Mutagenetix > Incidental Mutation

Incidental Mutation 'R0586:Fcgbp'

55758

Institutional Source

Beutler Lab

Gene Symbol

Fcgbp

Ensembl Gene

ENSMUSG00000047730

Gene Name

Fc fragment of IgG binding protein

Synonyms

A430096B05Rik

MMRRC Submission

038776-MU

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

R0586 (G1)

Quality Score

225

Status

Validated

Chromosome

Chromosomal Location

28071236-28120862 bp(+) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

A to T at 28089713 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Aspartic acid to Valine at position 568 (D568V)

Ref Sequence

ENSEMBL: ENSMUSP00000114271 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000076648] [ENSMUST00000138392]

AlphaFold

E9Q0B5

Predicted Effect

probably benign
Transcript: ENSMUST00000076648
AA Change: D568V

PolyPhen 2 Score 0.250 (Sensitivity: 0.91; Specificity: 0.88)

SMART Domains

Protein: ENSMUSP00000075945
Gene: ENSMUSG00000047730
AA Change: D568V

Domain	Start	End	E-Value	Type
signal peptide	1	26	N/A	INTRINSIC
FOLN	27	49	2.3e-4	SMART
VWD	46	211	5.26e-45	SMART
low complexity region	226	237	N/A	INTRINSIC
C8	251	326	1.17e-34	SMART
Pfam:TIL	329	383	1.2e-12	PFAM
VWC	385	431	2.34e-1	SMART
FOLN	418	441	3.48e1	SMART
VWD	438	603	6.85e-35	SMART
C8	642	717	1.4e-32	SMART
Pfam:TIL	720	773	4.7e-14	PFAM
VWC	775	829	9.42e-1	SMART
VWD	824	990	7.86e-44	SMART
C8	1034	1109	1.66e-34	SMART
Pfam:TIL	1112	1165	6.7e-13	PFAM
VWC	1167	1225	9.8e-3	SMART
FOLN	1198	1220	9.55e-1	SMART
FOLN	1224	1246	2.41e0	SMART
VWD	1243	1411	6.59e-37	SMART
C8	1451	1527	5.6e-32	SMART
low complexity region	1541	1551	N/A	INTRINSIC
EGF_like	1558	1581	6.15e1	SMART
VWC	1589	1682	1.6e-2	SMART
VWD	1640	1807	5.15e-39	SMART
C8	1839	1914	4.62e-33	SMART
EGF_like	1942	1965	4.46e1	SMART
VWC	1972	2064	1.92e-1	SMART
VWD	2024	2180	6.34e-39	SMART
low complexity region	2201	2214	N/A	INTRINSIC
C8	2221	2296	3.7e-32	SMART
Pfam:TIL	2299	2352	5e-12	PFAM
VWC	2354	2413	8.29e-1	SMART
FOLN	2385	2407	4.96e1	SMART
VWD	2404	2566	1.89e-5	SMART

Predicted Effect

probably damaging
Transcript: ENSMUST00000138392
AA Change: D568V

PolyPhen 2 Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)

SMART Domains

Protein: ENSMUSP00000114271
Gene: ENSMUSG00000047730
AA Change: D568V

Domain	Start	End	E-Value	Type
signal peptide	1	26	N/A	INTRINSIC
FOLN	27	49	2.3e-4	SMART
VWD	46	211	5.26e-45	SMART
low complexity region	226	237	N/A	INTRINSIC
C8	251	326	1.17e-34	SMART
Pfam:TIL	329	383	8.4e-13	PFAM
VWC	385	431	2.34e-1	SMART
FOLN	418	441	3.48e1	SMART
VWD	438	603	7.99e-36	SMART
C8	642	717	1.4e-32	SMART
Pfam:TIL	720	773	3.3e-14	PFAM
VWC	775	829	9.42e-1	SMART
VWD	824	990	7.86e-44	SMART
C8	1034	1109	1.66e-34	SMART
Pfam:TIL	1112	1165	6.9e-13	PFAM
VWC	1167	1225	9.8e-3	SMART
FOLN	1198	1220	9.55e-1	SMART
FOLN	1224	1246	2.41e0	SMART
VWD	1243	1411	6.59e-37	SMART
C8	1451	1527	5.6e-32	SMART
low complexity region	1541	1551	N/A	INTRINSIC
EGF_like	1558	1581	6.15e1	SMART
VWC	1589	1682	1.6e-2	SMART
VWD	1640	1807	5.15e-39	SMART
C8	1839	1914	4.62e-33	SMART
EGF_like	1942	1965	4.46e1	SMART
VWC	1972	2064	1.92e-1	SMART
VWD	2024	2180	6.34e-39	SMART
low complexity region	2201	2214	N/A	INTRINSIC
C8	2221	2296	3.7e-32	SMART
Pfam:TIL	2299	2352	1e-11	PFAM
VWC	2354	2413	8.29e-1	SMART
FOLN	2385	2407	4.96e1	SMART
VWD	2404	2566	1.89e-5	SMART

