Incidental Mutation 'R7139:Trrap'
ID 553257
Institutional Source Beutler Lab
Gene Symbol Trrap
Ensembl Gene ENSMUSG00000045482
Gene Name transformation/transcription domain-associated protein
Synonyms transactivation/transformation-domain associated protein
Accession Numbers
Essential gene? Essential (E-score: 1.000) question?
Stock # R7139 (G1)
Quality Score 225.009
Status Not validated
Chromosome 5
Chromosomal Location 144704547-144796588 bp(+) (GRCm39)
Type of Mutation missense
DNA Base Change (assembly) C to A at 144739988 bp (GRCm39)
Zygosity Heterozygous
Amino Acid Change Leucine to Isoleucine at position 1137 (L1137I)
Ref Sequence ENSEMBL: ENSMUSP00000098035 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000038980] [ENSMUST00000094120] [ENSMUST00000100467] [ENSMUST00000213013]
AlphaFold no structure available at present
Predicted Effect probably benign
Transcript: ENSMUST00000038980
AA Change: L1137I

PolyPhen 2 Score 0.259 (Sensitivity: 0.91; Specificity: 0.88)
SMART Domains Protein: ENSMUSP00000042544
Gene: ENSMUSG00000045482
AA Change: L1137I

DomainStartEndE-ValueType
low complexity region 482 527 N/A INTRINSIC
low complexity region 529 540 N/A INTRINSIC
Blast:PI3Kc 765 864 1e-13 BLAST
SCOP:d1gw5a_ 1184 1664 2e-6 SMART
low complexity region 1832 1843 N/A INTRINSIC
low complexity region 1866 1881 N/A INTRINSIC
low complexity region 2289 2303 N/A INTRINSIC
Pfam:FAT 2830 3174 4.7e-69 PFAM
low complexity region 3363 3376 N/A INTRINSIC
low complexity region 3407 3418 N/A INTRINSIC
PI3Kc 3509 3798 5.11e-8 SMART
FATC 3797 3829 1.89e-3 SMART
Predicted Effect probably benign
Transcript: ENSMUST00000094120
AA Change: L1137I

PolyPhen 2 Score 0.143 (Sensitivity: 0.92; Specificity: 0.86)
SMART Domains Protein: ENSMUSP00000091668
Gene: ENSMUSG00000045482
AA Change: L1137I

DomainStartEndE-ValueType
low complexity region 482 527 N/A INTRINSIC
low complexity region 529 540 N/A INTRINSIC
Blast:PI3Kc 765 864 1e-13 BLAST
SCOP:d1gw5a_ 1184 1682 2e-6 SMART
low complexity region 1850 1861 N/A INTRINSIC
low complexity region 1884 1899 N/A INTRINSIC
low complexity region 2307 2321 N/A INTRINSIC
Pfam:FAT 2848 3203 1.1e-68 PFAM
low complexity region 3392 3405 N/A INTRINSIC
low complexity region 3436 3447 N/A INTRINSIC
PI3Kc 3538 3827 5.11e-8 SMART
FATC 3826 3858 1.89e-3 SMART
Predicted Effect possibly damaging
Transcript: ENSMUST00000100467
AA Change: L1137I

PolyPhen 2 Score 0.650 (Sensitivity: 0.87; Specificity: 0.91)
SMART Domains Protein: ENSMUSP00000098035
Gene: ENSMUSG00000045482
AA Change: L1137I

DomainStartEndE-ValueType
low complexity region 482 527 N/A INTRINSIC
low complexity region 529 540 N/A INTRINSIC
Blast:PI3Kc 765 864 1e-13 BLAST
SCOP:d1gw5a_ 1184 1664 2e-6 SMART
low complexity region 1832 1843 N/A INTRINSIC
low complexity region 1866 1881 N/A INTRINSIC
low complexity region 2289 2303 N/A INTRINSIC
Pfam:FAT 2830 3174 4.7e-69 PFAM
low complexity region 3381 3394 N/A INTRINSIC
low complexity region 3425 3436 N/A INTRINSIC
PI3Kc 3527 3816 5.11e-8 SMART
FATC 3815 3847 1.89e-3 SMART
Predicted Effect
SMART Domains Protein: ENSMUSP00000122021
Gene: ENSMUSG00000045482
AA Change: L851I

