Mutagenetix > Incidental Mutation

Incidental Mutation 'R0605:Prrc2c'

55620

Institutional Source

Beutler Lab

Gene Symbol

Prrc2c

Ensembl Gene

ENSMUSG00000040225

Gene Name

proline-rich coiled-coil 2C

Synonyms

9630039I18Rik, 1810043M20Rik, Bat2d, Bat2l2

MMRRC Submission

038794-MU

Accession Numbers

Essential gene?

Possibly non essential (E-score: 0.376) question?

Stock #

R0605 (G1)

Quality Score

225

Status

Validated

Chromosome

Chromosomal Location

162670725-162740556 bp(-) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

T to C at 162682426 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Threonine to Alanine at position 1017 (T1017A)

Ref Sequence

ENSEMBL: ENSMUSP00000138451 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000028016] [ENSMUST00000182149] [ENSMUST00000182393] [ENSMUST00000182593] [ENSMUST00000182660] [ENSMUST00000183223]

AlphaFold

no structure available at present

Predicted Effect

possibly damaging
Transcript: ENSMUST00000028016
AA Change: T2299A

PolyPhen 2 Score 0.528 (Sensitivity: 0.88; Specificity: 0.90)

SMART Domains

Protein: ENSMUSP00000028016
Gene: ENSMUSG00000040225
AA Change: T2299A

Domain	Start	End	E-Value	Type
Pfam:BAT2_N	1	164	7.7e-56	PFAM
internal_repeat_2	167	349	4.39e-5	PROSPERO
internal_repeat_1	336	391	2.14e-5	PROSPERO
low complexity region	407	414	N/A	INTRINSIC
SCOP:d1eq1a_	447	591	2e-5	SMART
low complexity region	649	669	N/A	INTRINSIC
low complexity region	733	745	N/A	INTRINSIC
coiled coil region	996	1026	N/A	INTRINSIC
low complexity region	1157	1186	N/A	INTRINSIC
low complexity region	1212	1222	N/A	INTRINSIC
internal_repeat_1	1240	1295	2.14e-5	PROSPERO
low complexity region	1308	1335	N/A	INTRINSIC
low complexity region	1388	1409	N/A	INTRINSIC
low complexity region	1715	1746	N/A	INTRINSIC
low complexity region	1765	1803	N/A	INTRINSIC
low complexity region	1815	1832	N/A	INTRINSIC
low complexity region	1844	1909	N/A	INTRINSIC
internal_repeat_2	1962	2148	4.39e-5	PROSPERO
low complexity region	2163	2177	N/A	INTRINSIC
low complexity region	2230	2252	N/A	INTRINSIC
low complexity region	2272	2286	N/A	INTRINSIC
low complexity region	2321	2338	N/A	INTRINSIC
low complexity region	2427	2438	N/A	INTRINSIC
low complexity region	2553	2576	N/A	INTRINSIC
low complexity region	2811	2828	N/A	INTRINSIC

Predicted Effect

possibly damaging
Transcript: ENSMUST00000182149
AA Change: T2301A

PolyPhen 2 Score 0.891 (Sensitivity: 0.82; Specificity: 0.94)

SMART Domains

Protein: ENSMUSP00000138548
Gene: ENSMUSG00000040225
AA Change: T2301A

Domain	Start	End	E-Value	Type
Pfam:BAT2_N	1	167	5.6e-73	PFAM
internal_repeat_1	336	391	1.49e-5	PROSPERO
low complexity region	407	414	N/A	INTRINSIC
SCOP:d1eq1a_	447	591	2e-5	SMART
low complexity region	649	669	N/A	INTRINSIC
low complexity region	733	745	N/A	INTRINSIC
internal_repeat_3	754	925	9.16e-5	PROSPERO
coiled coil region	996	1026	N/A	INTRINSIC
low complexity region	1157	1186	N/A	INTRINSIC
low complexity region	1212	1222	N/A	INTRINSIC
internal_repeat_1	1240	1295	1.49e-5	PROSPERO
low complexity region	1308	1335	N/A	INTRINSIC
low complexity region	1388	1409	N/A	INTRINSIC
low complexity region	1715	1746	N/A	INTRINSIC
low complexity region	1765	1803	N/A	INTRINSIC
low complexity region	1815	1832	N/A	INTRINSIC
low complexity region	1844	1909	N/A	INTRINSIC
internal_repeat_2	1962	2148	3.08e-5	PROSPERO
internal_repeat_3	1983	2153	9.16e-5	PROSPERO
low complexity region	2163	2177	N/A	INTRINSIC
low complexity region	2230	2252	N/A	INTRINSIC
low complexity region	2272	2286	N/A	INTRINSIC
low complexity region	2321	2338	N/A	INTRINSIC
low complexity region	2427	2438	N/A	INTRINSIC
low complexity region	2553	2576	N/A	INTRINSIC

