Incidental Mutation 'R7097:Chl1'
| ID |
550554 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Chl1
|
| Ensembl Gene |
ENSMUSG00000030077 |
| Gene Name |
cell adhesion molecule L1-like |
| Synonyms |
A530023M13Rik, close homolog of L1, LICAM2, CALL |
| MMRRC Submission |
045189-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly non essential
(E-score: 0.458)
|
| Stock # |
R7097 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
6 |
| Chromosomal Location |
103487372-103709999 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 103683409 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Leucine to Proline
at position 745
(L745P)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000063933
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000066905]
[ENSMUST00000203830]
[ENSMUST00000203912]
[ENSMUST00000205098]
|
| AlphaFold |
P70232 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000066905
AA Change: L745P
PolyPhen 2
Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000063933
Gene: ENSMUSG00000030077
AA Change: L745P
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
25 |
N/A |
INTRINSIC |
|
IG_like
|
48 |
116 |
3.14e-2 |
SMART |
|
IG
|
138 |
225 |
1.36e-5 |
SMART |
|
IGc2
|
253 |
317 |
3.76e-17 |
SMART |
|
IGc2
|
343 |
408 |
1.61e-7 |
SMART |
|
IGc2
|
436 |
501 |
1.56e-5 |
SMART |
|
IG
|
521 |
609 |
6.02e-7 |
SMART |
|
IG_like
|
539 |
598 |
1.27e-1 |
SMART |
|
FN3
|
612 |
695 |
2.24e-13 |
SMART |
|
FN3
|
712 |
794 |
1.92e-3 |
SMART |
|
FN3
|
810 |
901 |
2.3e-1 |
SMART |
|
FN3
|
916 |
1002 |
4.09e-7 |
SMART |
|
transmembrane domain
|
1082 |
1104 |
N/A |
INTRINSIC |
|
Pfam:Bravo_FIGEY
|
1105 |
1190 |
3.9e-33 |
PFAM |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000203830
AA Change: L745P
PolyPhen 2
Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000144758
Gene: ENSMUSG00000030077
AA Change: L745P
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
25 |
N/A |
INTRINSIC |
|
IG_like
|
48 |
116 |
3.14e-2 |
SMART |
|
IG
|
138 |
225 |
1.36e-5 |
SMART |
|
IGc2
|
253 |
317 |
3.76e-17 |
SMART |
|
IGc2
|
343 |
408 |
1.61e-7 |
SMART |
|
IGc2
|
436 |
501 |
1.56e-5 |
SMART |
|
IG
|
521 |
609 |
6.02e-7 |
SMART |
|
IG_like
|
539 |
598 |
1.27e-1 |
SMART |
|
FN3
|
612 |
695 |
2.24e-13 |
SMART |
|
FN3
|
712 |
794 |
1.92e-3 |
SMART |
|
FN3
|
810 |
901 |
2.3e-1 |
SMART |
|
FN3
|
916 |
1002 |
4.09e-7 |
SMART |
|
transmembrane domain
|
1082 |
1104 |
N/A |
INTRINSIC |
|
Pfam:Bravo_FIGEY
|
1105 |
1190 |
3.9e-33 |
PFAM |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000203912
AA Change: L761P
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000145026
Gene: ENSMUSG00000030077
AA Change: L761P
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
25 |
N/A |
INTRINSIC |
|
IG_like
|
48 |
116 |
3.14e-2 |
SMART |
|
IG
|
138 |
225 |
1.36e-5 |
SMART |
|
IGc2
|
269 |
333 |
3.76e-17 |
SMART |
|
IGc2
|
359 |
424 |
1.61e-7 |
SMART |
|
IGc2
|
452 |
517 |
1.56e-5 |
SMART |
|
IG
|
537 |
625 |
6.02e-7 |
SMART |
|
IG_like
|
555 |
614 |
1.27e-1 |
SMART |
|
FN3
|
628 |
711 |
2.24e-13 |
SMART |
|
FN3
|
728 |
810 |
1.92e-3 |
SMART |
|
FN3
|
826 |
917 |
2.3e-1 |
SMART |
|
FN3
|
932 |
1018 |
4.09e-7 |
SMART |
|
transmembrane domain
|
1044 |
1066 |
N/A |
INTRINSIC |
|
Pfam:Bravo_FIGEY
|
1067 |
1131 |
2.5e-12 |
PFAM |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000205098
AA Change: L18P
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000144739
Gene: ENSMUSG00000030077
AA Change: L18P
| Domain | Start | End | E-Value | Type |
|---|
|
FN3
|
4 |
67 |
4.4e-1 |
SMART |
|
FN3
|
83 |
174 |
1.2e-3 |
SMART |
