Incidental Mutation 'R7073:Lrrc7'
| ID |
549014 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Lrrc7
|
| Ensembl Gene |
ENSMUSG00000028176 |
| Gene Name |
leucine rich repeat containing 7 |
| Synonyms |
densin |
| MMRRC Submission |
045169-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably essential
(E-score: 0.798)
|
| Stock # |
R7073 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
3 |
| Chromosomal Location |
157788528-158267858 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
C to T
at 157832884 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Glycine to Arginine
at position 1425
(G1425R)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000142498
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000106044]
[ENSMUST00000199890]
[ENSMUST00000200137]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000106044
AA Change: G1472R
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000101659
Gene: ENSMUSG00000028176
AA Change: G1472R
| Domain | Start | End | E-Value | Type |
|---|
|
LRR
|
53 |
73 |
3.65e0 |
SMART |
|
LRR
|
96 |
118 |
2.2e1 |
SMART |
|
LRR
|
142 |
164 |
4.21e1 |
SMART |
|
LRR
|
165 |
187 |
7.36e0 |
SMART |
|
LRR
|
188 |
210 |
7.05e-1 |
SMART |
|
LRR
|
211 |
233 |
3.09e1 |
SMART |
|
LRR
|
234 |
257 |
4.21e1 |
SMART |
|
LRR
|
258 |
279 |
2.61e2 |
SMART |
|
LRR
|
280 |
303 |
3.52e-1 |
SMART |
|
LRR
|
326 |
349 |
1.99e0 |
SMART |
|
LRR
|
372 |
394 |
2.63e0 |
SMART |
|
low complexity region
|
466 |
476 |
N/A |
INTRINSIC |
|
low complexity region
|
692 |
705 |
N/A |
INTRINSIC |
|
Blast:PDZ
|
708 |
736 |
1e-5 |
BLAST |
|
low complexity region
|
787 |
797 |
N/A |
INTRINSIC |
|
low complexity region
|
864 |
878 |
N/A |
INTRINSIC |
|
Blast:PDZ
|
1349 |
1378 |
2e-11 |
BLAST |
|
PDZ
|
1460 |
1540 |
1.33e-19 |
SMART |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000199890
AA Change: G1385R
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000142440
Gene: ENSMUSG00000028176
AA Change: G1385R
| Domain | Start | End | E-Value | Type |
|---|
|
LRR
|
53 |
73 |
3.65e0 |
SMART |
|
LRR
|
96 |
118 |
2.2e1 |
SMART |
|
LRR
|
142 |
164 |
4.21e1 |
SMART |
|
LRR
|
165 |
187 |
7.36e0 |
SMART |
|
LRR
|
188 |
210 |
7.05e-1 |
SMART |
|
LRR
|
211 |
233 |
3.09e1 |
SMART |
|
LRR
|
234 |
257 |
4.21e1 |
SMART |
|
LRR
|
258 |
279 |
2.61e2 |
SMART |
|
LRR
|
280 |
303 |
3.52e-1 |
SMART |
|
LRR
|
326 |
349 |
1.99e0 |
SMART |
|
LRR
|
372 |
394 |
2.63e0 |
SMART |
|
low complexity region
|
466 |
476 |
N/A |
INTRINSIC |
|
low complexity region
|
692 |
705 |
N/A |
INTRINSIC |
|
Blast:PDZ
|
708 |
736 |
9e-6 |
BLAST |
|
low complexity region
|
787 |
797 |
N/A |
INTRINSIC |
|
low complexity region
|
864 |
878 |
N/A |
INTRINSIC |
|
Blast:PDZ
|
1328 |
1364 |
1e-15 |
BLAST |
|
low complexity region
|
1374 |
1387 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000200137
AA Change: G1425R
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000142498
Gene: ENSMUSG00000028176
AA Change: G1425R
| Domain | Start | End | E-Value | Type |
|---|
|
LRR
|
52 |
69 |
7.6e-1 |
SMART |
|
LRR
|
73 |
92 |
4.2e-1 |
SMART |
|
LRR
|
96 |
115 |
3.4e-1 |
SMART |
|
LRR
|
142 |
164 |
1.8e-1 |
SMART |
|
LRR
|
165 |
184 |
1.5e-1 |
SMART |
|
LRR
|
188 |
207 |
2e-2 |
SMART |
|
LRR
|
211 |
233 |
1.3e-1 |
SMART |
|
LRR
|
234 |
257 |
1.7e-1 |
SMART |
