Mutagenetix > Incidental Mutation

Incidental Mutation 'PIT4618001:Vps13b'

555708

Institutional Source

Beutler Lab

Gene Symbol

Vps13b

Ensembl Gene

ENSMUSG00000037646

Gene Name

vacuolar protein sorting 13B

Synonyms

2310042E16Rik, 1810042B05Rik, Coh1, C330002D13Rik

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

PIT4618001 (G1)

Quality Score

225.009

Status

Not validated

Chromosome

Chromosomal Location

35371160-35931229 bp(+) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

C to T at 35709240 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Arginine to Cysteine at position 1778 (R1778C)

Ref Sequence

ENSEMBL: ENSMUSP00000045490 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000048646]

AlphaFold

no structure available at present

Predicted Effect

probably damaging
Transcript: ENSMUST00000048646
AA Change: R1778C

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)

SMART Domains

Protein: ENSMUSP00000045490
Gene: ENSMUSG00000037646
AA Change: R1778C

Domain	Start	End	E-Value	Type
Pfam:Chorein_N	2	120	1e-29	PFAM
low complexity region	128	137	N/A	INTRINSIC
low complexity region	143	160	N/A	INTRINSIC
low complexity region	975	984	N/A	INTRINSIC
low complexity region	1007	1018	N/A	INTRINSIC
low complexity region	1876	1883	N/A	INTRINSIC
low complexity region	2042	2054	N/A	INTRINSIC
low complexity region	2414	2423	N/A	INTRINSIC
Pfam:SHR-BD	2601	2700	8.4e-10	PFAM
low complexity region	2954	2964	N/A	INTRINSIC
Pfam:VPS13_C	3539	3706	2.6e-30	PFAM

Coding Region Coverage

1x: 93.4%
3x: 91.0%
10x: 85.9%
20x: 75.2%

Validation Efficiency

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a potential transmembrane protein that may function in vesicle-mediated transport and sorting of proteins within the cell. This protein may play a role in the development and the function of the eye, hematological system, and central nervous system. Mutations in this gene have been associated with Cohen syndrome. Multiple splice variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]

Allele List at MGI

Other mutations in this stock

Total: 37 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
1700028K03Rik	A	T	5: 107,545,709	D64V	probably damaging	Het
Ankdd1a	A	C	9: 65,507,650	I268S	possibly damaging	Het
Atad3a	C	T	4: 155,750,138	R402Q	probably benign	Het
C3ar1	A	G	6: 122,850,787	V157A	probably benign	Het
Cd55	C	T	1: 130,456,869	V206I	probably benign	Het
Cd8a	A	G	6: 71,373,677	D42G	possibly damaging	Het
Cemip	G	T	7: 83,943,939	F1185L	probably benign	Het
Cfap58	A	G	19: 47,975,514	D527G	probably damaging	Het
Cyp2a12	C	A	7: 27,034,773	S377Y	probably benign	Het
Dapk2	A	G	9: 66,268,686	D289G	probably benign	Het
Efcab6	G	A	15: 83,983,446	A277V	probably benign	Het
Ephx2	A	T	14: 66,102,222	F250L	probably damaging	Het
Flg2	A	T	3: 93,203,781	S1039C	unknown	Het
Gm609	A	G	16: 45,443,934	F87S	probably benign	Het
Gramd1a	A	G	7: 31,132,596	V674A	probably benign	Het
Gtf2a1	A	C	12: 91,567,769	V237G	probably benign	Het
I830077J02Rik	G	A	3: 105,926,570	T90M	probably damaging	Het
Jagn1	T	A	6: 113,447,437	L90H	probably damaging	Het
Mdn1	G	T	4: 32,746,527	A4158S	probably benign	Het
Myh11	G	A	16: 14,201,066	A1839V		Het
Olr1	G	A	6: 129,499,906	A132V	probably damaging	Het
Paqr3	A	T	5: 97,103,471	H131Q	possibly damaging	Het
Pde4b	A	T	4: 102,602,812	T397S	probably benign	Het
Pon1	A	G	6: 5,168,349	C353R	probably damaging	Het
Ppie	G	A	4: 123,138,868	T43I	probably null	Het
Prr5l	A	G	2: 101,758,530	F92L	probably damaging	Het
Rai14	T	C	15: 10,575,156	Y601C	probably damaging	Het
Rasal1	A	G	5: 120,670,376	D491G	probably damaging	Het
Rbm12b1	T	A	4: 12,145,441	V471E	probably damaging	Het
Rpusd2	T	C	2: 119,038,452	L452P	possibly damaging	Het
Scgb2b24	A	T	7: 33,738,611	C24S	probably damaging	Het
Slc17a5	C	T	9: 78,538,248	V468M	possibly damaging	Het
Tcp10c	A	G	17: 13,356,510	K117R	possibly damaging	Het
Ubash3b	A	G	9: 41,016,627	S584P	probably benign	Het
Ythdc2	A	G	18: 44,834,598	I220M	probably benign	Het
Zfp474	C	A	18: 52,638,404	T43K	probably damaging	Het
Zscan4-ps3	G	A	7: 11,613,334	M432I	probably benign	Het

