Incidental Mutation 'R7167:Rims2'
| ID |
558012 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Rims2
|
| Ensembl Gene |
ENSMUSG00000037386 |
| Gene Name |
regulating synaptic membrane exocytosis 2 |
| Synonyms |
RIM2, 2810036I15Rik, Syt3-rs |
| MMRRC Submission |
045228-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly essential
(E-score: 0.539)
|
| Stock # |
R7167 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
15 |
| Chromosomal Location |
39061681-39547768 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 39300473 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Valine to Alanine
at position 260
(V260A)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000048719
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000042917]
[ENSMUST00000082054]
[ENSMUST00000227243]
[ENSMUST00000228839]
|
| AlphaFold |
Q9EQZ7 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000042917
AA Change: V260A
PolyPhen 2
Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
|
| SMART Domains |
Protein: ENSMUSP00000048719
Gene: ENSMUSG00000037386
AA Change: V260A
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
3 |
24 |
N/A |
INTRINSIC |
|
Pfam:FYVE_2
|
30 |
154 |
9.5e-18 |
PFAM |
|
low complexity region
|
315 |
335 |
N/A |
INTRINSIC |
|
low complexity region
|
492 |
498 |
N/A |
INTRINSIC |
|
low complexity region
|
511 |
521 |
N/A |
INTRINSIC |
|
low complexity region
|
527 |
540 |
N/A |
INTRINSIC |
|
PDZ
|
646 |
725 |
8.27e-16 |
SMART |
|
low complexity region
|
740 |
748 |
N/A |
INTRINSIC |
|
C2
|
790 |
897 |
4.08e-21 |
SMART |
|
low complexity region
|
905 |
919 |
N/A |
INTRINSIC |
|
low complexity region
|
1085 |
1101 |
N/A |
INTRINSIC |
|
low complexity region
|
1116 |
1130 |
N/A |
INTRINSIC |
|
low complexity region
|
1208 |
1238 |
N/A |
INTRINSIC |
|
C2
|
1432 |
1535 |
3.78e-16 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000082054
AA Change: V300A
PolyPhen 2
Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
|
| SMART Domains |
Protein: ENSMUSP00000080711
Gene: ENSMUSG00000037386
AA Change: V300A
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
3 |
24 |
N/A |
INTRINSIC |
|
Pfam:FYVE_2
|
76 |
194 |
2.2e-11 |
PFAM |
|
low complexity region
|
355 |
375 |
N/A |
INTRINSIC |
|
low complexity region
|
532 |
538 |
N/A |
INTRINSIC |
|
low complexity region
|
551 |
561 |
N/A |
INTRINSIC |
|
low complexity region
|
567 |
580 |
N/A |
INTRINSIC |
|
PDZ
|
686 |
765 |
8.27e-16 |
SMART |
|
low complexity region
|
780 |
788 |
N/A |
INTRINSIC |
|
C2
|
830 |
937 |
4.08e-21 |
SMART |
|
low complexity region
|
945 |
959 |
N/A |
INTRINSIC |
|
low complexity region
|
1075 |
1086 |
N/A |
INTRINSIC |
|
low complexity region
|
1166 |
1196 |
N/A |
INTRINSIC |
|
C2
|
1390 |
1493 |
3.78e-16 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000227243
AA Change: V260A
PolyPhen 2
Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
|
| Predicted Effect |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000228839
AA Change: V68A
PolyPhen 2
Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 100.0%
- 10x: 99.7%
- 20x: 99.1%
|
| Validation Efficiency |
94% (65/69) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene is a presynaptic protein that interacts with RAB3, a protein important for normal neurotransmitter release. The encoded protein can also bind several other synaptic proteins, including UNC-13 homolog B, ELKS/Rab6-interacting/CAST family member 1, and synaptotagmin 1. This protein is involved in synaptic membrane exocytosis. Polymorphisms in this gene have been associated with degenerative lumbar scoliosis. [provided by RefSeq, Feb 2017]
