Incidental Mutation 'PIT4469001:Mast4'
ID | 555838 |
Institutional Source |
Beutler Lab
|
Gene Symbol |
Mast4
|
Ensembl Gene |
ENSMUSG00000034751 |
Gene Name | microtubule associated serine/threonine kinase family member 4 |
Synonyms | 4930420O11Rik |
Accession Numbers |
Genbank: NM_175171.3; EnsemblENSMUST00000167058 , ENSMUST00000167462, ENSMUST00000166726, ENSMUST00000164111 , ENSMUST00000166336, ENSMUST00000099202, ENSMUST00000172264, ENSMUST00000171791, ENSMUST00000091273
|
Is this an essential gene? |
Possibly non essential (E-score: 0.298)
|
Stock # | PIT4469001 (G1)
|
Quality Score | 224.009 |
Status |
Not validated
|
Chromosome | 13 |
Chromosomal Location | 102732486-103334497 bp(-) (GRCm38) |
Type of Mutation | missense |
DNA Base Change (assembly) |
G to A
at 102804718 bp
|
Zygosity | Heterozygous |
Amino Acid Change |
Threonine to Methionine
at position 277
(T277M)
|
Ref Sequence |
ENSEMBL: ENSMUSP00000128464
(fasta)
|
Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000099202]
[ENSMUST00000166336]
[ENSMUST00000166726]
[ENSMUST00000167058]
[ENSMUST00000167462]
[ENSMUST00000171791]
[ENSMUST00000172264]
|
Predicted Effect |
probably damaging
Transcript: ENSMUST00000099202
AA Change: T100M
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
SMART Domains |
Protein: ENSMUSP00000096808 Gene: ENSMUSG00000034751 AA Change: T100M
Domain | Start | End | E-Value | Type |
low complexity region
|
13 |
38 |
N/A |
INTRINSIC |
Pfam:DUF1908
|
76 |
353 |
2.2e-146 |
PFAM |
S_TKc
|
391 |
664 |
4.13e-98 |
SMART |
S_TK_X
|
665 |
729 |
3.79e-2 |
SMART |
low complexity region
|
745 |
758 |
N/A |
INTRINSIC |
low complexity region
|
818 |
831 |
N/A |
INTRINSIC |
low complexity region
|
840 |
857 |
N/A |
INTRINSIC |
low complexity region
|
925 |
960 |
N/A |
INTRINSIC |
PDZ
|
970 |
1050 |
2.34e-15 |
SMART |
low complexity region
|
1070 |
1087 |
N/A |
INTRINSIC |
low complexity region
|
1111 |
1122 |
N/A |
INTRINSIC |
low complexity region
|
1127 |
1139 |
N/A |
INTRINSIC |
low complexity region
|
1142 |
1164 |
N/A |
INTRINSIC |
low complexity region
|
1202 |
1219 |
N/A |
INTRINSIC |
low complexity region
|
1290 |
1306 |
N/A |
INTRINSIC |
low complexity region
|
1345 |
1361 |
N/A |
INTRINSIC |
low complexity region
|
1937 |
1953 |
N/A |
INTRINSIC |
low complexity region
|
1996 |
2010 |
N/A |
INTRINSIC |
low complexity region
|
2150 |
2161 |
N/A |
INTRINSIC |
low complexity region
|
2296 |
2307 |
N/A |
INTRINSIC |
|
Predicted Effect |
probably damaging
Transcript: ENSMUST00000166336
AA Change: T92M
PolyPhen 2
Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)
|
SMART Domains |
Protein: ENSMUSP00000126516 Gene: ENSMUSG00000034751 AA Change: T92M
Domain | Start | End | E-Value | Type |
Pfam:DUF1908
|
71 |
212 |
1.2e-68 |
PFAM |
|
Predicted Effect |
probably damaging
Transcript: ENSMUST00000166726
AA Change: T277M
PolyPhen 2
Score 0.998 (Sensitivity: 0.27; Specificity: 0.99)
|
SMART Domains |
Protein: ENSMUSP00000132263 Gene: ENSMUSG00000034751 AA Change: T277M
