Mutagenetix > Incidental Mutation

Incidental Mutation 'R7125:Dnah2'

552276

Institutional Source

Beutler Lab

Gene Symbol

Dnah2

Ensembl Gene

ENSMUSG00000005237

Gene Name

dynein, axonemal, heavy chain 2

Synonyms

2900022L05Rik, D330014H01Rik, Dnahc2, Dnhd3

MMRRC Submission

045327-MU

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

R7125 (G1)

Quality Score

225.009

Status

Validated

Chromosome

Chromosomal Location

69311635-69439934 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

T to C at 69327008 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Threonine to Alanine at position 3533 (T3533A)

Ref Sequence

ENSEMBL: ENSMUSP00000104299 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000035539] [ENSMUST00000108659]

AlphaFold

no structure available at present

Predicted Effect

possibly damaging
Transcript: ENSMUST00000035539
AA Change: T3527A

PolyPhen 2 Score 0.779 (Sensitivity: 0.85; Specificity: 0.93)

SMART Domains

Protein: ENSMUSP00000047329
Gene: ENSMUSG00000005237
AA Change: T3527A

Domain	Start	End	E-Value	Type
low complexity region	4	25	N/A	INTRINSIC
Pfam:DHC_N1	273	429	6.6e-37	PFAM
Pfam:DHC_N1	432	761	1.3e-54	PFAM
Pfam:DHC_N2	1253	1668	3.4e-144	PFAM
AAA	1826	1962	2.95e-1	SMART
Pfam:AAA_5	2108	2251	1.3e-5	PFAM
AAA	2437	2584	3.63e-5	SMART
Pfam:AAA_8	2752	3022	1.1e-75	PFAM
Pfam:MT	3034	3370	8.7e-55	PFAM
Pfam:AAA_9	3386	3616	7.4e-68	PFAM
Pfam:Dynein_heavy	3748	4453	1.2e-220	PFAM

Predicted Effect

probably damaging
Transcript: ENSMUST00000108659
AA Change: T3533A

PolyPhen 2 Score 0.994 (Sensitivity: 0.69; Specificity: 0.97)

SMART Domains

Protein: ENSMUSP00000104299
Gene: ENSMUSG00000005237
AA Change: T3533A

Domain	Start	End	E-Value	Type
low complexity region	4	25	N/A	INTRINSIC
Pfam:DHC_N1	274	429	1.1e-47	PFAM
Pfam:DHC_N1	438	760	1.5e-75	PFAM
Pfam:DHC_N2	1255	1666	4.4e-144	PFAM
low complexity region	1711	1720	N/A	INTRINSIC
AAA	1832	1968	2.95e-1	SMART
Blast:AAA	2111	2251	2e-86	BLAST
AAA	2443	2590	3.63e-5	SMART
Pfam:AAA_8	2758	3028	5.5e-77	PFAM
Pfam:MT	3040	3376	7.6e-55	PFAM
Pfam:AAA_9	3396	3621	7.5e-94	PFAM
Pfam:Dynein_heavy	3759	4458	4.9e-264	PFAM

Coding Region Coverage

1x: 100.0%
3x: 100.0%
10x: 99.8%
20x: 99.2%

Validation Efficiency

96% (48/50)

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] Dyneins are microtubule-associated motor protein complexes composed of several heavy, light, and intermediate chains. The axonemal dyneins, found in cilia and flagella, are components of the outer and inner dynein arms attached to the peripheral microtubule doublets. DNAH2 is an axonemal inner arm dynein heavy chain (Chapelin et al., 1997 [PubMed 9256245]).[supplied by OMIM, Mar 2008]

