Mutagenetix > Incidental Mutation

Incidental Mutation 'R7153:Dnah7b'

554225

Institutional Source

Beutler Lab

Gene Symbol

Dnah7b

Ensembl Gene

ENSMUSG00000041144

Gene Name

dynein, axonemal, heavy chain 7B

Synonyms

Dnahc7b, LOC227058

MMRRC Submission

045255-MU

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.118) question?

Stock #

R7153 (G1)

Quality Score

225.009

Status

Validated

Chromosome

Chromosomal Location

46066315-46373546 bp(+) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

T to A at 46126804 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Phenylalanine to Tyrosine at position 543 (F543Y)

Ref Sequence

ENSEMBL: ENSMUSP00000068738 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000069293]

AlphaFold

no structure available at present

Predicted Effect

probably benign
Transcript: ENSMUST00000069293
AA Change: F543Y

PolyPhen 2 Score 0.045 (Sensitivity: 0.94; Specificity: 0.83)

SMART Domains

Protein: ENSMUSP00000068738
Gene: ENSMUSG00000041144
AA Change: F543Y

Domain	Start	End	E-Value	Type
coiled coil region	760	790	N/A	INTRINSIC
Pfam:DHC_N2	800	1209	3.7e-150	PFAM
AAA	1364	1503	3.24e-1	SMART
AAA	2012	2160	5.39e-2	SMART
Pfam:AAA_8	2347	2618	2.4e-75	PFAM
Pfam:MT	2630	2979	2.6e-54	PFAM
Pfam:AAA_9	3001	3226	2.3e-98	PFAM
Pfam:Dynein_heavy	3362	4064	8.4e-288	PFAM

Meta Mutation Damage Score

0.0868

Coding Region Coverage

1x: 100.0%
3x: 99.9%
10x: 99.6%
20x: 98.8%

Validation Efficiency

100% (75/75)

