Incidental Mutation 'PIT4362001:Zfp407'
| ID |
554659 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Zfp407
|
| Ensembl Gene |
ENSMUSG00000048410 |
| Gene Name |
zinc finger protein 407 |
| Synonyms |
LOC381139, 6430585N13Rik, LOC240469 |
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
PIT4362001 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
18 |
| Chromosomal Location |
84225826-84612815 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 84579393 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Asparagine to Lysine
at position 573
(N573K)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000118361
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000125763]
|
| AlphaFold |
G3UVV3 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000125450
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000125763
AA Change: N573K
PolyPhen 2
Score 0.873 (Sensitivity: 0.83; Specificity: 0.93)
|
| SMART Domains |
Protein: ENSMUSP00000118361
Gene: ENSMUSG00000048410
AA Change: N573K
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
20 |
37 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
178 |
200 |
8.67e-1 |
SMART |
|
ZnF_U1
|
233 |
267 |
6.79e-1 |
SMART |
|
ZnF_C2H2
|
236 |
260 |
4.65e-1 |
SMART |
|
ZnF_C2H2
|
522 |
545 |
7.05e-1 |
SMART |
|
ZnF_U1
|
548 |
582 |
1.54e1 |
SMART |
|
ZnF_C2H2
|
551 |
575 |
1.01e-1 |
SMART |
|
ZnF_C2H2
|
582 |
605 |
1.41e0 |
SMART |
|
ZnF_U1
|
606 |
639 |
2.22e0 |
SMART |
|
ZnF_C2H2
|
609 |
632 |
1.01e2 |
SMART |
|
ZnF_C2H2
|
695 |
718 |
6.23e-2 |
SMART |
|
ZnF_U1
|
721 |
755 |
2.96e0 |
SMART |
|
ZnF_C2H2
|
724 |
748 |
7.11e0 |
SMART |
|
ZnF_C2H2
|
840 |
863 |
7.55e-1 |
SMART |
|
ZnF_U1
|
866 |
900 |
3.81e-1 |
SMART |
|
ZnF_C2H2
|
869 |
893 |
1.07e0 |
SMART |
|
ZnF_C2H2
|
1009 |
1032 |
6.13e-1 |
SMART |
|
ZnF_U1
|
1035 |
1069 |
2.22e0 |
SMART |
|
ZnF_C2H2
|
1038 |
1062 |
5.62e0 |
SMART |
|
low complexity region
|
1223 |
1234 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
1405 |
1428 |
5.92e0 |
SMART |
|
ZnF_U1
|
1432 |
1466 |
2.35e0 |
SMART |
|
ZnF_C2H2
|
1435 |
1459 |
1.76e-1 |
SMART |
|
ZnF_C2H2
|
1477 |
1500 |
5.42e-2 |
SMART |
|
ZnF_C2H2
|
1528 |
1552 |
1.68e1 |
SMART |
|
ZnF_C2H2
|
1558 |
1580 |
1.43e-1 |
SMART |
|
ZnF_C2H2
|
1586 |
1609 |
9.58e-3 |
SMART |
|
ZnF_C2H2
|
1619 |
1641 |
2.61e-4 |
SMART |
|
ZnF_C2H2
|
1647 |
1671 |
1.04e-3 |
SMART |
|
ZnF_C2H2
|
1677 |
1699 |
9.44e-2 |
SMART |
|
ZnF_C2H2
|
1705 |
1727 |
1.82e-3 |
SMART |
|
ZnF_C2H2
|
1733 |
1758 |
4.65e-1 |
SMART |
|
ZnF_C2H2
|
1764 |
1787 |
1.26e-2 |
SMART |
|
low complexity region
|
1876 |
1887 |
N/A |
INTRINSIC |
|
low complexity region
|
2017 |
2032 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 93.4%
- 3x: 91.2%
- 10x: 87.0%
- 20x: 78.3%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a zinc finger protein whose exact function is not known. It may be involved in transcriptional regulation. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 71 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abcg1 |
T |
C |
17: 31,283,398 (GRCm39) |
S28P |
possibly damaging |
Het |
| Akr1c14 |
T |
C |
13: 4,129,100 (GRCm39) |
V165A |
probably damaging |
Het |
| Aox1 |
A |
T |
1: 58,321,839 (GRCm39) |
T44S |
probably damaging |
Het |
| Arhgap29 |
T |
A |
3: 121,796,861 (GRCm39) |
N482K |
probably benign |
Het |
| Arhgef38 |
T |
A |
3: 132,866,591 (GRCm39) |
D182V |
|
Het |
| Atad5 |
C |
T |
11: 80,002,393 (GRCm39) |
H1062Y |
probably benign |
Het |
