Incidental Mutation 'R7107:Arap2'
| ID |
551227 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Arap2
|
| Ensembl Gene |
ENSMUSG00000037999 |
| Gene Name |
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 |
| Synonyms |
Centd1 |
| MMRRC Submission |
045199-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R7107 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
5 |
| Chromosomal Location |
62759788-62923502 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to A
at 62763551 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Histidine to Leucine
at position 1531
(H1531L)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000075924
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000076623]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000076623
AA Change: H1531L
PolyPhen 2
Score 0.984 (Sensitivity: 0.74; Specificity: 0.96)
|
| SMART Domains |
Protein: ENSMUSP00000075924
Gene: ENSMUSG00000037999
AA Change: H1531L
| Domain | Start | End | E-Value | Type |
|---|
|
SAM
|
3 |
70 |
3.69e-7 |
SMART |
|
low complexity region
|
222 |
233 |
N/A |
INTRINSIC |
|
PH
|
481 |
574 |
6.45e-17 |
SMART |
|
PH
|
586 |
679 |
9.05e-12 |
SMART |
|
ArfGap
|
684 |
805 |
9.2e-33 |
SMART |
|
PH
|
891 |
1003 |
1.51e-8 |
SMART |
|
PH
|
1013 |
1112 |
9.21e-4 |
SMART |
|
RhoGAP
|
1124 |
1300 |
1.36e-50 |
SMART |
|
Pfam:RA
|
1325 |
1416 |
2.1e-7 |
PFAM |
|
PH
|
1429 |
1533 |
2.68e-14 |
SMART |
|
coiled coil region
|
1561 |
1590 |
N/A |
INTRINSIC |
|
| Meta Mutation Damage Score |
0.8224 |
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 100.0%
- 10x: 99.7%
- 20x: 99.1%
|
| Validation Efficiency |
99% (78/79) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene contains ARF-GAP, RHO-GAP, ankyrin repeat, RAS-associating, and pleckstrin homology domains. The protein is a phosphatidylinositol (3,4,5)-trisphosphate-dependent Arf6 GAP that binds RhoA-GTP, but it lacks the predicted catalytic arginine in the RHO-GAP domain and does not have RHO-GAP activity. The protein associates with focal adhesions and functions downstream of RhoA to regulate focal adhesion dynamics. [provided by RefSeq, Sep 2008]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 80 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abca8b |
A |
G |
11: 109,867,299 (GRCm39) |
L253S |
probably damaging |
Het |
| Adgrv1 |
T |
C |
13: 81,726,261 (GRCm39) |
E588G |
probably benign |
Het |
| Ahcy |
G |
A |
2: 154,910,893 (GRCm39) |
A25V |
probably damaging |
Het |
| Ank2 |
A |
C |
3: 126,797,631 (GRCm39) |
L710R |
probably damaging |
Het |
| Ap1b1 |
A |
G |
11: 4,989,558 (GRCm39) |
T824A |
probably benign |
Het |
| Atosb |
A |
T |
4: 43,036,434 (GRCm39) |
V99E |
probably benign |
Het |
| B3gnt7 |
T |
C |
1: 86,233,495 (GRCm39) |
L247P |
probably damaging |
Het |
| Bcl6b |
A |
G |
11: 70,117,396 (GRCm39) |
C409R |
probably damaging |
Het |
| Bicdl1 |
T |
C |
5: 115,808,229 (GRCm39) |
H301R |
probably benign |
Het |
| Casc3 |
T |
A |
11: 98,718,413 (GRCm39) |
I491N |
possibly damaging |
Het |
| Ccdc92b |
T |
A |
11: 74,520,887 (GRCm39) |
L63Q |
probably damaging |
Het |
| Cep250 |
A |
G |
2: 155,837,314 (GRCm39) |
T2319A |
probably benign |
Het |
| Chd1 |
T |
C |
17: 15,981,628 (GRCm39) |
S1356P |
probably damaging |
Het |
| Chd8 |
A |
G |
14: 52,450,129 (GRCm39) |
S1542P |
probably benign |
Het |
| Clec2m |
A |
G |
6: 129,299,915 (GRCm39) |
C188R |
probably damaging |
Het |
| Cntnap4 |
A |
G |
8: 113,542,120 (GRCm39) |
D751G |
probably damaging |
Het |
| Cpsf4l |
G |
A |
11: 113,593,315 (GRCm39) |
R90C |
possibly damaging |
Het |
| Defa21 |
G |
A |
8: 21,515,724 (GRCm39) |
A41T |
probably damaging |
Het |
