Incidental Mutation 'R0605:Cr2'
| ID |
55621 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Cr2
|
| Ensembl Gene |
ENSMUSG00000026616 |
| Gene Name |
complement receptor 2 |
| Synonyms |
C3DR, CD21, Cr-1, Cr1, CD35, Cr-2 |
| MMRRC Submission |
038794-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.140)
|
| Stock # |
R0605 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
1 |
| Chromosomal Location |
195136811-195176716 bp(-) (GRCm38) |
| Type of Mutation |
splice site |
| DNA Base Change (assembly) |
T to C
at 195163596 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000147804
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000043104]
[ENSMUST00000082321]
[ENSMUST00000193356]
[ENSMUST00000193801]
[ENSMUST00000195120]
[ENSMUST00000210219]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000043104
|
| SMART Domains |
Protein: ENSMUSP00000044261
Gene: ENSMUSG00000026616
| Domain | Start | End | E-Value | Type |
|---|
|
CCP
|
2 |
58 |
5.04e-7 |
SMART |
|
CCP
|
63 |
120 |
3.58e-12 |
SMART |
|
CCP
|
125 |
191 |
1.2e-13 |
SMART |
|
CCP
|
197 |
252 |
2.73e-17 |
SMART |
|
CCP
|
256 |
311 |
1.01e-15 |
SMART |
|
Blast:CCP
|
316 |
347 |
2e-13 |
BLAST |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000082321
|
| SMART Domains |
Protein: ENSMUSP00000080938
Gene: ENSMUSG00000026616
| Domain | Start | End | E-Value | Type |
|---|
|
CCP
|
23 |
82 |
1.01e-11 |
SMART |
|
CCP
|
91 |
147 |
9.1e-14 |
SMART |
|
CCP
|
155 |
211 |
1.9e-16 |
SMART |
|
CCP
|
216 |
272 |
1.6e-9 |
SMART |
|
CCP
|
277 |
343 |
1.01e-11 |
SMART |
|
CCP
|
352 |
407 |
1.2e-13 |
SMART |
|
CCP
|
411 |
467 |
2.34e-16 |
SMART |
|
CCP
|
472 |
523 |
1.24e0 |
SMART |
|
CCP
|
528 |
594 |
4.48e-13 |
SMART |
|
CCP
|
603 |
658 |
1.95e-13 |
SMART |
|
CCP
|
718 |
778 |
1.75e-15 |
SMART |
|
CCP
|
787 |
842 |
2.06e-12 |
SMART |
|
CCP
|
850 |
906 |
7.92e-14 |
SMART |
|
CCP
|
911 |
967 |
1.29e-13 |
SMART |
|
transmembrane domain
|
975 |
997 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000193356
|
| SMART Domains |
Protein: ENSMUSP00000141706
Gene: ENSMUSG00000026616
| Domain | Start | End | E-Value | Type |
|---|
|
CCP
|
1 |
46 |
1.2e-1 |
SMART |
|
CCP
|
55 |
110 |
5.9e-16 |
SMART |
|
CCP
|
114 |
170 |
1.1e-18 |
SMART |
|
CCP
|
175 |
226 |
6.1e-3 |
SMART |
|
CCP
|
231 |
297 |
2.2e-15 |
SMART |
|
CCP
|
306 |
361 |
9.4e-16 |
SMART |
|
CCP
|
421 |
481 |
8.3e-18 |
SMART |
|
CCP
|
490 |
545 |
1e-14 |
SMART |
|
CCP
|
553 |
609 |
4e-16 |
SMART |
|
CCP
|
614 |
670 |
6.2e-16 |
SMART |
|
transmembrane domain
|
678 |
700 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000193801
|
| SMART Domains |
Protein: ENSMUSP00000141276
Gene: ENSMUSG00000026616
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
20 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000194149