Domain | Start | End | E-Value | Type |
low complexity region
|
23 |
51 |
N/A |
INTRINSIC |
Pfam:DUF1908
|
256 |
530 |
4.2e-145 |
PFAM |
S_TKc
|
568 |
841 |
4.13e-98 |
SMART |
S_TK_X
|
842 |
906 |
3.79e-2 |
SMART |
low complexity region
|
922 |
935 |
N/A |
INTRINSIC |
low complexity region
|
995 |
1008 |
N/A |
INTRINSIC |
low complexity region
|
1035 |
1070 |
N/A |
INTRINSIC |
PDZ
|
1080 |
1160 |
2.34e-15 |
SMART |
low complexity region
|
1180 |
1201 |
N/A |
INTRINSIC |
|
Predicted Effect |
probably damaging
Transcript: ENSMUST00000167058
AA Change: T277M
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
SMART Domains |
Protein: ENSMUSP00000128464 Gene: ENSMUSG00000034751 AA Change: T277M
Domain | Start | End | E-Value | Type |
low complexity region
|
23 |
51 |
N/A |
INTRINSIC |
Pfam:DUF1908
|
256 |
529 |
5.1e-134 |
PFAM |
S_TKc
|
568 |
841 |
4.13e-98 |
SMART |
S_TK_X
|
842 |
906 |
3.79e-2 |
SMART |
low complexity region
|
922 |
935 |
N/A |
INTRINSIC |
low complexity region
|
995 |
1008 |
N/A |
INTRINSIC |
low complexity region
|
1017 |
1034 |
N/A |
INTRINSIC |
low complexity region
|
1102 |
1137 |
N/A |
INTRINSIC |
PDZ
|
1147 |
1227 |
2.34e-15 |
SMART |
low complexity region
|
1247 |
1264 |
N/A |
INTRINSIC |
low complexity region
|
1288 |
1299 |
N/A |
INTRINSIC |
low complexity region
|
1304 |
1316 |
N/A |
INTRINSIC |
low complexity region
|
1319 |
1341 |
N/A |
INTRINSIC |
low complexity region
|
1379 |
1396 |
N/A |
INTRINSIC |
low complexity region
|
1467 |
1483 |
N/A |
INTRINSIC |
low complexity region
|
1522 |
1538 |
N/A |
INTRINSIC |
low complexity region
|
2114 |
2130 |
N/A |
INTRINSIC |
low complexity region
|
2173 |
2187 |
N/A |
INTRINSIC |
low complexity region
|
2327 |
2338 |
N/A |
INTRINSIC |
low complexity region
|
2473 |
2484 |
N/A |
INTRINSIC |
|
Predicted Effect |
probably damaging
Transcript: ENSMUST00000167462
AA Change: T85M
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
SMART Domains |
Protein: ENSMUSP00000131910 Gene: ENSMUSG00000034751 AA Change: T85M
Domain | Start | End | E-Value | Type |
Pfam:DUF1908
|
64 |
338 |
3e-145 |
PFAM |
S_TKc
|
376 |
649 |
4.13e-98 |
SMART |
S_TK_X
|
650 |
714 |
3.79e-2 |
SMART |
low complexity region
|
730 |
743 |
N/A |
INTRINSIC |
low complexity region
|
803 |
816 |
N/A |
INTRINSIC |
low complexity region
|
843 |
878 |
N/A |
INTRINSIC |
PDZ
|
888 |
968 |
2.34e-15 |
SMART |
|
Predicted Effect |
probably damaging
Transcript: ENSMUST00000171791
AA Change: T85M
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
SMART Domains |
Protein: ENSMUSP00000131651 Gene: ENSMUSG00000034751 AA Change: T85M
Domain | Start | End | E-Value | Type |
Pfam:DUF1908
|
64 |
338 |
1.2e-144 |
PFAM |
S_TKc
|
376 |
649 |
4.13e-98 |
SMART |
S_TK_X
|
650 |
714 |
3.79e-2 |
SMART |
low complexity region
|
730 |
743 |
N/A |
INTRINSIC |
low complexity region
|
803 |
816 |
N/A |
INTRINSIC |
low complexity region
|
825 |
842 |
N/A |
INTRINSIC |
low complexity region
|
910 |
945 |
