Mutagenetix > Incidental Mutation

Incidental Mutation 'R7133:Smg1'

552825

Institutional Source

Beutler Lab

Gene Symbol

Smg1

Ensembl Gene

ENSMUSG00000030655

Gene Name

SMG1 homolog, phosphatidylinositol 3-kinase-related kinase (C. elegans)

Synonyms

2610207I05Rik, 5430435M13Rik, C130002K18Rik

MMRRC Submission

045218-MU

Accession Numbers

Essential gene?

Essential (E-score: 1.000) question?

Stock #

R7133 (G1)

Quality Score

225.009

Status

Validated

Chromosome

Chromosomal Location

118131308-118243670 bp(-) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

C to T at 118152908 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Cysteine to Tyrosine at position 2698 (C2698Y)

Ref Sequence

ENSEMBL: ENSMUSP00000032891 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000032891]

AlphaFold

no structure available at present

Predicted Effect

unknown
Transcript: ENSMUST00000032891
AA Change: C2698Y

SMART Domains

Protein: ENSMUSP00000032891
Gene: ENSMUSG00000030655
AA Change: C2698Y

Domain	Start	End	E-Value	Type
low complexity region	42	55	N/A	INTRINSIC
SCOP:d1gw5a_	147	621	7e-7	SMART
Pfam:SMG1	629	1240	9.8e-249	PFAM
low complexity region	1540	1551	N/A	INTRINSIC
SCOP:d1gw5a_	1680	1942	8e-3	SMART
low complexity region	2125	2141	N/A	INTRINSIC
PI3Kc	2149	2493	7.93e-50	SMART
low complexity region	2759	2770	N/A	INTRINSIC
low complexity region	3425	3442	N/A	INTRINSIC
FATC	3626	3658	8.66e-12	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000179331

SMART Domains

Protein: ENSMUSP00000137592
Gene: ENSMUSG00000030655

Domain	Start	End	E-Value	Type
low complexity region	18	31	N/A	INTRINSIC
SCOP:d1gw5a_	71	545	1e-6	SMART
low complexity region	602	612	N/A	INTRINSIC
low complexity region	631	646	N/A	INTRINSIC
low complexity region	698	718	N/A	INTRINSIC
low complexity region	898	915	N/A	INTRINSIC
low complexity region	1135	1147	N/A	INTRINSIC
low complexity region	1464	1475	N/A	INTRINSIC
low complexity region	2049	2065	N/A	INTRINSIC
PI3Kc	2073	2417	7.93e-50	SMART
low complexity region	2683	2694	N/A	INTRINSIC
low complexity region	3349	3366	N/A	INTRINSIC
FATC	3550	3582	8.66e-12	SMART

Coding Region Coverage

1x: 100.0%
3x: 100.0%
10x: 99.7%
20x: 99.0%

Validation Efficiency

98% (91/93)