Other mutations in Vps13b

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00402:Vps13b	APN	15	35,926,226 (GRCm38)	missense	possibly damaging	0.52
IGL00513:Vps13b	APN	15	35,793,884 (GRCm38)	missense	probably damaging	1.00
IGL00516:Vps13b	APN	15	35,640,557 (GRCm38)	missense	probably damaging	1.00
IGL00640:Vps13b	APN	15	35,417,577 (GRCm38)	missense	probably benign
IGL00753:Vps13b	APN	15	35,372,031 (GRCm38)	missense	probably damaging	0.99
IGL00784:Vps13b	APN	15	35,846,900 (GRCm38)	missense	probably damaging	1.00
IGL01138:Vps13b	APN	15	35,446,770 (GRCm38)	splice site	probably benign
IGL01349:Vps13b	APN	15	35,793,945 (GRCm38)	missense	probably benign	0.00
IGL01403:Vps13b	APN	15	35,709,479 (GRCm38)	missense	probably benign	0.00
IGL01535:Vps13b	APN	15	35,454,957 (GRCm38)	missense	possibly damaging	0.67
IGL01571:Vps13b	APN	15	35,877,489 (GRCm38)	splice site	probably benign
IGL01642:Vps13b	APN	15	35,792,072 (GRCm38)	missense	probably benign	0.43
IGL01658:Vps13b	APN	15	35,671,333 (GRCm38)	missense	probably damaging	0.99
IGL01759:Vps13b	APN	15	35,878,789 (GRCm38)	missense	probably damaging	1.00
IGL01763:Vps13b	APN	15	35,709,799 (GRCm38)	missense	possibly damaging	0.72
IGL01906:Vps13b	APN	15	35,639,847 (GRCm38)	splice site	probably benign
IGL01982:Vps13b	APN	15	35,438,904 (GRCm38)	nonsense	probably null
IGL01997:Vps13b	APN	15	35,709,224 (GRCm38)	missense	probably damaging	1.00
IGL02041:Vps13b	APN	15	35,423,245 (GRCm38)	missense	probably damaging	0.98
IGL02073:Vps13b	APN	15	35,875,586 (GRCm38)	missense	possibly damaging	0.52
IGL02077:Vps13b	APN	15	35,910,613 (GRCm38)	missense	possibly damaging	0.68
IGL02141:Vps13b	APN	15	35,572,081 (GRCm38)	missense	probably benign	0.09
IGL02146:Vps13b	APN	15	35,646,333 (GRCm38)	missense	probably benign	0.36
IGL02197:Vps13b	APN	15	35,930,056 (GRCm38)	missense	probably benign	0.02
IGL02311:Vps13b	APN	15	35,709,514 (GRCm38)	missense	probably benign	0.08
IGL02466:Vps13b	APN	15	35,770,741 (GRCm38)	missense	possibly damaging	0.86
IGL02506:Vps13b	APN	15	35,917,162 (GRCm38)	missense	probably damaging	1.00
IGL02550:Vps13b	APN	15	35,572,096 (GRCm38)	missense	probably benign
IGL02553:Vps13b	APN	15	35,646,301 (GRCm38)	missense	probably benign	0.00
IGL02674:Vps13b	APN	15	35,639,958 (GRCm38)	missense	probably benign	0.41
IGL02690:Vps13b	APN	15	35,917,142 (GRCm38)	missense	probably damaging	1.00
IGL02731:Vps13b	APN	15	35,917,128 (GRCm38)	missense	probably benign	0.00
IGL02739:Vps13b	APN	15	35,879,900 (GRCm38)	missense	probably damaging	1.00