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000140004

Meta Mutation Damage Score

0.6467

Coding Region Coverage

1x: 99.7%
3x: 99.1%
10x: 97.5%
20x: 94.4%

Validation Efficiency

100% (74/74)

Allele List at MGI

Other mutations in this stock

Total: 69 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Abca1	A	T	4: 53,092,860 (GRCm38)	V308E	probably benign	Het
Amy1	A	G	3: 113,562,769 (GRCm38)		probably benign	Het
Astn2	C	T	4: 66,185,142 (GRCm38)	V345M	unknown	Het
Brwd1	T	C	16: 96,043,086 (GRCm38)	E756G	probably damaging	Het
Ccpg1	C	T	9: 73,001,821 (GRCm38)	L135F	probably benign	Het
Cecr2	C	T	6: 120,757,884 (GRCm38)	H694Y	probably damaging	Het
Cfh	G	A	1: 140,183,182 (GRCm38)	T14I	probably damaging	Het
Cfhr2	G	A	1: 139,813,434 (GRCm38)	R268*	probably null	Het
Clca1	T	A	3: 145,032,589 (GRCm38)	I53L	probably benign	Het
Clcn6	A	G	4: 148,038,749 (GRCm38)		probably benign	Het
Cnfn	C	T	7: 25,367,831 (GRCm38)	V98I	probably benign	Het
Cntnap1	C	T	11: 101,187,014 (GRCm38)	R1122W	probably damaging	Het
Cpne9	A	T	6: 113,295,063 (GRCm38)	E384V	probably damaging	Het
Ctr9	T	C	7: 111,049,498 (GRCm38)		probably benign	Het
Ctsj	T	A	13: 61,003,701 (GRCm38)		probably benign	Het
Cyp2c39	A	C	19: 39,513,490 (GRCm38)		probably benign	Het
Dock5	A	C	14: 67,809,032 (GRCm38)	I767S	probably damaging	Het
Eftud2	T	C	11: 102,846,620 (GRCm38)	T552A	probably damaging	Het
Epdr1	A	G	13: 19,594,545 (GRCm38)	I25T	probably damaging	Het
Fcgbpl1	T	A	7: 28,137,091 (GRCm38)	V145D	probably damaging	Het
Fhip1b	T	C	7: 105,389,447 (GRCm38)	E195G	probably damaging	Het
Frem2	T	A	3: 53,647,921 (GRCm38)	T1732S	probably damaging	Het
Fuz	T	C	7: 44,898,558 (GRCm38)	V183A	possibly damaging	Het
Grb7	T	C	11: 98,453,220 (GRCm38)	S284P	probably damaging	Het
Hoxb4	G	T	11: 96,318,887 (GRCm38)	G40C	probably damaging	Het
Kcnn1	T	C	8: 70,863,869 (GRCm38)		probably benign	Het
Kmt2d	C	A	15: 98,835,207 (GRCm38)		probably benign	Het
L3mbtl3	A	G	10: 26,327,834 (GRCm38)	V366A	unknown	Het
Ldlr	G	A	9: 21,739,744 (GRCm38)	R486H	probably benign	Het
Lnpep	A	T	17: 17,575,396 (GRCm38)		probably benign	Het
Mical3	A	T	6: 121,029,641 (GRCm38)		probably benign	Het
Myh15	T	C	16: 49,171,887 (GRCm38)		probably benign	Het
Nup155	T	A	15: 8,130,232 (GRCm38)	H542Q	probably benign	Het
