Incidental Mutation 'R0601:Myh15'
| ID |
55454 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Myh15
|
| Ensembl Gene |
ENSMUSG00000092009 |
| Gene Name |
myosin, heavy chain 15 |
| Synonyms |
EG667772 |
| MMRRC Submission |
038790-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.149)
|
| Stock # |
R0601 (G1)
|
| Quality Score |
220 |
|
Status
|
Validated
|
| Chromosome |
16 |
| Chromosomal Location |
48877849-49019467 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 48881944 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Aspartic acid to Valine
at position 62
(D62V)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000127539
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000168680]
|
| AlphaFold |
E9Q264 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000168680
AA Change: D62V
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000127539
Gene: ENSMUSG00000092009
AA Change: D62V
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Myosin_N
|
30 |
70 |
5.2e-12 |
PFAM |
|
MYSc
|
76 |
770 |
N/A |
SMART |
|
Pfam:Myosin_tail_1
|
836 |
1915 |
9.5e-118 |
PFAM |
|
| Meta Mutation Damage Score |
0.0745 |
| Coding Region Coverage |
- 1x: 99.4%
- 3x: 98.9%
- 10x: 97.6%
- 20x: 95.2%
|
| Validation Efficiency |
98% (119/122) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 119 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4930596D02Rik |
T |
G |
14: 35,532,146 (GRCm39) |
D143A |
probably damaging |
Het |
| Abca9 |
C |
T |
11: 110,007,884 (GRCm39) |
|
probably null |
Het |
| Abcc5 |
A |
G |
16: 20,223,309 (GRCm39) |
|
probably benign |
Het |
| Ablim3 |
T |
A |
18: 61,982,441 (GRCm39) |
D168V |
probably benign |
Het |
| Acsl3 |
C |
T |
1: 78,673,896 (GRCm39) |
S352F |
probably damaging |
Het |
| Adgrl4 |
A |
T |
3: 151,204,066 (GRCm39) |
|
probably benign |
Het |
| Arhgap29 |
A |
G |
3: 121,784,759 (GRCm39) |
K229E |
probably damaging |
Het |
| Atad3a |
A |
T |
4: 155,831,864 (GRCm39) |
V470D |
probably damaging |
Het |
| Atp8b1 |
A |
G |
18: 64,704,724 (GRCm39) |
|
probably null |
Het |
| Bcl2 |
G |
A |
1: 106,640,292 (GRCm39) |
R107C |
probably damaging |
Het |
| Bpifa5 |
A |
G |
2: 154,006,175 (GRCm39) |
N121S |
possibly damaging |
Het |
| Bpifb4 |
G |
A |
2: 153,789,203 (GRCm39) |
|
probably benign |
Het |
| Bptf |
T |
A |
11: 106,952,518 (GRCm39) |
T2112S |
probably benign |
Het |
| Btnl4 |
T |
C |
17: 34,688,285 (GRCm39) |
K498E |
probably benign |
Het |
| Calhm2 |
A |
G |
19: 47,129,469 (GRCm39) |
|
probably null |
Het |
| Capn3 |
A |
T |
2: 120,333,077 (GRCm39) |
|
probably null |
Het |
| Caps2 |
T |
C |
10: 112,031,695 (GRCm39) |
F265L |
possibly damaging |
Het |
| Casp3 |
G |
T |
8: 47,089,262 (GRCm39) |
C170F |
probably benign |
Het |
| Ccdc39 |
T |
C |
3: 33,873,988 (GRCm39) |
R615G |
probably damaging |
Het |
| Cd177 |
A |
G |
7: 24,451,738 (GRCm39) |
I426T |
probably benign |
Het |
| Cfap53 |
G |
A |
18: 74,433,221 (GRCm39) |
R102H |
possibly damaging |
Het |
| Cfhr3 |
G |
A |
1: 139,521,623 (GRCm39) |
|