|
LRR
|
257 |
276 |
1e0 |
SMART |
|
LRR
|
280 |
299 |
3.1e-2 |
SMART |
|
LRR
|
303 |
322 |
6.6e-1 |
SMART |
|
LRR
|
326 |
345 |
2.1e-1 |
SMART |
|
LRR
|
372 |
391 |
1.2e-1 |
SMART |
|
low complexity region
|
466 |
476 |
N/A |
INTRINSIC |
|
low complexity region
|
692 |
705 |
N/A |
INTRINSIC |
|
Blast:PDZ
|
708 |
736 |
1e-5 |
BLAST |
|
low complexity region
|
787 |
797 |
N/A |
INTRINSIC |
|
low complexity region
|
864 |
878 |
N/A |
INTRINSIC |
|
Blast:PDZ
|
1302 |
1331 |
2e-11 |
BLAST |
|
PDZ
|
1413 |
1493 |
6.4e-22 |
SMART |
|
| Predicted Effect |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.7%
- 20x: 99.0%
|
| Validation Efficiency |
|
| MGI Phenotype |
PHENOTYPE: Mice homozygous for a knock-out allele exhibit limb grasping, reduced long term depression, increased anxiety, increased aggression towards other mice, impaired spatial memory, decreased prepulse inhibition, decreased nesting building behavior, and abnormal dendritic spines. [provided by MGI curators]
|
| Allele List at MGI |
All alleles(2) : Gene trapped(2) |
| Other mutations in this stock |
Total: 80 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Adgrv1 |
T |
G |
13: 81,709,593 (GRCm39) |
E1133D |
probably damaging |
Het |
| Ankrd13b |
A |
T |
11: 77,363,335 (GRCm39) |
D505E |
probably benign |
Het |
| Ano1 |
C |
T |
7: 144,192,289 (GRCm39) |
E361K |
probably damaging |
Het |
| Arap3 |
T |
A |
18: 38,107,495 (GRCm39) |
K1341* |
probably null |
Het |
| Arhgef17 |
A |
C |
7: 100,579,198 (GRCm39) |
Y583* |
probably null |
Het |
| Ash1l |
G |
A |
3: 88,892,647 (GRCm39) |
E1509K |
probably damaging |
Het |
| B430305J03Rik |
T |
G |
3: 61,271,681 (GRCm39) |
R21S |
unknown |
Het |
| Bbof1 |
A |
G |
12: 84,473,609 (GRCm39) |
E313G |
probably damaging |
Het |
| Catsperb |
C |
T |
12: 101,475,497 (GRCm39) |
T347I |
probably benign |
Het |
| Ccdc24 |
G |
T |
4: 117,729,201 (GRCm39) |
A92D |
probably damaging |
Het |
| Ccdc63 |
T |
C |
5: 122,249,073 (GRCm39) |
T419A |
probably benign |
Het |
| Ccdc7a |
C |
T |
8: 129,618,866 (GRCm39) |
V893I |
possibly damaging |
Het |
| Ccdc88b |
G |
T |
19: 6,831,330 (GRCm39) |
D537E |
probably benign |
Het |
| Cd276 |
T |
C |
9: 58,444,615 (GRCm39) |
S119G |
probably damaging |
Het |
| Cdkn3 |
T |
C |
14: 47,004,647 (GRCm39) |
Y70H |
possibly damaging |
Het |
| Cdo1 |
G |
A |
18: 46,861,266 (GRCm39) |
|
probably benign |
Het |
| Cdr2 |
A |
T |
7: 120,581,247 (GRCm39) |
F10Y |
probably damaging |
Het |
| Cep290 |
A |
T |
10: 100,374,865 (GRCm39) |
K1370N |
possibly damaging |
Het |
| Crb1 |
T |
A |
1: 139,176,049 (GRCm39) |
I645F |
probably damaging |
Het |
| Cul7 |
T |
C |
17: 46,969,657 (GRCm39) |
W975R |
probably damaging |
Het |
| Ddx39b |
A |
C |
17: 35,471,826 (GRCm39) |
E324A |
probably benign |
Het |
| Diaph1 |
T |
G |
18: 38,022,867 (GRCm39) |
|
probably null |
Het |
| Dnah2 |
G |
A |
11: 69,321,318 (GRCm39) |
R3917* |
probably null |
Het |
| Dnph1 |
T |
A |
17: 46,807,815 (GRCm39) |
L27Q |
probably damaging |
Het |
| Duox2 |
A |
G |
2: 122,119,788 (GRCm39) |
F880S |
probably damaging |
Het |
| Ell2 |
C |
A |
13: 75,910,006 (GRCm39) |
L119M |
probably damaging |
Het |
| Enpep |
A |
T |
3: 129,106,319 (GRCm39) |
Y302* |
probably null |
Het |
| Ergic2 |
G |
T |
6: 148,096,707 (GRCm39) |
H186Q |
probably damaging |
Het |
