	A	1: 194,476,212 (GRCm39)	T1144K	possibly damaging	Het
Prl8a8	G	A	13: 27,695,450 (GRCm39)	T99I	probably benign	Het
Prr29	C	A	11: 106,267,085 (GRCm39)	H83Q	probably damaging	Het
Raly	T	A	2: 154,701,664 (GRCm39)	I108N	possibly damaging	Het
Ranbp9	A	T	13: 43,573,098 (GRCm39)	S475R	probably benign	Het
Rogdi	C	A	16: 4,831,362 (GRCm39)		probably benign	Het
Rorc	C	T	3: 94,280,214 (GRCm39)	Q6*	probably null	Het
Sacs	T	C	14: 61,449,945 (GRCm39)	L3997S	probably damaging	Het
Scn2a	A	T	2: 65,594,950 (GRCm39)	Y1933F	probably benign	Het
Sik3	T	C	9: 46,122,041 (GRCm39)	L898P	probably damaging	Het
Sipa1l1	A	G	12: 82,388,180 (GRCm39)	I135M	probably damaging	Het
Slc26a3	C	A	12: 31,500,934 (GRCm39)	Q224K	probably damaging	Het
Sobp	G	T	10: 42,897,436 (GRCm39)	N716K	probably benign	Het
Spata16	A	G	3: 26,981,483 (GRCm39)	D513G	probably damaging	Het
Spata31h1	G	A	10: 82,125,777 (GRCm39)	T2411I	probably damaging	Het
Speer4a3	A	T	5: 26,154,842 (GRCm39)	S253T	possibly damaging	Het
Stac	T	C	9: 111,401,394 (GRCm39)	R351G	possibly damaging	Het
Tert	G	A	13: 73,776,529 (GRCm39)	V427M	probably damaging	Het
Tex15	G	A	8: 34,060,748 (GRCm39)	M333I	probably benign	Het
Tmbim4	A	T	10: 120,056,664 (GRCm39)	Q72L	probably benign	Het
Trav9n-4	T	C	14: 53,532,256 (GRCm39)	S37P	probably benign	Het
Trpv5	A	T	6: 41,652,894 (GRCm39)	M93K	possibly damaging	Het
Ulk4	T	C	9: 121,087,876 (GRCm39)	E272G	probably benign	Het
Ulk4	T	C	9: 121,095,583 (GRCm39)	T79A	probably benign	Het
Upb1	A	G	10: 75,248,602 (GRCm39)	N41D	probably benign	Het
Wls	A	T	3: 159,639,965 (GRCm39)	Y532F	probably damaging	Het
Zdhhc5	G	A	2: 84,545,355 (GRCm39)		probably benign	Het
Zfp109	T	C	7: 23,928,785 (GRCm39)	D216G	probably benign	Het
Zfp473	G	A	7: 44,381,798 (GRCm39)	A845V	probably damaging	Het

