Mutagenetix > Incidental Mutation

Incidental Mutation 'R7140:Tenm3'

553405

Institutional Source

Beutler Lab

Gene Symbol

Tenm3

Ensembl Gene

ENSMUSG00000031561

Gene Name

teneurin transmembrane protein 3

Synonyms

Ten-m3, Odz3, 2610100B16Rik

Accession Numbers

Essential gene?

Possibly essential (E-score: 0.598) question?

Stock #

R7140 (G1)

Quality Score

225.009

Status

Validated

Chromosome

Chromosomal Location

48227682-48843951 bp(-) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

A to T at 48292236 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Cysteine to Serine at position 1097 (C1097S)

Ref Sequence

ENSEMBL: ENSMUSP00000033965 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000033965] [ENSMUST00000190840]

AlphaFold

no structure available at present

Predicted Effect

probably damaging
Transcript: ENSMUST00000033965
AA Change: C1097S

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)

SMART Domains

Protein: ENSMUSP00000033965
Gene: ENSMUSG00000031561
AA Change: C1097S

Domain	Start	End	E-Value	Type
Pfam:Ten_N	11	177	6.9e-91	PFAM
Pfam:Ten_N	171	308	1e-72	PFAM
transmembrane domain	309	331	N/A	INTRINSIC
EGF	517	545	2.32e-1	SMART
EGF_like	548	576	4.11e1	SMART
EGF	581	610	1.69e1	SMART
EGF	613	642	1.35e-2	SMART
EGF	647	677	6.11e-1	SMART
EGF	680	708	7.95e0	SMART
EGF	711	739	1.28e1	SMART
EGF	751	783	1.64e-1	SMART
PDB:1RWL\|A	1276	1511	9e-6	PDB
low complexity region	2593	2602	N/A	INTRINSIC
Pfam:Tox-GHH	2631	2708	1.5e-34	PFAM

Predicted Effect

possibly damaging
Transcript: ENSMUST00000190840
AA Change: C1088S

PolyPhen 2 Score 0.915 (Sensitivity: 0.81; Specificity: 0.94)

SMART Domains

Protein: ENSMUSP00000140141
Gene: ENSMUSG00000031561
AA Change: C1088S

Domain	Start	End	E-Value	Type
Pfam:Ten_N	10	182	7.6e-77	PFAM
Pfam:Ten_N	168	308	6.6e-50	PFAM
transmembrane domain	309	331	N/A	INTRINSIC
EGF	517	545	2.32e-1	SMART
EGF_like	548	576	4.11e1	SMART
EGF	581	610	1.69e1	SMART
EGF	613	642	1.35e-2	SMART
EGF	647	677	6.11e-1	SMART
EGF	680	708	7.95e0	SMART
EGF	711	739	1.28e1	SMART
EGF	751	783	1.64e-1	SMART
PDB:1RWL\|A	1276	1511	9e-6	PDB
low complexity region	2593	2602	N/A	INTRINSIC
Pfam:Tox-GHH	2630	2708	3.2e-35	PFAM

Coding Region Coverage

1x: 100.0%
3x: 99.9%
10x: 99.7%
20x: 99.2%

Validation Efficiency

99% (70/71)