DomainStartEndE-ValueType
low complexity region 197 242 N/A INTRINSIC
low complexity region 244 255 N/A INTRINSIC
SCOP:d1gw5a_ 474 1003 9e-7 SMART
Blast:PI3Kc 480 579 1e-13 BLAST
low complexity region 1083 1092 N/A INTRINSIC
low complexity region 1572 1583 N/A INTRINSIC
low complexity region 1606 1621 N/A INTRINSIC
low complexity region 2029 2043 N/A INTRINSIC
Pfam:FAT 2570 2914 1.5e-69 PFAM
low complexity region 3121 3134 N/A INTRINSIC
low complexity region 3165 3176 N/A INTRINSIC
PI3Kc 3267 3556 5.11e-8 SMART
FATC 3555 3587 1.89e-3 SMART
Predicted Effect possibly damaging
Transcript: ENSMUST00000213013
AA Change: L1138I

PolyPhen 2 Score 0.762 (Sensitivity: 0.85; Specificity: 0.92)
Coding Region Coverage
  • 1x: 100.0%
  • 3x: 100.0%
  • 10x: 99.7%
  • 20x: 99.1%
Validation Efficiency
MGI Phenotype FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a large multidomain protein of the phosphoinositide 3-kinase-related kinases (PIKK) family. The encoded protein is a common component of many histone acetyltransferase (HAT) complexes and plays a role in transcription and DNA repair by recruiting HAT complexes to chromatin. Deregulation of this gene may play a role in several types of cancer including glioblastoma multiforme. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011]
PHENOTYPE: Homozygous embryos die prior to E3.5 and exhibit embryonic and extraembryonic tissue disorganization. Mitotic abnormalities were also noted in homozygous cells. [provided by MGI curators]
Allele List at MGI
Other mutations in this stock
Total: 79 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
2510039O18Rik A G 4: 148,026,295 (GRCm39) R272G possibly damaging Het
4930512M02Rik T A 11: 11,540,078 (GRCm39) N179Y unknown Het
4930562C15Rik A T 16: 4,668,048 (GRCm39) M480L probably benign Het
Abcd4 A G 12: 84,653,072 (GRCm39) C377R probably benign Het
Adam23 C A 1: 63,584,736 (GRCm39) D381E probably damaging Het
Angpt1 T A 15: 42,539,747 (GRCm39) Q37H probably damaging Het
Apeh A T 9: 107,969,345 (GRCm39) F260I probably damaging Het
Cadps2 T C 6: 23,410,888 (GRCm39) Y681C probably damaging Het
Ccdc162 T C 10: 41,542,717 (GRCm39) M386V possibly damaging Het
Celsr2 T C 3: 108,322,675 (GRCm39) S46G unknown Het
Cfc1 T C 1: 34,575,560 (GRCm39) L78P probably benign Het
Chd7 T C 4: 8,865,865 (GRCm39) V2724A probably benign Het
Clca3a1 A T 3: 144,461,063 (GRCm39) V196E possibly damaging Het
Cma1 T C 14: 56,181,273 (GRCm39) H44R probably damaging Het
Cnot2 T C 10: 116,330,924 (GRCm39) N394S probably benign Het
Cplx3 A T 9: 57,522,879 (GRCm39) H160Q probably benign Het
Cstf3 A T 2: 104,483,409 (GRCm39) I372F possibly damaging Het
Cyb5rl A C 4: 106,928,208 (GRCm39) I115L probably benign Het
D5Ertd579e A G 5: 36,771,320 (GRCm39) L1025P probably damaging Het
Dmtn T C 14: 70,854,867 (GRCm39) N36S probably benign Het
Dnah6 A G 6: 73,112,663 (GRCm39) V1647A probably damaging Het
Dock6 T C 9: 21,712,572 (GRCm39) Y2063C probably damaging Het
Dst T A 1: 34,338,888 (GRCm39) D5149E probably damaging Het
Fancl A G 11: 26,353,358 (GRCm39) M85V probably benign Het
Fgd2 T A 17: 29,592,229 (GRCm39) F387Y probably damaging Het