Allele List at MGI

Other mutations in this stock

Total: 75 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Ano2	A	G	6: 125,992,943 (GRCm38)	T741A	possibly damaging	Het
Aox4	T	C	1: 58,250,219 (GRCm38)	M767T	probably damaging	Het
Arhgap39	C	A	15: 76,765,491 (GRCm38)	S27I	probably benign	Het
AU018091	T	A	7: 3,159,513 (GRCm38)	M296L	probably benign	Het
Axin1	A	G	17: 26,187,968 (GRCm38)	T512A	probably benign	Het
B4galnt3	A	T	6: 120,214,968 (GRCm38)	D602E	probably benign	Het
Bcl6	G	A	16: 23,966,226 (GRCm38)	R675*	probably null	Het
Bsnd	A	T	4: 106,492,033 (GRCm38)	D3E	probably benign	Het
Btbd18	C	T	2: 84,666,428 (GRCm38)	R137*	probably null	Het
C2cd5	A	G	6: 143,019,409 (GRCm38)	S871P	probably benign	Het
Cobl	G	T	11: 12,254,128 (GRCm38)	P858Q	probably damaging	Het
Col6a1	C	T	10: 76,710,341 (GRCm38)		probably null	Het
Crb2	A	T	2: 37,787,408 (GRCm38)	H304L	probably benign	Het
Crybg1	T	A	10: 43,964,666 (GRCm38)	Y1812F	possibly damaging	Het
Ddx60	A	T	8: 61,988,108 (GRCm38)	K1070N	possibly damaging	Het
Defb22	T	C	2: 152,485,920 (GRCm38)	K115R	unknown	Het
Dhx8	C	T	11: 101,740,175 (GRCm38)		probably null	Het
Dnah5	T	A	15: 28,365,522 (GRCm38)		probably null	Het
Ehhadh	A	G	16: 21,766,321 (GRCm38)	F270S	probably damaging	Het
Esyt2	A	G	12: 116,346,508 (GRCm38)	M397V	probably benign	Het
Fanca	A	T	8: 123,316,425 (GRCm38)	L74H	probably damaging	Het
Fbxl17	C	A	17: 63,060,351 (GRCm38)	V676F	probably benign	Het
Fndc1	A	G	17: 7,801,645 (GRCm38)	V102A	probably damaging	Het
Gpalpp1	T	C	14: 76,095,011 (GRCm38)	Y273C	probably damaging	Het
Gpatch8	TTCCTCCTCCTCCTCTTCCTCCTCCTC	TTCCTCCTCCTCCTCCTCTTCCTCCTCCTC	11: 102,480,188 (GRCm38)		probably benign	Het
Grik2	T	C	10: 49,535,367 (GRCm38)	H225R	probably benign	Het
Helz2	A	T	2: 181,231,285 (GRCm38)	S2411T	probably benign	Het
Hnmt	C	T	2: 24,014,341 (GRCm38)	A103T	probably damaging	Het
Ighv15-2	G	T	12: 114,564,590 (GRCm38)	Y114*	probably null	Het
Irak2	A	G	6: 113,678,709 (GRCm38)	H357R	probably benign	Het
Kcp	T	C	6: 29,499,015 (GRCm38)	E320G	probably damaging	Het
Kpna4	A	G	3: 69,089,798 (GRCm38)	L352S	probably damaging	Het
Krt36	G	A	11: 100,105,146 (GRCm38)	Q151*	probably null	Het
Krt77	G	A	15: 101,865,496 (GRCm38)	T241M	probably benign	Het
Lca5l	T	A	16: 96,173,809 (GRCm38)	N305I	probably damaging	Het
Lefty1	T	A	1: 180,937,767 (GRCm38)	L300Q	probably benign	Het
Mertk	A	G	2: 128,736,649 (GRCm38)	Y185C	probably damaging	Het
Mmp14	T	C	14: 54,436,251 (GRCm38)	I124T	possibly damaging	Het
Nlrc4	T	C	17: 74,447,103 (GRCm38)	E95G	possibly damaging	Het
Npc1	A	G	18: 12,213,291 (GRCm38)	F283L	possibly damaging	Het
Olfr1180	A	C	2: 88,412,118 (GRCm38)	L180W	probably damaging	Het
Olfr1282	A	T	2: 111,335,901 (GRCm38)	M59K	probably damaging	Het
Pcdha11	T	C	18: 37,011,225 (GRCm38)	V123A	probably damaging	Het
Pcdhga2	T	C	18: 37,669,208 (GRCm38)	V35A	probably damaging	Het
Pgd	G	T	4: 149,161,678 (GRCm38)	T94K	probably benign	Het
Pik3c2a	T	C	7: 116,342,252 (GRCm38)	N1593S	probably damaging	Het
Pkd1l3	GACACCTGCATCCAGCAGCCCAACAAACATGACATCAGACACACCTGCATCCAGCAGCCCAACAAACATGACATCAGACACACCTGCATCCAGCAGCCCAACAAACATGACATCAGACACACCTGCATCCAGCAGCCCA	GACACCTGCATCCAGCAGCCCAACAAACATGACATCAGACACACCTGCATCCAGCAGCCCAACAAACATGACATCAGACACACCTGCATCCAGCAGCCCA	8: 109,624,195 (GRCm38)		probably benign	Het
Plcb3	A	G	19: 6,958,084 (GRCm38)		probably null	Het
Prkd3	C	T	17: 78,966,355 (GRCm38)	D491N	probably benign	Het
Ptprf	T	C	4: 118,231,543 (GRCm38)	T688A	probably damaging	Het
Pycr2	T	A	1: 180,906,682 (GRCm38)	L210M	probably damaging	Het
Rpl36	T	C	17: 56,614,137 (GRCm38)	I81T	probably benign	Het
Rraga	C	T	4: 86,576,016 (GRCm38)	A33V	probably damaging	Het
Slc29a1	G	A	17: 45,585,762 (GRCm38)	A429V	probably damaging	Het
Stab1	T	G	14: 31,160,584 (GRCm38)	E432A	probably benign	Het
Synj1	C	T	16: 90,948,090 (GRCm38)	G1189R	probably benign	Het
Synpo2	A	G	3: 123,112,404 (GRCm38)	*1088Q	probably null	Het
Tbc1d21	T	C	9: 58,363,093 (GRCm38)	D133G	probably damaging	Het
Tenm2	A	G	11: 36,024,182 (GRCm38)	V2176A	probably damaging	Het
Tff1	A	G	17: 31,162,798 (GRCm38)	I35T	probably benign	Het
Thnsl1	T	C	2: 21,212,953 (GRCm38)	V506A	possibly damaging	Het
Timm10b	A	G	7: 105,640,880 (GRCm38)	Q50R	unknown	Het
Tjp2	A	T	19: 24,101,981 (GRCm38)	N843K	probably benign	Het
Tle1	A	T	4: 72,139,061 (GRCm38)	F101I	probably benign	Het
Tmem225	T	C	9: 40,148,368 (GRCm38)	F15L	probably benign	Het
Trav12-3	T	C	14: 53,622,161 (GRCm38)	L88P	probably benign	Het
Ttc7b	A	T	12: 100,355,034 (GRCm38)	W613R	probably damaging	Het
Ttn	T	C	2: 76,945,316 (GRCm38)	D1840G	unknown	Het
Ttn	T	A	2: 76,778,504 (GRCm38)	M17723L	probably benign	Het
Tubgcp2	T	C	7: 140,001,036 (GRCm38)	H668R	probably benign	Het
Ush2a	C	A	1: 188,728,484 (GRCm38)	N2647K	possibly damaging	Het
Vmn1r14	C	T	6: 57,233,866 (GRCm38)	S143F	probably benign	Het
Vmn2r70	A	G	7: 85,565,054 (GRCm38)	S297P	probably damaging	Het
Ywhab	T	C	2: 164,014,060 (GRCm38)	F119L	probably damaging	Het
Zmym2	T	A	14: 56,950,202 (GRCm38)	D1108E	probably benign	Het