| Atp6v0b |
A |
G |
4: 117,742,453 (GRCm39) |
S147P |
possibly damaging |
Het |
| Cblb |
T |
A |
16: 51,959,905 (GRCm39) |
Y299* |
probably null |
Het |
| Ccdc28b |
T |
C |
4: 129,514,818 (GRCm39) |
N97S |
probably benign |
Het |
| Cdh23 |
A |
G |
10: 60,301,237 (GRCm39) |
V479A |
probably benign |
Het |
| Chuk |
A |
G |
19: 44,087,022 (GRCm39) |
|
probably null |
Het |
| Cmtr2 |
G |
A |
8: 110,948,968 (GRCm39) |
G426D |
probably damaging |
Het |
| Cog4 |
G |
A |
8: 111,593,304 (GRCm39) |
D472N |
probably damaging |
Het |
| Creb3 |
T |
A |
4: 43,565,472 (GRCm39) |
L193* |
probably null |
Het |
| Cxcr6 |
A |
T |
9: 123,639,526 (GRCm39) |
I183F |
probably benign |
Het |
| Dbf4 |
A |
G |
5: 8,453,664 (GRCm39) |
F253L |
probably benign |
Het |
| Dcaf8 |
T |
C |
1: 172,000,364 (GRCm39) |
V174A |
probably damaging |
Het |
| Ddhd2 |
T |
C |
8: 26,225,779 (GRCm39) |
Y526C |
probably damaging |
Het |
| Dnal4 |
A |
G |
15: 79,647,766 (GRCm39) |
V33A |
probably benign |
Het |
| Egfl7 |
C |
T |
2: 26,481,052 (GRCm39) |
P188L |
probably benign |
Het |
| Ephb3 |
A |
G |
16: 21,039,607 (GRCm39) |
E707G |
probably damaging |
Het |
| Epn3 |
C |
T |
11: 94,387,349 (GRCm39) |
R7H |
probably damaging |
Het |
| Fbp1 |
T |
A |
13: 63,015,194 (GRCm39) |
I262F |
probably damaging |
Het |
| Fgfbp3 |
G |
A |
19: 36,896,088 (GRCm39) |
R177* |
probably null |
Het |
| Gask1b |
C |
A |
3: 79,794,246 (GRCm39) |
S238Y |
possibly damaging |
Het |
| Gbp5 |
T |
C |
3: 142,206,471 (GRCm39) |
S52P |
probably damaging |
Het |
| Glb1l2 |
A |
T |
9: 26,685,277 (GRCm39) |
S282T |
probably benign |
Het |
| Glg1 |
A |
T |
8: 111,985,431 (GRCm39) |
V133E |
possibly damaging |
Het |
| Gm4787 |
T |
G |
12: 81,423,949 (GRCm39) |
L736F |
probably benign |
Het |
| Gm5565 |
A |
T |
5: 146,095,109 (GRCm39) |
S212R |
probably benign |
Het |
| Grin2c |
T |
C |
11: 115,140,459 (GRCm39) |
T1220A |
probably benign |
Het |
| Grp |
T |
G |
18: 66,019,297 (GRCm39) |
S133A |
probably benign |
Het |
| Gstp2 |
C |
A |
19: 4,090,713 (GRCm39) |
D147Y |
possibly damaging |
Het |
| Igkv14-130 |
T |
C |
6: 67,768,392 (GRCm39) |
F84L |
probably damaging |
Het |
| Inppl1 |
T |
C |
7: 101,475,220 (GRCm39) |
R944G |
probably benign |
Het |
| Lama2 |
A |
T |
10: 27,245,132 (GRCm39) |
N216K |
probably damaging |
Het |
| Lrp2 |
T |
A |
2: 69,367,882 (GRCm39) |
D210V |
probably damaging |
Het |
| Lrrc2 |
A |
T |
9: 110,791,608 (GRCm39) |
Q120L |
possibly damaging |
Het |
| Lrriq1 |
A |
G |
10: 102,907,055 (GRCm39) |
I1555T |
probably benign |
Het |
| Map2 |
G |
A |
1: 66,451,677 (GRCm39) |
G189D |
probably benign |
Het |
| Mdc1 |
A |
G |
17: 36,155,361 (GRCm39) |
E12G |
possibly damaging |
Het |
| Mdga2 |
T |
C |
12: 66,844,542 (GRCm39) |
D152G |
possibly damaging |
Het |
| Med23 |
A |
G |
10: 24,750,469 (GRCm39) |
M99V |
probably benign |
Het |
| Mutyh |
G |
A |
4: 116,674,267 (GRCm39) |
V273M |
probably damaging |
Het |
| Neurod2 |
T |
A |
11: 98,218,708 (GRCm39) |
Y152F |
probably damaging |
Het |
| Or5d3 |
C |
T |
2: 88,174,357 (GRCm39) |
A247T |
probably benign |
Het |
| Or5g25 |
A |
C |
2: 85,478,068 (GRCm39) |
L199R |
probably damaging |
Het |
| Or8c20 |
G |
T |
9: 38,260,494 (GRCm39) |
L32F |
probably benign |
Het |
| Pcdh20 |
G |
C |
14: 88,704,462 (GRCm39) |
P946R |
probably damaging |
Het |
| Pde6b |
T |
C |
5: 108,571,451 (GRCm39) |
|
probably null |
Het |
| Pdzrn4 |
A |
T |
15: 92,667,762 (GRCm39) |
D638V |
possibly damaging |
Het |
| Polr1b |
