Incidental Mutation 'R7078:Prrc2b'
| ID |
549314 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Prrc2b
|
| Ensembl Gene |
ENSMUSG00000039262 |
| Gene Name |
proline-rich coiled-coil 2B |
| Synonyms |
5830434P21Rik, Bat2l |
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R7078 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
2 |
| Chromosomal Location |
32041094-32124549 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 32103531 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Aspartic acid to Valine
at position 1003
(D1003V)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000064892
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000036691]
[ENSMUST00000069817]
|
| AlphaFold |
Q7TPM1 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000036691
|
| SMART Domains |
Protein: ENSMUSP00000035734
Gene: ENSMUSG00000039262
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:BAT2_N
|
1 |
194 |
2.7e-85 |
PFAM |
|
low complexity region
|
359 |
374 |
N/A |
INTRINSIC |
|
low complexity region
|
388 |
394 |
N/A |
INTRINSIC |
|
low complexity region
|
413 |
424 |
N/A |
INTRINSIC |
|
coiled coil region
|
494 |
544 |
N/A |
INTRINSIC |
|
low complexity region
|
600 |
621 |
N/A |
INTRINSIC |
|
low complexity region
|
638 |
656 |
N/A |
INTRINSIC |
|
low complexity region
|
885 |
900 |
N/A |
INTRINSIC |
|
low complexity region
|
992 |
1007 |
N/A |
INTRINSIC |
|
low complexity region
|
1112 |
1126 |
N/A |
INTRINSIC |
|
low complexity region
|
1218 |
1233 |
N/A |
INTRINSIC |
|
low complexity region
|
1257 |
1275 |
N/A |
INTRINSIC |
|
low complexity region
|
1402 |
1421 |
N/A |
INTRINSIC |
|
low complexity region
|
1425 |
1437 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000069817
AA Change: D1003V
PolyPhen 2
Score 0.006 (Sensitivity: 0.97; Specificity: 0.75)
|
| SMART Domains |
Protein: ENSMUSP00000064892
Gene: ENSMUSG00000039262
AA Change: D1003V
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:BAT2_N
|
1 |
191 |
3.1e-65 |
PFAM |
|
low complexity region
|
359 |
374 |
N/A |
INTRINSIC |
|
low complexity region
|
388 |
394 |
N/A |
INTRINSIC |
|
low complexity region
|
413 |
424 |
N/A |
INTRINSIC |
|
coiled coil region
|
494 |
544 |
N/A |
INTRINSIC |
|
low complexity region
|
600 |
621 |
N/A |
INTRINSIC |
|
low complexity region
|
638 |
656 |
N/A |
INTRINSIC |
|
low complexity region
|
960 |
977 |
N/A |
INTRINSIC |
|
low complexity region
|
1004 |
1018 |
N/A |
INTRINSIC |
|
low complexity region
|
1070 |
1094 |
N/A |
INTRINSIC |
|
low complexity region
|
1307 |
1325 |
N/A |
INTRINSIC |
|
low complexity region
|
1388 |
1401 |
N/A |
INTRINSIC |
|
low complexity region
|
1413 |
1426 |
N/A |
INTRINSIC |
|
low complexity region
|
1572 |
1587 |
N/A |
INTRINSIC |
|
low complexity region
|
1678 |
1693 |
N/A |
INTRINSIC |
|
low complexity region
|
1798 |
1812 |
N/A |
INTRINSIC |
|
low complexity region
|
1904 |
1919 |
N/A |
INTRINSIC |
|
low complexity region
|
1943 |
1961 |
N/A |
INTRINSIC |
|
low complexity region
|
2088 |
2107 |
N/A |
INTRINSIC |
|
low complexity region
|
2111 |
2123 |
N/A |
INTRINSIC |
|
low complexity region
|
2161 |
2174 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000128936
|
| SMART Domains |
Protein: ENSMUSP00000121664
Gene: ENSMUSG00000039262
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
53 |
68 |
N/A |
INTRINSIC |
|