Opn4	A	G	14: 34,598,973 (GRCm38)		probably benign	Het
Or13a20	T	C	7: 140,652,063 (GRCm38)	F28S	probably benign	Het
Or4a68	T	A	2: 89,439,354 (GRCm38)	R308S	possibly damaging	Het
Or6c68	A	G	10: 129,322,047 (GRCm38)	I141M	probably benign	Het
Or8g4	A	T	9: 39,751,118 (GRCm38)	H244L	probably damaging	Het
Or8h10	T	C	2: 86,978,782 (GRCm38)	N5D	probably damaging	Het
Pak3	TTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTC	TTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTC	X: 143,743,893 (GRCm38)		probably benign	Het
Parp14	T	C	16: 35,841,012 (GRCm38)	K1522R	probably benign	Het
Pkhd1	A	T	1: 20,524,111 (GRCm38)	D1259E	probably benign	Het
Pogz	C	T	3: 94,879,353 (GRCm38)	A1084V	probably damaging	Het
Popdc3	G	A	10: 45,315,263 (GRCm38)	V157M	probably benign	Het
Prrt4	T	C	6: 29,171,184 (GRCm38)	Y423C	probably damaging	Het
Qrich1	C	T	9: 108,534,520 (GRCm38)	H415Y	probably damaging	Het
Rabgap1	A	G	2: 37,543,223 (GRCm38)	N801D	probably benign	Het
Rb1	A	G	14: 73,287,684 (GRCm38)		probably benign	Het
Rp1	A	T	1: 4,347,837 (GRCm38)	N1017K	possibly damaging	Het
Ryr2	T	C	13: 11,635,559 (GRCm38)	D356G	probably null	Het
Skint8	C	G	4: 111,936,929 (GRCm38)	P172R	probably damaging	Het
Slc12a8	T	G	16: 33,658,230 (GRCm38)	M643R	possibly damaging	Het
Sult1c1	A	T	17: 53,964,085 (GRCm38)		probably benign	Het
Tasor2	A	G	13: 3,590,321 (GRCm38)	L272P	probably damaging	Het
Tcaf1	T	A	6: 42,673,539 (GRCm38)	M869L	probably damaging	Het
Tecpr1	T	C	5: 144,217,401 (GRCm38)	N78S	probably damaging	Het
Tectb	A	T	19: 55,181,924 (GRCm38)	Y69F	probably damaging	Het
Them4	A	T	3: 94,329,794 (GRCm38)	N187I	possibly damaging	Het
Tm9sf3	A	G	19: 41,256,143 (GRCm38)		probably null	Het
Tnik	G	T	3: 28,577,361 (GRCm38)		probably benign	Het
Tns2	G	T	15: 102,109,585 (GRCm38)		probably benign	Het
Tnxb	A	G	17: 34,672,144 (GRCm38)	D487G	probably damaging	Het
Trim33	T	A	3: 103,310,344 (GRCm38)	C202S	probably damaging	Het
Trpm2	T	A	10: 77,923,516 (GRCm38)	I1145F	probably damaging	Het
Trpv2	A	G	11: 62,592,770 (GRCm38)	T478A	probably benign	Het
Ube2e3	T	C	2: 78,919,990 (GRCm38)	Y187H	probably benign	Het
Ubxn11	A	G	4: 134,109,652 (GRCm38)	R64G	possibly damaging	Het
Wwtr1	T	C	3: 57,459,066 (GRCm38)	T407A	probably damaging	Het
Zfyve26	A	T	12: 79,268,728 (GRCm38)	S1325T	possibly damaging	Het