Other mutations in Dnah7b

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00336:Dnah7b	APN	1	46,142,149 (GRCm38)	missense	probably benign	0.04
IGL00796:Dnah7b	APN	1	46,211,337 (GRCm38)	missense	probably damaging	0.96
IGL00825:Dnah7b	APN	1	46,224,651 (GRCm38)	missense	probably damaging	1.00
IGL00910:Dnah7b	APN	1	46,066,729 (GRCm38)	unclassified	probably benign
IGL00950:Dnah7b	APN	1	46,214,322 (GRCm38)	missense	probably benign	0.07
IGL01142:Dnah7b	APN	1	46,195,378 (GRCm38)	critical splice donor site	probably null
IGL01350:Dnah7b	APN	1	46,081,432 (GRCm38)	splice site	probably benign
IGL01392:Dnah7b	APN	1	46,126,788 (GRCm38)	missense	probably damaging	1.00
IGL01403:Dnah7b	APN	1	46,116,300 (GRCm38)	splice site	probably benign
IGL01460:Dnah7b	APN	1	46,139,704 (GRCm38)	missense	possibly damaging	0.82
IGL01576:Dnah7b	APN	1	46,268,653 (GRCm38)	missense	probably damaging	1.00
IGL01693:Dnah7b	APN	1	46,358,147 (GRCm38)	missense	probably benign	0.29
IGL01838:Dnah7b	APN	1	46,358,137 (GRCm38)	nonsense	probably null
IGL01906:Dnah7b	APN	1	46,175,453 (GRCm38)	missense	probably damaging	1.00
IGL01960:Dnah7b	APN	1	46,124,337 (GRCm38)	splice site	probably benign
IGL01989:Dnah7b	APN	1	46,289,534 (GRCm38)	missense	probably damaging	1.00
IGL02127:Dnah7b	APN	1	46,139,875 (GRCm38)	missense	probably benign
IGL02213:Dnah7b	APN	1	46,233,592 (GRCm38)	missense	probably damaging	0.97
IGL02267:Dnah7b	APN	1	46,226,930 (GRCm38)	missense	probably damaging	1.00
IGL02349:Dnah7b	APN	1	46,099,503 (GRCm38)	nonsense	probably null
IGL02381:Dnah7b	APN	1	46,277,120 (GRCm38)	missense	probably damaging	1.00
IGL02473:Dnah7b	APN	1	46,234,193 (GRCm38)	missense	probably damaging	1.00
IGL02484:Dnah7b	APN	1	46,195,318 (GRCm38)	missense	probably damaging	1.00
IGL02590:Dnah7b	APN	1	46,123,777 (GRCm38)	missense	probably benign	0.02
IGL02655:Dnah7b	APN	1	46,116,301 (GRCm38)	splice site	probably benign
IGL02704:Dnah7b	APN	1	46,142,133 (GRCm38)	missense	probably benign	0.03
IGL02719:Dnah7b	APN	1	46,099,608 (GRCm38)	splice site	probably benign
IGL02745:Dnah7b	APN	1	46,195,029 (GRCm38)	splice site	probably benign
IGL02818:Dnah7b	APN	1	46,290,808 (GRCm38)	missense	probably damaging	1.00
IGL02892:Dnah7b	APN	1	46,119,298 (GRCm38)	missense	possibly damaging	0.79
IGL03285:Dnah7b	APN	1	46,182,375 (GRCm38)	missense	probably benign	0.00
IGL03354:Dnah7b	APN	1	46,085,689 (GRCm38)	missense	probably damaging	1.00
IGL03355:Dnah7b	APN	1	46,119,304 (GRCm38)	missense	probably benign	0.18
BB001:Dnah7b	UTSW	1	46,219,430 (GRCm38)	missense	probably benign	0.04
BB011:Dnah7b	UTSW	1	46,219,430 (GRCm38)	missense	probably benign	0.04
PIT4305001:Dnah7b	UTSW	1	46,373,348 (GRCm38)	missense	probably damaging	1.00
R0116:Dnah7b	UTSW	1	46,213,360 (GRCm38)	missense	possibly damaging	0.94
R0145:Dnah7b	UTSW	1	46,223,178 (GRCm38)	missense	probably damaging	1.00
R0230:Dnah7b	UTSW	1	46,219,348 (GRCm38)	missense	probably damaging	1.00