A |
G |
2: 128,951,212 (GRCm39) |
D275G |
possibly damaging |
Het |
| Rnf157 |
T |
A |
11: 116,251,143 (GRCm39) |
D127V |
probably damaging |
Het |
| Rspo4 |
T |
A |
2: 151,709,803 (GRCm39) |
C69* |
probably null |
Het |
| Scara3 |
T |
C |
14: 66,173,851 (GRCm39) |
T63A |
probably benign |
Het |
| Scn2a |
G |
A |
2: 65,514,182 (GRCm39) |
E289K |
probably benign |
Het |
| Sh3gl2 |
A |
G |
4: 85,295,786 (GRCm39) |
T163A |
probably benign |
Het |
| Slc2a10 |
T |
A |
2: 165,358,213 (GRCm39) |
F446Y |
probably damaging |
Het |
| Snapc1 |
C |
T |
12: 74,029,269 (GRCm39) |
R351C |
probably damaging |
Het |
| Snx6 |
A |
G |
12: 54,814,815 (GRCm39) |
Y169H |
possibly damaging |
Het |
| Stab2 |
A |
T |
10: 86,697,299 (GRCm39) |
C1996* |
probably null |
Het |
| Steap4 |
A |
G |
5: 8,030,337 (GRCm39) |
T398A |
probably benign |
Het |
| Tep1 |
A |
T |
14: 51,103,510 (GRCm39) |
L260Q |
probably benign |
Het |
| Tspan12 |
A |
T |
6: 21,835,463 (GRCm39) |
V70D |
possibly damaging |
Het |
| Ttn |
G |
A |
2: 76,569,362 (GRCm39) |
A27177V |
probably damaging |
Het |
| Ube3a |
T |
C |
7: 58,925,870 (GRCm39) |
V237A |
possibly damaging |
Het |
| Vil1 |
G |
A |
1: 74,460,542 (GRCm39) |
R233H |
probably damaging |
Het |
| Xrcc5 |
A |
G |
1: 72,433,088 (GRCm39) |
T716A |
probably benign |
Het |
| Zbp1 |
A |
G |
2: 173,058,783 (GRCm39) |
I18T |
probably damaging |
Het |
| Zfp292 |
A |
G |
4: 34,807,524 (GRCm39) |
V1845A |
probably benign |
Het |
| Zfp64 |
T |
C |
2: 168,767,735 (GRCm39) |
T626A |
probably benign |
Het |
|
| Other mutations in Zfp407 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00499:Zfp407
|
APN |
18 |
84,579,877 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02105:Zfp407
|
APN |
18 |
84,580,845 (GRCm39) |
nonsense |
probably null |
|
|
IGL02110:Zfp407
|
APN |
18 |
84,577,165 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02343:Zfp407
|
APN |
18 |
84,227,849 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
IGL02456:Zfp407
|
APN |
18 |
84,576,766 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02705:Zfp407
|
APN |
18 |
84,577,156 (GRCm39) |
nonsense |
probably null |
|
|
IGL02946:Zfp407
|
APN |
18 |
84,578,834 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03069:Zfp407
|
APN |
18 |
84,369,100 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03145:Zfp407
|
APN |
18 |
84,227,846 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL03403:Zfp407
|
APN |
18 |
84,578,922 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03134:Zfp407
|
UTSW |
18 |
84,228,080 (GRCm39) |
missense |
probably damaging |
0.99 |
|
PIT4520001:Zfp407
|
UTSW |
18 |
84,450,545 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0087:Zfp407
|
UTSW |
18 |
84,578,536 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0243:Zfp407
|
UTSW |
18 |
84,576,836 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0594:Zfp407
|
UTSW |
18 |
84,580,692 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R0766:Zfp407
|
UTSW |
18 |
84,577,898 (GRCm39) |
missense |
probably benign |
0.14 |
|
R0787:Zfp407
|
UTSW |
18 |
84,227,471 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0787:Zfp407
|
UTSW |
18 |
84,227,147 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1065:Zfp407
|
UTSW |
18 |
84,577,898 (GRCm39) |
missense |
probably benign |
0.14 |
|
R1086:Zfp407
|
UTSW |
18 |
84,577,898 (GRCm39) |
missense |
probably benign |
0.14 |
|
R1165:Zfp407
|
UTSW |
18 |
84,577,898 (GRCm39) |
missense |
