Mutagenetix > Incidental Mutation

Incidental Mutation 'R0613:Mtor'

54876

Institutional Source

Beutler Lab

Gene Symbol

Mtor

Ensembl Gene

ENSMUSG00000028991

Gene Name

mechanistic target of rapamycin kinase

Synonyms

RAPT1, FKBP-rapamycin-associated protein FRAP, RAFT1, flat, Frap1, 2610315D21Rik

MMRRC Submission

038802-MU

Accession Numbers

Essential gene?

Essential (E-score: 1.000) question?

Stock #

R0613 (G1)

Quality Score

225

Status

Validated

Chromosome

Chromosomal Location

148448611-148557683 bp(+) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

T to C at 148526046 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Tyrosine to Histidine at position 1605 (Y1605H)

Ref Sequence

ENSEMBL: ENSMUSP00000099510 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000103221]

AlphaFold

Q9JLN9

Predicted Effect

possibly damaging
Transcript: ENSMUST00000103221
AA Change: Y1605H

PolyPhen 2 Score 0.953 (Sensitivity: 0.79; Specificity: 0.95)

SMART Domains

Protein: ENSMUSP00000099510
Gene: ENSMUSG00000028991
AA Change: Y1605H

Domain	Start	End	E-Value	Type
low complexity region	7	21	N/A	INTRINSIC
low complexity region	179	191	N/A	INTRINSIC
low complexity region	277	288	N/A	INTRINSIC
low complexity region	774	790	N/A	INTRINSIC
DUF3385	854	1024	1.51e-93	SMART
low complexity region	1279	1300	N/A	INTRINSIC
Pfam:FAT	1513	1908	2.3e-134	PFAM
Rapamycin_bind	2015	2114	7.94e-61	SMART
PI3Kc	2183	2484	8.84e-121	SMART
FATC	2517	2549	2.11e-15	SMART

Meta Mutation Damage Score

0.7691

Coding Region Coverage

1x: 99.4%
3x: 98.9%
10x: 97.6%
20x: 95.3%

Validation Efficiency

100% (72/72)

MGI Phenotype

Strain: 3529989; 4820819; 3512186; 5425404; 3052669
Lethality: E11-E12
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. The ANGPTL7 gene is located in an intron of this gene. [provided by RefSeq, Sep 2008]
PHENOTYPE: Mice homozygous for targeted, gene trap and ENU-induced null alleles exhibit embryonic lethality by E12.5 with abnormal embryogenesis. Mice homozygous for the ENU mutation further exhibit abnormal brain development. [provided by MGI curators]

Allele List at MGI

All alleles(25) : Targeted(12) Gene trapped(12) Chemically induced(1)