Other mutations in Tecta

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00466:Tecta	APN	9	42,243,844 (GRCm39)	missense	probably damaging	1.00
IGL00925:Tecta	APN	9	42,286,331 (GRCm39)	missense	probably benign
IGL00960:Tecta	APN	9	42,270,376 (GRCm39)	missense	possibly damaging	0.74
IGL00974:Tecta	APN	9	42,242,670 (GRCm39)	missense	probably benign	0.00
IGL01070:Tecta	APN	9	42,306,299 (GRCm39)	missense	probably damaging	1.00
IGL01284:Tecta	APN	9	42,256,916 (GRCm39)	missense	probably damaging	1.00
IGL01324:Tecta	APN	9	42,256,727 (GRCm39)	missense	probably damaging	1.00
IGL01694:Tecta	APN	9	42,278,475 (GRCm39)	missense	possibly damaging	0.92
IGL01861:Tecta	APN	9	42,284,658 (GRCm39)	missense	probably benign
IGL02010:Tecta	APN	9	42,248,489 (GRCm39)	missense	probably damaging	0.97
IGL02397:Tecta	APN	9	42,306,294 (GRCm39)	missense	probably damaging	1.00
IGL03031:Tecta	APN	9	42,256,789 (GRCm39)	missense	probably benign
IGL03208:Tecta	APN	9	42,248,396 (GRCm39)	splice site	probably benign
IGL03249:Tecta	APN	9	42,303,182 (GRCm39)	missense	probably benign	0.20
cover	UTSW	9	42,255,183 (GRCm39)	missense	probably benign	0.05
lid	UTSW	9	42,284,406 (GRCm39)	missense	probably damaging	0.99
R0004:Tecta	UTSW	9	42,256,774 (GRCm39)	missense	possibly damaging	0.74
R0045:Tecta	UTSW	9	42,286,487 (GRCm39)	missense	probably damaging	1.00
R0045:Tecta	UTSW	9	42,286,487 (GRCm39)	missense	probably damaging	1.00
R0119:Tecta	UTSW	9	42,263,359 (GRCm39)	missense	probably damaging	1.00
R0133:Tecta	UTSW	9	42,278,524 (GRCm39)	missense	probably benign	0.00
R0157:Tecta	UTSW	9	42,286,307 (GRCm39)	missense	probably benign
R0180:Tecta	UTSW	9	42,278,109 (GRCm39)	missense	probably benign
R0299:Tecta	UTSW	9	42,263,359 (GRCm39)	missense	probably damaging	1.00
R0345:Tecta	UTSW	9	42,295,514 (GRCm39)	missense	probably damaging	0.98
R0370:Tecta	UTSW	9	42,278,100 (GRCm39)	missense	probably benign
R0465:Tecta	UTSW	9	42,270,714 (GRCm39)	missense	possibly damaging	0.62
R0466:Tecta	UTSW	9	42,284,369 (GRCm39)	missense	probably benign
R0479:Tecta	UTSW	9	42,249,235 (GRCm39)	missense	probably damaging	1.00
R0498:Tecta	UTSW	9	42,288,910 (GRCm39)	missense	probably damaging	1.00
R0499:Tecta	UTSW	9	42,263,359 (GRCm39)	missense	probably damaging	1.00
R0519:Tecta	UTSW	9	42,259,188 (GRCm39)	splice site	probably benign
R0584:Tecta	UTSW	9	42,259,204 (GRCm39)	missense	possibly damaging	0.79
R0589:Tecta	UTSW	9	42,256,930 (GRCm39)	missense	probably benign	0.01
R0607:Tecta	UTSW	9	42,299,501 (GRCm39)	missense	probably damaging	1.00
R0691:Tecta	UTSW	9	42,295,637 (GRCm39)	missense	probably damaging	1.00
R0905:Tecta	UTSW	9	42,250,290 (GRCm39)	missense	probably damaging	1.00
R1216:Tecta	UTSW	9	42,289,203 (GRCm39)	missense	probably benign	0.44
R1239:Tecta	UTSW	9	42,243,781 (GRCm39)	missense	probably damaging	1.00
R1442:Tecta	UTSW	9	42,243,778 (GRCm39)	missense	probably damaging	1.00
R1553:Tecta	UTSW	9	42,259,482 (GRCm39)	missense	probably damaging	1.00
R1727:Tecta	UTSW	9	42,270,597 (GRCm39)	missense	probably damaging	0.96
R1728:Tecta	UTSW	9	42,303,218 (GRCm39)	missense	probably benign	0.12
R1729:Tecta	UTSW	9	42,303,218 (GRCm39)	missense	probably benign	0.12
R1762:Tecta	UTSW	9	42,286,605 (GRCm39)	missense	probably benign	0.30
R1778:Tecta	UTSW	9	42,254,927 (GRCm39)	missense	probably damaging	1.00