low complexity region
|
159 |
174 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000132459
|
| SMART Domains |
Protein: ENSMUSP00000116429
Gene: ENSMUSG00000039262
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:BAT2_N
|
1 |
119 |
9.8e-24 |
PFAM |
|
low complexity region
|
287 |
302 |
N/A |
INTRINSIC |
|
low complexity region
|
316 |
322 |
N/A |
INTRINSIC |
|
low complexity region
|
341 |
352 |
N/A |
INTRINSIC |
|
coiled coil region
|
421 |
471 |
N/A |
INTRINSIC |
|
low complexity region
|
528 |
549 |
N/A |
INTRINSIC |
|
low complexity region
|
566 |
584 |
N/A |
INTRINSIC |
|
low complexity region
|
813 |
828 |
N/A |
INTRINSIC |
|
low complexity region
|
920 |
935 |
N/A |
INTRINSIC |
|
low complexity region
|
1040 |
1054 |
N/A |
INTRINSIC |
|
low complexity region
|
1146 |
1161 |
N/A |
INTRINSIC |
|
low complexity region
|
1185 |
1203 |
N/A |
INTRINSIC |
|
low complexity region
|
1330 |
1349 |
N/A |
INTRINSIC |
|
low complexity region
|
1353 |
1365 |
N/A |
INTRINSIC |
|
low complexity region
|
1403 |
1416 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000156313
|
| SMART Domains |
Protein: ENSMUSP00000114994
Gene: ENSMUSG00000039262
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
125 |
140 |
N/A |
INTRINSIC |
|
low complexity region
|
231 |
246 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.6%
- 20x: 98.8%
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 91 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Acaca |
G |
A |
11: 84,154,138 (GRCm39) |
R953Q |
possibly damaging |
Het |
| Aldh1a1 |
A |
T |
19: 20,579,434 (GRCm39) |
H20L |
probably benign |
Het |
| Ankrd52 |
T |
A |
10: 128,219,526 (GRCm39) |
C487S |
probably benign |
Het |
| Ap1s3 |
T |
C |
1: 79,602,845 (GRCm39) |
E54G |
probably benign |
Het |
| Arglu1 |
A |
C |
8: 8,717,361 (GRCm39) |
M236R |
probably benign |
Het |
| Baz1b |
T |
A |
5: 135,246,293 (GRCm39) |
F581I |
probably benign |
Het |
| Bbox1 |
T |
G |
2: 110,122,884 (GRCm39) |
D135A |
probably benign |
Het |
| Bcl2l14 |
T |
A |
6: 134,400,786 (GRCm39) |
V69E |
probably damaging |
Het |
| Brinp3 |
C |
T |
1: 146,390,627 (GRCm39) |
Q58* |
probably null |
Het |
| Ccnb1ip1 |
T |
A |
14: 51,029,724 (GRCm39) |
K113* |
probably null |
Het |
| Cep128 |
T |
C |
12: 91,200,878 (GRCm39) |
I830M |
probably damaging |
Het |
| Ces2f |
C |
T |
8: 105,681,284 (GRCm39) |
T541I |
probably damaging |
Het |
| Chsy3 |
C |
A |
18: 59,309,149 (GRCm39) |
P134Q |
possibly damaging |
Het |
| Cobl |
T |
G |
11: 12,328,271 (GRCm39) |
T112P |
probably damaging |
Het |
| Cplane2 |
A |
T |
4: 140,947,159 (GRCm39) |
Y180F |
probably benign |
Het |
| Dcc |
T |
A |
18: 71,680,469 (GRCm39) |
K589I |
probably benign |
Het |
| Depdc1b |
T |
A |
13: 108,523,505 (GRCm39) |
I460K |
possibly damaging |
Het |
| Dlst |
T |
C |
12: 85,157,705 (GRCm39) |
F12S |
probably benign |
Het |
| Dnah1 |
G |
C |
14: 31,019,067 (GRCm39) |
F1342L |
probably damaging |
Het |
| Dtnb |
A |
G |
12: 3,798,480 (GRCm39) |
Q438R |
possibly damaging |
Het |
| Dusp4 |
C |
A |
8: 35,275,065 (GRCm39) |
S61R |
probably damaging |
Het |
| E130308A19Rik |
A |
G |
4: 59,737,688 (GRCm39) |
Y433C |
probably damaging |
Het |
| Ebf2 |
T |
C |
14: 67,661,407 (GRCm39) |
S512P |
probably benign |
Het |
| Elapor2 |
A |
G |
5: 9,460,709 (GRCm39) |
N210S |
probably benign |
Het |
| Eya1 |
C |
T |