noncoding transcript |
Het |
| Col7a1 |
T |
C |
9: 108,809,652 (GRCm39) |
|
probably benign |
Het |
| Cplx3 |
T |
C |
9: 57,513,357 (GRCm39) |
E24G |
possibly damaging |
Het |
| Dhx30 |
A |
G |
9: 109,915,782 (GRCm39) |
|
probably null |
Het |
| Dnah8 |
T |
A |
17: 30,927,332 (GRCm39) |
N1329K |
probably benign |
Het |
| Dnajc11 |
C |
G |
4: 152,054,393 (GRCm39) |
R200G |
probably damaging |
Het |
| Dok3 |
A |
T |
13: 55,672,076 (GRCm39) |
F201I |
probably benign |
Het |
| Dpf2 |
A |
T |
19: 5,952,240 (GRCm39) |
H303Q |
probably damaging |
Het |
| Dtnb |
A |
G |
12: 3,785,039 (GRCm39) |
|
probably benign |
Het |
| Dync2i1 |
T |
C |
12: 116,219,555 (GRCm39) |
D129G |
possibly damaging |
Het |
| Elk3 |
T |
C |
10: 93,101,343 (GRCm39) |
E136G |
probably damaging |
Het |
| Ephb1 |
T |
C |
9: 102,072,329 (GRCm39) |
D150G |
probably damaging |
Het |
| Erbb3 |
A |
G |
10: 128,412,881 (GRCm39) |
S570P |
probably benign |
Het |
| F2 |
A |
T |
2: 91,463,656 (GRCm39) |
|
probably null |
Het |
| Fanca |
A |
T |
8: 124,035,252 (GRCm39) |
M231K |
probably damaging |
Het |
| Fbxo34 |
T |
C |
14: 47,767,714 (GRCm39) |
V358A |
probably benign |
Het |
| Foxp1 |
C |
T |
6: 98,907,083 (GRCm39) |
E666K |
probably damaging |
Het |
| Fto |
A |
G |
8: 92,128,430 (GRCm39) |
|
probably null |
Het |
| Gbp2 |
C |
T |
3: 142,336,519 (GRCm39) |
R290C |
possibly damaging |
Het |
| Gm57859 |
T |
A |
11: 113,578,712 (GRCm39) |
S36T |
probably benign |
Het |
| Grik2 |
T |
G |
10: 49,298,693 (GRCm39) |
S343R |
probably damaging |
Het |
| Heatr5b |
A |
T |
17: 79,075,974 (GRCm39) |
M1448K |
probably benign |
Het |
| Hmgn3 |
A |
T |
9: 83,028,482 (GRCm39) |
|
probably null |
Het |
| Htt |
T |
C |
5: 35,003,347 (GRCm39) |
V1274A |
probably benign |
Het |
| Kcnh8 |
A |
G |
17: 53,201,033 (GRCm39) |
D489G |
probably damaging |
Het |
| Kcnip3 |
A |
T |
2: 127,300,317 (GRCm39) |
|
probably benign |
Het |
| Kdm5a |
A |
G |
6: 120,379,632 (GRCm39) |
T647A |
possibly damaging |
Het |
| Krt72 |
T |
C |
15: 101,694,491 (GRCm39) |
R135G |
probably damaging |
Het |
| Larp7 |
T |
A |
3: 127,337,858 (GRCm39) |
K400N |
probably damaging |
Het |
| Lifr |
T |
C |
15: 7,198,753 (GRCm39) |
|
probably null |
Het |
| Lima1 |
G |
A |
15: 99,678,353 (GRCm39) |
P696L |
probably damaging |
Het |
| Lrrc8e |
T |
G |
8: 4,285,239 (GRCm39) |
|
probably null |
Het |
| Map1a |
A |
G |
2: 121,129,083 (GRCm39) |
R116G |
probably damaging |
Het |
| Map3k13 |
A |
G |
16: 21,723,999 (GRCm39) |
E327G |
possibly damaging |
Het |
| Med13 |
A |
G |
11: 86,236,788 (GRCm39) |
V123A |
possibly damaging |
Het |
| Megf8 |
A |
C |
7: 25,027,965 (GRCm39) |
H205P |
probably benign |
Het |
| Met |
G |
A |
6: 17,555,631 (GRCm39) |
|
probably null |
Het |
| Mfsd14b |
A |
C |
13: 65,234,964 (GRCm39) |
V71G |
possibly damaging |
Het |
| Mpl |
T |
A |
4: 118,300,733 (GRCm39) |
T599S |
probably benign |
Het |
| Myo5a |
A |
G |
9: 75,081,297 (GRCm39) |
T961A |
probably benign |
Het |
| Myrfl |
A |
G |
10: 116,612,665 (GRCm39) |
Y895H |
probably damaging |