|
FN3
|
189 |
275 |
2.1e-9 |
SMART |
|
transmembrane domain
|
301 |
323 |
N/A |
INTRINSIC |
|
Pfam:Bravo_FIGEY
|
324 |
409 |
3.6e-30 |
PFAM |
|
| Meta Mutation Damage Score |
0.6998 |
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 100.0%
- 10x: 99.7%
- 20x: 99.1%
|
| Validation Efficiency |
99% (75/76) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene is a member of the L1 gene family of neural cell adhesion molecules. It is a neural recognition molecule that may be involved in signal transduction pathways. The deletion of one copy of this gene may be responsible for mental defects in patients with 3p- syndrome. This protein may also play a role in the growth of certain cancers. Alternate splicing results in both coding and non-coding variants. [provided by RefSeq, Nov 2011]
PHENOTYPE: Homozygous mutation of this gene results in enlargement of the lateral ventricles and altered hippocampal mossy fiber organization. Mutant animals exhibit altered exploratory behavior. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 75 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1700010I14Rik |
A |
G |
17: 9,224,052 (GRCm39) |
N435S |
probably damaging |
Het |
| Aip |
A |
T |
19: 4,165,381 (GRCm39) |
V195E |
probably benign |
Het |
| Amer3 |
A |
T |
1: 34,627,869 (GRCm39) |
I703F |
probably benign |
Het |
| Amfr |
T |
C |
8: 94,738,637 (GRCm39) |
E7G |
probably benign |
Het |
| Angel1 |
A |
G |
12: 86,773,158 (GRCm39) |
S4P |
probably damaging |
Het |
| Atp2c1 |
A |
G |
9: 105,341,850 (GRCm39) |
I146T |
probably damaging |
Het |
| Atp6v0e |
A |
G |
17: 26,914,390 (GRCm39) |
T72A |
probably benign |
Het |
| Bahcc1 |
T |
C |
11: 120,163,472 (GRCm39) |
V590A |
possibly damaging |
Het |
| Bcl6 |
A |
G |
16: 23,791,364 (GRCm39) |
V330A |
possibly damaging |
Het |
| Bcl6 |
T |
C |
16: 23,791,652 (GRCm39) |
D234G |
probably damaging |
Het |
| Btaf1 |
C |
T |
19: 36,926,502 (GRCm39) |
T58I |
probably damaging |
Het |
| Ccdc175 |
A |
T |
12: 72,175,183 (GRCm39) |
|
probably null |
Het |
| Cdca4 |
C |
A |
12: 112,785,189 (GRCm39) |
V180L |
probably benign |
Het |
| Ces1g |
C |
A |
8: 94,043,665 (GRCm39) |
G425C |
possibly damaging |
Het |
| Clec4g |
T |
A |
8: 3,769,518 (GRCm39) |
T42S |
possibly damaging |
Het |
| Ctsg |
A |
C |
14: 56,337,489 (GRCm39) |
I238S |
probably damaging |
Het |
| Cyb5rl |
A |
T |
4: 106,944,513 (GRCm39) |
E41V |
unknown |
Het |
| Dcdc2a |
A |
G |
13: 25,291,681 (GRCm39) |
E222G |
probably benign |
Het |
| Dnaaf1 |
G |
T |
8: 120,323,538 (GRCm39) |
G509V |
possibly damaging |
Het |
| Dnah5 |
A |
G |
15: 28,453,410 (GRCm39) |
I4394V |
probably benign |
Het |
| Dot1l |
T |
G |
10: 80,626,560 (GRCm39) |
S1260R |
probably damaging |
Het |
| Dst |
T |
G |
1: 34,208,341 (GRCm39) |
I1089S |
probably damaging |
Het |
| Efcab3 |
A |
T |
11: 104,899,787 (GRCm39) |
I4350F |
possibly damaging |
Het |
| Eps8l3 |
A |
G |
3: 107,791,801 (GRCm39) |
|
probably null |
Het |
| Fam135b |
A |
G |
15: 71,493,917 (GRCm39) |
V4A |
possibly damaging |
Het |
| Fnip2 |
T |
C |
3: 79,388,313 (GRCm39) |
E806G |
probably benign |
Het |
| Fryl |
T |
A |
5: 73,231,251 (GRCm39) |
I1609F |
probably benign |
Het |
| Gdi1 |
G |
A |
X: 73,350,461 (GRCm39) |
R55H |
probably benign |
Het |
| Gsn |
A |
T |
2: 35,185,061 (GRCm39) |
K339* |
probably null |
Het |
| Hecw2 |
T |
A |
1: 53,904,283 (GRCm39) |
Y1155F |
possibly damaging |
Het |
| Kif20b |
T |
A |
19: 34,951,892 (GRCm39) |
N1723K |
probably damaging |
Het |
| Kif2b |
T |
C |
11: 91,467,650 (GRCm39) |
D211G |
probably benign |
Het |
| Lhfpl4 |
C |
T |
6: 113,153,632 (GRCm39) |