IGL02868:Vps13b	APN	15	35,884,519 (GRCm38)	missense	probably benign	0.03
IGL03081:Vps13b	APN	15	35,875,820 (GRCm38)	missense	probably damaging	0.97
IGL03178:Vps13b	APN	15	35,869,300 (GRCm38)	missense	probably damaging	1.00
IGL03343:Vps13b	APN	15	35,917,170 (GRCm38)	missense	possibly damaging	0.76
IGL03407:Vps13b	APN	15	35,639,866 (GRCm38)	missense	possibly damaging	0.95
IGL03410:Vps13b	APN	15	35,910,340 (GRCm38)	missense	probably benign
omlette	UTSW	15	35,671,400 (GRCm38)	missense	probably benign	0.13
swiss	UTSW	15	35,709,673 (GRCm38)	missense	possibly damaging	0.80
FR4449:Vps13b	UTSW	15	35,846,957 (GRCm38)	missense	probably damaging	1.00
FR4548:Vps13b	UTSW	15	35,846,957 (GRCm38)	missense	probably damaging	1.00
FR4737:Vps13b	UTSW	15	35,846,957 (GRCm38)	missense	probably damaging	1.00
FR4976:Vps13b	UTSW	15	35,846,957 (GRCm38)	missense	probably damaging	1.00
LCD18:Vps13b	UTSW	15	35,846,957 (GRCm38)	missense	probably damaging	1.00
PIT4531001:Vps13b	UTSW	15	35,878,825 (GRCm38)	missense	probably damaging	1.00
PIT4581001:Vps13b	UTSW	15	35,534,263 (GRCm38)	missense	probably damaging	1.00
R0026:Vps13b	UTSW	15	35,923,301 (GRCm38)	missense	possibly damaging	0.62
R0026:Vps13b	UTSW	15	35,923,301 (GRCm38)	missense	possibly damaging	0.62
R0108:Vps13b	UTSW	15	35,572,119 (GRCm38)	missense	probably benign	0.20
R0109:Vps13b	UTSW	15	35,572,119 (GRCm38)	missense	probably benign	0.20
R0109:Vps13b	UTSW	15	35,572,119 (GRCm38)	missense	probably benign	0.20
R0116:Vps13b	UTSW	15	35,423,155 (GRCm38)	missense	probably damaging	0.99
R0123:Vps13b	UTSW	15	35,887,261 (GRCm38)	missense	probably benign	0.01
R0124:Vps13b	UTSW	15	35,576,528 (GRCm38)	critical splice donor site	probably null
R0134:Vps13b	UTSW	15	35,887,261 (GRCm38)	missense	probably benign	0.01
R0137:Vps13b	UTSW	15	35,926,219 (GRCm38)	missense	probably benign	0.06
R0195:Vps13b	UTSW	15	35,471,899 (GRCm38)	missense	probably benign	0.00
R0225:Vps13b	UTSW	15	35,887,261 (GRCm38)	missense	probably benign	0.01
R0320:Vps13b	UTSW	15	35,674,828 (GRCm38)	missense	probably damaging	0.98
R0333:Vps13b	UTSW	15	35,879,803 (GRCm38)	missense	probably damaging	1.00
R0336:Vps13b	UTSW	15	35,455,133 (GRCm38)	nonsense	probably null
R0463:Vps13b	UTSW	15	35,597,409 (GRCm38)	missense	probably damaging	0.98
R0466:Vps13b	UTSW	15	35,445,602 (GRCm38)	nonsense	probably null
R0472:Vps13b	UTSW	15	35,417,633 (GRCm38)	critical splice donor site	probably null
R0523:Vps13b	UTSW	15	35,472,050 (GRCm38)	missense	probably benign	0.20
R0602:Vps13b	UTSW	15	35,422,368 (GRCm38)	missense	probably damaging	1.00