Fshr A T 17: 89,293,589 (GRCm39) I363N possibly damaging Het
Glce G T 9: 61,977,716 (GRCm39) S56* probably null Het
Gm26727 A T 2: 67,263,381 (GRCm39) S49T unknown Het
Gm36210 T A 7: 4,902,277 (GRCm39) D131V probably damaging Het
Gm5089 T C 14: 122,673,403 (GRCm39) D106G unknown Het
Gm5622 G T 14: 51,893,339 (GRCm39) E89* probably null Het
H2-Eb2 C T 17: 34,553,395 (GRCm39) R194W probably benign Het
Hivep1 A T 13: 42,313,430 (GRCm39) E1890V probably benign Het
Ighv1-53 A T 12: 115,122,441 (GRCm39) C5* probably null Het
Ighv2-5 T A 12: 113,649,219 (GRCm39) Y78F probably benign Het
Il9 C T 13: 56,628,426 (GRCm39) V88I probably benign Het
Kidins220 A G 12: 25,044,820 (GRCm39) T163A probably damaging Het
Lama4 G T 10: 38,951,491 (GRCm39) D1079Y probably damaging Het
Lrrc34 T C 3: 30,679,036 (GRCm39) I354V probably benign Het
Macroh2a2 T A 10: 61,593,674 (GRCm39) M1L unknown Het
Mpeg1 A T 19: 12,439,078 (GRCm39) T179S probably benign Het
Mrgpra2a A T 7: 47,076,337 (GRCm39) L307H probably damaging Het
Mst1 G A 9: 107,960,027 (GRCm39) R328H probably damaging Het
Muc21 TCCTGAGGCAGTGCTGGATACAGGGGTGGTTGGGGTGGGTGAAGAGCCTGAGGCAGTGCTGGAT TCCTGAGGCAGTGCTGGAT 17: 35,933,525 (GRCm39) probably benign Het
Nav3 C A 10: 109,689,338 (GRCm39) S313I probably benign Het
Nmt2 T G 2: 3,285,352 (GRCm39) S7A probably benign Het
Nsmce1 T C 7: 125,068,254 (GRCm39) S197G probably benign Het
Ociad2 A G 5: 73,493,218 (GRCm39) V4A probably benign Het
Or56a41 G T 7: 104,742,005 (GRCm39) T7K probably benign Het
Osmr T C 15: 6,850,569 (GRCm39) D679G possibly damaging Het
Pappa T A 4: 65,107,687 (GRCm39) F699L probably benign Het
Parp8 T A 13: 117,161,802 (GRCm39) M40L probably benign Het
Pcyox1 A T 6: 86,371,519 (GRCm39) N122K possibly damaging Het
Pkd1l1 T C 11: 8,840,737 (GRCm39) S1224G Het
Pkd1l3 T A 8: 110,362,972 (GRCm39) S1088T probably damaging Het
Prrt1 T C 17: 34,850,051 (GRCm39) V155A probably benign Het
Rbm6 A C 9: 107,730,410 (GRCm39) D79E probably damaging Het
Sec31b A T 19: 44,507,375 (GRCm39) S819T probably benign Het
Slc22a27 A T 19: 7,903,912 (GRCm39) I75N probably damaging Het
Slc25a54 G A 3: 109,005,905 (GRCm39) G138R probably damaging Het
Slc6a12 T C 6: 121,342,278 (GRCm39) S612P probably benign Het
Slc7a2 A T 8: 41,368,050 (GRCm39) I605F probably benign Het
Slit2 A G 5: 48,402,025 (GRCm39) T805A probably benign Het
Strbp A T 2: 37,514,514 (GRCm39) H308Q probably benign Het
Stxbp4 G A 11: 90,497,835 (GRCm39) Q155* probably null Het
Sybu A T 15: 44,541,110 (GRCm39) N317K possibly damaging Het
Taok1 G A 11: 77,462,459 (GRCm39) S210F probably damaging Het
Tapbp A G 17: 34,139,022 (GRCm39) D72G possibly damaging Het
Thbd G T 2: 148,248,461 (GRCm39) T469K probably benign Het
Tia1 T C 6: 86,404,670 (GRCm39) Y302H possibly damaging Het
Tlr4 T C 4: 66,758,520 (GRCm39) F438L probably benign Het
Tmem235 C T 11: 117,751,723 (GRCm39) S49L probably damaging Het
Trip4 A G 9: 65,792,503 (GRCm39) probably benign Het
Vmo1 T C 11: 70,404,674 (GRCm39) E109G probably benign Het
Wdfy4 T C 14: 32,873,535 (GRCm39) Y258C Het
Wdr91 T G 6: 34,885,198 (GRCm39) N121T possibly damaging Het
Zfp39 T C 11: 58,781,385 (GRCm39) H459R probably damaging Het