R0302:Dnah7b	UTSW	1	46,123,777 (GRCm38)	missense	probably benign	0.26
R0313:Dnah7b	UTSW	1	46,207,643 (GRCm38)	missense	probably damaging	1.00
R0317:Dnah7b	UTSW	1	46,134,656 (GRCm38)	missense	probably damaging	1.00
R0347:Dnah7b	UTSW	1	46,240,944 (GRCm38)	missense	probably damaging	1.00
R0352:Dnah7b	UTSW	1	46,277,126 (GRCm38)	missense	probably damaging	0.98
R0363:Dnah7b	UTSW	1	46,236,788 (GRCm38)	missense	probably damaging	0.99
R0379:Dnah7b	UTSW	1	46,140,176 (GRCm38)	missense	probably benign	0.00
R0502:Dnah7b	UTSW	1	46,219,544 (GRCm38)	missense	probably damaging	0.96
R0602:Dnah7b	UTSW	1	46,324,842 (GRCm38)	missense	probably damaging	1.00
R0631:Dnah7b	UTSW	1	46,240,992 (GRCm38)	missense	probably benign	0.02
R0664:Dnah7b	UTSW	1	46,324,842 (GRCm38)	missense	probably damaging	1.00
R0882:Dnah7b	UTSW	1	46,340,132 (GRCm38)	missense	probably benign	0.00
R0931:Dnah7b	UTSW	1	46,099,612 (GRCm38)	splice site	probably benign
R1035:Dnah7b	UTSW	1	46,124,448 (GRCm38)	missense	probably benign
R1147:Dnah7b	UTSW	1	46,340,266 (GRCm38)	missense	probably damaging	0.99
R1147:Dnah7b	UTSW	1	46,340,266 (GRCm38)	missense	probably damaging	0.99
R1166:Dnah7b	UTSW	1	46,325,810 (GRCm38)	missense	probably damaging	1.00
R1219:Dnah7b	UTSW	1	46,340,120 (GRCm38)	missense	probably benign	0.00
R1318:Dnah7b	UTSW	1	46,099,509 (GRCm38)	missense	possibly damaging	0.80
R1334:Dnah7b	UTSW	1	46,322,335 (GRCm38)	missense	probably damaging	0.99
R1429:Dnah7b	UTSW	1	46,289,656 (GRCm38)	missense	possibly damaging	0.84
R1440:Dnah7b	UTSW	1	46,078,593 (GRCm38)	splice site	probably benign
R1484:Dnah7b	UTSW	1	46,137,543 (GRCm38)	missense	probably benign	0.00
R1529:Dnah7b	UTSW	1	46,177,281 (GRCm38)	missense	probably damaging	1.00
R1544:Dnah7b	UTSW	1	46,066,797 (GRCm38)	missense	unknown
R1607:Dnah7b	UTSW	1	46,290,646 (GRCm38)	missense	probably damaging	1.00
R1609:Dnah7b	UTSW	1	46,352,966 (GRCm38)	missense	probably damaging	1.00
R1652:Dnah7b	UTSW	1	46,175,390 (GRCm38)	nonsense	probably null
R1681:Dnah7b	UTSW	1	46,324,712 (GRCm38)	nonsense	probably null
R1716:Dnah7b	UTSW	1	46,191,783 (GRCm38)	missense	probably damaging	1.00
R1753:Dnah7b	UTSW	1	46,322,335 (GRCm38)	missense	probably damaging	0.99
R1834:Dnah7b	UTSW	1	46,233,759 (GRCm38)	missense	possibly damaging	0.90
R1838:Dnah7b	UTSW	1	46,277,105 (GRCm38)	missense	probably damaging	1.00
R1838:Dnah7b	UTSW	1	46,116,177 (GRCm38)	missense	probably benign	0.04
R1898:Dnah7b	UTSW	1	46,236,714 (GRCm38)	missense	probably benign	0.02
R1962:Dnah7b	UTSW	1	46,242,103 (GRCm38)	missense	possibly damaging	0.95
R2001:Dnah7b	UTSW	1	46,142,087 (GRCm38)	missense	possibly damaging	0.69
R2049:Dnah7b	UTSW	1	46,268,670 (GRCm38)	missense	probably damaging	1.00
R2076:Dnah7b	UTSW	1	46,242,321 (GRCm38)	nonsense	probably null
R2083:Dnah7b	UTSW	1	46,241,067 (GRCm38)	missense	possibly damaging	0.90
R2140:Dnah7b	UTSW	1	46,268,670 (GRCm38)	missense	probably damaging	1.00
