Mutagenetix > Incidental Mutations

Incidental Mutation 'PIT4585001:Clasp1'

556582

Institutional Source

Beutler Lab

Gene Symbol

Clasp1

Ensembl Gene

ENSMUSG00000064302

Gene Name

CLIP associating protein 1

Synonyms

1700030C23Rik, B130045P17Rik, CLASP1, mCLASP1, 5730583A19Rik, CLASP1alpha

Accession Numbers

Is this an essential gene?

Probably essential (E-score: 0.952) question?

Stock #

PIT4585001 (G1)

Quality Score

185.009

Status

Not validated

Chromosome

Chromosomal Location

118389058-118612678 bp(+) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

T to A at 118462555 bp

Zygosity

Heterozygous

Amino Acid Change

Asparagine to Lysine at position 156 (N156K)

Ref Sequence

ENSEMBL: ENSMUSP00000140019 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000049404] [ENSMUST00000070989] [ENSMUST00000165223] [ENSMUST00000178710] [ENSMUST00000185405] [ENSMUST00000186349] [ENSMUST00000187713] [ENSMUST00000188710] [ENSMUST00000189262] [ENSMUST00000189570] [ENSMUST00000189738] [ENSMUST00000190571] [ENSMUST00000190733] [ENSMUST00000191445]

Predicted Effect

probably damaging
Transcript: ENSMUST00000049404
AA Change: N156K

PolyPhen 2 Score 0.990 (Sensitivity: 0.72; Specificity: 0.97)

SMART Domains

Protein: ENSMUSP00000042266
Gene: ENSMUSG00000064302
AA Change: N156K

Domain	Start	End	E-Value	Type
TOG	1	232	7.31e-51	SMART
low complexity region	252	266	N/A	INTRINSIC
low complexity region	280	296	N/A	INTRINSIC
TOG	319	551	1.14e-11	SMART
low complexity region	579	594	N/A	INTRINSIC
low complexity region	606	633	N/A	INTRINSIC
low complexity region	674	707	N/A	INTRINSIC
low complexity region	751	763	N/A	INTRINSIC
low complexity region	821	831	N/A	INTRINSIC
TOG	847	1085	3.23e-1	SMART
low complexity region	1096	1113	N/A	INTRINSIC
low complexity region	1134	1147	N/A	INTRINSIC
low complexity region	1225	1236	N/A	INTRINSIC
TOG	1287	1525	4.96e-30	SMART

Predicted Effect

probably damaging
Transcript: ENSMUST00000070989
AA Change: N156K

PolyPhen 2 Score 0.989 (Sensitivity: 0.72; Specificity: 0.97)

SMART Domains

Protein: ENSMUSP00000067858
Gene: ENSMUSG00000064302
AA Change: N156K

Domain	Start	End	E-Value	Type
TOG	1	232	7.31e-51	SMART
low complexity region	252	266	N/A	INTRINSIC
low complexity region	280	296	N/A	INTRINSIC
TOG	319	551	1.14e-11	SMART
low complexity region	579	594	N/A	INTRINSIC
low complexity region	606	633	N/A	INTRINSIC
low complexity region	674	707	N/A	INTRINSIC
low complexity region	751	763	N/A	INTRINSIC
low complexity region	850	860	N/A	INTRINSIC
TOG	876	1114	3.23e-1	SMART
low complexity region	1125	1142	N/A	INTRINSIC
low complexity region	1215	1226	N/A	INTRINSIC
TOG	1277	1515	4.96e-30	SMART

Predicted Effect

probably damaging
Transcript: ENSMUST00000165223
AA Change: N156K

PolyPhen 2 Score 0.987 (Sensitivity: 0.73; Specificity: 0.96)

SMART Domains

Protein: ENSMUSP00000128089
Gene: ENSMUSG00000064302
AA Change: N156K

Domain	Start	End	E-Value	Type
TOG	1	232	7.31e-51	SMART
low complexity region	252	266	N/A	INTRINSIC
low complexity region	280	296	N/A	INTRINSIC
TOG	319	551	1.14e-11	SMART
low complexity region	579	594	N/A	INTRINSIC
low complexity region	606	633	N/A	INTRINSIC
low complexity region	684	714	N/A	INTRINSIC
low complexity region	792	802	N/A	INTRINSIC
TOG	818	1056	3.23e-1	SMART
low complexity region	1067	1084	N/A	INTRINSIC
low complexity region	1157	1168	N/A	INTRINSIC
TOG	1219	1457	4.96e-30	SMART