V140I |
probably benign |
Het |
| Med16 |
C |
T |
10: 79,739,177 (GRCm39) |
G203D |
probably damaging |
Het |
| Mrgpra3 |
T |
A |
7: 47,239,389 (GRCm39) |
Y179F |
probably benign |
Het |
| Muc6 |
AGGCGCAGAAACCCTGGC |
AGGC |
7: 141,214,363 (GRCm39) |
|
probably null |
Het |
| Myo18b |
A |
G |
5: 113,022,271 (GRCm39) |
S374P |
unknown |
Het |
| Myoz1 |
A |
G |
14: 20,699,477 (GRCm39) |
I287T |
possibly damaging |
Het |
| Ncoa6 |
T |
C |
2: 155,279,983 (GRCm39) |
D11G |
probably benign |
Het |
| Nlrp9c |
A |
G |
7: 26,085,046 (GRCm39) |
Y178H |
probably damaging |
Het |
| Nmur1 |
T |
C |
1: 86,315,230 (GRCm39) |
T212A |
probably damaging |
Het |
| Oacyl |
A |
G |
18: 65,853,323 (GRCm39) |
D143G |
probably benign |
Het |
| Obox5 |
A |
G |
7: 15,492,732 (GRCm39) |
Y229C |
probably damaging |
Het |
| Or10d1c |
A |
T |
9: 38,893,914 (GRCm39) |
M142K |
probably benign |
Het |
| Or1j12 |
A |
G |
2: 36,342,702 (GRCm39) |
Y35C |
probably damaging |
Het |
| Or1j18 |
G |
T |
2: 36,624,436 (GRCm39) |
M34I |
probably benign |
Het |
| Or1x2 |
C |
A |
11: 50,918,428 (GRCm39) |
L200I |
probably benign |
Het |
| Or8c13 |
A |
T |
9: 38,091,632 (GRCm39) |
C162* |
probably null |
Het |
| Pcdhb17 |
A |
C |
18: 37,619,566 (GRCm39) |
N452T |
probably benign |
Het |
| Pear1 |
T |
G |
3: 87,658,752 (GRCm39) |
H901P |
probably benign |
Het |
| Peds1 |
C |
G |
2: 167,503,398 (GRCm39) |
A7P |
probably benign |
Het |
| Pi16 |
A |
G |
17: 29,545,313 (GRCm39) |
Y192C |
probably damaging |
Het |
| Pip5k1b |
T |
G |
19: 24,335,424 (GRCm39) |
E362D |
probably damaging |
Het |
| Pla2g5 |
T |
C |
4: 138,531,830 (GRCm39) |
D58G |
probably damaging |
Het |
| Pole |
T |
A |
5: 110,472,968 (GRCm39) |
|
probably null |
Het |
| Prdm16 |
G |
T |
4: 154,429,925 (GRCm39) |
T348K |
probably damaging |
Het |
| Prkdc |
T |
A |
16: 15,507,207 (GRCm39) |
F896I |
probably damaging |
Het |
| Prmt7 |
T |
C |
8: 106,961,732 (GRCm39) |
F215S |
unknown |
Het |
| Prss23 |
T |
A |
7: 89,159,392 (GRCm39) |
T226S |
probably damaging |
Het |
| Ptpn14 |
G |
A |
1: 189,595,595 (GRCm39) |
W739* |
probably null |
Het |
| Rfx5 |
G |
T |
3: 94,863,850 (GRCm39) |
G135C |
probably damaging |
Het |
| Scmh1 |
A |
G |
4: 120,382,252 (GRCm39) |
H573R |
probably benign |
Het |
| Serpina5 |
G |
T |
12: 104,068,554 (GRCm39) |
|
probably null |
Het |
| Sh3rf2 |
G |
A |
18: 42,237,227 (GRCm39) |
|
probably null |
Het |
| Slc38a2 |
T |
C |
15: 96,591,182 (GRCm39) |
M229V |
probably damaging |
Het |
| Slc6a17 |
C |
G |
3: 107,400,464 (GRCm39) |
G222R |
probably damaging |
Het |
| Sp110 |
C |
T |
1: 85,507,406 (GRCm39) |
G367D |
possibly damaging |
Het |
| Srcap |
C |
A |
7: 127,138,213 (GRCm39) |
L1128M |
probably damaging |
Het |
| Tpra1 |
T |
A |
6: 88,885,276 (GRCm39) |
I76N |
probably damaging |
Het |
| Trav6-4 |
A |
T |
14: 53,692,049 (GRCm39) |
Y52F |
probably benign |
Het |
| Trp63 |
C |
A |
16: 25,639,227 (GRCm39) |
H138Q |
probably damaging |
Het |
| Trub2 |
A |
G |
2: 29,669,838 (GRCm39) |
V177A |
possibly damaging |
Het |
| Ugt2a2 |
T |
C |
5: 87,608,255 (GRCm39) |
D528G |
possibly damaging |
Het |
| Wnk2 |
C |
A |
13: 49,256,314 (GRCm39) |
R269L |
possibly damaging |
Het |
| Zc3h12c |
T |
A |
9: 52,027,226 (GRCm39) |
Q731L |
possibly damaging |
Het |
|
| Other mutations in Chl1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00590:Chl1
|
APN |
6 |
103,670,022 (GRCm39) |
missense |
probably benign |
0.08 |
|
IGL00786:Chl1
|
APN |
6 |
103,652,106 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00959:Chl1
|
APN |
6 |
103,686,211 (GRCm39) |
splice site |
probably null |
|
|