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a large transmembrane protein that may be involved in the regulation of neuronal development. Mutation in this gene causes microphthalmia. [provided by RefSeq, Aug 2015]
PHENOTYPE: Mice homozygous for a null mutation display abnormal ipsilateral retinal ganglion cell projections and impaired performance in visually mediated behavioral tasks. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 69 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Adgra2	T	C	8: 27,120,901 (GRCm38)		probably null	Het
Ap2a2	G	A	7: 141,598,864 (GRCm38)	A148T	probably benign	Het
Arhgef3	A	T	14: 27,401,707 (GRCm38)	N442Y	probably damaging	Het
B3gat3	A	G	19: 8,925,852 (GRCm38)	Y191C	probably damaging	Het
B430306N03Rik	A	T	17: 48,322,455 (GRCm38)	K203*	probably null	Het
C1qtnf6	T	A	15: 78,525,083 (GRCm38)	Y188F	probably benign	Het
Capn10	T	C	1: 92,945,271 (GRCm38)	V573A	possibly damaging	Het
Cbx4	T	C	11: 119,081,928 (GRCm38)	Y207C	probably damaging	Het
Ccdc43	G	T	11: 102,688,869 (GRCm38)		probably null	Het
Ccng2	C	A	5: 93,268,755 (GRCm38)	P45Q	probably benign	Het
Cd86	T	C	16: 36,620,901 (GRCm38)	H68R	probably benign	Het
Cmtm4	A	G	8: 104,355,195 (GRCm38)	Y187H	probably damaging	Het
Cst11	T	C	2: 148,768,729 (GRCm38)	N134S	probably benign	Het
Cyp3a25	A	T	5: 146,003,045 (GRCm38)	F51I	probably benign	Het
Dnhd1	A	G	7: 105,693,766 (GRCm38)	E1439G	probably benign	Het
Dock4	T	C	12: 40,636,159 (GRCm38)	V131A	probably benign	Het
Dpysl2	A	G	14: 66,862,533 (GRCm38)	S85P	probably benign	Het
Dync1i2	A	G	2: 71,247,939 (GRCm38)	H324R	probably benign	Het
Elf1	A	G	14: 79,567,270 (GRCm38)	D162G	probably benign	Het
Eri3	G	A	4: 117,649,407 (GRCm38)		probably null	Het
Fbxl21	T	C	13: 56,532,332 (GRCm38)	S203P	probably damaging	Het
Foxi1	G	A	11: 34,205,758 (GRCm38)	R291C	probably damaging	Het
Gm13089	T	G	4: 143,698,432 (GRCm38)	H147P	probably benign	Het
Gprin3	C	T	6: 59,355,143 (GRCm38)	A60T	possibly damaging	Het
Hecw1	A	G	13: 14,316,533 (GRCm38)	C212R	probably benign	Het
Hivep3	T	C	4: 120,097,121 (GRCm38)	L878P	probably damaging	Het
Hs6st3	A	T	14: 119,139,102 (GRCm38)	N230Y	probably damaging	Het
Htr3b	A	G	9: 48,937,141 (GRCm38)	V268A	possibly damaging	Het
Ip6k3	T	C	17: 27,144,995 (GRCm38)	T360A	probably damaging	Het
Izumo1	A	G	7: 45,626,112 (GRCm38)	T282A	probably benign	Het