| Dennd4a |
G |
T |
9: 64,801,681 (GRCm39) |
L941F |
possibly damaging |
Het |
| Dnah12 |
G |
A |
14: 26,500,869 (GRCm39) |
|
probably null |
Het |
| Dtx4 |
A |
T |
19: 12,450,624 (GRCm39) |
C529* |
probably null |
Het |
| Entpd3 |
A |
G |
9: 120,389,665 (GRCm39) |
Y317C |
probably damaging |
Het |
| Erp29 |
T |
A |
5: 121,583,381 (GRCm39) |
I182F |
possibly damaging |
Het |
| Fam161a |
A |
G |
11: 22,973,452 (GRCm39) |
R445G |
possibly damaging |
Het |
| Fam76a |
T |
A |
4: 132,631,232 (GRCm39) |
M238L |
possibly damaging |
Het |
| Fn1 |
T |
C |
1: 71,666,408 (GRCm39) |
Y875C |
probably damaging |
Het |
| Gnb2 |
A |
G |
5: 137,528,444 (GRCm39) |
|
probably null |
Het |
| Hspg2 |
T |
C |
4: 137,237,963 (GRCm39) |
S229P |
probably damaging |
Het |
| Ighv6-6 |
A |
G |
12: 114,398,590 (GRCm39) |
S59P |
probably damaging |
Het |
| Itpkc |
C |
A |
7: 26,927,702 (GRCm39) |
A71S |
probably benign |
Het |
| Kcnk10 |
G |
A |
12: 98,485,002 (GRCm39) |
R45* |
probably null |
Het |
| Krcc1 |
A |
G |
6: 71,261,198 (GRCm39) |
S77G |
probably benign |
Het |
| Lelp1 |
G |
A |
3: 92,042,821 (GRCm39) |
T76I |
unknown |
Het |
| Lifr |
A |
T |
15: 7,208,421 (GRCm39) |
I600F |
possibly damaging |
Het |
| Lrrk1 |
T |
A |
7: 65,937,191 (GRCm39) |
D987V |
possibly damaging |
Het |
| Muc16 |
C |
T |
9: 18,548,594 (GRCm39) |
D5900N |
probably benign |
Het |
| Muc6 |
AGGCGCAGAAACCCTGGC |
AGGC |
7: 141,214,363 (GRCm39) |
|
probably null |
Het |
| Myo9a |
A |
G |
9: 59,778,098 (GRCm39) |
I1285V |
probably benign |
Het |
| Ndel1 |
T |
C |
11: 68,713,474 (GRCm39) |
D321G |
possibly damaging |
Het |
| Nlrp4b |
T |
C |
7: 10,449,144 (GRCm39) |
V449A |
probably damaging |
Het |
| Or10q12 |
A |
G |
19: 13,746,525 (GRCm39) |
E273G |
probably benign |
Het |
| Or2r11 |
T |
C |
6: 42,437,488 (GRCm39) |
N155S |
possibly damaging |
Het |
| Or2y1c |
T |
A |
11: 49,361,261 (GRCm39) |
Y94* |
probably null |
Het |
| Or51k1 |
A |
T |
7: 103,661,489 (GRCm39) |
L140Q |
probably benign |
Het |
| Or5k3 |
A |
C |
16: 58,969,279 (GRCm39) |
D22A |
probably benign |
Het |
| Osbpl1a |
G |
A |
18: 12,974,310 (GRCm39) |
R459* |
probably null |
Het |
| Pabpc1l |
A |
C |
2: 163,884,399 (GRCm39) |
T379P |
probably damaging |
Het |
| Pde2a |
A |
T |
7: 101,071,175 (GRCm39) |
Q15L |
probably benign |
Het |
| Pdk1 |
A |
G |
2: 71,726,085 (GRCm39) |
N331S |
probably benign |
Het |
| Pfdn1 |
A |
T |
18: 36,584,519 (GRCm39) |
|
probably null |
Het |
| Pnliprp1 |
T |
A |
19: 58,717,582 (GRCm39) |
L9H |
probably damaging |
Het |
| Prl7a2 |
A |
T |
13: 27,843,076 (GRCm39) |
D242E |
possibly damaging |
Het |
| Prmt9 |
T |
A |
8: 78,294,880 (GRCm39) |
I408N |
possibly damaging |
Het |
| Psme4 |
G |
A |
11: 30,798,105 (GRCm39) |
R1366H |
probably benign |
Het |
| Pstpip1 |
A |
T |
9: 56,035,934 (GRCm39) |
D393V |
probably damaging |
Het |
| Rab5b |
A |
G |
10: 128,519,062 (GRCm39) |
|
probably null |
Het |
| Rap1gap2 |
G |
A |
11: 74,283,945 (GRCm39) |
R618C |
probably damaging |
Het |
| Rin1 |
A |
G |
19: 5,100,801 (GRCm39) |
|
probably benign |
Het |
| Sall3 |
G |
A |
18: 81,016,969 (GRCm39) |
P320S |
probably benign |
Het |
| Sdk1 |
A |
G |
5: 142,067,471 (GRCm39) |
T1124A |
probably damaging |
Het |
| Sirpb1c |
T |
A |
3: 15,892,941 (GRCm39) |
T88S |
possibly damaging |
Het |
| Slc35f6 |
T |
A |
5: 30,814,121 (GRCm39) |
I189N |
probably damaging |
Het |
| Slc49a3 |
T |
A |
5: 108,596,581 (GRCm39) |
|
probably null |
Het |
| Spata31d1e |
T |
A |
13: 59,889,997 (GRCm39) |
R608* |
probably null |
Het |
| Spsb2 |
A |
T |
6: 124,787,244 (GRCm39) |
Q226L |
probably benign |
Het |
| Stab2 |
T |
C |
10: 86,741,456 (GRCm39) |
D1221G |
possibly damaging |
Het |