R0612:Vps13b	UTSW	15	35,623,657 (GRCm38)	missense	probably benign	0.12
R0627:Vps13b	UTSW	15	35,371,999 (GRCm38)	nonsense	probably null
R0679:Vps13b	UTSW	15	35,709,703 (GRCm38)	missense	possibly damaging	0.73
R0742:Vps13b	UTSW	15	35,794,361 (GRCm38)	missense	probably benign	0.22
R1053:Vps13b	UTSW	15	35,652,363 (GRCm38)	missense	probably damaging	1.00
R1355:Vps13b	UTSW	15	35,422,454 (GRCm38)	missense	probably damaging	1.00
R1386:Vps13b	UTSW	15	35,923,312 (GRCm38)	missense	probably damaging	0.99
R1403:Vps13b	UTSW	15	35,709,122 (GRCm38)	splice site	probably benign
R1453:Vps13b	UTSW	15	35,422,444 (GRCm38)	missense	probably damaging	0.97
R1464:Vps13b	UTSW	15	35,709,484 (GRCm38)	missense	probably benign	0.14
R1464:Vps13b	UTSW	15	35,709,484 (GRCm38)	missense	probably benign	0.14
R1511:Vps13b	UTSW	15	35,841,573 (GRCm38)	missense	probably benign	0.00
R1511:Vps13b	UTSW	15	35,839,975 (GRCm38)	missense	probably damaging	0.99
R1513:Vps13b	UTSW	15	35,438,730 (GRCm38)	nonsense	probably null
R1536:Vps13b	UTSW	15	35,875,566 (GRCm38)	missense	probably damaging	0.98
R1537:Vps13b	UTSW	15	35,792,181 (GRCm38)	missense	possibly damaging	0.62
R1558:Vps13b	UTSW	15	35,534,319 (GRCm38)	missense	probably damaging	1.00
R1601:Vps13b	UTSW	15	35,642,436 (GRCm38)	missense	probably benign	0.11
R1653:Vps13b	UTSW	15	35,607,272 (GRCm38)	nonsense	probably null
R1695:Vps13b	UTSW	15	35,576,521 (GRCm38)	missense	probably benign	0.05
R1760:Vps13b	UTSW	15	35,884,619 (GRCm38)	missense	possibly damaging	0.54
R1785:Vps13b	UTSW	15	35,879,791 (GRCm38)	missense	probably damaging	1.00
R1786:Vps13b	UTSW	15	35,879,791 (GRCm38)	missense	probably damaging	1.00
R1803:Vps13b	UTSW	15	35,430,205 (GRCm38)	nonsense	probably null
R1804:Vps13b	UTSW	15	35,917,137 (GRCm38)	missense	probably damaging	1.00
R1808:Vps13b	UTSW	15	35,792,059 (GRCm38)	missense	probably benign	0.00
R1817:Vps13b	UTSW	15	35,910,642 (GRCm38)	missense	possibly damaging	0.86
R1818:Vps13b	UTSW	15	35,877,577 (GRCm38)	missense	probably benign	0.00
R1836:Vps13b	UTSW	15	35,910,232 (GRCm38)	missense	probably damaging	0.99
R1850:Vps13b	UTSW	15	35,674,959 (GRCm38)	splice site	probably benign
R1884:Vps13b	UTSW	15	35,430,291 (GRCm38)	splice site	probably benign
R1938:Vps13b	UTSW	15	35,709,507 (GRCm38)	missense	probably damaging	1.00
R1955:Vps13b	UTSW	15	35,925,408 (GRCm38)	critical splice donor site	probably null
R1956:Vps13b	UTSW	15	35,869,407 (GRCm38)	missense	probably damaging	1.00
R1958:Vps13b	UTSW	15	35,878,689 (GRCm38)	missense	probably damaging	0.99
R2013:Vps13b	UTSW	15	35,607,142 (GRCm38)	missense	probably damaging	0.99