R2141:Dnah7b	UTSW	1	46,268,670 (GRCm38)	missense	probably damaging	1.00
R2142:Dnah7b	UTSW	1	46,268,670 (GRCm38)	missense	probably damaging	1.00
R2165:Dnah7b	UTSW	1	46,097,992 (GRCm38)	splice site	probably benign
R2172:Dnah7b	UTSW	1	46,124,512 (GRCm38)	missense	probably benign	0.12
R2239:Dnah7b	UTSW	1	46,201,184 (GRCm38)	splice site	probably benign
R2247:Dnah7b	UTSW	1	46,277,063 (GRCm38)	missense	probably damaging	1.00
R2267:Dnah7b	UTSW	1	46,233,915 (GRCm38)	missense	probably damaging	1.00
R2405:Dnah7b	UTSW	1	46,362,954 (GRCm38)	missense	probably benign	0.31
R2509:Dnah7b	UTSW	1	46,195,287 (GRCm38)	missense	probably damaging	0.96
R2895:Dnah7b	UTSW	1	46,139,741 (GRCm38)	missense	probably damaging	1.00
R2965:Dnah7b	UTSW	1	46,207,572 (GRCm38)	missense	probably damaging	1.00
R3013:Dnah7b	UTSW	1	46,188,687 (GRCm38)	critical splice donor site	probably null
R3022:Dnah7b	UTSW	1	46,182,423 (GRCm38)	missense	probably damaging	0.99
R3056:Dnah7b	UTSW	1	46,268,709 (GRCm38)	missense	possibly damaging	0.95
R3107:Dnah7b	UTSW	1	46,352,873 (GRCm38)	missense	probably benign	0.00
R3735:Dnah7b	UTSW	1	46,299,875 (GRCm38)	missense	probably benign	0.05
R3898:Dnah7b	UTSW	1	46,243,257 (GRCm38)	missense	probably damaging	1.00
R3944:Dnah7b	UTSW	1	46,137,485 (GRCm38)	missense	probably damaging	1.00
R3983:Dnah7b	UTSW	1	46,233,711 (GRCm38)	missense	possibly damaging	0.88
R4041:Dnah7b	UTSW	1	46,081,495 (GRCm38)	missense	probably benign
R4172:Dnah7b	UTSW	1	46,226,946 (GRCm38)	missense	probably damaging	1.00
R4210:Dnah7b	UTSW	1	46,137,418 (GRCm38)	missense	possibly damaging	0.63
R4306:Dnah7b	UTSW	1	46,221,772 (GRCm38)	missense	probably damaging	0.99
R4391:Dnah7b	UTSW	1	46,337,594 (GRCm38)	splice site	probably null
R4414:Dnah7b	UTSW	1	46,126,680 (GRCm38)	missense	probably benign	0.00
R4495:Dnah7b	UTSW	1	46,085,632 (GRCm38)	missense	probably benign	0.00
R4660:Dnah7b	UTSW	1	46,289,536 (GRCm38)	missense	probably damaging	1.00
R4670:Dnah7b	UTSW	1	46,078,524 (GRCm38)	missense	probably damaging	1.00
R4675:Dnah7b	UTSW	1	46,217,157 (GRCm38)	missense	possibly damaging	0.89
R4685:Dnah7b	UTSW	1	46,211,328 (GRCm38)	missense	probably damaging	1.00
R4727:Dnah7b	UTSW	1	46,207,656 (GRCm38)	missense	probably damaging	1.00
R4735:Dnah7b	UTSW	1	46,066,955 (GRCm38)	missense	unknown
R4780:Dnah7b	UTSW	1	46,353,014 (GRCm38)	missense	probably benign
R4828:Dnah7b	UTSW	1	46,128,112 (GRCm38)	missense	possibly damaging	0.59
R4859:Dnah7b	UTSW	1	46,356,602 (GRCm38)	missense	probably damaging	1.00
R4865:Dnah7b	UTSW	1	46,195,074 (GRCm38)	missense	probably damaging	1.00
R4871:Dnah7b	UTSW	1	46,081,444 (GRCm38)	missense	probably benign	0.21
R4881:Dnah7b	UTSW	1	46,201,318 (GRCm38)	missense	probably damaging	1.00
R4902:Dnah7b	UTSW	1	46,290,775 (GRCm38)	missense	probably benign	0.04
R4960:Dnah7b	UTSW	1	46,233,726 (GRCm38)	missense	probably benign
R5000:Dnah7b	UTSW	1	46,099,503 (GRCm38)	nonsense	probably null