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a protein involved in nonsense-mediated mRNA decay (NMD) as part of the mRNA surveillance complex. The protein has kinase activity and is thought to function in NMD by phosphorylating the regulator of nonsense transcripts 1 protein. Alternatively spliced transcript variants have been described, but their full-length nature has yet to be determined. [provided by RefSeq, Mar 2013]
PHENOTYPE: Mice homozygous for a gene trap allele exhibit early embryonic lethality. Mice heteroygous for a gene trap allele exhibit abnormal tooth development, chronic inflammation, increased body weight, increased incidence of tumor formation and premature death. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 91 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
2610008E11Rik	T	G	10: 79,066,640 (GRCm38)	K614T	probably benign	Het
2610008E11Rik	T	A	10: 79,066,639 (GRCm38)	K614N	probably benign	Het
Ahsa1	T	A	12: 87,270,342 (GRCm38)	S120R	probably benign	Het
Anapc16	G	A	10: 59,996,480 (GRCm38)	T37I	possibly damaging	Het
Arid2	C	A	15: 96,378,875 (GRCm38)	P1606H	probably damaging	Het
Ash1l	TATCTCCTTTTCCAAAAA	TA	3: 88,983,457 (GRCm38)		probably null	Het
Asic1	T	A	15: 99,672,087 (GRCm38)	N96K	probably damaging	Het
Asph	A	T	4: 9,484,575 (GRCm38)	D582E	probably benign	Het
Astn1	A	G	1: 158,572,987 (GRCm38)	D528G	probably damaging	Het
Atp9b	A	G	18: 80,909,656 (GRCm38)	V164A		Het
Cbx6	C	T	15: 79,828,665 (GRCm38)	G187D	possibly damaging	Het
Cct7	A	G	6: 85,466,645 (GRCm38)	T332A	probably benign	Het
Clca4a	A	T	3: 144,961,890 (GRCm38)	L440*	probably null	Het
Crybg2	A	T	4: 134,065,443 (GRCm38)	I130F	probably benign	Het
Crybg3	T	C	16: 59,536,804 (GRCm38)	E798G	probably damaging	Het
Ctnnd2	A	G	15: 30,480,849 (GRCm38)	E81G	possibly damaging	Het
Cwc22	C	T	2: 77,929,478 (GRCm38)	R75H	possibly damaging	Het
Cym	T	G	3: 107,214,214 (GRCm38)	D254A	probably damaging	Het
Dcaf11	T	A	14: 55,568,926 (GRCm38)		probably null	Het
Dctn1	A	T	6: 83,180,044 (GRCm38)		probably null	Het
Dennd5a	C	T	7: 109,896,242 (GRCm38)		probably null	Het
Dmpk	T	A	7: 19,087,307 (GRCm38)	C217S	probably damaging	Het
Dnah1	C	A	14: 31,286,076 (GRCm38)	V2125L	probably benign	Het
Exoc4	G	A	6: 33,438,473 (GRCm38)	A427T	probably benign	Het
Farp2	G	T	1: 93,621,234 (GRCm38)	V1021F	probably damaging	Het
Flg2	T	C	3: 93,219,762 (GRCm38)	S1994P	unknown	Het
Fmnl1	T	C	11: 103,181,784 (GRCm38)		probably null	Het
Frem2	T	A	3: 53,572,339 (GRCm38)	I1978F	possibly damaging	Het
Gan	T	A	8: 117,187,230 (GRCm38)	C122*	probably null	Het
Gpr25	T	A	1: 136,260,821 (GRCm38)	Y18F	probably damaging	Het
Hoxa7	C	T	6: 52,215,740 (GRCm38)	E223K	probably benign	Het
Hypk	A	G	2: 121,453,480 (GRCm38)		probably null	Het
Ibsp	A	T	5: 104,302,306 (GRCm38)	K27*	probably null	Het
Ighv6-5	T	A	12: 114,416,775 (GRCm38)	T41S	probably benign	Het
Ighv9-4	T	C	12: 114,300,137 (GRCm38)	M59V	probably benign	Het
Il17rb	T	C	14: 29,996,871 (GRCm38)	D418G	probably damaging	Het
Ints5	T	A	19: 8,895,559 (GRCm38)	V294E	probably damaging	Het
Irx6	G	A	8: 92,678,413 (GRCm38)	C303Y	probably damaging	Het
Itih3	T	A	14: 30,917,698 (GRCm38)	I389F	probably damaging	Het