1: 14,301,636 (GRCm39) |
|
probably null |
Het |
| Fsd1 |
G |
A |
17: 56,300,876 (GRCm39) |
R245H |
probably damaging |
Het |
| Fzr1 |
T |
A |
10: 81,204,463 (GRCm39) |
D379V |
probably damaging |
Het |
| Gk2 |
T |
A |
5: 97,604,195 (GRCm39) |
E214D |
probably benign |
Het |
| Gm10837 |
C |
G |
14: 122,728,142 (GRCm39) |
A6G |
unknown |
Het |
| Gmnc |
A |
T |
16: 26,779,272 (GRCm39) |
V251E |
probably benign |
Het |
| Golga3 |
A |
G |
5: 110,340,953 (GRCm39) |
Q549R |
probably damaging |
Het |
| Gsdmd |
T |
G |
15: 75,736,204 (GRCm39) |
V111G |
probably damaging |
Het |
| Gtf3c1 |
T |
C |
7: 125,244,914 (GRCm39) |
T1707A |
possibly damaging |
Het |
| Gucy2c |
C |
T |
6: 136,674,937 (GRCm39) |
V1049M |
probably benign |
Het |
| Gucy2g |
A |
G |
19: 55,229,583 (GRCm39) |
V29A |
probably damaging |
Het |
| Hecw1 |
A |
T |
13: 14,609,044 (GRCm39) |
M1K |
probably null |
Het |
| Hmcn1 |
T |
C |
1: 150,736,118 (GRCm39) |
D117G |
probably damaging |
Het |
| Ifnab |
T |
A |
4: 88,609,350 (GRCm39) |
T39S |
possibly damaging |
Het |
| Lcorl |
A |
G |
5: 45,904,566 (GRCm39) |
Y171H |
probably damaging |
Het |
| Ly6g6c |
C |
T |
17: 35,288,437 (GRCm39) |
P103L |
probably damaging |
Het |
| Macf1 |
T |
G |
4: 123,325,936 (GRCm39) |
E5189A |
probably damaging |
Het |
| Mapkap1 |
A |
G |
2: 34,453,151 (GRCm39) |
E348G |
probably damaging |
Het |
| Med25 |
G |
T |
7: 44,534,325 (GRCm39) |
A280D |
probably damaging |
Het |
| Mep1b |
C |
A |
18: 21,233,108 (GRCm39) |
A703E |
probably benign |
Het |
| Morn5 |
T |
A |
2: 35,944,990 (GRCm39) |
N71K |
probably benign |
Het |
| Mtmr10 |
T |
A |
7: 63,970,375 (GRCm39) |
Y373N |
possibly damaging |
Het |
| Myo1d |
C |
T |
11: 80,565,460 (GRCm39) |
E426K |
probably damaging |
Het |
| Ncbp1 |
G |
C |
4: 46,155,756 (GRCm39) |
V302L |
probably benign |
Het |
| Notch4 |
A |
G |
17: 34,801,520 (GRCm39) |
T1123A |
possibly damaging |
Het |
| Nudt18 |
T |
A |
14: 70,816,452 (GRCm39) |
M88K |
possibly damaging |
Het |
| Or12k8 |
A |
G |
2: 36,975,608 (GRCm39) |
S51P |
possibly damaging |
Het |
| Or5b100-ps1 |
A |
T |
19: 12,994,097 (GRCm39) |
D170V |
possibly damaging |
Het |
| Or6d12 |
T |
A |
6: 116,493,632 (GRCm39) |
L298Q |
probably damaging |
Het |
| Or8g4 |
A |
T |
9: 39,661,787 (GRCm39) |
Y35F |
possibly damaging |
Het |
| Pdcd6ip |
T |
C |
9: 113,488,953 (GRCm39) |
N694S |
probably benign |
Het |
| Pecam1 |
T |
A |
11: 106,579,773 (GRCm39) |
T430S |
probably benign |
Het |
| Plaa |
T |
G |
4: 94,462,288 (GRCm39) |
T530P |
probably benign |
Het |
| Ppfia3 |
G |
T |
7: 45,010,019 (GRCm39) |
Q95K |
probably damaging |
Het |
| Ppp4r2 |
T |
C |
6: 100,843,274 (GRCm39) |
S331P |
probably benign |
Het |
| Prg4 |
T |
C |
1: 150,334,014 (GRCm39) |
T117A |
possibly damaging |
Het |
| Ptk2 |
G |
A |
15: 73,093,658 (GRCm39) |
P854S |
possibly damaging |
Het |
| Rasef |
T |
C |
4: 73,698,626 (GRCm39) |
I12V |
probably benign |
Het |
| Robo2 |
T |
G |
16: 74,149,504 (GRCm39) |
Y108S |
probably damaging |
Het |
| Rp1 |
T |
A |
1: 4,277,014 (GRCm39) |
E762V |
unknown |
Het |
| Rsrc1 |
T |
C |
3: 66,901,987 (GRCm39) |
S46P |
unknown |
Het |
| Rttn |
A |
T |
18: 89,027,546 (GRCm39) |
T554S |
probably benign |
Het |
| Sall3 |
C |
T |
18: 81,017,314 (GRCm39) |
V205M |
probably damaging |
Het |
| Scn3a |
C |
A |
2: 65,327,944 (GRCm39) |
V849L |
probably damaging |
Het |