| Sugp1 |
G |
A |
8: 70,522,800 (GRCm39) |
R500H |
probably benign |
Het |
| Syne1 |
A |
G |
10: 5,082,078 (GRCm39) |
Y849H |
probably damaging |
Het |
| Tbck |
T |
A |
3: 132,428,092 (GRCm39) |
I249N |
possibly damaging |
Het |
| Tdrd6 |
A |
C |
17: 43,935,095 (GRCm39) |
F1984L |
probably benign |
Het |
| Tnxb |
T |
A |
17: 34,890,314 (GRCm39) |
V219E |
unknown |
Het |
| Tpst1 |
T |
A |
5: 130,143,344 (GRCm39) |
V294D |
probably damaging |
Het |
| Treml1 |
A |
G |
17: 48,667,247 (GRCm39) |
Q44R |
probably damaging |
Het |
| Trrap |
G |
A |
5: 144,733,945 (GRCm39) |
A933T |
probably benign |
Het |
| Vars2 |
A |
G |
17: 35,969,142 (GRCm39) |
L853P |
probably damaging |
Het |
| Vmn1r10 |
A |
T |
6: 57,090,615 (GRCm39) |
N69I |
possibly damaging |
Het |
| Vmn1r179 |
T |
A |
7: 23,627,819 (GRCm39) |
Y3* |
probably null |
Het |
| Vmn2r38 |
T |
A |
7: 9,093,728 (GRCm39) |
Y498F |
probably benign |
Het |
| Zc3h11a |
T |
C |
1: 133,566,655 (GRCm39) |
T179A |
probably damaging |
Het |
| Zmym2 |
A |
G |
14: 57,140,169 (GRCm39) |
T3A |
probably benign |
Het |
|
| Other mutations in Arap2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00481:Arap2
|
APN |
5 |
62,793,305 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00642:Arap2
|
APN |
5 |
62,890,401 (GRCm39) |
nonsense |
probably null |
|
|
IGL00705:Arap2
|
APN |
5 |
62,835,366 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00942:Arap2
|
APN |
5 |
62,855,732 (GRCm39) |
nonsense |
probably null |
|
|
IGL01069:Arap2
|
APN |
5 |
62,807,199 (GRCm39) |
missense |
probably benign |
|
|
IGL01601:Arap2
|
APN |
5 |
62,798,685 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01986:Arap2
|
APN |
5 |
62,779,265 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02032:Arap2
|
APN |
5 |
62,828,340 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02262:Arap2
|
APN |
5 |
62,800,184 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02331:Arap2
|
APN |
5 |
62,807,025 (GRCm39) |
splice site |
probably benign |
|
|
IGL02527:Arap2
|
APN |
5 |
62,906,650 (GRCm39) |
missense |
probably benign |
|
|
IGL02803:Arap2
|
APN |
5 |
62,906,452 (GRCm39) |
missense |
probably benign |
|
|
IGL02864:Arap2
|
APN |
5 |
62,835,308 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03078:Arap2
|
APN |
5 |
62,890,408 (GRCm39) |
splice site |
probably benign |
|
|
IGL03154:Arap2
|
APN |
5 |
62,800,268 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03213:Arap2
|
APN |
5 |
62,906,438 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL03279:Arap2
|
APN |
5 |
62,779,253 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03288:Arap2
|
APN |
5 |
62,761,959 (GRCm39) |
missense |
probably benign |
0.00 |
|
PIT4354001:Arap2
|
UTSW |
5 |
62,811,392 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0012:Arap2
|
UTSW |
5 |
62,840,827 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0013:Arap2
|
UTSW |
5 |
62,840,827 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0013:Arap2
|
UTSW |
5 |
62,840,827 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0166:Arap2
|
UTSW |
5 |
62,833,361 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0472:Arap2
|
UTSW |
5 |
62,864,002 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0506:Arap2
|
UTSW |
5 |
62,763,474 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R0551:Arap2
|
UTSW |
5 |
62,798,666 (GRCm39) |
splice site |
probably null |
|
|
R0607:Arap2
|
UTSW |
5 |
62,763,474 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R0617:Arap2
|
UTSW |
5 |
62,807,250 (GRCm39) |
splice site |
probably benign |
|
|
R0975:Arap2
|
UTSW |
5 |
62,888,229 (GRCm39) |
splice site |
probably benign |
|