Other mutations in Fcgbp

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00309:Fcgbp	APN	7	28,085,130 (GRCm38)	missense	probably damaging	1.00
IGL00331:Fcgbp	APN	7	28,101,541 (GRCm38)	splice site	probably benign
IGL00335:Fcgbp	APN	7	28,086,135 (GRCm38)	missense	possibly damaging	0.90
IGL00470:Fcgbp	APN	7	28,075,086 (GRCm38)	nonsense	probably null
IGL00491:Fcgbp	APN	7	28,093,402 (GRCm38)	missense	probably damaging	1.00
IGL00498:Fcgbp	APN	7	28,091,797 (GRCm38)	missense	probably damaging	1.00
IGL01296:Fcgbp	APN	7	28,089,647 (GRCm38)	missense	probably benign	0.15
IGL01582:Fcgbp	APN	7	28,093,642 (GRCm38)	missense	probably benign	0.19
IGL01929:Fcgbp	APN	7	28,103,963 (GRCm38)	missense	probably damaging	1.00
IGL02024:Fcgbp	APN	7	28,106,374 (GRCm38)	missense	probably damaging	1.00
IGL02027:Fcgbp	APN	7	28,075,204 (GRCm38)	missense	probably damaging	1.00
IGL02140:Fcgbp	APN	7	28,091,954 (GRCm38)	missense	probably damaging	1.00
IGL02162:Fcgbp	APN	7	28,075,235 (GRCm38)	missense	probably damaging	1.00
IGL02345:Fcgbp	APN	7	28,071,643 (GRCm38)	splice site	probably benign
IGL02377:Fcgbp	APN	7	28,106,970 (GRCm38)	missense	possibly damaging	0.67
IGL02389:Fcgbp	APN	7	28,075,171 (GRCm38)	missense	probably damaging	1.00
IGL02423:Fcgbp	APN	7	28,089,953 (GRCm38)	missense	probably benign	0.02
IGL02523:Fcgbp	APN	7	28,104,732 (GRCm38)	missense	possibly damaging	0.89
IGL02561:Fcgbp	APN	7	28,101,174 (GRCm38)	intron	probably benign
IGL02631:Fcgbp	APN	7	28,085,298 (GRCm38)	missense	probably damaging	1.00
IGL02716:Fcgbp	APN	7	28,101,434 (GRCm38)	missense	probably damaging	0.98
IGL02836:Fcgbp	APN	7	28,117,358 (GRCm38)	missense	possibly damaging	0.91
IGL02957:Fcgbp	APN	7	28,091,847 (GRCm38)	nonsense	probably null
IGL02971:Fcgbp	APN	7	28,101,473 (GRCm38)	missense	probably damaging	1.00
IGL03284:Fcgbp	APN	7	28,085,432 (GRCm38)	missense	possibly damaging	0.93
IGL03379:Fcgbp	APN	7	28,089,917 (GRCm38)	missense	possibly damaging	0.76
bilge	UTSW	7	28,117,337 (GRCm38)	missense	probably benign	0.00
R6548_fcgbp_365	UTSW	7	28,091,918 (GRCm38)	missense	probably benign	0.00
swill	UTSW	7	28,089,734 (GRCm38)	missense	probably damaging	1.00
G1citation:Fcgbp	UTSW	7	28,107,356 (GRCm38)	missense	probably damaging	1.00
IGL02796:Fcgbp	UTSW	7	28,101,151 (GRCm38)	intron	probably benign
PIT4486001:Fcgbp	UTSW	7	28,075,273 (GRCm38)	missense	possibly damaging	0.52
R0277:Fcgbp	UTSW	7	28,085,493 (GRCm38)	critical splice donor site	probably null
R0387:Fcgbp	UTSW	7	28,091,454 (GRCm38)	splice site	probably benign
R0981:Fcgbp	UTSW	7	28,085,110 (GRCm38)	nonsense	probably null
R0987:Fcgbp	UTSW	7	28,094,174 (GRCm38)	missense	probably damaging	1.00
R1240:Fcgbp	UTSW	7	28,120,525 (GRCm38)	missense	probably damaging	1.00
R1394:Fcgbp	UTSW	7	28,093,379 (GRCm38)	missense	probably damaging	0.98
R1395:Fcgbp	UTSW	7	28,093,379 (GRCm38)	missense	probably damaging	0.98
R1438:Fcgbp	UTSW	7	28,103,733 (GRCm38)	nonsense	probably null