PHENOTYPE: Mice homozygous for a knock-out allele show reduced body size, aberrant insulin granule exocytosis, and impaired secretion of hormones associated with glucose homeostasis. Mice homozygous for another knock-out allele show a slightly reduced body size, abnormal maternal behavior and premature death. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 68 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| A2m |
T |
C |
6: 121,624,930 (GRCm39) |
V436A |
probably benign |
Het |
| Abcc5 |
T |
C |
16: 20,224,251 (GRCm39) |
T111A |
possibly damaging |
Het |
| Acsbg2 |
T |
A |
17: 57,164,000 (GRCm39) |
D203V |
probably benign |
Het |
| Alpk2 |
G |
T |
18: 65,440,049 (GRCm39) |
T448K |
probably benign |
Het |
| Arhgef2 |
A |
G |
3: 88,551,179 (GRCm39) |
N780S |
possibly damaging |
Het |
| Atxn2l |
T |
C |
7: 126,098,394 (GRCm39) |
N252S |
possibly damaging |
Het |
| Bmpr1b |
A |
T |
3: 141,568,841 (GRCm39) |
L163Q |
probably benign |
Het |
| Clca3a2 |
T |
C |
3: 144,803,545 (GRCm39) |
R100G |
probably benign |
Het |
| Col2a1 |
A |
G |
15: 97,898,337 (GRCm39) |
I79T |
unknown |
Het |
| Csmd1 |
A |
G |
8: 15,976,524 (GRCm39) |
V2898A |
probably benign |
Het |
| Cux1 |
G |
A |
5: 136,338,895 (GRCm39) |
|
probably null |
Het |
| Cyp2u1 |
A |
G |
3: 131,096,773 (GRCm39) |
S2P |
probably benign |
Het |
| Daam1 |
C |
A |
12: 72,035,678 (GRCm39) |
H958N |
probably damaging |
Het |
| Dnah7a |
C |
T |
1: 53,542,935 (GRCm39) |
V2412I |
probably benign |
Het |
| Ergic2 |
T |
C |
6: 148,108,133 (GRCm39) |
R2G |
probably damaging |
Het |
| Fat2 |
T |
C |
11: 55,175,827 (GRCm39) |
T1629A |
possibly damaging |
Het |
| Ftl1 |
T |
A |
7: 45,109,202 (GRCm39) |
|
probably benign |
Het |
| Fut8 |
T |
C |
12: 77,495,406 (GRCm39) |
V332A |
possibly damaging |
Het |
| Gm28363 |
T |
C |
1: 117,655,119 (GRCm39) |
S113P |
probably damaging |
Het |
| Hfe |
A |
T |
13: 23,892,052 (GRCm39) |
V104E |
probably damaging |
Het |
| Ifih1 |
A |
T |
2: 62,429,240 (GRCm39) |
N899K |
probably benign |
Het |
| Krt75 |
A |
G |
15: 101,476,750 (GRCm39) |
S380P |
possibly damaging |
Het |
| Meiob |
T |
G |
17: 25,055,419 (GRCm39) |
F409V |
probably damaging |
Het |
| Mkrn2os |
A |
T |
6: 115,562,474 (GRCm39) |
I163N |
probably damaging |
Het |
| Nanos1 |
G |
T |
19: 60,745,046 (GRCm39) |
G115W |
probably damaging |
Het |
| Naprt |
C |
T |
15: 75,764,461 (GRCm39) |
A276T |
probably damaging |
Het |
| Oas1e |
G |
T |
5: 120,933,487 (GRCm39) |
T26N |
probably benign |
Het |
| Oog2 |
T |
G |
4: 143,921,745 (GRCm39) |
D218E |
probably benign |
Het |
| Optn |
T |
C |
2: 5,047,294 (GRCm39) |
N207S |
probably benign |
Het |
| Or13a20 |
T |
A |
7: 140,232,466 (GRCm39) |
C191* |
probably null |
Het |
| Or1l8 |
T |
C |
2: 36,817,533 (GRCm39) |
I198V |
probably benign |
Het |
| Or4g16 |
T |
C |
2: 111,136,793 (GRCm39) |
M81T |
probably benign |
Het |
| Or4p18 |
A |
G |
2: 88,232,552 (GRCm39) |
V242A |
possibly damaging |
Het |
| Or6c63-ps1 |
T |
G |
10: 128,899,141 (GRCm39) |
Q245P |
probably damaging |
Het |
| Or6c66b |
T |
C |
10: 129,376,607 (GRCm39) |
L67P |
possibly damaging |
Het |
| Or8g4 |
T |
C |
9: 39,661,865 (GRCm39) |
F61S |
probably damaging |
Het |
| Oxnad1 |
G |
T |
14: 31,822,976 (GRCm39) |
E236* |
probably null |
Het |
| Pcdha3 |
G |
A |
18: 37,080,046 (GRCm39) |
A263T |
probably damaging |
Het |
| Pex13 |
A |
T |
11: 23,605,472 (GRCm39) |
W253R |
possibly damaging |
Het |
| Pip5k1b |
T |
A |
19: 24,374,433 (GRCm39) |
E49D |
probably benign |
Het |
| Plau |
C |
A |
14: 20,889,518 (GRCm39) |
F194L |