Lama1	C	T	17: 67,782,146 (GRCm38)	T1604I		Het
Lama3	C	A	18: 12,539,786 (GRCm38)	Q873K	probably benign	Het
Lhx1	T	G	11: 84,519,920 (GRCm38)	S284R	probably benign	Het
Lrba	T	A	3: 86,394,931 (GRCm38)		probably null	Het
Lrg1	C	T	17: 56,120,592 (GRCm38)	G127R	possibly damaging	Het
Macir	G	A	1: 97,645,920 (GRCm38)	P140L	probably benign	Het
Mapre1	T	A	2: 153,764,963 (GRCm38)	L205H	probably benign	Het
Meltf	A	G	16: 31,892,799 (GRCm38)	N581S	probably damaging	Het
Mgat5	A	C	1: 127,365,189 (GRCm38)	M149L	probably benign	Het
Myh1	A	G	11: 67,202,586 (GRCm38)	T168A	probably benign	Het
Naalad2	C	T	9: 18,327,377 (GRCm38)	V681I	probably benign	Het
Or51e2	A	G	7: 102,742,317 (GRCm38)	S229P	probably damaging	Het
Or52r1c	T	A	7: 103,085,998 (GRCm38)	L155Q	probably damaging	Het
Pcnx2	T	C	8: 125,801,504 (GRCm38)	T1326A	probably benign	Het
Peg3	A	T	7: 6,708,945 (GRCm38)	C1093S	probably damaging	Het
Pidd1	T	C	7: 141,439,900 (GRCm38)	S650G	probably benign	Het
Pik3c2b	T	C	1: 133,090,234 (GRCm38)	S945P	possibly damaging	Het
Plec	T	C	15: 76,176,027 (GRCm38)	T3237A	possibly damaging	Het
Prpf3	A	T	3: 95,833,740 (GRCm38)		probably null	Het
Prpf4b	C	A	13: 34,901,494 (GRCm38)	H974Q	probably benign	Het
Ptpn3	T	C	4: 57,225,863 (GRCm38)	T451A	probably benign	Het
Ptprs	A	G	17: 56,417,429 (GRCm38)	Y1577H	probably damaging	Het
Rgr	C	T	14: 37,048,925 (GRCm38)	M1I	probably null	Het
Rxrg	A	T	1: 167,631,109 (GRCm38)	N257I	probably benign	Het
Sbno2	T	C	10: 80,086,312 (GRCm38)	D9G	probably damaging	Het
Scd1	T	C	19: 44,406,595 (GRCm38)	K64E	probably damaging	Het
Serpinb1a	T	A	13: 32,850,325 (GRCm38)	I28F	possibly damaging	Het
Sfmbt2	A	T	2: 10,402,007 (GRCm38)	E39V	probably damaging	Het
Slc29a1	A	G	17: 45,589,971 (GRCm38)	M89T	possibly damaging	Het
Slco4a1	T	A	2: 180,472,063 (GRCm38)	V431E	possibly damaging	Het
Sptlc2	C	T	12: 87,350,377 (GRCm38)	D212N	probably benign	Het
St6galnac1	T	C	11: 116,767,073 (GRCm38)	T334A	possibly damaging	Het
Stim2	A	T	5: 53,998,921 (GRCm38)	D13V	possibly damaging	Het
Syne1	A	G	10: 5,231,592 (GRCm38)	W4248R	probably damaging	Het
Tanc1	T	C	2: 59,797,609 (GRCm38)	Y584H	probably benign	Het
Thoc6	C	A	17: 23,673,660 (GRCm38)		probably null	Het
Trim30a	T	A	7: 104,429,326 (GRCm38)	N181I	possibly damaging	Het
Trip11	T	A	12: 101,884,070 (GRCm38)	Q1245L	probably damaging	Het
Tshz3	A	G	7: 36,770,569 (GRCm38)	D661G	probably benign	Het
Ttll8	C	A	15: 88,915,427 (GRCm38)	V604L	probably damaging	Het
Ubtfl1	A	G	9: 18,409,635 (GRCm38)	D153G	probably damaging	Het
Ufsp2	C	A	8: 45,983,624 (GRCm38)	N137K	probably benign	Het
Ugt2a3	A	G	5: 87,325,534 (GRCm38)	I508T	possibly damaging	Het
Uso1	G	A	5: 92,158,465 (GRCm38)	E94K	probably benign	Het
Usp54	A	G	14: 20,561,242 (GRCm38)	S1169P	probably benign	Het
Vmn1r235	C	T	17: 21,262,030 (GRCm38)	P206S	probably benign	Het
Vmn1r69	T	C	7: 10,581,068 (GRCm38)		probably benign	Het
Zfp263	T	A	16: 3,749,391 (GRCm38)	C523*	probably null	Het
Zfp799	G	T	17: 32,820,236 (GRCm38)	T352K	probably benign	Het
Zfr	T	A	15: 12,180,638 (GRCm38)	V951E	probably damaging	Het
Zfyve26	T	C	12: 79,284,152 (GRCm38)	D431G	probably benign	Het
Zswim9	C	A	7: 13,259,737 (GRCm38)	A831S	probably damaging	Het