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000195120
|
| SMART Domains |
Protein: ENSMUSP00000141538
Gene: ENSMUSG00000026616
| Domain | Start | End | E-Value | Type |
|---|
|
CCP
|
23 |
82 |
4.9e-14 |
SMART |
|
CCP
|
91 |
147 |
4.5e-16 |
SMART |
|
CCP
|
155 |
211 |
9.1e-19 |
SMART |
|
CCP
|
216 |
272 |
8e-12 |
SMART |
|
CCP
|
277 |
343 |
5e-14 |
SMART |
|
CCP
|
352 |
407 |
5.9e-16 |
SMART |
|
CCP
|
411 |
467 |
1.1e-18 |
SMART |
|
CCP
|
472 |
523 |
6.1e-3 |
SMART |
|
CCP
|
528 |
594 |
2.2e-15 |
SMART |
|
CCP
|
603 |
658 |
9.4e-16 |
SMART |
|
CCP
|
718 |
778 |
8.3e-18 |
SMART |
|
CCP
|
787 |
842 |
1e-14 |
SMART |
|
CCP
|
850 |
906 |
4e-16 |
SMART |
|
CCP
|
911 |
967 |
6.2e-16 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000195347
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000210219
|
| Coding Region Coverage |
- 1x: 99.4%
- 3x: 98.9%
- 10x: 97.6%
- 20x: 95.4%
|
| Validation Efficiency |
100% (85/85) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a membrane protein, which functions as a receptor for Epstein-Barr virus (EBV) binding on B and T lymphocytes. Genetic variations in this gene are associated with susceptibility to systemic lupus erythematosus type 9 (SLEB9). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009]
PHENOTYPE: Homozygotes for targeted null mutations exhibit impaired humoral immune responses to T cell-dependent antigens, with limited affinity maturation, and reduced memory B cell and germinal center formation. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 84 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4933406P04Rik |
G |
A |
10: 20,311,227 (GRCm38) |
|
probably benign |
Het |
| Adam28 |
A |
T |
14: 68,606,600 (GRCm38) |
|
probably benign |
Het |
| Adamts3 |
A |
G |
5: 89,861,475 (GRCm38) |
W110R |
possibly damaging |
Het |
| Add1 |
T |
C |
5: 34,614,224 (GRCm38) |
V342A |
possibly damaging |
Het |
| Aff3 |
A |
G |
1: 38,209,987 (GRCm38) |
S680P |
probably damaging |
Het |
| Ak9 |
T |
C |
10: 41,345,139 (GRCm38) |
Y322H |
probably damaging |
Het |
| Als2 |
A |
G |
1: 59,168,414 (GRCm38) |
L1528S |
probably benign |
Het |
| Ass1 |
A |
T |
2: 31,514,819 (GRCm38) |
N371Y |
probably damaging |
Het |
| Atp6v1a |
A |
C |
16: 44,111,496 (GRCm38) |
|
probably null |
Het |
| Bpi |
T |
C |
2: 158,261,394 (GRCm38) |
L103P |
probably damaging |
Het |
| Cd80 |
G |
A |
16: 38,482,694 (GRCm38) |
V168I |
probably benign |
Het |
| Cfh |
T |
C |
1: 140,102,358 (GRCm38) |
S926G |
probably damaging |
Het |
| Chrd |
A |
T |
16: 20,735,439 (GRCm38) |
T304S |
probably damaging |
Het |
| Chsy3 |
A |
G |
18: 59,409,053 (GRCm38) |
Y421C |
probably damaging |
Het |
| Cmbl |
T |
G |
15: 31,585,309 (GRCm38) |
V101G |
probably damaging |
Het |
| Colgalt2 |
T |
A |
1: 152,495,792 (GRCm38) |
|
probably benign |
Het |
| Coq4 |
C |
T |
2: 29,789,998 (GRCm38) |