Predicted Effect

probably damaging
Transcript: ENSMUST00000182393
AA Change: T1017A

PolyPhen 2 Score 0.997 (Sensitivity: 0.41; Specificity: 0.98)

SMART Domains

Protein: ENSMUSP00000138451
Gene: ENSMUSG00000040225
AA Change: T1017A

Domain	Start	End	E-Value	Type
low complexity region	24	51	N/A	INTRINSIC
low complexity region	104	125	N/A	INTRINSIC
low complexity region	431	462	N/A	INTRINSIC
low complexity region	481	519	N/A	INTRINSIC
low complexity region	531	548	N/A	INTRINSIC
low complexity region	560	625	N/A	INTRINSIC
low complexity region	879	893	N/A	INTRINSIC
low complexity region	946	968	N/A	INTRINSIC
low complexity region	988	1002	N/A	INTRINSIC
low complexity region	1037	1054	N/A	INTRINSIC
low complexity region	1143	1154	N/A	INTRINSIC
low complexity region	1274	1297	N/A	INTRINSIC

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000182535

Predicted Effect

possibly damaging
Transcript: ENSMUST00000182593
AA Change: T2299A

PolyPhen 2 Score 0.891 (Sensitivity: 0.82; Specificity: 0.94)

SMART Domains

Protein: ENSMUSP00000138674
Gene: ENSMUSG00000040225
AA Change: T2299A

Domain	Start	End	E-Value	Type
Pfam:BAT2_N	1	165	4.1e-70	PFAM
internal_repeat_1	334	389	9.57e-6	PROSPERO
low complexity region	405	412	N/A	INTRINSIC
SCOP:d1eq1a_	445	589	3e-5	SMART
low complexity region	647	667	N/A	INTRINSIC
low complexity region	731	743	N/A	INTRINSIC
internal_repeat_3	752	923	6.11e-5	PROSPERO
coiled coil region	994	1024	N/A	INTRINSIC
low complexity region	1155	1184	N/A	INTRINSIC
low complexity region	1210	1220	N/A	INTRINSIC
internal_repeat_1	1238	1293	9.57e-6	PROSPERO
low complexity region	1306	1333	N/A	INTRINSIC
low complexity region	1386	1407	N/A	INTRINSIC
low complexity region	1713	1744	N/A	INTRINSIC
low complexity region	1763	1801	N/A	INTRINSIC
low complexity region	1813	1830	N/A	INTRINSIC
low complexity region	1842	1907	N/A	INTRINSIC
internal_repeat_2	1960	2146	2.01e-5	PROSPERO
internal_repeat_3	1981	2151	6.11e-5	PROSPERO
low complexity region	2161	2175	N/A	INTRINSIC
low complexity region	2228	2250	N/A	INTRINSIC
low complexity region	2270	2284	N/A	INTRINSIC
low complexity region	2319	2336	N/A	INTRINSIC
low complexity region	2425	2436	N/A	INTRINSIC
low complexity region	2551	2574	N/A	INTRINSIC
low complexity region	2671	2682	N/A	INTRINSIC
low complexity region	2730	2747	N/A	INTRINSIC

Predicted Effect

possibly damaging
Transcript: ENSMUST00000182660
AA Change: T2301A

PolyPhen 2 Score 0.767 (Sensitivity: 0.85; Specificity: 0.92)