Allele List at MGI

Other mutations in this stock

Total: 50 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
5730455P16Rik	A	T	11: 80,255,751 (GRCm39)	C296S	probably damaging	Het
Ago3	T	C	4: 126,264,145 (GRCm39)	I354V	probably null	Het
Aldh1l1	G	A	6: 90,553,761 (GRCm39)		probably null	Het
Ankrd49	TAA	TA	9: 14,693,836 (GRCm39)		probably null	Het
B3gnt7	A	G	1: 86,233,099 (GRCm39)	Y115C	probably damaging	Het
Cacna1h	A	T	17: 25,602,510 (GRCm39)	M1506K	probably damaging	Het
Cars1	T	C	7: 143,138,510 (GRCm39)	T226A	probably benign	Het
Ccdc28b	T	A	4: 129,514,885 (GRCm39)	T75S	probably benign	Het
Cdc42bpg	A	G	19: 6,372,321 (GRCm39)	I1436V	probably damaging	Het
Cep152	A	T	2: 125,408,593 (GRCm39)	Y1320*	probably null	Het
Cntnap2	A	T	6: 46,965,580 (GRCm39)	Y797F	probably benign	Het
Coq8a	T	A	1: 179,996,366 (GRCm39)	N490I	probably damaging	Het
Csmd2	T	C	4: 128,389,955 (GRCm39)	L2230P		Het
Cyp4a14	A	T	4: 115,348,358 (GRCm39)	I373N	probably damaging	Het
Ddx1	A	G	12: 13,293,864 (GRCm39)	S86P	probably benign	Het
Dennd3	A	T	15: 73,405,140 (GRCm39)	I298F	possibly damaging	Het
Disp1	C	A	1: 182,869,030 (GRCm39)	R1130L	probably damaging	Het
Fam53b	T	C	7: 132,373,357 (GRCm39)	H27R	probably damaging	Het
Firrm	T	C	1: 163,789,631 (GRCm39)	T635A	probably benign	Het
Fyb1	G	A	15: 6,674,337 (GRCm39)	E658K	possibly damaging	Het
Gapvd1	T	C	2: 34,585,612 (GRCm39)	S996G	probably benign	Het
Gm47959	G	A	1: 82,978,503 (GRCm39)	G57S	unknown	Het
Golgb1	T	A	16: 36,738,325 (GRCm39)	H2262Q	possibly damaging	Het
Gpam	T	C	19: 55,064,767 (GRCm39)	T646A	probably benign	Het
Gpt2	G	A	8: 86,244,681 (GRCm39)	E325K	probably benign	Het
Hexd	C	T	11: 121,095,496 (GRCm39)		probably benign	Het
Micu2	A	T	14: 58,209,238 (GRCm39)	Y73*	probably null	Het
N4bp2l2	T	C	5: 150,573,894 (GRCm39)		probably null	Het
Or11h7	T	C	14: 50,891,041 (GRCm39)	C116R	possibly damaging	Het
Or1e31	T	C	11: 73,689,990 (GRCm39)	M198V	probably benign	Het
Or1m1	A	T	9: 18,666,174 (GRCm39)	Y252*	probably null	Het
Or51t4	T	C	7: 102,598,386 (GRCm39)	V238A	probably damaging	Het
Or5b112	A	T	19: 13,319,103 (GRCm39)		probably null	Het
P3r3urf	A	G	4: 116,030,667 (GRCm39)	M24V	probably benign	Het
Prkca	A	G	11: 107,874,848 (GRCm39)	Y365H	probably damaging	Het
Ptpre	C	T	7: 135,255,744 (GRCm39)	R155*	probably null	Het
Ryr2	T	A	13: 11,684,873 (GRCm39)	N3023Y	probably damaging	Het
S100a7a	A	G	3: 90,562,822 (GRCm39)	D3G	probably benign	Het
Scn2a	T	C	2: 65,594,277 (GRCm39)	F1709L	probably damaging	Het
Slc15a2	T	C	16: 36,602,660 (GRCm39)	E67G	probably damaging	Het
Slc25a22	A	G	7: 141,011,655 (GRCm39)	L195P	probably damaging	Het
Sp140	TTTTTTTTTTTTT	TTTTTTTTTTTTTTTTTT	1: 85,572,290 (GRCm39)		probably benign	Het
Stim1	T	A	7: 102,084,741 (GRCm39)	H564Q	possibly damaging	Het
Sulf2	C	T	2: 165,917,448 (GRCm39)	W855*	probably null	Het
Tenm3	T	C	8: 49,127,588 (GRCm39)	N30S	probably benign	Het
Trim59	T	C	3: 68,944,197 (GRCm39)	D381G	probably benign	Het
Ttc21b	T	C	2: 66,066,670 (GRCm39)	T328A	probably benign	Het
Ttc6	C	G	12: 57,623,125 (GRCm39)	Q175E	probably benign	Het
Vmn2r44	T	C	7: 8,370,941 (GRCm39)	I702V	probably damaging	Het
Zfp768	A	T	7: 126,943,959 (GRCm39)	F59L	probably damaging	Het