R2014:Vps13b	UTSW	15	35,607,142 (GRCm38)	missense	probably damaging	0.99
R2015:Vps13b	UTSW	15	35,607,142 (GRCm38)	missense	probably damaging	0.99
R2038:Vps13b	UTSW	15	35,884,741 (GRCm38)	missense	probably damaging	1.00
R2058:Vps13b	UTSW	15	35,841,447 (GRCm38)	missense	probably damaging	1.00
R2082:Vps13b	UTSW	15	35,910,746 (GRCm38)	missense	possibly damaging	0.70
R2087:Vps13b	UTSW	15	35,597,493 (GRCm38)	missense	probably damaging	0.99
R2124:Vps13b	UTSW	15	35,646,080 (GRCm38)	missense	probably benign	0.08
R2130:Vps13b	UTSW	15	35,671,400 (GRCm38)	missense	probably benign	0.13
R2168:Vps13b	UTSW	15	35,792,188 (GRCm38)	missense	probably damaging	1.00
R2168:Vps13b	UTSW	15	35,792,189 (GRCm38)	missense	probably damaging	1.00
R2171:Vps13b	UTSW	15	35,887,197 (GRCm38)	missense	probably benign	0.44
R2221:Vps13b	UTSW	15	35,884,597 (GRCm38)	missense	probably benign
R2263:Vps13b	UTSW	15	35,646,181 (GRCm38)	missense	probably benign	0.02
R2289:Vps13b	UTSW	15	35,572,105 (GRCm38)	missense	probably damaging	1.00
R2316:Vps13b	UTSW	15	35,674,899 (GRCm38)	nonsense	probably null
R2351:Vps13b	UTSW	15	35,869,311 (GRCm38)	missense	probably damaging	1.00
R2512:Vps13b	UTSW	15	35,884,555 (GRCm38)	missense	probably benign	0.35
R3054:Vps13b	UTSW	15	35,646,361 (GRCm38)	missense	probably damaging	0.99
R3055:Vps13b	UTSW	15	35,646,361 (GRCm38)	missense	probably damaging	0.99
R3196:Vps13b	UTSW	15	35,869,395 (GRCm38)	missense	probably damaging	1.00
R3236:Vps13b	UTSW	15	35,910,304 (GRCm38)	missense	probably benign	0.40
R3404:Vps13b	UTSW	15	35,926,054 (GRCm38)	missense	probably damaging	1.00
R3722:Vps13b	UTSW	15	35,671,382 (GRCm38)	missense	probably damaging	0.99
R4077:Vps13b	UTSW	15	35,455,128 (GRCm38)	missense	probably damaging	0.99
R4153:Vps13b	UTSW	15	35,792,027 (GRCm38)	splice site	probably null
R4224:Vps13b	UTSW	15	35,876,419 (GRCm38)	missense	probably damaging	0.99
R4408:Vps13b	UTSW	15	35,709,294 (GRCm38)	missense	probably damaging	0.98
R4431:Vps13b	UTSW	15	35,770,753 (GRCm38)	missense	probably damaging	1.00
R4449:Vps13b	UTSW	15	35,876,793 (GRCm38)	missense	possibly damaging	0.86
R4508:Vps13b	UTSW	15	35,709,673 (GRCm38)	missense	possibly damaging	0.80
R4631:Vps13b	UTSW	15	35,646,132 (GRCm38)	missense	possibly damaging	0.95
R4655:Vps13b	UTSW	15	35,770,689 (GRCm38)	missense	probably benign
R4666:Vps13b	UTSW	15	35,640,544 (GRCm38)	missense	probably benign	0.13
R4684:Vps13b	UTSW	15	35,879,821 (GRCm38)	missense	probably benign
R4684:Vps13b	UTSW	15	35,841,341 (GRCm38)	missense	probably benign