Predicted Effect

probably damaging
Transcript: ENSMUST00000178710
AA Change: N156K

PolyPhen 2 Score 0.993 (Sensitivity: 0.70; Specificity: 0.97)

SMART Domains

Protein: ENSMUSP00000137137
Gene: ENSMUSG00000064302
AA Change: N156K

Domain	Start	End	E-Value	Type
TOG	1	232	7.31e-51	SMART
low complexity region	252	266	N/A	INTRINSIC
low complexity region	280	296	N/A	INTRINSIC
TOG	319	551	1.14e-11	SMART
low complexity region	579	594	N/A	INTRINSIC
low complexity region	606	633	N/A	INTRINSIC
low complexity region	668	698	N/A	INTRINSIC
low complexity region	752	766	N/A	INTRINSIC
low complexity region	784	794	N/A	INTRINSIC
TOG	810	1047	6.55e-2	SMART
low complexity region	1058	1075	N/A	INTRINSIC
low complexity region	1148	1159	N/A	INTRINSIC
TOG	1210	1448	4.96e-30	SMART

Predicted Effect

probably damaging
Transcript: ENSMUST00000185405
AA Change: N156K

PolyPhen 2 Score 0.995 (Sensitivity: 0.68; Specificity: 0.97)

SMART Domains

Protein: ENSMUSP00000139619
Gene: ENSMUSG00000064302
AA Change: N156K

Domain	Start	End	E-Value	Type
TOG	1	232	3.4e-55	SMART
low complexity region	252	266	N/A	INTRINSIC
low complexity region	280	296	N/A	INTRINSIC
TOG	319	551	5.5e-16	SMART
low complexity region	579	594	N/A	INTRINSIC
low complexity region	606	633	N/A	INTRINSIC
low complexity region	682	715	N/A	INTRINSIC
low complexity region	769	783	N/A	INTRINSIC
low complexity region	801	811	N/A	INTRINSIC
TOG	827	1065	1.6e-5	SMART
low complexity region	1076	1093	N/A	INTRINSIC
low complexity region	1166	1177	N/A	INTRINSIC
TOG	1228	1466	2.3e-34	SMART

Predicted Effect

probably damaging
Transcript: ENSMUST00000186349
AA Change: N156K

PolyPhen 2 Score 0.990 (Sensitivity: 0.72; Specificity: 0.97)

SMART Domains

Protein: ENSMUSP00000141105
Gene: ENSMUSG00000064302
AA Change: N156K

Domain	Start	End	E-Value	Type
TOG	1	232	7.31e-51	SMART
low complexity region	252	266	N/A	INTRINSIC
low complexity region	280	296	N/A	INTRINSIC
TOG	319	551	1.14e-11	SMART
low complexity region	579	594	N/A	INTRINSIC
low complexity region	606	633	N/A	INTRINSIC
low complexity region	674	707	N/A	INTRINSIC
low complexity region	751	763	N/A	INTRINSIC
low complexity region	821	831	N/A	INTRINSIC
TOG	847	1085	3.23e-1	SMART
low complexity region	1096	1113	N/A	INTRINSIC
low complexity region	1134	1147	N/A	INTRINSIC
low complexity region	1225	1236	N/A	INTRINSIC
TOG	1287	1525	4.96e-30	SMART

Predicted Effect

probably damaging
Transcript: ENSMUST00000187713
AA Change: N156K

PolyPhen 2 Score 0.997 (Sensitivity: 0.41; Specificity: 0.98)

SMART Domains

Protein: ENSMUSP00000139526
Gene: ENSMUSG00000064302
AA Change: N156K

Domain	Start	End	E-Value	Type
TOG	1	232	3.4e-55	SMART
low complexity region	252	266	N/A	INTRINSIC
low complexity region	280	296	N/A	INTRINSIC
TOG	319	551	5.5e-16	SMART
low complexity region	579	594	N/A	INTRINSIC
low complexity region	606	633	N/A	INTRINSIC
low complexity region	684	714	N/A	INTRINSIC
low complexity region	768	782	N/A	INTRINSIC
low complexity region	800	810	N/A	INTRINSIC
TOG	826	1064	1.6e-5	SMART
low complexity region	1075	1092	N/A	INTRINSIC
low complexity region	1165	1176	N/A	INTRINSIC
TOG	1227	1465	2.3e-34	SMART