N/A |
INTRINSIC |
PDZ
|
955 |
1035 |
2.34e-15 |
SMART |
low complexity region
|
1055 |
1072 |
N/A |
INTRINSIC |
low complexity region
|
1096 |
1107 |
N/A |
INTRINSIC |
low complexity region
|
1112 |
1124 |
N/A |
INTRINSIC |
low complexity region
|
1127 |
1149 |
N/A |
INTRINSIC |
low complexity region
|
1187 |
1204 |
N/A |
INTRINSIC |
low complexity region
|
1275 |
1291 |
N/A |
INTRINSIC |
low complexity region
|
1330 |
1346 |
N/A |
INTRINSIC |
low complexity region
|
1922 |
1938 |
N/A |
INTRINSIC |
low complexity region
|
1981 |
1995 |
N/A |
INTRINSIC |
low complexity region
|
2135 |
2146 |
N/A |
INTRINSIC |
low complexity region
|
2281 |
2292 |
N/A |
INTRINSIC |
|
Predicted Effect |
probably damaging
Transcript: ENSMUST00000172264
AA Change: T73M
PolyPhen 2
Score 0.996 (Sensitivity: 0.55; Specificity: 0.98)
|
SMART Domains |
Protein: ENSMUSP00000128129 Gene: ENSMUSG00000034751 AA Change: T73M
Domain | Start | End | E-Value | Type |
Pfam:DUF1908
|
49 |
326 |
4.1e-147 |
PFAM |
S_TKc
|
364 |
637 |
4.13e-98 |
SMART |
S_TK_X
|
638 |
702 |
3.79e-2 |
SMART |
low complexity region
|
718 |
731 |
N/A |
INTRINSIC |
low complexity region
|
791 |
804 |
N/A |
INTRINSIC |
low complexity region
|
813 |
830 |
N/A |
INTRINSIC |
|
Predicted Effect |
|
Coding Region Coverage |
- 1x: 93.3%
- 3x: 90.7%
- 10x: 84.4%
- 20x: 71.1%
|
Validation Efficiency |
|
MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a member of the microtubule-associated serine/threonine protein kinases. The proteins in this family contain a domain that gives the kinase the ability to determine its own scaffold to control the effects of their kinase activities. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2014] PHENOTYPE: Mice homozygous for an ENU-induced allele exhibit malocclusion. [provided by MGI curators]
|
Allele List at MGI |
All alleles(8) : Gene trapped(8)
|
Other mutations in this stock |
Total: 29 list
Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
6030408B16Rik |
T |
C |
15: 101,293,271 |
V6A |
probably benign |
Het |
A630001G21Rik |
A |
G |
1: 85,725,199 |
F83L |
probably benign |
Het |
Acsm2 |
T |
A |
7: 119,578,185 |
C308S |
possibly damaging |
Het |
Ak3 |
A |
G |
19: 29,047,757 |
S25P |
probably damaging |
Het |
Atp13a2 |
T |
A |
4: 140,994,127 |
V176E |
unknown |
Het |
Bmper |
A |
T |
9: 23,406,549 |
H488L |
probably benign |
Het |
Cacna1c |
A |
T |
6: 118,595,972 |
C2084S |
unknown |
Het |
Ccp110 |
T |
A |
7: 118,722,377 |
N418K |
probably benign |
Het |
Ddx17 |
C |
A |
15: 79,543,813 |
G32C |
probably damaging |
Het |
Dusp16 |
G |
A |
6: 134,761,152 |
|
probably benign |
Het |
Efl1 |
T |
G |
7: 82,658,165 |
F90V |
probably benign |
Het |
Ell2 |
T |
A |
13: 75,761,892 |
N252K |
probably damaging |
Het |
Gdf6 |
T |
C |
4: 9,859,569 |
V217A |
probably damaging |
Het |
Gm6205 |
T |
A |
5: 94,682,793 |
V50E |
probably damaging |
Het |
Hint1 |
T |
A |
11: 54,870,070 |
S112T |
unknown |
Het |
Hist1h1e |
A |
T |
13: 23,622,379 |
V40E |
probably damaging |