Other mutations in Smg1

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00272:Smg1	APN	7	118,198,271 (GRCm38)	utr 3 prime	probably benign
IGL00481:Smg1	APN	7	118,210,794 (GRCm38)	missense	possibly damaging	0.67
IGL00503:Smg1	APN	7	118,185,483 (GRCm38)	utr 3 prime	probably benign
IGL00927:Smg1	APN	7	118,140,632 (GRCm38)	missense	probably damaging	1.00
IGL01333:Smg1	APN	7	118,163,378 (GRCm38)	splice site	probably benign
IGL01344:Smg1	APN	7	118,190,836 (GRCm38)	utr 3 prime	probably benign
IGL01397:Smg1	APN	7	118,163,221 (GRCm38)	utr 3 prime	probably benign
IGL01403:Smg1	APN	7	118,158,132 (GRCm38)	utr 3 prime	probably benign
IGL01573:Smg1	APN	7	118,167,962 (GRCm38)	utr 3 prime	probably benign
IGL01872:Smg1	APN	7	118,148,944 (GRCm38)	utr 3 prime	probably benign
IGL02010:Smg1	APN	7	118,186,146 (GRCm38)	utr 3 prime	probably benign
IGL02158:Smg1	APN	7	118,212,946 (GRCm38)	missense	possibly damaging	0.77
IGL02268:Smg1	APN	7	118,182,541 (GRCm38)	missense	probably benign	0.19
IGL02314:Smg1	APN	7	118,154,709 (GRCm38)	utr 3 prime	probably benign
IGL02552:Smg1	APN	7	118,195,894 (GRCm38)	utr 3 prime	probably benign
IGL02577:Smg1	APN	7	118,203,122 (GRCm38)	missense	probably damaging	0.99
IGL02859:Smg1	APN	7	118,148,933 (GRCm38)	utr 3 prime	probably benign
IGL02890:Smg1	APN	7	118,185,501 (GRCm38)	utr 3 prime	probably benign
IGL02892:Smg1	APN	7	118,167,955 (GRCm38)	utr 3 prime	probably benign
IGL03119:Smg1	APN	7	118,195,113 (GRCm38)	utr 3 prime	probably benign
IGL03123:Smg1	APN	7	118,157,181 (GRCm38)	utr 3 prime	probably benign
IGL03128:Smg1	APN	7	118,203,059 (GRCm38)	missense	probably benign	0.03
IGL03184:Smg1	APN	7	118,180,380 (GRCm38)	missense	possibly damaging	0.86
PIT4508001:Smg1	UTSW	7	118,185,541 (GRCm38)	missense	unknown
R0010:Smg1	UTSW	7	118,171,859 (GRCm38)	utr 3 prime	probably benign
R0010:Smg1	UTSW	7	118,171,859 (GRCm38)	utr 3 prime	probably benign
R0025:Smg1	UTSW	7	118,212,443 (GRCm38)	missense	possibly damaging	0.92
R0025:Smg1	UTSW	7	118,212,443 (GRCm38)	missense	possibly damaging	0.92
R0098:Smg1	UTSW	7	118,145,467 (GRCm38)	missense	probably benign	0.02
R0139:Smg1	UTSW	7	118,152,675 (GRCm38)	critical splice donor site	probably null
R0371:Smg1	UTSW	7	118,168,300 (GRCm38)	utr 3 prime	probably benign
R0415:Smg1	UTSW	7	118,182,468 (GRCm38)	missense	probably benign	0.34
R0416:Smg1	UTSW	7	118,184,461 (GRCm38)	splice site	probably benign
R0423:Smg1	UTSW	7	118,176,880 (GRCm38)	missense	possibly damaging	0.53
R0600:Smg1	UTSW	7	118,160,383 (GRCm38)	utr 3 prime	probably benign
R0626:Smg1	UTSW	7	118,182,383 (GRCm38)	missense	possibly damaging	0.82
R0627:Smg1	UTSW	7	118,167,861 (GRCm38)	utr 3 prime	probably benign
R0727:Smg1	UTSW	7	118,166,422 (GRCm38)	utr 3 prime	probably benign
R0729:Smg1	UTSW	7	118,146,289 (GRCm38)	utr 3 prime	probably benign