Het |
| Nap1l1 |
T |
C |
10: 111,326,224 (GRCm39) |
|
probably benign |
Het |
| Ncapd3 |
T |
A |
9: 26,952,803 (GRCm39) |
Y111N |
probably benign |
Het |
| Nlrc3 |
A |
G |
16: 3,766,113 (GRCm39) |
|
probably benign |
Het |
| Nsun2 |
G |
T |
13: 69,781,361 (GRCm39) |
V657L |
probably benign |
Het |
| Or10g1b |
C |
A |
14: 52,627,283 (GRCm39) |
G316* |
probably null |
Het |
| Or4a74 |
T |
A |
2: 89,439,564 (GRCm39) |
N294I |
probably benign |
Het |
| Or4b13 |
T |
C |
2: 90,083,278 (GRCm39) |
D18G |
probably benign |
Het |
| Or52d1 |
A |
T |
7: 103,756,349 (GRCm39) |
I288F |
possibly damaging |
Het |
| Or52e19 |
T |
C |
7: 102,959,371 (GRCm39) |
S148P |
probably damaging |
Het |
| Or5k3 |
G |
A |
16: 58,970,117 (GRCm39) |
M301I |
probably benign |
Het |
| Or5m13b |
A |
T |
2: 85,753,722 (GRCm39) |
I37F |
probably benign |
Het |
| Or6c68 |
T |
A |
10: 129,157,885 (GRCm39) |
M131K |
possibly damaging |
Het |
| Osbpl3 |
A |
T |
6: 50,276,383 (GRCm39) |
V795D |
probably benign |
Het |
| Osbpl5 |
T |
C |
7: 143,263,286 (GRCm39) |
D155G |
probably damaging |
Het |
| Parm1 |
G |
A |
5: 91,742,123 (GRCm39) |
V164I |
probably benign |
Het |
| Pgd |
A |
T |
4: 149,241,267 (GRCm39) |
|
probably benign |
Het |
| Pkp1 |
G |
A |
1: 135,805,920 (GRCm39) |
R593W |
probably damaging |
Het |
| Polr2l |
A |
T |
7: 141,053,255 (GRCm39) |
V53E |
probably damaging |
Het |
| Ppp4c |
G |
T |
7: 126,386,460 (GRCm39) |
T29K |
probably benign |
Het |
| Ppp4r4 |
T |
A |
12: 103,566,779 (GRCm39) |
|
probably benign |
Het |
| Ptprd |
A |
G |
4: 76,018,711 (GRCm39) |
S688P |
probably benign |
Het |
| Rab3b |
A |
T |
4: 108,747,586 (GRCm39) |
I28F |
probably damaging |
Het |
| Rnase4 |
T |
C |
14: 51,342,552 (GRCm39) |
L92P |
probably benign |
Het |
| Rnpc3 |
T |
C |
3: 113,413,755 (GRCm39) |
E229G |
probably benign |
Het |
| Rtraf |
A |
T |
14: 19,866,274 (GRCm39) |
D147E |
possibly damaging |
Het |
| Rttn |
G |
A |
18: 89,061,090 (GRCm39) |
G1086D |
probably benign |
Het |
| Ryr2 |
A |
G |
13: 11,720,519 (GRCm39) |
|
probably null |
Het |
| Sft2d2 |
T |
C |
1: 165,011,430 (GRCm39) |
I126V |
probably benign |
Het |
| Skap1 |
G |
T |
11: 96,614,236 (GRCm39) |
|
probably benign |
Het |
| Slc14a2 |
A |
T |
18: 78,200,394 (GRCm39) |
L753* |
probably null |
Het |
| Slc25a5 |
G |
A |
X: 36,059,408 (GRCm39) |
A9T |
probably benign |
Het |
| Slc30a5 |
T |
C |
13: 100,951,278 (GRCm39) |
|
probably benign |
Het |
| Slc5a4b |
A |
C |
10: 75,899,870 (GRCm39) |
I456S |
possibly damaging |
Het |
| Slc9a4 |
A |
T |
1: 40,642,230 (GRCm39) |
S400C |
probably damaging |
Het |
| Slx1b |
T |
A |
7: 126,291,812 (GRCm39) |
H84L |
probably damaging |
Het |
| Sptbn1 |
T |
C |
11: 30,100,008 (GRCm39) |
Y190C |
probably damaging |
Het |
| Stk32b |
T |
C |
5: 37,688,910 (GRCm39) |
Q138R |
probably damaging |
Het |
| Syt6 |
C |
A |
3: 103,528,206 (GRCm39) |
D308E |
probably damaging |
Het |
| Sytl2 |
G |
A |
7: 90,044,374 (GRCm39) |
D572N |
probably damaging |
Het |
| Taok2 |
A |
T |
7: 126,478,605 (GRCm39) |
L109Q |