Other mutations in Dnah2

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00087:Dnah2	APN	11	69,383,498 (GRCm39)	missense	possibly damaging	0.93
IGL00418:Dnah2	APN	11	69,385,892 (GRCm39)	splice site	probably benign
IGL00772:Dnah2	APN	11	69,342,083 (GRCm39)	missense	probably damaging	0.97
IGL00819:Dnah2	APN	11	69,364,176 (GRCm39)	critical splice donor site	probably null
IGL00827:Dnah2	APN	11	69,339,283 (GRCm39)	missense	probably damaging	1.00
IGL01060:Dnah2	APN	11	69,368,918 (GRCm39)	missense	possibly damaging	0.86
IGL01340:Dnah2	APN	11	69,384,010 (GRCm39)	missense	probably damaging	0.99
IGL01349:Dnah2	APN	11	69,366,432 (GRCm39)	missense	probably damaging	0.99
IGL01413:Dnah2	APN	11	69,323,790 (GRCm39)	missense	probably damaging	0.99
IGL01451:Dnah2	APN	11	69,365,017 (GRCm39)	splice site	probably benign
IGL01480:Dnah2	APN	11	69,349,197 (GRCm39)	missense	possibly damaging	0.91
IGL01537:Dnah2	APN	11	69,406,906 (GRCm39)	missense	probably benign	0.17
IGL01592:Dnah2	APN	11	69,321,913 (GRCm39)	missense	probably benign	0.14
IGL01612:Dnah2	APN	11	69,355,889 (GRCm39)	splice site	probably benign
IGL01667:Dnah2	APN	11	69,435,221 (GRCm39)	missense	probably benign
IGL01667:Dnah2	APN	11	69,411,767 (GRCm39)	missense	probably damaging	0.98
IGL01691:Dnah2	APN	11	69,430,269 (GRCm39)	missense	probably benign
IGL02019:Dnah2	APN	11	69,365,111 (GRCm39)	missense	probably damaging	1.00
IGL02039:Dnah2	APN	11	69,390,038 (GRCm39)	missense	probably damaging	1.00
IGL02076:Dnah2	APN	11	69,313,385 (GRCm39)	missense	probably damaging	0.99
IGL02085:Dnah2	APN	11	69,349,011 (GRCm39)	missense	probably benign	0.07
IGL02158:Dnah2	APN	11	69,348,949 (GRCm39)	missense	probably benign
IGL02381:Dnah2	APN	11	69,337,118 (GRCm39)	missense	probably benign	0.25
IGL02681:Dnah2	APN	11	69,343,759 (GRCm39)	missense	probably benign	0.40
IGL02957:Dnah2	APN	11	69,339,333 (GRCm39)	missense	possibly damaging	0.96
IGL02961:Dnah2	APN	11	69,409,240 (GRCm39)	missense	probably damaging	1.00
IGL02969:Dnah2	APN	11	69,412,013 (GRCm39)	missense	possibly damaging	0.80
IGL03117:Dnah2	APN	11	69,327,117 (GRCm39)	splice site	probably benign
IGL03120:Dnah2	APN	11	69,312,674 (GRCm39)	missense	probably damaging	1.00
IGL03183:Dnah2	APN	11	69,349,314 (GRCm39)	missense	possibly damaging	0.94
IGL03197:Dnah2	APN	11	69,350,089 (GRCm39)	missense	probably damaging	1.00
IGL03263:Dnah2	APN	11	69,420,207 (GRCm39)	critical splice donor site	probably null
IGL03333:Dnah2	APN	11	69,385,949 (GRCm39)	missense	probably damaging	1.00
IGL03338:Dnah2	APN	11	69,387,403 (GRCm39)	missense	probably benign	0.13
argyrios	UTSW	11	69,407,416 (GRCm39)	missense	possibly damaging	0.47
Aureus	UTSW	11	69,320,174 (GRCm39)	missense	probably damaging	1.00
platinum	UTSW	11	69,348,868 (GRCm39)	missense	probably damaging	0.96
R0334_dnah2_144	UTSW	11	69,327,662 (GRCm39)	missense	probably damaging	1.00
R2150_dnah2_212	UTSW	11	69,406,587 (GRCm39)	missense	probably benign	0.14
BB005:Dnah2	UTSW	11	69,321,661 (GRCm39)	missense	probably damaging	0.98
BB015:Dnah2	UTSW	11	69,321,661 (GRCm39)	missense	probably damaging	0.98
E0370:Dnah2	UTSW	11	69,406,441 (GRCm39)	splice site	probably null
P0026:Dnah2	UTSW	11	69,355,773 (GRCm39)	missense	probably damaging	1.00
R0133:Dnah2	UTSW	11	69,311,835 (GRCm39)	missense	probably damaging	1.00