Het |
Kif5c |
T |
C |
2: 49,741,348 |
V679A |
probably benign |
Het |
Lrrn3 |
A |
T |
12: 41,453,018 |
D433E |
probably benign |
Het |
Naa11 |
A |
G |
5: 97,391,626 |
|
probably null |
Het |
Pcdh18 |
T |
A |
3: 49,755,069 |
H599L |
probably benign |
Het |
Pgc |
A |
T |
17: 47,728,755 |
K25* |
probably null |
Het |
Psd4 |
G |
A |
2: 24,394,294 |
D57N |
probably benign |
Het |
Pxdn |
G |
A |
12: 30,005,829 |
R1238Q |
probably benign |
Het |
Spata32 |
T |
C |
11: 103,209,827 |
N38S |
probably benign |
Het |
St5 |
G |
A |
7: 109,531,130 |
A888V |
probably damaging |
Het |
Tpr |
A |
G |
1: 150,403,956 |
T279A |
probably benign |
Het |
Unc13a |
C |
A |
8: 71,658,314 |
E418* |
probably null |
Het |
Vmn2r97 |
C |
A |
17: 18,929,616 |
T422K |
probably benign |
Het |
Zfp474 |
A |
T |
18: 52,638,719 |
Q148L |
possibly damaging |
Het |
|
Other mutations in Mast4 |
Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
IGL00703:Mast4
|
APN |
13 |
102770767 |
nonsense |
probably null |
|
IGL00933:Mast4
|
APN |
13 |
102735366 |
missense |
probably damaging |
0.97 |
IGL01113:Mast4
|
APN |
13 |
102774236 |
missense |
probably damaging |
1.00 |
IGL01461:Mast4
|
APN |
13 |
102754068 |
missense |
probably damaging |
1.00 |
IGL01569:Mast4
|
APN |
13 |
102761015 |
missense |
probably damaging |
1.00 |
IGL01697:Mast4
|
APN |
13 |
102767893 |
missense |
probably damaging |
1.00 |
IGL01725:Mast4
|
APN |
13 |
102750512 |
critical splice donor site |
probably null |
|
IGL01734:Mast4
|
APN |
13 |
102737615 |
missense |
probably damaging |
0.98 |
IGL01738:Mast4
|
APN |
13 |
102737241 |
missense |
probably damaging |
1.00 |
IGL01739:Mast4
|
APN |
13 |
102774273 |
missense |
probably damaging |
1.00 |
IGL02299:Mast4
|
APN |
13 |
102737974 |
missense |
probably benign |
0.44 |
IGL02479:Mast4
|
APN |
13 |
102742037 |
missense |
probably damaging |
1.00 |
IGL02485:Mast4
|
APN |
13 |
102735496 |
missense |
probably benign |
0.02 |
IGL02528:Mast4
|
APN |
13 |
102853823 |
makesense |
probably null |
|
IGL02850:Mast4
|
APN |
13 |
102754232 |
missense |
probably damaging |
1.00 |
IGL02900:Mast4
|
APN |
13 |
102735676 |
missense |
probably benign |
|
IGL03064:Mast4
|
APN |
13 |
102760964 |
nonsense |
probably null |
|
IGL03124:Mast4
|
APN |
13 |
102738245 |
missense |
probably damaging |
1.00 |
IGL03146:Mast4
|
APN |
13 |
102737655 |
missense |
probably benign |
0.00 |
IGL03221:Mast4
|
APN |
13 |
102754256 |
missense |
possibly damaging |
0.95 |
IGL03284:Mast4
|
APN |
13 |
102751397 |
missense |
probably damaging |
1.00 |
IGL03406:Mast4
|
APN |
13 |
102737107 |
missense |
possibly damaging |
0.46 |
buck
|
UTSW |
13 |
102761293 |
critical splice donor site |
probably null |
|
doe
|
UTSW |
13 |
102905677 |
missense |
possibly damaging |
0.85 |
skinnybones
|
UTSW |
13 |
102804641 |
critical splice donor site |
probably null |
|
BB010:Mast4
|
UTSW |
13 |
102772563 |
missense |
probably damaging |
0.99 |
BB020:Mast4
|
UTSW |
13 |
102772563 |
missense |
probably damaging |