R4684:Vps13b	UTSW	15	35,646,178 (GRCm38)	missense	probably damaging	0.98
R4721:Vps13b	UTSW	15	35,910,718 (GRCm38)	nonsense	probably null
R4771:Vps13b	UTSW	15	35,910,800 (GRCm38)	missense	probably damaging	1.00
R4830:Vps13b	UTSW	15	35,452,224 (GRCm38)	missense	possibly damaging	0.94
R4835:Vps13b	UTSW	15	35,869,372 (GRCm38)	missense	probably damaging	1.00
R4835:Vps13b	UTSW	15	35,910,293 (GRCm38)	missense	probably benign
R4857:Vps13b	UTSW	15	35,456,654 (GRCm38)	missense	probably benign	0.01
R4891:Vps13b	UTSW	15	35,640,515 (GRCm38)	splice site	probably null
R5095:Vps13b	UTSW	15	35,923,202 (GRCm38)	missense	probably damaging	1.00
R5110:Vps13b	UTSW	15	35,770,809 (GRCm38)	missense	probably damaging	0.99
R5147:Vps13b	UTSW	15	35,456,678 (GRCm38)	missense	probably benign	0.32
R5153:Vps13b	UTSW	15	35,422,453 (GRCm38)	missense	probably damaging	0.99
R5257:Vps13b	UTSW	15	35,794,421 (GRCm38)	missense	possibly damaging	0.75
R5258:Vps13b	UTSW	15	35,794,421 (GRCm38)	missense	possibly damaging	0.75
R5296:Vps13b	UTSW	15	35,876,413 (GRCm38)	missense	probably damaging	1.00
R5386:Vps13b	UTSW	15	35,640,528 (GRCm38)	critical splice acceptor site	probably null
R5396:Vps13b	UTSW	15	35,886,948 (GRCm38)	missense	probably damaging	0.99
R5412:Vps13b	UTSW	15	35,533,385 (GRCm38)	missense	probably damaging	1.00
R5488:Vps13b	UTSW	15	35,770,542 (GRCm38)	missense	probably benign
R5489:Vps13b	UTSW	15	35,770,542 (GRCm38)	missense	probably benign
R5503:Vps13b	UTSW	15	35,452,166 (GRCm38)	missense	probably damaging	0.97
R5575:Vps13b	UTSW	15	35,929,919 (GRCm38)	missense	probably damaging	1.00
R5781:Vps13b	UTSW	15	35,794,035 (GRCm38)	missense	probably damaging	0.97
R5872:Vps13b	UTSW	15	35,869,351 (GRCm38)	missense	possibly damaging	0.56
R5876:Vps13b	UTSW	15	35,917,061 (GRCm38)	missense	probably damaging	0.99
R5994:Vps13b	UTSW	15	35,875,772 (GRCm38)	missense	probably damaging	1.00
R6031:Vps13b	UTSW	15	35,471,968 (GRCm38)	missense	probably damaging	1.00
R6031:Vps13b	UTSW	15	35,471,968 (GRCm38)	missense	probably damaging	1.00
R6045:Vps13b	UTSW	15	35,671,316 (GRCm38)	missense	probably damaging	0.99
R6143:Vps13b	UTSW	15	35,668,738 (GRCm38)	missense	probably damaging	0.99
R6147:Vps13b	UTSW	15	35,930,031 (GRCm38)	missense	probably benign	0.16
R6218:Vps13b	UTSW	15	35,770,464 (GRCm38)	missense	probably benign	0.00
R6447:Vps13b	UTSW	15	35,572,126 (GRCm38)	missense	probably benign	0.02
R6555:Vps13b	UTSW	15	35,846,847 (GRCm38)	missense	probably damaging	1.00
R6578:Vps13b	UTSW	15	35,446,101 (GRCm38)	missense	probably damaging	0.99