R0841:Smg1	UTSW	7	118,143,301 (GRCm38)	missense	possibly damaging	0.96
R1114:Smg1	UTSW	7	118,159,790 (GRCm38)	utr 3 prime	probably benign
R1256:Smg1	UTSW	7	118,203,087 (GRCm38)	missense	probably damaging	1.00
R1298:Smg1	UTSW	7	118,168,211 (GRCm38)	utr 3 prime	probably benign
R1370:Smg1	UTSW	7	118,159,752 (GRCm38)	utr 3 prime	probably benign
R1591:Smg1	UTSW	7	118,156,919 (GRCm38)	utr 3 prime	probably benign
R1736:Smg1	UTSW	7	118,165,967 (GRCm38)	splice site	probably null
R1755:Smg1	UTSW	7	118,203,064 (GRCm38)	nonsense	probably null
R1765:Smg1	UTSW	7	118,139,715 (GRCm38)	missense	probably benign	0.03
R1789:Smg1	UTSW	7	118,145,798 (GRCm38)	missense	possibly damaging	0.73
R1845:Smg1	UTSW	7	118,154,622 (GRCm38)	utr 3 prime	probably benign
R1908:Smg1	UTSW	7	118,154,199 (GRCm38)	utr 3 prime	probably benign
R1909:Smg1	UTSW	7	118,154,199 (GRCm38)	utr 3 prime	probably benign
R1942:Smg1	UTSW	7	118,158,103 (GRCm38)	utr 3 prime	probably benign
R2064:Smg1	UTSW	7	118,156,867 (GRCm38)	utr 3 prime	probably benign
R2072:Smg1	UTSW	7	118,163,166 (GRCm38)	utr 3 prime	probably benign
R2154:Smg1	UTSW	7	118,158,076 (GRCm38)	utr 3 prime	probably benign
R2895:Smg1	UTSW	7	118,189,143 (GRCm38)	utr 3 prime	probably benign
R2915:Smg1	UTSW	7	118,210,879 (GRCm38)	splice site	probably benign
R3416:Smg1	UTSW	7	118,148,853 (GRCm38)	utr 3 prime	probably benign
R3417:Smg1	UTSW	7	118,148,853 (GRCm38)	utr 3 prime	probably benign
R3873:Smg1	UTSW	7	118,154,662 (GRCm38)	utr 3 prime	probably benign
R4082:Smg1	UTSW	7	118,160,246 (GRCm38)	utr 3 prime	probably benign
R4230:Smg1	UTSW	7	118,148,733 (GRCm38)	critical splice donor site	probably null
R4304:Smg1	UTSW	7	118,139,518 (GRCm38)	missense	probably benign	0.03
R4549:Smg1	UTSW	7	118,159,683 (GRCm38)	utr 3 prime	probably benign
R4571:Smg1	UTSW	7	118,139,465 (GRCm38)	missense	possibly damaging	0.72
R4638:Smg1	UTSW	7	118,195,926 (GRCm38)	utr 3 prime	probably benign
R4642:Smg1	UTSW	7	118,154,264 (GRCm38)	utr 3 prime	probably benign
R4656:Smg1	UTSW	7	118,212,951 (GRCm38)	missense	probably benign	0.00
R4754:Smg1	UTSW	7	118,156,731 (GRCm38)	utr 3 prime	probably benign
R4798:Smg1	UTSW	7	118,180,474 (GRCm38)	missense	probably benign	0.32
R4906:Smg1	UTSW	7	118,152,408 (GRCm38)	utr 3 prime	probably benign
R4978:Smg1	UTSW	7	118,154,247 (GRCm38)	utr 3 prime	probably benign
R4989:Smg1	UTSW	7	118,208,051 (GRCm38)	missense	probably benign
R4989:Smg1	UTSW	7	118,158,100 (GRCm38)	utr 3 prime	probably benign
R5026:Smg1	UTSW	7	118,193,545 (GRCm38)	utr 3 prime	probably benign
R5124:Smg1	UTSW	7	118,213,012 (GRCm38)	missense	probably benign	0.00
R5318:Smg1	UTSW	7	118,160,204 (GRCm38)	utr 3 prime	probably benign
R5356:Smg1	UTSW	7	118,195,133 (GRCm38)	utr 3 prime	probably benign
R5404:Smg1	UTSW	7	118,206,908 (GRCm38)	missense	probably damaging	1.00