R1795:Tecta	UTSW	9	42,289,345 (GRCm39)	missense	probably benign
R1796:Tecta	UTSW	9	42,295,493 (GRCm39)	missense	probably damaging	1.00
R1866:Tecta	UTSW	9	42,303,320 (GRCm39)	missense	probably damaging	0.97
R1871:Tecta	UTSW	9	42,248,636 (GRCm39)	missense	probably damaging	1.00
R1871:Tecta	UTSW	9	42,248,472 (GRCm39)	missense	probably damaging	0.98
R1911:Tecta	UTSW	9	42,249,232 (GRCm39)	missense	probably damaging	1.00
R2074:Tecta	UTSW	9	42,248,575 (GRCm39)	nonsense	probably null
R2135:Tecta	UTSW	9	42,251,581 (GRCm39)	missense	probably damaging	1.00
R2171:Tecta	UTSW	9	42,270,220 (GRCm39)	missense	probably damaging	0.99
R2220:Tecta	UTSW	9	42,303,326 (GRCm39)	missense	probably damaging	1.00
R2372:Tecta	UTSW	9	42,299,570 (GRCm39)	missense	probably damaging	1.00
R2570:Tecta	UTSW	9	42,243,848 (GRCm39)	missense	probably damaging	1.00
R2939:Tecta	UTSW	9	42,289,290 (GRCm39)	missense	possibly damaging	0.63
R2940:Tecta	UTSW	9	42,289,290 (GRCm39)	missense	possibly damaging	0.63
R3081:Tecta	UTSW	9	42,289,290 (GRCm39)	missense	possibly damaging	0.63
R3407:Tecta	UTSW	9	42,249,150 (GRCm39)	missense	probably damaging	1.00
R3732:Tecta	UTSW	9	42,303,402 (GRCm39)	missense	possibly damaging	0.95
R3771:Tecta	UTSW	9	42,242,292 (GRCm39)	missense	probably damaging	1.00
R3772:Tecta	UTSW	9	42,242,292 (GRCm39)	missense	probably damaging	1.00
R3773:Tecta	UTSW	9	42,242,292 (GRCm39)	missense	probably damaging	1.00
R3832:Tecta	UTSW	9	42,250,329 (GRCm39)	missense	probably damaging	1.00
R4378:Tecta	UTSW	9	42,278,004 (GRCm39)	missense	probably damaging	1.00
R4480:Tecta	UTSW	9	42,284,529 (GRCm39)	missense	possibly damaging	0.75
R4485:Tecta	UTSW	9	42,248,570 (GRCm39)	missense	possibly damaging	0.73
R4804:Tecta	UTSW	9	42,309,533 (GRCm39)	missense	probably benign
R4869:Tecta	UTSW	9	42,286,830 (GRCm39)	missense	probably benign	0.02
R4944:Tecta	UTSW	9	42,241,573 (GRCm39)	missense	probably benign	0.05
R5008:Tecta	UTSW	9	42,284,358 (GRCm39)	missense	possibly damaging	0.76
R5014:Tecta	UTSW	9	42,284,538 (GRCm39)	missense	probably damaging	1.00
R5125:Tecta	UTSW	9	42,286,481 (GRCm39)	missense	probably damaging	1.00
R5178:Tecta	UTSW	9	42,286,481 (GRCm39)	missense	probably damaging	1.00
R5180:Tecta	UTSW	9	42,248,504 (GRCm39)	missense	probably damaging	1.00
R5214:Tecta	UTSW	9	42,256,964 (GRCm39)	missense	probably benign	0.04
R5230:Tecta	UTSW	9	42,306,239 (GRCm39)	missense	probably damaging	0.96
R5330:Tecta	UTSW	9	42,249,152 (GRCm39)	missense	probably damaging	1.00
R5387:Tecta	UTSW	9	42,286,359 (GRCm39)	missense	probably damaging	0.98
R5614:Tecta	UTSW	9	42,250,351 (GRCm39)	missense	probably damaging	1.00
R5708:Tecta	UTSW	9	42,250,222 (GRCm39)	missense	probably damaging	1.00
R5738:Tecta	UTSW	9	42,284,474 (GRCm39)	missense	possibly damaging	0.63
R5770:Tecta	UTSW	9	42,256,885 (GRCm39)	missense	possibly damaging	0.94
R5839:Tecta	UTSW	9	42,284,272 (GRCm39)	missense	possibly damaging	0.86
R5839:Tecta	UTSW	9	42,242,319 (GRCm39)	missense	probably benign	0.03
R6119:Tecta	UTSW	9	42,284,371 (GRCm39)	missense	probably benign	0.00
R6246:Tecta	UTSW	9	42,289,204 (GRCm39)	missense	probably benign	0.07
R6377:Tecta	UTSW	9	42,255,051 (GRCm39)	missense	probably damaging	1.00
R6416:Tecta	UTSW	9	42,286,563 (GRCm39)	missense	probably damaging	0.97
R6595:Tecta	UTSW	9	42,295,523 (GRCm39)	missense	probably damaging	1.00