Other mutations in this stock

Total: 72 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Acd	A	T	8: 105,700,568 (GRCm38)		probably null	Het
Adcy9	A	G	16: 4,419,539 (GRCm38)	S3P	probably damaging	Het
Adgrl4	T	C	3: 151,543,222 (GRCm38)		probably benign	Het
Aff3	T	C	1: 38,209,923 (GRCm38)	E700G	probably benign	Het
Ahctf1	A	G	1: 179,769,414 (GRCm38)	S56P	probably damaging	Het
Atp12a	T	A	14: 56,374,521 (GRCm38)	I384N	probably damaging	Het
Brca1	A	T	11: 101,508,210 (GRCm38)	S1519T	probably benign	Het
Ccl25	T	C	8: 4,349,850 (GRCm38)	V94A	probably benign	Het
Cep170	T	C	1: 176,774,680 (GRCm38)	T287A	probably benign	Het
Ces1a	A	G	8: 93,025,581 (GRCm38)	S383P	probably benign	Het
Cntnap3	A	T	13: 64,758,414 (GRCm38)	F793I	probably damaging	Het
Ctsm	T	C	13: 61,539,682 (GRCm38)	R89G	probably damaging	Het
Cyp2j12	T	G	4: 96,102,079 (GRCm38)	T417P	probably damaging	Het
D430041D05Rik	G	C	2: 104,167,950 (GRCm38)	P1836R	probably damaging	Het
Edn2	T	A	4: 120,161,864 (GRCm38)		probably null	Het
Emc1	T	A	4: 139,375,072 (GRCm38)		probably benign	Het
Entrep1	T	A	19: 23,986,489 (GRCm38)	N239Y	probably damaging	Het
Fras1	T	C	5: 96,700,488 (GRCm38)		probably benign	Het
Fsip2	A	T	2: 82,993,795 (GRCm38)	D6624V	probably damaging	Het
Gpr107	A	G	2: 31,178,285 (GRCm38)	Y253C	probably damaging	Het
Gpr108	A	G	17: 57,238,174 (GRCm38)		probably benign	Het
Grik1	A	G	16: 88,051,333 (GRCm38)		probably null	Het
Gtf3c1	G	A	7: 125,644,134 (GRCm38)	P1766L	possibly damaging	Het
Gucy2c	A	T	6: 136,760,723 (GRCm38)	N293K	probably damaging	Het
Hps6	C	A	19: 46,003,821 (GRCm38)	P66T	probably benign	Het
Hspa9	A	T	18: 34,947,980 (GRCm38)	V216E	probably damaging	Het
Igsf8	T	A	1: 172,317,589 (GRCm38)	M224K	probably benign	Het
Igsf9b	T	C	9: 27,326,920 (GRCm38)	V569A	probably damaging	Het
Itgb4	A	T	11: 115,993,342 (GRCm38)	I952F	probably damaging	Het
Kcnh4	C	T	11: 100,746,932 (GRCm38)	G633E	probably benign	Het
Khdrbs2	A	G	1: 32,657,522 (GRCm38)	H344R	possibly damaging	Het
Kmo	C	A	1: 175,637,892 (GRCm38)	R71S	probably damaging	Het
Lrrc31	A	G	3: 30,685,035 (GRCm38)		probably benign	Het
Map1b	T	A	13: 99,441,641 (GRCm38)	D168V	probably damaging	Het
Mfsd6	T	C	1: 52,658,696 (GRCm38)		probably benign	Het
Mgst1	G	A	6: 138,156,245 (GRCm38)	G186D	probably damaging	Het