R1474:Fcgbp	UTSW	7	28,091,848 (GRCm38)	missense	probably benign	0.00
R1521:Fcgbp	UTSW	7	28,075,160 (GRCm38)	missense	probably benign	0.00
R1740:Fcgbp	UTSW	7	28,101,249 (GRCm38)	missense	possibly damaging	0.87
R1750:Fcgbp	UTSW	7	28,093,443 (GRCm38)	nonsense	probably null
R1772:Fcgbp	UTSW	7	28,105,175 (GRCm38)	missense	possibly damaging	0.90
R1804:Fcgbp	UTSW	7	28,086,139 (GRCm38)	missense	probably benign
R1808:Fcgbp	UTSW	7	28,085,090 (GRCm38)	missense	probably benign	0.04
R1819:Fcgbp	UTSW	7	28,085,283 (GRCm38)	missense	probably benign	0.00
R1934:Fcgbp	UTSW	7	28,107,093 (GRCm38)	missense	probably damaging	1.00
R1972:Fcgbp	UTSW	7	28,094,192 (GRCm38)	missense	probably benign	0.11
R2051:Fcgbp	UTSW	7	28,120,360 (GRCm38)	missense	probably damaging	0.97
R2072:Fcgbp	UTSW	7	28,120,389 (GRCm38)	missense	probably damaging	0.98
R2074:Fcgbp	UTSW	7	28,120,389 (GRCm38)	missense	probably damaging	0.98
R2124:Fcgbp	UTSW	7	28,092,019 (GRCm38)	missense	probably benign	0.03
R2155:Fcgbp	UTSW	7	28,107,203 (GRCm38)	missense	probably benign	0.00
R3015:Fcgbp	UTSW	7	28,075,413 (GRCm38)	splice site	probably benign
R3037:Fcgbp	UTSW	7	28,102,702 (GRCm38)	missense	possibly damaging	0.62
R3151:Fcgbp	UTSW	7	28,117,240 (GRCm38)	missense	probably damaging	1.00
R3176:Fcgbp	UTSW	7	28,091,661 (GRCm38)	missense	probably damaging	0.99
R3177:Fcgbp	UTSW	7	28,091,661 (GRCm38)	missense	probably damaging	0.99
R3276:Fcgbp	UTSW	7	28,091,661 (GRCm38)	missense	probably damaging	0.99
R3277:Fcgbp	UTSW	7	28,091,661 (GRCm38)	missense	probably damaging	0.99
R3623:Fcgbp	UTSW	7	28,101,276 (GRCm38)	missense	probably damaging	1.00
R3730:Fcgbp	UTSW	7	28,085,457 (GRCm38)	missense	possibly damaging	0.82
R3935:Fcgbp	UTSW	7	28,075,399 (GRCm38)	missense	probably benign	0.00
R3936:Fcgbp	UTSW	7	28,075,399 (GRCm38)	missense	probably benign	0.00
R4041:Fcgbp	UTSW	7	28,113,979 (GRCm38)	missense	probably benign	0.01
R4056:Fcgbp	UTSW	7	28,104,116 (GRCm38)	missense	probably benign	0.09
R4057:Fcgbp	UTSW	7	28,104,116 (GRCm38)	missense	probably benign	0.09
R4705:Fcgbp	UTSW	7	28,107,296 (GRCm38)	missense	probably benign	0.44
R4708:Fcgbp	UTSW	7	28,094,961 (GRCm38)	missense	probably benign	0.00
R4710:Fcgbp	UTSW	7	28,094,961 (GRCm38)	missense	probably benign	0.00
R4779:Fcgbp	UTSW	7	28,094,937 (GRCm38)	missense	probably damaging	1.00
R4820:Fcgbp	UTSW	7	28,113,958 (GRCm38)	missense	probably damaging	1.00
R4863:Fcgbp	UTSW	7	28,086,344 (GRCm38)	missense	probably benign	0.33
R4926:Fcgbp	UTSW	7	28,086,235 (GRCm38)	missense	probably damaging	0.99
R4947:Fcgbp	UTSW	7	28,089,812 (GRCm38)	missense	probably benign	0.00
R4979:Fcgbp	UTSW	7	28,117,570 (GRCm38)	missense	probably benign	0.06
R5002:Fcgbp	UTSW	7	28,086,103 (GRCm38)	splice site	probably null
R5219:Fcgbp	UTSW	7	28,104,085 (GRCm38)	missense	probably damaging	1.00
R5241:Fcgbp	UTSW	7	28,085,199 (GRCm38)	missense	probably damaging	1.00
R5301:Fcgbp	UTSW	7	28,093,674 (GRCm38)	missense	possibly damaging	0.93