SMART Domains

Protein: ENSMUSP00000138433
Gene: ENSMUSG00000040225
AA Change: T2301A

Domain	Start	End	E-Value	Type
Pfam:BAT2_N	1	167	7e-73	PFAM
internal_repeat_1	336	391	2.14e-5	PROSPERO
low complexity region	407	414	N/A	INTRINSIC
SCOP:d1eq1a_	447	591	2e-5	SMART
low complexity region	649	669	N/A	INTRINSIC
low complexity region	733	745	N/A	INTRINSIC
coiled coil region	996	1026	N/A	INTRINSIC
low complexity region	1157	1186	N/A	INTRINSIC
low complexity region	1212	1222	N/A	INTRINSIC
internal_repeat_1	1240	1295	2.14e-5	PROSPERO
low complexity region	1308	1335	N/A	INTRINSIC
low complexity region	1388	1409	N/A	INTRINSIC
low complexity region	1715	1746	N/A	INTRINSIC
low complexity region	1765	1803	N/A	INTRINSIC
low complexity region	1815	1832	N/A	INTRINSIC
low complexity region	1844	1909	N/A	INTRINSIC
internal_repeat_2	1962	2148	4.39e-5	PROSPERO
low complexity region	2163	2177	N/A	INTRINSIC
low complexity region	2230	2252	N/A	INTRINSIC
low complexity region	2272	2286	N/A	INTRINSIC
low complexity region	2321	2338	N/A	INTRINSIC
low complexity region	2427	2438	N/A	INTRINSIC
low complexity region	2553	2576	N/A	INTRINSIC
low complexity region	2811	2828	N/A	INTRINSIC

Predicted Effect

probably damaging
Transcript: ENSMUST00000183223
AA Change: T810A

PolyPhen 2 Score 0.994 (Sensitivity: 0.69; Specificity: 0.97)

SMART Domains

Protein: ENSMUSP00000138698
Gene: ENSMUSG00000040225
AA Change: T810A

Domain	Start	End	E-Value	Type
low complexity region	289	320	N/A	INTRINSIC
low complexity region	339	377	N/A	INTRINSIC
low complexity region	389	406	N/A	INTRINSIC
low complexity region	418	483	N/A	INTRINSIC
low complexity region	739	761	N/A	INTRINSIC
low complexity region	781	795	N/A	INTRINSIC
low complexity region	830	847	N/A	INTRINSIC
low complexity region	936	947	N/A	INTRINSIC
low complexity region	1062	1085	N/A	INTRINSIC
low complexity region	1182	1193	N/A	INTRINSIC
low complexity region	1241	1258	N/A	INTRINSIC

Meta Mutation Damage Score

0.0678

Coding Region Coverage

1x: 99.4%
3x: 98.9%
10x: 97.6%
20x: 95.4%

Validation Efficiency

100% (85/85)