Mrc1	C	T	2: 14,294,819 (GRCm38)	A740V	probably damaging	Het
Mroh2a	G	A	1: 88,243,950 (GRCm38)	R770Q	probably damaging	Het
Ncoa4	T	A	14: 32,176,552 (GRCm38)	L443Q	probably damaging	Het
Nelfa	G	A	5: 33,903,463 (GRCm38)		probably benign	Het
Nepn	T	A	10: 52,401,257 (GRCm38)	L363Q	probably damaging	Het
Nfat5	A	G	8: 107,366,295 (GRCm38)	T630A	possibly damaging	Het
Nipal4	A	T	11: 46,150,384 (GRCm38)	V328E	probably benign	Het
Or11h4b	T	A	14: 50,681,404 (GRCm38)	I77F	probably benign	Het
Or2y1e	T	A	11: 49,327,748 (GRCm38)	S112R	possibly damaging	Het
Or4c122	A	T	2: 89,249,125 (GRCm38)	C178S	probably damaging	Het
Or4d2b	A	T	11: 87,889,227 (GRCm38)	V223E	possibly damaging	Het
Or6c76	T	A	10: 129,776,262 (GRCm38)	M116K	probably damaging	Het
Or8d2	T	A	9: 38,848,613 (GRCm38)	C166*	probably null	Het
Otogl	A	T	10: 107,817,070 (GRCm38)	N1140K	probably damaging	Het
Ppip5k2	A	C	1: 97,752,740 (GRCm38)	Y236*	probably null	Het
Prelid1	C	T	13: 55,324,343 (GRCm38)	R111*	probably null	Het
Prpf8	T	C	11: 75,503,444 (GRCm38)	L1771P	probably damaging	Het
Ptprb	A	T	10: 116,302,325 (GRCm38)	Y378F	possibly damaging	Het
Ptprb	A	G	10: 116,302,378 (GRCm38)	T396A	possibly damaging	Het
Rab3il1	T	C	19: 10,028,364 (GRCm38)	L174P	probably damaging	Het
Rab4a	T	C	8: 123,823,835 (GRCm38)	V18A	possibly damaging	Het
Scn3a	T	A	2: 65,472,284 (GRCm38)	M1273L	possibly damaging	Het
Sdhc	A	T	1: 171,129,844 (GRCm38)	V156E	probably benign	Het
Slco3a1	T	C	7: 74,346,634 (GRCm38)		probably benign	Het
Syne3	T	C	12: 104,958,112 (GRCm38)	T343A	probably benign	Het
Syt11	A	G	3: 88,762,469 (GRCm38)	C39R	probably damaging	Het
Tll2	G	T	19: 41,104,990 (GRCm38)	D462E	probably damaging	Het
Tmem132e	T	A	11: 82,438,338 (GRCm38)	V481D	probably damaging	Het
Tmem161b	C	T	13: 84,251,320 (GRCm38)	L17F	probably damaging	Het
Vmn2r105	T	A	17: 20,208,316 (GRCm38)	I833F	probably damaging	Het
Vstm2a	A	T	11: 16,263,140 (GRCm38)	N175I	probably damaging	Het
Xpnpep1	G	T	19: 53,006,353 (GRCm38)	D238E	probably damaging	Het
Zfp112	G	A	7: 24,127,028 (GRCm38)	G807D	probably benign	Het
Zfp518b	A	T	5: 38,673,603 (GRCm38)	V353E	probably damaging	Het
Zfp69	T	C	4: 120,934,347 (GRCm38)	E39G	probably benign	Het
Zfp865	A	G	7: 5,029,091 (GRCm38)	H25R	possibly damaging	Het