Kidins220	T	A	12: 25,036,624 (GRCm38)	I1019N	probably damaging	Het
Med13l	T	C	5: 118,741,972 (GRCm38)	V1043A	probably benign	Het
Mon2	C	T	10: 123,035,453 (GRCm38)	V420I	probably benign	Het
Naip6	T	A	13: 100,300,200 (GRCm38)	Y605F	possibly damaging	Het
Nek7	A	G	1: 138,487,055 (GRCm38)	I285T	probably benign	Het
Notch3	A	G	17: 32,156,377 (GRCm38)	V357A	possibly damaging	Het
Nrxn1	G	A	17: 91,088,764 (GRCm38)		probably benign	Het
Nutm1	G	A	2: 112,250,056 (GRCm38)	R505C	probably damaging	Het
Olfr1009	T	A	2: 85,721,474 (GRCm38)	L23Q	probably damaging	Het
Olfr1200	G	A	2: 88,767,964 (GRCm38)	A117V	probably damaging	Het
Olfr1362	C	T	13: 21,611,127 (GRCm38)	V281M	possibly damaging	Het
Olfr821	T	G	10: 130,034,214 (GRCm38)	M196R	possibly damaging	Het
Ostm1	C	T	10: 42,683,272 (GRCm38)	A176V	probably null	Het
Pabpc6	C	A	17: 9,668,428 (GRCm38)	S398I	possibly damaging	Het
Pcdhac2	C	A	18: 37,144,186 (GRCm38)	P73H	possibly damaging	Het
Pcdhga9	A	G	18: 37,739,131 (GRCm38)	D671G	possibly damaging	Het
Peg10	GC	GCTCC	6: 4,756,452 (GRCm38)		probably benign	Het
Pigu	A	C	2: 155,301,240 (GRCm38)	L248R	possibly damaging	Het
Pinx1	C	A	14: 63,860,385 (GRCm38)		probably null	Het
Pon3	T	C	6: 5,221,664 (GRCm38)	N322S	possibly damaging	Het
Rnft1	A	G	11: 86,491,760 (GRCm38)	I270V	probably benign	Het
Scgb2b11	A	G	7: 32,210,581 (GRCm38)	F27L	probably damaging	Het
Slc5a4b	C	T	10: 76,075,109 (GRCm38)	V298I	probably damaging	Het
Slco1a6	T	A	6: 142,103,019 (GRCm38)	H345L	probably benign	Het
Sox1	C	T	8: 12,397,405 (GRCm38)	P349S	possibly damaging	Het
Spata31	A	G	13: 64,921,099 (GRCm38)	N354D	probably benign	Het
Speg	T	C	1: 75,406,770 (GRCm38)		probably null	Het
Stpg1	T	C	4: 135,533,722 (GRCm38)	I281T	probably benign	Het
Sult3a1	T	C	10: 33,877,287 (GRCm38)	L193P	probably damaging	Het
Tfap2a	A	G	13: 40,730,047 (GRCm38)	S7P	probably benign	Het
Tlr1	T	C	5: 64,925,678 (GRCm38)	I519V	probably benign	Het
Tmem238	A	G	7: 4,789,073 (GRCm38)	V157A	possibly damaging	Het
Tmem45b	A	T	9: 31,434,484 (GRCm38)		probably null	Het
Togaram2	A	T	17: 71,714,766 (GRCm38)	H742L	probably benign	Het
Trpc7	A	T	13: 56,789,674 (GRCm38)	Y656*	probably null	Het
Wdr35	T	A	12: 9,022,785 (GRCm38)	Y920N	probably damaging	Het
Xab2	G	A	8: 3,618,117 (GRCm38)	R154C	possibly damaging	Het
Zfp759	A	T	13: 67,140,113 (GRCm38)	H576L	possibly damaging	Het
Zfp958	G	T	8: 4,628,481 (GRCm38)	A169S	probably benign	Het