R6850:Tecta	UTSW	9	42,255,134 (GRCm39)	missense	probably benign	0.20
R6859:Tecta	UTSW	9	42,303,425 (GRCm39)	missense	probably damaging	1.00
R6861:Tecta	UTSW	9	42,248,633 (GRCm39)	missense	possibly damaging	0.93
R6939:Tecta	UTSW	9	42,259,293 (GRCm39)	missense	probably damaging	1.00
R6996:Tecta	UTSW	9	42,278,082 (GRCm39)	missense	probably benign
R7104:Tecta	UTSW	9	42,278,239 (GRCm39)	missense	probably benign	0.00
R7129:Tecta	UTSW	9	42,259,287 (GRCm39)	missense	probably damaging	1.00
R7220:Tecta	UTSW	9	42,255,183 (GRCm39)	missense	probably benign	0.05
R7251:Tecta	UTSW	9	42,299,048 (GRCm39)	missense	probably damaging	1.00
R7307:Tecta	UTSW	9	42,289,288 (GRCm39)	missense	probably damaging	1.00
R7343:Tecta	UTSW	9	42,248,628 (GRCm39)	missense	probably damaging	1.00
R7355:Tecta	UTSW	9	42,278,438 (GRCm39)	nonsense	probably null
R7635:Tecta	UTSW	9	42,242,283 (GRCm39)	missense	probably benign	0.11
R7653:Tecta	UTSW	9	42,248,532 (GRCm39)	missense	probably damaging	1.00
R7723:Tecta	UTSW	9	42,278,232 (GRCm39)	missense	probably damaging	1.00
R7939:Tecta	UTSW	9	42,299,519 (GRCm39)	missense	probably damaging	0.99
R7966:Tecta	UTSW	9	42,306,258 (GRCm39)	missense	probably damaging	0.98
R7967:Tecta	UTSW	9	42,289,251 (GRCm39)	missense	possibly damaging	0.95
R8000:Tecta	UTSW	9	42,278,480 (GRCm39)	nonsense	probably null
R8064:Tecta	UTSW	9	42,306,251 (GRCm39)	missense	possibly damaging	0.94
R8117:Tecta	UTSW	9	42,288,927 (GRCm39)	missense	probably damaging	1.00
R8176:Tecta	UTSW	9	42,270,465 (GRCm39)	missense	probably damaging	0.97
R8284:Tecta	UTSW	9	42,289,325 (GRCm39)	missense	possibly damaging	0.89
R8315:Tecta	UTSW	9	42,299,121 (GRCm39)	critical splice acceptor site	probably null
R8321:Tecta	UTSW	9	42,284,349 (GRCm39)	missense	probably damaging	1.00
R8332:Tecta	UTSW	9	42,286,310 (GRCm39)	missense	probably damaging	1.00
R8437:Tecta	UTSW	9	42,243,856 (GRCm39)	missense	probably damaging	0.98
R8496:Tecta	UTSW	9	42,241,547 (GRCm39)	missense	probably benign	0.01
R8514:Tecta	UTSW	9	42,284,406 (GRCm39)	missense	probably damaging	0.99
R8683:Tecta	UTSW	9	42,278,268 (GRCm39)	missense	probably damaging	0.96
R8856:Tecta	UTSW	9	42,284,597 (GRCm39)	missense	probably benign	0.13
R8886:Tecta	UTSW	9	42,278,359 (GRCm39)	missense	probably benign	0.37
R9047:Tecta	UTSW	9	42,286,375 (GRCm39)	missense	probably benign	0.00
R9106:Tecta	UTSW	9	42,278,479 (GRCm39)	missense	probably benign	0.05
R9332:Tecta	UTSW	9	42,284,193 (GRCm39)	missense	probably damaging	1.00
R9352:Tecta	UTSW	9	42,249,147 (GRCm39)	missense	probably damaging	1.00
R9462:Tecta	UTSW	9	42,248,576 (GRCm39)	missense	probably damaging	1.00
R9535:Tecta	UTSW	9	42,270,759 (GRCm39)	missense	probably damaging	0.99
R9564:Tecta	UTSW	9	42,249,123 (GRCm39)	missense	probably damaging	0.97
R9592:Tecta	UTSW	9	42,250,238 (GRCm39)	missense	probably damaging	1.00
R9715:Tecta	UTSW	9	42,286,596 (GRCm39)	missense	probably damaging	1.00
Z1176:Tecta	UTSW	9	42,303,390 (GRCm39)	missense	probably damaging	0.99
Z1177:Tecta	UTSW	9	42,286,872 (GRCm39)	missense	probably benign	0.00
Z1177:Tecta	UTSW	9	42,303,366 (GRCm39)	missense	probably damaging	1.00

Predicted Primers

PCR Primer
(F):5'- GCCCAAGAAGAGCAGATGTC -3'
(R):5'- GCAGCTGCCGTCTAATCTATC -3'

Sequencing Primer
(F):5'- TTCTGTGCTTAATCACCCACAAAGG -3'
(R):5'- AGCTGCCGTCTAATCTATCTAACCAC -3'

Posted On

2019-05-13