R0190:Dnah2	UTSW	11	69,326,075 (GRCm39)	missense	probably damaging	1.00
R0334:Dnah2	UTSW	11	69,327,662 (GRCm39)	missense	probably damaging	1.00
R0359:Dnah2	UTSW	11	69,420,357 (GRCm39)	missense	probably benign	0.00
R0386:Dnah2	UTSW	11	69,338,687 (GRCm39)	missense	probably damaging	1.00
R0414:Dnah2	UTSW	11	69,390,064 (GRCm39)	missense	probably benign	0.26
R0427:Dnah2	UTSW	11	69,343,705 (GRCm39)	missense	probably damaging	0.99
R0433:Dnah2	UTSW	11	69,350,114 (GRCm39)	missense	probably damaging	1.00
R0442:Dnah2	UTSW	11	69,339,368 (GRCm39)	missense	probably damaging	1.00
R0462:Dnah2	UTSW	11	69,350,027 (GRCm39)	missense	probably damaging	1.00
R0463:Dnah2	UTSW	11	69,313,952 (GRCm39)	missense	probably damaging	1.00
R0611:Dnah2	UTSW	11	69,390,020 (GRCm39)	missense	probably damaging	1.00
R0626:Dnah2	UTSW	11	69,368,509 (GRCm39)	missense	probably benign	0.07
R0924:Dnah2	UTSW	11	69,312,134 (GRCm39)	missense	probably damaging	1.00
R0968:Dnah2	UTSW	11	69,339,345 (GRCm39)	missense	possibly damaging	0.67
R1066:Dnah2	UTSW	11	69,338,645 (GRCm39)	missense	probably damaging	1.00
R1183:Dnah2	UTSW	11	69,337,474 (GRCm39)	missense	possibly damaging	0.95
R1184:Dnah2	UTSW	11	69,390,016 (GRCm39)	missense	probably damaging	1.00
R1186:Dnah2	UTSW	11	69,406,526 (GRCm39)	missense	probably damaging	0.99
R1453:Dnah2	UTSW	11	69,341,876 (GRCm39)	missense	probably damaging	0.99
R1498:Dnah2	UTSW	11	69,411,493 (GRCm39)	splice site	probably null
R1538:Dnah2	UTSW	11	69,368,028 (GRCm39)	missense	probably benign	0.17
R1574:Dnah2	UTSW	11	69,405,514 (GRCm39)	missense	probably benign	0.26
R1574:Dnah2	UTSW	11	69,405,514 (GRCm39)	missense	probably benign	0.26
R1590:Dnah2	UTSW	11	69,412,024 (GRCm39)	missense	probably benign	0.00
R1590:Dnah2	UTSW	11	69,313,580 (GRCm39)	critical splice donor site	probably null
R1655:Dnah2	UTSW	11	69,364,680 (GRCm39)	missense	probably damaging	1.00
R1695:Dnah2	UTSW	11	69,405,517 (GRCm39)	missense	possibly damaging	0.74
R1726:Dnah2	UTSW	11	69,388,715 (GRCm39)	missense	probably damaging	1.00
R1764:Dnah2	UTSW	11	69,314,369 (GRCm39)	missense	probably damaging	1.00
R1815:Dnah2	UTSW	11	69,366,400 (GRCm39)	missense	probably damaging	1.00
R1822:Dnah2	UTSW	11	69,405,630 (GRCm39)	missense	probably damaging	1.00
R1859:Dnah2	UTSW	11	69,328,712 (GRCm39)	missense	probably damaging	0.99
R1911:Dnah2	UTSW	11	69,406,578 (GRCm39)	missense	possibly damaging	0.64
R1913:Dnah2	UTSW	11	69,355,756 (GRCm39)	missense	probably damaging	1.00
R1981:Dnah2	UTSW	11	69,365,151 (GRCm39)	missense	probably damaging	1.00
R2010:Dnah2	UTSW	11	69,349,184 (GRCm39)	critical splice donor site	probably null
R2016:Dnah2	UTSW	11	69,327,896 (GRCm39)	missense	probably damaging	0.97
R2017:Dnah2	UTSW	11	69,327,896 (GRCm39)	missense	probably damaging	0.97
R2044:Dnah2	UTSW	11	69,415,066 (GRCm39)	missense	probably benign	0.14
R2077:Dnah2	UTSW	11	69,387,432 (GRCm39)	missense	possibly damaging	0.73
R2096:Dnah2	UTSW	11	69,346,742 (GRCm39)	missense	probably damaging	0.98
R2099:Dnah2	UTSW	11	69,384,063 (GRCm39)	missense	probably damaging	1.00
R2127:Dnah2	UTSW	11	69,349,011 (GRCm39)	missense	probably benign	0.02
R2128:Dnah2	UTSW	11	69,349,011 (GRCm39)	missense	probably benign	0.02
R2146:Dnah2	UTSW	11	69,406,587 (GRCm39)	missense	probably benign	0.14