Zfp936 T A 7: 42,839,715 (GRCm39) I394K possibly damaging Het
Zpr1 G A 9: 46,192,357 (GRCm39) D423N probably damaging Het
Other mutations in Trrap
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL00095:Trrap APN 5 144,716,784 (GRCm39) splice site probably benign
IGL00470:Trrap APN 5 144,754,848 (GRCm39) missense probably damaging 1.00
IGL00490:Trrap APN 5 144,762,035 (GRCm39) missense probably benign 0.40
IGL01072:Trrap APN 5 144,721,065 (GRCm39) splice site probably benign
IGL01087:Trrap APN 5 144,783,349 (GRCm39) missense probably damaging 0.99
IGL01300:Trrap APN 5 144,741,628 (GRCm39) missense probably damaging 1.00
IGL01350:Trrap APN 5 144,767,779 (GRCm39) missense possibly damaging 0.92
IGL01410:Trrap APN 5 144,767,831 (GRCm39) missense probably benign 0.00
IGL01571:Trrap APN 5 144,770,097 (GRCm39) splice site probably benign
IGL01748:Trrap APN 5 144,770,150 (GRCm39) missense probably damaging 1.00
IGL01839:Trrap APN 5 144,758,685 (GRCm39) missense probably damaging 1.00
IGL01976:Trrap APN 5 144,793,799 (GRCm39) missense probably benign 0.00
IGL02075:Trrap APN 5 144,765,304 (GRCm39) missense probably benign 0.00
IGL02127:Trrap APN 5 144,753,243 (GRCm39) missense probably benign 0.22
IGL02131:Trrap APN 5 144,777,246 (GRCm39) missense probably damaging 1.00
IGL02287:Trrap APN 5 144,769,348 (GRCm39) missense probably damaging 1.00
IGL02301:Trrap APN 5 144,714,727 (GRCm39) missense probably benign 0.05
IGL02336:Trrap APN 5 144,735,200 (GRCm39) missense probably benign 0.39
IGL02526:Trrap APN 5 144,761,360 (GRCm39) missense probably benign 0.00
IGL02873:Trrap APN 5 144,777,889 (GRCm39) splice site probably benign
IGL02953:Trrap APN 5 144,752,774 (GRCm39) missense probably damaging 0.99
IGL03404:Trrap APN 5 144,769,996 (GRCm39) missense probably benign 0.00
Buffer UTSW 5 144,771,014 (GRCm39) missense probably benign 0.06
Card-tower UTSW 5 144,741,576 (GRCm39) missense probably damaging 1.00
Cookie UTSW 5 144,730,859 (GRCm39) missense probably damaging 1.00
Glass_house UTSW 5 144,782,287 (GRCm39) missense possibly damaging 0.67
Immovable UTSW 5 144,727,665 (GRCm39) missense possibly damaging 0.66
R5049_trrap_520 UTSW 5 144,763,527 (GRCm39) missense probably damaging 1.00
R7167_Trrap_977 UTSW 5 144,776,424 (GRCm39) missense probably benign 0.39
vitreous UTSW 5 144,742,537 (GRCm39) missense probably damaging 1.00
PIT4243001:Trrap UTSW 5 144,733,781 (GRCm39) missense probably benign 0.00
PIT4466001:Trrap UTSW 5 144,765,410 (GRCm39) missense probably benign 0.02
R0062:Trrap UTSW 5 144,719,003 (GRCm39) splice site probably benign
R0062:Trrap UTSW 5 144,719,003 (GRCm39) splice site probably benign
R0112:Trrap UTSW 5 144,759,571 (GRCm39) nonsense probably null
R0126:Trrap UTSW 5 144,742,560 (GRCm39) nonsense probably null
R0257:Trrap UTSW 5 144,741,045 (GRCm39) missense probably benign 0.31
R0325:Trrap UTSW 5 144,753,205 (GRCm39) missense probably benign 0.05
R0376:Trrap UTSW 5 144,753,149 (GRCm39) missense probably benign 0.03
R0396:Trrap UTSW 5 144,751,366 (GRCm39) missense probably damaging 0.99
R0448:Trrap UTSW 5 144,776,377 (GRCm39) missense possibly damaging 0.66
R0454:Trrap UTSW 5 144,783,287 (GRCm39) missense probably damaging 1.00