Allele List at MGI

Other mutations in this stock

Total: 84 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
4933406P04Rik	G	A	10: 20,311,227		probably benign	Het
Adam28	A	T	14: 68,606,600		probably benign	Het
Adamts3	A	G	5: 89,861,475	W110R	possibly damaging	Het
Add1	T	C	5: 34,614,224	V342A	possibly damaging	Het
Aff3	A	G	1: 38,209,987	S680P	probably damaging	Het
Ak9	T	C	10: 41,345,139	Y322H	probably damaging	Het
Als2	A	G	1: 59,168,414	L1528S	probably benign	Het
Ass1	A	T	2: 31,514,819	N371Y	probably damaging	Het
Atp6v1a	A	C	16: 44,111,496		probably null	Het
Bpi	T	C	2: 158,261,394	L103P	probably damaging	Het
Cd80	G	A	16: 38,482,694	V168I	probably benign	Het
Cfh	T	C	1: 140,102,358	S926G	probably damaging	Het
Chrd	A	T	16: 20,735,439	T304S	probably damaging	Het
Chsy3	A	G	18: 59,409,053	Y421C	probably damaging	Het
Cmbl	T	G	15: 31,585,309	V101G	probably damaging	Het
Colgalt2	T	A	1: 152,495,792		probably benign	Het
Coq4	C	T	2: 29,789,998	Q101*	probably null	Het
Cr2	T	C	1: 195,163,596		probably benign	Het
Cry1	T	C	10: 85,184,359	D38G	probably damaging	Het
Dmxl2	T	C	9: 54,419,945	D758G	probably benign	Het
Epsti1	C	T	14: 77,927,237		probably benign	Het
Fam24b	T	C	7: 131,327,186		probably benign	Het
Fem1c	G	A	18: 46,505,160	R592C	probably benign	Het
Foxred1	T	C	9: 35,204,882	Y490C	possibly damaging	Het
Gm14124	A	G	2: 150,268,603	I404M	unknown	Het
Gm9875	A	G	2: 13,557,888	K9R	unknown	Het
Grid2ip	T	C	5: 143,379,362	S322P	probably damaging	Het
Gucy1b2	A	G	14: 62,403,159		probably benign	Het
Hmcn1	A	T	1: 150,657,376		probably null	Het
Hpdl	C	T	4: 116,820,787	S159N	possibly damaging	Het
Hsd17b12	A	T	2: 94,033,642	M285K	probably benign	Het
Icam5	T	C	9: 21,032,197	I23T	probably benign	Het
Kat5	A	G	19: 5,608,336		probably benign	Het
Lama3	A	G	18: 12,506,949	N67S	probably benign	Het
Lamb2	T	C	9: 108,486,105		probably benign	Het
Lgals3bp	A	G	11: 118,393,394	F453S	probably damaging	Het
Lypd4	A	G	7: 24,865,375	Y113H	probably damaging	Het
Mdm1	C	T	10: 118,146,601	T47M	probably damaging	Het
Mei1	C	A	15: 82,070,150	T52K	probably benign	Het
Meiob	G	A	17: 24,818,262		probably benign	Het
Ndufaf6	A	G	4: 11,051,224	V292A	probably damaging	Het
Neb	T	A	2: 52,264,026	M2358L	possibly damaging	Het
Nlrp1b	A	G	11: 71,156,179	S1119P	possibly damaging	Het
Nsmaf	A	G	4: 6,418,470		probably null	Het
Ogfod1	T	C	8: 94,047,267		probably benign	Het
Olfr1097	T	C	2: 86,890,419	Y252C	possibly damaging	Het
Olfr1410	G	T	1: 92,607,896	V20L	probably benign	Het
Olfr291	T	C	7: 84,857,137	I256T	probably damaging	Het
Osbpl1a	T	A	18: 12,882,279		probably null	Het
Otud7b	T	A	3: 96,144,959		probably benign	Het
P3h3	T	A	6: 124,856,035	H185L	probably damaging	Het
P4htm	G	A	9: 108,583,724	A183V	probably null	Het
Peak1	C	T	9: 56,227,098		probably benign	Het
Phf20l1	A	G	15: 66,595,122	K88R	probably damaging	Het
Phlpp2	A	G	8: 109,933,211	N721S	probably benign	Het
Plagl2	T	C	2: 153,235,944	K39R	probably benign	Het
Plppr1	A	T	4: 49,323,466	N252I	probably damaging	Het
Pom121l2	C	T	13: 21,982,036	A159V	probably damaging	Het
Prom2	C	A	2: 127,539,995		probably null	Het
Rimbp3	G	T	16: 17,211,699	A996S	probably damaging	Het
Rnf213	A	G	11: 119,431,717	T1387A	probably benign	Het
Scaper	A	T	9: 55,815,518		probably benign	Het
Scara5	A	G	14: 65,759,648	E403G	possibly damaging	Het
Scrib	T	C	15: 76,067,553	I94V	possibly damaging	Het
Shank3	T	C	15: 89,524,147	F67L	possibly damaging	Het
Shprh	T	C	10: 11,207,112	F1562L	probably damaging	Het
Src	C	T	2: 157,469,921	T529M	probably damaging	Het
Sycp2l	T	A	13: 41,143,466	M341K	probably benign	Het
Syde1	T	C	10: 78,589,095		probably benign	Het
Tarsl2	A	T	7: 65,678,071	R509S	probably damaging	Het
Tle6	T	A	10: 81,594,346	H324L	probably damaging	Het
Tnfaip8	ACTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTC	ACTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTC	18: 50,046,845		probably benign	Het
Tnfrsf14	T	A	4: 154,925,380	K115*	probably null	Het
Trappc10	T	C	10: 78,201,497	N824S	possibly damaging	Het
Tsc1	C	T	2: 28,671,778	S309F	probably damaging	Het
Ttc21a	A	G	9: 119,961,842	I885V	possibly damaging	Het
Ttn	C	T	2: 76,740,453	A26699T	probably damaging	Het
Ttn	T	C	2: 76,948,371	Y1262C	unknown	Het
Usp49	T	C	17: 47,674,926		probably null	Het
Vmn1r226	A	T	17: 20,687,871	T122S	probably benign	Het
Vps8	A	T	16: 21,559,337	T1033S	probably benign	Het
Vwf	C	A	6: 125,685,837	T2728K	probably benign	Het
Wdr5b	T	C	16: 36,041,996	S162P	probably benign	Het
Xrn1	C	T	9: 96,026,877	Q1235*	probably null	Het