Predicted Effect

probably damaging
Transcript: ENSMUST00000188710
AA Change: N156K

PolyPhen 2 Score 0.990 (Sensitivity: 0.72; Specificity: 0.97)

SMART Domains

Protein: ENSMUSP00000140593
Gene: ENSMUSG00000064302
AA Change: N156K

Domain	Start	End	E-Value	Type
TOG	1	232	3.4e-55	SMART
low complexity region	252	266	N/A	INTRINSIC
low complexity region	280	296	N/A	INTRINSIC
TOG	319	551	5.5e-16	SMART
low complexity region	579	594	N/A	INTRINSIC
low complexity region	606	633	N/A	INTRINSIC
low complexity region	674	707	N/A	INTRINSIC
low complexity region	751	763	N/A	INTRINSIC
low complexity region	818	832	N/A	INTRINSIC
low complexity region	850	860	N/A	INTRINSIC
TOG	876	1114	1.6e-5	SMART
low complexity region	1125	1142	N/A	INTRINSIC
low complexity region	1215	1226	N/A	INTRINSIC
TOG	1277	1515	2.3e-34	SMART

Predicted Effect

probably damaging
Transcript: ENSMUST00000189262
AA Change: N156K

PolyPhen 2 Score 0.987 (Sensitivity: 0.73; Specificity: 0.96)

SMART Domains

Protein: ENSMUSP00000140860
Gene: ENSMUSG00000064302
AA Change: N156K

Domain	Start	End	E-Value	Type
TOG	1	232	3.4e-55	SMART
low complexity region	252	266	N/A	INTRINSIC
low complexity region	280	296	N/A	INTRINSIC
TOG	319	551	5.5e-16	SMART
low complexity region	579	594	N/A	INTRINSIC
low complexity region	606	633	N/A	INTRINSIC
low complexity region	668	698	N/A	INTRINSIC
low complexity region	776	786	N/A	INTRINSIC
TOG	802	1040	1.6e-5	SMART
low complexity region	1051	1068	N/A	INTRINSIC
low complexity region	1141	1152	N/A	INTRINSIC
TOG	1203	1441	2.3e-34	SMART

Predicted Effect

probably damaging
Transcript: ENSMUST00000189570
AA Change: N156K

PolyPhen 2 Score 0.993 (Sensitivity: 0.70; Specificity: 0.97)

SMART Domains

Protein: ENSMUSP00000140167
Gene: ENSMUSG00000064302
AA Change: N156K

Domain	Start	End	E-Value	Type
TOG	1	232	3.4e-55	SMART
low complexity region	252	266	N/A	INTRINSIC
low complexity region	280	296	N/A	INTRINSIC
TOG	319	551	5.5e-16	SMART
low complexity region	579	594	N/A	INTRINSIC
low complexity region	606	633	N/A	INTRINSIC
low complexity region	684	714	N/A	INTRINSIC
low complexity region	792	802	N/A	INTRINSIC
TOG	818	1055	3.2e-6	SMART
low complexity region	1066	1083	N/A	INTRINSIC
low complexity region	1156	1167	N/A	INTRINSIC
TOG	1218	1456	2.3e-34	SMART

Predicted Effect

probably damaging
Transcript: ENSMUST00000189738
AA Change: N156K

PolyPhen 2 Score 0.989 (Sensitivity: 0.72; Specificity: 0.97)

SMART Domains

Protein: ENSMUSP00000140665
Gene: ENSMUSG00000064302
AA Change: N156K

Domain	Start	End	E-Value	Type
TOG	1	232	7.31e-51	SMART
low complexity region	252	266	N/A	INTRINSIC
low complexity region	280	296	N/A	INTRINSIC
TOG	319	551	1.14e-11	SMART
low complexity region	579	594	N/A	INTRINSIC
low complexity region	606	633	N/A	INTRINSIC
low complexity region	668	698	N/A	INTRINSIC
low complexity region	752	766	N/A	INTRINSIC
low complexity region	784	794	N/A	INTRINSIC
TOG	810	1048	3.23e-1	SMART
low complexity region	1059	1076	N/A	INTRINSIC
low complexity region	1149	1160	N/A	INTRINSIC
TOG	1211	1449	4.96e-30	SMART