R2147:Dnah2	UTSW	11	69,406,587 (GRCm39)	missense	probably benign	0.14
R2150:Dnah2	UTSW	11	69,406,587 (GRCm39)	missense	probably benign	0.14
R2404:Dnah2	UTSW	11	69,328,047 (GRCm39)	missense	probably damaging	0.99
R2510:Dnah2	UTSW	11	69,415,032 (GRCm39)	nonsense	probably null
R2517:Dnah2	UTSW	11	69,407,470 (GRCm39)	missense	probably damaging	1.00
R3014:Dnah2	UTSW	11	69,321,304 (GRCm39)	missense	probably benign
R3741:Dnah2	UTSW	11	69,339,295 (GRCm39)	missense	probably damaging	1.00
R3814:Dnah2	UTSW	11	69,383,476 (GRCm39)	splice site	probably null
R3872:Dnah2	UTSW	11	69,320,174 (GRCm39)	missense	probably damaging	1.00
R3873:Dnah2	UTSW	11	69,320,174 (GRCm39)	missense	probably damaging	1.00
R3874:Dnah2	UTSW	11	69,320,174 (GRCm39)	missense	probably damaging	1.00
R3875:Dnah2	UTSW	11	69,320,174 (GRCm39)	missense	probably damaging	1.00
R3881:Dnah2	UTSW	11	69,342,173 (GRCm39)	missense	possibly damaging	0.94
R3953:Dnah2	UTSW	11	69,344,929 (GRCm39)	missense	probably damaging	1.00
R3956:Dnah2	UTSW	11	69,374,847 (GRCm39)	missense	probably benign	0.00
R4501:Dnah2	UTSW	11	69,368,485 (GRCm39)	missense	probably benign
R4515:Dnah2	UTSW	11	69,356,457 (GRCm39)	missense	possibly damaging	0.61
R4612:Dnah2	UTSW	11	69,374,193 (GRCm39)	missense	possibly damaging	0.93
R4625:Dnah2	UTSW	11	69,354,487 (GRCm39)	missense	probably damaging	1.00
R4627:Dnah2	UTSW	11	69,356,202 (GRCm39)	missense	probably damaging	1.00
R4642:Dnah2	UTSW	11	69,387,385 (GRCm39)	missense	probably benign	0.00
R4683:Dnah2	UTSW	11	69,349,768 (GRCm39)	missense	probably damaging	1.00
R4698:Dnah2	UTSW	11	69,389,358 (GRCm39)	missense	probably damaging	1.00
R4710:Dnah2	UTSW	11	69,368,903 (GRCm39)	missense	probably damaging	1.00
R4712:Dnah2	UTSW	11	69,407,416 (GRCm39)	missense	possibly damaging	0.47
R4713:Dnah2	UTSW	11	69,367,514 (GRCm39)	missense	probably damaging	1.00
R4717:Dnah2	UTSW	11	69,320,183 (GRCm39)	missense	probably benign	0.00
R4740:Dnah2	UTSW	11	69,348,868 (GRCm39)	missense	probably damaging	0.96
R4780:Dnah2	UTSW	11	69,364,697 (GRCm39)	missense	probably damaging	0.97
R4825:Dnah2	UTSW	11	69,314,031 (GRCm39)	missense	probably damaging	1.00
R4864:Dnah2	UTSW	11	69,313,416 (GRCm39)	missense	probably damaging	0.98
R4868:Dnah2	UTSW	11	69,354,474 (GRCm39)	missense	probably damaging	1.00
R4879:Dnah2	UTSW	11	69,367,517 (GRCm39)	missense	probably damaging	1.00
R4908:Dnah2	UTSW	11	69,411,973 (GRCm39)	missense	probably benign	0.00
R4911:Dnah2	UTSW	11	69,389,930 (GRCm39)	critical splice donor site	probably null
R4954:Dnah2	UTSW	11	69,430,322 (GRCm39)	missense	possibly damaging	0.61
R4962:Dnah2	UTSW	11	69,346,799 (GRCm39)	nonsense	probably null
R5015:Dnah2	UTSW	11	69,388,708 (GRCm39)	missense	possibly damaging	0.89
R5049:Dnah2	UTSW	11	69,338,992 (GRCm39)	missense	probably damaging	1.00
R5055:Dnah2	UTSW	11	69,411,599 (GRCm39)	missense	possibly damaging	0.67
R5153:Dnah2	UTSW	11	69,411,759 (GRCm39)	missense	possibly damaging	0.84
R5155:Dnah2	UTSW	11	69,313,362 (GRCm39)	missense	probably damaging	1.00
R5186:Dnah2	UTSW	11	69,326,710 (GRCm39)	missense	probably damaging	1.00
R5187:Dnah2	UTSW	11	69,349,746 (GRCm39)	missense	probably benign	0.15
R5208:Dnah2	UTSW	11	69,349,746 (GRCm39)	missense	probably benign	0.15