R0711:Trrap UTSW 5 144,790,309 (GRCm39) missense probably damaging 1.00
R0827:Trrap UTSW 5 144,751,640 (GRCm39) missense probably benign 0.00
R1005:Trrap UTSW 5 144,742,537 (GRCm39) missense probably damaging 1.00
R1147:Trrap UTSW 5 144,741,576 (GRCm39) missense probably damaging 1.00
R1147:Trrap UTSW 5 144,741,576 (GRCm39) missense probably damaging 1.00
R1179:Trrap UTSW 5 144,714,749 (GRCm39) missense possibly damaging 0.94
R1218:Trrap UTSW 5 144,753,219 (GRCm39) missense probably damaging 1.00
R1264:Trrap UTSW 5 144,726,409 (GRCm39) splice site probably benign
R1374:Trrap UTSW 5 144,783,428 (GRCm39) missense probably damaging 1.00
R1401:Trrap UTSW 5 144,794,232 (GRCm39) missense possibly damaging 0.93
R1480:Trrap UTSW 5 144,755,123 (GRCm39) missense probably benign
R1538:Trrap UTSW 5 144,774,012 (GRCm39) missense possibly damaging 0.65
R1751:Trrap UTSW 5 144,751,385 (GRCm39) critical splice donor site probably null
R1779:Trrap UTSW 5 144,765,400 (GRCm39) missense probably benign 0.01
R1782:Trrap UTSW 5 144,759,513 (GRCm39) missense possibly damaging 0.93
R1792:Trrap UTSW 5 144,790,396 (GRCm39) missense possibly damaging 0.87
R1859:Trrap UTSW 5 144,767,761 (GRCm39) missense probably benign 0.04
R1861:Trrap UTSW 5 144,752,727 (GRCm39) splice site probably null
R1902:Trrap UTSW 5 144,752,863 (GRCm39) missense probably damaging 1.00
R1903:Trrap UTSW 5 144,752,863 (GRCm39) missense probably damaging 1.00
R2021:Trrap UTSW 5 144,790,298 (GRCm39) missense possibly damaging 0.94
R2026:Trrap UTSW 5 144,739,854 (GRCm39) missense possibly damaging 0.86
R2036:Trrap UTSW 5 144,765,372 (GRCm39) missense probably benign 0.08
R2099:Trrap UTSW 5 144,719,049 (GRCm39) missense possibly damaging 0.46
R2108:Trrap UTSW 5 144,762,684 (GRCm39) missense probably benign 0.01
R2113:Trrap UTSW 5 144,781,021 (GRCm39) missense probably damaging 1.00
R2174:Trrap UTSW 5 144,758,665 (GRCm39) missense probably benign 0.40
R2442:Trrap UTSW 5 144,754,776 (GRCm39) missense probably damaging 1.00
R2568:Trrap UTSW 5 144,780,179 (GRCm39) critical splice donor site probably null
R3442:Trrap UTSW 5 144,729,062 (GRCm39) missense probably benign 0.03
R3853:Trrap UTSW 5 144,728,975 (GRCm39) missense probably damaging 1.00
R4401:Trrap UTSW 5 144,780,128 (GRCm39) missense possibly damaging 0.60
R4493:Trrap UTSW 5 144,767,858 (GRCm39) missense probably benign 0.21
R4524:Trrap UTSW 5 144,762,131 (GRCm39) missense probably benign 0.38
R4569:Trrap UTSW 5 144,728,928 (GRCm39) missense probably benign 0.13
R4672:Trrap UTSW 5 144,722,290 (GRCm39) missense probably damaging 0.97
R4732:Trrap UTSW 5 144,753,380 (GRCm39) missense probably damaging 1.00
R4733:Trrap UTSW 5 144,753,380 (GRCm39) missense probably damaging 1.00
R4791:Trrap UTSW 5 144,740,087 (GRCm39) missense probably damaging 1.00
R4795:Trrap UTSW 5 144,769,298 (GRCm39) missense probably benign 0.06
R4827:Trrap UTSW 5 144,737,758 (GRCm39) missense probably benign 0.02
R4839:Trrap UTSW 5 144,782,402 (GRCm39) missense probably damaging 1.00
R4915:Trrap UTSW 5 144,742,545 (GRCm39) missense probably damaging 0.99
R4951:Trrap UTSW 5 144,742,530 (GRCm39) missense possibly damaging 0.65