probably damaging |
Het |
| Tbl1xr1 |
T |
C |
3: 22,233,483 (GRCm39) |
|
probably benign |
Het |
| Tlk1 |
A |
G |
2: 70,544,502 (GRCm39) |
I711T |
probably benign |
Het |
| Trf |
A |
G |
9: 103,100,132 (GRCm39) |
|
probably null |
Het |
| Trpc2 |
A |
G |
7: 101,733,572 (GRCm39) |
T548A |
possibly damaging |
Het |
| Ttbk2 |
A |
T |
2: 120,655,777 (GRCm39) |
I29N |
possibly damaging |
Het |
| Tti1 |
A |
T |
2: 157,835,292 (GRCm39) |
C989S |
probably damaging |
Het |
| Txndc8 |
A |
G |
4: 58,000,256 (GRCm39) |
Y108H |
probably benign |
Het |
| Ugt2b1 |
A |
T |
5: 87,065,539 (GRCm39) |
V500D |
possibly damaging |
Het |
| Vmn1r34 |
A |
G |
6: 66,614,648 (GRCm39) |
I30T |
possibly damaging |
Het |
| Vmn2r115 |
A |
G |
17: 23,579,074 (GRCm39) |
K849R |
probably null |
Het |
| Vmn2r76 |
T |
A |
7: 85,875,323 (GRCm39) |
|
probably null |
Het |
| Vps13c |
T |
A |
9: 67,834,754 (GRCm39) |
S1694R |
probably benign |
Het |
| Wdfy3 |
G |
T |
5: 101,984,038 (GRCm39) |
P3509T |
probably benign |
Het |
| Wdr59 |
GGGTGGTG |
GGGTG |
8: 112,207,172 (GRCm39) |
|
probably benign |
Het |
| Wnt8b |
T |
A |
19: 44,482,106 (GRCm39) |
W40R |
probably benign |
Het |
| Xrra1 |
A |
G |
7: 99,560,175 (GRCm39) |
I384V |
possibly damaging |
Het |
| Zfp11 |
A |
T |
5: 129,734,971 (GRCm39) |
H163Q |
probably damaging |
Het |
|
| Other mutations in Myh15 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00943:Myh15
|
APN |
16 |
48,986,176 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL01095:Myh15
|
APN |
16 |
48,952,378 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01343:Myh15
|
APN |
16 |
48,976,040 (GRCm39) |
missense |
probably benign |
0.09 |
|
IGL01474:Myh15
|
APN |
16 |
48,952,461 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01572:Myh15
|
APN |
16 |
48,920,585 (GRCm39) |
missense |
possibly damaging |
0.55 |
|
IGL01595:Myh15
|
APN |
16 |
48,993,312 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01632:Myh15
|
APN |
16 |
48,881,874 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01638:Myh15
|
APN |
16 |
48,889,843 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01667:Myh15
|
APN |
16 |
49,015,942 (GRCm39) |
missense |
probably benign |
0.20 |
|
IGL01715:Myh15
|
APN |
16 |
48,877,847 (GRCm39) |
unclassified |
probably benign |
|
|
IGL01833:Myh15
|
APN |
16 |
48,934,421 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02004:Myh15
|
APN |
16 |
48,930,892 (GRCm39) |
splice site |
probably benign |
|
|
IGL02033:Myh15
|
APN |
16 |
48,965,707 (GRCm39) |
missense |
probably benign |
0.05 |
|
IGL02148:Myh15
|
APN |
16 |
48,936,678 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02225:Myh15
|
APN |
16 |
48,911,526 (GRCm39) |
missense |
probably benign |
0.14 |
|
IGL02249:Myh15
|
APN |
16 |
48,930,847 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02505:Myh15
|
APN |
16 |
48,937,626 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
IGL02622:Myh15
|
APN |
16 |
48,997,317 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL02814:Myh15