R5423:Smg1	UTSW	7	118,146,071 (GRCm38)	missense	possibly damaging	0.70
R5441:Smg1	UTSW	7	118,195,081 (GRCm38)	utr 3 prime	probably benign
R5490:Smg1	UTSW	7	118,139,436 (GRCm38)	missense	possibly damaging	0.86
R5541:Smg1	UTSW	7	118,157,163 (GRCm38)	utr 3 prime	probably benign
R5564:Smg1	UTSW	7	118,189,819 (GRCm38)	utr 3 prime	probably benign
R5580:Smg1	UTSW	7	118,148,902 (GRCm38)	utr 3 prime	probably benign
R5600:Smg1	UTSW	7	118,167,884 (GRCm38)	utr 3 prime	probably benign
R5628:Smg1	UTSW	7	118,154,701 (GRCm38)	utr 3 prime	probably benign
R5646:Smg1	UTSW	7	118,212,559 (GRCm38)	missense	probably benign	0.42
R5656:Smg1	UTSW	7	118,154,664 (GRCm38)	utr 3 prime	probably benign
R5660:Smg1	UTSW	7	118,143,347 (GRCm38)	missense	probably benign	0.33
R5706:Smg1	UTSW	7	118,145,590 (GRCm38)	missense	possibly damaging	0.86
R5786:Smg1	UTSW	7	118,212,897 (GRCm38)	missense	probably benign	0.12
R5890:Smg1	UTSW	7	118,190,586 (GRCm38)	utr 3 prime	probably benign
R5912:Smg1	UTSW	7	118,154,586 (GRCm38)	utr 3 prime	probably benign
R5977:Smg1	UTSW	7	118,141,357 (GRCm38)	utr 3 prime	probably benign
R5993:Smg1	UTSW	7	118,140,509 (GRCm38)	missense	probably benign	0.33
R6161:Smg1	UTSW	7	118,163,330 (GRCm38)	utr 3 prime	probably benign
R6187:Smg1	UTSW	7	118,189,163 (GRCm38)	utr 3 prime	probably benign
R6264:Smg1	UTSW	7	118,166,087 (GRCm38)	utr 3 prime	probably benign
R6331:Smg1	UTSW	7	118,154,277 (GRCm38)	utr 3 prime	probably benign
R6561:Smg1	UTSW	7	118,166,077 (GRCm38)	utr 3 prime	probably benign
R6571:Smg1	UTSW	7	118,184,514 (GRCm38)	utr 3 prime	probably benign
R6736:Smg1	UTSW	7	118,157,166 (GRCm38)	utr 3 prime	probably benign
R6752:Smg1	UTSW	7	118,163,316 (GRCm38)	utr 3 prime	probably benign
R6777:Smg1	UTSW	7	118,189,117 (GRCm38)	utr 3 prime	probably benign
R6788:Smg1	UTSW	7	118,184,571 (GRCm38)	utr 3 prime	probably benign
R6883:Smg1	UTSW	7	118,168,180 (GRCm38)	utr 3 prime	probably benign
R6991:Smg1	UTSW	7	118,167,868 (GRCm38)	utr 3 prime	probably benign
R7056:Smg1	UTSW	7	118,146,400 (GRCm38)	splice site	probably benign
R7058:Smg1	UTSW	7	118,198,279 (GRCm38)	utr 3 prime	probably benign
R7100:Smg1	UTSW	7	118,184,520 (GRCm38)	missense	unknown
R7221:Smg1	UTSW	7	118,182,797 (GRCm38)	missense	possibly damaging	0.86
R7229:Smg1	UTSW	7	118,176,955 (GRCm38)	missense	probably benign	0.03
R7293:Smg1	UTSW	7	118,166,099 (GRCm38)	missense	unknown
R7361:Smg1	UTSW	7	118,184,977 (GRCm38)	missense	unknown
R7438:Smg1	UTSW	7	118,195,893 (GRCm38)	missense	unknown
R7686:Smg1	UTSW	7	118,167,858 (GRCm38)	missense	unknown
R7798:Smg1	UTSW	7	118,171,939 (GRCm38)	missense	possibly damaging	0.73
R7908:Smg1	UTSW	7	118,186,134 (GRCm38)	missense	unknown
R7923:Smg1	UTSW	7	118,143,322 (GRCm38)	missense	possibly damaging	0.96
R7978:Smg1	UTSW	7	118,193,655 (GRCm38)	missense	unknown
