Incidental Mutation 'R7108:Ralgapb'
| ID |
551298 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Ralgapb
|
| Ensembl Gene |
ENSMUSG00000027652 |
| Gene Name |
Ral GTPase activating protein, beta subunit (non-catalytic) |
| Synonyms |
B230339M05Rik |
| MMRRC Submission |
045200-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R7108 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
2 |
| Chromosomal Location |
158251768-158341173 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 158334380 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Tyrosine to Histidine
at position 1364
(Y1364H)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000105111
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000046274]
[ENSMUST00000109485]
[ENSMUST00000109486]
[ENSMUST00000141497]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000046274
AA Change: Y1348H
PolyPhen 2
Score 0.957 (Sensitivity: 0.78; Specificity: 0.95)
|
| SMART Domains |
Protein: ENSMUSP00000048430
Gene: ENSMUSG00000027652
AA Change: Y1348H
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
166 |
178 |
N/A |
INTRINSIC |
|
low complexity region
|
610 |
625 |
N/A |
INTRINSIC |
|
low complexity region
|
775 |
788 |
N/A |
INTRINSIC |
|
low complexity region
|
910 |
920 |
N/A |
INTRINSIC |
|
low complexity region
|
1086 |
1097 |
N/A |
INTRINSIC |
|
low complexity region
|
1309 |
1321 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000109485
AA Change: Y1364H
PolyPhen 2
Score 0.980 (Sensitivity: 0.75; Specificity: 0.96)
|
| SMART Domains |
Protein: ENSMUSP00000105111
Gene: ENSMUSG00000027652
AA Change: Y1364H
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
166 |
178 |
N/A |
INTRINSIC |
|
low complexity region
|
622 |
637 |
N/A |
INTRINSIC |
|
low complexity region
|
791 |
804 |
N/A |
INTRINSIC |
|
low complexity region
|
926 |
936 |
N/A |
INTRINSIC |
|
low complexity region
|
1102 |
1113 |
N/A |
INTRINSIC |
|
low complexity region
|
1325 |
1337 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000109486
AA Change: Y1352H
PolyPhen 2
Score 0.957 (Sensitivity: 0.78; Specificity: 0.95)
|
| SMART Domains |
Protein: ENSMUSP00000105112
Gene: ENSMUSG00000027652
AA Change: Y1352H
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
166 |
178 |
N/A |
INTRINSIC |
|
low complexity region
|
610 |
625 |
N/A |
INTRINSIC |
|
low complexity region
|
779 |
792 |
N/A |
INTRINSIC |
|
low complexity region
|
914 |
924 |
N/A |
INTRINSIC |
|
low complexity region
|
1090 |
1101 |
N/A |
INTRINSIC |
|
low complexity region
|
1313 |
1325 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000141497
AA Change: Y1030H
PolyPhen 2
Score 0.976 (Sensitivity: 0.76; Specificity: 0.96)
|
| SMART Domains |
Protein: ENSMUSP00000116481
Gene: ENSMUSG00000027652
AA Change: Y1030H
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
288 |
303 |
N/A |
INTRINSIC |
|
low complexity region
|
457 |
470 |
N/A |
INTRINSIC |
|
low complexity region
|
592 |
602 |
N/A |
INTRINSIC |
|
low complexity region
|
768 |
779 |
N/A |
INTRINSIC |
|
low complexity region
|
991 |
1003 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 100.0%
- 10x: 99.7%
- 20x: 99.0%
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 79 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 2810021J22Rik |
T |
C |
11: 58,771,750 (GRCm39) |
S411P |
probably damaging |
Het |
| 4930503L19Rik |
A |
T |
18: 70,601,547 (GRCm39) |
Y112N |
probably benign |
Het |
| Abcd2 |
A |
T |
15: 91,075,477 (GRCm39) |
V112E |
probably benign |