possibly damaging |
Het |
| Ppm1n |
A |
G |
7: 19,013,666 (GRCm39) |
L95S |
probably damaging |
Het |
| Pramel40 |
G |
A |
5: 94,464,984 (GRCm39) |
A457T |
possibly damaging |
Het |
| Radil |
G |
T |
5: 142,471,260 (GRCm39) |
|
probably null |
Het |
| Ralgapa2 |
C |
T |
2: 146,190,374 (GRCm39) |
M1266I |
probably benign |
Het |
| Reln |
A |
T |
5: 22,147,618 (GRCm39) |
L2444Q |
probably damaging |
Het |
| Rnase2b |
T |
A |
14: 51,400,222 (GRCm39) |
V101E |
probably damaging |
Het |
| Rtp3 |
T |
A |
9: 110,815,772 (GRCm39) |
T198S |
probably benign |
Het |
| Shisal2b |
A |
G |
13: 105,000,166 (GRCm39) |
V19A |
probably damaging |
Het |
| Smad3 |
T |
A |
9: 63,573,435 (GRCm39) |
D201V |
probably benign |
Het |
| Son |
AGAACCCCCAGCCGCAGGAGCCGAACCCCCAGCCGCAGGAGCCGAACCCCCAGCCGCAGGAGCCGAACCCCCAGCCG |
AGAACCCCCAGCCGCAGGAGCCGAACCCCCAGCCGCAGGAGCCGAACCCCCAGCCG |
16: 91,457,222 (GRCm39) |
|
probably benign |
Het |
| Spata7 |
T |
G |
12: 98,630,555 (GRCm39) |
F371C |
probably damaging |
Het |
| Stag1 |
T |
G |
9: 100,827,942 (GRCm39) |
N990K |
probably benign |
Het |
| Tbx18 |
C |
T |
9: 87,589,883 (GRCm39) |
A352T |
probably damaging |
Het |
| Thada |
C |
T |
17: 84,538,391 (GRCm39) |
R1539Q |
probably benign |
Het |
| Thrap3 |
A |
C |
4: 126,078,920 (GRCm39) |
|
probably benign |
Het |
| Tnks |
G |
A |
8: 35,316,458 (GRCm39) |
T887M |
probably damaging |
Het |
| Trap1 |
A |
C |
16: 3,870,792 (GRCm39) |
V393G |
probably damaging |
Het |
| Trpm4 |
A |
G |
7: 44,977,143 (GRCm39) |
|
probably null |
Het |
| Trrap |
G |
T |
5: 144,776,424 (GRCm39) |
G3007C |
probably benign |
Het |
| U2surp |
A |
T |
9: 95,363,726 (GRCm39) |
N611K |
probably damaging |
Het |
| Usp12 |
A |
G |
5: 146,705,745 (GRCm39) |
|
probably null |
Het |
| Vmn1r200 |
A |
G |
13: 22,579,487 (GRCm39) |
T97A |
possibly damaging |
Het |
| Vmn2r110 |
C |
T |
17: 20,794,441 (GRCm39) |
V743I |
probably benign |
Het |
| Vps50 |
C |
T |
6: 3,600,256 (GRCm39) |
T905M |
probably damaging |
Het |
| Wdr48 |
T |
A |
9: 119,736,855 (GRCm39) |
|
probably null |
Het |
| Zfp446 |
C |
T |
7: 12,712,049 (GRCm39) |
|
probably benign |
Het |
| Zfr |
T |
C |
15: 12,181,015 (GRCm39) |
S1012P |
probably benign |
Het |
|
| Other mutations in Rims2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00339:Rims2
|
APN |
15 |
39,323,011 (GRCm39) |
missense |
probably benign |
0.11 |
|
IGL00502:Rims2
|
APN |
15 |
39,370,380 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00556:Rims2
|
APN |
15 |
39,320,070 (GRCm39) |
splice site |
probably null |
|
|
IGL00811:Rims2
|
APN |
15 |
39,155,544 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00827:Rims2
|
APN |
15 |
39,335,755 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01642:Rims2
|
APN |
15 |
39,321,192 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02951:Rims2
|
APN |
15 |
39,398,334 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03009:Rims2
|
APN |
15 |
39,430,393 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
IGL03080:Rims2
|
APN |
15 |
39,399,299 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03102:Rims2
|
APN |
15 |
39,322,989 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
IGL03252:Rims2
|
APN |
15 |
39,315,748 (GRCm39) |
missense |
probably benign |
|
|
IGL03365:Rims2
|
APN |
15 |
39,339,937 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03393:Rims2
|
APN |
15 |
39,326,009 (GRCm39) |
splice site |
probably null |
|
|
IGL03409:Rims2
|
APN |
15 |
39,320,129 (GRCm39) |
missense |
probably damaging |
1.00 |
|
rhyme
|
UTSW |
15 |
39,315,724 (GRCm39) |
missense |
probably damaging |