probably benign |
0.14 |
|
R1186:Zfp407
|
UTSW |
18 |
84,227,573 (GRCm39) |
missense |
probably benign |
0.39 |
|
R1203:Zfp407
|
UTSW |
18 |
84,577,898 (GRCm39) |
missense |
probably benign |
0.14 |
|
R1312:Zfp407
|
UTSW |
18 |
84,577,898 (GRCm39) |
missense |
probably benign |
0.14 |
|
R1345:Zfp407
|
UTSW |
18 |
84,577,898 (GRCm39) |
missense |
probably benign |
0.14 |
|
R1385:Zfp407
|
UTSW |
18 |
84,577,898 (GRCm39) |
missense |
probably benign |
0.14 |
|
R1421:Zfp407
|
UTSW |
18 |
84,577,898 (GRCm39) |
missense |
probably benign |
0.14 |
|
R1430:Zfp407
|
UTSW |
18 |
84,227,580 (GRCm39) |
missense |
probably benign |
0.18 |
|
R1436:Zfp407
|
UTSW |
18 |
84,361,196 (GRCm39) |
splice site |
probably benign |
|
|
R1498:Zfp407
|
UTSW |
18 |
84,577,898 (GRCm39) |
missense |
probably benign |
0.14 |
|
R1526:Zfp407
|
UTSW |
18 |
84,579,158 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
R1579:Zfp407
|
UTSW |
18 |
84,227,763 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1594:Zfp407
|
UTSW |
18 |
84,227,456 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1628:Zfp407
|
UTSW |
18 |
84,372,658 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1698:Zfp407
|
UTSW |
18 |
84,580,282 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1962:Zfp407
|
UTSW |
18 |
84,577,461 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1984:Zfp407
|
UTSW |
18 |
84,577,898 (GRCm39) |
missense |
probably benign |
0.14 |
|
R1985:Zfp407
|
UTSW |
18 |
84,577,898 (GRCm39) |
missense |
probably benign |
0.14 |
|
R1986:Zfp407
|
UTSW |
18 |
84,577,898 (GRCm39) |
missense |
probably benign |
0.14 |
|
R2151:Zfp407
|
UTSW |
18 |
84,227,774 (GRCm39) |
missense |
possibly damaging |
0.55 |
|
R2152:Zfp407
|
UTSW |
18 |
84,227,774 (GRCm39) |
missense |
possibly damaging |
0.55 |
|
R2154:Zfp407
|
UTSW |
18 |
84,227,774 (GRCm39) |
missense |
possibly damaging |
0.55 |
|
R2259:Zfp407
|
UTSW |
18 |
84,227,918 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2353:Zfp407
|
UTSW |
18 |
84,578,005 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2845:Zfp407
|
UTSW |
18 |
84,576,522 (GRCm39) |
nonsense |
probably null |
|
|
R3407:Zfp407
|
UTSW |
18 |
84,576,997 (GRCm39) |
missense |
probably benign |
0.08 |
|
R3432:Zfp407
|
UTSW |
18 |
84,226,871 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3892:Zfp407
|
UTSW |
18 |
84,578,477 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4026:Zfp407
|
UTSW |
18 |
84,577,721 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R4107:Zfp407
|
UTSW |
18 |
84,361,132 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R4398:Zfp407
|
UTSW |
18 |
84,580,856 (GRCm39) |
nonsense |
probably null |
|
|
R4447:Zfp407
|
UTSW |
18 |
84,580,819 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R4752:Zfp407
|
UTSW |
18 |
84,581,039 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4881:Zfp407
|
UTSW |
18 |
84,577,828 (GRCm39) |
missense |
probably benign |
0.27 |
|
R4936:Zfp407
|
UTSW |
18 |
84,577,589 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5194:Zfp407
|
UTSW |
18 |
84,579,434 (GRCm39) |
missense |
probably benign |
0.05 |
|
R5243:Zfp407
|
UTSW |
18 |
84,579,216 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5258:Zfp407
|
UTSW |
18 |
84,334,051 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5591:Zfp407
|
UTSW |
18 |
84,579,262 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5633:Zfp407
|
UTSW |
18 |
84,579,169 (GRCm39) |
missense |