|
APN |
16 |
48,965,801 (GRCm39) |
splice site |
probably benign |
|
|
IGL02869:Myh15
|
APN |
16 |
48,965,767 (GRCm39) |
missense |
probably benign |
|
|
IGL02879:Myh15
|
APN |
16 |
48,993,422 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
IGL02881:Myh15
|
APN |
16 |
48,937,628 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
IGL03077:Myh15
|
APN |
16 |
48,916,901 (GRCm39) |
missense |
probably benign |
0.10 |
|
IGL03354:Myh15
|
APN |
16 |
48,992,373 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL03411:Myh15
|
APN |
16 |
48,980,330 (GRCm39) |
missense |
possibly damaging |
0.58 |
|
ANU74:Myh15
|
UTSW |
16 |
48,993,295 (GRCm39) |
missense |
possibly damaging |
0.58 |
|
P0027:Myh15
|
UTSW |
16 |
48,901,571 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
PIT1430001:Myh15
|
UTSW |
16 |
49,017,254 (GRCm39) |
critical splice donor site |
probably null |
|
|
R0017:Myh15
|
UTSW |
16 |
48,983,423 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R0038:Myh15
|
UTSW |
16 |
48,891,504 (GRCm39) |
splice site |
probably benign |
|
|
R0149:Myh15
|
UTSW |
16 |
48,934,368 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0361:Myh15
|
UTSW |
16 |
48,934,368 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0373:Myh15
|
UTSW |
16 |
49,003,322 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R0433:Myh15
|
UTSW |
16 |
48,965,599 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0525:Myh15
|
UTSW |
16 |
48,952,414 (GRCm39) |
missense |
probably benign |
0.03 |
|
R0586:Myh15
|
UTSW |
16 |
48,992,250 (GRCm39) |
splice site |
probably benign |
|
|
R0717:Myh15
|
UTSW |
16 |
48,963,356 (GRCm39) |
missense |
probably benign |
0.03 |
|
R0963:Myh15
|
UTSW |
16 |
48,952,512 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R1075:Myh15
|
UTSW |
16 |
48,940,417 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R1143:Myh15
|
UTSW |
16 |
48,885,449 (GRCm39) |
missense |
probably benign |
0.02 |
|
R1200:Myh15
|
UTSW |
16 |
48,916,882 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1644:Myh15
|
UTSW |
16 |
48,952,566 (GRCm39) |
missense |
probably benign |
0.12 |
|
R1646:Myh15
|
UTSW |
16 |
49,015,931 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1720:Myh15
|
UTSW |
16 |
48,913,145 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1768:Myh15
|
UTSW |
16 |
48,983,498 (GRCm39) |
missense |
probably benign |
0.27 |
|
R1881:Myh15
|
UTSW |
16 |
48,891,446 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R2048:Myh15
|
UTSW |
16 |
48,975,928 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2064:Myh15
|
UTSW |
16 |
48,975,984 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R2184:Myh15
|
UTSW |
16 |
48,957,874 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2212:Myh15
|
UTSW |
16 |
48,959,095 (GRCm39) |
missense |
probably benign |
0.02 |
|
R2216:Myh15
|
UTSW |
16 |
48,986,201 (GRCm39) |
nonsense |
probably null |
|
|
R2321:Myh15
|
UTSW |
16 |
48,933,436 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R2327:Myh15
|