R5252:Dnah2	UTSW	11	69,420,295 (GRCm39)	missense	probably damaging	0.98
R5296:Dnah2	UTSW	11	69,349,746 (GRCm39)	missense	probably benign	0.15
R5298:Dnah2	UTSW	11	69,349,746 (GRCm39)	missense	probably benign	0.15
R5299:Dnah2	UTSW	11	69,349,746 (GRCm39)	missense	probably benign	0.15
R5301:Dnah2	UTSW	11	69,349,746 (GRCm39)	missense	probably benign	0.15
R5324:Dnah2	UTSW	11	69,348,819 (GRCm39)	missense	probably benign	0.07
R5350:Dnah2	UTSW	11	69,406,862 (GRCm39)	missense	possibly damaging	0.48
R5377:Dnah2	UTSW	11	69,312,674 (GRCm39)	missense	probably damaging	1.00
R5393:Dnah2	UTSW	11	69,391,683 (GRCm39)	missense	probably benign
R5421:Dnah2	UTSW	11	69,326,462 (GRCm39)	missense	probably damaging	1.00
R5452:Dnah2	UTSW	11	69,415,209 (GRCm39)	missense	probably damaging	1.00
R5461:Dnah2	UTSW	11	69,364,177 (GRCm39)	critical splice donor site	probably null
R5474:Dnah2	UTSW	11	69,349,746 (GRCm39)	missense	probably benign	0.15
R5476:Dnah2	UTSW	11	69,349,746 (GRCm39)	missense	probably benign	0.15
R5477:Dnah2	UTSW	11	69,349,746 (GRCm39)	missense	probably benign	0.15
R5510:Dnah2	UTSW	11	69,349,746 (GRCm39)	missense	probably benign	0.15
R5527:Dnah2	UTSW	11	69,328,014 (GRCm39)	nonsense	probably null
R5566:Dnah2	UTSW	11	69,407,395 (GRCm39)	nonsense	probably null
R5587:Dnah2	UTSW	11	69,328,068 (GRCm39)	missense	probably damaging	1.00
R5628:Dnah2	UTSW	11	69,349,746 (GRCm39)	missense	probably benign	0.15
R5688:Dnah2	UTSW	11	69,349,746 (GRCm39)	missense	probably benign	0.15
R5690:Dnah2	UTSW	11	69,382,370 (GRCm39)	missense	probably benign	0.15
R5711:Dnah2	UTSW	11	69,326,216 (GRCm39)	missense	probably damaging	1.00
R5735:Dnah2	UTSW	11	69,321,643 (GRCm39)	missense	possibly damaging	0.93
R5826:Dnah2	UTSW	11	69,349,746 (GRCm39)	missense	probably benign	0.15
R5913:Dnah2	UTSW	11	69,339,256 (GRCm39)	missense	probably damaging	1.00
R5914:Dnah2	UTSW	11	69,349,746 (GRCm39)	missense	probably benign	0.15
R5960:Dnah2	UTSW	11	69,349,746 (GRCm39)	missense	probably benign	0.15
R5961:Dnah2	UTSW	11	69,349,746 (GRCm39)	missense	probably benign	0.15
R5961:Dnah2	UTSW	11	69,321,974 (GRCm39)	missense	probably damaging	1.00
R5977:Dnah2	UTSW	11	69,411,707 (GRCm39)	missense	possibly damaging	0.79
R6020:Dnah2	UTSW	11	69,391,665 (GRCm39)	missense	probably benign
R6036:Dnah2	UTSW	11	69,349,746 (GRCm39)	missense	probably benign	0.15
R6036:Dnah2	UTSW	11	69,349,746 (GRCm39)	missense	probably benign	0.15
R6050:Dnah2	UTSW	11	69,349,746 (GRCm39)	missense	probably benign	0.15
R6086:Dnah2	UTSW	11	69,406,834 (GRCm39)	missense	probably benign	0.30
R6115:Dnah2	UTSW	11	69,337,475 (GRCm39)	missense	probably damaging	1.00
R6123:Dnah2	UTSW	11	69,409,185 (GRCm39)	missense	probably benign	0.29
R6159:Dnah2	UTSW	11	69,349,746 (GRCm39)	missense	probably benign	0.15
R6159:Dnah2	UTSW	11	69,349,368 (GRCm39)	missense	probably damaging	1.00
R6163:Dnah2	UTSW	11	69,411,729 (GRCm39)	nonsense	probably null
R6171:Dnah2	UTSW	11	69,313,868 (GRCm39)	missense	probably damaging	1.00
R6263:Dnah2	UTSW	11	69,348,238 (GRCm39)	missense	probably damaging	1.00
R6298:Dnah2	UTSW	11	69,382,467 (GRCm39)	missense	probably benign	0.25
R6352:Dnah2	UTSW	11	69,339,053 (GRCm39)	missense	probably damaging	1.00
R6399:Dnah2	UTSW	11	69,349,344 (GRCm39)	missense	probably damaging	0.98
R6466:Dnah2	UTSW	11	69,430,241 (GRCm39)	missense	probably benign