Het |
| Acadm |
A |
T |
3: 153,631,437 (GRCm39) |
Y353* |
probably null |
Het |
| Adra2c |
A |
G |
5: 35,437,342 (GRCm39) |
D38G |
probably benign |
Het |
| Ankrd10 |
C |
T |
8: 11,662,624 (GRCm39) |
G370R |
probably damaging |
Het |
| Arfgef2 |
T |
A |
2: 166,715,528 (GRCm39) |
N1324K |
possibly damaging |
Het |
| Atp6v1b2 |
A |
G |
8: 69,555,153 (GRCm39) |
T172A |
probably damaging |
Het |
| Bloc1s1 |
T |
A |
10: 128,758,592 (GRCm39) |
K22M |
possibly damaging |
Het |
| Brpf3 |
A |
G |
17: 29,036,099 (GRCm39) |
T599A |
probably benign |
Het |
| Cacna1e |
TTCCAGTCTC |
TTC |
1: 154,344,741 (GRCm39) |
|
probably null |
Het |
| Ccdc186 |
T |
C |
19: 56,787,192 (GRCm39) |
D592G |
probably damaging |
Het |
| Cfap161 |
A |
T |
7: 83,442,518 (GRCm39) |
D98E |
possibly damaging |
Het |
| Cfi |
G |
A |
3: 129,668,665 (GRCm39) |
V564M |
probably damaging |
Het |
| Cilp2 |
T |
A |
8: 70,333,779 (GRCm39) |
Q1073L |
probably damaging |
Het |
| Cox6b1 |
A |
G |
7: 30,322,929 (GRCm39) |
C40R |
possibly damaging |
Het |
| Cyp3a59 |
A |
T |
5: 146,033,143 (GRCm39) |
M172L |
probably benign |
Het |
| Cyth1 |
T |
C |
11: 118,073,739 (GRCm39) |
D198G |
probably damaging |
Het |
| Daam2 |
T |
C |
17: 49,767,702 (GRCm39) |
D963G |
probably damaging |
Het |
| Ddi2 |
A |
T |
4: 141,433,248 (GRCm39) |
D209E |
probably benign |
Het |
| Dnah12 |
G |
A |
14: 26,500,869 (GRCm39) |
|
probably null |
Het |
| Dnai7 |
G |
A |
6: 145,131,591 (GRCm39) |
Q351* |
probably null |
Het |
| Dpagt1 |
G |
T |
9: 44,238,318 (GRCm39) |
|
probably benign |
Het |
| Drc3 |
T |
A |
11: 60,261,380 (GRCm39) |
F177Y |
probably benign |
Het |
| Dsg2 |
T |
C |
18: 20,734,920 (GRCm39) |
V966A |
probably damaging |
Het |
| E4f1 |
A |
G |
17: 24,663,552 (GRCm39) |
V633A |
probably damaging |
Het |
| Eif2ak2 |
T |
A |
17: 79,165,965 (GRCm39) |
R411* |
probably null |
Het |
| Frem2 |
T |
C |
3: 53,560,934 (GRCm39) |
E1191G |
probably damaging |
Het |
| Fry |
T |
C |
5: 150,319,251 (GRCm39) |
V972A |
probably damaging |
Het |
| Fry |
T |
A |
5: 150,414,555 (GRCm39) |
C467S |
|
Het |
| Fscn1 |
T |
C |
5: 142,946,270 (GRCm39) |
Y23H |
probably damaging |
Het |
| Gm16506 |
T |
A |
14: 43,961,759 (GRCm39) |
I163F |
|
Het |
| Gm21103 |
T |
C |
14: 17,484,768 (GRCm39) |
Y92C |
probably damaging |
Het |
| Golgb1 |
A |
G |
16: 36,734,083 (GRCm39) |
H1151R |
probably benign |
Het |
| Gprc5c |
T |
C |
11: 114,755,108 (GRCm39) |
Y262H |
probably damaging |
Het |
| Hc |
G |
T |
2: 34,929,706 (GRCm39) |
N245K |
probably benign |
Het |
| Hps6 |
T |
A |
19: 45,993,929 (GRCm39) |
L622Q |
probably damaging |
Het |
| Hsd17b1 |
T |
C |
11: 100,970,035 (GRCm39) |
Y156H |
probably damaging |
Het |
| Ireb2 |
T |
A |
9: 54,813,925 (GRCm39) |
F799L |
probably damaging |
Het |
| Irf1 |
A |
G |
11: 53,665,238 (GRCm39) |
D205G |
probably damaging |
Het |
| Kif12 |
A |
T |
4: 63,089,442 (GRCm39) |
F103L |
probably benign |
Het |
| Krt12 |
C |
T |
11: 99,306,878 (GRCm39) |
V475M |
unknown |
Het |
| Lca5 |
T |
A |
9: 83,305,222 (GRCm39) |
T195S |
probably benign |
Het |
| Lrrc17 |
T |
C |
5: 21,780,337 (GRCm39) |
V437A |
possibly damaging |
Het |
| Malt1 |
G |
T |
18: 65,597,122 (GRCm39) |
D468Y |
probably damaging |
Het |
| Man2b2 |
C |
T |
5: 36,972,829 (GRCm39) |
A562T |
probably benign |
Het |
| Mrc1 |
C |
T |
2: 14,308,957 (GRCm39) |
Q794* |
probably null |
Het |
| Muc16 |
T |
A |
9: 18,566,529 (GRCm39) |
I1997L |
unknown |
Het |
| Muc6 |
AGGCGCAGAAACCCTGGC |
AGGC |
7: 141,214,363 (GRCm39) |
|
probably null |