| Fam83b |
T |
C |
9: 76,453,031 (GRCm39) |
D12G |
probably benign |
Het |
| Fbxw16 |
A |
T |
9: 109,270,123 (GRCm39) |
V206D |
probably damaging |
Het |
| Fhod1 |
A |
T |
8: 106,063,771 (GRCm39) |
V278D |
unknown |
Het |
| Gba2 |
G |
C |
4: 43,573,753 (GRCm39) |
Q180E |
probably damaging |
Het |
| Grhl3 |
G |
A |
4: 135,300,723 (GRCm39) |
L5F |
probably benign |
Het |
| H2-T15 |
A |
T |
17: 36,369,235 (GRCm39) |
C7S |
unknown |
Het |
| Ifit1bl1 |
C |
T |
19: 34,576,667 (GRCm39) |
|
probably null |
Het |
| Ift57 |
A |
G |
16: 49,584,230 (GRCm39) |
T413A |
probably benign |
Het |
| Itga2 |
A |
G |
13: 114,996,149 (GRCm39) |
F714S |
probably damaging |
Het |
| Jmy |
A |
G |
13: 93,577,841 (GRCm39) |
S776P |
probably benign |
Het |
| Kbtbd8 |
G |
A |
6: 95,098,814 (GRCm39) |
A108T |
probably damaging |
Het |
| Kpna6 |
G |
A |
4: 129,548,139 (GRCm39) |
A230V |
probably damaging |
Het |
| Lrfn1 |
C |
T |
7: 28,159,397 (GRCm39) |
L439F |
possibly damaging |
Het |
| Lrrc1 |
T |
A |
9: 77,375,847 (GRCm39) |
I147F |
probably benign |
Het |
| Madd |
T |
A |
2: 90,992,854 (GRCm39) |
I1022F |
probably damaging |
Het |
| Map2k2 |
A |
T |
10: 80,942,017 (GRCm39) |
T13S |
probably benign |
Het |
| Mdc1 |
G |
A |
17: 36,164,960 (GRCm39) |
V1459I |
probably benign |
Het |
| Mdh1b |
G |
A |
1: 63,760,719 (GRCm39) |
T114M |
probably damaging |
Het |
| Mfsd2a |
T |
C |
4: 122,845,088 (GRCm39) |
I208V |
possibly damaging |
Het |
| Mmrn1 |
T |
A |
6: 60,965,411 (GRCm39) |
D1147E |
probably damaging |
Het |
| Nbeal2 |
T |
A |
9: 110,455,177 (GRCm39) |
I2574F |
probably damaging |
Het |
| Nr1d1 |
T |
G |
11: 98,662,892 (GRCm39) |
S34R |
probably damaging |
Het |
| Nr3c1 |
A |
T |
18: 39,619,449 (GRCm39) |
D279E |
probably benign |
Het |
| Nrde2 |
T |
C |
12: 100,098,747 (GRCm39) |
D640G |
probably benign |
Het |
| Odf4 |
A |
G |
11: 68,817,514 (GRCm39) |
L58P |
probably damaging |
Het |
| Or4k41 |
A |
T |
2: 111,279,631 (GRCm39) |
I49F |
probably benign |
Het |
| Or4p22 |
A |
T |
2: 88,317,651 (GRCm39) |
I192F |
probably benign |
Het |
| Otud6b |
A |
C |
4: 14,811,743 (GRCm39) |
M300R |
probably damaging |
Het |
| Pamr1 |
T |
A |
2: 102,471,280 (GRCm39) |
D534E |
probably benign |
Het |
| Pcdh7 |
T |
A |
5: 57,878,299 (GRCm39) |
V618E |
probably benign |
Het |
| Pcgf6 |
A |
C |
19: 47,031,226 (GRCm39) |
N266K |
possibly damaging |
Het |
| Plcz1 |
A |
T |
6: 139,968,849 (GRCm39) |
Y196* |
probably null |
Het |
| Plxna1 |
A |
T |
6: 89,334,311 (GRCm39) |
L106Q |
probably damaging |
Het |
| Qrich2 |
G |
A |
11: 116,337,701 (GRCm39) |
A184V |
probably damaging |
Het |
| Rimkla |
A |
G |
4: 119,325,275 (GRCm39) |
L378S |
probably benign |
Het |
| Rufy1 |
G |
T |
11: 50,295,290 (GRCm39) |
H472Q |
probably benign |
Het |
| Samd7 |
T |
A |
3: 30,810,631 (GRCm39) |
M216K |
probably benign |
Het |
| Samd9l |
A |
T |
6: 3,375,856 (GRCm39) |
Y468* |
probably null |
Het |
| Scn2a |
T |
G |
2: 65,558,787 (GRCm39) |
L1194R |
probably benign |
Het |
| Sgo2a |
T |
A |
1: 58,056,944 (GRCm39) |
S1043T |
possibly damaging |
Het |
| Slc6a17 |
G |
T |
3: 107,378,755 (GRCm39) |
H642Q |
probably benign |
Het |
| Smox |
C |
T |
2: 131,364,031 (GRCm39) |
A45V |
possibly damaging |
Het |
| St6galnac3 |
T |
A |
3: 153,117,274 (GRCm39) |
T150S |
possibly damaging |
Het |
| Strip2 |
T |