Other mutations in Mtor

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01123:Mtor	APN	4	148,453,037 (GRCm38)	missense	probably benign	0.06
IGL01447:Mtor	APN	4	148,530,757 (GRCm38)	missense	possibly damaging	0.62
IGL01551:Mtor	APN	4	148,472,037 (GRCm38)	missense	probably damaging	0.99
IGL01661:Mtor	APN	4	148,514,851 (GRCm38)	missense	possibly damaging	0.61
IGL01675:Mtor	APN	4	148,484,654 (GRCm38)	missense	probably benign	0.00
IGL01743:Mtor	APN	4	148,530,613 (GRCm38)	splice site	probably benign
IGL02015:Mtor	APN	4	148,540,113 (GRCm38)	nonsense	probably null
IGL02084:Mtor	APN	4	148,470,680 (GRCm38)	missense	probably damaging	0.98
IGL02095:Mtor	APN	4	148,544,541 (GRCm38)	missense	probably damaging	1.00
IGL02129:Mtor	APN	4	148,549,845 (GRCm38)	missense	possibly damaging	0.91
IGL02260:Mtor	APN	4	148,538,301 (GRCm38)	missense	probably damaging	1.00
IGL02329:Mtor	APN	4	148,534,939 (GRCm38)	missense	probably benign	0.16
IGL02440:Mtor	APN	4	148,491,647 (GRCm38)	missense	probably benign	0.04
IGL02440:Mtor	APN	4	148,546,429 (GRCm38)	missense	probably benign	0.24
IGL02449:Mtor	APN	4	148,533,921 (GRCm38)	missense	possibly damaging	0.65
IGL02479:Mtor	APN	4	148,470,584 (GRCm38)	missense	probably damaging	1.00
IGL02904:Mtor	APN	4	148,491,612 (GRCm38)	splice site	probably benign
IGL02904:Mtor	APN	4	148,452,394 (GRCm38)	missense	possibly damaging	0.55
IGL02931:Mtor	APN	4	148,464,964 (GRCm38)	missense	probably benign	0.22
IGL03048:Mtor	APN	4	148,546,390 (GRCm38)	splice site	probably benign
IGL03133:Mtor	APN	4	148,484,319 (GRCm38)	missense	probably benign	0.01
IGL03142:Mtor	APN	4	148,453,899 (GRCm38)	missense	probably benign	0.00
Brushes	UTSW	4	148,463,748 (GRCm38)	missense	probably benign	0.00
Dynamo	UTSW	4	148,462,910 (GRCm38)	missense	probably benign	0.00
engine	UTSW	4	148,556,855 (GRCm38)	splice site	probably null
Erg	UTSW	4	148,545,596 (GRCm38)	missense	probably damaging	1.00
Lindor	UTSW	4	148,454,646 (GRCm38)	missense	probably damaging	1.00
motor	UTSW	4	148,491,360 (GRCm38)	missense	possibly damaging	0.76
R4858_Mtor_211	UTSW	4	148,454,816 (GRCm38)	makesense	probably null
Vigor	UTSW	4	148,538,899 (GRCm38)	missense	probably damaging	1.00
Vim	UTSW	4	148,525,803 (GRCm38)	critical splice donor site	probably null
PIT4519001:Mtor	UTSW	4	148,524,500 (GRCm38)	missense	probably damaging	1.00
R0045:Mtor	UTSW	4	148,464,949 (GRCm38)	missense	probably benign	0.42
R0048:Mtor	UTSW	4	148,538,881 (GRCm38)	nonsense	probably null
R0048:Mtor	UTSW	4	148,538,881 (GRCm38)	nonsense	probably null
R0103:Mtor	UTSW	4	148,533,902 (GRCm38)	missense	probably benign	0.05
R0112:Mtor	UTSW	4	148,480,923 (GRCm38)	missense	probably damaging	1.00
R0137:Mtor	UTSW	4	148,470,624 (GRCm38)	missense	possibly damaging	0.78
R0184:Mtor	UTSW	4	148,464,971 (GRCm38)	missense	probably benign	0.05
R0208:Mtor	UTSW	4	148,464,975 (GRCm38)	missense	probably benign	0.43
R0329:Mtor	UTSW	4	148,484,380 (GRCm38)	missense	probably benign
R0330:Mtor	UTSW	4	148,484,380 (GRCm38)	missense	probably benign
R0365:Mtor	UTSW	4	148,486,050 (GRCm38)	missense	probably benign	0.01
R0537:Mtor	UTSW	4	148,538,360 (GRCm38)	missense	probably damaging	1.00
R0542:Mtor	UTSW	4	148,540,450 (GRCm38)	missense	probably benign	0.02
R0556:Mtor	UTSW	4	148,469,380 (GRCm38)	missense	possibly damaging	0.88
R0646:Mtor	UTSW	4	148,484,354 (GRCm38)	nonsense	probably null
R0710:Mtor	UTSW	4	148,464,391 (GRCm38)	missense	possibly damaging	0.73
R0791:Mtor	UTSW	4	148,462,910 (GRCm38)	missense	probably benign	0.00