Het |
| Mycbp2 |
A |
T |
14: 103,360,039 (GRCm39) |
F4518Y |
probably damaging |
Het |
| Myo5a |
T |
A |
9: 75,037,274 (GRCm39) |
I159N |
probably damaging |
Het |
| Nat1 |
T |
C |
8: 67,943,672 (GRCm39) |
V19A |
probably benign |
Het |
| Ndst4 |
A |
G |
3: 125,355,120 (GRCm39) |
T343A |
probably damaging |
Het |
| Nlrp9b |
A |
T |
7: 19,779,855 (GRCm39) |
L839F |
probably damaging |
Het |
| Nxnl1 |
A |
G |
8: 72,019,198 (GRCm39) |
I9T |
probably benign |
Het |
| Odr4 |
T |
C |
1: 150,258,041 (GRCm39) |
Y198C |
probably benign |
Het |
| Or1l4b |
C |
T |
2: 37,036,272 (GRCm39) |
T16I |
probably benign |
Het |
| Or2ag12 |
G |
A |
7: 106,277,255 (GRCm39) |
A146V |
probably benign |
Het |
| Or2t49 |
T |
A |
11: 58,393,380 (GRCm39) |
M7L |
probably benign |
Het |
| Or52b4i |
A |
T |
7: 102,191,199 (GRCm39) |
I19F |
probably damaging |
Het |
| Or7a35 |
C |
A |
10: 78,853,483 (GRCm39) |
S109* |
probably null |
Het |
| Pou5f2 |
T |
C |
13: 78,173,384 (GRCm39) |
S109P |
possibly damaging |
Het |
| Prkcz |
G |
A |
4: 155,371,250 (GRCm39) |
Q321* |
probably null |
Het |
| Prr18 |
G |
T |
17: 8,560,363 (GRCm39) |
R173L |
probably damaging |
Het |
| Sacs |
T |
A |
14: 61,448,458 (GRCm39) |
Y3501* |
probably null |
Het |
| Sall3 |
G |
A |
18: 81,016,969 (GRCm39) |
P320S |
probably benign |
Het |
| Scn8a |
A |
T |
15: 100,937,659 (GRCm39) |
H1676L |
probably benign |
Het |
| Shmt1 |
T |
C |
11: 60,689,470 (GRCm39) |
D178G |
probably damaging |
Het |
| Slmap |
T |
C |
14: 26,143,676 (GRCm39) |
K737R |
probably benign |
Het |
| Ssh2 |
G |
A |
11: 77,345,620 (GRCm39) |
V1202I |
probably benign |
Het |
| Stard7 |
A |
G |
2: 127,137,414 (GRCm39) |
D288G |
possibly damaging |
Het |
| Tek |
A |
T |
4: 94,741,724 (GRCm39) |
D827V |
probably damaging |
Het |
| Tfap2e |
A |
G |
4: 126,614,356 (GRCm39) |
L276P |
probably damaging |
Het |
| Tns3 |
T |
C |
11: 8,387,251 (GRCm39) |
N1312S |
probably benign |
Het |
| Tubd1 |
T |
A |
11: 86,448,631 (GRCm39) |
S315T |
probably damaging |
Het |
| Ube2f |
T |
A |
1: 91,192,941 (GRCm39) |
C50* |
probably null |
Het |
| Vmn2r109 |
T |
C |
17: 20,785,006 (GRCm39) |
I5V |
probably benign |
Het |
| Vmn2r39 |
T |
C |
7: 9,026,667 (GRCm39) |
T445A |
probably damaging |
Het |
| Zfp764l1 |
A |
G |
7: 126,990,695 (GRCm39) |
S431P |
probably benign |
Het |
|
| Other mutations in Ralgapb |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00094:Ralgapb
|
APN |
2 |
158,262,776 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00534:Ralgapb
|
APN |
2 |
158,272,420 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
IGL01362:Ralgapb
|
APN |
2 |
158,277,385 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01653:Ralgapb
|
APN |
2 |
158,304,079 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
IGL01704:Ralgapb
|
APN |
2 |
158,262,795 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
IGL02000:Ralgapb
|
APN |
2 |
158,296,034 (GRCm39) |
splice site |
probably benign |
|
|
IGL02169:Ralgapb
|
APN |
2 |
158,268,124 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02516:Ralgapb
|
APN |
2 |
158,307,735 (GRCm39) |
splice site |
probably benign |
|
|
IGL02548:Ralgapb
|
APN |
2 |
158,286,585 (GRCm39) |
missense |
probably damaging |
0.97 |
|
IGL02550:Ralgapb
|
APN |
2 |
158,290,331 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02653:Ralgapb
|
APN |
2 |
158,285,229 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02744:Ralgapb
|
APN |
2 |
158,288,071 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02804:Ralgapb