| Sec23a |
A |
G |
12: 59,039,069 (GRCm39) |
C277R |
probably benign |
Het |
| Sf3b3 |
C |
T |
8: 111,539,639 (GRCm39) |
A1075T |
possibly damaging |
Het |
| Sfxn5 |
T |
C |
6: 85,309,366 (GRCm39) |
D113G |
unknown |
Het |
| Slc22a22 |
C |
T |
15: 57,126,876 (GRCm39) |
M64I |
probably benign |
Het |
| Slc5a11 |
C |
T |
7: 122,857,669 (GRCm39) |
P253S |
probably damaging |
Het |
| Smarcd3 |
A |
G |
5: 24,798,067 (GRCm39) |
F449S |
probably damaging |
Het |
| Sspo |
C |
T |
6: 48,437,313 (GRCm39) |
T1357M |
probably damaging |
Het |
| Styx |
C |
T |
14: 45,609,873 (GRCm39) |
T179I |
probably benign |
Het |
| Syt7 |
A |
T |
19: 10,412,963 (GRCm39) |
T297S |
probably benign |
Het |
| Tbx19 |
T |
A |
1: 164,988,135 (GRCm39) |
|
probably benign |
Het |
| Tg |
T |
A |
15: 66,545,392 (GRCm39) |
V149E |
probably damaging |
Het |
| Tgfbr3l |
T |
A |
8: 4,299,238 (GRCm39) |
L35Q |
probably damaging |
Het |
| Tmem161b |
C |
A |
13: 84,370,537 (GRCm39) |
|
probably benign |
Het |
| Tmem219 |
T |
A |
7: 126,490,975 (GRCm39) |
T161S |
probably damaging |
Het |
| Tox2 |
T |
A |
2: 163,162,501 (GRCm39) |
L68H |
|
Het |
| Trim5 |
T |
A |
7: 103,927,681 (GRCm39) |
D153V |
possibly damaging |
Het |
| Ttn |
T |
C |
2: 76,580,651 (GRCm39) |
Y23414C |
probably damaging |
Het |
| Ttn |
A |
T |
2: 76,582,153 (GRCm39) |
N22913K |
probably damaging |
Het |
| Ubr2 |
A |
C |
17: 47,266,779 (GRCm39) |
M1124R |
possibly damaging |
Het |
| Vmn2r75 |
A |
G |
7: 85,815,568 (GRCm39) |
S99P |
probably damaging |
Het |
| Wdr83 |
T |
C |
8: 85,802,680 (GRCm39) |
D219G |
probably damaging |
Het |
| Wdr90 |
C |
T |
17: 26,068,623 (GRCm39) |
V1285M |
probably damaging |
Het |
| Zmynd15 |
A |
T |
11: 70,351,581 (GRCm39) |
L62F |
probably damaging |
Het |
|
| Other mutations in Prrc2b |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00156:Prrc2b
|
APN |
2 |
32,098,731 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00846:Prrc2b
|
APN |
2 |
32,089,109 (GRCm39) |
splice site |
probably benign |
|
|
IGL00977:Prrc2b
|
APN |
2 |
32,103,822 (GRCm39) |
missense |
probably benign |
0.05 |
|
IGL01372:Prrc2b
|
APN |
2 |
32,113,942 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01993:Prrc2b
|
APN |
2 |
32,114,057 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
IGL02097:Prrc2b
|
APN |
2 |
32,081,513 (GRCm39) |
splice site |
probably benign |
|
|
IGL02165:Prrc2b
|
APN |
2 |
32,104,652 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02184:Prrc2b
|
APN |
2 |
32,111,467 (GRCm39) |
missense |
probably benign |
0.19 |
|
IGL02238:Prrc2b
|
APN |
2 |
32,103,429 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02338:Prrc2b
|
APN |
2 |
32,104,047 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL02399:Prrc2b
|
APN |
2 |
32,116,973 (GRCm39) |
nonsense |
probably null |
|
|
IGL02597:Prrc2b
|
APN |
2 |
32,109,625 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02729:Prrc2b
|
APN |
2 |
32,098,770 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02743:Prrc2b
|
APN |
2 |
32,084,441 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02815:Prrc2b
|
APN |
2 |
32,094,265 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03159:Prrc2b
|
APN |
2 |
32,084,498 (GRCm39) |
missense |
probably damaging |
0.98 |
|
BB002:Prrc2b
|
UTSW |
2 |
32,094,127 (GRCm39) |
missense |
probably damaging |
1.00 |
|
BB012:Prrc2b
|