Q101* |
probably null |
Het |
| Cry1 |
T |
C |
10: 85,184,359 (GRCm38) |
D38G |
probably damaging |
Het |
| Dmxl2 |
T |
C |
9: 54,419,945 (GRCm38) |
D758G |
probably benign |
Het |
| Epsti1 |
C |
T |
14: 77,927,237 (GRCm38) |
|
probably benign |
Het |
| Fam24b |
T |
C |
7: 131,327,186 (GRCm38) |
|
probably benign |
Het |
| Fem1c |
G |
A |
18: 46,505,160 (GRCm38) |
R592C |
probably benign |
Het |
| Foxred1 |
T |
C |
9: 35,204,882 (GRCm38) |
Y490C |
possibly damaging |
Het |
| Gm14124 |
A |
G |
2: 150,268,603 (GRCm38) |
I404M |
unknown |
Het |
| Gm9875 |
A |
G |
2: 13,557,888 (GRCm38) |
K9R |
unknown |
Het |
| Grid2ip |
T |
C |
5: 143,379,362 (GRCm38) |
S322P |
probably damaging |
Het |
| Gucy1b2 |
A |
G |
14: 62,403,159 (GRCm38) |
|
probably benign |
Het |
| Hmcn1 |
A |
T |
1: 150,657,376 (GRCm38) |
|
probably null |
Het |
| Hpdl |
C |
T |
4: 116,820,787 (GRCm38) |
S159N |
possibly damaging |
Het |
| Hsd17b12 |
A |
T |
2: 94,033,642 (GRCm38) |
M285K |
probably benign |
Het |
| Icam5 |
T |
C |
9: 21,032,197 (GRCm38) |
I23T |
probably benign |
Het |
| Kat5 |
A |
G |
19: 5,608,336 (GRCm38) |
|
probably benign |
Het |
| Lama3 |
A |
G |
18: 12,506,949 (GRCm38) |
N67S |
probably benign |
Het |
| Lamb2 |
T |
C |
9: 108,486,105 (GRCm38) |
|
probably benign |
Het |
| Lgals3bp |
A |
G |
11: 118,393,394 (GRCm38) |
F453S |
probably damaging |
Het |
| Lypd4 |
A |
G |
7: 24,865,375 (GRCm38) |
Y113H |
probably damaging |
Het |
| Mdm1 |
C |
T |
10: 118,146,601 (GRCm38) |
T47M |
probably damaging |
Het |
| Mei1 |
C |
A |
15: 82,070,150 (GRCm38) |
T52K |
probably benign |
Het |
| Meiob |
G |
A |
17: 24,818,262 (GRCm38) |
|
probably benign |
Het |
| Ndufaf6 |
A |
G |
4: 11,051,224 (GRCm38) |
V292A |
probably damaging |
Het |
| Neb |
T |
A |
2: 52,264,026 (GRCm38) |
M2358L |
possibly damaging |
Het |
| Nlrp1b |
A |
G |
11: 71,156,179 (GRCm38) |
S1119P |
possibly damaging |
Het |
| Nsmaf |
A |
G |
4: 6,418,470 (GRCm38) |
|
probably null |
Het |
| Ogfod1 |
T |
C |
8: 94,047,267 (GRCm38) |
|
probably benign |
Het |
| Olfr1097 |
T |
C |
2: 86,890,419 (GRCm38) |
Y252C |
possibly damaging |
Het |
| Olfr1410 |
G |
T |
1: 92,607,896 (GRCm38) |
V20L |
probably benign |
Het |
| Olfr291 |
T |
C |
7: 84,857,137 (GRCm38) |
I256T |
probably damaging |
Het |
| Osbpl1a |
T |
A |
18: 12,882,279 (GRCm38) |
|
probably null |
Het |
| Otud7b |
T |
A |
3: 96,144,959 (GRCm38) |
|
probably benign |
Het |
| P3h3 |
T |
A |
6: 124,856,035 (GRCm38) |
H185L |
probably damaging |
Het |
| P4htm |
G |
A |
9: 108,583,724 (GRCm38) |
A183V |
probably null |
Het |
| Peak1 |
C |
T |
9: 56,227,098 (GRCm38) |
|
probably benign |
Het |
| Phf20l1 |
A |
G |
15: 66,595,122 (GRCm38) |
K88R |
probably damaging |
Het |
| Phlpp2 |
A |
G |
8: 109,933,211 (GRCm38) |
N721S |
probably benign |
Het |
| Plagl2 |
T |
C |