|
R0976:Arap2
|
UTSW |
5 |
62,807,227 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1164:Arap2
|
UTSW |
5 |
62,840,820 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1268:Arap2
|
UTSW |
5 |
62,887,964 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1480:Arap2
|
UTSW |
5 |
62,826,472 (GRCm39) |
nonsense |
probably null |
|
|
R1502:Arap2
|
UTSW |
5 |
62,761,747 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1543:Arap2
|
UTSW |
5 |
62,763,498 (GRCm39) |
nonsense |
probably null |
|
|
R1865:Arap2
|
UTSW |
5 |
62,855,606 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R1962:Arap2
|
UTSW |
5 |
62,834,007 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R2040:Arap2
|
UTSW |
5 |
62,906,259 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2118:Arap2
|
UTSW |
5 |
62,864,028 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2131:Arap2
|
UTSW |
5 |
62,835,301 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2201:Arap2
|
UTSW |
5 |
62,864,028 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2215:Arap2
|
UTSW |
5 |
62,834,519 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3027:Arap2
|
UTSW |
5 |
62,827,240 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3053:Arap2
|
UTSW |
5 |
62,906,200 (GRCm39) |
missense |
probably benign |
0.35 |
|
R3975:Arap2
|
UTSW |
5 |
62,906,237 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R4272:Arap2
|
UTSW |
5 |
62,828,322 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R4273:Arap2
|
UTSW |
5 |
62,828,322 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R4326:Arap2
|
UTSW |
5 |
62,779,206 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R4327:Arap2
|
UTSW |
5 |
62,779,206 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R4328:Arap2
|
UTSW |
5 |
62,779,206 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R4451:Arap2
|
UTSW |
5 |
62,906,513 (GRCm39) |
missense |
probably benign |
0.06 |
|
R4659:Arap2
|
UTSW |
5 |
62,811,469 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R4665:Arap2
|
UTSW |
5 |
62,827,312 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R4715:Arap2
|
UTSW |
5 |
62,906,437 (GRCm39) |
missense |
probably benign |
0.43 |
|
R4808:Arap2
|
UTSW |
5 |
62,887,984 (GRCm39) |
missense |
probably benign |
0.23 |
|
R4941:Arap2
|
UTSW |
5 |
62,906,821 (GRCm39) |
missense |
probably benign |
0.20 |
|
R4983:Arap2
|
UTSW |
5 |
62,833,868 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5095:Arap2
|
UTSW |
5 |
62,811,392 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5156:Arap2
|
UTSW |
5 |
62,826,524 (GRCm39) |
nonsense |
probably null |
|
|
R5201:Arap2
|
UTSW |
5 |
62,840,832 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5346:Arap2
|
UTSW |
5 |
62,872,089 (GRCm39) |
missense |
probably benign |
0.39 |
|
R5359:Arap2
|
UTSW |
5 |
62,840,762 (GRCm39) |
nonsense |
probably null |
|
|
R5426:Arap2
|
UTSW |
5 |
62,800,159 (GRCm39) |
missense |
probably benign |
0.02 |
|
R5503:Arap2
|
UTSW |
5 |
62,787,529 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5605:Arap2
|
UTSW |
5 |
62,772,410 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
R5764:Arap2
|
UTSW |
5 |
62,800,197 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5813:Arap2
|
UTSW |
5 |
62,834,506 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5846:Arap2
|
UTSW |
5 |
62,807,116 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6084:Arap2
|
UTSW |
5 |
62,828,297 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R6173:Arap2
|
UTSW |
5 |
62,906,965 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6175:Arap2
|
UTSW |
5 |
62,872,074 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6249:Arap2