|
APN |
2 |
158,268,204 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
IGL02937:Ralgapb
|
APN |
2 |
158,334,936 (GRCm39) |
splice site |
probably null |
|
|
IGL02993:Ralgapb
|
APN |
2 |
158,279,314 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
IGL03154:Ralgapb
|
APN |
2 |
158,274,786 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03204:Ralgapb
|
APN |
2 |
158,307,832 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
IGL03347:Ralgapb
|
APN |
2 |
158,307,880 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
Chacha
|
UTSW |
2 |
158,334,372 (GRCm39) |
missense |
probably damaging |
0.99 |
|
Gato
|
UTSW |
2 |
158,286,540 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Kibble
|
UTSW |
2 |
158,279,060 (GRCm39) |
missense |
probably damaging |
1.00 |
|
ralston
|
UTSW |
2 |
158,296,197 (GRCm39) |
missense |
probably damaging |
1.00 |
|
PIT4142001:Ralgapb
|
UTSW |
2 |
158,272,342 (GRCm39) |
missense |
probably benign |
0.34 |
|
R0037:Ralgapb
|
UTSW |
2 |
158,279,331 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0037:Ralgapb
|
UTSW |
2 |
158,279,331 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0077:Ralgapb
|
UTSW |
2 |
158,315,169 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0581:Ralgapb
|
UTSW |
2 |
158,334,881 (GRCm39) |
missense |
probably benign |
|
|
R0629:Ralgapb
|
UTSW |
2 |
158,281,467 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0839:Ralgapb
|
UTSW |
2 |
158,315,203 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1331:Ralgapb
|
UTSW |
2 |
158,272,453 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1468:Ralgapb
|
UTSW |
2 |
158,304,173 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R1468:Ralgapb
|
UTSW |
2 |
158,304,173 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R1540:Ralgapb
|
UTSW |
2 |
158,307,746 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1572:Ralgapb
|
UTSW |
2 |
158,288,119 (GRCm39) |
splice site |
probably benign |
|
|
R1628:Ralgapb
|
UTSW |
2 |
158,272,383 (GRCm39) |
missense |
probably benign |
0.04 |
|
R1718:Ralgapb
|
UTSW |
2 |
158,285,200 (GRCm39) |
nonsense |
probably null |
|
|
R1777:Ralgapb
|
UTSW |
2 |
158,304,115 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1822:Ralgapb
|
UTSW |
2 |
158,334,372 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1903:Ralgapb
|
UTSW |
2 |
158,337,483 (GRCm39) |
missense |
probably benign |
0.04 |
|
R1909:Ralgapb
|
UTSW |
2 |
158,286,595 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2157:Ralgapb
|
UTSW |
2 |
158,279,392 (GRCm39) |
missense |
probably benign |
0.15 |
|
R4524:Ralgapb
|
UTSW |
2 |
158,279,226 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4946:Ralgapb
|
UTSW |
2 |
158,282,887 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4975:Ralgapb
|
UTSW |
2 |
158,277,428 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R5014:Ralgapb
|
UTSW |
2 |
158,337,455 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5165:Ralgapb
|
UTSW |
2 |
158,307,832 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
R5465:Ralgapb
|
UTSW |
2 |
158,290,325 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R5526:Ralgapb
|
UTSW |
2 |
158,274,705 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5566:Ralgapb
|
UTSW |
2 |
158,336,630 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R5949:Ralgapb
|
UTSW |
2 |
158,296,179 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6140:Ralgapb
|
UTSW |
2 |
158,298,492 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6175:Ralgapb