2: 153,235,944 (GRCm38) |
K39R |
probably benign |
Het |
| Plppr1 |
A |
T |
4: 49,323,466 (GRCm38) |
N252I |
probably damaging |
Het |
| Pom121l2 |
C |
T |
13: 21,982,036 (GRCm38) |
A159V |
probably damaging |
Het |
| Prom2 |
C |
A |
2: 127,539,995 (GRCm38) |
|
probably null |
Het |
| Prrc2c |
T |
C |
1: 162,682,426 (GRCm38) |
T1017A |
probably damaging |
Het |
| Rimbp3 |
G |
T |
16: 17,211,699 (GRCm38) |
A996S |
probably damaging |
Het |
| Rnf213 |
A |
G |
11: 119,431,717 (GRCm38) |
T1387A |
probably benign |
Het |
| Scaper |
A |
T |
9: 55,815,518 (GRCm38) |
|
probably benign |
Het |
| Scara5 |
A |
G |
14: 65,759,648 (GRCm38) |
E403G |
possibly damaging |
Het |
| Scrib |
T |
C |
15: 76,067,553 (GRCm38) |
I94V |
possibly damaging |
Het |
| Shank3 |
T |
C |
15: 89,524,147 (GRCm38) |
F67L |
possibly damaging |
Het |
| Shprh |
T |
C |
10: 11,207,112 (GRCm38) |
F1562L |
probably damaging |
Het |
| Src |
C |
T |
2: 157,469,921 (GRCm38) |
T529M |
probably damaging |
Het |
| Sycp2l |
T |
A |
13: 41,143,466 (GRCm38) |
M341K |
probably benign |
Het |
| Syde1 |
T |
C |
10: 78,589,095 (GRCm38) |
|
probably benign |
Het |
| Tarsl2 |
A |
T |
7: 65,678,071 (GRCm38) |
R509S |
probably damaging |
Het |
| Tle6 |
T |
A |
10: 81,594,346 (GRCm38) |
H324L |
probably damaging |
Het |
| Tnfaip8 |
ACTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTC |
ACTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTC |
18: 50,046,845 (GRCm38) |
|
probably benign |
Het |
| Tnfrsf14 |
T |
A |
4: 154,925,380 (GRCm38) |
K115* |
probably null |
Het |
| Trappc10 |
T |
C |
10: 78,201,497 (GRCm38) |
N824S |
possibly damaging |
Het |
| Tsc1 |
C |
T |
2: 28,671,778 (GRCm38) |
S309F |
probably damaging |
Het |
| Ttc21a |
A |
G |
9: 119,961,842 (GRCm38) |
I885V |
possibly damaging |
Het |
| Ttn |
T |
C |
2: 76,948,371 (GRCm38) |
Y1262C |
unknown |
Het |
| Ttn |
C |
T |
2: 76,740,453 (GRCm38) |
A26699T |
probably damaging |
Het |
| Usp49 |
T |
C |
17: 47,674,926 (GRCm38) |
|
probably null |
Het |
| Vmn1r226 |
A |
T |
17: 20,687,871 (GRCm38) |
T122S |
probably benign |
Het |
| Vps8 |
A |
T |
16: 21,559,337 (GRCm38) |
T1033S |
probably benign |
Het |
| Vwf |
C |
A |
6: 125,685,837 (GRCm38) |
T2728K |
probably benign |
Het |
| Wdr5b |
T |
C |
16: 36,041,996 (GRCm38) |
S162P |
probably benign |
Het |
| Xrn1 |
C |
T |
9: 96,026,877 (GRCm38) |
Q1235* |
probably null |
Het |
|
| Other mutations in Cr2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00587:Cr2
|
APN |
1 |
195,154,251 (GRCm38) |
missense |
possibly damaging |
0.76 |
|
IGL01326:Cr2
|
APN |
1 |
195,141,221 (GRCm38) |
missense |
probably null |
1.00 |
|
IGL01358:Cr2
|
APN |
1 |
195,159,820 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01410:Cr2
|
APN |
1 |
195,163,234 (GRCm38) |
missense |
possibly damaging |
0.49 |
|
IGL01468:Cr2
|
APN |
1 |