R5005:Dnah7b	UTSW	1	46,242,028 (GRCm38)	missense	probably damaging	0.99
R5026:Dnah7b	UTSW	1	46,187,363 (GRCm38)	missense	probably damaging	0.99
R5080:Dnah7b	UTSW	1	46,182,380 (GRCm38)	nonsense	probably null
R5174:Dnah7b	UTSW	1	46,243,349 (GRCm38)	missense	possibly damaging	0.83
R5178:Dnah7b	UTSW	1	46,358,216 (GRCm38)	missense	possibly damaging	0.50
R5244:Dnah7b	UTSW	1	46,233,858 (GRCm38)	missense	probably damaging	1.00
R5250:Dnah7b	UTSW	1	46,373,354 (GRCm38)	missense	probably damaging	1.00
R5350:Dnah7b	UTSW	1	46,233,689 (GRCm38)	missense	probably benign	0.16
R5380:Dnah7b	UTSW	1	46,217,191 (GRCm38)	missense	probably benign	0.18
R5387:Dnah7b	UTSW	1	46,188,659 (GRCm38)	missense	probably damaging	1.00
R5423:Dnah7b	UTSW	1	46,358,271 (GRCm38)	missense	probably benign	0.01
R5426:Dnah7b	UTSW	1	46,242,206 (GRCm38)	missense	possibly damaging	0.82
R5451:Dnah7b	UTSW	1	46,242,019 (GRCm38)	missense	possibly damaging	0.73
R5459:Dnah7b	UTSW	1	46,109,312 (GRCm38)	missense	probably null
R5479:Dnah7b	UTSW	1	46,223,105 (GRCm38)	missense	probably damaging	1.00
R5583:Dnah7b	UTSW	1	46,242,199 (GRCm38)	missense	probably benign	0.06
R5637:Dnah7b	UTSW	1	46,356,514 (GRCm38)	missense	possibly damaging	0.95
R5641:Dnah7b	UTSW	1	46,268,764 (GRCm38)	splice site	probably null
R5659:Dnah7b	UTSW	1	46,352,849 (GRCm38)	missense	probably damaging	1.00
R5739:Dnah7b	UTSW	1	46,233,992 (GRCm38)	missense	probably damaging	1.00
R5759:Dnah7b	UTSW	1	46,277,120 (GRCm38)	missense	probably damaging	1.00
R5821:Dnah7b	UTSW	1	46,142,132 (GRCm38)	missense	possibly damaging	0.91
R5874:Dnah7b	UTSW	1	46,191,725 (GRCm38)	missense	probably damaging	1.00
R5892:Dnah7b	UTSW	1	46,337,593 (GRCm38)	critical splice donor site	probably null
R5918:Dnah7b	UTSW	1	46,221,643 (GRCm38)	missense	probably benign
R5941:Dnah7b	UTSW	1	46,187,290 (GRCm38)	missense	probably damaging	1.00
R5965:Dnah7b	UTSW	1	46,362,987 (GRCm38)	missense	probably damaging	1.00
R5987:Dnah7b	UTSW	1	46,119,398 (GRCm38)	splice site	probably null
R6041:Dnah7b	UTSW	1	46,289,645 (GRCm38)	missense	probably benign	0.04
R6043:Dnah7b	UTSW	1	46,139,789 (GRCm38)	missense	probably benign
R6049:Dnah7b	UTSW	1	46,085,602 (GRCm38)	missense	probably benign
R6131:Dnah7b	UTSW	1	46,253,466 (GRCm38)	missense	probably damaging	1.00
R6168:Dnah7b	UTSW	1	46,290,703 (GRCm38)	missense	probably damaging	1.00
R6195:Dnah7b	UTSW	1	46,204,269 (GRCm38)	missense	probably damaging	1.00
R6219:Dnah7b	UTSW	1	46,233,585 (GRCm38)	missense	probably benign	0.03
R6226:Dnah7b	UTSW	1	46,126,668 (GRCm38)	missense	probably benign	0.01
R6233:Dnah7b	UTSW	1	46,204,269 (GRCm38)	missense	probably damaging	1.00
R6247:Dnah7b	UTSW	1	46,225,888 (GRCm38)	missense	probably benign
R6273:Dnah7b	UTSW	1	46,242,316 (GRCm38)	missense	possibly damaging	0.94
R6279:Dnah7b	UTSW	1	46,325,886 (GRCm38)	missense	probably damaging	1.00
R6300:Dnah7b	UTSW	1	46,325,886 (GRCm38)	missense	probably damaging	1.00