R6478:Dnah2	UTSW	11	69,406,836 (GRCm39)	missense	probably benign	0.01
R6516:Dnah2	UTSW	11	69,356,212 (GRCm39)	missense	probably benign	0.34
R6538:Dnah2	UTSW	11	69,328,023 (GRCm39)	missense	possibly damaging	0.87
R6802:Dnah2	UTSW	11	69,314,516 (GRCm39)	missense	probably damaging	1.00
R6861:Dnah2	UTSW	11	69,346,789 (GRCm39)	missense	possibly damaging	0.64
R6869:Dnah2	UTSW	11	69,320,297 (GRCm39)	missense	probably damaging	1.00
R6894:Dnah2	UTSW	11	69,375,086 (GRCm39)	missense	probably benign	0.12
R6935:Dnah2	UTSW	11	69,312,567 (GRCm39)	missense	probably damaging	1.00
R7017:Dnah2	UTSW	11	69,382,373 (GRCm39)	nonsense	probably null
R7073:Dnah2	UTSW	11	69,321,318 (GRCm39)	nonsense	probably null
R7111:Dnah2	UTSW	11	69,337,579 (GRCm39)	splice site	probably null
R7137:Dnah2	UTSW	11	69,382,381 (GRCm39)	missense	probably damaging	1.00
R7190:Dnah2	UTSW	11	69,439,923 (GRCm39)	splice site	probably null
R7214:Dnah2	UTSW	11	69,321,935 (GRCm39)	missense	probably damaging	1.00
R7227:Dnah2	UTSW	11	69,312,222 (GRCm39)	missense	probably damaging	0.99
R7238:Dnah2	UTSW	11	69,349,972 (GRCm39)	critical splice donor site	probably null
R7256:Dnah2	UTSW	11	69,321,920 (GRCm39)	missense	probably damaging	1.00
R7267:Dnah2	UTSW	11	69,391,643 (GRCm39)	missense	probably damaging	1.00
R7420:Dnah2	UTSW	11	69,369,623 (GRCm39)	missense	possibly damaging	0.94
R7421:Dnah2	UTSW	11	69,383,631 (GRCm39)	missense	probably benign	0.25
R7437:Dnah2	UTSW	11	69,389,453 (GRCm39)	missense	probably damaging	1.00
R7461:Dnah2	UTSW	11	69,439,816 (GRCm39)	critical splice donor site	probably null
R7473:Dnah2	UTSW	11	69,382,484 (GRCm39)	missense	probably damaging	0.99
R7528:Dnah2	UTSW	11	69,391,622 (GRCm39)	missense	probably damaging	0.99
R7613:Dnah2	UTSW	11	69,439,816 (GRCm39)	critical splice donor site	probably null
R7615:Dnah2	UTSW	11	69,326,130 (GRCm39)	missense	probably damaging	0.99
R7626:Dnah2	UTSW	11	69,389,511 (GRCm39)	missense	probably damaging	0.99
R7745:Dnah2	UTSW	11	69,342,144 (GRCm39)	nonsense	probably null
R7764:Dnah2	UTSW	11	69,348,984 (GRCm39)	missense	probably benign	0.29
R7793:Dnah2	UTSW	11	69,386,040 (GRCm39)	missense	probably benign	0.00
R7819:Dnah2	UTSW	11	69,407,419 (GRCm39)	missense	probably benign	0.01
R7881:Dnah2	UTSW	11	69,322,064 (GRCm39)	missense	probably damaging	1.00
R7900:Dnah2	UTSW	11	69,409,254 (GRCm39)	missense	probably damaging	1.00
R7916:Dnah2	UTSW	11	69,311,974 (GRCm39)	critical splice acceptor site	probably null
R7921:Dnah2	UTSW	11	69,411,660 (GRCm39)	missense	probably benign
R7928:Dnah2	UTSW	11	69,321,661 (GRCm39)	missense	probably damaging	0.98
R7937:Dnah2	UTSW	11	69,408,511 (GRCm39)	nonsense	probably null
R7995:Dnah2	UTSW	11	69,411,563 (GRCm39)	missense	possibly damaging	0.77
R8202:Dnah2	UTSW	11	69,369,649 (GRCm39)	missense	probably benign	0.00
R8208:Dnah2	UTSW	11	69,411,678 (GRCm39)	missense	probably benign	0.05
R8215:Dnah2	UTSW	11	69,326,193 (GRCm39)	missense	probably damaging	1.00
R8279:Dnah2	UTSW	11	69,366,399 (GRCm39)	missense	probably damaging	1.00
R8338:Dnah2	UTSW	11	69,378,122 (GRCm39)	missense	probably damaging	1.00
R8348:Dnah2	UTSW	11	69,320,273 (GRCm39)	missense	possibly damaging	0.95
R8405:Dnah2	UTSW	11	69,349,289 (GRCm39)	missense	probably damaging	1.00