0.99 |
FR4304:Mast4
|
UTSW |
13 |
102734862 |
utr 3 prime |
probably benign |
|
FR4340:Mast4
|
UTSW |
13 |
102734857 |
frame shift |
probably null |
|
FR4340:Mast4
|
UTSW |
13 |
102736317 |
small insertion |
probably benign |
|
FR4548:Mast4
|
UTSW |
13 |
102736318 |
small insertion |
probably benign |
|
FR4976:Mast4
|
UTSW |
13 |
102736312 |
small insertion |
probably benign |
|
FR4976:Mast4
|
UTSW |
13 |
102739247 |
frame shift |
probably null |
|
NA:Mast4
|
UTSW |
13 |
102742057 |
missense |
probably damaging |
1.00 |
PIT4466001:Mast4
|
UTSW |
13 |
102804718 |
missense |
probably damaging |
1.00 |
PIT4472001:Mast4
|
UTSW |
13 |
102804718 |
missense |
probably damaging |
1.00 |
R0009:Mast4
|
UTSW |
13 |
102742058 |
missense |
probably damaging |
1.00 |
R0063:Mast4
|
UTSW |
13 |
103334215 |
start gained |
probably benign |
|
R0242:Mast4
|
UTSW |
13 |
102853842 |
missense |
probably damaging |
1.00 |
R0310:Mast4
|
UTSW |
13 |
102754161 |
missense |
possibly damaging |
0.94 |
R0395:Mast4
|
UTSW |
13 |
102735273 |
missense |
probably damaging |
1.00 |
R0454:Mast4
|
UTSW |
13 |
102751560 |
missense |
probably damaging |
1.00 |
R0646:Mast4
|
UTSW |
13 |
102758744 |
splice site |
probably benign |
|
R0744:Mast4
|
UTSW |
13 |
102737387 |
missense |
probably damaging |
0.98 |
R0883:Mast4
|
UTSW |
13 |
102853900 |
missense |
probably damaging |
1.00 |
R0905:Mast4
|
UTSW |
13 |
102770784 |
missense |
probably damaging |
0.99 |
R1023:Mast4
|
UTSW |
13 |
102735496 |
missense |
probably benign |
0.02 |
R1281:Mast4
|
UTSW |
13 |
102750578 |
missense |
probably damaging |
1.00 |
R1376:Mast4
|
UTSW |
13 |
102736408 |
missense |
possibly damaging |
0.46 |
R1376:Mast4
|
UTSW |
13 |
102736408 |
missense |
possibly damaging |
0.46 |
R1473:Mast4
|
UTSW |
13 |
102772519 |
missense |
probably damaging |
1.00 |
R1572:Mast4
|
UTSW |
13 |
102736923 |
missense |
possibly damaging |
0.51 |
R1575:Mast4
|
UTSW |
13 |
102739263 |
missense |
probably damaging |
1.00 |
R1865:Mast4
|
UTSW |
13 |
102794117 |
missense |
probably damaging |
1.00 |
R2050:Mast4
|
UTSW |
13 |
102751409 |
missense |
probably damaging |
1.00 |
R2060:Mast4
|
UTSW |
13 |
102738846 |
missense |
probably damaging |
1.00 |
R2062:Mast4
|
UTSW |
13 |
102759093 |
missense |
probably benign |
0.18 |
R2106:Mast4
|
UTSW |
13 |
102750546 |
missense |
probably damaging |
1.00 |
R2118:Mast4
|
UTSW |
13 |
102754205 |
missense |
probably damaging |
1.00 |
R2143:Mast4
|
UTSW |
13 |
102735475 |
missense |
possibly damaging |
0.89 |
R2256:Mast4
|
UTSW |
13 |
102735751 |
missense |
possibly damaging |
0.62 |
R2261:Mast4
|
UTSW |
13 |
102798207 |
splice site |
probably benign |
|
R2370:Mast4
|
UTSW |
13 |
102774187 |
missense |
probably damaging |
1.00 |
R2504:Mast4
|
UTSW |
13 |
102738639 |
missense |
probably damaging |
0.96 |
R2509:Mast4
|
UTSW |
13 |
102853842 |
missense |
probably damaging |
1.00 |
R2842:Mast4
|
UTSW |
13 |
102736431 |
missense |
probably benign |
0.01 |
R3087:Mast4
|
UTSW |
13 |
102853926 |