R0792:Mtor	UTSW	4	148,462,910 (GRCm38)	missense	probably benign	0.00
R0866:Mtor	UTSW	4	148,486,056 (GRCm38)	missense	probably benign	0.04
R0973:Mtor	UTSW	4	148,550,188 (GRCm38)	missense	probably damaging	1.00
R1027:Mtor	UTSW	4	148,539,999 (GRCm38)	missense	probably benign	0.03
R1028:Mtor	UTSW	4	148,538,830 (GRCm38)	missense	possibly damaging	0.88
R1289:Mtor	UTSW	4	148,470,307 (GRCm38)	missense	probably benign	0.10
R1416:Mtor	UTSW	4	148,491,414 (GRCm38)	nonsense	probably null
R1465:Mtor	UTSW	4	148,525,993 (GRCm38)	splice site	probably benign
R1506:Mtor	UTSW	4	148,536,505 (GRCm38)	splice site	probably benign
R1624:Mtor	UTSW	4	148,547,676 (GRCm38)	missense	probably damaging	1.00
R1695:Mtor	UTSW	4	148,538,907 (GRCm38)	missense	probably benign	0.08
R1771:Mtor	UTSW	4	148,470,624 (GRCm38)	missense	possibly damaging	0.78
R1800:Mtor	UTSW	4	148,462,892 (GRCm38)	missense	probably benign	0.00
R1855:Mtor	UTSW	4	148,553,089 (GRCm38)	missense	probably benign	0.02
R1857:Mtor	UTSW	4	148,480,879 (GRCm38)	missense	probably damaging	1.00
R1867:Mtor	UTSW	4	148,454,632 (GRCm38)	missense	probably damaging	0.97
R1954:Mtor	UTSW	4	148,468,273 (GRCm38)	missense	probably damaging	1.00
R2054:Mtor	UTSW	4	148,466,025 (GRCm38)	missense	probably benign	0.00
R2054:Mtor	UTSW	4	148,462,852 (GRCm38)	missense	probably benign	0.05
R2099:Mtor	UTSW	4	148,550,192 (GRCm38)	nonsense	probably null
R2148:Mtor	UTSW	4	148,456,012 (GRCm38)	missense	possibly damaging	0.56
R2214:Mtor	UTSW	4	148,538,870 (GRCm38)	missense	probably benign	0.39
R2281:Mtor	UTSW	4	148,489,555 (GRCm38)	missense	probably benign	0.02
R2512:Mtor	UTSW	4	148,530,491 (GRCm38)	missense	possibly damaging	0.95
R2870:Mtor	UTSW	4	148,540,030 (GRCm38)	missense	probably benign	0.00
R2870:Mtor	UTSW	4	148,540,030 (GRCm38)	missense	probably benign	0.00
R2871:Mtor	UTSW	4	148,540,030 (GRCm38)	missense	probably benign	0.00
R2871:Mtor	UTSW	4	148,540,030 (GRCm38)	missense	probably benign	0.00
R2872:Mtor	UTSW	4	148,540,030 (GRCm38)	missense	probably benign	0.00
R2872:Mtor	UTSW	4	148,540,030 (GRCm38)	missense	probably benign	0.00
R2873:Mtor	UTSW	4	148,540,030 (GRCm38)	missense	probably benign	0.00
R4032:Mtor	UTSW	4	148,536,752 (GRCm38)	missense	probably benign	0.03
R4073:Mtor	UTSW	4	148,549,375 (GRCm38)	missense	probably damaging	0.99
R4273:Mtor	UTSW	4	148,550,152 (GRCm38)	missense	probably benign	0.21
R4611:Mtor	UTSW	4	148,486,119 (GRCm38)	missense	probably benign	0.03
R4858:Mtor	UTSW	4	148,454,816 (GRCm38)	makesense	probably null
R4942:Mtor	UTSW	4	148,472,142 (GRCm38)	missense	probably benign	0.03
R4967:Mtor	UTSW	4	148,491,360 (GRCm38)	missense	possibly damaging	0.76
R4995:Mtor	UTSW	4	148,525,752 (GRCm38)	missense	probably damaging	1.00
R5054:Mtor	UTSW	4	148,556,855 (GRCm38)	splice site	probably null
R5215:Mtor	UTSW	4	148,453,983 (GRCm38)	missense	probably benign
R5249:Mtor	UTSW	4	148,463,732 (GRCm38)	missense	probably damaging	1.00
R5289:Mtor	UTSW	4	148,466,092 (GRCm38)	missense	possibly damaging	0.88
R5365:Mtor	UTSW	4	148,550,130 (GRCm38)	missense	probably damaging	0.99
R5498:Mtor	UTSW	4	148,540,364 (GRCm38)	missense	possibly damaging	0.71
R5514:Mtor	UTSW	4	148,546,444 (GRCm38)	missense	probably damaging	1.00
R5540:Mtor	UTSW	4	148,454,708 (GRCm38)	missense	probably benign	0.01
R5600:Mtor	UTSW	4	148,491,470 (GRCm38)	missense	probably damaging	1.00
R5615:Mtor	UTSW	4	148,538,276 (GRCm38)	missense	possibly damaging	0.95
R5632:Mtor	UTSW	4	148,469,006 (GRCm38)	missense	possibly damaging	0.94