|
UTSW |
5 |
62,803,536 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6386:Arap2
|
UTSW |
5 |
62,761,865 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R6424:Arap2
|
UTSW |
5 |
62,840,707 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6744:Arap2
|
UTSW |
5 |
62,906,281 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6766:Arap2
|
UTSW |
5 |
62,834,443 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6990:Arap2
|
UTSW |
5 |
62,833,860 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7067:Arap2
|
UTSW |
5 |
62,811,387 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7098:Arap2
|
UTSW |
5 |
62,833,293 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7156:Arap2
|
UTSW |
5 |
62,761,914 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7174:Arap2
|
UTSW |
5 |
62,761,621 (GRCm39) |
missense |
probably benign |
|
|
R7187:Arap2
|
UTSW |
5 |
62,826,396 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7197:Arap2
|
UTSW |
5 |
62,798,729 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R7214:Arap2
|
UTSW |
5 |
62,906,681 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7317:Arap2
|
UTSW |
5 |
62,807,067 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7392:Arap2
|
UTSW |
5 |
62,855,728 (GRCm39) |
missense |
possibly damaging |
0.54 |
|
R7438:Arap2
|
UTSW |
5 |
62,906,818 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7452:Arap2
|
UTSW |
5 |
62,833,892 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7495:Arap2
|
UTSW |
5 |
62,833,893 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R7796:Arap2
|
UTSW |
5 |
62,888,105 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7936:Arap2
|
UTSW |
5 |
62,888,048 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R8116:Arap2
|
UTSW |
5 |
62,887,954 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8172:Arap2
|
UTSW |
5 |
62,779,324 (GRCm39) |
splice site |
probably null |
|
|
R8277:Arap2
|
UTSW |
5 |
62,771,335 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8369:Arap2
|
UTSW |
5 |
62,761,669 (GRCm39) |
nonsense |
probably null |
|
|
R8398:Arap2
|
UTSW |
5 |
62,906,252 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8893:Arap2
|
UTSW |
5 |
62,888,037 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8973:Arap2
|
UTSW |
5 |
62,855,668 (GRCm39) |
nonsense |
probably null |
|
|
R9102:Arap2
|
UTSW |
5 |
62,906,341 (GRCm39) |
missense |
probably benign |
0.03 |
|
R9121:Arap2
|
UTSW |
5 |
62,906,326 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R9174:Arap2
|
UTSW |
5 |
62,855,606 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9222:Arap2
|
UTSW |
5 |
62,828,421 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R9281:Arap2
|
UTSW |
5 |
62,906,848 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R9399:Arap2
|
UTSW |
5 |
62,763,455 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
R9450:Arap2
|
UTSW |
5 |
62,855,762 (GRCm39) |
missense |
probably benign |
0.16 |
|
R9467:Arap2
|
UTSW |
5 |
62,887,900 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9567:Arap2
|
UTSW |
5 |
62,761,841 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9577:Arap2
|
UTSW |
5 |
62,769,060 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9626:Arap2
|
UTSW |
5 |
62,906,878 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9688:Arap2
|
UTSW |
5 |
62,872,109 (GRCm39) |
missense |
probably damaging |
0.98 |
|
| Predicted Primers |
PCR Primer
(F):5'- TTGTTGCTAGGCACCAGAAGC -3'
(R):5'- GAGACCTCAAAGCTCAGTTCAC -3'
Sequencing Primer
(F):5'- GTAATTAATACACCCAGCCATGTG -3'
(R):5'- ACTTAAGTGTTTCACATCCCGGAG -3'
|
| Posted On |
2019-05-15 |
Incidental Mutation