A |
6: 29,941,911 (GRCm39) |
I627N |
possibly damaging |
Het |
| Sv2c |
A |
T |
13: 96,224,758 (GRCm39) |
C184S |
probably damaging |
Het |
| Tm7sf2 |
A |
T |
19: 6,116,527 (GRCm39) |
|
probably null |
Het |
| Ttc28 |
T |
C |
5: 111,371,282 (GRCm39) |
I608T |
possibly damaging |
Het |
| Vmn1r183 |
T |
G |
7: 23,754,926 (GRCm39) |
L243R |
probably damaging |
Het |
| Vmn1r68 |
T |
C |
7: 10,261,778 (GRCm39) |
T107A |
probably benign |
Het |
| Vnn3 |
G |
A |
10: 23,740,311 (GRCm39) |
G205R |
probably damaging |
Het |
| Zfp516 |
T |
A |
18: 83,006,325 (GRCm39) |
|
probably null |
Het |
| Zpbp2 |
A |
G |
11: 98,443,335 (GRCm39) |
D56G |
probably damaging |
Het |
|
| Other mutations in Lrrc7 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00594:Lrrc7
|
APN |
3 |
157,892,647 (GRCm39) |
missense |
probably benign |
0.07 |
|
IGL00644:Lrrc7
|
APN |
3 |
157,908,005 (GRCm39) |
nonsense |
probably null |
|
|
IGL00822:Lrrc7
|
APN |
3 |
157,891,111 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL00927:Lrrc7
|
APN |
3 |
157,866,727 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
IGL00946:Lrrc7
|
APN |
3 |
157,866,993 (GRCm39) |
missense |
probably benign |
0.07 |
|
IGL00948:Lrrc7
|
APN |
3 |
157,867,194 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01838:Lrrc7
|
APN |
3 |
157,891,100 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01874:Lrrc7
|
APN |
3 |
157,946,080 (GRCm39) |
splice site |
probably benign |
|
|
IGL02514:Lrrc7
|
APN |
3 |
157,865,929 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL02545:Lrrc7
|
APN |
3 |
157,891,011 (GRCm39) |
splice site |
probably benign |
|
|
IGL02665:Lrrc7
|
APN |
3 |
157,866,742 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL03129:Lrrc7
|
APN |
3 |
157,866,696 (GRCm39) |
missense |
probably benign |
0.02 |
|
N/A:Lrrc7
|
UTSW |
3 |
157,865,977 (GRCm39) |
missense |
probably benign |
|
|
R0021:Lrrc7
|
UTSW |
3 |
157,866,298 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0041:Lrrc7
|
UTSW |
3 |
157,869,897 (GRCm39) |
splice site |
probably benign |
|
|
R0255:Lrrc7
|
UTSW |
3 |
157,866,475 (GRCm39) |
nonsense |
probably null |
|
|
R0278:Lrrc7
|
UTSW |
3 |
157,885,432 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R0409:Lrrc7
|
UTSW |
3 |
157,867,063 (GRCm39) |
missense |
possibly damaging |
0.59 |
|
R0612:Lrrc7
|
UTSW |
3 |
157,869,990 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0866:Lrrc7
|
UTSW |
3 |
157,869,903 (GRCm39) |
splice site |
probably benign |
|
|
R1077:Lrrc7
|
UTSW |
3 |
157,866,780 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1103:Lrrc7
|
UTSW |
3 |
157,854,343 (GRCm39) |
splice site |
probably benign |
|
|
R1157:Lrrc7
|
UTSW |
3 |
157,865,892 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1187:Lrrc7
|
UTSW |
3 |
157,866,039 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1301:Lrrc7
|
UTSW |
3 |
157,840,968 (GRCm39) |
missense |
probably benign |
0.20 |
|
R1433:Lrrc7
|
UTSW |
3 |
157,882,943 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1450:Lrrc7
|
UTSW |
3 |
157,892,681 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
R1595:Lrrc7
|
UTSW |
3 |
157,882,914 (GRCm39) |
nonsense |
probably null |
|
|
R1659:Lrrc7
|
UTSW |
3 |
157,867,045 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1693:Lrrc7
|
UTSW |