R6640:Vps13b	UTSW	15	35,617,696 (GRCm38)	missense	possibly damaging	0.93
R6645:Vps13b	UTSW	15	35,910,305 (GRCm38)	missense	probably benign	0.25
R6711:Vps13b	UTSW	15	35,887,249 (GRCm38)	missense	probably damaging	1.00
R6727:Vps13b	UTSW	15	35,770,683 (GRCm38)	missense	probably benign	0.19
R6737:Vps13b	UTSW	15	35,910,611 (GRCm38)	missense	probably damaging	1.00
R6844:Vps13b	UTSW	15	35,877,590 (GRCm38)	missense	probably benign	0.06
R6849:Vps13b	UTSW	15	35,905,309 (GRCm38)	missense	probably damaging	1.00
R6861:Vps13b	UTSW	15	35,576,395 (GRCm38)	missense	probably damaging	0.99
R6938:Vps13b	UTSW	15	35,423,198 (GRCm38)	missense	probably damaging	0.99
R6943:Vps13b	UTSW	15	35,448,689 (GRCm38)	missense	possibly damaging	0.95
R6989:Vps13b	UTSW	15	35,448,581 (GRCm38)	missense	probably benign	0.02
R7092:Vps13b	UTSW	15	35,640,634 (GRCm38)	missense	probably damaging	1.00
R7232:Vps13b	UTSW	15	35,877,557 (GRCm38)	missense	probably damaging	1.00
R7307:Vps13b	UTSW	15	35,841,545 (GRCm38)	missense	probably benign
R7400:Vps13b	UTSW	15	35,378,900 (GRCm38)	missense	probably damaging	1.00
R7414:Vps13b	UTSW	15	35,910,827 (GRCm38)	missense	probably damaging	1.00
R7497:Vps13b	UTSW	15	35,876,697 (GRCm38)	missense	probably benign	0.38
R7500:Vps13b	UTSW	15	35,910,524 (GRCm38)	missense	possibly damaging	0.74
R7603:Vps13b	UTSW	15	35,576,439 (GRCm38)	missense	probably damaging	0.98
R7605:Vps13b	UTSW	15	35,770,646 (GRCm38)	missense	probably damaging	0.97
R7849:Vps13b	UTSW	15	35,423,232 (GRCm38)	missense	probably damaging	0.99
R7984:Vps13b	UTSW	15	35,879,913 (GRCm38)	missense	probably benign
R8094:Vps13b	UTSW	15	35,668,906 (GRCm38)	critical splice donor site	probably null
R8097:Vps13b	UTSW	15	35,709,346 (GRCm38)	missense	probably benign	0.38
R8131:Vps13b	UTSW	15	35,372,109 (GRCm38)	critical splice donor site	probably null
R8139:Vps13b	UTSW	15	35,607,272 (GRCm38)	nonsense	probably null
R8174:Vps13b	UTSW	15	35,709,310 (GRCm38)	nonsense	probably null
R8225:Vps13b	UTSW	15	35,794,382 (GRCm38)	missense	probably damaging	0.99
R8239:Vps13b	UTSW	15	35,597,404 (GRCm38)	missense	probably damaging	1.00
R8244:Vps13b	UTSW	15	35,917,203 (GRCm38)	missense	probably damaging	1.00
R8303:Vps13b	UTSW	15	35,639,917 (GRCm38)	missense	probably damaging	1.00
R8311:Vps13b	UTSW	15	35,886,954 (GRCm38)	missense	probably benign	0.37
R8443:Vps13b	UTSW	15	35,455,100 (GRCm38)	missense	probably benign
R8494:Vps13b	UTSW	15	35,422,448 (GRCm38)	missense	probably damaging	0.99
R8499:Vps13b	UTSW	15	35,841,320 (GRCm38)	missense	probably damaging	1.00