splice site |
probably benign |
|
R3434:Mast4
|
UTSW |
13 |
102787379 |
missense |
probably damaging |
1.00 |
R3435:Mast4
|
UTSW |
13 |
102787379 |
missense |
probably damaging |
1.00 |
R3763:Mast4
|
UTSW |
13 |
102787419 |
missense |
probably damaging |
1.00 |
R3826:Mast4
|
UTSW |
13 |
102738811 |
missense |
probably damaging |
1.00 |
R3829:Mast4
|
UTSW |
13 |
102738811 |
missense |
probably damaging |
1.00 |
R3830:Mast4
|
UTSW |
13 |
102738811 |
missense |
probably damaging |
1.00 |
R3913:Mast4
|
UTSW |
13 |
102758669 |
missense |
probably damaging |
1.00 |
R3914:Mast4
|
UTSW |
13 |
102739321 |
nonsense |
probably null |
|
R4021:Mast4
|
UTSW |
13 |
102739321 |
nonsense |
probably null |
|
R4022:Mast4
|
UTSW |
13 |
102739321 |
nonsense |
probably null |
|
R4022:Mast4
|
UTSW |
13 |
102853869 |
missense |
probably damaging |
1.00 |
R4210:Mast4
|
UTSW |
13 |
102739205 |
missense |
probably damaging |
1.00 |
R4342:Mast4
|
UTSW |
13 |
102774248 |
missense |
probably damaging |
1.00 |
R4580:Mast4
|
UTSW |
13 |
102737258 |
nonsense |
probably null |
|
R4627:Mast4
|
UTSW |
13 |
103334021 |
missense |
possibly damaging |
0.92 |
R4711:Mast4
|
UTSW |
13 |
103334119 |
missense |
probably benign |
0.01 |
R4732:Mast4
|
UTSW |
13 |
102772572 |
missense |
probably damaging |
0.99 |
R4733:Mast4
|
UTSW |
13 |
102772572 |
missense |
probably damaging |
0.99 |
R4833:Mast4
|
UTSW |
13 |
102774184 |
critical splice donor site |
probably null |
|
R4995:Mast4
|
UTSW |
13 |
102905754 |
intron |
probably benign |
|
R5059:Mast4
|
UTSW |
13 |
102750563 |
missense |
probably damaging |
1.00 |
R5073:Mast4
|
UTSW |
13 |
102738883 |
nonsense |
probably null |
|
R5101:Mast4
|
UTSW |
13 |
102736356 |
missense |
probably benign |
0.01 |
R5526:Mast4
|
UTSW |
13 |
102754215 |
missense |
possibly damaging |
0.48 |
R5599:Mast4
|
UTSW |
13 |
102737479 |
missense |
probably damaging |
1.00 |
R5673:Mast4
|
UTSW |
13 |
102794072 |
missense |
probably damaging |
1.00 |
R5694:Mast4
|
UTSW |
13 |
102774193 |
nonsense |
probably null |
|
R5906:Mast4
|
UTSW |
13 |
102735744 |
missense |
probably benign |
0.31 |
R5908:Mast4
|
UTSW |
13 |
102738256 |
missense |
probably damaging |
1.00 |
R5947:Mast4
|
UTSW |
13 |
102735640 |
missense |
probably benign |
|
R5987:Mast4
|
UTSW |
13 |
102758734 |
missense |
probably damaging |
1.00 |
R6143:Mast4
|
UTSW |
13 |
102853883 |
missense |
probably damaging |
1.00 |
R6154:Mast4
|
UTSW |
13 |
102787421 |
missense |
probably damaging |
1.00 |
R6169:Mast4
|
UTSW |
13 |
102787421 |
missense |
probably damaging |
1.00 |
R6239:Mast4
|
UTSW |
13 |
102736209 |
missense |
probably benign |
0.01 |
R6327:Mast4
|
UTSW |
13 |
102761382 |
missense |
probably damaging |
1.00 |
R6356:Mast4
|
UTSW |
13 |
102735985 |
missense |
possibly damaging |
0.80 |
R6432:Mast4
|
UTSW |
13 |
102905677 |
missense |
possibly damaging |
0.85 |
R6522:Mast4
|
UTSW |
13 |
102761293 |
critical splice donor site |
probably null |
|
R6667:Mast4
|
UTSW |
13 |
102737496 |