Other mutations in Tenm3

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00272:Tenm3	APN	8	48,417,060 (GRCm38)	missense	probably damaging	1.00
IGL00538:Tenm3	APN	8	48,236,025 (GRCm38)	missense	probably damaging	1.00
IGL00719:Tenm3	APN	8	48,279,042 (GRCm38)	missense	probably benign	0.39
IGL00720:Tenm3	APN	8	48,276,421 (GRCm38)	missense	probably damaging	0.98
IGL00870:Tenm3	APN	8	48,417,132 (GRCm38)	missense	probably benign	0.00
IGL00976:Tenm3	APN	8	48,256,841 (GRCm38)	missense	probably benign	0.14
IGL01469:Tenm3	APN	8	48,236,423 (GRCm38)	missense	probably damaging	1.00
IGL01508:Tenm3	APN	8	48,276,645 (GRCm38)	missense	probably benign	0.09
IGL01590:Tenm3	APN	8	48,228,802 (GRCm38)	missense	probably damaging	1.00
IGL01610:Tenm3	APN	8	48,254,477 (GRCm38)	missense	probably damaging	1.00
IGL01874:Tenm3	APN	8	48,236,758 (GRCm38)	nonsense	probably null
IGL01892:Tenm3	APN	8	48,276,396 (GRCm38)	missense	probably benign	0.09
IGL02098:Tenm3	APN	8	48,276,576 (GRCm38)	missense	possibly damaging	0.94
IGL02382:Tenm3	APN	8	48,235,476 (GRCm38)	missense	probably damaging	1.00
IGL02397:Tenm3	APN	8	48,236,694 (GRCm38)	missense	possibly damaging	0.94
IGL02475:Tenm3	APN	8	48,279,198 (GRCm38)	splice site	probably benign
IGL02502:Tenm3	APN	8	48,288,016 (GRCm38)	missense	probably damaging	1.00
IGL02508:Tenm3	APN	8	48,299,639 (GRCm38)	missense	probably benign	0.30
IGL02543:Tenm3	APN	8	48,298,956 (GRCm38)	missense	probably damaging	1.00
IGL02723:Tenm3	APN	8	48,276,903 (GRCm38)	missense	probably benign	0.02
IGL03037:Tenm3	APN	8	48,298,878 (GRCm38)	missense	possibly damaging	0.90
IGL03160:Tenm3	APN	8	48,646,418 (GRCm38)	missense	probably benign	0.05
IGL03268:Tenm3	APN	8	48,235,523 (GRCm38)	missense	probably damaging	1.00
IGL02988:Tenm3	UTSW	8	48,235,346 (GRCm38)	missense	probably damaging	0.99
PIT4431001:Tenm3	UTSW	8	48,235,607 (GRCm38)	missense	probably damaging	1.00
PIT4504001:Tenm3	UTSW	8	48,293,657 (GRCm38)	missense	probably damaging	1.00
R0079:Tenm3	UTSW	8	48,343,345 (GRCm38)	missense	possibly damaging	0.90
R0121:Tenm3	UTSW	8	48,342,659 (GRCm38)	missense	probably damaging	0.99
R0123:Tenm3	UTSW	8	48,674,472 (GRCm38)	missense	probably damaging	1.00
R0134:Tenm3	UTSW	8	48,674,472 (GRCm38)	missense	probably damaging	1.00
R0147:Tenm3	UTSW	8	48,236,720 (GRCm38)	missense	probably damaging	1.00
R0148:Tenm3	UTSW	8	48,236,720 (GRCm38)	missense	probably damaging	1.00
R0309:Tenm3	UTSW	8	48,341,034 (GRCm38)	missense	probably damaging	1.00
R0322:Tenm3	UTSW	8	48,236,912 (GRCm38)	splice site	probably benign
R0335:Tenm3	UTSW	8	48,232,105 (GRCm38)	missense	probably damaging	1.00
R0355:Tenm3	UTSW	8	48,228,975 (GRCm38)	missense	probably damaging	1.00
R0411:Tenm3	UTSW	8	48,287,791 (GRCm38)	missense	possibly damaging	0.61