UTSW |
2 |
32,094,127 (GRCm39) |
missense |
probably damaging |
1.00 |
|
FR4304:Prrc2b
|
UTSW |
2 |
32,111,179 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0082:Prrc2b
|
UTSW |
2 |
32,102,310 (GRCm39) |
splice site |
probably benign |
|
|
R0105:Prrc2b
|
UTSW |
2 |
32,103,323 (GRCm39) |
nonsense |
probably null |
|
|
R0276:Prrc2b
|
UTSW |
2 |
32,109,666 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R0325:Prrc2b
|
UTSW |
2 |
32,089,103 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0436:Prrc2b
|
UTSW |
2 |
32,120,672 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0595:Prrc2b
|
UTSW |
2 |
32,073,189 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0607:Prrc2b
|
UTSW |
2 |
32,103,882 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0650:Prrc2b
|
UTSW |
2 |
32,119,267 (GRCm39) |
splice site |
probably benign |
|
|
R1282:Prrc2b
|
UTSW |
2 |
32,113,456 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R1421:Prrc2b
|
UTSW |
2 |
32,090,990 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R1452:Prrc2b
|
UTSW |
2 |
32,084,997 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1535:Prrc2b
|
UTSW |
2 |
32,094,301 (GRCm39) |
missense |
probably benign |
0.06 |
|
R1709:Prrc2b
|
UTSW |
2 |
32,084,473 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1710:Prrc2b
|
UTSW |
2 |
32,102,234 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2094:Prrc2b
|
UTSW |
2 |
32,072,582 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2202:Prrc2b
|
UTSW |
2 |
32,113,476 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2203:Prrc2b
|
UTSW |
2 |
32,113,476 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2204:Prrc2b
|
UTSW |
2 |
32,113,476 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2428:Prrc2b
|
UTSW |
2 |
32,106,067 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2435:Prrc2b
|
UTSW |
2 |
32,109,741 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3439:Prrc2b
|
UTSW |
2 |
32,096,359 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4175:Prrc2b
|
UTSW |
2 |
32,108,820 (GRCm39) |
intron |
probably benign |
|
|
R4710:Prrc2b
|
UTSW |
2 |
32,083,869 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R4728:Prrc2b
|
UTSW |
2 |
32,120,637 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4791:Prrc2b
|
UTSW |
2 |
32,107,351 (GRCm39) |
splice site |
probably null |
|
|
R4876:Prrc2b
|
UTSW |
2 |
32,104,212 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4908:Prrc2b
|
UTSW |
2 |
32,116,330 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R4997:Prrc2b
|
UTSW |
2 |
32,112,323 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5240:Prrc2b
|
UTSW |
2 |
32,096,408 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5276:Prrc2b
|
UTSW |
2 |
32,104,734 (GRCm39) |
missense |
probably benign |
0.09 |
|
R5455:Prrc2b
|
UTSW |
2 |
32,111,355 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R5821:Prrc2b
|
UTSW |
2 |
32,102,144 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5835:Prrc2b
|
UTSW |
2 |
32,096,485 (GRCm39) |
missense |
probably benign |
0.18 |
|
R5958:Prrc2b
|
UTSW |
2 |
32,102,092 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R6052:Prrc2b
|
UTSW |
2 |
32,102,297 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R6218:Prrc2b
|
UTSW |
2 |
32,098,823 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6428:Prrc2b