missense |
probably damaging |
1.00 |
R6941:Mast4
|
UTSW |
13 |
102804714 |
missense |
probably damaging |
1.00 |
R6968:Mast4
|
UTSW |
13 |
102798078 |
missense |
probably damaging |
1.00 |
R6968:Mast4
|
UTSW |
13 |
102804647 |
missense |
probably damaging |
1.00 |
R6970:Mast4
|
UTSW |
13 |
102804647 |
missense |
probably damaging |
1.00 |
R6980:Mast4
|
UTSW |
13 |
102804647 |
missense |
probably damaging |
1.00 |
R6991:Mast4
|
UTSW |
13 |
102804647 |
missense |
probably damaging |
1.00 |
R6992:Mast4
|
UTSW |
13 |
102804647 |
missense |
probably damaging |
1.00 |
R6993:Mast4
|
UTSW |
13 |
102735974 |
missense |
probably benign |
0.28 |
R6993:Mast4
|
UTSW |
13 |
102804647 |
missense |
probably damaging |
1.00 |
R7083:Mast4
|
UTSW |
13 |
102737715 |
missense |
probably damaging |
1.00 |
R7241:Mast4
|
UTSW |
13 |
103334000 |
missense |
possibly damaging |
0.87 |
R7242:Mast4
|
UTSW |
13 |
102738478 |
missense |
probably damaging |
1.00 |
R7246:Mast4
|
UTSW |
13 |
102794003 |
missense |
probably damaging |
1.00 |
R7332:Mast4
|
UTSW |
13 |
102751424 |
missense |
possibly damaging |
0.61 |
R7453:Mast4
|
UTSW |
13 |
102804641 |
critical splice donor site |
probably null |
|
R7514:Mast4
|
UTSW |
13 |
102787426 |
nonsense |
probably null |
|
R7697:Mast4
|
UTSW |
13 |
102739203 |
missense |
probably damaging |
1.00 |
R7820:Mast4
|
UTSW |
13 |
102754088 |
missense |
probably damaging |
1.00 |
R7874:Mast4
|
UTSW |
13 |
102739275 |
missense |
probably damaging |
1.00 |
R7933:Mast4
|
UTSW |
13 |
102772563 |
missense |
probably damaging |
0.99 |
R8042:Mast4
|
UTSW |
13 |
102781245 |
missense |
probably damaging |
0.96 |
R8060:Mast4
|
UTSW |
13 |
102737676 |
missense |
possibly damaging |
0.89 |
R8172:Mast4
|
UTSW |
13 |
102953125 |
critical splice donor site |
probably null |
|
R8206:Mast4
|
UTSW |
13 |
102735739 |
missense |
probably damaging |
1.00 |
R8248:Mast4
|
UTSW |
13 |
102738721 |
missense |
probably damaging |
1.00 |
R8283:Mast4
|
UTSW |
13 |
102758669 |
missense |
probably damaging |
1.00 |
R8346:Mast4
|
UTSW |
13 |
102751478 |
missense |
probably damaging |
0.99 |
R8434:Mast4
|
UTSW |
13 |
102761392 |
missense |
probably damaging |
1.00 |
RF005:Mast4
|
UTSW |
13 |
102736307 |
small insertion |
probably benign |
|
RF015:Mast4
|
UTSW |
13 |
102739247 |
frame shift |
probably null |
|
RF019:Mast4
|
UTSW |
13 |
102736307 |
small insertion |
probably benign |
|
RF037:Mast4
|
UTSW |
13 |
102739241 |
small deletion |
probably benign |
|
RF039:Mast4
|
UTSW |
13 |
102739241 |
small deletion |
probably benign |
|
RF040:Mast4
|
UTSW |
13 |
102739241 |
small deletion |
probably benign |
|
Z1088:Mast4
|
UTSW |
13 |
102738519 |
missense |
probably damaging |
1.00 |
Z1176:Mast4
|
UTSW |
13 |
102738460 |
missense |
probably damaging |
1.00 |
|
Predicted Primers |
PCR Primer
(F):5'- TGTCATCCTGGGCCTTAGAC -3'
(R):5'- GGCAACCTGCTGTATAATGTTTG -3'
Sequencing Primer
(F):5'- CGAGACATGTGGAATTTGCC -3'
(R):5'- AATGTTTGTTTACCCTAACCCAGG -3'
|
Posted On | 2019-06-07 |