R6330:Dnah7b	UTSW	1	46,340,175 (GRCm38)	missense	probably damaging	1.00
R6476:Dnah7b	UTSW	1	46,242,204 (GRCm38)	nonsense	probably null
R6494:Dnah7b	UTSW	1	46,099,431 (GRCm38)	missense	probably damaging	1.00
R6762:Dnah7b	UTSW	1	46,224,742 (GRCm38)	missense	probably benign	0.12
R6800:Dnah7b	UTSW	1	46,340,217 (GRCm38)	missense	possibly damaging	0.90
R6838:Dnah7b	UTSW	1	46,191,788 (GRCm38)	missense	probably damaging	1.00
R6937:Dnah7b	UTSW	1	46,195,120 (GRCm38)	missense	probably damaging	1.00
R6940:Dnah7b	UTSW	1	46,119,268 (GRCm38)	missense	probably benign	0.12
R6969:Dnah7b	UTSW	1	46,358,238 (GRCm38)	missense	probably damaging	1.00
R6993:Dnah7b	UTSW	1	46,195,139 (GRCm38)	critical splice donor site	probably null
R7040:Dnah7b	UTSW	1	46,236,809 (GRCm38)	missense	probably benign	0.01
R7117:Dnah7b	UTSW	1	46,352,813 (GRCm38)	critical splice acceptor site	probably null
R7135:Dnah7b	UTSW	1	46,139,710 (GRCm38)	missense	probably damaging	0.99
R7189:Dnah7b	UTSW	1	46,242,142 (GRCm38)	missense	probably damaging	1.00
R7237:Dnah7b	UTSW	1	46,139,966 (GRCm38)	missense	probably damaging	0.98
R7243:Dnah7b	UTSW	1	46,083,754 (GRCm38)	missense	probably benign
R7244:Dnah7b	UTSW	1	46,277,143 (GRCm38)	missense	probably damaging	0.99
R7248:Dnah7b	UTSW	1	46,142,085 (GRCm38)	missense	possibly damaging	0.83
R7318:Dnah7b	UTSW	1	46,195,372 (GRCm38)	missense	probably damaging	1.00
R7375:Dnah7b	UTSW	1	46,303,634 (GRCm38)	missense	probably damaging	1.00
R7483:Dnah7b	UTSW	1	46,175,419 (GRCm38)	missense	probably damaging	1.00
R7486:Dnah7b	UTSW	1	46,290,734 (GRCm38)	missense	probably damaging	1.00
R7498:Dnah7b	UTSW	1	46,325,765 (GRCm38)	missense	probably damaging	1.00
R7501:Dnah7b	UTSW	1	46,356,554 (GRCm38)	missense	probably damaging	1.00
R7513:Dnah7b	UTSW	1	46,124,346 (GRCm38)	missense	probably benign	0.06
R7547:Dnah7b	UTSW	1	46,214,413 (GRCm38)	missense	possibly damaging	0.82
R7620:Dnah7b	UTSW	1	46,268,634 (GRCm38)	missense	probably damaging	1.00
R7670:Dnah7b	UTSW	1	46,109,302 (GRCm38)	missense	probably benign
R7676:Dnah7b	UTSW	1	46,234,164 (GRCm38)	nonsense	probably null
R7731:Dnah7b	UTSW	1	46,139,745 (GRCm38)	missense	probably benign	0.00
R7760:Dnah7b	UTSW	1	46,201,253 (GRCm38)	missense	probably damaging	1.00
R7768:Dnah7b	UTSW	1	46,137,474 (GRCm38)	missense	probably benign
R7807:Dnah7b	UTSW	1	46,214,367 (GRCm38)	missense	probably benign
R7895:Dnah7b	UTSW	1	46,249,950 (GRCm38)	missense	probably damaging	1.00
R7911:Dnah7b	UTSW	1	46,139,678 (GRCm38)	missense	probably damaging	1.00
R7924:Dnah7b	UTSW	1	46,219,430 (GRCm38)	missense	probably benign	0.04
R7944:Dnah7b	UTSW	1	46,227,003 (GRCm38)	missense	probably benign
R7946:Dnah7b	UTSW	1	46,233,579 (GRCm38)	missense	probably damaging	1.00
R7983:Dnah7b	UTSW	1	46,243,424 (GRCm38)	missense	probably damaging	1.00
R8012:Dnah7b	UTSW	1	46,243,365 (GRCm38)	missense	probably damaging	1.00