Predicted Effect

probably damaging
Transcript: ENSMUST00000190571
AA Change: N156K

PolyPhen 2 Score 0.990 (Sensitivity: 0.72; Specificity: 0.97)

SMART Domains

Protein: ENSMUSP00000140019
Gene: ENSMUSG00000064302
AA Change: N156K

Domain	Start	End	E-Value	Type
TOG	1	232	3.4e-55	SMART
low complexity region	252	266	N/A	INTRINSIC
low complexity region	280	296	N/A	INTRINSIC
TOG	319	551	5.5e-16	SMART
low complexity region	579	594	N/A	INTRINSIC
low complexity region	606	633	N/A	INTRINSIC
low complexity region	682	715	N/A	INTRINSIC
low complexity region	759	771	N/A	INTRINSIC
low complexity region	805	819	N/A	INTRINSIC
low complexity region	837	847	N/A	INTRINSIC
TOG	863	1101	1.6e-5	SMART
low complexity region	1112	1129	N/A	INTRINSIC
low complexity region	1150	1163	N/A	INTRINSIC
low complexity region	1241	1252	N/A	INTRINSIC
TOG	1303	1541	2.3e-34	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000190733

Predicted Effect

probably damaging
Transcript: ENSMUST00000191445
AA Change: N156K

PolyPhen 2 Score 0.997 (Sensitivity: 0.41; Specificity: 0.98)

SMART Domains

Protein: ENSMUSP00000140095
Gene: ENSMUSG00000064302
AA Change: N156K

Domain	Start	End	E-Value	Type
TOG	1	232	3.4e-55	SMART
low complexity region	252	266	N/A	INTRINSIC
low complexity region	280	296	N/A	INTRINSIC
TOG	319	551	5.5e-16	SMART
low complexity region	579	594	N/A	INTRINSIC
low complexity region	606	633	N/A	INTRINSIC
low complexity region	674	707	N/A	INTRINSIC
low complexity region	761	775	N/A	INTRINSIC
low complexity region	793	803	N/A	INTRINSIC
TOG	819	1056	3.2e-6	SMART
low complexity region	1067	1084	N/A	INTRINSIC
low complexity region	1157	1168	N/A	INTRINSIC
TOG	1219	1457	2.3e-34	SMART

Coding Region Coverage

1x: 93.6%
3x: 91.2%
10x: 86.5%
20x: 76.8%

Validation Efficiency

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] CLASPs, such as CLASP1, are nonmotor microtubule-associated proteins that interact with CLIPs (e.g., CLIP170; MIM 179838). CLASP1 is involved in the regulation of microtubule dynamics at the kinetochore and throughout the spindle (Maiato et al., 2003 [PubMed 12837247]).[supplied by OMIM, Mar 2008]