UTSW |
16 |
48,963,313 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2395:Myh15
|
UTSW |
16 |
48,889,877 (GRCm39) |
missense |
probably benign |
0.04 |
|
R2399:Myh15
|
UTSW |
16 |
48,957,952 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R3413:Myh15
|
UTSW |
16 |
48,959,095 (GRCm39) |
missense |
probably benign |
0.02 |
|
R4234:Myh15
|
UTSW |
16 |
48,983,405 (GRCm39) |
missense |
probably benign |
0.04 |
|
R4382:Myh15
|
UTSW |
16 |
48,963,306 (GRCm39) |
missense |
probably benign |
0.03 |
|
R4421:Myh15
|
UTSW |
16 |
48,929,707 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4580:Myh15
|
UTSW |
16 |
48,885,388 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R4657:Myh15
|
UTSW |
16 |
48,992,421 (GRCm39) |
nonsense |
probably null |
|
|
R4780:Myh15
|
UTSW |
16 |
48,940,420 (GRCm39) |
missense |
probably benign |
0.13 |
|
R5004:Myh15
|
UTSW |
16 |
48,952,411 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5175:Myh15
|
UTSW |
16 |
48,889,789 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R5189:Myh15
|
UTSW |
16 |
48,921,870 (GRCm39) |
missense |
probably benign |
0.20 |
|
R5311:Myh15
|
UTSW |
16 |
48,986,204 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R5318:Myh15
|
UTSW |
16 |
48,930,834 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5404:Myh15
|
UTSW |
16 |
48,980,341 (GRCm39) |
missense |
probably benign |
0.15 |
|
R5415:Myh15
|
UTSW |
16 |
48,937,658 (GRCm39) |
missense |
probably null |
1.00 |
|
R5558:Myh15
|
UTSW |
16 |
48,889,900 (GRCm39) |
missense |
probably benign |
0.32 |
|
R5977:Myh15
|
UTSW |
16 |
48,973,866 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6004:Myh15
|
UTSW |
16 |
48,980,062 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6275:Myh15
|
UTSW |
16 |
48,965,610 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6381:Myh15
|
UTSW |
16 |
48,921,844 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6448:Myh15
|
UTSW |
16 |
48,992,295 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6516:Myh15
|
UTSW |
16 |
48,957,996 (GRCm39) |
missense |
probably benign |
0.19 |
|
R6752:Myh15
|
UTSW |
16 |
49,003,290 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6847:Myh15
|
UTSW |
16 |
48,965,451 (GRCm39) |
missense |
possibly damaging |
0.70 |
|
R6868:Myh15
|
UTSW |
16 |
48,889,766 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6889:Myh15
|
UTSW |
16 |
48,973,474 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R6896:Myh15
|
UTSW |
16 |
48,933,434 (GRCm39) |
missense |
probably benign |
0.44 |
|
R6955:Myh15
|
UTSW |
16 |
48,901,598 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6984:Myh15
|
UTSW |
16 |
48,930,775 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7046:Myh15
|
UTSW |
16 |
48,929,662 (GRCm39) |
nonsense |
probably null |
|
|
R7095:Myh15
|
UTSW |
16 |
48,992,272 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R7098:Myh15
|
UTSW |
16 |
48,997,420 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R7134:Myh15
|
UTSW |
16 |