R8069:Dnah7b	UTSW	1	46,224,706 (GRCm38)	nonsense	probably null
R8094:Dnah7b	UTSW	1	46,126,804 (GRCm38)	missense	probably benign	0.01
R8137:Dnah7b	UTSW	1	46,233,753 (GRCm38)	missense	probably damaging	1.00
R8167:Dnah7b	UTSW	1	46,253,511 (GRCm38)	missense	possibly damaging	0.95
R8268:Dnah7b	UTSW	1	46,356,576 (GRCm38)	missense	probably benign	0.43
R8309:Dnah7b	UTSW	1	46,139,872 (GRCm38)	missense	probably damaging	1.00
R8313:Dnah7b	UTSW	1	46,175,296 (GRCm38)	missense	possibly damaging	0.81
R8410:Dnah7b	UTSW	1	46,356,659 (GRCm38)	critical splice donor site	probably null
R8438:Dnah7b	UTSW	1	46,188,679 (GRCm38)	missense	probably damaging	1.00
R8446:Dnah7b	UTSW	1	46,290,715 (GRCm38)	missense	probably damaging	1.00
R8471:Dnah7b	UTSW	1	46,099,490 (GRCm38)	missense	possibly damaging	0.92
R8551:Dnah7b	UTSW	1	46,116,200 (GRCm38)	missense	possibly damaging	0.94
R8711:Dnah7b	UTSW	1	46,175,438 (GRCm38)	missense	probably damaging	1.00
R8745:Dnah7b	UTSW	1	46,182,464 (GRCm38)	missense	possibly damaging	0.82
R8765:Dnah7b	UTSW	1	46,352,999 (GRCm38)	missense	possibly damaging	0.91
R8797:Dnah7b	UTSW	1	46,123,646 (GRCm38)	missense	probably damaging	1.00
R8805:Dnah7b	UTSW	1	46,234,145 (GRCm38)	missense	possibly damaging	0.90
R8830:Dnah7b	UTSW	1	46,191,793 (GRCm38)	missense	probably damaging	1.00
R8861:Dnah7b	UTSW	1	46,241,076 (GRCm38)	missense	possibly damaging	0.82
R8905:Dnah7b	UTSW	1	46,253,374 (GRCm38)	missense	probably damaging	0.99
R9009:Dnah7b	UTSW	1	46,223,072 (GRCm38)	missense	probably benign	0.00
R9058:Dnah7b	UTSW	1	46,243,415 (GRCm38)	missense	probably damaging	1.00
R9130:Dnah7b	UTSW	1	46,134,514 (GRCm38)	missense	probably benign	0.01
R9131:Dnah7b	UTSW	1	46,227,020 (GRCm38)	missense	probably damaging	1.00
R9181:Dnah7b	UTSW	1	46,142,034 (GRCm38)	missense	probably damaging	1.00
R9182:Dnah7b	UTSW	1	46,290,878 (GRCm38)	missense	probably benign	0.06
R9223:Dnah7b	UTSW	1	46,322,260 (GRCm38)	missense	probably benign	0.12
R9391:Dnah7b	UTSW	1	46,233,754 (GRCm38)	nonsense	probably null
R9392:Dnah7b	UTSW	1	46,123,738 (GRCm38)	nonsense	probably null
R9456:Dnah7b	UTSW	1	46,126,793 (GRCm38)	missense	possibly damaging	0.82
R9498:Dnah7b	UTSW	1	46,214,404 (GRCm38)	missense	probably benign	0.27
R9553:Dnah7b	UTSW	1	46,225,796 (GRCm38)	missense	probably damaging	0.99
R9598:Dnah7b	UTSW	1	46,253,461 (GRCm38)	missense	possibly damaging	0.67
R9653:Dnah7b	UTSW	1	46,213,384 (GRCm38)	missense	possibly damaging	0.55
R9781:Dnah7b	UTSW	1	46,337,594 (GRCm38)	splice site	probably null
RF020:Dnah7b	UTSW	1	46,373,261 (GRCm38)	missense	possibly damaging	0.84
V8831:Dnah7b	UTSW	1	46,373,298 (GRCm38)	nonsense	probably null
X0023:Dnah7b	UTSW	1	46,303,577 (GRCm38)	missense	probably benign	0.04

Predicted Primers

PCR Primer
(F):5'- TAGTAAGATTGACACTTTCCAGGAG -3'
(R):5'- AGACAGACCATTCTCTTCCATC -3'

Sequencing Primer
(F):5'- ACTTTCCAGGAGATAATATAGTAGGG -3'
(R):5'- TCTTCCATCAAGAGTCAGAGAGAAAC -3'

Posted On

2019-05-15