3 |
157,790,170 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R1774:Lrrc7
|
UTSW |
3 |
157,865,929 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R2273:Lrrc7
|
UTSW |
3 |
157,892,696 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2276:Lrrc7
|
UTSW |
3 |
157,885,429 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2302:Lrrc7
|
UTSW |
3 |
157,840,881 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2326:Lrrc7
|
UTSW |
3 |
157,876,298 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2371:Lrrc7
|
UTSW |
3 |
157,866,697 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2383:Lrrc7
|
UTSW |
3 |
157,869,593 (GRCm39) |
missense |
probably benign |
|
|
R2679:Lrrc7
|
UTSW |
3 |
157,880,745 (GRCm39) |
nonsense |
probably null |
|
|
R2698:Lrrc7
|
UTSW |
3 |
157,841,028 (GRCm39) |
missense |
probably benign |
0.22 |
|
R2858:Lrrc7
|
UTSW |
3 |
157,867,362 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3758:Lrrc7
|
UTSW |
3 |
157,869,602 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3791:Lrrc7
|
UTSW |
3 |
157,869,593 (GRCm39) |
missense |
probably benign |
|
|
R3805:Lrrc7
|
UTSW |
3 |
157,891,130 (GRCm39) |
missense |
probably benign |
0.10 |
|
R3806:Lrrc7
|
UTSW |
3 |
157,891,130 (GRCm39) |
missense |
probably benign |
0.10 |
|
R3807:Lrrc7
|
UTSW |
3 |
157,891,130 (GRCm39) |
missense |
probably benign |
0.10 |
|
R3892:Lrrc7
|
UTSW |
3 |
157,866,333 (GRCm39) |
missense |
probably benign |
0.08 |
|
R3912:Lrrc7
|
UTSW |
3 |
157,997,589 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3913:Lrrc7
|
UTSW |
3 |
157,997,589 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3963:Lrrc7
|
UTSW |
3 |
157,866,042 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4665:Lrrc7
|
UTSW |
3 |
158,024,045 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R4666:Lrrc7
|
UTSW |
3 |
158,024,045 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R4671:Lrrc7
|
UTSW |
3 |
157,908,132 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R4688:Lrrc7
|
UTSW |
3 |
157,854,242 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4725:Lrrc7
|
UTSW |
3 |
158,024,045 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R4726:Lrrc7
|
UTSW |
3 |
158,024,045 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R4728:Lrrc7
|
UTSW |
3 |
158,024,045 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R4783:Lrrc7
|
UTSW |
3 |
157,832,850 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4867:Lrrc7
|
UTSW |
3 |
157,866,642 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4907:Lrrc7
|
UTSW |
3 |
157,866,877 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5032:Lrrc7
|
UTSW |
3 |
157,887,217 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R5107:Lrrc7
|
UTSW |
3 |
157,867,533 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5295:Lrrc7
|
UTSW |
3 |
157,876,376 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5348:Lrrc7
|
UTSW |
3 |
157,880,963 (GRCm39) |
missense |
probably benign |
0.02 |
|
R5468:Lrrc7
|
UTSW |
3 |
158,024,073 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5778:Lrrc7
|
UTSW |
3 |
157,876,380 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5897:Lrrc7
|
UTSW |
3 |
157,869,990 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6179:Lrrc7
|
UTSW |
3 |