1.00 |
|
PIT4486001:Rims2
|
UTSW |
15 |
39,339,916 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
R0009:Rims2
|
UTSW |
15 |
39,398,362 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0009:Rims2
|
UTSW |
15 |
39,398,362 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0078:Rims2
|
UTSW |
15 |
39,398,251 (GRCm39) |
missense |
probably benign |
0.42 |
|
R0367:Rims2
|
UTSW |
15 |
39,326,011 (GRCm39) |
splice site |
probably null |
|
|
R0401:Rims2
|
UTSW |
15 |
39,373,028 (GRCm39) |
splice site |
probably benign |
|
|
R0531:Rims2
|
UTSW |
15 |
39,430,426 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0791:Rims2
|
UTSW |
15 |
39,543,021 (GRCm39) |
splice site |
probably benign |
|
|
R0838:Rims2
|
UTSW |
15 |
39,544,421 (GRCm39) |
missense |
probably benign |
0.02 |
|
R1201:Rims2
|
UTSW |
15 |
39,479,720 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R1318:Rims2
|
UTSW |
15 |
39,381,222 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1457:Rims2
|
UTSW |
15 |
39,374,710 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R1619:Rims2
|
UTSW |
15 |
39,370,382 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1672:Rims2
|
UTSW |
15 |
39,155,584 (GRCm39) |
missense |
probably benign |
0.09 |
|
R1743:Rims2
|
UTSW |
15 |
39,543,046 (GRCm39) |
missense |
probably benign |
0.10 |
|
R1766:Rims2
|
UTSW |
15 |
39,325,976 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1779:Rims2
|
UTSW |
15 |
39,545,098 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1804:Rims2
|
UTSW |
15 |
39,300,439 (GRCm39) |
nonsense |
probably null |
|
|
R1985:Rims2
|
UTSW |
15 |
39,208,710 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1986:Rims2
|
UTSW |
15 |
39,208,710 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2113:Rims2
|
UTSW |
15 |
39,374,722 (GRCm39) |
missense |
probably benign |
0.17 |
|
R2260:Rims2
|
UTSW |
15 |
39,341,962 (GRCm39) |
nonsense |
probably null |
|
|
R2510:Rims2
|
UTSW |
15 |
39,449,048 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3693:Rims2
|
UTSW |
15 |
39,341,971 (GRCm39) |
missense |
probably benign |
0.01 |
|
R3937:Rims2
|
UTSW |
15 |
39,301,241 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4425:Rims2
|
UTSW |
15 |
39,301,320 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4453:Rims2
|
UTSW |
15 |
39,155,603 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4474:Rims2
|
UTSW |
15 |
39,325,956 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4518:Rims2
|
UTSW |
15 |
39,300,922 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4526:Rims2
|
UTSW |
15 |
39,301,113 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4833:Rims2
|
UTSW |
15 |
39,399,310 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R4936:Rims2
|
UTSW |
15 |
39,301,124 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4993:Rims2
|
UTSW |
15 |
39,317,841 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R5001:Rims2
|
UTSW |
15 |
39,315,824 (GRCm39) |
missense |
probably benign |
0.03 |
|
R5054:Rims2
|
UTSW |
15 |
39,381,265 (GRCm39) |
splice site |
probably null |
|
|
R5072:Rims2
|
UTSW |
15 |
39,325,986 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5171:Rims2
|
UTSW |
15 |
39,300,499 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5429:Rims2
|
UTSW |
15 |
39,208,751 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5623:Rims2
|
UTSW |
15 |
39,342,011 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5624:Rims2
|
UTSW |
15 |
39,208,809 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R5685:Rims2
|
UTSW |
15 |
39,300,602 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