195,168,535 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01608:Cr2
|
APN |
1 |
195,155,220 (GRCm38) |
missense |
possibly damaging |
0.50 |
|
IGL01810:Cr2
|
APN |
1 |
195,159,595 (GRCm38) |
missense |
possibly damaging |
0.49 |
|
IGL01843:Cr2
|
APN |
1 |
195,150,914 (GRCm38) |
splice site |
probably benign |
|
|
IGL02332:Cr2
|
APN |
1 |
195,160,322 (GRCm38) |
missense |
probably benign |
0.19 |
|
IGL02934:Cr2
|
APN |
1 |
195,154,325 (GRCm38) |
splice site |
probably benign |
|
|
IGL02938:Cr2
|
APN |
1 |
195,166,388 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL03149:Cr2
|
APN |
1 |
195,166,366 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL03327:Cr2
|
APN |
1 |
195,169,759 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL03346:Cr2
|
APN |
1 |
195,169,759 (GRCm38) |
missense |
probably damaging |
1.00 |
|
Pillar
|
UTSW |
1 |
195,155,888 (GRCm38) |
nonsense |
probably null |
|
|
PIT4354001:Cr2
|
UTSW |
1 |
195,166,309 (GRCm38) |
missense |
probably damaging |
1.00 |
|
PIT4418001:Cr2
|
UTSW |
1 |
195,157,452 (GRCm38) |
missense |
probably benign |
0.08 |
|
R0128:Cr2
|
UTSW |
1 |
195,166,231 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R0130:Cr2
|
UTSW |
1 |
195,166,231 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R0380:Cr2
|
UTSW |
1 |
195,157,407 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0538:Cr2
|
UTSW |
1 |
195,160,359 (GRCm38) |
splice site |
probably benign |
|
|
R0626:Cr2
|
UTSW |
1 |
195,171,111 (GRCm38) |
missense |
possibly damaging |
0.95 |
|
R1135:Cr2
|
UTSW |
1 |
195,157,190 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1396:Cr2
|
UTSW |
1 |
195,169,253 (GRCm38) |
splice site |
probably null |
|
|
R1422:Cr2
|
UTSW |
1 |
195,171,125 (GRCm38) |
missense |
probably benign |
0.01 |
|
R1467:Cr2
|
UTSW |
1 |
195,157,509 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1467:Cr2
|
UTSW |
1 |
195,157,509 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1511:Cr2
|
UTSW |
1 |
195,155,272 (GRCm38) |
missense |
possibly damaging |
0.92 |
|
R1572:Cr2
|
UTSW |
1 |
195,163,314 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1714:Cr2
|
UTSW |
1 |
195,151,686 (GRCm38) |
missense |
possibly damaging |
0.46 |
|
R1748:Cr2
|
UTSW |
1 |
195,155,905 (GRCm38) |
nonsense |
probably null |
|
|
R1761:Cr2
|
UTSW |
1 |
195,155,123 (GRCm38) |
critical splice donor site |
probably null |
|
|
R1824:Cr2
|
UTSW |
1 |
195,157,316 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1893:Cr2
|
UTSW |
1 |
195,155,187 (GRCm38) |
missense |
probably benign |
0.03 |
|
R1990:Cr2
|
UTSW |
1 |
195,154,150 (GRCm38) |
missense |
possibly damaging |
0.63 |
|
R1991:Cr2
|
UTSW |
1 |
195,154,150 (GRCm38) |
missense |
possibly damaging |
0.63 |
|
R1992:Cr2
|
UTSW |
1 |
195,154,150 (GRCm38) |
missense |
possibly damaging |
0.63 |
|