Other mutations in Prrc2c

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00425:Prrc2c	APN	1	162720613	splice site	probably null
IGL00577:Prrc2c	APN	1	162698116	missense	unknown
IGL00580:Prrc2c	APN	1	162698116	missense	unknown
IGL01295:Prrc2c	APN	1	162682492	missense	probably damaging	1.00
IGL01554:Prrc2c	APN	1	162710786	missense	probably damaging	0.99
IGL01684:Prrc2c	APN	1	162706462	unclassified	probably benign
IGL01745:Prrc2c	APN	1	162724728	missense	probably damaging	1.00
IGL01770:Prrc2c	APN	1	162704499	missense	probably benign	0.23
IGL01905:Prrc2c	APN	1	162705329	unclassified	probably benign
IGL02304:Prrc2c	APN	1	162684136	missense	probably benign	0.05
IGL02389:Prrc2c	APN	1	162692870	missense	probably damaging	1.00
IGL02540:Prrc2c	APN	1	162723137	missense	probably damaging	1.00
IGL02681:Prrc2c	APN	1	162705612	unclassified	probably benign
IGL02686:Prrc2c	APN	1	162707947	unclassified	probably benign
IGL02795:Prrc2c	APN	1	162714299	missense	probably benign
IGL02894:Prrc2c	APN	1	162678057	missense	probably damaging	1.00
IGL02957:Prrc2c	APN	1	162706535	unclassified	probably benign
IGL02981:Prrc2c	APN	1	162705179	unclassified	probably benign
IGL03070:Prrc2c	APN	1	162677409	missense	probably damaging	1.00
IGL03096:Prrc2c	APN	1	162702359	missense	unknown
R0058:Prrc2c	UTSW	1	162698884	missense	unknown
R0058:Prrc2c	UTSW	1	162698884	missense	unknown
R0135:Prrc2c	UTSW	1	162715483	splice site	probably benign
R0279:Prrc2c	UTSW	1	162715464	missense	probably damaging	1.00
R0363:Prrc2c	UTSW	1	162697811	missense	unknown
R0436:Prrc2c	UTSW	1	162705314	unclassified	probably benign
R0696:Prrc2c	UTSW	1	162708852	critical splice donor site	probably null
R0981:Prrc2c	UTSW	1	162705981	unclassified	probably benign
R1693:Prrc2c	UTSW	1	162718713	missense	probably damaging	0.98
R1714:Prrc2c	UTSW	1	162677376	missense	probably damaging	1.00
R1791:Prrc2c	UTSW	1	162704982	unclassified	probably benign
R1794:Prrc2c	UTSW	1	162705959	unclassified	probably benign
R1998:Prrc2c	UTSW	1	162704918	unclassified	probably benign
R2040:Prrc2c	UTSW	1	162697557	missense	probably damaging	1.00
R2168:Prrc2c	UTSW	1	162710334	unclassified	probably benign
R2246:Prrc2c	UTSW	1	162707791	unclassified	probably benign
R2830:Prrc2c	UTSW	1	162708916	unclassified	probably benign
R2926:Prrc2c	UTSW	1	162706127	unclassified	probably benign
R3703:Prrc2c	UTSW	1	162710691	missense	probably damaging	1.00
R3745:Prrc2c	UTSW	1	162698185	missense	unknown
R3760:Prrc2c	UTSW	1	162692851	missense	probably damaging	1.00
R3784:Prrc2c	UTSW	1	162709669	unclassified	probably benign
R3959:Prrc2c	UTSW	1	162708892	unclassified	probably benign
R4255:Prrc2c	UTSW	1	162706326	unclassified	probably benign
R4276:Prrc2c	UTSW	1	162673591	missense	probably damaging	1.00
R4421:Prrc2c	UTSW	1	162709061	unclassified	probably benign
R4593:Prrc2c	UTSW	1	162697532	missense	probably damaging	1.00
R4651:Prrc2c	UTSW	1	162723274	missense	probably damaging	1.00
R4652:Prrc2c	UTSW	1	162723274	missense	probably damaging	1.00
R4660:Prrc2c	UTSW	1	162680895	missense	probably damaging	1.00
R4677:Prrc2c	UTSW	1	162705179	unclassified	probably benign
R4688:Prrc2c	UTSW	1	162697687	missense	unknown
R4753:Prrc2c	UTSW	1	162691230	missense	probably damaging	1.00
R4790:Prrc2c	UTSW	1	162710481	missense	unknown