Allele List at MGI

Other mutations in this stock

Total: 55 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Aurka	T	C	2: 172,357,197	M318V	probably benign	Het
Cacna2d1	T	A	5: 16,326,344	D560E	probably damaging	Het
Ccdc148	T	A	2: 58,982,976	T202S	probably benign	Het
Ccdc155	C	T	7: 45,200,271	G76D	probably benign	Het
Cdc42bpb	T	C	12: 111,304,978	D1149G	probably damaging	Het
Cox18	G	A	5: 90,217,575	T255I	possibly damaging	Het
Cse1l	A	G	2: 166,941,474	T783A	probably damaging	Het
Dnajc16	T	C	4: 141,764,685	Y609C	probably damaging	Het
Doc2g	A	G	19: 4,006,630	T339A	probably benign	Het
Eif5a	T	C	11: 69,918,070		probably benign	Het
Epha3	A	G	16: 63,566,577		probably null	Het
Esco1	A	T	18: 10,594,355	C310*	probably null	Het
Fam208b	G	A	13: 3,574,979	A1657V	possibly damaging	Het
Fam222a	A	G	5: 114,611,040	Y99C	probably damaging	Het
Fzd2	T	C	11: 102,605,747	L339P	probably damaging	Het
Gfral	A	T	9: 76,197,294	N145K	probably damaging	Het
Gga1	T	A	15: 78,893,790	N618K	probably benign	Het
Gpatch3	T	A	4: 133,583,086	H447Q	probably damaging	Het
Gpn1	A	T	5: 31,509,403	R346*	probably null	Het
Gsg1	T	C	6: 135,237,560	E317G	probably benign	Het
Gsk3b	A	G	16: 38,184,454	N129S	probably damaging	Het
Hmg20b	G	T	10: 81,348,955	D94E	possibly damaging	Het
Klhdc9	T	A	1: 171,359,818	H204L	possibly damaging	Het
Klhl24	A	G	16: 20,106,888	I55M	probably benign	Het
Kmt2c	T	C	5: 25,315,106	D2002G	probably benign	Het
Lama4	A	G	10: 39,074,746	N1015S	probably damaging	Het
Lpp	T	C	16: 24,761,947	C263R	probably benign	Het
Lrp1b	T	C	2: 41,269,204	I1689V		Het
Mipep	C	A	14: 60,784,835	Q50K	probably benign	Het
Mx1	T	C	16: 97,456,254	D101G	probably benign	Het
Nabp2	C	G	10: 128,408,807	E37Q	possibly damaging	Het
Nme6	A	G	9: 109,842,036	I115V	possibly damaging	Het
Nup93	A	T	8: 94,243,727	T85S	probably benign	Het
Oit3	T	A	10: 59,431,013	I224F	possibly damaging	Het
Parp14	T	C	16: 35,858,605	K331R	probably benign	Het
Pls1	T	A	9: 95,761,390	T519S	probably benign	Het
Rcn3	A	G	7: 45,086,694	F197L	probably benign	Het
Rnf213	C	T	11: 119,458,392	T3773I		Het
Rprd1b	A	T	2: 158,047,957	I153L	probably benign	Het
Scel	A	G	14: 103,592,368	D462G	possibly damaging	Het
Sh3bp1	C	T	15: 78,910,076	S548L	possibly damaging	Het
Sim1	T	A	10: 50,984,188	Y715*	probably null	Het
Slc18a2	A	T	19: 59,293,861	Q500L	possibly damaging	Het
Slc5a8	T	G	10: 88,886,503	M66R	probably damaging	Het
Slco1a6	T	C	6: 142,109,520	T233A	probably damaging	Het
Smu1	T	C	4: 40,739,623	T396A	probably benign	Het
Tas2r104	T	C	6: 131,685,558	T63A	possibly damaging	Het
Top2a	C	T	11: 99,001,373	A1088T	probably benign	Het
Ucp1	T	C	8: 83,293,948	F129S	probably damaging	Het
Unc13b	T	A	4: 43,091,298	D41E	probably benign	Het
Usp10	T	G	8: 119,954,892	V696G	probably benign	Het
Xylt2	C	T	11: 94,666,240	V745M	probably damaging	Het
Zbtb49	A	T	5: 38,216,476	N41K	probably damaging	Het
Zfp109	T	A	7: 24,229,354	D218V	probably benign	Het
Zfp420	G	A	7: 29,876,005	R550Q	probably benign	Het