|
UTSW |
2 |
32,116,508 (GRCm39) |
splice site |
probably null |
|
|
R6505:Prrc2b
|
UTSW |
2 |
32,112,332 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6812:Prrc2b
|
UTSW |
2 |
32,103,153 (GRCm39) |
missense |
probably benign |
0.30 |
|
R6826:Prrc2b
|
UTSW |
2 |
32,112,300 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R6827:Prrc2b
|
UTSW |
2 |
32,090,963 (GRCm39) |
missense |
probably benign |
0.37 |
|
R7021:Prrc2b
|
UTSW |
2 |
32,111,498 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7081:Prrc2b
|
UTSW |
2 |
32,103,075 (GRCm39) |
missense |
probably benign |
0.12 |
|
R7101:Prrc2b
|
UTSW |
2 |
32,117,005 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R7215:Prrc2b
|
UTSW |
2 |
32,119,309 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7228:Prrc2b
|
UTSW |
2 |
32,104,318 (GRCm39) |
nonsense |
probably null |
|
|
R7566:Prrc2b
|
UTSW |
2 |
32,084,402 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7719:Prrc2b
|
UTSW |
2 |
32,107,280 (GRCm39) |
nonsense |
probably null |
|
|
R7925:Prrc2b
|
UTSW |
2 |
32,094,127 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7999:Prrc2b
|
UTSW |
2 |
32,084,426 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R8099:Prrc2b
|
UTSW |
2 |
32,098,686 (GRCm39) |
missense |
probably benign |
0.06 |
|
R8154:Prrc2b
|
UTSW |
2 |
32,108,689 (GRCm39) |
missense |
probably benign |
0.42 |
|
R8252:Prrc2b
|
UTSW |
2 |
32,109,392 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R8379:Prrc2b
|
UTSW |
2 |
32,104,666 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R8485:Prrc2b
|
UTSW |
2 |
32,102,105 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R8845:Prrc2b
|
UTSW |
2 |
32,106,162 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R8845:Prrc2b
|
UTSW |
2 |
32,102,105 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R8919:Prrc2b
|
UTSW |
2 |
32,104,953 (GRCm39) |
missense |
probably benign |
|
|
R8982:Prrc2b
|
UTSW |
2 |
32,102,134 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9065:Prrc2b
|
UTSW |
2 |
32,109,304 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9127:Prrc2b
|
UTSW |
2 |
32,103,764 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9217:Prrc2b
|
UTSW |
2 |
32,103,414 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9338:Prrc2b
|
UTSW |
2 |
32,098,779 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9344:Prrc2b
|
UTSW |
2 |
32,103,600 (GRCm39) |
missense |
probably benign |
0.28 |
|
R9386:Prrc2b
|
UTSW |
2 |
32,104,125 (GRCm39) |
missense |
probably benign |
|
|
R9601:Prrc2b
|
UTSW |
2 |
32,090,953 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9607:Prrc2b
|
UTSW |
2 |
32,098,794 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9670:Prrc2b
|
UTSW |
2 |
32,103,199 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9706:Prrc2b
|
UTSW |
2 |
32,107,300 (GRCm39) |
missense |
probably benign |
0.00 |
|
Z1088:Prrc2b
|
UTSW |
2 |
32,106,744 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1088:Prrc2b
|
UTSW |
2 |
32,104,441 (GRCm39) |
missense |
probably benign |
0.03 |
|
Z1177:Prrc2b
|
UTSW |
2 |
32,116,364 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- TCCTCTTGGGAGAAGGAAGG -3'
(R):5'- GGCCTGTTCCTCATCAATGAAG -3'
Sequencing Primer
(F):5'- AGCCTGAGTGGACACCTGAG -3'
(R):5'- CTGTTCCTCATCAATGAAGATCCAG -3'
|
| Posted On |
2019-05-15 |
Incidental Mutation