R4959:Trrap UTSW 5 144,793,770 (GRCm39) missense probably damaging 1.00
R5049:Trrap UTSW 5 144,763,527 (GRCm39) missense probably damaging 1.00
R5074:Trrap UTSW 5 144,787,989 (GRCm39) missense probably damaging 1.00
R5236:Trrap UTSW 5 144,754,596 (GRCm39) missense probably benign 0.07
R5281:Trrap UTSW 5 144,750,313 (GRCm39) missense probably benign 0.13
R5322:Trrap UTSW 5 144,781,034 (GRCm39) missense probably damaging 1.00
R5457:Trrap UTSW 5 144,786,787 (GRCm39) missense probably damaging 1.00
R5590:Trrap UTSW 5 144,719,075 (GRCm39) missense probably benign 0.05
R5799:Trrap UTSW 5 144,767,755 (GRCm39) missense probably benign
R5885:Trrap UTSW 5 144,731,603 (GRCm39) missense probably damaging 1.00
R5905:Trrap UTSW 5 144,786,730 (GRCm39) missense possibly damaging 0.95
R5908:Trrap UTSW 5 144,723,518 (GRCm39) missense probably damaging 0.96
R5956:Trrap UTSW 5 144,744,201 (GRCm39) splice site silent
R5992:Trrap UTSW 5 144,746,994 (GRCm39) missense probably benign 0.00
R6017:Trrap UTSW 5 144,781,051 (GRCm39) missense probably damaging 1.00
R6029:Trrap UTSW 5 144,762,724 (GRCm39) missense possibly damaging 0.75
R6029:Trrap UTSW 5 144,754,489 (GRCm39) missense possibly damaging 0.94
R6117:Trrap UTSW 5 144,739,771 (GRCm39) missense possibly damaging 0.78
R6166:Trrap UTSW 5 144,718,791 (GRCm39) missense possibly damaging 0.66
R6234:Trrap UTSW 5 144,776,523 (GRCm39) splice site probably null
R6288:Trrap UTSW 5 144,748,802 (GRCm39) missense probably damaging 1.00
R6290:Trrap UTSW 5 144,741,828 (GRCm39) missense probably damaging 1.00
R6316:Trrap UTSW 5 144,750,336 (GRCm39) missense probably benign 0.02
R6398:Trrap UTSW 5 144,727,680 (GRCm39) missense possibly damaging 0.83
R6413:Trrap UTSW 5 144,720,856 (GRCm39) missense possibly damaging 0.83
R6499:Trrap UTSW 5 144,793,812 (GRCm39) missense probably damaging 1.00
R6529:Trrap UTSW 5 144,771,014 (GRCm39) missense probably benign 0.06
R6574:Trrap UTSW 5 144,752,360 (GRCm39) critical splice donor site probably null
R6631:Trrap UTSW 5 144,708,460 (GRCm39) missense possibly damaging 0.94
R6727:Trrap UTSW 5 144,793,760 (GRCm39) missense probably damaging 1.00
R6776:Trrap UTSW 5 144,788,066 (GRCm39) nonsense probably null
R6914:Trrap UTSW 5 144,720,853 (GRCm39) missense possibly damaging 0.83
R6942:Trrap UTSW 5 144,720,853 (GRCm39) missense possibly damaging 0.83
R6945:Trrap UTSW 5 144,727,665 (GRCm39) missense possibly damaging 0.66
R7023:Trrap UTSW 5 144,728,964 (GRCm39) missense possibly damaging 0.64
R7107:Trrap UTSW 5 144,733,945 (GRCm39) missense probably benign 0.05
R7148:Trrap UTSW 5 144,758,613 (GRCm39) missense possibly damaging 0.77
R7167:Trrap UTSW 5 144,776,424 (GRCm39) missense probably benign 0.39
R7171:Trrap UTSW 5 144,730,859 (GRCm39) missense probably damaging 1.00
R7205:Trrap UTSW 5 144,779,517 (GRCm39) missense possibly damaging 0.94
R7215:Trrap UTSW 5 144,733,945 (GRCm39) missense probably benign 0.05
R7255:Trrap UTSW 5 144,795,764 (GRCm39) missense probably damaging 1.00
R7261:Trrap UTSW 5 144,782,287 (GRCm39) missense possibly damaging 0.67
R7264:Trrap UTSW 5 144,751,333 (GRCm39) missense probably benign 0.05