R8506:Vps13b	UTSW	15	35,446,745 (GRCm38)	missense	probably benign	0.31
R8559:Vps13b	UTSW	15	35,876,642 (GRCm38)	missense	probably damaging	1.00
R8686:Vps13b	UTSW	15	35,925,389 (GRCm38)	missense	probably damaging	0.99
R8782:Vps13b	UTSW	15	35,422,337 (GRCm38)	missense	possibly damaging	0.93
R8806:Vps13b	UTSW	15	35,472,066 (GRCm38)	critical splice donor site	probably benign
R8824:Vps13b	UTSW	15	35,533,299 (GRCm38)	missense	probably damaging	0.99
R9024:Vps13b	UTSW	15	35,923,324 (GRCm38)	missense	probably damaging	0.97
R9038:Vps13b	UTSW	15	35,875,785 (GRCm38)	missense	possibly damaging	0.70
R9054:Vps13b	UTSW	15	35,422,391 (GRCm38)	missense	probably damaging	1.00
R9091:Vps13b	UTSW	15	35,770,773 (GRCm38)	missense	probably benign	0.13
R9129:Vps13b	UTSW	15	35,448,647 (GRCm38)	missense	probably damaging	1.00
R9214:Vps13b	UTSW	15	35,623,746 (GRCm38)	missense	probably damaging	0.99
R9237:Vps13b	UTSW	15	35,841,333 (GRCm38)	missense	probably damaging	1.00
R9256:Vps13b	UTSW	15	35,623,779 (GRCm38)	missense	possibly damaging	0.95
R9270:Vps13b	UTSW	15	35,770,773 (GRCm38)	missense	probably benign	0.13
R9279:Vps13b	UTSW	15	35,572,144 (GRCm38)	missense	probably damaging	0.97
R9291:Vps13b	UTSW	15	35,846,913 (GRCm38)	missense	probably damaging	1.00
R9342:Vps13b	UTSW	15	35,455,054 (GRCm38)	missense	possibly damaging	0.94
R9404:Vps13b	UTSW	15	35,876,419 (GRCm38)	missense	probably damaging	1.00
R9488:Vps13b	UTSW	15	35,447,734 (GRCm38)	missense	possibly damaging	0.77
R9509:Vps13b	UTSW	15	35,841,311 (GRCm38)	missense	possibly damaging	0.79
R9610:Vps13b	UTSW	15	35,642,409 (GRCm38)	missense	possibly damaging	0.85
R9611:Vps13b	UTSW	15	35,642,409 (GRCm38)	missense	possibly damaging	0.85
R9658:Vps13b	UTSW	15	35,623,628 (GRCm38)	missense	probably benign	0.00
R9674:Vps13b	UTSW	15	35,607,234 (GRCm38)	missense	probably damaging	0.98
R9696:Vps13b	UTSW	15	35,674,887 (GRCm38)	missense	possibly damaging	0.56
R9767:Vps13b	UTSW	15	35,910,257 (GRCm38)	missense	probably damaging	1.00
R9797:Vps13b	UTSW	15	35,674,876 (GRCm38)	missense	probably damaging	1.00
RF020:Vps13b	UTSW	15	35,925,406 (GRCm38)	missense	probably null	1.00
X0026:Vps13b	UTSW	15	35,910,646 (GRCm38)	missense	probably damaging	1.00
X0028:Vps13b	UTSW	15	35,709,431 (GRCm38)	missense	probably benign	0.00
Z1177:Vps13b	UTSW	15	35,668,885 (GRCm38)	nonsense	probably null

Predicted Primers

PCR Primer
(F):5'- TTCATGTAGGGACACTTGATGC -3'
(R):5'- TCTGCGAGATTTAAGAAAGTCCTGC -3'

Sequencing Primer
(F):5'- CATGTAGGGACACTTGATGCATAAC -3'
(R):5'- AAGAAAGTCCTGCCTGTTTTCC -3'

Posted On

2019-06-07