R5784:Rims2
|
UTSW |
15 |
39,399,383 (GRCm39) |
splice site |
probably null |
|
|
R5790:Rims2
|
UTSW |
15 |
39,544,441 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5822:Rims2
|
UTSW |
15 |
39,339,886 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5963:Rims2
|
UTSW |
15 |
39,300,578 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5988:Rims2
|
UTSW |
15 |
39,155,577 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6057:Rims2
|
UTSW |
15 |
39,538,416 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6239:Rims2
|
UTSW |
15 |
39,061,758 (GRCm39) |
start codon destroyed |
unknown |
|
|
R6407:Rims2
|
UTSW |
15 |
39,315,724 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6418:Rims2
|
UTSW |
15 |
39,373,092 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6495:Rims2
|
UTSW |
15 |
39,381,208 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6502:Rims2
|
UTSW |
15 |
39,398,251 (GRCm39) |
missense |
probably benign |
0.42 |
|
R6753:Rims2
|
UTSW |
15 |
39,430,369 (GRCm39) |
missense |
possibly damaging |
0.74 |
|
R6855:Rims2
|
UTSW |
15 |
39,208,911 (GRCm39) |
missense |
probably benign |
0.06 |
|
R6948:Rims2
|
UTSW |
15 |
39,374,737 (GRCm39) |
missense |
probably benign |
|
|
R7058:Rims2
|
UTSW |
15 |
39,449,044 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7217:Rims2
|
UTSW |
15 |
39,339,885 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7223:Rims2
|
UTSW |
15 |
39,300,428 (GRCm39) |
missense |
probably benign |
0.30 |
|
R7289:Rims2
|
UTSW |
15 |
39,301,114 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7459:Rims2
|
UTSW |
15 |
39,381,235 (GRCm39) |
missense |
probably benign |
|
|
R7663:Rims2
|
UTSW |
15 |
39,370,422 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7792:Rims2
|
UTSW |
15 |
39,061,923 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R7836:Rims2
|
UTSW |
15 |
39,544,475 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8082:Rims2
|
UTSW |
15 |
39,339,919 (GRCm39) |
missense |
probably benign |
0.34 |
|
R8489:Rims2
|
UTSW |
15 |
39,479,846 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8730:Rims2
|
UTSW |
15 |
39,381,239 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8830:Rims2
|
UTSW |
15 |
39,300,758 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
R8857:Rims2
|
UTSW |
15 |
39,543,044 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R8893:Rims2
|
UTSW |
15 |
39,398,350 (GRCm39) |
missense |
probably benign |
0.02 |
|
R9010:Rims2
|
UTSW |
15 |
39,315,786 (GRCm39) |
nonsense |
probably null |
|
|
R9030:Rims2
|
UTSW |
15 |
39,339,873 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9287:Rims2
|
UTSW |
15 |
39,543,086 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9395:Rims2
|
UTSW |
15 |
39,155,664 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9451:Rims2
|
UTSW |
15 |
39,300,724 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9506:Rims2
|
UTSW |
15 |
39,335,832 (GRCm39) |
missense |
probably damaging |
0.97 |
|
X0034:Rims2
|
UTSW |
15 |
39,300,930 (GRCm39) |
missense |
probably benign |
|
|
Z1177:Rims2
|
UTSW |
15 |
39,544,510 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Rims2
|
UTSW |
15 |
39,342,086 (GRCm39) |
frame shift |
probably null |
|
|
Z1177:Rims2
|
UTSW |
15 |
39,301,165 (GRCm39) |
missense |
probably benign |
0.24 |
|
| Predicted Primers |
PCR Primer
(F):5'- AAGATCTGCTTGAATTTATCCACCC -3'
(R):5'- TGGATCACTTCTGTAGCGTGC -3'
Sequencing Primer
(F):5'- CCCATTTGGCAGTGAATCAG -3'
(R):5'- GTAGCGTGCCTGGTATTCCTC -3'
|
| Posted On |
2019-06-26 |
Incidental Mutation