probably benign |
0.35 |
|
R5739:Zfp407
|
UTSW |
18 |
84,226,867 (GRCm39) |
makesense |
probably null |
|
|
R5806:Zfp407
|
UTSW |
18 |
84,576,739 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5820:Zfp407
|
UTSW |
18 |
84,578,649 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6187:Zfp407
|
UTSW |
18 |
84,577,134 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R6512:Zfp407
|
UTSW |
18 |
84,578,474 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6521:Zfp407
|
UTSW |
18 |
84,450,536 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6748:Zfp407
|
UTSW |
18 |
84,226,955 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6882:Zfp407
|
UTSW |
18 |
84,361,194 (GRCm39) |
splice site |
probably null |
|
|
R6899:Zfp407
|
UTSW |
18 |
84,579,559 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R7038:Zfp407
|
UTSW |
18 |
84,579,982 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7076:Zfp407
|
UTSW |
18 |
84,576,601 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7326:Zfp407
|
UTSW |
18 |
84,577,167 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R7397:Zfp407
|
UTSW |
18 |
84,579,944 (GRCm39) |
missense |
possibly damaging |
0.59 |
|
R7402:Zfp407
|
UTSW |
18 |
84,579,661 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7783:Zfp407
|
UTSW |
18 |
84,228,047 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R7800:Zfp407
|
UTSW |
18 |
84,578,800 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7904:Zfp407
|
UTSW |
18 |
84,579,381 (GRCm39) |
missense |
not run |
|
|
R7942:Zfp407
|
UTSW |
18 |
84,577,754 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7955:Zfp407
|
UTSW |
18 |
84,577,416 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7988:Zfp407
|
UTSW |
18 |
84,577,525 (GRCm39) |
missense |
possibly damaging |
0.60 |
|
R8125:Zfp407
|
UTSW |
18 |
84,579,310 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8237:Zfp407
|
UTSW |
18 |
84,578,269 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R8364:Zfp407
|
UTSW |
18 |
84,570,993 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8443:Zfp407
|
UTSW |
18 |
84,227,987 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8487:Zfp407
|
UTSW |
18 |
84,580,895 (GRCm39) |
nonsense |
probably null |
|
|
R8497:Zfp407
|
UTSW |
18 |
84,578,021 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8808:Zfp407
|
UTSW |
18 |
84,361,185 (GRCm39) |
missense |
probably benign |
0.17 |
|
R8848:Zfp407
|
UTSW |
18 |
84,578,819 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8913:Zfp407
|
UTSW |
18 |
84,578,653 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8962:Zfp407
|
UTSW |
18 |
84,577,057 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9087:Zfp407
|
UTSW |
18 |
84,227,982 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R9452:Zfp407
|
UTSW |
18 |
84,580,579 (GRCm39) |
missense |
probably benign |
0.02 |
|
R9691:Zfp407
|
UTSW |
18 |
84,578,312 (GRCm39) |
missense |
probably benign |
0.03 |
|
R9766:Zfp407
|
UTSW |
18 |
84,577,574 (GRCm39) |
missense |
probably benign |
0.06 |
|
RF003:Zfp407
|
UTSW |
18 |
84,227,688 (GRCm39) |
missense |
probably benign |
0.17 |
|
Z1177:Zfp407
|
UTSW |
18 |
84,228,079 (GRCm39) |
missense |
probably damaging |
0.97 |
|
| Predicted Primers |
PCR Primer
(F):5'- AGCCGTCTTTGGTTGAACC -3'
(R):5'- TGCCAGTAAAGCCAGCTGAC -3'
Sequencing Primer
(F):5'- AACTATTATGTGACTCGGTTGCTC -3'
(R):5'- ACCACCAGCTCTCTGTGCAG -3'
|
| Posted On |
2019-06-07 |
Incidental Mutation