R5306:Fcgbp	UTSW	7	28,091,818 (GRCm38)	missense	probably damaging	1.00
R5335:Fcgbp	UTSW	7	28,089,734 (GRCm38)	missense	probably damaging	1.00
R5399:Fcgbp	UTSW	7	28,105,055 (GRCm38)	missense	probably benign	0.05
R5418:Fcgbp	UTSW	7	28,085,313 (GRCm38)	missense	probably damaging	1.00
R5527:Fcgbp	UTSW	7	28,093,635 (GRCm38)	missense	probably benign
R5583:Fcgbp	UTSW	7	28,091,579 (GRCm38)	missense	probably damaging	1.00
R5698:Fcgbp	UTSW	7	28,092,022 (GRCm38)	missense	possibly damaging	0.95
R5780:Fcgbp	UTSW	7	28,085,218 (GRCm38)	missense	probably benign	0.02
R5813:Fcgbp	UTSW	7	28,101,494 (GRCm38)	missense	possibly damaging	0.64
R5910:Fcgbp	UTSW	7	28,085,503 (GRCm38)	splice site	probably benign
R5936:Fcgbp	UTSW	7	28,086,692 (GRCm38)	missense	probably damaging	0.98
R5992:Fcgbp	UTSW	7	28,120,534 (GRCm38)	missense	probably benign	0.05
R6091:Fcgbp	UTSW	7	28,104,965 (GRCm38)	missense	possibly damaging	0.90
R6372:Fcgbp	UTSW	7	28,107,008 (GRCm38)	missense	probably damaging	1.00
R6488:Fcgbp	UTSW	7	28,093,538 (GRCm38)	missense	probably damaging	0.96
R6548:Fcgbp	UTSW	7	28,091,918 (GRCm38)	missense	probably benign	0.00
R6553:Fcgbp	UTSW	7	28,113,979 (GRCm38)	missense	possibly damaging	0.79
R6585:Fcgbp	UTSW	7	28,113,979 (GRCm38)	missense	possibly damaging	0.79
R6695:Fcgbp	UTSW	7	28,086,270 (GRCm38)	nonsense	probably null
R6711:Fcgbp	UTSW	7	28,089,673 (GRCm38)	missense	probably damaging	0.99
R6803:Fcgbp	UTSW	7	28,103,212 (GRCm38)	missense	probably benign	0.00
R6822:Fcgbp	UTSW	7	28,107,356 (GRCm38)	missense	probably damaging	1.00
R6907:Fcgbp	UTSW	7	28,085,018 (GRCm38)	missense	probably damaging	1.00
R6912:Fcgbp	UTSW	7	28,089,704 (GRCm38)	missense	probably benign	0.15
R6924:Fcgbp	UTSW	7	28,093,823 (GRCm38)	missense	probably benign
R6943:Fcgbp	UTSW	7	28,092,052 (GRCm38)	missense	probably benign	0.22
R7060:Fcgbp	UTSW	7	28,091,933 (GRCm38)	missense	probably benign	0.20
R7103:Fcgbp	UTSW	7	28,084,962 (GRCm38)	missense	probably benign	0.00
R7208:Fcgbp	UTSW	7	28,104,021 (GRCm38)	missense	probably benign	0.01
R7291:Fcgbp	UTSW	7	28,101,392 (GRCm38)	missense	probably benign	0.00
R7301:Fcgbp	UTSW	7	28,093,436 (GRCm38)	missense	possibly damaging	0.65
R7404:Fcgbp	UTSW	7	28,101,507 (GRCm38)	missense	probably damaging	1.00
R7426:Fcgbp	UTSW	7	28,086,524 (GRCm38)	missense	probably benign	0.00
R7459:Fcgbp	UTSW	7	28,107,285 (GRCm38)	missense	possibly damaging	0.65
R7475:Fcgbp	UTSW	7	28,102,976 (GRCm38)	missense	probably damaging	0.99
R7505:Fcgbp	UTSW	7	28,089,674 (GRCm38)	missense	probably damaging	0.97
R7517:Fcgbp	UTSW	7	28,085,369 (GRCm38)	missense	probably damaging	1.00
R7519:Fcgbp	UTSW	7	28,086,299 (GRCm38)	missense	probably damaging	1.00
R7524:Fcgbp	UTSW	7	28,102,966 (GRCm38)	missense	probably damaging	1.00
R7649:Fcgbp	UTSW	7	28,091,503 (GRCm38)	missense	possibly damaging	0.88
R7782:Fcgbp	UTSW	7	28,085,035 (GRCm38)	nonsense	probably null