R8407:Dnah2	UTSW	11	69,350,104 (GRCm39)	missense	probably benign	0.00
R8493:Dnah2	UTSW	11	69,343,804 (GRCm39)	missense	probably damaging	1.00
R8673:Dnah2	UTSW	11	69,405,523 (GRCm39)	missense	probably benign	0.23
R8725:Dnah2	UTSW	11	69,415,005 (GRCm39)	missense	probably damaging	1.00
R8727:Dnah2	UTSW	11	69,415,005 (GRCm39)	missense	probably damaging	1.00
R8730:Dnah2	UTSW	11	69,384,087 (GRCm39)	missense	possibly damaging	0.73
R8804:Dnah2	UTSW	11	69,356,511 (GRCm39)	missense	probably benign	0.01
R8876:Dnah2	UTSW	11	69,382,348 (GRCm39)	missense	probably damaging	1.00
R8894:Dnah2	UTSW	11	69,383,048 (GRCm39)	missense	probably benign	0.01
R8938:Dnah2	UTSW	11	69,328,754 (GRCm39)	missense	probably damaging	0.99
R9044:Dnah2	UTSW	11	69,420,247 (GRCm39)	missense	probably benign
R9085:Dnah2	UTSW	11	69,320,224 (GRCm39)	missense	possibly damaging	0.69
R9110:Dnah2	UTSW	11	69,435,208 (GRCm39)	missense	probably benign
R9156:Dnah2	UTSW	11	69,313,687 (GRCm39)	missense
R9251:Dnah2	UTSW	11	69,406,619 (GRCm39)	missense	probably damaging	1.00
R9258:Dnah2	UTSW	11	69,368,079 (GRCm39)	missense	probably damaging	1.00
R9279:Dnah2	UTSW	11	69,409,104 (GRCm39)	missense	probably benign	0.01
R9318:Dnah2	UTSW	11	69,375,155 (GRCm39)	missense	probably benign	0.07
R9321:Dnah2	UTSW	11	69,338,939 (GRCm39)	critical splice donor site	probably null
R9350:Dnah2	UTSW	11	69,384,073 (GRCm39)	missense	probably benign	0.10
R9358:Dnah2	UTSW	11	69,406,592 (GRCm39)	missense	probably damaging	0.99
R9417:Dnah2	UTSW	11	69,326,990 (GRCm39)	missense	probably damaging	1.00
R9420:Dnah2	UTSW	11	69,368,942 (GRCm39)	missense	probably benign	0.09
R9438:Dnah2	UTSW	11	69,364,220 (GRCm39)	missense	probably damaging	1.00
R9469:Dnah2	UTSW	11	69,321,896 (GRCm39)	missense	probably damaging	1.00
R9487:Dnah2	UTSW	11	69,406,617 (GRCm39)	missense	possibly damaging	0.47
R9495:Dnah2	UTSW	11	69,345,208 (GRCm39)	missense	possibly damaging	0.89
R9579:Dnah2	UTSW	11	69,368,041 (GRCm39)	missense	probably damaging	1.00
R9608:Dnah2	UTSW	11	69,344,888 (GRCm39)	missense	probably null	1.00
R9651:Dnah2	UTSW	11	69,341,824 (GRCm39)	critical splice donor site	probably null
R9662:Dnah2	UTSW	11	69,343,763 (GRCm39)	missense	probably benign
RF004:Dnah2	UTSW	11	69,328,013 (GRCm39)	missense	probably benign	0.24
U24488:Dnah2	UTSW	11	69,374,648 (GRCm39)	missense	probably damaging	0.99
X0021:Dnah2	UTSW	11	69,339,388 (GRCm39)	missense	possibly damaging	0.81
Z1088:Dnah2	UTSW	11	69,321,619 (GRCm39)	missense	probably damaging	1.00
Z1176:Dnah2	UTSW	11	69,312,647 (GRCm39)	missense	possibly damaging	0.46
Z1176:Dnah2	UTSW	11	69,407,349 (GRCm39)	missense	probably damaging	1.00
Z1176:Dnah2	UTSW	11	69,407,307 (GRCm39)	missense	probably damaging	1.00
Z1176:Dnah2	UTSW	11	69,389,493 (GRCm39)	missense	probably benign	0.12
Z1176:Dnah2	UTSW	11	69,377,880 (GRCm39)	missense	possibly damaging	0.46
Z1176:Dnah2	UTSW	11	69,341,946 (GRCm39)	missense	probably benign
Z1177:Dnah2	UTSW	11	69,435,383 (GRCm39)	critical splice acceptor site	probably null
Z1177:Dnah2	UTSW	11	69,354,279 (GRCm39)	missense	possibly damaging	0.63

Predicted Primers

PCR Primer
(F):5'- GCTCCTTCCGAACCACAATG -3'
(R):5'- AGTGAAGCAGGCTGAGTCAC -3'

Sequencing Primer
(F):5'- CCCTGAGGAGGTCAAGACTC -3'
(R):5'- TCACATCTCGGGCCTAGGTATAAG -3'

Posted On

2019-05-15