R4981:Prrc2c	UTSW	1	162692547	missense	probably damaging	1.00
R4995:Prrc2c	UTSW	1	162705310	unclassified	probably benign
R5119:Prrc2c	UTSW	1	162705440	unclassified	probably benign
R5127:Prrc2c	UTSW	1	162697846	missense	unknown
R5291:Prrc2c	UTSW	1	162705582	unclassified	probably benign
R5474:Prrc2c	UTSW	1	162709644	unclassified	probably benign
R5543:Prrc2c	UTSW	1	162673511	missense	probably damaging	0.99
R5579:Prrc2c	UTSW	1	162680758	critical splice donor site	probably null
R5594:Prrc2c	UTSW	1	162699031	missense	unknown
R5620:Prrc2c	UTSW	1	162673529	missense	probably damaging	1.00
R5994:Prrc2c	UTSW	1	162674156	splice site	probably null
R6142:Prrc2c	UTSW	1	162710387	missense	unknown
R6199:Prrc2c	UTSW	1	162682516	missense	probably damaging	1.00
R6277:Prrc2c	UTSW	1	162714314	missense	probably benign
R6504:Prrc2c	UTSW	1	162697795	missense	unknown
R6671:Prrc2c	UTSW	1	162697585	missense	probably damaging	1.00
R6785:Prrc2c	UTSW	1	162709101	unclassified	probably benign
R6799:Prrc2c	UTSW	1	162709061	unclassified	probably benign
R6801:Prrc2c	UTSW	1	162709061	unclassified	probably benign
R6850:Prrc2c	UTSW	1	162709061	unclassified	probably benign
R6851:Prrc2c	UTSW	1	162709061	unclassified	probably benign
R6856:Prrc2c	UTSW	1	162682371	missense	probably damaging	1.00
R6869:Prrc2c	UTSW	1	162709061	unclassified	probably benign
R6882:Prrc2c	UTSW	1	162709061	unclassified	probably benign
R6884:Prrc2c	UTSW	1	162709061	unclassified	probably benign
R6897:Prrc2c	UTSW	1	162705506	unclassified	probably benign
R6934:Prrc2c	UTSW	1	162720505	missense	probably benign	0.10
R6976:Prrc2c	UTSW	1	162692844	missense	probably damaging	1.00
R7132:Prrc2c	UTSW	1	162681281	missense	possibly damaging	0.77
R7165:Prrc2c	UTSW	1	162673517	missense	possibly damaging	0.94
R7282:Prrc2c	UTSW	1	162679974	missense	possibly damaging	0.59
R7467:Prrc2c	UTSW	1	162677363	missense	possibly damaging	0.84
R7915:Prrc2c	UTSW	1	162692408	missense	probably benign	0.39
R8068:Prrc2c	UTSW	1	162709061	unclassified	probably benign
R8529:Prrc2c	UTSW	1	162709094	unclassified	probably benign
R8734:Prrc2c	UTSW	1	162679512	missense	possibly damaging	0.92
R8735:Prrc2c	UTSW	1	162709558	missense	unknown
R8813:Prrc2c	UTSW	1	162705243	missense	unknown
R8946:Prrc2c	UTSW	1	162708909	unclassified	probably benign
R8975:Prrc2c	UTSW	1	162706061	missense	unknown
R9035:Prrc2c	UTSW	1	162675726	missense	possibly damaging	0.96
R9185:Prrc2c	UTSW	1	162704643	missense	unknown
R9261:Prrc2c	UTSW	1	162678053	missense	possibly damaging	0.48
R9287:Prrc2c	UTSW	1	162714274	missense	probably benign	0.34
R9289:Prrc2c	UTSW	1	162679561	missense	probably benign	0.33
R9466:Prrc2c	UTSW	1	162675689	missense	possibly damaging	0.53
R9523:Prrc2c	UTSW	1	162697729	missense	unknown
R9542:Prrc2c	UTSW	1	162680790	missense	possibly damaging	0.88
R9629:Prrc2c	UTSW	1	162692390	missense	possibly damaging	0.95
R9744:Prrc2c	UTSW	1	162678164	missense	possibly damaging	0.96
R9748:Prrc2c	UTSW	1	162707866	missense	unknown
X0020:Prrc2c	UTSW	1	162707847	unclassified	probably benign
X0039:Prrc2c	UTSW	1	162704793	frame shift	probably null

Predicted Primers

PCR Primer
(F):5'- GTCATGGATGGAAGGGACTCAAACC -3'
(R):5'- CCAGTGGCCTATTTTCAGGTCAAGC -3'

Sequencing Primer
(F):5'- TCTAAGCAGCAAGAGTCACG -3'
(R):5'- GTACCTCCTGAGTATGGAGACTAC -3'

Posted On

2013-07-11