48,901,705 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R7159:Myh15
|
UTSW |
16 |
48,881,937 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R7244:Myh15
|
UTSW |
16 |
49,017,149 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7278:Myh15
|
UTSW |
16 |
48,911,468 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7309:Myh15
|
UTSW |
16 |
48,916,828 (GRCm39) |
missense |
probably benign |
0.34 |
|
R7327:Myh15
|
UTSW |
16 |
48,993,369 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R7418:Myh15
|
UTSW |
16 |
48,975,900 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R7937:Myh15
|
UTSW |
16 |
48,976,009 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8053:Myh15
|
UTSW |
16 |
48,963,302 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R8313:Myh15
|
UTSW |
16 |
48,940,381 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8315:Myh15
|
UTSW |
16 |
48,940,381 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8316:Myh15
|
UTSW |
16 |
48,940,381 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8317:Myh15
|
UTSW |
16 |
48,940,381 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8342:Myh15
|
UTSW |
16 |
48,913,120 (GRCm39) |
missense |
probably benign |
|
|
R8379:Myh15
|
UTSW |
16 |
48,901,551 (GRCm39) |
missense |
probably benign |
|
|
R8445:Myh15
|
UTSW |
16 |
48,940,381 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8707:Myh15
|
UTSW |
16 |
48,973,450 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8729:Myh15
|
UTSW |
16 |
48,881,851 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R8773:Myh15
|
UTSW |
16 |
49,015,900 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R8869:Myh15
|
UTSW |
16 |
48,997,366 (GRCm39) |
missense |
probably benign |
|
|
R8890:Myh15
|
UTSW |
16 |
48,959,130 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9026:Myh15
|
UTSW |
16 |
49,007,433 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9063:Myh15
|
UTSW |
16 |
48,913,118 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9290:Myh15
|
UTSW |
16 |
48,997,375 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9630:Myh15
|
UTSW |
16 |
48,980,341 (GRCm39) |
missense |
probably benign |
0.15 |
|
R9710:Myh15
|
UTSW |
16 |
48,959,044 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0012:Myh15
|
UTSW |
16 |
48,963,341 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0020:Myh15
|
UTSW |
16 |
48,986,237 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1176:Myh15
|
UTSW |
16 |
48,916,894 (GRCm39) |
missense |
probably damaging |
0.98 |
|
Z1177:Myh15
|
UTSW |
16 |
48,980,189 (GRCm39) |
missense |
probably benign |
0.09 |
|
Z1177:Myh15
|
UTSW |
16 |
48,975,981 (GRCm39) |
missense |
probably damaging |
0.97 |
|
Z1177:Myh15
|
UTSW |
16 |
48,901,591 (GRCm39) |
missense |
probably benign |
0.02 |
|
| Predicted Primers |
PCR Primer
(F):5'- GCCCATGAGGCTGGCAGAAA -3'
(R):5'- GCAGAAGTTACTAgaagggaggaaggga -3'
Sequencing Primer
(F):5'- TGATAGCTCCAAGACTTGGTAG -3'
(R):5'- gaagggaggaagggaagaag -3'
|
| Posted On |
2013-07-11 |
Incidental Mutation