Other mutations in Clasp1

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01785:Clasp1	APN	1	118497736	missense	possibly damaging	0.74
IGL01786:Clasp1	APN	1	118497736	missense	possibly damaging	0.74
IGL01871:Clasp1	APN	1	118570889	missense	probably damaging	1.00
IGL02066:Clasp1	APN	1	118565260	critical splice donor site	probably null
IGL02602:Clasp1	APN	1	118471785	missense	probably damaging	0.99
IGL02683:Clasp1	APN	1	118539266	missense	probably benign	0.33
IGL02728:Clasp1	APN	1	118602377	missense	probably damaging	1.00
IGL02820:Clasp1	APN	1	118551104	missense	possibly damaging	0.77
IGL02874:Clasp1	APN	1	118552043	missense	possibly damaging	0.86
IGL02975:Clasp1	APN	1	118462547	missense	probably damaging	1.00
IGL03100:Clasp1	APN	1	118467896	missense	possibly damaging	0.79
IGL03115:Clasp1	APN	1	118501323	nonsense	probably null
IGL03122:Clasp1	APN	1	118510277	missense	probably damaging	1.00
IGL03180:Clasp1	APN	1	118505525	missense	probably benign	0.33
IGL03248:Clasp1	APN	1	118602476	missense	probably benign	0.01
IGL03388:Clasp1	APN	1	118505503	missense	possibly damaging	0.95
F5770:Clasp1	UTSW	1	118581348	missense	probably damaging	1.00
I2288:Clasp1	UTSW	1	118565229	missense	probably benign	0.09
R0079:Clasp1	UTSW	1	118543304	missense	probably damaging	1.00
R0395:Clasp1	UTSW	1	118539331	missense	possibly damaging	0.48
R0960:Clasp1	UTSW	1	118552026	missense	probably benign	0.39
R1448:Clasp1	UTSW	1	118508916	missense	probably benign	0.01
R1497:Clasp1	UTSW	1	118552058	missense	probably benign	0.42
R1607:Clasp1	UTSW	1	118504959	missense	probably damaging	0.98
R1722:Clasp1	UTSW	1	118590464	missense	probably damaging	1.00
R1758:Clasp1	UTSW	1	118548025	missense	probably damaging	1.00
R1765:Clasp1	UTSW	1	118505531	missense	probably damaging	0.99
R1855:Clasp1	UTSW	1	118508894	missense	probably damaging	1.00
R1861:Clasp1	UTSW	1	118570931	missense	possibly damaging	0.93
R1874:Clasp1	UTSW	1	118600585	critical splice donor site	probably null
R1942:Clasp1	UTSW	1	118501348	missense	possibly damaging	0.94
R2025:Clasp1	UTSW	1	118504899	missense	probably damaging	1.00
R2174:Clasp1	UTSW	1	118560095	missense	probably damaging	1.00
R2280:Clasp1	UTSW	1	118565183	missense	probably benign	0.05
R2288:Clasp1	UTSW	1	118578878	missense	probably benign
R2895:Clasp1	UTSW	1	118459838	missense	probably damaging	1.00
R3958:Clasp1	UTSW	1	118467881	missense	probably damaging	0.99
R4073:Clasp1	UTSW	1	118503848	missense	probably damaging	1.00
R4206:Clasp1	UTSW	1	118578906	missense	probably damaging	1.00
R4465:Clasp1	UTSW	1	118561078	missense	probably damaging	1.00
R4609:Clasp1	UTSW	1	118503035	intron	probably benign
R4679:Clasp1	UTSW	1	118543271	missense	probably damaging	0.99
R4707:Clasp1	UTSW	1	118543197	nonsense	probably null
R4809:Clasp1	UTSW	1	118461250	missense	probably benign	0.00
R4906:Clasp1	UTSW	1	118508910	nonsense	probably null
R5048:Clasp1	UTSW	1	118547610	intron	probably benign
R5298:Clasp1	UTSW	1	118547920	missense	possibly damaging	0.71
R5485:Clasp1	UTSW	1	118467913	missense	possibly damaging	0.95
R5516:Clasp1	UTSW	1	118497721	missense	probably damaging	1.00
R5821:Clasp1	UTSW	1	118590484	missense	probably damaging	1.00
R5911:Clasp1	UTSW	1	118506908	unclassified	probably benign
R6092:Clasp1	UTSW	1	118510298	missense	probably damaging	0.97
R6181:Clasp1	UTSW	1	118419817	missense	probably benign	0.18
R6478:Clasp1	UTSW	1	118512180	nonsense	probably null
R7090:Clasp1	UTSW	1	118482086	missense	probably benign	0.45
R7216:Clasp1	UTSW	1	118547918	missense	probably benign	0.00
R7508:Clasp1	UTSW	1	118545434	missense	probably benign	0.30
R7541:Clasp1	UTSW	1	118542997	splice site	probably null
R7644:Clasp1	UTSW	1	118512750	splice site	probably null
R7825:Clasp1	UTSW	1	118545393	missense	probably benign	0.00
R7910:Clasp1	UTSW	1	118602414	nonsense	probably null
R7971:Clasp1	UTSW	1	118521829	missense	probably damaging	0.99
R8074:Clasp1	UTSW	1	118462483	missense	probably benign
R8344:Clasp1	UTSW	1	118503899	missense	probably damaging	1.00
V7581:Clasp1	UTSW	1	118581348	missense	probably damaging	1.00
X0028:Clasp1	UTSW	1	118551125	missense	possibly damaging	0.93

Predicted Primers

PCR Primer
(F):5'- AGAGCTCTTGTTTTGATGACTCCTG -3'
(R):5'- CCAAGGGGCTAGAAATGTGATTC -3'

Sequencing Primer
(F):5'- ATGACTCCTGTCTTACTGTGAAGAG -3'
(R):5'- GCCAGTAATCTCAGCTGTTAAGG -3'

Posted On

2019-06-07