R0505:Tenm3	UTSW	8	48,341,160 (GRCm38)	splice site	probably benign
R0573:Tenm3	UTSW	8	48,674,399 (GRCm38)	splice site	probably benign
R0599:Tenm3	UTSW	8	48,277,710 (GRCm38)	missense	probably damaging	1.00
R0616:Tenm3	UTSW	8	48,276,156 (GRCm38)	missense	possibly damaging	0.76
R0637:Tenm3	UTSW	8	48,236,525 (GRCm38)	missense	probably damaging	1.00
R0726:Tenm3	UTSW	8	48,236,594 (GRCm38)	missense	probably damaging	1.00
R0840:Tenm3	UTSW	8	48,335,742 (GRCm38)	missense	probably damaging	0.99
R0981:Tenm3	UTSW	8	48,298,965 (GRCm38)	missense	probably damaging	1.00
R1006:Tenm3	UTSW	8	48,228,542 (GRCm38)	missense	probably damaging	1.00
R1199:Tenm3	UTSW	8	48,235,582 (GRCm38)	missense	probably damaging	0.99
R1223:Tenm3	UTSW	8	48,240,396 (GRCm38)	missense	possibly damaging	0.72
R1240:Tenm3	UTSW	8	48,287,893 (GRCm38)	missense	possibly damaging	0.74
R1394:Tenm3	UTSW	8	48,276,400 (GRCm38)	missense	probably benign
R1455:Tenm3	UTSW	8	48,279,048 (GRCm38)	missense	possibly damaging	0.87
R1459:Tenm3	UTSW	8	48,235,971 (GRCm38)	missense	probably damaging	1.00
R1473:Tenm3	UTSW	8	48,310,625 (GRCm38)	missense	probably damaging	1.00
R1501:Tenm3	UTSW	8	48,343,316 (GRCm38)	missense	probably damaging	0.99
R1507:Tenm3	UTSW	8	48,287,822 (GRCm38)	missense	probably benign	0.01
R1522:Tenm3	UTSW	8	48,395,576 (GRCm38)	missense	probably damaging	1.00
R1524:Tenm3	UTSW	8	48,228,981 (GRCm38)	missense	possibly damaging	0.92
R1553:Tenm3	UTSW	8	48,236,421 (GRCm38)	missense	probably damaging	1.00
R1572:Tenm3	UTSW	8	48,228,993 (GRCm38)	missense	possibly damaging	0.94
R1583:Tenm3	UTSW	8	48,279,074 (GRCm38)	missense	probably benign	0.09
R1676:Tenm3	UTSW	8	48,417,119 (GRCm38)	missense	possibly damaging	0.83
R1732:Tenm3	UTSW	8	48,310,634 (GRCm38)	missense	probably damaging	1.00
R1768:Tenm3	UTSW	8	48,232,104 (GRCm38)	missense	probably damaging	1.00
R1777:Tenm3	UTSW	8	48,417,179 (GRCm38)	missense	probably benign	0.05
R1793:Tenm3	UTSW	8	48,674,544 (GRCm38)	missense	probably damaging	0.98
R1801:Tenm3	UTSW	8	48,276,256 (GRCm38)	missense	probably benign	0.39
R1863:Tenm3	UTSW	8	48,276,346 (GRCm38)	missense	probably benign	0.20
R1898:Tenm3	UTSW	8	48,310,761 (GRCm38)	missense	probably damaging	1.00
R1971:Tenm3	UTSW	8	48,236,313 (GRCm38)	missense	probably damaging	1.00
R1972:Tenm3	UTSW	8	48,228,591 (GRCm38)	missense	probably damaging	1.00
R1996:Tenm3	UTSW	8	48,228,668 (GRCm38)	missense	probably damaging	1.00
R2061:Tenm3	UTSW	8	48,342,256 (GRCm38)	critical splice donor site	probably null
R2109:Tenm3	UTSW	8	48,343,349 (GRCm38)	missense	possibly damaging	0.94
R2124:Tenm3	UTSW	8	48,417,006 (GRCm38)	critical splice donor site	probably null
R2190:Tenm3	UTSW	8	48,395,544 (GRCm38)	missense	probably damaging	1.00