158,059,069 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6312:Lrrc7
|
UTSW |
3 |
157,866,246 (GRCm39) |
missense |
probably benign |
0.04 |
|
R6313:Lrrc7
|
UTSW |
3 |
157,866,373 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6366:Lrrc7
|
UTSW |
3 |
157,841,012 (GRCm39) |
missense |
probably benign |
0.04 |
|
R6389:Lrrc7
|
UTSW |
3 |
157,891,063 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6638:Lrrc7
|
UTSW |
3 |
157,840,940 (GRCm39) |
missense |
probably benign |
0.20 |
|
R6956:Lrrc7
|
UTSW |
3 |
157,994,668 (GRCm39) |
missense |
probably benign |
0.02 |
|
R6969:Lrrc7
|
UTSW |
3 |
157,862,550 (GRCm39) |
missense |
probably benign |
0.19 |
|
R7313:Lrrc7
|
UTSW |
3 |
157,866,111 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7365:Lrrc7
|
UTSW |
3 |
157,903,798 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7398:Lrrc7
|
UTSW |
3 |
157,997,595 (GRCm39) |
nonsense |
probably null |
|
|
R7403:Lrrc7
|
UTSW |
3 |
157,854,311 (GRCm39) |
nonsense |
probably null |
|
|
R7407:Lrrc7
|
UTSW |
3 |
157,840,878 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7427:Lrrc7
|
UTSW |
3 |
157,903,778 (GRCm39) |
missense |
probably benign |
0.06 |
|
R7453:Lrrc7
|
UTSW |
3 |
157,891,046 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7461:Lrrc7
|
UTSW |
3 |
157,892,657 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7807:Lrrc7
|
UTSW |
3 |
157,866,124 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7872:Lrrc7
|
UTSW |
3 |
158,059,099 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8215:Lrrc7
|
UTSW |
3 |
157,915,387 (GRCm39) |
missense |
probably benign |
|
|
R8367:Lrrc7
|
UTSW |
3 |
157,908,007 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R8867:Lrrc7
|
UTSW |
3 |
157,867,521 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8880:Lrrc7
|
UTSW |
3 |
157,867,381 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8941:Lrrc7
|
UTSW |
3 |
157,869,593 (GRCm39) |
missense |
probably benign |
|
|
R8958:Lrrc7
|
UTSW |
3 |
157,946,138 (GRCm39) |
missense |
probably benign |
0.02 |
|
R9068:Lrrc7
|
UTSW |
3 |
157,946,138 (GRCm39) |
missense |
probably benign |
0.02 |
|
R9069:Lrrc7
|
UTSW |
3 |
157,946,138 (GRCm39) |
missense |
probably benign |
0.02 |
|
R9180:Lrrc7
|
UTSW |
3 |
157,867,011 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
R9193:Lrrc7
|
UTSW |
3 |
158,059,011 (GRCm39) |
nonsense |
probably null |
|
|
R9309:Lrrc7
|
UTSW |
3 |
157,915,361 (GRCm39) |
nonsense |
probably null |
|
|
R9418:Lrrc7
|
UTSW |
3 |
157,908,023 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R9474:Lrrc7
|
UTSW |
3 |
157,841,028 (GRCm39) |
missense |
probably benign |
0.22 |
|
R9515:Lrrc7
|
UTSW |
3 |
157,867,105 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9635:Lrrc7
|
UTSW |
3 |
157,946,138 (GRCm39) |
missense |
probably benign |
0.02 |
|
R9639:Lrrc7
|
UTSW |
3 |
157,946,138 (GRCm39) |
missense |
probably benign |
0.02 |
|
R9682:Lrrc7
|
UTSW |
3 |
157,882,954 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R9731:Lrrc7
|
UTSW |
3 |
157,880,888 (GRCm39) |
missense |
probably benign |
|
|
| Predicted Primers |
PCR Primer
(F):5'- ACAGACTCGTTTCAGCTTCTG -3'
(R):5'- AGGCATAGAGAGACATTACCCC -3'
Sequencing Primer
(F):5'- AGACTCGTTTCAGCTTCTGTCTGG -3'
(R):5'- GTTCTGTGTGAGGATAGAAA -3'
|
| Posted On |
2019-05-15 |
Incidental Mutation