R5641:Mtor	UTSW	4	148,546,425 (GRCm38)	missense	probably damaging	0.98
R5834:Mtor	UTSW	4	148,536,536 (GRCm38)	missense	possibly damaging	0.95
R5984:Mtor	UTSW	4	148,538,827 (GRCm38)	missense	probably benign	0.02
R6056:Mtor	UTSW	4	148,537,435 (GRCm38)	missense	probably benign	0.00
R6225:Mtor	UTSW	4	148,521,337 (GRCm38)	missense	probably benign	0.04
R6262:Mtor	UTSW	4	148,526,095 (GRCm38)	missense	possibly damaging	0.46
R6335:Mtor	UTSW	4	148,465,927 (GRCm38)	missense	probably damaging	1.00
R6479:Mtor	UTSW	4	148,551,000 (GRCm38)	missense	probably benign	0.16
R6543:Mtor	UTSW	4	148,545,596 (GRCm38)	missense	probably damaging	1.00
R6711:Mtor	UTSW	4	148,452,367 (GRCm38)	missense	possibly damaging	0.49
R6715:Mtor	UTSW	4	148,538,547 (GRCm38)	missense	probably benign	0.00
R6744:Mtor	UTSW	4	148,458,655 (GRCm38)	missense	probably benign	0.01
R6748:Mtor	UTSW	4	148,550,184 (GRCm38)	missense	probably damaging	1.00
R6762:Mtor	UTSW	4	148,538,481 (GRCm38)	missense	possibly damaging	0.47
R6836:Mtor	UTSW	4	148,489,498 (GRCm38)	missense	possibly damaging	0.94
R6948:Mtor	UTSW	4	148,536,752 (GRCm38)	missense	probably benign	0.12
R6979:Mtor	UTSW	4	148,524,473 (GRCm38)	missense	possibly damaging	0.60
R6992:Mtor	UTSW	4	148,464,475 (GRCm38)	missense	probably benign
R7271:Mtor	UTSW	4	148,546,485 (GRCm38)	missense	possibly damaging	0.70
R7423:Mtor	UTSW	4	148,556,344 (GRCm38)	missense	possibly damaging	0.77
R7434:Mtor	UTSW	4	148,464,959 (GRCm38)	missense	probably benign	0.39
R7619:Mtor	UTSW	4	148,462,795 (GRCm38)	missense	probably damaging	0.98
R7634:Mtor	UTSW	4	148,452,350 (GRCm38)	missense	possibly damaging	0.53
R7697:Mtor	UTSW	4	148,540,308 (GRCm38)	nonsense	probably null
R7737:Mtor	UTSW	4	148,538,738 (GRCm38)	missense	possibly damaging	0.95
R7791:Mtor	UTSW	4	148,462,940 (GRCm38)	missense	probably benign	0.00
R7858:Mtor	UTSW	4	148,454,646 (GRCm38)	missense	probably damaging	1.00
R8035:Mtor	UTSW	4	148,546,399 (GRCm38)	missense	probably benign	0.29
R8076:Mtor	UTSW	4	148,525,803 (GRCm38)	critical splice donor site	probably null
R8078:Mtor	UTSW	4	148,468,287 (GRCm38)	missense	probably benign
R8928:Mtor	UTSW	4	148,538,899 (GRCm38)	missense	probably damaging	1.00
R9040:Mtor	UTSW	4	148,463,748 (GRCm38)	missense	probably benign	0.00
R9116:Mtor	UTSW	4	148,552,741 (GRCm38)	missense	probably benign
R9284:Mtor	UTSW	4	148,459,080 (GRCm38)	missense	probably benign	0.03
R9310:Mtor	UTSW	4	148,469,377 (GRCm38)	missense	probably benign	0.03
R9374:Mtor	UTSW	4	148,514,940 (GRCm38)	missense	probably damaging	1.00
R9417:Mtor	UTSW	4	148,538,319 (GRCm38)	nonsense	probably null
R9465:Mtor	UTSW	4	148,540,382 (GRCm38)	missense	possibly damaging	0.92
R9492:Mtor	UTSW	4	148,484,344 (GRCm38)	missense	probably damaging	1.00
R9499:Mtor	UTSW	4	148,514,940 (GRCm38)	missense	probably damaging	1.00
R9516:Mtor	UTSW	4	148,484,646 (GRCm38)	missense	probably benign	0.23
R9600:Mtor	UTSW	4	148,547,635 (GRCm38)	missense	possibly damaging	0.82
R9622:Mtor	UTSW	4	148,483,712 (GRCm38)	missense	probably damaging	0.99
X0025:Mtor	UTSW	4	148,530,714 (GRCm38)	missense	probably benign	0.09
Z1176:Mtor	UTSW	4	148,550,130 (GRCm38)	missense	possibly damaging	0.69
Z1176:Mtor	UTSW	4	148,550,125 (GRCm38)	missense	probably benign	0.08

Predicted Primers

PCR Primer
(F):5'- GCACGTTGTCAGAATCTACAGCCC -3'
(R):5'- CAGTGAGTCCCAGGTTACCATTTCC -3'

Sequencing Primer
(F):5'- TGTCAGAATCTACAGCCCTAATGAG -3'
(R):5'- ACCATTTCCAAGTGGAGGGTC -3'

Posted On

2013-07-11