R2204:Tenm3	UTSW	8	48,674,550 (GRCm38)	missense	probably benign	0.17
R2233:Tenm3	UTSW	8	48,276,169 (GRCm38)	missense	probably benign	0.04
R2234:Tenm3	UTSW	8	48,276,169 (GRCm38)	missense	probably benign	0.04
R2235:Tenm3	UTSW	8	48,276,169 (GRCm38)	missense	probably benign	0.04
R2237:Tenm3	UTSW	8	48,342,337 (GRCm38)	missense	probably damaging	1.00
R2418:Tenm3	UTSW	8	48,276,658 (GRCm38)	missense	possibly damaging	0.87
R2419:Tenm3	UTSW	8	48,276,658 (GRCm38)	missense	possibly damaging	0.87
R2435:Tenm3	UTSW	8	48,287,953 (GRCm38)	missense	probably damaging	1.00
R2483:Tenm3	UTSW	8	48,240,270 (GRCm38)	missense	probably damaging	0.99
R3406:Tenm3	UTSW	8	48,228,555 (GRCm38)	missense	probably damaging	1.00
R3724:Tenm3	UTSW	8	48,277,746 (GRCm38)	missense	probably damaging	0.97
R4009:Tenm3	UTSW	8	48,349,223 (GRCm38)	missense	probably damaging	1.00
R4210:Tenm3	UTSW	8	48,349,404 (GRCm38)	missense	probably damaging	1.00
R4293:Tenm3	UTSW	8	48,395,658 (GRCm38)	missense	probably damaging	1.00
R4656:Tenm3	UTSW	8	48,293,726 (GRCm38)	missense	probably damaging	1.00
R4663:Tenm3	UTSW	8	48,235,970 (GRCm38)	missense	probably damaging	1.00
R4835:Tenm3	UTSW	8	48,313,236 (GRCm38)	critical splice donor site	probably null
R4851:Tenm3	UTSW	8	48,310,621 (GRCm38)	critical splice donor site	probably null
R4867:Tenm3	UTSW	8	48,235,821 (GRCm38)	missense	probably damaging	1.00
R4892:Tenm3	UTSW	8	48,276,861 (GRCm38)	missense	probably damaging	0.99
R4895:Tenm3	UTSW	8	48,300,971 (GRCm38)	missense	probably damaging	1.00
R4962:Tenm3	UTSW	8	48,278,961 (GRCm38)	nonsense	probably null
R4995:Tenm3	UTSW	8	48,229,137 (GRCm38)	missense	possibly damaging	0.87
R4996:Tenm3	UTSW	8	48,235,826 (GRCm38)	missense	probably damaging	0.97
R5091:Tenm3	UTSW	8	48,342,308 (GRCm38)	missense	probably benign	0.14
R5228:Tenm3	UTSW	8	48,236,355 (GRCm38)	missense	probably damaging	1.00
R5253:Tenm3	UTSW	8	48,229,198 (GRCm38)	missense	possibly damaging	0.92
R5260:Tenm3	UTSW	8	48,236,855 (GRCm38)	missense	probably damaging	1.00
R5363:Tenm3	UTSW	8	48,287,831 (GRCm38)	missense	possibly damaging	0.55
R5414:Tenm3	UTSW	8	48,236,355 (GRCm38)	missense	probably damaging	1.00
R5427:Tenm3	UTSW	8	48,236,564 (GRCm38)	missense	probably damaging	1.00
R5431:Tenm3	UTSW	8	48,367,377 (GRCm38)	nonsense	probably null
R5566:Tenm3	UTSW	8	48,279,006 (GRCm38)	missense	probably damaging	1.00
R5579:Tenm3	UTSW	8	48,236,764 (GRCm38)	missense	probably damaging	1.00
R5656:Tenm3	UTSW	8	48,228,762 (GRCm38)	missense	probably damaging	1.00
R5931:Tenm3	UTSW	8	48,646,498 (GRCm38)	missense	probably benign	0.00
R5959:Tenm3	UTSW	8	48,646,447 (GRCm38)	nonsense	probably null
R5965:Tenm3	UTSW	8	48,228,508 (GRCm38)	nonsense	probably null
R6062:Tenm3	UTSW	8	48,343,406 (GRCm38)	missense	possibly damaging	0.46