IGL01109:Chl1
|
APN |
6 |
103,692,354 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01354:Chl1
|
APN |
6 |
103,642,814 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL01367:Chl1
|
APN |
6 |
103,706,186 (GRCm39) |
missense |
probably benign |
0.42 |
|
IGL01371:Chl1
|
APN |
6 |
103,692,325 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01599:Chl1
|
APN |
6 |
103,685,445 (GRCm39) |
missense |
probably benign |
0.34 |
|
IGL01724:Chl1
|
APN |
6 |
103,626,534 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02001:Chl1
|
APN |
6 |
103,619,017 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
IGL02066:Chl1
|
APN |
6 |
103,675,185 (GRCm39) |
missense |
probably benign |
0.39 |
|
IGL02122:Chl1
|
APN |
6 |
103,652,098 (GRCm39) |
missense |
probably benign |
0.39 |
|
IGL02340:Chl1
|
APN |
6 |
103,675,086 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02420:Chl1
|
APN |
6 |
103,692,330 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02421:Chl1
|
APN |
6 |
103,694,541 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02429:Chl1
|
APN |
6 |
103,641,770 (GRCm39) |
unclassified |
probably benign |
|
|
IGL02825:Chl1
|
APN |
6 |
103,645,764 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
IGL02858:Chl1
|
APN |
6 |
103,618,949 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03169:Chl1
|
APN |
6 |
103,642,928 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03185:Chl1
|
APN |
6 |
103,642,824 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03189:Chl1
|
APN |
6 |
103,660,168 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
IGL03288:Chl1
|
APN |
6 |
103,652,058 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03404:Chl1
|
APN |
6 |
103,670,052 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03052:Chl1
|
UTSW |
6 |
103,668,628 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0060:Chl1
|
UTSW |
6 |
103,688,019 (GRCm39) |
splice site |
probably benign |
|
|
R0060:Chl1
|
UTSW |
6 |
103,688,019 (GRCm39) |
splice site |
probably benign |
|
|
R0062:Chl1
|
UTSW |
6 |
103,726,613 (GRCm39) |
missense |
unknown |
|
|
R0314:Chl1
|
UTSW |
6 |
103,624,262 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0322:Chl1
|
UTSW |
6 |
103,678,844 (GRCm39) |
splice site |
probably benign |
|
|
R0685:Chl1
|
UTSW |
6 |
103,685,503 (GRCm39) |
splice site |
probably null |
|
|
R0702:Chl1
|
UTSW |
6 |
103,683,583 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1056:Chl1
|
UTSW |
6 |
103,652,038 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R1138:Chl1
|
UTSW |
6 |
103,670,140 (GRCm39) |
missense |
probably benign |
0.05 |
|
R1483:Chl1
|
UTSW |
6 |
103,624,248 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1571:Chl1
|
UTSW |
6 |
103,685,445 (GRCm39) |
missense |
probably benign |
0.34 |
|
R1620:Chl1
|
UTSW |
6 |
103,667,203 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1645:Chl1
|
UTSW |
6 |
103,660,141 (GRCm39) |
missense |
probably benign |
0.06 |
|
R1773:Chl1
|
UTSW |
6 |
103,624,292 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1852:Chl1
|
UTSW |
6 |
103,676,120 (GRCm39) |
splice site |
probably null |
|
|
R1891:Chl1
|
UTSW |
6 |
103,691,544 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R2146:Chl1
|
UTSW |
6 |
103,692,362 (GRCm39) |
critical splice donor site |
probably null |
|
|
R2147:Chl1
|
UTSW |
6 |
103,692,362 (GRCm39) |
critical splice donor site |
probably null |
|
|
R2148:Chl1
|
UTSW |
6 |
103,692,362 (GRCm39) |
critical splice donor site |
probably null |
|
|
R2163:Chl1
|
UTSW |
6 |
103,688,192 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2291:Chl1