|
UTSW |
2 |
158,288,075 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6192:Ralgapb
|
UTSW |
2 |
158,291,367 (GRCm39) |
splice site |
probably null |
|
|
R6364:Ralgapb
|
UTSW |
2 |
158,304,029 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6458:Ralgapb
|
UTSW |
2 |
158,286,540 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6746:Ralgapb
|
UTSW |
2 |
158,318,056 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6782:Ralgapb
|
UTSW |
2 |
158,278,486 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6788:Ralgapb
|
UTSW |
2 |
158,278,486 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7017:Ralgapb
|
UTSW |
2 |
158,290,257 (GRCm39) |
missense |
probably benign |
0.19 |
|
R7108:Ralgapb
|
UTSW |
2 |
158,336,582 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7236:Ralgapb
|
UTSW |
2 |
158,282,747 (GRCm39) |
missense |
probably benign |
0.34 |
|
R7454:Ralgapb
|
UTSW |
2 |
158,274,822 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R7485:Ralgapb
|
UTSW |
2 |
158,285,275 (GRCm39) |
missense |
probably benign |
0.35 |
|
R7595:Ralgapb
|
UTSW |
2 |
158,268,085 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R7615:Ralgapb
|
UTSW |
2 |
158,292,190 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7728:Ralgapb
|
UTSW |
2 |
158,324,423 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7913:Ralgapb
|
UTSW |
2 |
158,307,859 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7953:Ralgapb
|
UTSW |
2 |
158,307,803 (GRCm39) |
missense |
probably benign |
0.10 |
|
R8245:Ralgapb
|
UTSW |
2 |
158,285,256 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R8337:Ralgapb
|
UTSW |
2 |
158,292,192 (GRCm39) |
missense |
probably benign |
0.11 |
|
R8363:Ralgapb
|
UTSW |
2 |
158,268,119 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8429:Ralgapb
|
UTSW |
2 |
158,268,217 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8673:Ralgapb
|
UTSW |
2 |
158,292,133 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8955:Ralgapb
|
UTSW |
2 |
158,337,389 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8955:Ralgapb
|
UTSW |
2 |
158,279,264 (GRCm39) |
missense |
probably benign |
0.05 |
|
R8992:Ralgapb
|
UTSW |
2 |
158,296,197 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9013:Ralgapb
|
UTSW |
2 |
158,279,060 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9141:Ralgapb
|
UTSW |
2 |
158,262,811 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R9166:Ralgapb
|
UTSW |
2 |
158,274,842 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9242:Ralgapb
|
UTSW |
2 |
158,277,386 (GRCm39) |
missense |
probably benign |
0.13 |
|
R9274:Ralgapb
|
UTSW |
2 |
158,278,539 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9354:Ralgapb
|
UTSW |
2 |
158,279,313 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R9454:Ralgapb
|
UTSW |
2 |
158,315,072 (GRCm39) |
missense |
probably benign |
0.30 |
|
R9489:Ralgapb
|
UTSW |
2 |
158,268,283 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R9490:Ralgapb
|
UTSW |
2 |
158,334,350 (GRCm39) |
missense |
probably benign |
0.29 |
|
R9510:Ralgapb
|
UTSW |
2 |
158,285,856 (GRCm39) |
missense |
probably damaging |
0.98 |
|
Z1177:Ralgapb
|
UTSW |
2 |
158,277,475 (GRCm39) |
missense |
probably benign |
0.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- TGGCTTTGGTGACATAAACACATC -3'
(R):5'- GCTGAGGTTCTAACATTGCTTACAC -3'
Sequencing Primer
(F):5'- TGGTGACATAAACACATCACTAATC -3'
(R):5'- GGTTCTAACATTGCTTACACAAAAAC -3'
|
| Posted On |
2019-05-15 |
Incidental Mutation