R7997:Smg1	UTSW	7	118,173,142 (GRCm38)	missense	unknown
R7997:Smg1	UTSW	7	118,173,141 (GRCm38)	missense	unknown
R8025:Smg1	UTSW	7	118,206,989 (GRCm38)	nonsense	probably null
R8056:Smg1	UTSW	7	118,160,366 (GRCm38)	missense	unknown
R8061:Smg1	UTSW	7	118,152,387 (GRCm38)	missense	unknown
R8095:Smg1	UTSW	7	118,173,062 (GRCm38)	missense	unknown
R8198:Smg1	UTSW	7	118,145,606 (GRCm38)	missense	probably benign	0.03
R8399:Smg1	UTSW	7	118,190,571 (GRCm38)	missense	unknown
R8445:Smg1	UTSW	7	118,136,977 (GRCm38)	missense	possibly damaging	0.72
R8519:Smg1	UTSW	7	118,171,759 (GRCm38)	utr 3 prime	probably benign
R8817:Smg1	UTSW	7	118,159,664 (GRCm38)	missense	unknown
R8832:Smg1	UTSW	7	118,139,783 (GRCm38)	missense	probably benign	0.33
R8855:Smg1	UTSW	7	118,206,899 (GRCm38)	missense	unknown
R8866:Smg1	UTSW	7	118,206,899 (GRCm38)	missense	unknown
R8946:Smg1	UTSW	7	118,152,677 (GRCm38)	missense	probably null
R8954:Smg1	UTSW	7	118,206,992 (GRCm38)	missense	probably damaging	1.00
R8967:Smg1	UTSW	7	118,166,516 (GRCm38)	missense	unknown
R9072:Smg1	UTSW	7	118,183,809 (GRCm38)	missense	unknown
R9090:Smg1	UTSW	7	118,212,563 (GRCm38)	missense	unknown
R9156:Smg1	UTSW	7	118,154,661 (GRCm38)	missense	unknown
R9198:Smg1	UTSW	7	118,195,956 (GRCm38)	missense	unknown
R9240:Smg1	UTSW	7	118,139,808 (GRCm38)	missense	probably benign	0.18
R9271:Smg1	UTSW	7	118,212,563 (GRCm38)	missense	unknown
R9289:Smg1	UTSW	7	118,145,416 (GRCm38)	missense	possibly damaging	0.53
R9378:Smg1	UTSW	7	118,178,775 (GRCm38)	nonsense	probably null
R9396:Smg1	UTSW	7	118,208,080 (GRCm38)	missense	unknown
R9469:Smg1	UTSW	7	118,140,551 (GRCm38)	missense	possibly damaging	0.72
R9539:Smg1	UTSW	7	118,145,753 (GRCm38)	missense	probably benign	0.03
R9549:Smg1	UTSW	7	118,196,031 (GRCm38)	missense	unknown
R9563:Smg1	UTSW	7	118,212,985 (GRCm38)	missense	unknown
R9564:Smg1	UTSW	7	118,212,985 (GRCm38)	missense	unknown
R9597:Smg1	UTSW	7	118,213,047 (GRCm38)	missense	unknown
R9643:Smg1	UTSW	7	118,156,710 (GRCm38)	missense	unknown
R9703:Smg1	UTSW	7	118,140,521 (GRCm38)	missense	possibly damaging	0.73
R9730:Smg1	UTSW	7	118,183,781 (GRCm38)	missense	unknown
Z1088:Smg1	UTSW	7	118,178,399 (GRCm38)	missense	possibly damaging	0.96
Z1088:Smg1	UTSW	7	118,168,661 (GRCm38)	nonsense	probably null
Z1088:Smg1	UTSW	7	118,154,635 (GRCm38)	utr 3 prime	probably benign
Z1176:Smg1	UTSW	7	118,206,907 (GRCm38)	missense	unknown
Z1176:Smg1	UTSW	7	118,206,887 (GRCm38)	missense	unknown
Z1177:Smg1	UTSW	7	118,213,033 (GRCm38)	missense	unknown
Z1177:Smg1	UTSW	7	118,168,608 (GRCm38)	missense	probably null

Predicted Primers

PCR Primer
(F):5'- AGACTCAGAGAGCCTTCTTCTC -3'
(R):5'- CATGGTAGGATTGTTCCAGGAAG -3'

Sequencing Primer
(F):5'- GAGCCTTCTTCTCCATTCTCATGAAG -3'
(R):5'- GGATTGTTCCAGGAAGTTATTAAGTC -3'

Posted On

2019-05-15