R7820:Fcgbp	UTSW	7	28,120,359 (GRCm38)	missense	probably benign	0.01
R7831:Fcgbp	UTSW	7	28,106,979 (GRCm38)	missense	probably damaging	0.98
R7835:Fcgbp	UTSW	7	28,117,207 (GRCm38)	missense	possibly damaging	0.64
R7947:Fcgbp	UTSW	7	28,104,170 (GRCm38)	critical splice donor site	probably null
R8086:Fcgbp	UTSW	7	28,113,964 (GRCm38)	missense	probably damaging	1.00
R8137:Fcgbp	UTSW	7	28,105,071 (GRCm38)	missense	probably damaging	1.00
R8154:Fcgbp	UTSW	7	28,085,082 (GRCm38)	missense	probably benign	0.00
R8169:Fcgbp	UTSW	7	28,085,494 (GRCm38)	critical splice donor site	probably null
R8176:Fcgbp	UTSW	7	28,091,749 (GRCm38)	missense	possibly damaging	0.88
R8193:Fcgbp	UTSW	7	28,104,851 (GRCm38)	missense	probably damaging	1.00
R8313:Fcgbp	UTSW	7	28,086,344 (GRCm38)	missense	probably benign	0.00
R8350:Fcgbp	UTSW	7	28,094,189 (GRCm38)	missense	probably benign	0.02
R8382:Fcgbp	UTSW	7	28,117,337 (GRCm38)	missense	probably benign	0.00
R8393:Fcgbp	UTSW	7	28,107,390 (GRCm38)	missense	probably benign	0.18
R8438:Fcgbp	UTSW	7	28,089,806 (GRCm38)	missense	probably benign	0.25
R8489:Fcgbp	UTSW	7	28,105,010 (GRCm38)	missense	possibly damaging	0.94
R8495:Fcgbp	UTSW	7	28,086,553 (GRCm38)	missense	probably damaging	1.00
R8707:Fcgbp	UTSW	7	28,120,495 (GRCm38)	missense	probably benign	0.01
R8736:Fcgbp	UTSW	7	28,106,196 (GRCm38)	missense	probably benign	0.05
R8816:Fcgbp	UTSW	7	28,084,987 (GRCm38)	missense	probably benign	0.09
R8905:Fcgbp	UTSW	7	28,086,509 (GRCm38)	missense	probably damaging	1.00
R9031:Fcgbp	UTSW	7	28,091,483 (GRCm38)	missense	possibly damaging	0.89
R9063:Fcgbp	UTSW	7	28,091,852 (GRCm38)	missense	probably damaging	1.00
R9180:Fcgbp	UTSW	7	28,103,773 (GRCm38)	nonsense	probably null
R9262:Fcgbp	UTSW	7	28,120,527 (GRCm38)	missense	probably damaging	1.00
R9439:Fcgbp	UTSW	7	28,104,011 (GRCm38)	missense	possibly damaging	0.60
R9526:Fcgbp	UTSW	7	28,091,512 (GRCm38)	missense	probably damaging	1.00
R9603:Fcgbp	UTSW	7	28,103,138 (GRCm38)	missense	probably damaging	1.00
R9635:Fcgbp	UTSW	7	28,101,407 (GRCm38)	missense	probably benign	0.40
R9703:Fcgbp	UTSW	7	28,106,975 (GRCm38)	missense	probably damaging	0.98
R9711:Fcgbp	UTSW	7	28,093,575 (GRCm38)	missense	probably benign	0.00
R9733:Fcgbp	UTSW	7	28,103,587 (GRCm38)	missense	probably damaging	1.00
RF002:Fcgbp	UTSW	7	28,089,755 (GRCm38)	missense	probably benign
X0028:Fcgbp	UTSW	7	28,104,020 (GRCm38)	missense	possibly damaging	0.48
Z1186:Fcgbp	UTSW	7	28,091,647 (GRCm38)	missense	probably benign
Z1186:Fcgbp	UTSW	7	28,089,755 (GRCm38)	missense	probably benign
Z1186:Fcgbp	UTSW	7	28,086,191 (GRCm38)	missense	probably benign
Z1186:Fcgbp	UTSW	7	28,103,884 (GRCm38)	missense	probably benign	0.09
Z1186:Fcgbp	UTSW	7	28,093,345 (GRCm38)	missense	probably benign

Predicted Primers

PCR Primer
(F):5'- GCTGAGTGAAAACACGAAAACCCTG -3'
(R):5'- AATTTGCTGGGTCACAAGGGAGTC -3'

Sequencing Primer
(F):5'- GAAAACCCTGACTGACCTGTTG -3'
(R):5'- ACAGTCACCAGGTTCAGTTGC -3'

Posted On

2013-07-11