R2191:Cr2
|
UTSW |
1 |
195,163,381 (GRCm38) |
missense |
possibly damaging |
0.94 |
|
R2276:Cr2
|
UTSW |
1 |
195,157,368 (GRCm38) |
missense |
possibly damaging |
0.94 |
|
R2277:Cr2
|
UTSW |
1 |
195,157,368 (GRCm38) |
missense |
possibly damaging |
0.94 |
|
R3548:Cr2
|
UTSW |
1 |
195,155,888 (GRCm38) |
nonsense |
probably null |
|
|
R3743:Cr2
|
UTSW |
1 |
195,149,966 (GRCm38) |
splice site |
probably benign |
|
|
R3941:Cr2
|
UTSW |
1 |
195,165,814 (GRCm38) |
missense |
probably damaging |
0.97 |
|
R3963:Cr2
|
UTSW |
1 |
195,159,739 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4211:Cr2
|
UTSW |
1 |
195,156,328 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R4484:Cr2
|
UTSW |
1 |
195,154,174 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4546:Cr2
|
UTSW |
1 |
195,171,041 (GRCm38) |
missense |
possibly damaging |
0.94 |
|
R4791:Cr2
|
UTSW |
1 |
195,155,935 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4801:Cr2
|
UTSW |
1 |
195,163,311 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4802:Cr2
|
UTSW |
1 |
195,163,311 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4874:Cr2
|
UTSW |
1 |
195,176,570 (GRCm38) |
missense |
possibly damaging |
0.82 |
|
R4885:Cr2
|
UTSW |
1 |
195,158,731 (GRCm38) |
missense |
possibly damaging |
0.92 |
|
R4889:Cr2
|
UTSW |
1 |
195,176,585 (GRCm38) |
missense |
possibly damaging |
0.70 |
|
R5154:Cr2
|
UTSW |
1 |
195,159,446 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5574:Cr2
|
UTSW |
1 |
195,141,236 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5594:Cr2
|
UTSW |
1 |
195,157,190 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5645:Cr2
|
UTSW |
1 |
195,154,273 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5700:Cr2
|
UTSW |
1 |
195,159,757 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R5929:Cr2
|
UTSW |
1 |
195,171,111 (GRCm38) |
missense |
possibly damaging |
0.91 |
|
R6237:Cr2
|
UTSW |
1 |
195,157,502 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6299:Cr2
|
UTSW |
1 |
195,168,646 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6368:Cr2
|
UTSW |
1 |
195,168,472 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6406:Cr2
|
UTSW |
1 |
195,169,771 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6618:Cr2
|
UTSW |
1 |
195,157,379 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R6684:Cr2
|
UTSW |
1 |
195,171,021 (GRCm38) |
nonsense |
probably null |
|
|
R6720:Cr2
|
UTSW |
1 |
195,155,200 (GRCm38) |
missense |
probably damaging |
0.97 |
|
R6866:Cr2
|
UTSW |
1 |
195,151,691 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6915:Cr2
|
UTSW |
1 |
195,171,146 (GRCm38) |
missense |
probably benign |
0.06 |
|
R7057:Cr2
|
UTSW |
1 |
195,151,610 (GRCm38) |
missense |
possibly damaging |
0.83 |
|
R7117:Cr2
|
UTSW |
1 |
195,160,601 (GRCm38) |
missense |
possibly damaging |