R6151:Tenm3	UTSW	8	48,395,573 (GRCm38)	missense	probably damaging	1.00
R6157:Tenm3	UTSW	8	48,298,808 (GRCm38)	missense	probably damaging	0.96
R6167:Tenm3	UTSW	8	48,254,622 (GRCm38)	missense	possibly damaging	0.46
R6217:Tenm3	UTSW	8	48,293,665 (GRCm38)	missense	probably damaging	0.99
R6233:Tenm3	UTSW	8	48,417,059 (GRCm38)	missense	probably damaging	1.00
R6270:Tenm3	UTSW	8	48,367,394 (GRCm38)	missense	probably damaging	0.98
R6329:Tenm3	UTSW	8	48,276,849 (GRCm38)	missense	probably damaging	0.99
R6466:Tenm3	UTSW	8	48,236,063 (GRCm38)	missense	probably damaging	0.97
R6515:Tenm3	UTSW	8	48,417,222 (GRCm38)	missense	probably benign
R6516:Tenm3	UTSW	8	48,417,222 (GRCm38)	missense	probably benign
R6747:Tenm3	UTSW	8	48,343,243 (GRCm38)	missense	probably damaging	1.00
R6782:Tenm3	UTSW	8	48,646,256 (GRCm38)	critical splice donor site	probably null
R6788:Tenm3	UTSW	8	48,674,493 (GRCm38)	missense	probably damaging	1.00
R6823:Tenm3	UTSW	8	48,256,837 (GRCm38)	missense	probably damaging	0.99
R6846:Tenm3	UTSW	8	48,276,738 (GRCm38)	missense	probably benign	0.39
R6913:Tenm3	UTSW	8	48,298,937 (GRCm38)	missense	probably damaging	0.99
R6941:Tenm3	UTSW	8	48,674,416 (GRCm38)	missense	probably damaging	0.99
R6950:Tenm3	UTSW	8	48,240,479 (GRCm38)	nonsense	probably null
R6968:Tenm3	UTSW	8	48,236,439 (GRCm38)	missense	probably damaging	1.00
R6970:Tenm3	UTSW	8	48,236,439 (GRCm38)	missense	probably damaging	1.00
R6993:Tenm3	UTSW	8	48,236,439 (GRCm38)	missense	probably damaging	1.00
R7003:Tenm3	UTSW	8	48,240,444 (GRCm38)	missense	probably damaging	1.00
R7125:Tenm3	UTSW	8	48,674,553 (GRCm38)	missense	probably benign	0.00
R7222:Tenm3	UTSW	8	48,300,969 (GRCm38)	missense	probably damaging	1.00
R7232:Tenm3	UTSW	8	48,235,935 (GRCm38)	missense	probably damaging	1.00
R7336:Tenm3	UTSW	8	48,236,177 (GRCm38)	missense	possibly damaging	0.93
R7417:Tenm3	UTSW	8	48,236,183 (GRCm38)	missense	probably damaging	1.00
R7526:Tenm3	UTSW	8	48,287,812 (GRCm38)	missense	probably damaging	0.96
R7527:Tenm3	UTSW	8	48,276,600 (GRCm38)	missense	possibly damaging	0.60
R7616:Tenm3	UTSW	8	48,341,049 (GRCm38)	missense	possibly damaging	0.56
R7662:Tenm3	UTSW	8	48,335,727 (GRCm38)	missense	probably benign	0.27
R7734:Tenm3	UTSW	8	48,646,333 (GRCm38)	missense	probably damaging	1.00
R7802:Tenm3	UTSW	8	48,236,465 (GRCm38)	missense	probably damaging	1.00
R7812:Tenm3	UTSW	8	48,276,300 (GRCm38)	missense	probably benign	0.01
R7843:Tenm3	UTSW	8	48,229,111 (GRCm38)	nonsense	probably null
R7951:Tenm3	UTSW	8	48,310,703 (GRCm38)	missense	possibly damaging	0.86
R8293:Tenm3	UTSW	8	48,367,422 (GRCm38)	missense	possibly damaging	0.91
R8336:Tenm3	UTSW	8	48,293,773 (GRCm38)	missense	probably damaging	1.00
R8351:Tenm3	UTSW	8	48,287,872 (GRCm38)	missense	probably damaging	0.96