|
UTSW |
6 |
103,692,354 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2920:Chl1
|
UTSW |
6 |
103,672,304 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3611:Chl1
|
UTSW |
6 |
103,675,116 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3979:Chl1
|
UTSW |
6 |
103,692,245 (GRCm39) |
nonsense |
probably null |
|
|
R4987:Chl1
|
UTSW |
6 |
103,651,938 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5266:Chl1
|
UTSW |
6 |
103,677,504 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5478:Chl1
|
UTSW |
6 |
103,660,182 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5523:Chl1
|
UTSW |
6 |
103,685,675 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5887:Chl1
|
UTSW |
6 |
103,694,565 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5986:Chl1
|
UTSW |
6 |
103,686,152 (GRCm39) |
missense |
probably benign |
0.45 |
|
R6101:Chl1
|
UTSW |
6 |
103,669,993 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R6179:Chl1
|
UTSW |
6 |
103,660,204 (GRCm39) |
missense |
probably benign |
0.38 |
|
R6366:Chl1
|
UTSW |
6 |
103,706,197 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R6634:Chl1
|
UTSW |
6 |
103,667,220 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6824:Chl1
|
UTSW |
6 |
103,691,510 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6913:Chl1
|
UTSW |
6 |
103,642,909 (GRCm39) |
nonsense |
probably null |
|
|
R7122:Chl1
|
UTSW |
6 |
103,683,409 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7198:Chl1
|
UTSW |
6 |
103,683,517 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7203:Chl1
|
UTSW |
6 |
103,668,635 (GRCm39) |
missense |
probably benign |
0.13 |
|
R7527:Chl1
|
UTSW |
6 |
103,688,162 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7625:Chl1
|
UTSW |
6 |
103,706,086 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7667:Chl1
|
UTSW |
6 |
103,672,456 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R7683:Chl1
|
UTSW |
6 |
103,668,613 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R7712:Chl1
|
UTSW |
6 |
103,688,063 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R7838:Chl1
|
UTSW |
6 |
103,668,635 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7863:Chl1
|
UTSW |
6 |
103,683,475 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R7874:Chl1
|
UTSW |
6 |
103,667,224 (GRCm39) |
missense |
probably benign |
0.22 |
|
R7998:Chl1
|
UTSW |
6 |
103,706,250 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8044:Chl1
|
UTSW |
6 |
103,683,593 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R8059:Chl1
|
UTSW |
6 |
103,651,948 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R8462:Chl1
|
UTSW |
6 |
103,706,130 (GRCm39) |
missense |
probably benign |
0.11 |
|
R8558:Chl1
|
UTSW |
6 |
103,685,390 (GRCm39) |
missense |
probably benign |
0.14 |
|
R8827:Chl1
|
UTSW |
6 |
103,670,111 (GRCm39) |
missense |
probably benign |
|
|
R8865:Chl1
|
UTSW |
6 |
103,685,822 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8939:Chl1
|
UTSW |
6 |
103,642,868 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9092:Chl1
|
UTSW |
6 |
103,645,815 (GRCm39) |
unclassified |
probably benign |
|
|
Z1177:Chl1
|
UTSW |
6 |
103,674,910 (GRCm39) |
start gained |
probably benign |
|
|
Z1177:Chl1
|
UTSW |
6 |
103,670,057 (GRCm39) |
nonsense |
probably null |
|
|
Z1191:Chl1
|
UTSW |
6 |
103,660,172 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- CCATGTCTCAAAATAGTGGAAGATTGC -3'
(R):5'- TGAATAGAGTGTCACTGGCTG -3'
Sequencing Primer
(F):5'- AAAATAACAAATCTGCTTCTGACTTG -3'
(R):5'- AGTGTCACTGGCTGAGGGTC -3'
|
| Posted On |
2019-05-15 |
Incidental Mutation