0.79 |
|
R7200:Cr2
|
UTSW |
1 |
195,163,249 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7209:Cr2
|
UTSW |
1 |
195,168,724 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7350:Cr2
|
UTSW |
1 |
195,155,286 (GRCm38) |
missense |
probably benign |
0.21 |
|
R7414:Cr2
|
UTSW |
1 |
195,150,036 (GRCm38) |
missense |
probably benign |
|
|
R7453:Cr2
|
UTSW |
1 |
195,165,257 (GRCm38) |
splice site |
probably null |
|
|
R7479:Cr2
|
UTSW |
1 |
195,158,410 (GRCm38) |
critical splice donor site |
probably null |
|
|
R7480:Cr2
|
UTSW |
1 |
195,154,176 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7570:Cr2
|
UTSW |
1 |
195,169,340 (GRCm38) |
nonsense |
probably null |
|
|
R7666:Cr2
|
UTSW |
1 |
195,154,225 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7921:Cr2
|
UTSW |
1 |
195,151,667 (GRCm38) |
missense |
possibly damaging |
0.94 |
|
R7923:Cr2
|
UTSW |
1 |
195,168,687 (GRCm38) |
missense |
probably benign |
0.03 |
|
R8396:Cr2
|
UTSW |
1 |
195,158,068 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8503:Cr2
|
UTSW |
1 |
195,163,542 (GRCm38) |
missense |
probably benign |
|
|
R8517:Cr2
|
UTSW |
1 |
195,155,899 (GRCm38) |
missense |
probably benign |
0.03 |
|
R8773:Cr2
|
UTSW |
1 |
195,158,605 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8849:Cr2
|
UTSW |
1 |
195,157,239 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8896:Cr2
|
UTSW |
1 |
195,169,273 (GRCm38) |
missense |
possibly damaging |
0.58 |
|
R8938:Cr2
|
UTSW |
1 |
195,171,116 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R9027:Cr2
|
UTSW |
1 |
195,151,721 (GRCm38) |
missense |
probably benign |
0.08 |
|
R9045:Cr2
|
UTSW |
1 |
195,155,372 (GRCm38) |
missense |
possibly damaging |
0.61 |
|
R9116:Cr2
|
UTSW |
1 |
195,158,669 (GRCm38) |
nonsense |
probably null |
|
|
R9137:Cr2
|
UTSW |
1 |
195,168,332 (GRCm38) |
critical splice donor site |
probably null |
|
|
R9476:Cr2
|
UTSW |
1 |
195,158,108 (GRCm38) |
missense |
probably damaging |
0.97 |
|
R9497:Cr2
|
UTSW |
1 |
195,168,435 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R9510:Cr2
|
UTSW |
1 |
195,158,108 (GRCm38) |
missense |
probably damaging |
0.97 |
|
R9752:Cr2
|
UTSW |
1 |
195,141,267 (GRCm38) |
missense |
probably benign |
0.37 |
|
R9799:Cr2
|
UTSW |
1 |
195,160,680 (GRCm38) |
missense |
probably benign |
0.02 |
|
X0028:Cr2
|
UTSW |
1 |
195,149,982 (GRCm38) |
missense |
probably benign |
0.09 |
|
X0066:Cr2
|
UTSW |
1 |
195,166,321 (GRCm38) |
missense |
probably damaging |
0.99 |
|
Z1176:Cr2
|
UTSW |
1 |
195,154,153 (GRCm38) |
missense |
probably benign |
0.23 |
|
| Predicted Primers |
PCR Primer
(F):5'- ATAGGAGGAGCTTTATCCCAGGTGG -3'
(R):5'- TGTGTGTTTCCAACAGGCACTGAG -3'
Sequencing Primer
(F):5'- CTTTTCTCCAATGAGGCGGT -3'
(R):5'- ctgaggctgaaggaggatac -3'
|
| Posted On |
2013-07-11 |
Incidental Mutation