R7372:Trrap UTSW 5 144,726,208 (GRCm39) missense probably benign
R7447:Trrap UTSW 5 144,776,284 (GRCm39) missense probably damaging 0.97
R7449:Trrap UTSW 5 144,788,019 (GRCm39) missense probably damaging 1.00
R7655:Trrap UTSW 5 144,779,422 (GRCm39) missense probably damaging 1.00
R7656:Trrap UTSW 5 144,779,422 (GRCm39) missense probably damaging 1.00
R7662:Trrap UTSW 5 144,769,321 (GRCm39) missense probably benign 0.00
R7716:Trrap UTSW 5 144,713,956 (GRCm39) missense possibly damaging 0.73
R8143:Trrap UTSW 5 144,772,707 (GRCm39) splice site probably null
R8183:Trrap UTSW 5 144,765,343 (GRCm39) missense probably benign 0.01
R8265:Trrap UTSW 5 144,722,344 (GRCm39) missense possibly damaging 0.53
R8273:Trrap UTSW 5 144,727,975 (GRCm39) missense probably damaging 1.00
R8556:Trrap UTSW 5 144,762,747 (GRCm39) missense probably benign 0.44
R8674:Trrap UTSW 5 144,727,842 (GRCm39) missense probably benign 0.02
R8777:Trrap UTSW 5 144,773,949 (GRCm39) missense probably benign 0.10
R8777-TAIL:Trrap UTSW 5 144,773,949 (GRCm39) missense probably benign 0.10
R8817:Trrap UTSW 5 144,782,348 (GRCm39) missense probably damaging 1.00
R8841:Trrap UTSW 5 144,781,021 (GRCm39) missense probably damaging 1.00
R8871:Trrap UTSW 5 144,758,649 (GRCm39) missense probably benign 0.30
R8937:Trrap UTSW 5 144,757,063 (GRCm39) missense probably damaging 1.00
R8966:Trrap UTSW 5 144,740,162 (GRCm39) missense probably damaging 0.96
R9010:Trrap UTSW 5 144,783,226 (GRCm39) missense probably damaging 1.00
R9095:Trrap UTSW 5 144,733,961 (GRCm39) missense probably damaging 1.00
R9127:Trrap UTSW 5 144,767,830 (GRCm39) missense probably benign 0.16
R9132:Trrap UTSW 5 144,726,362 (GRCm39) missense probably benign 0.03
R9224:Trrap UTSW 5 144,708,049 (GRCm39) missense possibly damaging 0.70
R9338:Trrap UTSW 5 144,727,925 (GRCm39) missense probably benign
R9380:Trrap UTSW 5 144,769,981 (GRCm39) missense probably benign
R9404:Trrap UTSW 5 144,752,225 (GRCm39) missense possibly damaging 0.85
R9457:Trrap UTSW 5 144,763,478 (GRCm39) missense probably damaging 1.00
R9464:Trrap UTSW 5 144,763,517 (GRCm39) missense probably damaging 0.99
R9504:Trrap UTSW 5 144,742,904 (GRCm39) missense probably damaging 1.00
R9583:Trrap UTSW 5 144,777,330 (GRCm39) missense probably damaging 1.00
R9584:Trrap UTSW 5 144,777,330 (GRCm39) missense probably damaging 1.00
R9585:Trrap UTSW 5 144,777,330 (GRCm39) missense probably damaging 1.00
R9608:Trrap UTSW 5 144,780,128 (GRCm39) missense possibly damaging 0.60
R9728:Trrap UTSW 5 144,726,193 (GRCm39) missense probably benign 0.22
R9782:Trrap UTSW 5 144,758,716 (GRCm39) missense probably damaging 0.99
X0060:Trrap UTSW 5 144,780,171 (GRCm39) missense probably damaging 0.96
Z1088:Trrap UTSW 5 144,771,007 (GRCm39) missense probably benign 0.00
Z1177:Trrap UTSW 5 144,756,518 (GRCm39) missense probably damaging 1.00
Z1177:Trrap UTSW 5 144,747,154 (GRCm39) missense
Z1177:Trrap UTSW 5 144,793,761 (GRCm39) missense probably damaging 1.00
Predicted Primers PCR Primer
(F):5'- CACAGCCATGTTCCACAGTG -3'
(R):5'- ATGACCTACCTCTCCAGTCAGG -3'

Sequencing Primer
(F):5'- ATGCCATAGCTATCTGTATGGC -3'
(R):5'- GTCAGGTCCATCATTACAAAGAGCAG -3'
Posted On 2019-05-15