R8387:Tenm3	UTSW	8	48,287,848 (GRCm38)	missense	probably damaging	0.98
R8414:Tenm3	UTSW	8	48,293,509 (GRCm38)	missense	probably damaging	1.00
R8451:Tenm3	UTSW	8	48,287,872 (GRCm38)	missense	probably damaging	0.96
R8465:Tenm3	UTSW	8	48,229,181 (GRCm38)	missense	probably damaging	1.00
R8528:Tenm3	UTSW	8	48,342,633 (GRCm38)	missense	probably damaging	1.00
R8717:Tenm3	UTSW	8	48,299,645 (GRCm38)	missense	possibly damaging	0.77
R8734:Tenm3	UTSW	8	48,349,356 (GRCm38)	missense	probably benign	0.16
R8781:Tenm3	UTSW	8	48,342,449 (GRCm38)	frame shift	probably null
R8820:Tenm3	UTSW	8	48,310,724 (GRCm38)	missense	probably damaging	0.96
R8821:Tenm3	UTSW	8	48,276,382 (GRCm38)	missense
R8831:Tenm3	UTSW	8	48,276,382 (GRCm38)	missense
R8853:Tenm3	UTSW	8	48,342,347 (GRCm38)	missense	probably damaging	1.00
R8900:Tenm3	UTSW	8	48,236,402 (GRCm38)	missense	probably damaging	1.00
R8931:Tenm3	UTSW	8	48,235,602 (GRCm38)	missense	probably damaging	1.00
R8933:Tenm3	UTSW	8	48,279,060 (GRCm38)	missense	possibly damaging	0.53
R8989:Tenm3	UTSW	8	48,235,348 (GRCm38)	nonsense	probably null
R8998:Tenm3	UTSW	8	48,276,687 (GRCm38)	missense	probably damaging	1.00
R9008:Tenm3	UTSW	8	48,342,653 (GRCm38)	missense	probably damaging	0.98
R9017:Tenm3	UTSW	8	48,254,633 (GRCm38)	missense	probably damaging	0.99
R9101:Tenm3	UTSW	8	48,292,151 (GRCm38)	missense	probably damaging	1.00
R9108:Tenm3	UTSW	8	48,313,236 (GRCm38)	critical splice donor site	probably null
R9142:Tenm3	UTSW	8	48,335,513 (GRCm38)	missense	unknown
R9231:Tenm3	UTSW	8	48,236,196 (GRCm38)	missense	probably damaging	1.00
R9309:Tenm3	UTSW	8	48,298,937 (GRCm38)	missense	probably damaging	0.99
R9310:Tenm3	UTSW	8	48,555,900 (GRCm38)	unclassified	probably benign
R9336:Tenm3	UTSW	8	48,417,080 (GRCm38)	missense	probably damaging	1.00
R9373:Tenm3	UTSW	8	48,299,655 (GRCm38)	missense	probably damaging	1.00
R9393:Tenm3	UTSW	8	48,674,524 (GRCm38)	missense	probably damaging	0.99
R9509:Tenm3	UTSW	8	48,313,257 (GRCm38)	nonsense	probably null
R9575:Tenm3	UTSW	8	48,235,761 (GRCm38)	missense	possibly damaging	0.94
R9698:Tenm3	UTSW	8	48,236,211 (GRCm38)	missense	probably damaging	1.00
R9722:Tenm3	UTSW	8	48,300,814 (GRCm38)	missense	probably benign	0.00
R9788:Tenm3	UTSW	8	48,335,561 (GRCm38)	missense	probably benign	0.02
X0010:Tenm3	UTSW	8	48,287,829 (GRCm38)	missense	probably damaging	0.98
X0025:Tenm3	UTSW	8	48,236,477 (GRCm38)	missense	probably damaging	1.00
Z1177:Tenm3	UTSW	8	48,276,780 (GRCm38)	missense	probably damaging	1.00

Predicted Primers

PCR Primer
(F):5'- TGTGGTAGCATCATCAGAGGG -3'
(R):5'- GTGGGCTTGATGTCTATTAAATCAG -3'

Sequencing Primer
(F):5'- TAGCATCATCAGAGGGAGGAC -3'
(R):5'- TCCCATATGCTCAAATCTCCATAC -3'

Posted On

2019-05-15